Page last updated: 2024-09-03

n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine and cgs 15943

n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine has been researched along with cgs 15943 in 7 studies

Compound Research Comparison

Studies
(n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine)
Trials
(n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine)
Recent Studies (post-2010)
(n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine)
Studies
(cgs 15943)
Trials
(cgs 15943)
Recent Studies (post-2010) (cgs 15943)
214558139028

Protein Interaction Comparison

ProteinTaxonomyn(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine (IC50)cgs 15943 (IC50)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformHomo sapiens (human)0.97
Adenosine receptor A3Homo sapiens (human)0.406
Adenosine receptor A1Rattus norvegicus (Norway rat)0.006
Adenosine receptor A3Rattus norvegicus (Norway rat)0.0607
Adenosine receptor A2aHomo sapiens (human)0.012
Adenosine receptor A2bHomo sapiens (human)0.6304
Adenosine receptor A2bRattus norvegicus (Norway rat)0.0028
Adenosine receptor A2aRattus norvegicus (Norway rat)0.0029
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformHomo sapiens (human)1.28
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformHomo sapiens (human)8.48
Casein kinase I isoform alphaHomo sapiens (human)0.82
Casein kinase I isoform deltaHomo sapiens (human)0.24
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Homo sapiens (human)0.11
Casein kinase I isoform epsilonHomo sapiens (human)0.49
DNA-dependent protein kinase catalytic subunitHomo sapiens (human)0.14

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (71.43)18.2507
2000's1 (14.29)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jacobson, KA; Kim, J; Schöneberg, T; van Rhee, AM; Wess, J1
Glashofer, M; Jacobson, KA; Jiang, Q; Lee, BX; van Rhee, AM1
Fredholm, BB; Hegler, J; Hessling, J; Klotz, KN; Kull, B; Lohse, MJ; Owman, C1
Baraldi, PG; Borea, PA; Cacciari, B; Gessi, S; Klotz, KN; Leung, E; Merighi, S; Romagnoli, R; Spalluto, G; Varani, K1
Federico, S; Jacobson, KA; Jayasekara, PS; Kozma, E; Moro, S; Paoletta, S; Spalluto, G; Squarcialupi, L1
Abbracchio, MP; Jacobson, KA; Jiang, JL; Kim, YC; Sei, Y; Yao, Y1
Jones, CA; Reeves, JJ; Sheehan, MJ; Vardey, CJ; Whelan, CJ1

Reviews

1 review(s) available for n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine and cgs 15943

ArticleYear
Fluorescent ligands for adenosine receptors.
    Bioorganic & medicinal chemistry letters, 2013, Jan-01, Volume: 23, Issue:1

    Topics: Boron Compounds; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Ligands; Protein Binding; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1

2013

Other Studies

6 other study(ies) available for n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine and cgs 15943

ArticleYear
Site-directed mutagenesis identifies residues involved in ligand recognition in the human A2a adenosine receptor.
    The Journal of biological chemistry, 1995, Jun-09, Volume: 270, Issue:23

    Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Histidine; Ligands; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Receptors, Purinergic P1; Structure-Activity Relationship

1995
Mutagenesis reveals structure-activity parallels between human A2A adenosine receptors and biogenic amine G protein-coupled receptors.
    Journal of medicinal chemistry, 1997, Aug-01, Volume: 40, Issue:16

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Affinity Labels; Animals; COS Cells; Enzyme-Linked Immunosorbent Assay; GTP-Binding Proteins; Humans; Hydrogen-Ion Concentration; Iodobenzenes; Ligands; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Receptor, Adenosine A2A; Receptors, Biogenic Amine; Receptors, Purinergic P1; Structure-Activity Relationship; Xanthines

1997
Comparative pharmacology of human adenosine receptor subtypes - characterization of stably transfected receptors in CHO cells.
    Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:1

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Base Composition; Binding, Competitive; CHO Cells; Cricetinae; Guanylate Cyclase; Humans; Phenethylamines; Phenylisopropyladenosine; Receptors, Purinergic P1; Stereoisomerism; Structure-Activity Relationship; Transfection; Xanthines

1998
[(3)H]MRE 3008F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors.
    Molecular pharmacology, 2000, Volume: 57, Issue:5

    Topics: Adenosine; Adenylyl Cyclase Inhibitors; Animals; Binding, Competitive; CHO Cells; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Phenylurea Compounds; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Receptor, Adenosine A3; Receptors, Purinergic P1; Triazoles; Tritium

2000
Adenosine A3 receptor agonists protect HL-60 and U-937 cells from apoptosis induced by A3 antagonists.
    Biochemical and biophysical research communications, 1997, Mar-17, Volume: 232, Issue:2

    Topics: Adenosine; Apoptosis; Dihydropyridines; DNA Fragmentation; Dose-Response Relationship, Drug; HL-60 Cells; Humans; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrazoles; Quinazolines; Triazoles

1997
Adenosine A3 receptors promote degranulation of rat mast cells both in vitro and in vivo.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1997, Volume: 46, Issue:5

    Topics: Adenosine; Administration, Cutaneous; Animals; Blood Proteins; Cell Degranulation; Cyproheptadine; Dinitrophenols; Female; Humans; In Vitro Techniques; Injections, Intravenous; Male; Mast Cells; Mice; p-Methoxy-N-methylphenethylamine; Pleura; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Rats, Wistar; Receptors, Purinergic P1; Serotonin; Serotonin Antagonists; Serum Albumin; Skin; Theophylline; Triazoles; Xanthines

1997