Page last updated: 2024-09-03

n(6)-carboxymethyllysine and thioctic acid

n(6)-carboxymethyllysine has been researched along with thioctic acid in 4 studies

Compound Research Comparison

Studies
(n(6)-carboxymethyllysine)
Trials
(n(6)-carboxymethyllysine)
Recent Studies (post-2010)
(n(6)-carboxymethyllysine)
Studies
(thioctic acid)
Trials
(thioctic acid)
Recent Studies (post-2010) (thioctic acid)
803443654,6283221,947

Protein Interaction Comparison

ProteinTaxonomyn(6)-carboxymethyllysine (IC50)thioctic acid (IC50)
Ubiquitin-like modifier activating enzyme 2Homo sapiens (human)2.68
SUMO1 activating enzyme subunit 1Homo sapiens (human)2.68
hexokinaseTrypanosoma brucei brucei TREU9270.2008
SUMO-conjugating enzyme UBC9Homo sapiens (human)2.68
eukaryotic translation initiation factor 4 gamma 1 isoform 4Homo sapiens (human)16.56
eukaryotic translation initiation factor 4E isoform 1Mus musculus (house mouse)16.56
VifHuman immunodeficiency virus 17.67
TatHuman immunodeficiency virus 15.891
DNA dC->dU-editing enzyme APOBEC-3G isoform 1Homo sapiens (human)7.67
bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferaseMycobacterium tuberculosis H37Rv3.91

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nerlich, AG; Schleicher, ED; Wagner, E1
Funk, RH; Geffarth, R; Kasper, M; Reber, F; Reichenbach, A; Schleicher, ED; Siegner, A1
Chang, CR; Chen, MH; Kao, SH; Lee, HM; Lee, WS; Lo, MC; Lu, CI1
Chen, MH; Hsueh, YT; Kuo, YT; Lee, HM; Lo, MC1

Other Studies

4 other study(ies) available for n(6)-carboxymethyllysine and thioctic acid

ArticleYear
Increased accumulation of the glycoxidation product N(epsilon)-(carboxymethyl)lysine in human tissues in diabetes and aging.
    The Journal of clinical investigation, 1997, Feb-01, Volume: 99, Issue:3

    Topics: Adult; Aged; Aging; Antibodies; Arteries; Arteriosclerosis; Biomarkers; Blood Proteins; Catalase; Child; Deferoxamine; Diabetes Mellitus; Enzyme-Linked Immunosorbent Assay; Epitopes; Female; Fetus; Foam Cells; Guanidines; Humans; Immunohistochemistry; Intervertebral Disc; Intestinal Mucosa; Kidney; Lung; Lysine; Middle Aged; Molecular Structure; Myocardium; Oxidation-Reduction; Oxidative Stress; Pregnancy; Skin; Superoxide Dismutase; Thioctic Acid; Time Factors; Vitamin E

1997
Graded sensitiveness of the various retinal neuron populations on the glyoxal-mediated formation of advanced glycation end products and ways of protection.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2003, Volume: 241, Issue:3

    Topics: Acetylcysteine; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspases; Dose-Response Relationship, Drug; Female; Glycation End Products, Advanced; Glyoxal; Guanidines; Immunoenzyme Techniques; In Situ Nick-End Labeling; Lysine; Male; Neurons; Niacinamide; Organ Culture Techniques; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Retina; Thioctic Acid; Vanadates

2003
Nε-(carboxymethyl) lysine-induced mitochondrial fission and mitophagy cause decreased insulin secretion from β-cells.
    American journal of physiology. Endocrinology and metabolism, 2015, Nov-15, Volume: 309, Issue:10

    Topics: Animals; Antioxidants; Biomarkers; Cell Line, Tumor; Diabetes Mellitus; Dietary Supplements; Down-Regulation; Glycation End Products, Advanced; Insulin; Insulin Secretion; Insulin-Secreting Cells; Lysine; Male; Mice, Inbred C57BL; Mice, Mutant Strains; Mitochondrial Dynamics; Mitophagy; Oxidants; Phagosomes; Rats; Receptor for Advanced Glycation End Products; Serum Albumin, Bovine; Thioctic Acid

2015
Alpha-lipoic acid suppresses N
    Free radical research, 2018, Volume: 52, Issue:11-12

    Topics: Cells, Cultured; Epithelial-Mesenchymal Transition; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Kidney Tubules, Proximal; Lysine; Reactive Oxygen Species; Thioctic Acid

2018