Compounds > n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine

Page last updated: 2024-09-03

n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine and mre 3008-f20

n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine has been researched along with mre 3008-f20 in 6 studies

Compound Research Comparison

Studies (n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine)	Trials (n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine)	Recent Studies (post-2010) (n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine)	Studies (mre 3008-f20)	Trials (mre 3008-f20)	Recent Studies (post-2010) (mre 3008-f20)
214	5	58	27	0	8

Protein Interaction Comparison

Protein	Taxonomy	n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine (IC50)	mre 3008-f20 (IC50)
Adenosine receptor A3	Homo sapiens (human)		0.0048

Research

Studies (6)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (66.67)	29.6817
2010's	1 (16.67)	24.3611
2020's	1 (16.67)	2.80

Authors

Authors	Studies
Baraldi, PG; Borea, PA; Cacciari, B; Gessi, S; Klotz, KN; Leung, E; Merighi, S; Romagnoli, R; Spalluto, G; Varani, K	1
Gao, ZG; Jacobson, KA	1
Ahn, S; Cheong, JH; Jacobson, KA; Jeong, LS; Jin, SH; Kim, G; Kim, HJ; Kim, J; Lee, E; Lee, M; Noh, M; Yu, J	1
Campbell, RG; Chen, E; Gao, ZG; Jacobson, KA; Liston, TE; Poe, RB; Salmaso, V; Suresh, RR	1
Baraldi, PG; Borea, PA; Cattabriga, E; Gessi, S; Iannotta, V; Leung, E; Merighi, S; Varani, K	1
Baraldi, PG; Borea, PA; Gessi, S; Klotz, KN; Leung, E; Merighi, S; Varani, K	1

Reviews

1 review(s) available for n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine and mre 3008-f20

Article	Year
Adenosine receptors as therapeutic targets. Nature reviews. Drug discovery, 2006, Volume: 5, Issue:3 Topics: Animals; Disease; Drug Therapy; Humans; Ligands; Molecular Structure; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Signal Transduction; Structure-Activity Relationship	2006

Other Studies

5 other study(ies) available for n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine and mre 3008-f20

Article	Year
[(3)H]MRE 3008F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors. Molecular pharmacology, 2000, Volume: 57, Issue:5 Topics: Adenosine; Adenylyl Cyclase Inhibitors; Animals; Binding, Competitive; CHO Cells; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Phenylurea Compounds; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Receptor, Adenosine A3; Receptors, Purinergic P1; Triazoles; Tritium	2000
Polypharmacology of N Journal of medicinal chemistry, 2017, 09-14, Volume: 60, Issue:17 Topics: Adenosine; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Adiponectin; Animals; Cell Line; Diabetes Mellitus, Experimental; Humans; Hypoglycemic Agents; Insulin Resistance; Ligands; Male; Mice; Mice, Inbred C57BL; Polypharmacology; PPAR delta; PPAR gamma; Receptor, Adenosine A3	2017
Selective A ACS medicinal chemistry letters, 2022, Apr-14, Volume: 13, Issue:4 Topics:	2022
A(3) adenosine receptors in human neutrophils and promyelocytic HL60 cells: a pharmacological and biochemical study. Molecular pharmacology, 2002, Volume: 61, Issue:2 Topics: Adenosine; Binding, Competitive; Biological Transport; Calcium; Cyclic AMP; Gene Expression; Granulocytes; HL-60 Cells; Humans; Neutrophils; Phenylurea Compounds; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A3; Receptors, Purinergic P1; Superoxides; Triazoles	2002
Binding thermodynamics at the human A(3) adenosine receptor. Biochemical pharmacology, 2002, Jan-15, Volume: 63, Issue:2 Topics: Adenosine; Animals; Cells, Cultured; CHO Cells; Cricetinae; Humans; Kinetics; Phenylurea Compounds; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A3; Receptors, Purinergic P1; Thermodynamics; Transfection; Triazoles	2002