Page last updated: 2024-09-03

n(6)-carboxymethyllysine and malondialdehyde

n(6)-carboxymethyllysine has been researched along with malondialdehyde in 29 studies

Compound Research Comparison

Studies
(n(6)-carboxymethyllysine)
Trials
(n(6)-carboxymethyllysine)
Recent Studies (post-2010)
(n(6)-carboxymethyllysine)
Studies
(malondialdehyde)
Trials
(malondialdehyde)
Recent Studies (post-2010) (malondialdehyde)
8034436527,8491,40513,922

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (31.03)18.2507
2000's13 (44.83)29.6817
2010's6 (20.69)24.3611
2020's1 (3.45)2.80

Authors

AuthorsStudies
Bailey, AJ; Paul, RG1
Ahmed, MU; Fu, MX; Jenkins, AJ; Lyons, TJ; Requena, JR; Thorpe, SR1
Horie, K; Kurokawa, K; Maeda, K; Miyata, S; Miyata, T; Monnier, VM; Sakai, H; Sugiyama, S; van Ypersole de Strihou, C; Witztum, JL1
Asano, T; Futata, T; Horiuchi, S; Ikeda, K; Meng, J; Myint, T; Nagai, R; Sakata, N; Takebayashi, S; Taniguchi, N1
Baynes, JW; Fu, MX; Kurokawa, K; Miyata, T; Thorpe, SR; van Ypersele de Strihou, C1
Hermon, M; Hoeger, H; Lubec, B; Lubec, G1
Horie, K; Inagi, R; Izuhara, Y; Kurokawa, K; Miyata, T; Sakai, H; Saotome, N; Suzuki, D; Uchida, K; Yagame, M; Yasuda, Y1
Inagi, R; Kurokawa, K; Miyata, T; Sugiyama, S; Suzuki, D1
Barja, G; Baynes, JW; Bellmunt, MJ; López-Torres, M; Pamplona, R; Portero-Otín, M; Requena, JR; Romero, M; Ruiz, C; Thorpe, SR1
Asahi, K; Inagi, R; Izuhara, Y; Kurokawa, K; Miyata, T; Saito, A; Ueda, Y; VAN Ypersele DE Strihou, C1
Horiuchi, S; Itabe, H; Jono, T; Myint, T; Nagai, R; Sakata, N; Takano, T; Takebayashi, S; Takeya, M; Taniguchi, N; Uesugi, N1
Blazícek, P; Heidland, A; Krivosíková, Z; Schinzel, R; Sebeková, K; Spustová, V; Syrová, D1
Blazícek, P; Boor, P; Bozek, P; Heidland, A; Pecovová, A; Schinzel, R; Sebeková, K; Syrová, D1
Barja, G; Bellmun, MJ; Gredilla, R; Pamplona, R; Portero-Otín, M1
Dei, R; Horie, K; Inagaki, T; Li, M; Miyata, T; Nakagomi, Y; Niwa, H; Sobue, G; Takeda, A; Washimi, Y; Watanabe, M; Yasuda, Y1
Moh, A; Sakata, N; Takebayashi, S1
Koo, JR; Vaziri, ND1
Blazícek, P; Dzúrik, R; Gazdíková, K; Heidland, A; Schinzel, R; Sebeková, K; Spustová, V; Syrová, D1
Chassereau, C; Derrick, MB; Lopes-Virella, MF; Pate, V; Thorpe, SR; Virella, G1
Ayala, V; Bellmunt, MJ; Dalfó, E; Ferrer, I; Pamplona, R; Portero-Otín, M; Prat, J1
Asghar, M; Lokhandwala, MF1
Durante, A; Monacelli, F; Odetti, P; Poggi, A; Storace, D; Traverso, N; Viviani, GL1
Arnason, JT; Beaulieu, LP; Bennett, SA; Cuerrier, A; Fraser, MH; Haddad, PS; Harris, CS; Johns, T; Martineau, LC; McIntyre, KL; Owen, PL1
Amiri, I; Goodarzi, MT; Karimi, J; Khodadadi, I; Tavilani, H1
Bidasee, KR; Kutty, S; Moore, CJ; Nagai, R; Shao, CH; Singh, J1
Atabak, S; Hedayati, M; Imani, H; Najafi, I; Rahmani, L; Tabibi, H1
Amouzegar, A; Azizi, F; Hedayati, M; Mirmiran, P; Sahranavard, S; Talaei, B1
Barrientos-Romero, JJ; Fajardo-Araujo, ME; Garay-Sevilla, ME; Quintanilla-García, CV; Reynaga-Ornelas, MG; Romero-Gutiérrez, G; Uribarri, J1
Ahmad, S; Alatar, AA; Faisal, M; Rehman, S1

