n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine and adenosine-5'-(n-ethylcarboxamide)

n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine has been researched along with adenosine-5'-(n-ethylcarboxamide) in 41 studies

Compound Research Comparison

Studies (n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine)	Trials (n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine)	Recent Studies (post-2010) (n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine)	Studies (adenosine-5'-(n-ethylcarboxamide))	Trials (adenosine-5'-(n-ethylcarboxamide))	Recent Studies (post-2010) (adenosine-5'-(n-ethylcarboxamide))
214	5	58	1,333	4	133

Protein Interaction Comparison

Protein	Taxonomy	adenosine-5'-(n-ethylcarboxamide) (IC50)
Adenosine receptor A3	Homo sapiens (human)	0.0097
Alpha-2B adrenergic receptor	Rattus norvegicus (Norway rat)	0.037
Alpha-2C adrenergic receptor	Rattus norvegicus (Norway rat)	0.037
Alpha-2A adrenergic receptor	Rattus norvegicus (Norway rat)	0.037
Adenosine receptor A1	Rattus norvegicus (Norway rat)	0.4498
Adenosine receptor A2a	Homo sapiens (human)	0.0336
Adenosine receptor A2b	Rattus norvegicus (Norway rat)	0.0175
Adenosine receptor A1	Homo sapiens (human)	0.0007
Adenosine receptor A2a	Rattus norvegicus (Norway rat)	0.0513
Adenosine receptor A1	Gallus gallus (chicken)	0.017

Research

Studies (41)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	11 (26.83)	18.2507
2000's	21 (51.22)	29.6817
2010's	8 (19.51)	24.3611
2020's	1 (2.44)	2.80

