n(6)-carboxymethyllysine has been researched along with pimagedine in 20 studies
| Studies (n(6)-carboxymethyllysine) | Trials (n(6)-carboxymethyllysine) | Recent Studies (post-2010) (n(6)-carboxymethyllysine) | Studies (pimagedine) | Trials (pimagedine) | Recent Studies (post-2010) (pimagedine) |
|---|---|---|---|---|---|
| 803 | 44 | 365 | 2,162 | 18 | 390 |
| Protein | Taxonomy | n(6)-carboxymethyllysine (IC50) | pimagedine (IC50) |
|---|---|---|---|
| Nitric oxide synthase, brain | Homo sapiens (human) | 5.9 | |
| Nitric oxide synthase, inducible | Homo sapiens (human) | 4.2 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (15.00) | 18.2507 |
| 2000's | 12 (60.00) | 29.6817 |
| 2010's | 4 (20.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nerlich, AG; Schleicher, ED; Wagner, E | 1 |
| Kurokawa, K; Mitsuma, T; Miyata, T; Niwa, H; Sobue, G; Takeda, A; Wakai, M; Yasuda, Y | 1 |
| Monnier, VM; Saxena, AK; Weiss, MF | 1 |
| Araki, A; Deoreo, PB; Erhard, P; Glomb, MA; Kader-Attia, FA; Monnier, VM; Weiss, MF; Wu, YC | 1 |
| Arakawa, K; Horiuchi, S; Imanaga, Y; Itabe, H; Matsunaga, A; Nagai, R; Sakata, N; Sasaki, J; Takano, T; Takebayashi, S | 1 |
| Asahi, K; Inagi, R; Izuhara, Y; Kurokawa, K; Miyata, T; Saito, A; Ueda, Y; VAN Ypersele DE Strihou, C | 1 |
| Horiuchi, S; Itabe, H; Jono, T; Myint, T; Nagai, R; Sakata, N; Takano, T; Takebayashi, S; Takeya, M; Taniguchi, N; Uesugi, N | 1 |
| Amano, S; Horiuchi, S; Kaji, Y; Nagai, R; Oshika, T; Suzuki, K; Tanaka, S; Usui, T | 1 |
| Araki, T; Hayase, F; Horiuchi, S; Miki Hayashi, C; Miyazaki, K; Nagai, R; Ono, T | 1 |
| Hayase, F; Hayashi, MC; Horiuchi, S; Kinae, N; Masuda, S; Nagai, R; Unno, Y | 1 |
| Brammar, G; Burns, WC; Cao, Z; Cooper, ME; Forbes, JM; MCLennan, SV; Twigg, SM | 1 |
| Funk, RH; Geffarth, R; Kasper, M; Reber, F; Reichenbach, A; Schleicher, ED; Siegner, A | 1 |
| Ferreira, AE; Ponces Freire, AM; Voit, EO | 1 |
| Machado, AP; Moysés, ZP; Nakandakare, ER; Passarelli, M; Pinto, RS; Quintão, EC | 1 |
| Kang, KS; Kim, HY; Yamabe, N; Yokozawa, T | 1 |
| Anderson, G; Baumann, M; Heemann, U; Hermans, R; Lutz, J; Schmaderer, C; Xing, CJ | 1 |
| Bloemen, JG; Buurman, WA; Dejong, CH; Driessen, A; Gaens, KH; Greve, JW; Hofker, MH; Niessen, PM; Rensen, SS; Schalkwijk, CG; Stehouwer, CD; Wolfs, MG | 1 |
| Bidasee, KR; Kutty, S; Moore, CJ; Nagai, R; Shao, CH; Singh, J | 1 |
| André-Frei, V; Bechetoille, N; Berthod, F; Cadau, S; Leoty-Okombi, S; Pain, S | 1 |
| Ahmad, S; Akashah, R; Alouffi, S; Faisal, M; Khan, M; Khan, MS; Khan, S; Shahab, U | 1 |
20 other study(ies) available for n(6)-carboxymethyllysine and pimagedine
| Article | Year |
|---|---|
Increased accumulation of the glycoxidation product N(epsilon)-(carboxymethyl)lysine in human tissues in diabetes and aging.
Topics: Adult; Aged; Aging; Antibodies; Arteries; Arteriosclerosis; Biomarkers; Blood Proteins; Catalase; Child; Deferoxamine; Diabetes Mellitus; Enzyme-Linked Immunosorbent Assay; Epitopes; Female; Fetus; Foam Cells; Guanidines; Humans; Immunohistochemistry; Intervertebral Disc; Intestinal Mucosa; Kidney; Lung; Lysine; Middle Aged; Molecular Structure; Myocardium; Oxidation-Reduction; Oxidative Stress; Pregnancy; Skin; Superoxide Dismutase; Thioctic Acid; Time Factors; Vitamin E | 1997 |
Accelerated formation of N epsilon-(carboxymethyl) lysine, an advanced glycation end product, by glyoxal and 3-deoxyglucosone in cultured rat sensory neurons.
