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n(6)-benzyladenosine and adenosine

n(6)-benzyladenosine has been researched along with adenosine in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19904 (19.05)18.7374
1990's5 (23.81)18.2507
2000's6 (28.57)29.6817
2010's6 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bey, P; Demeter, DA; Dudley, MW; Lentz, NL; Meng, EC; Ogden, AM; Peet, NP; Weintraub, HJ1
Bruns, RF; Trivedi, BK1
Daly, JW1
Cristalli, G; Esker, JL; Jacobson, KA; Ji, XD; Melman, N; Olah, ME; Schneller, SW; Secrist, JA; Siddiqi, SM; Tiwari, KN1
Aronov, AM; Gelb, MH; Hol, WG; Verlinde, CL1
Aronov, AM; Gelb, MH1
Bressi, JC; Buckner, FS; Choe, J; Gelb, MH; Hol, WG; Hough, MT; Van Voorhis, WC; Verlinde, CL1
Konings, RN; Luiten, RG; Schoenmakers, JG1
Froehler, BC; Matteucci, MD1
Brezinová, A; Holík, J; Vlasáková, V1
Kuglík, P; Mlejnek, P1
Mlejnek, P2
Al Safarjalani, ON; Chu, CK; el Kouni, MH; Kim, YA; Naguib, FN; Rais, RH; Sharon, A1
Chakrabarty, K; Dolezal, K; Hauserová, E; Holub, J; Krystof, V; Novák, O; Popa, I; Spíchal, L; Strnad, M; Voller, J1
Arita, M; Shimizu, H; Wakita, T1
Béres, T; Dolezal, K; Dzubák, P; Hajdúch, M; Krystof, V; Lenobel, R; Niemann, P; Spíchal, L; Strnad, M; Voller, J; Zatloukal, M1
Dolezel, P; Koudelkova, P; Mlejnek, P1
Baldoli, E; Casati, S; Ciuffreda, P; Lopez, E; Maier, JA; Ottria, R1
Casati, S; Castiglioni, S; Ciuffreda, P; Maier, JA; Ottria, R1
Chizhov, AO; Drenichev, MS; Kurochkin, NN; Leyssen, P; Mikhailov, SN; Neyts, J; Oslovsky, VE; Pannecouque, C; Sun, L; Tararov, VI; Tijsma, A1

Reviews

1 review(s) available for n(6)-benzyladenosine and adenosine

ArticleYear
Adenosine receptors: targets for future drugs.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:3

    Topics: Adenosine; Adenosine Triphosphate; Animals; Humans; Ligands; Receptors, Cell Surface; Receptors, Purinergic; Structure-Activity Relationship; Xanthines

1982

Other Studies

20 other study(ies) available for n(6)-benzyladenosine and adenosine

ArticleYear
A novel synthesis of xanthines: support for a new binding mode for xanthines with respect to adenosine at adenosine receptors.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:12

    Topics: Adenosine; Animals; Dogs; Humans; Molecular Conformation; Molecular Structure; Protein Binding; Rats; Receptors, Purinergic; Structure-Activity Relationship; Theophylline; Xanthines

1990
C2,N6-disubstituted adenosines: synthesis and structure-activity relationships.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:8

    Topics: Adenosine; Animals; Binding, Competitive; Chemical Phenomena; Chemistry; Rats; Receptors, Purinergic; Structure-Activity Relationship

1989
Search for new purine- and ribose-modified adenosine analogues as selective agonists and antagonists at adenosine receptors.
    Journal of medicinal chemistry, 1995, Mar-31, Volume: 38, Issue:7

    Topics: Adenosine; Animals; Cell Membrane; CHO Cells; Corpus Striatum; Cricetinae; In Vitro Techniques; Magnetic Resonance Spectroscopy; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Radioligand Assay; Rats; Recombinant Proteins; Ribose; Structure-Activity Relationship

1995
Selective tight binding inhibitors of trypanosomal glyceraldehyde-3-phosphate dehydrogenase via structure-based drug design.
    Journal of medicinal chemistry, 1998, Nov-19, Volume: 41, Issue:24

    Topics: Adenosine; Animals; Binding Sites; Crystallography, X-Ray; Drug Design; Enzyme Inhibitors; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Leishmania mexicana; Models, Molecular; NAD; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei

1998
Synthesis and structure-activity relationships of adenosine analogs as inhibitors of trypanosomal glyceraldehyde-3-phosphate dehydrogenase. Modifications at positions 5' and 8.
    Bioorganic & medicinal chemistry letters, 1998, Dec-15, Volume: 8, Issue:24

    Topics: Adenosine; Animals; Enzyme Inhibitors; Glyceraldehyde-3-Phosphate Dehydrogenases; Leishmania mexicana; Magnetic Resonance Spectroscopy; Molecular Structure; Structure-Activity Relationship; Trypanosoma

1998
Adenosine analogues as inhibitors of Trypanosoma brucei phosphoglycerate kinase: elucidation of a novel binding mode for a 2-amino-N(6)-substituted adenosine.
    Journal of medicinal chemistry, 2000, Nov-02, Volume: 43, Issue:22

    Topics: Adenosine; Animals; Combinatorial Chemistry Techniques; Crystallography, X-Ray; Enzyme Inhibitors; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycerolphosphate Dehydrogenase; Models, Molecular; Molecular Conformation; Phosphoglycerate Kinase; Protein Binding; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma cruzi

2000
The major coat protein gene of the filamentous Pseudomonas aeruginosa phage Pf3: absence of an N-terminal leader signal sequence.
    Nucleic acids research, 1983, Nov-25, Volume: 11, Issue:22