Authors

Authors	Studies
Cristalli, G; Esker, JL; Jacobson, KA; Ji, XD; Melman, N; Olah, ME; Schneller, SW; Secrist, JA; Siddiqi, SM; Tiwari, KN	1
Jacobson, KA; Kim, J; Schöneberg, T; van Rhee, AM; Wess, J	1
Fischer, B; Gallo-Rodriguez, C; Ji, XD; Melman, N; Olah, ME; Orlina, J; Pu, Q; Sanders, LH; Siegman, BD; van Galen, PJ	1
Glashofer, M; Jacobson, KA; Jiang, Q; Lee, BX; van Rhee, AM	1
Fredholm, BB; Hegler, J; Hessling, J; Klotz, KN; Kull, B; Lohse, MJ; Owman, C	1
Cappellacci, L; Franchetti, P; Grifantini, M; Lucacchini, A; Marchetti, S; Martini, C; Mazzoni, MR; Trincavelli, L	1
Baraldi, PG; Cacciari, B; Costanzi, S; Cristalli, G; Jacobson, KA; Ji, XD; Melman, N; Park, KS; Pineda de Las Infantas, MJ; Romagnoli, R; Spalluto, G; Vittori, S; Volpini, R	1
de Zwart, M; IJzerman, AP; Kooijman, H; Kourounakis, A; Link, R; Spek, AL; von Frijtag Drabbe Künzel, JK	1
Figler, H; Jin, X; Linden, J; Robeva, AS; Thai, T	1
Baraldi, PG; Borea, PA; Cacciari, B; Gessi, S; Klotz, KN; Leung, E; Merighi, S; Romagnoli, R; Spalluto, G; Varani, K	1
Belardinelli, L; Biaggioni, I; Feoktistov, I; Garland, EM; Goldstein, AE; Wells, JN; Zeng, D	1
Barak, D; Biadatti, T; Chen, W; Gao, ZG; Jacobson, KA; Johnson, CR; Kim, SG; Kim, SK; Lee, K	1
Baraldi, PG; Borea, PA; Bovero, A; Fruttarolo, F; Moorman, A; Pineda de Las Infantas, MJ; Preti, D; Romagnoli, R; Tabrizi, MA; Varani, K	1
Cappellacci, L; Costa, B; Franchetti, P; Grifantini, M; Klotz, KN; Lavecchia, A; Martini, C; Novellino, E; Pasqualini, M; Petrelli, R; Vita, P	1
Frazier, CR; Linden, J; Macdonald, TL; Zhu, R	1
Cohen, FE; Legname, G; May, BC; Prusiner, SB; Sherrill, J; Wallace, AC; Witkop, J; Zorn, JA	1
Auchampach, JA; Gao, ZG; Gizewski, E; Jacobson, KA; Kumar, D; Melman, A; Wan, TC	1
Axe, FU; Bembenek, SD; Butler, CR; Coles, F; Dunford, PJ; Edwards, JP; Fourie, AM; Grice, CA; Karlsson, L; Lundeen, K; Riley, JP; Savall, BM; Tays, KL; Wei, J; Williams, KN; Xue, X	1
Altenbach, RJ; Brioni, JD; Carr, TL; Chandran, P; Cowart, MD; Esbenshade, TA; Honore, P; Hsieh, GC; Lewis, LG; Liu, H; Manelli, AM; Marsh, KC; Milicic, I; Miller, TR; Strakhova, MI; Vortherms, TA; Wakefield, BD; Wetter, JM; Witte, DG	1
Chinn, M; Gao, ZG; Jacobson, KA; Kang, DW; Luecke, H; Tosh, DK; Yoo, LS	1
Federico, S; Jacobson, KA; Jayasekara, PS; Kozma, E; Moro, S; Paoletta, S; Spalluto, G; Squarcialupi, L	1
Anzini, M; Brogi, S; Butini, S; Campiani, G; Cappelli, A; Caselli, G; Castriconi, F; Gemma, S; Giordani, A; Giorgi, G; Giuliani, G; Lanza, M; Letari, O; Makovec, F; Manini, M; Mennuni, L; Valenti, S	1
Bednarski, M; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pękala, E; Powroźnik, B; Słoczyńska, K; Walczak, M; Waszkielewicz, AM; Żesławska, E	1
Filipek, B; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pańczyk, K; Pękala, E; Rapacz, A; Słoczyńska, K; Waszkielewicz, AM; Żelaszczyk, D; Żesławska, E	1
Ahn, S; Cheong, JH; Jacobson, KA; Jeong, LS; Jin, SH; Kim, G; Kim, HJ; Kim, J; Lee, E; Lee, M; Noh, M; Yu, J	1
Barkan, K; Kolocouris, A; Ladds, G; Lagarias, P; Stamatis, D; Vrontaki, E	1
Campbell, RG; Chen, E; Gao, ZG; Jacobson, KA; Liston, TE; Poe, RB; Salmaso, V; Suresh, RR	1
Hourani, SM; Prentice, DJ	1
Chessell, IP; Eastwood, C; Grundy, D; Humphrey, PP; Kirkup, AJ	1
Abbracchio, MP; Barbieri, D; Brambilla, R; Cattabeni, F; Ceruti, S; Franceschi, C; Jacobson, KA; Kim, YC; Klotz, KN; Lohse, MJ	1
Calacay, J; Cheng, K; Feighner, SD; Griffin, PR; Howard, AD; Leonard, RJ; Leong, D; Liu, K; Pomés, A; Pong, C; Schaeffer, J; Smith, AG; Smith, RG; Van der Ploeg, LH; Xu, Y	1
O'Sullivan, RG; Redmond, HP; Street, JT; Wakai, A; Wang, JH; Winter, DC	1
Antunes, E; Brain, SD; Camargo, EA; Costa, SK; de Nucci, G; Esquisatto, LC; Ribela, MT	1
Kim, KT; Kim, TD; Lee, JU; Seong, JK; Suh, BC	1
Breschi, MC; Calderone, V; Martinotti, E; Nieri, P	1
Hofer, M; Pipalová, I; Pospísil, M; Vacek, A; Znojil, V	1
Antunes, E; De Nucci, G; Priviero, F; Zanesco, A	1
Grden, M; Kocbuch, K; Pawelczyk, T; Podgorska, M; Szutowicz, A	1
Blakely, RD; Daws, LC; Hewlett, WA; Munn, JL; Steiner, JA; Zhu, CB	1
Brand, F; Fredholm, BB; Jacobson, KA; Klutz, AM; Schulte, G	1
Balasubramanian, R; Jacobson, KA; Keene, AM; Lloyd, J; Shainberg, A	1

