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n(4)-acetylsulfamethoxazole and sulfamethoxazole

n(4)-acetylsulfamethoxazole has been researched along with sulfamethoxazole in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199012 (48.00)18.7374
1990's9 (36.00)18.2507
2000's1 (4.00)29.6817
2010's2 (8.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Aguilar-Cota, ME; Castañeda-Hernández, G; Flores-Murrieta, FJ; Hong, E; Menéndez, JC1
Athanasiou, G; Avgerinos, A; Malamataris, S1
Laizure, SC; Lancaster, DJ; Palte, S; Stein, DS; Stevens, RC; Terry, D; Weems, JJ; Williams, CL1
Laizure, SC; Stein, DS; Stevens, RC; Williams, CL1
Hutabarat, RM; McNamara, S; Ramsey, B; Sahajwalla, C; Smith, AL; Unadkat, JD1
Hellerstein, MK; Kaempfer, S; Kletke, C; Shackleton, CH; Wu, K1
Holden, CL; Laizure, SC; Stevens, RC1
Nouws, JF; Vree, ML; Vree, TB1
Hekster, YA; Nouws, JF; Vree, JB; Vree, TB1
Advenier, C; Cordonnier, P; Ducreuzet, C; Gobert, C; Lajoie, D; Pays, M; Varoquaux, O1
Vree, JB; Vree, TB1
Vree, ML; Vree, TB1
Advenier, C; Chapalain, JP; Cordonnier, P; Lamine, L; Pays, M; Spreux-Varoquaux, O1
Ericson, JF; Opheim, KE; Siber, GR; Smith, AL; Weber, A1
Arts, TH; Nouws, JF; Reekers-Ketting, JJ; Vree, TB1
Hekster, CA; van der Kleijn, E; Vree, TB1
Essers, L; Korte, H1
Gochin, R; Haigh, JM; Kanfer, I1
Damsma, JE; Friesen, WT; Hafkenscheid, JC; Hekster, YA; van Dalen, R; Vree, TB1
Agarwal, KC; Beylot, M; Brunengraber, H; David, F; Reider, M; Soloviev, MV; Tserng, KY; Zhang, Y1
Laizure, SC; Sanders, PL; Stein, DS; Stevens, RC1
Feng, WL; Gao, F; Ge, RL; Guan, W; Li, XY; Li, ZQ1
Luo, Y; Mao, D; Xu, B; Xu, L1
Li, XY; Li, YP; Liu, YN; Yuan, M; Zhu, JB1
Han, C; Liang, C; Liu, X; Zhao, F1

Trials

2 trial(s) available for n(4)-acetylsulfamethoxazole and sulfamethoxazole

ArticleYear
Use of low-dose trimethoprim-sulfamethoxazole thrice weekly for primary and secondary prophylaxis of Pneumocystis carinii pneumonia in human immunodeficiency virus-infected patients.
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:9

    Topics: Adult; Chromatography, High Pressure Liquid; Complement C4; Drug Administration Schedule; Female; HIV Infections; Humans; Leucovorin; Male; Pneumonia, Pneumocystis; Prospective Studies; Sulfamethoxazole; Trimethoprim; Zidovudine

1991
Comparison of the pharmacokinetics of sulfamethoxazole in male chinese volunteers at low altitude and acute exposure to high altitude versus subjects living chronically at high altitude: an open-label, controlled, prospective study.
    Clinical therapeutics, 2009, Volume: 31, Issue:11

    Topics: Altitude; Anti-Infective Agents; Biotransformation; Blood Chemical Analysis; Blood Proteins; China; Erythrocytes; Humans; Hypoxia; Male; Prospective Studies; Protein Binding; Sulfamethoxazole; Young Adult

2009

Other Studies

23 other study(ies) available for n(4)-acetylsulfamethoxazole and sulfamethoxazole

ArticleYear
Renal and metabolic clearances of sulfamethoxazole in Mexican healthy subjects.
    Proceedings of the Western Pharmacology Society, 1992, Volume: 35

    Topics: Adult; Humans; Kidney; Male; Mexico; Reference Values; Sulfamethoxazole

1992
Rapid simultaneous determination of trimethoprim, sulphamethoxazole and acetylsulphamethoxazole in human plasma and urine by high-performance liquid chromatography.
    Journal of pharmaceutical and biomedical analysis, 1991, Volume: 9, Issue:6