    Topics: Adenosine; Amino Acid Sequence; Bacteriophages; Base Sequence; Capsid; Cloning, Molecular; DNA Replication; DNA Restriction Enzymes; DNA, Viral; Peptides; Protein Sorting Signals; Pseudomonas aeruginosa; Virus Replication

1983
Dialkylformamidines: depurination resistant N6-protecting group for deoxyadenosine.
    Nucleic acids research, 1983, Nov-25, Volume: 11, Issue:22

    Topics: Adenosine; Amidines; Deoxyadenosines; Formamides; Indicators and Reagents; Kinetics; Oligodeoxyribonucleotides; Oligonucleotides; Structure-Activity Relationship

1983
Study of cytokinin metabolism using HPLC with radioisotope detection.
    Journal of pharmaceutical and biomedical analysis, 1998, Volume: 17, Issue:1

    Topics: Adenine; Adenosine; Benzyl Compounds; Chromatography, High Pressure Liquid; Kinetin; Purines; Radiometry; Reproducibility of Results; Triticum; Tritium

1998
Induction of apoptosis in HL-60 cells by N(6)-benzyladenosine.
    Journal of cellular biochemistry, 2000, Volume: 77, Issue:1

    Topics: Adenosine; Apoptosis; Chromatin; DNA Fragmentation; HL-60 Cells; Humans; Phosphorylation; Receptors, Purinergic P1; Signal Transduction

2000
Caspase inhibition and N6-benzyladenosine-induced apoptosis in HL-60 cells.
    Journal of cellular biochemistry, 2001, Volume: 83, Issue:4

    Topics: Adenosine; Amino Acid Chloromethyl Ketones; Apoptosis; Caspase 3; Caspase 9; Caspase Inhibitors; Caspases; Cell Membrane; Cell Nucleus; Chromatin; Cysteine Proteinase Inhibitors; HL-60 Cells; Humans; Oligopeptides

2001
Synthesis, biological evaluation and molecular modeling studies of N6-benzyladenosine analogues as potential anti-toxoplasma agents.
    Biochemical pharmacology, 2007, May-15, Volume: 73, Issue:10

    Topics: Adenosine; Adenosine Kinase; Animals; Antiprotozoal Agents; Models, Molecular; Molecular Conformation; Parasitic Sensitivity Tests; Structure-Activity Relationship; Toxoplasma

2007
Preparation, biological activity and endogenous occurrence of N6-benzyladenosines.
    Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11

    Topics: Adenosine; Animals; Antineoplastic Agents; Arabidopsis Proteins; Biological Assay; Cells, Cultured; Cytokinins; Fibroblasts; Histidine Kinase; Mice; NIH 3T3 Cells; Plant Cells; Plants; Protein Kinases; Receptors, Cell Surface

2007
Characterization of pharmacologically active compounds that inhibit poliovirus and enterovirus 71 infectivity.
    The Journal of general virology, 2008, Volume: 89, Issue:Pt 10

    Topics: Adenosine; Animals; Antiviral Agents; Benzenesulfonates; Capsid Proteins; Cell Line; Drug Resistance, Viral; Enterovirus; Humans; Indoles; Luciferases; Mice; Microbial Sensitivity Tests; Mutation; Phenols; Poliovirus; Replicon; RNA Interference; Virus Replication

2008
Anticancer activity of natural cytokinins: a structure-activity relationship study.
    Phytochemistry, 2010, Volume: 71, Issue:11-12

    Topics: Adenosine; Antineoplastic Agents; Cytokinins; Drug Screening Assays, Antitumor; Genes, p53; Humans; Inhibitory Concentration 50; Isopentenyladenosine; Kinetin; Molecular Structure; National Cancer Institute (U.S.); Plant Growth Regulators; Stereoisomerism; Structure-Activity Relationship; United States

2010
Halogenation of N⁶-benzyladenosine decreases its cytotoxicity in human leukemia cells.
    Toxicology in vitro : an international journal published in association with BIBRA, 2010, Volume: 24, Issue:8

    Topics: Adenosine; Cell Proliferation; Cell Survival; Cytotoxins; Halogenation; Humans; U937 Cells

2010
Effects of cytokinins, cytokinin ribosides and their analogs on the viability of normal and neoplastic human cells.
    Anticancer research, 2011, Volume: 31, Issue:10

    Topics: Adenosine; Cell Line, Tumor; Cell Survival; Cisplatin; Cytokinins; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Isopentenyladenosine; Neoplasms; Neutral Red; Ribonucleosides; Tumor Stem Cell Assay; Zeatin

2011
N6-isopentenyladenosine and its analogue N6-benzyladenosine induce cell cycle arrest and apoptosis in bladder carcinoma T24 cells.
    Anti-cancer agents in medicinal chemistry, 2013, Volume: 13, Issue:4

    Topics: Adenosine; Antineoplastic Agents; Apoptosis; Cell Cycle; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Isopentenyladenosine; Molecular Structure; Structure-Activity Relationship; Tumor Cells, Cultured; Urinary Bladder Neoplasms

2013
Cytokinin-induced cell death is associated with elevated expression of alternative oxidase in tobacco BY-2 cells.
    Protoplasma, 2013, Volume: 250, Issue:5

    Topics: Adenosine; Benzyl Compounds; Cell Death; Cells, Cultured; Genetic Engineering; Kinetin; Mitochondria; Nicotiana; Oxidoreductases; Plant Proteins; Plants, Genetically Modified; Purines; Reactive Oxygen Species; RNA, Messenger

2013
Modification of the length and structure of the linker of N(6)-benzyladenosine modulates its selective antiviral activity against enterovirus 71.
    European journal of medicinal chemistry, 2016, Mar-23, Volume: 111

    Topics: Adenosine; Antiviral Agents; Dose-Response Relationship, Drug; Enterovirus A, Human; Humans; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship

2016