Reviews

1 review(s) available for n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine and adenosine-5'-(n-ethylcarboxamide)

Article	Year
Fluorescent ligands for adenosine receptors. Bioorganic & medicinal chemistry letters, 2013, Jan-01, Volume: 23, Issue:1 Topics: Boron Compounds; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Ligands; Protein Binding; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1	2013

Other Studies

40 other study(ies) available for n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine and adenosine-5'-(n-ethylcarboxamide)

Article	Year
Search for new purine- and ribose-modified adenosine analogues as selective agonists and antagonists at adenosine receptors. Journal of medicinal chemistry, 1995, Mar-31, Volume: 38, Issue:7 Topics: Adenosine; Animals; Cell Membrane; CHO Cells; Corpus Striatum; Cricetinae; In Vitro Techniques; Magnetic Resonance Spectroscopy; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Radioligand Assay; Rats; Recombinant Proteins; Ribose; Structure-Activity Relationship	1995
Site-directed mutagenesis identifies residues involved in ligand recognition in the human A2a adenosine receptor. The Journal of biological chemistry, 1995, Jun-09, Volume: 270, Issue:23 Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Histidine; Ligands; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Receptors, Purinergic P1; Structure-Activity Relationship	1995
Structure-activity relationships of N6-benzyladenosine-5'-uronamides as A3-selective adenosine agonists. Journal of medicinal chemistry, 1994, Mar-04, Volume: 37, Issue:5 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Brain; Cell Membrane; Cerebral Cortex; CHO Cells; Cricetinae; Molecular Structure; Rats; Receptors, Purinergic P1; Structure-Activity Relationship	1994
Mutagenesis reveals structure-activity parallels between human A2A adenosine receptors and biogenic amine G protein-coupled receptors. Journal of medicinal chemistry, 1997, Aug-01, Volume: 40, Issue:16 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Affinity Labels; Animals; COS Cells; Enzyme-Linked Immunosorbent Assay; GTP-Binding Proteins; Humans; Hydrogen-Ion Concentration; Iodobenzenes; Ligands; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Receptor, Adenosine A2A; Receptors, Biogenic Amine; Receptors, Purinergic P1; Structure-Activity Relationship; Xanthines	1997
Comparative pharmacology of human adenosine receptor subtypes - characterization of stably transfected receptors in CHO cells. Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:1 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Base Composition; Binding, Competitive; CHO Cells; Cricetinae; Guanylate Cyclase; Humans; Phenethylamines; Phenylisopropyladenosine; Receptors, Purinergic P1; Stereoisomerism; Structure-Activity Relationship; Transfection; Xanthines	1998
2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies. Journal of medicinal chemistry, 1998, May-07, Volume: 41, Issue:10 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Animals; Brain; Cattle; Enzyme Inhibitors; In Vitro Techniques; Male; Membranes; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Testis	1998
Synthesis and biological activity of a new series of N6-arylcarbamoyl, 2-(Ar)alkynyl-N6-arylcarbamoyl, and N6-carboxamido derivatives of adenosine-5'-N-ethyluronamide as A1 and A3 adenosine receptor agonists. Journal of medicinal chemistry, 1998, Aug-13, Volume: 41, Issue:17 Topics: Adenosine-5'-(N-ethylcarboxamide); Animals; Brain; Carbamates; Cell Line; Cell Membrane; Drug Design; Guanosine 5'-O-(3-Thiotriphosphate); Indicators and Reagents; Kinetics; Mast Cells; Molecular Structure; Purinergic P1 Receptor Agonists; Rats; Receptor, Adenosine A3; Recombinant Proteins; Structure-Activity Relationship	1998