    Topics: Chromatography, High Pressure Liquid; Humans; Sulfamethoxazole; Trimethoprim

1991
Pharmacokinetics and adverse effects of 20-mg/kg/day trimethoprim and 100-mg/kg/day sulfamethoxazole in healthy adult subjects.
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:9

    Topics: Administration, Oral; Adult; Chromatography, High Pressure Liquid; Half-Life; Humans; Male; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1991
Disposition of drugs in cystic fibrosis. I. Sulfamethoxazole and trimethoprim.
    Clinical pharmacology and therapeutics, 1991, Volume: 49, Issue:4

    Topics: Adult; Chromatography, High Pressure Liquid; Cystic Fibrosis; Female; Humans; Male; Metabolic Clearance Rate; Protein Binding; Sulfamethoxazole; Trimethoprim

1991
Sampling the lipogenic hepatic acetyl-CoA pool in vivo in the rat. Comparison of xenobiotic probe to values predicted from isotopomeric distribution in circulating lipids and measurement of lipogenesis and acetyl-CoA dilution.
    The Journal of biological chemistry, 1991, Jun-15, Volume: 266, Issue:17

    Topics: Acetates; Acetyl Coenzyme A; Animals; Chromatography, High Pressure Liquid; Fatty Acids; Isotope Labeling; Kinetics; Lipids; Lipoproteins, VLDL; Male; Mass Spectrometry; Models, Biological; Rats; Rats, Inbred Strains; Sulfamethoxazole; Triglycerides; Xenobiotics

1991
Ion-paired high-performance liquid chromatographic separation of trimethoprim, sulfamethoxazole and N4-acetylsulfamethoxazole with solid-phase extraction.
    Journal of chromatography, 1990, Jun-08, Volume: 528, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Chromatography, High Pressure Liquid; Humans; Pneumonia, Pneumocystis; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1990
Acetylation, deacetylation and hydroxylation of sulphamethoxazole and N4-acetylsulphamethoxazole in the snail Cepaea hortensis.
    The veterinary quarterly, 1987, Volume: 9, Issue:4

    Topics: Acetylation; Animals; Chemical Phenomena; Chemistry; Hydroxylation; Snails; Sulfamethoxazole

1987
Acetylation, deacetylation and hydroxylation of sulphamethoxazole and N4-acetylsulphamethoxazole in the turtle Pseudemys scripta elegans.
    The veterinary quarterly, 1987, Volume: 9, Issue:4

    Topics: Acetylation; Animals; Chemical Phenomena; Chemistry; Hydroxylation; Sulfamethoxazole; Turtles

1987
Pharmacokinetics of the trimethoprim-sulphamethoxazole combination in the elderly.
    British journal of clinical pharmacology, 1985, Volume: 20, Issue:6

    Topics: Acetylation; Adult; Aged; Aging; Biological Availability; Blood Proteins; Drug Combinations; Female; Humans; Kinetics; Male; Protein Binding; Sulfamethoxazole; Time Factors; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1985
Excretion rates of sulfamethoxazole and N4-acetyl-sulfamethoxazole by fresh water turtles Pseudemys scripta elegans.
    The veterinary quarterly, 1984, Volume: 6, Issue:3

    Topics: Acetylation; Animals; Glomerular Filtration Rate; Kidney; Sulfamethoxazole; Turtles

1984
Acetylation of sulphamethoxazole by the snail Cepaea hortensis.
    Journal of veterinary pharmacology and therapeutics, 1984, Volume: 7, Issue:3

    Topics: Acetylation; Animals; Chromatography, High Pressure Liquid; Snails; Sulfamethoxazole

1984
Determination of trimethoprim, sulphamethoxazole and its N4-acetyl metabolite in biological fluids by high-performance liquid chromatography.
    Journal of chromatography, 1983, May-13, Volume: 274

    Topics: Aged; Buffers; Chromatography, High Pressure Liquid; Drug Combinations; Female; Humans; Kinetics; Male; Solvents; Sulfamethoxazole; Time Factors; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1983
High-performance liquid chromatographic quantitation of trimethoprim, sulfamethoxazole, and N4-acetylsulfamethoxazole in body fluids.
    Journal of chromatography, 1983, Dec-09, Volume: 278, Issue:2