Reviews

2 review(s) available for n(6)-carboxymethyllysine and malondialdehyde

ArticleYear
Glycation of collagen: the basis of its central role in the late complications of ageing and diabetes.
    The international journal of biochemistry & cell biology, 1996, Volume: 28, Issue:12

    Topics: Aging; Animals; Arginine; Collagen; Cross-Linking Reagents; Diabetes Complications; Diabetes Mellitus; Elastin; Glycation End Products, Advanced; Glycosylation; Humans; Imidazoles; Lysine; Maillard Reaction; Malondialdehyde; Norleucine; Pyrroles

1996
Lipoxidation products as biomarkers of oxidative damage to proteins during lipid peroxidation reactions.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1996, Volume: 11 Suppl 5

    Topics: Aldehydes; Arteriosclerosis; Biomarkers; Diabetes Mellitus; Glycation End Products, Advanced; Humans; Lipid Peroxidation; Lipoproteins, LDL; Lysine; Maillard Reaction; Malondialdehyde; Oxidative Stress; Proteins

1996

Trials

3 trial(s) available for n(6)-carboxymethyllysine and malondialdehyde

ArticleYear
Immunohistochemical evidence for an increased oxidative stress and carbonyl modification of proteins in diabetic glomerular lesions.
    Journal of the American Society of Nephrology : JASN, 1999, Volume: 10, Issue:4

    Topics: Adult; Biomarkers; Biopsy, Needle; Culture Techniques; Diabetic Nephropathies; Female; Glomerular Mesangium; Glomerulonephritis, IGA; Glycation End Products, Advanced; Humans; Immunohistochemistry; Kidney Function Tests; Lysine; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Protein Denaturation; Reference Values; Sensitivity and Specificity

1999
Effects of ginger on serum glucose, advanced glycation end products, and inflammation in peritoneal dialysis patients.
    Nutrition (Burbank, Los Angeles County, Calif.), 2015, Volume: 31, Issue:5

    Topics: Adult; Aged; Arginine; Blood Glucose; C-Reactive Protein; Dietary Supplements; Double-Blind Method; E-Selectin; Female; Glycation End Products, Advanced; Humans; Inflammation; Intercellular Adhesion Molecule-1; Kidney Failure, Chronic; Lysine; Male; Malondialdehyde; Middle Aged; Peritoneal Dialysis; Treatment Outcome; Vascular Cell Adhesion Molecule-1; Zingiber officinale

2015
Effects of Cinnamon Consumption on Glycemic Indicators, Advanced Glycation End Products, and Antioxidant Status in Type 2 Diabetic Patients.
    Nutrients, 2017, Sep-08, Volume: 9, Issue:9

    Topics: Aged; Antioxidants; Blood Glucose; Cinnamomum zeylanicum; Diabetes Mellitus, Type 2; Double-Blind Method; Glycated Hemoglobin; Glycation End Products, Advanced; Homeostasis; Humans; Insulin; Lysine; Malondialdehyde; Middle Aged

2017

Other Studies

24 other study(ies) available for n(6)-carboxymethyllysine and malondialdehyde

ArticleYear
Immunohistochemical colocalization of glycoxidation products and lipid peroxidation products in diabetic renal glomerular lesions. Implication for glycoxidative stress in the pathogenesis of diabetic nephropathy.
    The Journal of clinical investigation, 1997, Dec-15, Volume: 100, Issue:12

