Compounds > n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine
Page last updated: 2024-09-03

n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine and fluorouracil

n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine has been researched along with fluorouracil in 5 studies

Compound Research Comparison

Studies
(n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine)		Trials
(n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine)		Recent Studies (post-2010)
(n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine)		Studies
(fluorouracil)		Trials
(fluorouracil)		Recent Studies (post-2010) (fluorouracil)
21455845,5629,30714,663

Protein Interaction Comparison

ProteinTaxonomyn(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine (IC50)fluorouracil (IC50)
Epidermal growth factor receptorHomo sapiens (human)0.32
Thymidylate synthaseMus musculus (house mouse)1.58
AromataseHomo sapiens (human)0.63

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Hofer, M; Pipalová, I; Pospísil, M; Vacek, A; Znojil, V1
Bar-Yehuda, S; Fishman, P; Gery, S; Madi, L; Shkapenuk, M; Silberman, D1
Hofer, M; Holá, J; Pospísil, M; Streitová, D; Vacek, A; Weiterová, L; Znojil, V1
Grden, M; Kitowska, A; Maciejewska, I; Pawelczyk, T; Sakowicz-Burkiewicz, M; Szutowicz, A1

Other Studies

5 other study(ies) available for n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine and fluorouracil

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Effects of stable adenosine receptor agonists on bone marrow hematopoietic cells as inferred from the cytotoxic action of 5-fluorouracil.
    Physiological research, 2004, Volume: 53, Issue:5

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cell Differentiation; Cell Proliferation; Cell Survival; Cells, Cultured; Drug Interactions; Fluorouracil; Hematopoiesis; Hematopoietic Stem Cells; Mice; Phenethylamines; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1

2004
CF101, an agonist to the A3 adenosine receptor, enhances the chemotherapeutic effect of 5-fluorouracil in a colon carcinoma murine model.
    Neoplasia (New York, N.Y.), 2005, Volume: 7, Issue:1

    Topics: Adenosine; Adenosine A3 Receptor Agonists; Animals; Antimetabolites, Antineoplastic; Cell Proliferation; Colonic Neoplasms; Colony-Forming Units Assay; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Humans; Mice; Mice, Inbred BALB C; Transplantation, Heterologous; Tumor Cells, Cultured

2005
Effects of adenosine A(3) receptor agonist on bone marrow granulocytic system in 5-fluorouracil-treated mice.
    European journal of pharmacology, 2006, May-24, Volume: 538, Issue:1-3

    Topics: Adenosine; Adenosine A3 Receptor Agonists; Animals; Bone Marrow Cells; Cell Proliferation; Fluorouracil; Granulocytes; Immunosuppressive Agents; Injections, Intraperitoneal; Male; Mice; Time Factors

2006
Differential effect of adenosine receptors on growth of human colon cancer HCT 116 and HT-29 cell lines.
    Archives of biochemistry and biophysics, 2013, Volume: 533, Issue:1-2

    Topics: Adenosine; Cell Proliferation; Cell Survival; Colonic Neoplasms; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Extracellular Space; Fluorouracil; Gene Expression Regulation, Neoplastic; HCT116 Cells; HT29 Cells; Humans; Protein Phosphatase 2; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A3; Receptors, Purinergic P1; Signal Transduction

2013