Topics: Animals; Apoptosis; Culture Techniques; Deoxyglucose; Dose-Response Relationship, Drug; Ganglia, Spinal; Glycation End Products, Advanced; Glyoxal; Guanidines; Lysine; Neurons, Afferent; Rats; Rats, Sprague-Dawley | 1998 |
Pharmacological modulation of AGEs: a unique role for redox-active metal ions.
Topics: Animals; Antioxidants; Chelating Agents; Diabetes Mellitus; Glycation End Products, Advanced; Guanidines; Humans; Kidney Failure, Chronic; Lysine; Metals; Oxidation-Reduction; Oxidative Stress; Peritoneal Dialysis; Uremia | 1999 |
Mechanisms for the formation of glycoxidation products in end-stage renal disease.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Enzyme Inhibitors; Female; Glucose; Glycation End Products, Advanced; Guanidines; Humans; Kidney Failure, Chronic; Lysine; Maillard Reaction; Male; Middle Aged; Oxidation-Reduction; Peritoneal Dialysis; Renal Dialysis | 2000 |
In vivo and in vitro evidence for the glycoxidation of low density lipoprotein in human atherosclerotic plaques.
Topics: Adolescent; Adult; Aged; Antibodies, Monoclonal; Aortic Diseases; Arteriosclerosis; Chelating Agents; Child; Child, Preschool; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Epitopes; Female; Glycation End Products, Advanced; Glycosylation; Guanidines; Humans; Infant; Lipoproteins, LDL; Lysine; Male; Middle Aged; Nitric Oxide Synthase; Phosphatidylcholines; Thiobarbituric Acid Reactive Substances | 2000 |
Mechanism of the inhibitory effect of OPB-9195 [(+/-)-2-isopropylidenehydrazono-4-oxo-thiazolidin-5-yla cetanilide] on advanced glycation end product and advanced lipoxidation end product formation.
Topics: Aldehydes; Arachidonic Acid; Arginine; Deoxyglucose; Dialysis Solutions; Glycation End Products, Advanced; Glyoxal; Guanidines; Lipid Metabolism; Lysine; Malondialdehyde; Oxidation-Reduction; Peritoneal Dialysis; Prodrugs; Pyruvaldehyde; Thiadiazoles; Thiazolidines | 2000 |
Glycoxidation and lipid peroxidation of low-density lipoprotein can synergistically enhance atherogenesis.
Topics: Adult; Aged; Aged, 80 and over; Arteriosclerosis; Chelating Agents; Copper; Edetic Acid; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Glucose; Guanidines; Humans; Immunohistochemistry; Lipid Peroxidation; Lipoproteins, LDL; Lysine; Male; Malondialdehyde; Middle Aged; Pentetic Acid; Receptors, Immunologic; Receptors, Scavenger | 2001 |
Advanced glycation end products in Descemet's membrane and their effect on corneal endothelial cell.
Topics: Animals; Antibodies, Monoclonal; Cattle; Cell Adhesion; Cell Division; Cells, Cultured; Collagen Type I; Collagen Type IV; Descemet Membrane; Endothelium, Corneal; Enzyme-Linked Immunosorbent Assay; Fibronectins; Glycation End Products, Advanced; Glycosylation; Guanidines; Immunoenzyme Techniques; Laminin; Lysine | 2001 |
Conversion of Amadori products of the Maillard reaction to N(epsilon)-(carboxymethyl)lysine by short-term heating: possible detection of artifacts by immunohistochemistry.
Topics: Animals; Antibodies, Monoclonal; Artifacts; Borohydrides; Glycation End Products, Advanced; Guanidines; Hot Temperature; Humans; Immunoenzyme Techniques; Liver; Lysine; Maillard Reaction; Male; Polyamines; Rats; Rats, Wistar; Serum Albumin; Skin | 2002 |
Peroxynitrite induces formation of N( epsilon )-(carboxymethyl) lysine by the cleavage of Amadori product and generation of glucosone and glyoxal from glucose: novel pathways for protein modification by peroxynitrite.