    Topics: Adolescent; Adult; Aged; Animals; Antibodies; Arginine; Collagen; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Glycation End Products, Advanced; Humans; Immunoenzyme Techniques; Kidney Glomerulus; Lipid Peroxidation; Lysine; Male; Malondialdehyde; Mice; Middle Aged; Nephrotic Syndrome; Norleucine; Pyrroles; Rabbits

1997
Glycoxidation in aortic collagen from STZ-induced diabetic rats and its relevance to vascular damage.
    Atherosclerosis, 1998, Volume: 136, Issue:2

    Topics: Aldehydes; Animals; Aorta; Collagen; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Glycosylation; Immunohistochemistry; Lipid Peroxidation; Lysine; Male; Malondialdehyde; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Streptozocin

1998
Autoxidation products of both carbohydrates and lipids are increased in uremic plasma: is there oxidative stress in uremia?
    Kidney international, 1998, Volume: 54, Issue:4

    Topics: Adult; Aged; Arginine; Carbohydrates; Case-Control Studies; Glycation End Products, Advanced; Humans; Lipid Peroxidation; Lipids; Lysine; Malondialdehyde; Middle Aged; Oxidation-Reduction; Oxidative Stress; Uremia

1998
Aromatic hydroxylation in animal models of diabetes mellitus.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1998, Volume: 12, Issue:14

    Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Type 1; Disease Models, Animal; Female; Fructosamine; Hydroxylation; Kidney; Lysine; Malondialdehyde; Mice; Rats; Rats, Inbred BB; Rats, Sprague-Dawley; Streptozocin; Tyrosine

1998
Increased carbonyl modification by lipids and carbohydrates in diabetic nephropathy.
    Kidney international. Supplement, 1999, Volume: 71

    Topics: Animals; Carbohydrate Metabolism; Cells, Cultured; Diabetic Nephropathies; Glycation End Products, Advanced; Humans; Immunohistochemistry; Kidney Glomerulus; Lipid Metabolism; Lipid Peroxidation; Lysine; Malondialdehyde; Oxidation-Reduction; Rats

1999
Thyroid status modulates glycoxidative and lipoxidative modification of tissue proteins.
    Free radical biology & medicine, 1999, Volume: 27, Issue:7-8

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Biomarkers; Deoxyguanosine; DNA Damage; Endopeptidases; Fatty Acids; Gas Chromatography-Mass Spectrometry; Glycation End Products, Advanced; Glycosylation; Hyperthyroidism; Hypothyroidism; Lipid Peroxidation; Liver; Lysine; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Thyroid Hormones

1999
Mechanism of the inhibitory effect of OPB-9195 [(+/-)-2-isopropylidenehydrazono-4-oxo-thiazolidin-5-yla cetanilide] on advanced glycation end product and advanced lipoxidation end product formation.
    Journal of the American Society of Nephrology : JASN, 2000, Volume: 11, Issue:9

    Topics: Aldehydes; Arachidonic Acid; Arginine; Deoxyglucose; Dialysis Solutions; Glycation End Products, Advanced; Glyoxal; Guanidines; Lipid Metabolism; Lysine; Malondialdehyde; Oxidation-Reduction; Peritoneal Dialysis; Prodrugs; Pyruvaldehyde; Thiadiazoles; Thiazolidines

2000
Glycoxidation and lipid peroxidation of low-density lipoprotein can synergistically enhance atherogenesis.
    Cardiovascular research, 2001, Feb-01, Volume: 49, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Arteriosclerosis; Chelating Agents; Copper; Edetic Acid; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Glucose; Guanidines; Humans; Immunohistochemistry; Lipid Peroxidation; Lipoproteins, LDL; Lysine; Male; Malondialdehyde; Middle Aged; Pentetic Acid; Receptors, Immunologic; Receptors, Scavenger

