Page last updated: 2024-09-05

n(4)-acetylsulfadimethoxine and sulfadimethoxine

n(4)-acetylsulfadimethoxine has been researched along with sulfadimethoxine in 12 studies

Compound Research Comparison

Studies
(n(4)-acetylsulfadimethoxine)
Trials
(n(4)-acetylsulfadimethoxine)
Recent Studies (post-2010)
(n(4)-acetylsulfadimethoxine)
Studies
(sulfadimethoxine)
Trials
(sulfadimethoxine)
Recent Studies (post-2010) (sulfadimethoxine)
140079313108

Protein Interaction Comparison

ProteinTaxonomyn(4)-acetylsulfadimethoxine (IC50)sulfadimethoxine (IC50)
5-hydroxytryptamine receptor 6Homo sapiens (human)1.339

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19905 (41.67)18.7374
1990's6 (50.00)18.2507
2000's1 (8.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arts, TH; Beneken Kolmer, EW; Shimoda, M; Vree, TB1
Agemura, H; Imamura, Y; Otagiri, M1
Imamura, Y; Maruyama, T; Nakamura, H; Otagiri, M; Takadate, A1
Imamura, Y; Nakamura, H; Otagiri, M1
Imamura, Y; Mori, H; Otagiri, M1
Ichibagase, H; Imamura, Y; Mori, H1
Fukuda, Y; Nagata, T1
Furusawa, N; Mukai, T1
Boom, SP; Russel, FG; Van Ginneken, CA; Vree, TB; Wouterse, AC1
Barker, SA; Thune, RL; Walker, CC1
Furusawa, N1
Chiesa, OA; Kijak, PJ; Li, H; Smith, ML1

Other Studies

12 other study(ies) available for n(4)-acetylsulfadimethoxine and sulfadimethoxine

ArticleYear
The role of plasma protein binding on the metabolism and renal excretion of sulphadimethoxine and its metabolite N4-acetylsulphadimethoxine in pigs.
    The veterinary quarterly, 1990, Volume: 12, Issue:2

    Topics: Acetylation; Animals; Blood Proteins; Creatinine; Female; Hydrogen-Ion Concentration; Kidney; Protein Binding; Sulfadimethoxine; Swine

1990
[Displacing effect of serum protein binding on intestinal absorption of sulfadimethoxine].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1989, Volume: 109, Issue:1

    Topics: Animals; Blood Proteins; In Vitro Techniques; Intestinal Absorption; Jejunum; Male; Protein Binding; Rabbits; Sulfadimethoxine

1989
Characterization of binding sites for sulfadimethoxine and its major metabolite, N4-acetylsulfadimethoxine, on human and rabbit serum albumin.
    Chemical & pharmaceutical bulletin, 1989, Volume: 37, Issue:2

    Topics: Animals; Binding Sites; Humans; Protein Binding; Rabbits; Serum Albumin; Sulfadimethoxine; Sulfamonomethoxine; Sulfanilamides

1989
Effect of phenylbutazone on serum protein binding and pharmacokinetic behavior of sulfadimethoxine in rabbits, dogs and rats.
    Journal of pharmacobio-dynamics, 1989, Volume: 12, Issue:4

    Topics: Animals; Blood Proteins; Dogs; Drug Interactions; Male; Phenylbutazone; Protein Binding; Rabbits; Rats; Rats, Inbred Strains; Serum Albumin; Species Specificity; Sulfadimethoxine

1989
Contribution of N4-acetylsulfadimethoxine to the interaction of sulfadimethoxine with ketoprofen in rabbits.
    Chemical & pharmaceutical bulletin, 1987, Volume: 35, Issue:3

    Topics: Animals; Drug Interactions; Ketoprofen; Kinetics; Male; Phenylpropionates; Rabbits; Sulfadimethoxine

1987
Effect of simultaneous administration of drugs on absorption and excretion. XV. Effect of probenecid on plasma protein binding of sulfadimethoxine in rabbits: the role of N4-acetylsulfadimethoxine, the major metabolite of sulfadimethoxine.
    Chemical & pharmaceutical bulletin, 1983, Volume: 31, Issue:1

    Topics: Animals; Blood Proteins; Male; Probenecid; Protein Binding; Rabbits; Sulfadimethoxine

1983
Distribution and elimination of sulphadimethoxine and its metabolites in treated chicken.
    The Journal of pharmacy and pharmacology, 1994, Volume: 46, Issue:12

    Topics: Animals; Chickens; Chromatography, High Pressure Liquid; Chromatography, Liquid; Digestive System; Drug Residues; Gallbladder; Kidney; Liver; Lung; Male; Mass Spectrometry; Muscles; Myocardium; Skin; Spleen; Sulfadimethoxine; Tissue Distribution

1994
Simultaneous high-performance liquid chromatographic determination of residual sulphamonomethoxine, sulphadimethoxine and their N4-acetyl metabolites in foods of animal origin.
    Journal of chromatography. A, 1994, Aug-12, Volume: 677, Issue:1

    Topics: Animals; Cattle; Chickens; Chromatography, High Pressure Liquid; Drug Residues; Eggs; Food Analysis; Hydrogen-Ion Concentration; Indicators and Reagents; Meat; Sulfadimethoxine; Sulfamonomethoxine; Swine

1994
Renal tubular excretion of the N4-acetyl metabolites of sulphasomidine and sulphadimethoxine in the dog.
    The Journal of pharmacy and pharmacology, 1993, Volume: 45, Issue:7

    Topics: Acetylation; Animals; Chromatography, High Pressure Liquid; Dogs; Glomerular Filtration Rate; Injections, Intravenous; Kidney Tubules; Male; Protein Binding; Regression Analysis; Sulfadimethoxine; Sulfisomidine

1993
Plasma/muscle ratios of sulfadimethoxine residues in channel catfish (Ictalurus punctatus).
    Journal of veterinary pharmacology and therapeutics, 1995, Volume: 18, Issue:4

    Topics: Animals; Anti-Infective Agents; Aquaculture; Chromatography, High Pressure Liquid; Drug Residues; Female; Ictaluridae; Male; Muscles; Sulfadimethoxine

1995
Elimination half-lives of sulphadimethoxine and its N4-acetyl metabolite in tissues of laying hens.
    Zentralblatt fur Veterinarmedizin. Reihe A, 1999, Volume: 46, Issue:1

    Topics: Animals; Anti-Infective Agents; Biotransformation; Chickens; Female; Half-Life; Liver; Muscle, Skeletal; Ovary; Oviposition; Sulfadimethoxine; Tissue Distribution

1999
Determination of sulfadimethoxine and 4N-acetylsulfadimethoxine in bovine plasma, urine, oral fluid, and kidney and liver biopsy samples obtained surgically from standing animals by LC/MS/MS.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009, Jan-15, Volume: 877, Issue:3

    Topics: Animals; Cattle; Chromatography, Liquid; Drug Stability; Kidney; Linear Models; Liver; Reproducibility of Results; Saliva; Sensitivity and Specificity; Solid Phase Extraction; Sulfadimethoxine; Tandem Mass Spectrometry

2009