Topics: 2-Naphthylamine; Aldehydes; Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Glucose; Glyoxal; Guanidines; Ketoses; Lysine; Mice; Mice, Inbred BALB C; Peroxynitrous Acid; Serum Albumin; Tyrosine | 2002 |
Renal connective tissue growth factor induction in experimental diabetes is prevented by aminoguanidine.
Topics: Animals; Cells, Cultured; Connective Tissue Growth Factor; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fibronectins; Gene Expression; Glomerular Mesangium; Glycation End Products, Advanced; Guanidines; Humans; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Kidney; Lysine; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Serum Albumin, Bovine | 2002 |
Graded sensitiveness of the various retinal neuron populations on the glyoxal-mediated formation of advanced glycation end products and ways of protection.
Topics: Acetylcysteine; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspases; Dose-Response Relationship, Drug; Female; Glycation End Products, Advanced; Glyoxal; Guanidines; Immunoenzyme Techniques; In Situ Nick-End Labeling; Lysine; Male; Neurons; Niacinamide; Organ Culture Techniques; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Retina; Thioctic Acid; Vanadates | 2003 |
A quantitative model of the generation of N(epsilon)-(carboxymethyl)lysine in the Maillard reaction between collagen and glucose.
Topics: Collagen; Glucose; Glycation End Products, Advanced; Guanidines; Kinetics; Lysine; Maillard Reaction; Models, Theoretical | 2003 |
Aminoguanidine and metformin prevent the reduced rate of HDL-mediated cell cholesterol efflux induced by formation of advanced glycation end products.
Topics: Albumins; Animals; Atherosclerosis; Cells, Cultured; Cholesterol, HDL; Diabetes Mellitus; Enzyme Inhibitors; Glycation End Products, Advanced; Guanidines; Humans; Hypoglycemic Agents; Lysine; Macrophages, Peritoneal; Metformin; Mice | 2006 |
Role of maltol in advanced glycation end products and free radicals: in-vitro and in-vivo studies.
Topics: Animals; Blood Glucose; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Glycated Serum Albumin; Glycation End Products, Advanced; Guanidines; Lysine; Male; Proteinuria; Pyrones; Rats; Rats, Wistar; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Serum Albumin; Streptozocin; Transcription Factor RelA | 2008 |
AGE formation blockade with aminoguanidine does not ameliorate chronic allograft nephropathy.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Cardiotonic Agents; Dinoprost; Enzyme Inhibitors; Glycation End Products, Advanced; Guanidines; Hydroxyproline; Kidney Diseases; Kidney Function Tests; Kidney Transplantation; Lysine; Male; Oxidative Stress; Proteinuria; Rats; Rats, Inbred F344; Rats, Inbred Lew; Tetrazoles; Time Factors; Transplantation, Homologous | 2011 |
Endogenous formation of Nε-(carboxymethyl)lysine is increased in fatty livers and induces inflammatory markers in an in vitro model of hepatic steatosis.
Topics: Aged; Biomarkers; Biopsy; Cytokines; Enzyme Inhibitors; Fatty Liver; Female; Gene Expression; Guanidines; Hep G2 Cells; Hepatocytes; Humans; In Vitro Techniques; Liver; Lysine; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Obesity; Pyridoxamine; Vitamin B Complex | 2012 |
Malondialdehyde and 4-hydroxynonenal adducts are not formed on cardiac ryanodine receptor (RyR2) and sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA2) in diabetes.
Topics: Aldehydes; Animals; Arginine; Calcium; Cyclic N-Oxides; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Echocardiography; Guanidines; Lysine; Male; Malondialdehyde; Myocytes, Cardiac; Norleucine; Protein Carbonylation; Pyridoxamine; Pyrroles; Rats; Rats, Sprague-Dawley; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Spin Labels | 2013 |
In vitro glycation of an endothelialized and innervated tissue-engineered skin to screen anti-AGE molecules.
Topics: Animals; Capillaries; Cattle; Cell Differentiation; Cells, Cultured; Collagen; Cytoskeleton; Dermis; Endothelial Cells; Fibroblasts; Filaggrin Proteins; Glycation End Products, Advanced; Glycosylation; Glyoxal; Guanidines; Humans; Keratinocytes; Lysine; Mice; Neurons; Protective Agents; Skin; Thiazoles; Tissue Engineering | 2015 |
Gold Nanoparticle-Bioconjugated Aminoguanidine Inhibits Glycation Reaction: An
Topics: Animals; Blood Glucose; Diabetes Complications; Diabetes Mellitus, Experimental; Disease Models, Animal; Glycation End Products, Advanced; Glycosylation; Gold; Guanidines; Lysine; Male; Metal Nanoparticles; Proteins; Pyruvaldehyde; Rats; Rats, Wistar | 2021 |