5'-N-substituted carboxamidoadenosines as agonists for adenosine receptors. Journal of medicinal chemistry, 1999, Apr-22, Volume: 42, Issue:8 Topics: Adenosine; Animals; Cell Line; Cerebral Cortex; CHO Cells; Corpus Striatum; Cricetinae; Crystallography, X-Ray; Cyclic AMP; Humans; In Vitro Techniques; Molecular Conformation; Purinergic P1 Receptor Agonists; Radioligand Assay; Rats; Receptors, Purinergic P1; Structure-Activity Relationship	1999
Characterization of human A(2B) adenosine receptors: radioligand binding, western blotting, and coupling to G(q) in human embryonic kidney 293 cells and HMC-1 mast cells. Molecular pharmacology, 1999, Volume: 56, Issue:4 Topics: Animals; Anti-Asthmatic Agents; Blotting, Western; Calcium; Cell Degranulation; Cells, Cultured; CHO Cells; Cricetinae; Cyclic AMP; GTP-Binding Proteins; Humans; Kidney; Mast Cells; Purinergic P1 Receptor Agonists; Radioligand Assay; Receptor, Adenosine A2B; Receptors, Purinergic P1; Theophylline; Type C Phospholipases; Xanthines	1999
[(3)H]MRE 3008F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors. Molecular pharmacology, 2000, Volume: 57, Issue:5 Topics: Adenosine; Adenylyl Cyclase Inhibitors; Animals; Binding, Competitive; CHO Cells; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Phenylurea Compounds; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Receptor, Adenosine A3; Receptors, Purinergic P1; Triazoles; Tritium	2000
Inhibition of human mast cell activation with the novel selective adenosine A(2B) receptor antagonist 3-isobutyl-8-pyrrolidinoxanthine (IPDX)(2). Biochemical pharmacology, 2001, Nov-01, Volume: 62, Issue:9 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Anti-Asthmatic Agents; Cells, Cultured; Humans; Mast Cells; Purinergic P1 Receptor Antagonists; Pyrrolidinones; Receptor, Adenosine A2B; Receptors, Purinergic P1; Structure-Activity Relationship; Vasodilator Agents; Xanthine; Xanthines	2001
Structural determinants of A(3) adenosine receptor activation: nucleoside ligands at the agonist/antagonist boundary. Journal of medicinal chemistry, 2002, Sep-26, Volume: 45, Issue:20 Topics: Adenosine; Animals; Binding, Competitive; CHO Cells; Cricetinae; Epoxy Compounds; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Ligands; Models, Molecular; Mutation; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Receptor, Adenosine A3; Receptors, Purinergic P1; Ribose; Spiro Compounds; Stereoisomerism; Structure-Activity Relationship	2002
Synthesis and biological evaluation of novel N6-[4-(substituted)sulfonamidophenylcarbamoyl]adenosine-5'-uronamides as A3 adenosine receptor agonists. Journal of medicinal chemistry, 2004, Oct-21, Volume: 47, Issue:22 Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Adenosine A3 Receptor Agonists; Amides; Animals; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Humans; Ligands; Radioligand Assay; Structure-Activity Relationship; Sulfonamides; Uronic Acids	2004
Synthesis, biological evaluation, and molecular modeling of ribose-modified adenosine analogues as adenosine receptor agonists. Journal of medicinal chemistry, 2005, Mar-10, Volume: 48, Issue:5 Topics: Adenosine; Adenylyl Cyclase Inhibitors; Animals; Binding, Competitive; Brain; Cattle; CHO Cells; Cricetinae; Cricetulus; Humans; In Vitro Techniques; Models, Molecular; Purinergic P1 Receptor Agonists; Radioligand Assay; Rats; Receptors, Purinergic P1; Ribose	2005
N6-ethyl-2-alkynyl NECAs, selective human A3 adenosine receptor agonists. Bioorganic & medicinal chemistry letters, 2006, May-01, Volume: 16, Issue:9 Topics: Adenosine A3 Receptor Agonists; Adenosine-5'-(N-ethylcarboxamide); Cell Line; Humans; Molecular Structure; Structure-Activity Relationship	2006