2001
Circulating advanced glycation end product levels in rats rapidly increase with acute renal failure.
    Kidney international. Supplement, 2001, Volume: 78

    Topics: Acute Kidney Injury; Animals; Antioxidants; Glutathione Peroxidase; Glycation End Products, Advanced; Lipid Peroxidation; Lipofuscin; Lysine; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Time Factors

2001
[Increased levels of circulating advanced glycation end products in a model of acute renal insufficiency in rats].
    Casopis lekaru ceskych, 2001, Jun-21, Volume: 140, Issue:12

    Topics: Acute Kidney Injury; Animals; Antioxidants; Creatinine; Glycation End Products, Advanced; Lipofuscin; Lysine; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar

2001
Aging increases Nepsilon-(carboxymethyl)lysine and caloric restriction decreases Nepsilon-(carboxyethyl)lysine and Nepsilon-(malondialdehyde)lysine in rat heart mitochondrial proteins.
    Free radical research, 2002, Volume: 36, Issue:1

    Topics: Aging; Animals; Enzyme-Linked Immunosorbent Assay; Fatty Acids; Food Deprivation; Gas Chromatography-Mass Spectrometry; Lysine; Male; Malondialdehyde; Mitochondria; Models, Statistical; Myocardium; Oxidative Stress; Phospholipids; Rats; Rats, Wistar; Reactive Oxygen Species; Time Factors

2002
Lipid peroxidation and advanced glycation end products in the brain in normal aging and in Alzheimer's disease.
    Acta neuropathologica, 2002, Volume: 104, Issue:2

    Topics: Adolescent; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Brain; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lipid Peroxidation; Lysine; Male; Malondialdehyde; Neuroglia; Neurons; Oxidative Stress

2002
Contribution of superoxide to reduced antioxidant activity of glycoxidative serum albumin.
    Heart and vessels, 2002, Volume: 17, Issue:1

    Topics: Antioxidants; Copper; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Free Radical Scavengers; Glucose; Glycation End Products, Advanced; Glycosylation; Humans; Lipid Peroxidation; Lipoproteins, LDL; Lysine; Malondialdehyde; Oxidants; Oxidation-Reduction; Oxidative Stress; Protein Binding; Serum Albumin; Serum Albumin, Human; Superoxides; Time Factors

2002
Effects of diabetes, insulin and antioxidants on NO synthase abundance and NO interaction with reactive oxygen species.
    Kidney international, 2003, Volume: 63, Issue:1

    Topics: Animals; Antioxidants; Blood Pressure; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Insulin; Lysine; Male; Malondialdehyde; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tyrosine

2003
Effects of ramipril in nondiabetic nephropathy: improved parameters of oxidatives stress and potential modulation of advanced glycation end products.
    Journal of human hypertension, 2003, Volume: 17, Issue:4

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Biomarkers; Blood Glucose; Blood Pressure; Creatinine; Cystatin C; Cystatins; Diabetic Nephropathies; Female; Glomerulonephritis; Glycation End Products, Advanced; Homocysteine; Humans; Lipofuscin; Lysine; Male; Malondialdehyde; Middle Aged; Nephritis, Interstitial; Oxidative Stress; Polycystic Kidney Diseases; Ramipril; Severity of Illness Index; Statistics as Topic; Treatment Outcome

2003
Development of capture assays for different modifications of human low-density lipoprotein.
    Clinical and diagnostic laboratory immunology, 2005, Volume: 12, Issue:1

    Topics: Animals; Antigen-Antibody Complex; Copper; Enzyme-Linked Immunosorbent Assay; Humans; Lipoproteins, LDL; Lysine; Malondialdehyde; Rabbits; Reproducibility of Results; Sensitivity and Specificity

2005
Proteins in human brain cortex are modified by oxidation, glycoxidation, and lipoxidation. Effects of Alzheimer disease and identification of lipoxidation targets.
    The Journal of biological chemistry, 2005, Jun-03, Volume: 280, Issue:22

