n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine has been researched along with phenylisopropyladenosine in 9 studies
| Studies (n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine) | Trials (n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine) | Recent Studies (post-2010) (n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine) | Studies (phenylisopropyladenosine) | Trials (phenylisopropyladenosine) | Recent Studies (post-2010) (phenylisopropyladenosine) |
|---|---|---|---|---|---|
| 214 | 5 | 58 | 63 | 0 | 10 |
| Protein | Taxonomy | n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine (IC50) | phenylisopropyladenosine (IC50) |
|---|---|---|---|
| high affinity choline transporter 1 isoform a | Homo sapiens (human) | 1.8613 | |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | 0.0294 | |
| Adenosine receptor A3 | Rattus norvegicus (Norway rat) | 0.0497 | |
| Adenosine receptor A2b | Rattus norvegicus (Norway rat) | 0.2898 | |
| Adenosine receptor A1 | Homo sapiens (human) | 0.83 | |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | 0.2898 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jacobson, KA; Kim, J; Schöneberg, T; van Rhee, AM; Wess, J | 1 |
| Fredholm, BB; Hegler, J; Hessling, J; Klotz, KN; Kull, B; Lohse, MJ; Owman, C | 1 |
| Cappellacci, L; Franchetti, P; Grifantini, M; Lucacchini, A; Marchetti, S; Martini, C; Mazzoni, MR; Trincavelli, L | 1 |
| Figler, H; Jin, X; Linden, J; Robeva, AS; Thai, T | 1 |
| Baraldi, PG; Borea, PA; Cacciari, B; Gessi, S; Klotz, KN; Leung, E; Merighi, S; Romagnoli, R; Spalluto, G; Varani, K | 1 |
| Barak, D; Biadatti, T; Chen, W; Gao, ZG; Jacobson, KA; Johnson, CR; Kim, SG; Kim, SK; Lee, K | 1 |
| Carmody, LC; Dandapani, S; Donckele, E; Feng, Y; Fernandez, C; Germain, AR; Gupta, PB; Lander, ES; Morgan, B; Munoz, B; Nag, PP; Palmer, M; Perez, JR; Schreiber, SL; Verplank, L | 1 |
| Donegan, RK; Lieberman, RL | 1 |
| Cheng, J; McCorvy, JD; Tan, L; Yan, W | 1 |
2 review(s) available for n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine and phenylisopropyladenosine
| Article | Year |
|---|---|
Discovery of Molecular Therapeutics for Glaucoma: Challenges, Successes, and Promising Directions.
Topics: Adrenergic Agonists; Adrenergic Antagonists; Adrenergic beta-Antagonists; Animals; Drug Discovery; Glaucoma; Humans; Ligands; Protein Kinase Inhibitors; rho-Associated Kinases; Sympathomimetics | 2016 |
Biased Ligands of G Protein-Coupled Receptors (GPCRs): Structure-Functional Selectivity Relationships (SFSRs) and Therapeutic Potential.
Topics: Animals; Drug Discovery; Humans; Ligands; Receptors, G-Protein-Coupled; Signal Transduction; Structure-Activity Relationship | 2018 |
7 other study(ies) available for n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine and phenylisopropyladenosine
| Article | Year |
|---|---|
Site-directed mutagenesis identifies residues involved in ligand recognition in the human A2a adenosine receptor.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Histidine; Ligands; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Receptors, Purinergic P1; Structure-Activity Relationship | 1995 |
Comparative pharmacology of human adenosine receptor subtypes - characterization of stably transfected receptors in CHO cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Base Composition; Binding, Competitive; CHO Cells; Cricetinae; Guanylate Cyclase; Humans; Phenethylamines; Phenylisopropyladenosine; Receptors, Purinergic P1; Stereoisomerism; Structure-Activity Relationship; Transfection; Xanthines | 1998 |
2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Animals; Brain; Cattle; Enzyme Inhibitors; In Vitro Techniques; Male; Membranes; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Testis | 1998 |
Characterization of human A(2B) adenosine receptors: radioligand binding, western blotting, and coupling to G(q) in human embryonic kidney 293 cells and HMC-1 mast cells.
Topics: Animals; Anti-Asthmatic Agents; Blotting, Western; Calcium; Cell Degranulation; Cells, Cultured; CHO Cells; Cricetinae; Cyclic AMP; GTP-Binding Proteins; Humans; Kidney; Mast Cells; Purinergic P1 Receptor Agonists; Radioligand Assay; Receptor, Adenosine A2B; Receptors, Purinergic P1; Theophylline; Type C Phospholipases; Xanthines | 1999 |
[(3)H]MRE 3008F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Animals; Binding, Competitive; CHO Cells; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Phenylurea Compounds; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Receptor, Adenosine A3; Receptors, Purinergic P1; Triazoles; Tritium | 2000 |
Structural determinants of A(3) adenosine receptor activation: nucleoside ligands at the agonist/antagonist boundary.
Topics: Adenosine; Animals; Binding, Competitive; CHO Cells; Cricetinae; Epoxy Compounds; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Ligands; Models, Molecular; Mutation; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Receptor, Adenosine A3; Receptors, Purinergic P1; Ribose; Spiro Compounds; Stereoisomerism; Structure-Activity Relationship | 2002 |
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.
Topics: Amides; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Neoplastic Stem Cells; Small Molecule Libraries; Structure-Activity Relationship | 2013 |