Page last updated: 2024-09-04

n(5)-hydroxy-l-arginine and arginine

n(5)-hydroxy-l-arginine has been researched along with arginine in 13 studies

Compound Research Comparison

Studies
(n(5)-hydroxy-l-arginine)
Trials
(n(5)-hydroxy-l-arginine)
Recent Studies (post-2010)
(n(5)-hydroxy-l-arginine)
Studies
(arginine)
Trials
(arginine)
Recent Studies (post-2010) (arginine)
130046,3881,68811,176

Protein Interaction Comparison

ProteinTaxonomyn(5)-hydroxy-l-arginine (IC50)arginine (IC50)
Cationic amino acid transporter 3Homo sapiens (human)283

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's10 (76.92)18.2507
2000's2 (15.38)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gryglewski, RJ; Hecker, M; Southan, GJ; Swierkosz, TA; Vane, JR; Zembowicz, A1
Thiemermann, C; Vane, JR; Walder, CE1
Chłopicki, S; Gryglewski, RJ; Radziszewski, W; Vane, JR; Zembowicz, A1
Babbedge, R; Brave, SR; Gibson, A; Hart, SL; Hobbs, AJ; Moore, PK; Tucker, JF; Wallace, P1
Feldman, PL; Griffith, OW; Kwon, NS; Nathan, CF; Stuehr, DJ; Wiseman, J1
Ito-Kagawa, M; Kondo, S; Koyama, Y1
Marletta, MA; Pufahl, RA1
Masters, BS; McMillan, K1
Fukuto, JM1
Masters, BS; McMillan, K; Salerno, JC1
Ikeno, M; Ishikawa, T; Mochida, M; Nagai, R; Oyama, Y; Saito, Y; Sakamaki, T; Sato, K1
Arvai, AS; Crane, BR; Getzoff, ED; Ghosh, S; Stuehr, DJ; Tainer, JA1
Donzelli, S; Espey, MG; Flores-Santana, W; Huang, J; King, SB; Miranda, KM; Stuehr, DJ; Switzer, CH; Wink, DA; Yeh, GC1

Other Studies

13 other study(ies) available for n(5)-hydroxy-l-arginine and arginine

ArticleYear
Mechanisms of the endothelium-dependent relaxation induced by NG-hydroxy-L-arginine.
    Journal of cardiovascular pharmacology, 1992, Volume: 20 Suppl 12

    Topics: Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Cells, Cultured; Endothelium, Vascular; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rabbits; Vasodilation

1992
NG-hydroxy-L-arginine prevents the haemodynamic effects of nitric oxide synthesis inhibition in the anaesthetized rat.
    British journal of pharmacology, 1992, Volume: 107, Issue:2

    Topics: Animals; Arginine; Blood Pressure; Hemodynamics; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Renal Circulation; Vascular Resistance

1992
NG-hydroxy-L-arginine and hydroxyguanidine potentiate the biological activity of endothelium-derived relaxing factor released from the rabbit aorta.
    Biochemical and biophysical research communications, 1992, Dec-15, Volume: 189, Issue:2

    Topics: Acetylcholine; Animals; Antimetabolites; Aorta; Arginine; Dose-Response Relationship, Drug; Drug Synergism; Endothelium, Vascular; Guanidines; Hydroxylamines; In Vitro Techniques; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Perfusion; Rabbits; Vasodilation

1992
An investigation of some S-nitrosothiols, and of hydroxy-arginine, on the mouse anococcygeus.
    British journal of pharmacology, 1992, Volume: 107, Issue:3

    Topics: Animals; Antimetabolites; Arginine; Autonomic Nervous System; Carbachol; Cold Temperature; Hemoglobins; Hydroquinones; In Vitro Techniques; Male; Mercaptoethanol; Mice; Muscle Contraction; Muscle Relaxation; Muscles; Nitroso Compounds; S-Nitrosothiols; Stereoisomerism

1992
N omega-hydroxy-L-arginine is an intermediate in the biosynthesis of nitric oxide from L-arginine.
    The Journal of biological chemistry, 1991, Apr-05, Volume: 266, Issue:10

    Topics: Amino Acid Oxidoreductases; Arginine; Free Radicals; Hydroxylation; Kinetics; Macrophages; NADP; Nitric Oxide; Nitric Oxide Synthase; Oxidation-Reduction; Substrate Specificity

1991
Peptide antibiotic K-582 production in relation to amino acid metabolism in Metarrhizium anisopliae.
    The Journal of antibiotics, 1984, Volume: 37, Issue:5

    Topics: Amino Acids; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Arginine; Carbon; Glycerol; Mitosporic Fungi; Peptide Biosynthesis; Peptides

1984
Oxidation of NG-hydroxy-L-arginine by nitric oxide synthase: evidence for the involvement of the heme in catalysis.
    Biochemical and biophysical research communications, 1993, Jun-30, Volume: 193, Issue:3

    Topics: Amino Acid Oxidoreductases; Anaerobiosis; Animals; Arginine; Carbon Monoxide; Catalysis; Cell Line; Heme; Kinetics; Macrophages; Mice; Nitric Oxide Synthase; Oxidation-Reduction; Spectrophotometry; Substrate Specificity

1993
Optical difference spectrophotometry as a probe of rat brain nitric oxide synthase heme-substrate interaction.
    Biochemistry, 1993, Sep-28, Volume: 32, Issue:38

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Brain; Cell Line; Heme; Humans; Kidney; Kinetics; Nitric Oxide Synthase; omega-N-Methylarginine; Protein Binding; Rats; Spectrophotometry; Transfection

1993
Chemistry of N-hydroxy-L-arginine.
    Methods in enzymology, 1996, Volume: 268

    Topics: Arginine; Chromatography, Thin Layer; Guanidines; Hydroxylamines; Indicators and Reagents; Magnetic Resonance Spectroscopy; Molecular Structure; Nitric Oxide

1996
Binding of intermediate, product, and substrate analogs to neuronal nitric oxide synthase: ferriheme is sensitive to ligand-specific effects in the L-arginine binding site.
    Biochemistry, 1996, Sep-10, Volume: 35, Issue:36

    Topics: Animals; Arginine; Binding Sites; Cell Line; Citrulline; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Heme; Kidney; Neurons; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Ornithine; Rats

1996
Synthetic N omega-hydroxy-L-arginine causes endothelium-dependent vascular relaxation both in vitro and in vivo.
    Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 1995, Volume: 31, Issue:6

    Topics: Animals; Arginine; Arterioles; Endothelium, Vascular; Male; Rats; Rats, Wistar; Vasodilation; Vasodilator Agents

1995
Structures of the N(omega)-hydroxy-L-arginine complex of inducible nitric oxide synthase oxygenase dimer with active and inactive pterins.
    Biochemistry, 2000, Apr-25, Volume: 39, Issue:16

    Topics: Animals; Arginine; Binding Sites; Biopterins; Catalysis; Crystallography, X-Ray; Dimerization; Heme; Hydrogen Bonding; Iron; Mice; Models, Chemical; Models, Molecular; Molecular Sequence Data; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidation-Reduction; Oxygen; Oxygenases; Protein Conformation; Structure-Activity Relationship

2000
Generation of nitroxyl by heme protein-mediated peroxidation of hydroxylamine but not N-hydroxy-L-arginine.
    Free radical biology & medicine, 2008, Sep-01, Volume: 45, Issue:5

    Topics: Arginine; Cell Line, Tumor; Electron Spin Resonance Spectroscopy; Glutathione; Hemeproteins; Humans; Hydroxylamine; Nitrogen Oxides; Peroxides

2008