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Blotting, Western; Brain; Carbon; Cerebral Cortex; Databases as Topic; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Fatty Acids; Fatty Acids, Unsaturated; Female; Glial Fibrillary Acidic Protein; Glycation End Products, Advanced; Glycolysis; Humans; Lipid Metabolism; Lipid Peroxidation; Lysine; Male; Malondialdehyde; NADH Dehydrogenase; Oxygen; Phenylhydrazines; Proteins; Silver Staining; Ubiquinone

2005
Antioxidant tempol lowers age-related increases in insulin resistance in Fischer 344 rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2006, Volume: 28, Issue:5

    Topics: Age Factors; Aging; Animals; Antioxidants; Biomarkers; Blood Glucose; Blood Proteins; Cyclic N-Oxides; Dietary Supplements; Homeostasis; Insulin; Insulin Resistance; Kidney Tubules, Proximal; Lysine; Male; Malondialdehyde; Models, Animal; Oxidative Stress; Rats; Rats, Inbred F344; Spin Labels; Triglycerides

2006
Effects of valsartan therapy on protein glycoxidation.
    Metabolism: clinical and experimental, 2006, Volume: 55, Issue:12

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Arginine; Dinoprost; Female; Glycation End Products, Advanced; Glycosylation; Humans; Hypertension; Lysine; Male; Malondialdehyde; Middle Aged; Oxidation-Reduction; Proteins; Tetrazoles; Valine; Valsartan

2006
Inhibition of advanced glycation end product formation by medicinal plant extracts correlates with phenolic metabolites and antioxidant activity.
    Planta medica, 2011, Volume: 77, Issue:2

    Topics: Antioxidants; Canada; Free Radical Scavengers; Glycation End Products, Advanced; Lysine; Malondialdehyde; Oxidation-Reduction; Phenols; Plant Extracts; Plants, Medicinal; Time Factors

2011
Relationship between advanced glycation end products and increased lipid peroxidation in semen of diabetic men.
    Diabetes research and clinical practice, 2011, Volume: 91, Issue:1

    Topics: Adult; Antioxidants; Blood Glucose; Diabetes Complications; Diabetes Mellitus; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Infertility, Male; Lipid Peroxidation; Lysine; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Semen; Spermatozoa; Thiobarbituric Acid Reactive Substances; Young Adult

2011
Malondialdehyde and 4-hydroxynonenal adducts are not formed on cardiac ryanodine receptor (RyR2) and sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA2) in diabetes.
    Molecular and cellular biochemistry, 2013, Volume: 376, Issue:1-2

    Topics: Aldehydes; Animals; Arginine; Calcium; Cyclic N-Oxides; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Echocardiography; Guanidines; Lysine; Male; Malondialdehyde; Myocytes, Cardiac; Norleucine; Protein Carbonylation; Pyridoxamine; Pyrroles; Rats; Rats, Sprague-Dawley; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Spin Labels

2013
Changes in circulating levels of carboxymethyllysine, soluble receptor for advanced glycation end products (sRAGE), and inflammation markers in women during normal pregnancy.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2019, Volume: 32, Issue:24

    Topics: Adolescent; Adult; Biomarkers; C-Reactive Protein; Female; Humans; Infant, Newborn; Insulin; Longitudinal Studies; Lysine; Malondialdehyde; Pregnancy; Receptor for Advanced Glycation End Products; Tumor Necrosis Factor-alpha; Young Adult

2019
Physico-chemical Changes Induced in the Serum Proteins Immunoglobulin G and Fibrinogen Mediated by Methylglyoxal.
    Current protein & peptide science, 2020, Volume: 21, Issue:9

    Topics: Arginine; Benzothiazoles; Fibrinogen; Furaldehyde; Glycation End Products, Advanced; Glycosylation; Humans; Immunoglobulin G; Kinetics; Lysine; Malondialdehyde; Oxidation-Reduction; Protein Carbonylation; Pyruvaldehyde; Solutions; Spectrometry, Fluorescence

2020