n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine and n-(4-methylthiazol-2-yl)-2-(6-phenylpyridazin-3-ylthio)acetamide

n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine has been researched along with n-(4-methylthiazol-2-yl)-2-(6-phenylpyridazin-3-ylthio)acetamide in 1 studies

Compound Research Comparison

Studies (n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine)	Trials (n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine)	Recent Studies (post-2010) (n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine)	Studies (n-(4-methylthiazol-2-yl)-2-(6-phenylpyridazin-3-ylthio)acetamide)	Trials (n-(4-methylthiazol-2-yl)-2-(6-phenylpyridazin-3-ylthio)acetamide)	Recent Studies (post-2010) (n-(4-methylthiazol-2-yl)-2-(6-phenylpyridazin-3-ylthio)acetamide)
214	5	58	20	0	14

Protein Interaction Comparison

Protein	Taxonomy	n-(4-methylthiazol-2-yl)-2-(6-phenylpyridazin-3-ylthio)acetamide (IC50)
electroneutral potassium-chloride cotransporter KCC2	Homo sapiens (human)	0.56
solute carrier family 12 member 2 isoform 1	Homo sapiens (human)	0.56
Cytochrome P450 1A2	Homo sapiens (human)	0.568
Cytochrome P450 2C9	Homo sapiens (human)	0.568
Solute carrier family 12 member 5	Homo sapiens (human)	0.568

Research

Studies (1)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Castonguay, A; Chen, Z; Cottet, M; De Koninck, Y; Doyle, T; Egan, TM; Ford, A; Jacobson, KA; Little, JW; Salvemini, D; Symons-Liguori, AM; Tosh, DK; Vanderah, TW	1

Other Studies

1 other study(ies) available for n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine and n-(4-methylthiazol-2-yl)-2-(6-phenylpyridazin-3-ylthio)acetamide

Article	Year
Engagement of the GABA to KCC2 signaling pathway contributes to the analgesic effects of A3AR agonists in neuropathic pain. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, 04-15, Volume: 35, Issue:15 Topics: Adenosine; Adenosine A3 Receptor Agonists; Analgesics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; HEK293 Cells; Humans; Hyperalgesia; K Cl- Cotransporters; Male; Mice; Pain Threshold; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sciatica; Signal Transduction; Spinal Nerve Roots; Symporters; Thiazoles; Thioglycolates	2015

Article

Year

Engagement of the GABA to KCC2 signaling pathway contributes to the analgesic effects of A3AR agonists in neuropathic pain.

The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, 04-15, Volume: 35, Issue:15

Topics: Adenosine; Adenosine A3 Receptor Agonists; Analgesics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; HEK293 Cells; Humans; Hyperalgesia; K Cl- Cotransporters; Male; Mice; Pain Threshold; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sciatica; Signal Transduction; Spinal Nerve Roots; Symporters; Thiazoles; Thioglycolates

2015