Page last updated: 2024-09-04

n(4)-acetylsulfisoxazole and sulfamethoxazole

n(4)-acetylsulfisoxazole has been researched along with sulfamethoxazole in 1 studies

*Sulfamethoxazole: A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208) [MeSH]

*Sulfamethoxazole: A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208) [MeSH]

Compound Research Comparison

Studies
(n(4)-acetylsulfisoxazole)
Trials
(n(4)-acetylsulfisoxazole)
Recent Studies (post-2010)
(n(4)-acetylsulfisoxazole)
Studies
(sulfamethoxazole)
Trials
(sulfamethoxazole)
Recent Studies (post-2010) (sulfamethoxazole)
6005,8136801,216

Protein Interaction Comparison

ProteinTaxonomyn(4)-acetylsulfisoxazole (IC50)sulfamethoxazole (IC50)
Dihydropteroate synthaseEscherichia coli K-124.7
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)4.7
Dihydrofolate reductasePneumocystis carinii0.1
Endothelin-1 receptorRattus norvegicus (Norway rat)4

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bisaha, S; Dickey, J; Floyd, DM; Girotra, RN; Gougoutas, JZ; Kozlowski, M; Lee, VG; Liu, EC; Malley, MF; Stein, PD1

Other Studies

1 other study(ies) available for n(4)-acetylsulfisoxazole and sulfamethoxazole

ArticleYear
Discovery and structure-activity relationships of sulfonamide ETA-selective antagonists.
    Journal of medicinal chemistry, 1995, Apr-14, Volume: 38, Issue:8

    Topics: Animals; Benzenesulfonamides; Carotid Arteries; Cell Line; Endothelin Receptor Antagonists; In Vitro Techniques; Muscle, Smooth, Vascular; Rabbits; Radioligand Assay; Rats; Receptor, Endothelin A; Structure-Activity Relationship; Sulfonamides

1995