    Topics: Chromatography, High Pressure Liquid; Humans; Sulfamethoxazole; Trimethoprim

1983
Placental transfer and renal clearance of sulphamethoxazole and its metabolite N4-acetylsulphamethoxazole in a pregnant ewe.
    Journal of veterinary pharmacology and therapeutics, 1983, Volume: 6, Issue:1

    Topics: Animals; Female; Kidney; Maternal-Fetal Exchange; Metabolic Clearance Rate; Placenta; Pregnancy; Sheep; Sulfamethoxazole

1983
Significance of apparent half-lives of a metabolite with a higher elimination rate than its parent drug.
    Drug intelligence & clinical pharmacy, 1982, Volume: 16, Issue:2

    Topics: Diazepam; Glucuronates; Half-Life; Humans; Kidney Diseases; Metabolic Clearance Rate; Oxazepam; Pharmaceutical Preparations; Sulfamethoxazole

1982
Comparison of the conventional methods and high-performance liquid chromatography for the determination of trimethoprim, sulfamethoxazole and its metabolite in serum.
    Chemotherapy, 1982, Volume: 28, Issue:4

    Topics: Biological Assay; Chromatography, High Pressure Liquid; Drug Resistance, Microbial; Humans; Sulfamethoxazole; Trimethoprim

1982
Simultaneous determination of trimethoprim, sulphamethoxazole and N4-acetylsulphamethoxazole in serum and urine by high-performance liquid chromatography.
    Journal of chromatography, 1981, Apr-10, Volume: 223, Issue:1

    Topics: Chromatography, High Pressure Liquid; Humans; Reference Values; Sulfamethoxazole; Trimethoprim

1981
Renal excretion of sulphamethoxazole and its metabolite N4-acetylsulphamethoxazole in patients with impaired kidney function.
    Therapeutic drug monitoring, 1981, Volume: 3, Issue:2

    Topics: Acetylation; Biotransformation; Chromatography, High Pressure Liquid; Creatinine; Humans; Kidney Diseases; Kinetics; Metabolic Clearance Rate; Sulfamethoxazole

1981
Assay of the acetyl-CoA probe acetyl-sulfamethoxazole and of sulfamethoxazole by gas chromatography-mass spectrometry.
    Analytical biochemistry, 1993, Aug-01, Volume: 212, Issue:2

    Topics: Acetyl Coenzyme A; Animals; Deuterium; Fluorobenzenes; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Rats; Rats, Sprague-Dawley; Reference Standards; Sulfamethoxazole

1993
Multiple-dose pharmacokinetics of 12 milligrams of trimethoprim and 60 milligrams of sulfamethoxazole per kilogram of body weight per day in healthy volunteers.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:3

    Topics: Adult; Body Weight; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Male; Sulfamethoxazole; Trimethoprim, Sulfamethoxazole Drug Combination

1993
Sulfamethoxazole biodegradation and biotransformation in the water-sediment system of a natural river.
    Bioresource technology, 2011, Volume: 102, Issue:14

    Topics: Bacillus; Biodegradation, Environmental; Biotransformation; Colony Count, Microbial; Geologic Sediments; Half-Life; Humic Substances; Kinetics; Rivers; Sulfamethoxazole

2011
[Pharmacokinetics of sulfamethoxazole in healthy Han volunteers living at plain and in native Han and Tibetan healthy volunteers living at high altitude].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2011, Volume: 46, Issue:9

    Topics: Adult; Altitude; Anti-Infective Agents; Area Under Curve; Asian People; China; Chromatography, High Pressure Liquid; Erythrocytes; Humans; Hypoxia; Male; Protein Binding; Sulfamethoxazole; Tablets; Trimethoprim, Sulfamethoxazole Drug Combination; Young Adult

2011
Occurrence and human health risk assessment of pharmaceuticals and personal care products in real agricultural systems with long-term reclaimed wastewater irrigation in Beijing, China.
    Ecotoxicology and environmental safety, 2020, Mar-01, Volume: 190

    Topics: Agricultural Irrigation; Beijing; China; Cosmetics; Crops, Agricultural; Humans; Pharmaceutical Preparations; Risk Assessment; Soil Pollutants; Sulfamethoxazole; Triclosan; Wastewater

2020