Page last updated: 2024-09-04

n(4)-octadecyl-1-arabinofuranosylcytosine and cytarabine

n(4)-octadecyl-1-arabinofuranosylcytosine has been researched along with cytarabine in 5 studies

Compound Research Comparison

Studies
(n(4)-octadecyl-1-arabinofuranosylcytosine)
Trials
(n(4)-octadecyl-1-arabinofuranosylcytosine)
Recent Studies (post-2010)
(n(4)-octadecyl-1-arabinofuranosylcytosine)
Studies
(cytarabine)
Trials
(cytarabine)
Recent Studies (post-2010) (cytarabine)
50115,4872,4243,188

Protein Interaction Comparison

ProteinTaxonomyn(4)-octadecyl-1-arabinofuranosylcytosine (IC50)cytarabine (IC50)
nuclear receptor coactivator 3 isoform aHomo sapiens (human)7.533
E3 ubiquitin-protein ligase Mdm2Homo sapiens (human)0.02

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (60.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Horber, DH; Odermatt, B; Schott, H; Schwendener, RA1
Hänseler, E; Rentsch, KM; Schott, H; Schwendener, RA1
Koller-Lucae, SK; Schott, H; Schwendener, RA1
Depenbrock, H; Friedl, K; Hanauske, AR; Schott, H; Schwendener, RA1
Dzięgiel, P; Gomułkiewicz, A; Gziut, M; Merwid-Ląd, A; Nowak, B; Piasecki, T; Pieśniewska, M; Sozański, T; Szeląg, A; Szuba, A; Trocha, M; Wiśniewski, J1

Other Studies

5 other study(ies) available for n(4)-octadecyl-1-arabinofuranosylcytosine and cytarabine

ArticleYear
Oral antitumour activity in murine L1210 leukaemia and pharmacological properties of liposome formulations of N4-alkyl derivatives of 1-beta-D-arabinofuranosylcytosine.
    Journal of cancer research and clinical oncology, 1996, Volume: 122, Issue:2

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Cytarabine; Drug Carriers; Female; Hemolysis; Humans; Leukemia L1210; Liposomes; Mice; Mice, Inbred ICR; Neoplasm Transplantation; Tissue Distribution

1996
Sensitive high-performance liquid chromatographic method for the determination of N4-hexadecyl- and N4-octadecyl-1-beta-D-arabinofuranosylcytosine in plasma and erythrocytes.
    Journal of chromatography. B, Biomedical applications, 1995, Nov-17, Volume: 673, Issue:2

    Topics: Animals; Antineoplastic Agents; Butanols; Chromatography, High Pressure Liquid; Cytarabine; Erythrocytes; Female; Humans; Mice; Mice, Inbred ICR; Reproducibility of Results; Sensitivity and Specificity; Sonication; Urea

1995
Low density lipoprotein and liposome mediated uptake and cytotoxic effect of N4-octadecyl-1-beta-D-arabinofuranosylcytosine in Daudi lymphoma cells.
    British journal of cancer, 1999, Volume: 80, Issue:10

    Topics: Antineoplastic Agents; Burkitt Lymphoma; Cell Survival; Cytarabine; Drug Carriers; Endocytosis; Hot Temperature; Humans; Lipoproteins, LDL; Liposomes; Protein Binding; Receptors, LDL; Tumor Cells, Cultured

1999
In vitro activity of liposomal N4octadecyl-1-beta-D-arabinofuranosylcytosine (NOAC), a new lipophilic derivative of 1-beta-D-arabinofuranocylcytosine on biopsized clonogenic human tumor cells and hematopoietic precursor cells.
    Investigational new drugs, 2001, Volume: 19, Issue:3

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Clone Cells; Cytarabine; Doxorubicin; Hematopoietic Stem Cells; Humans; Liposomes; Tumor Cells, Cultured; Tumor Stem Cell Assay

2001
The impact of sitagliptin, inhibitor of dipeptidyl peptidase-4 (DPP-4), on the ADMA-DDAH-NO pathway in ischemic and reperfused rat livers.
    Advances in clinical and experimental medicine : official organ Wroclaw Medical University, 2018, Volume: 27, Issue:11

    Topics: Amidohydrolases; Animals; Arginine; Cytarabine; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Ischemia; Liver; Nitric Oxide; Protein-Arginine N-Methyltransferases; Rats; Reperfusion Injury; Sitagliptin Phosphate

2018