Structure-activity relationship study of prion inhibition by 2-aminopyridine-3,5-dicarbonitrile-based compounds: parallel synthesis, bioactivity, and in vitro pharmacokinetics. Journal of medicinal chemistry, 2007, Jan-11, Volume: 50, Issue:1 Topics: Aminopyridines; Animals; Cell Line, Tumor; Combinatorial Chemistry Techniques; Membranes, Artificial; Mice; Models, Molecular; Nitriles; Permeability; PrPSc Proteins; Solubility; Structure-Activity Relationship	2007
Design of (N)-methanocarba adenosine 5'-uronamides as species-independent A3 receptor-selective agonists. Bioorganic & medicinal chemistry letters, 2008, May-01, Volume: 18, Issue:9 Topics: Adenosine; Adenosine A3 Receptor Agonists; Alkanes; Animals; Binding Sites; Drug Design; Humans; Hydrophobic and Hydrophilic Interactions; Mice; Models, Chemical; Nucleosides; Ribose; Structure-Activity Relationship	2008
Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity. Journal of medicinal chemistry, 2008, Jul-24, Volume: 51, Issue:14 Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Catalysis; Dogs; Drug Evaluation, Preclinical; Enzyme Inhibitors; Epoxide Hydrolases; Humans; Magnetic Resonance Spectroscopy; Mice; Structure-Activity Relationship	2008
cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia. Journal of medicinal chemistry, 2008, Nov-27, Volume: 51, Issue:22 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Carrageenan; Disease Models, Animal; Drug Design; Drug Evaluation, Preclinical; Humans; Hyperalgesia; Ligands; Mice; Molecular Structure; Pain; Peritonitis; Quinazolines; Rats; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Stereoisomerism; Structure-Activity Relationship	2008
2-Dialkynyl derivatives of (N)-methanocarba nucleosides: 'Clickable' A(3) adenosine receptor-selective agonists. Bioorganic & medicinal chemistry, 2010, Jan-15, Volume: 18, Issue:2 Topics: Adenosine A3 Receptor Agonists; Alkynes; Animals; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Drug Design; Humans; Molecular Structure; Nucleosides; Receptor, Adenosine A3; Stereoisomerism; Structure-Activity Relationship	2010
Synthesis and structure-activity relationship studies in serotonin 5-HT(1A) receptor agonists based on fused pyrrolidone scaffolds. European journal of medicinal chemistry, 2013, Volume: 63 Topics: Animals; Area Under Curve; Humans; Intestinal Absorption; Ligands; Male; Metabolic Clearance Rate; Models, Chemical; Models, Molecular; Molecular Structure; Protein Binding; Protein Structure, Tertiary; Pyrrolidinones; Radioligand Assay; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT3; Serotonin 5-HT1 Receptor Agonists; Structure-Activity Relationship	2013
Design, physico-chemical properties and biological evaluation of some new N-[(phenoxy)alkyl]- and N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols as anticonvulsant agents. Bioorganic & medicinal chemistry, 2016, Apr-15, Volume: 24, Issue:8 Topics: Amino Alcohols; Animals; Anticonvulsants; Chemistry, Physical; Dose-Response Relationship, Drug; Drug Design; Epilepsy; Male; Mice; Microsomes, Liver; Molecular Structure; Pilocarpine	2016
Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH Bioorganic & medicinal chemistry, 2017, 01-15, Volume: 25, Issue:2 Topics: Amino Alcohols; Animals; Anticonvulsants; Crystallography, X-Ray; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Mice; Models, Molecular; Molecular Structure; Rats; Seizures; Structure-Activity Relationship	2017
Polypharmacology of N Journal of medicinal chemistry, 2017, 09-14, Volume: 60, Issue:17 Topics: Adenosine; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Adiponectin; Animals; Cell Line; Diabetes Mellitus, Experimental; Humans; Hypoglycemic Agents; Insulin Resistance; Ligands; Male; Mice; Mice, Inbred C57BL; Polypharmacology; PPAR delta; PPAR gamma; Receptor, Adenosine A3	2017
