Compounds > n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine

Page last updated: 2024-09-03

n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine and lj 529

n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine has been researched along with lj 529 in 5 studies

Compound Research Comparison

Studies (n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine)	Trials (n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine)	Recent Studies (post-2010) (n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine)	Studies (lj 529)	Trials (lj 529)	Recent Studies (post-2010) (lj 529)
214	5	58	12	0	3

Protein Interaction Comparison

Protein	Taxonomy	n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine (IC50)	lj 529 (IC50)
Adenosine receptor A3	Homo sapiens (human)		0.0006

Research

Studies (5)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (60.00)	29.6817
2010's	1 (20.00)	24.3611
2020's	1 (20.00)	2.80

Authors

Authors	Studies
Chun, MW; Gao, ZG; Gunaga, P; Jacobson, KA; Jeong, LS; Jin, DZ; Kim, HO; Kim, YC; Melman, N; Moon, HR; Shin, DH	1
Choe, SA; Choi, WJ; Gao, ZG; Hou, X; Jacobson, KA; Jeong, LS; Kim, HO; Klutz, AM; Lee, HW; Lee, SK; Moon, HR; Pal, S; Tosh, DK	1
Chinn, M; Choi, WJ; Gao, ZG; Jacobson, KA; Jeong, LS; Jung, YH; Kim, HO; Lee, HW; Moon, HR; Patel, A	1
Ahn, S; Cheong, JH; Jacobson, KA; Jeong, LS; Jin, SH; Kim, G; Kim, HJ; Kim, J; Lee, E; Lee, M; Noh, M; Yu, J	1
Ahn, S; An, S; Choi, H; Jeong, LS; Ko, H; Noh, M; Pyo, JJ; Shin, JC; Yu, J	1

Other Studies

5 other study(ies) available for n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine and lj 529

Article	Year
N6-substituted D-4'-thioadenosine-5'-methyluronamides: potent and selective agonists at the human A3 adenosine receptor. Journal of medicinal chemistry, 2003, Aug-28, Volume: 46, Issue:18 Topics: Adenosine; Animals; Cerebral Cortex; CHO Cells; Corpus Striatum; Cricetinae; Humans; Ligands; Purinergic P1 Receptor Agonists; Radioligand Assay; Rats; Receptor, Adenosine A3; Structure-Activity Relationship; Thionucleosides	2003
Structure-activity relationships of truncated D- and l-4'-thioadenosine derivatives as species-independent A3 adenosine receptor antagonists. Journal of medicinal chemistry, 2008, Oct-23, Volume: 51, Issue:20 Topics: Adenosine; Adenosine A3 Receptor Antagonists; Animals; Humans; Molecular Structure; Rats; Receptor, Adenosine A3; Structure-Activity Relationship; Thionucleosides	2008
Design and synthesis of N(6)-substituted-4'-thioadenosine-5'-uronamides as potent and selective human A(3) adenosine receptor agonists. Bioorganic & medicinal chemistry, 2009, Dec-01, Volume: 17, Issue:23 Topics: Adenosine A3 Receptor Agonists; Amides; Animals; CHO Cells; Cricetinae; Cricetulus; Humans; Kinetics; Magnetic Resonance Spectroscopy; Radioligand Assay; Spectrometry, Mass, Fast Atom Bombardment; Thionucleosides	2009
Polypharmacology of N Journal of medicinal chemistry, 2017, 09-14, Volume: 60, Issue:17 Topics: Adenosine; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Adiponectin; Animals; Cell Line; Diabetes Mellitus, Experimental; Humans; Hypoglycemic Agents; Insulin Resistance; Ligands; Male; Mice; Mice, Inbred C57BL; Polypharmacology; PPAR delta; PPAR gamma; Receptor, Adenosine A3	2017
Selenium bioisosteric replacement of adenosine derivatives promoting adiponectin secretion increases the binding affinity to peroxisome proliferator-activated receptor δ. Bioorganic & medicinal chemistry, 2020, 01-01, Volume: 28, Issue:1 Topics: Adenosine; Adiponectin; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Mesenchymal Stem Cells; Molecular Docking Simulation; Molecular Structure; PPAR delta; Selenium; Structure-Activity Relationship	2020