Compounds > n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine

Page last updated: 2024-09-03

n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine and mrs 1220

n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine has been researched along with mrs 1220 in 8 studies

Compound Research Comparison

Studies (n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine)	Trials (n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine)	Recent Studies (post-2010) (n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine)	Studies (mrs 1220)	Trials (mrs 1220)	Recent Studies (post-2010) (mrs 1220)
214	5	58	54	1	13

Protein Interaction Comparison

Protein	Taxonomy	n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine (IC50)	mrs 1220 (IC50)
Adenosine receptor A3	Homo sapiens (human)		0.0036
Adenosine receptor A1	Homo sapiens (human)		0.0479

Research

Studies (8)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	5 (62.50)	29.6817
2010's	2 (25.00)	24.3611
2020's	1 (12.50)	2.80

Authors

Authors	Studies
Barak, D; Biadatti, T; Chen, W; Gao, ZG; Jacobson, KA; Johnson, CR; Kim, SG; Kim, SK; Lee, K	1
Baraldi, PG; Borea, PA; Preti, D; Varani, K	1
Federico, S; Jacobson, KA; Jayasekara, PS; Kozma, E; Moro, S; Paoletta, S; Spalluto, G; Squarcialupi, L	1
Campbell, RG; Chen, E; Gao, ZG; Jacobson, KA; Liston, TE; Poe, RB; Salmaso, V; Suresh, RR	1
Abbracchio, MP; Barbieri, D; Brambilla, R; Cattabeni, F; Ceruti, S; Franceschi, C; Jacobson, KA; Kim, YC; Klotz, KN; Lohse, MJ	1
Ezeamuzie, CI; Philips, E	1
Baharav, E; Bar-Yehuda, S; Fishman, P; Halpren, M; Madi, L; Ochaion, A; Rath-Wolfson, L; Silberman, D; Weinberger, A	1
Broadley, KJ; Clark, JH; James, S; Kidd, EJ; Martin, TJ; Yates, L	1

Reviews

2 review(s) available for n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine and mrs 1220

Article	Year
Medicinal chemistry of A₃ adenosine receptor modulators: pharmacological activities and therapeutic implications. Journal of medicinal chemistry, 2012, Jun-28, Volume: 55, Issue:12 Topics: Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Animals; Chemistry, Pharmaceutical; Disease; Humans; Ligands; Receptor, Adenosine A3	2012
Fluorescent ligands for adenosine receptors. Bioorganic & medicinal chemistry letters, 2013, Jan-01, Volume: 23, Issue:1 Topics: Boron Compounds; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Ligands; Protein Binding; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1	2013

Other Studies

6 other study(ies) available for n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine and mrs 1220

Article	Year
Structural determinants of A(3) adenosine receptor activation: nucleoside ligands at the agonist/antagonist boundary. Journal of medicinal chemistry, 2002, Sep-26, Volume: 45, Issue:20 Topics: Adenosine; Animals; Binding, Competitive; CHO Cells; Cricetinae; Epoxy Compounds; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Ligands; Models, Molecular; Mutation; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Receptor, Adenosine A3; Receptors, Purinergic P1; Ribose; Spiro Compounds; Stereoisomerism; Structure-Activity Relationship	2002
Selective A ACS medicinal chemistry letters, 2022, Apr-14, Volume: 13, Issue:4 Topics:	2022
Activation of the A3 adenosine receptor affects cell cycle progression and cell growth. Naunyn-Schmiedeberg's archives of pharmacology, 2000, Volume: 361, Issue:3 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Analysis of Variance; Animals; Antineoplastic Agents; Cell Cycle; Cell Line; Cell Membrane; Cell Survival; CHO Cells; Cricetinae; Dihydropyridines; Flow Cytometry; Humans; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A3; Receptors, Purinergic P1; Transfection; Triazoles	2000
Positive coupling of atypical adenosine A3 receptors on human eosinophils to adenylyl cyclase. Biochemical and biophysical research communications, 2003, Jan-17, Volume: 300, Issue:3 Topics: Adenosine; Adenylyl Cyclases; Adult; Cell Degranulation; Cyclic AMP; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Eosinophils; Histamine; Humans; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Triazoles	2003
Antiinflammatory effect of A3 adenosine receptor agonists in murine autoimmune arthritis models. The Journal of rheumatology, 2005, Volume: 32, Issue:3 Topics: Adenosine; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Collagen; Dose-Response Relationship, Drug; Female; Joints; Lymph Nodes; Male; Mice; Mice, Inbred DBA; Quinazolines; Rats; Receptor, Adenosine A3; Spleen; Triazoles; Tumor Necrosis Factor-alpha	2005
Radioligand binding and functional responses of ligands for human recombinant adenosine A(3) receptors. Autonomic & autacoid pharmacology, 2006, Volume: 26, Issue:2 Topics: Adenosine; Animals; Binding, Competitive; CHO Cells; Cricetinae; Cyclic AMP; Guanosine 5'-O-(3-Thiotriphosphate); Iodine Radioisotopes; Ligands; Magnesium Chloride; Quinazolines; Radioligand Assay; Receptor, Adenosine A3; Recombinant Proteins; Transfection; Triazoles	2006