n(4)-hexadecyl-1-arabinofuranosylcytosine has been researched along with cytarabine in 8 studies
| Studies (n(4)-hexadecyl-1-arabinofuranosylcytosine) | Trials (n(4)-hexadecyl-1-arabinofuranosylcytosine) | Recent Studies (post-2010) (n(4)-hexadecyl-1-arabinofuranosylcytosine) | Studies (cytarabine) | Trials (cytarabine) | Recent Studies (post-2010) (cytarabine) |
|---|---|---|---|---|---|
| 8 | 0 | 0 | 15,487 | 2,424 | 3,188 |
| Protein | Taxonomy | n(4)-hexadecyl-1-arabinofuranosylcytosine (IC50) | cytarabine (IC50) |
|---|---|---|---|
| nuclear receptor coactivator 3 isoform a | Homo sapiens (human) | 7.533 | |
| E3 ubiquitin-protein ligase Mdm2 | Homo sapiens (human) | 0.02 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 7 (87.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| An, SH; Buchheit, DJ; Hong, CI; Kirisits, AJ; Nechaev, A; Schliselfeld, L; West, CR | 1 |
| Schott, H; Schwendener, RA | 2 |
| Horber, DH; Schott, H; Schwendener, RA | 2 |
| Horber, DH; Schott, H; Schwendener, RA; von Ballmoos, P | 1 |
| Horber, DH; Odermatt, B; Schott, H; Schwendener, RA | 1 |
| Hänseler, E; Rentsch, KM; Schott, H; Schwendener, RA | 1 |
8 other study(ies) available for n(4)-hexadecyl-1-arabinofuranosylcytosine and cytarabine
| Article | Year |
|---|---|
Nucleoside conjugates. 10. Synthesis and antitumor activity of 1-beta-D-arabinofuranosylcytosine 5'-diphosphate-1,2-dipalmitins.
Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Cytarabine; Drug Resistance; Drug Therapy; Leukemia L1210; Mice; Mice, Inbred DBA; Prodrugs; Stereoisomerism; Structure-Activity Relationship | 1988 |
Treatment of L1210 murine leukemia with liposome-incorporated N4-hexadecyl-1-beta-D-arabinofuranosyl cytosine.
Topics: Animals; Cytarabine; Drug Carriers; Drug Screening Assays, Antitumor; Leukemia L1210; Liposomes | 1992 |
Cellular pharmacology of N4-hexadecyl-1-beta-D-arabinofuranosylcytosine in the human leukemic cell lines K-562 and U-937.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Arabinofuranosylcytosine Triphosphate; Cell Differentiation; Cytarabine; Dipyridamole; DNA; Drug Carriers; Drug Interactions; Half-Life; Humans; Leukemia; Liposomes; Tumor Cells, Cultured | 1995 |
Cell cycle-dependent cytotoxicity and induction of apoptosis by liposomal N4-hexadecyl-1-beta-D-arabinofuranosylcytosine.
Topics: Antineoplastic Agents; Apoptosis; Cytarabine; DNA Replication; DNA, Neoplasm; Drug Carriers; Drug Resistance, Neoplasm; HL-60 Cells; Humans; Liposomes; S Phase; Tumor Stem Cell Assay | 1995 |
Cellular pharmacology of a liposomal preparation of N4-hexadecyl-1-beta-D-arabinofuranosylcytosine, a lipophilic derivative of 1-beta-D-arabinofuranosylcytosine.
Topics: Animals; Antineoplastic Agents; Arabinofuranosylcytosine Triphosphate; Cytarabine; Deamination; DNA; DNA, Neoplasm; Drug Resistance; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Liposomes; Mice; Microsomes, Liver; Tumor Cells, Cultured | 1995 |
Oral antitumour activity in murine L1210 leukaemia and pharmacological properties of liposome formulations of N4-alkyl derivatives of 1-beta-D-arabinofuranosylcytosine.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Cytarabine; Drug Carriers; Female; Hemolysis; Humans; Leukemia L1210; Liposomes; Mice; Mice, Inbred ICR; Neoplasm Transplantation; Tissue Distribution | 1996 |
Sensitive high-performance liquid chromatographic method for the determination of N4-hexadecyl- and N4-octadecyl-1-beta-D-arabinofuranosylcytosine in plasma and erythrocytes.
Topics: Animals; Antineoplastic Agents; Butanols; Chromatography, High Pressure Liquid; Cytarabine; Erythrocytes; Female; Humans; Mice; Mice, Inbred ICR; Reproducibility of Results; Sensitivity and Specificity; Sonication; Urea | 1995 |
Synthesis and structure-activity studies in vivo of liposomal phospholipid-N4-palmitoyl- and N4-hexadecyl-1-beta-D-arabinofuranosylcytosine conjugates.
Topics: Animals; Antimetabolites, Antineoplastic; Cytarabine; Drug Carriers; Female; Leukemia L1210; Liposomes; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Molecular Structure; Phospholipids; Prodrugs; Structure-Activity Relationship | 1996 |