Structural Characterization of Agonist Binding to an A Journal of medicinal chemistry, 2019, 10-10, Volume: 62, Issue:19 Topics: Adenosine; Adenosine A3 Receptor Agonists; Animals; Binding Sites; CHO Cells; Cricetinae; Cricetulus; Humans; Hydrogen Bonding; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Receptor, Adenosine A3; Signal Transduction; Thermodynamics	2019
Selective A ACS medicinal chemistry letters, 2022, Apr-14, Volume: 13, Issue:4 Topics:	2022
Adenosine analogues relax guinea-pig taenia caeci via an adenosine A2B receptor and a xanthine-resistant site. European journal of pharmacology, 1997, Mar-26, Volume: 323, Issue:1 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cecum; Dose-Response Relationship, Drug; Guinea Pigs; Male; Muscle Relaxation; Muscle, Smooth; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Theophylline; Triazines; Triazoles; Vasodilator Agents; Xanthines	1997
Characterization of adenosine receptors evoking excitation of mesenteric afferents in the rat. British journal of pharmacology, 1998, Volume: 125, Issue:6 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Analgesics; Animals; Bethanechol; Female; Jejunum; Male; Muscarinic Agonists; Neurons, Afferent; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1	1998
Activation of the A3 adenosine receptor affects cell cycle progression and cell growth. Naunyn-Schmiedeberg's archives of pharmacology, 2000, Volume: 361, Issue:3 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Analysis of Variance; Animals; Antineoplastic Agents; Cell Cycle; Cell Line; Cell Membrane; Cell Survival; CHO Cells; Cricetinae; Dihydropyridines; Flow Cytometry; Humans; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A3; Receptors, Purinergic P1; Transfection; Triazoles	2000
Adenosine: A partial agonist of the growth hormone secretagogue receptor. Biochemical and biophysical research communications, 2000, Oct-05, Volume: 276, Issue:3 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Aequorin; Animals; Binding Sites; Cell Extracts; Cell Line; Chromatography, High Pressure Liquid; Dopamine; Humans; Hypothalamus; Indoles; Ligands; Luminescent Measurements; Mass Spectrometry; Models, Biological; Mutagenesis, Site-Directed; Neurons; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Ghrelin; Spiro Compounds; Swine; Theophylline	2000
Adenosine inhibits neutrophil vascular endothelial growth factor release and transendothelial migration via A2B receptor activation. Shock (Augusta, Ga.), 2001, Volume: 15, Issue:4 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); CD18 Antigens; Cell Movement; Cells, Cultured; Chemotaxis, Leukocyte; Depression, Chemical; Dose-Response Relationship, Drug; Endothelial Growth Factors; Endothelium, Vascular; Humans; Intercellular Adhesion Molecule-1; Lymphokines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A2B; Receptors, Purinergic P1; Recombinant Proteins; Theobromine; Tumor Necrosis Factor-alpha; Umbilical Veins; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors	2001
The plasma protein extravasation induced by adenosine and its analogues in the rat dorsal skin: evidence for the involvement of capsaicin sensitive primary afferent neurones and mast cells. British journal of pharmacology, 2001, Volume: 134, Issue:1 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Blood Proteins; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Female; Injections, Intradermal; Isotonic Solutions; Male; Mast Cells; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; p-Methoxy-N-methylphenethylamine; Peptide Fragments; Piperidines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinuclidines; Rats; Rats, Wistar; Receptors, Neurokinin-2; Skin; Substance P; Theobromine	2001
Pharmacological characterization of adenosine receptors in PGT-beta mouse pineal gland tumour cells. British journal of pharmacology, 2001, Volume: 134, Issue:1 Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Calcium; Colforsin; Cyclic AMP; Dihydropyridines; Dose-Response Relationship, Drug; Enzyme Activation; Estrenes; Gene Expression Regulation, Neoplastic; GTP-Binding Proteins; Inositol 1,4,5-Trisphosphate; Isoproterenol; Mice; Mice, Inbred CBA; Pertussis Toxin; Phospholipases; Pinealoma; Pyrrolidinones; Receptor, Adenosine A2B; Receptor, Adenosine A3; Receptors, Purinergic P1; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured; Virulence Factors, Bordetella	2001
Adenosine-mediated hypotension in in vivo guinea-pig: receptors involved and role of NO. British journal of pharmacology, 2001, Volume: 134, Issue:4 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Blood Pressure; Diphenhydramine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Heart Rate; Hypotension; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Triazines; Triazoles; Vasodilator Agents; Xanthines	2001
Effects of stable adenosine receptor agonists on bone marrow hematopoietic cells as inferred from the cytotoxic action of 5-fluorouracil. Physiological research, 2004, Volume: 53, Issue:5 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cell Differentiation; Cell Proliferation; Cell Survival; Cells, Cultured; Drug Interactions; Fluorouracil; Hematopoiesis; Hematopoietic Stem Cells; Mice; Phenethylamines; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1	2004
Negative chronotropic response to adenosine receptor stimulation in rat right atria after run training. Clinical and experimental pharmacology & physiology, 2004, Volume: 31, Issue:10 Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A3 Receptor Agonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Depression, Chemical; Heart; Heart Atria; Heart Rate; In Vitro Techniques; Male; Physical Conditioning, Animal; Physical Exertion; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Vasodilator Agents	2004
Expression of adenosine receptors in cardiac fibroblasts as a function of insulin and glucose level. Archives of biochemistry and biophysics, 2006, Nov-01, Volume: 455, Issue:1 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Blotting, Western; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Fibroblasts; Gene Expression; Glucose; Heart Ventricles; Insulin; Male; Phenethylamines; Protein Isoforms; Rats; Rats, Wistar; Receptors, Purinergic P1; RNA, Messenger; Triazines; Triazoles	2006
Rapid stimulation of presynaptic serotonin transport by A(3) adenosine receptors. The Journal of pharmacology and experimental therapeutics, 2007, Volume: 322, Issue:1 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Biological Transport; Cyclic GMP-Dependent Protein Kinases; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A3; Serotonin; Serotonin Plasma Membrane Transport Proteins; Synaptosomes	2007
Adenosine A(2A) receptor dynamics studied with the novel fluorescent agonist Alexa488-APEC. European journal of pharmacology, 2008, Aug-20, Volume: 590, Issue:1-3 Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine-5'-(N-ethylcarboxamide); Animals; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Fluorescent Dyes; Humans; Radioligand Assay; Receptor, Adenosine A2A	2008
Multivalent dendrimeric and monomeric adenosine agonists attenuate cell death in HL-1 mouse cardiomyocytes expressing the A(3) receptor. Biochemical pharmacology, 2010, Jul-15, Volume: 80, Issue:2 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cell Death; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Cytoprotection; Dendrimers; Gene Expression Regulation; Humans; Hydrogen Peroxide; Mice; Myocytes, Cardiac; Oxidants; Protein Binding; Receptors, Purinergic P1; Transfection	2010