n(2),3-ethenoguanine has been researched along with guanine in 22 studies
| Studies (n(2),3-ethenoguanine) | Trials (n(2),3-ethenoguanine) | Recent Studies (post-2010) (n(2),3-ethenoguanine) | Studies (guanine) | Trials (guanine) | Recent Studies (post-2010) (guanine) |
|---|---|---|---|---|---|
| 25 | 0 | 5 | 16,278 | 822 | 4,809 |
| Protein | Taxonomy | n(2),3-ethenoguanine (IC50) | guanine (IC50) |
|---|---|---|---|
| Purine nucleoside phosphorylase | Homo sapiens (human) | 5 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (9.09) | 18.7374 |
| 1990's | 9 (40.91) | 18.2507 |
| 2000's | 5 (22.73) | 29.6817 |
| 2010's | 6 (27.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ludlum, DB; Matijasevic, Z; Sekiguchi, M | 1 |
| Kuśmierek, JT; Mroczkowska, MM | 1 |
| Cahill, DS; Cheng, KC; Dosanjh, MK; Loeb, LA; Preston, BD; Singer, B | 1 |
| Chavez, F; Dosanjh, MK; Folkman, W; Kuśmierek, JT; Singer, B | 1 |
| Adler, S; Doerjer, G; Oesch, F; Rettelbach, R | 1 |
| Doerjer, G; Oesch, F | 1 |
| Guengerich, FP; Humphreys, WG; Okazaki, O; Persmark, M; Raney, VM | 1 |
| Chenna, A; Dosanjh, MK; Fraenkel-Conrat, H; Kim, E; Samson, L; Singer, B | 1 |
| Charles, MJ; Christova-Gueoguieva, NI; Holt, S; Scheller, N; Swenberg, JA; Yen, TY | 1 |
| Ranasinghe, A; Scheller, N; Swenberg, JA; Upton, PB; Wu, KY | 1 |
| Ham, AJ; Johnson, F; Morinello, EJ; Nakamura, J; Ranasinghe, A; Swenberg, JA; Upton, PB | 1 |
| Ham, AJ; Morinello, EJ; Ranasinghe, A; Sangaiah, R; Swenberg, JA | 1 |
| Koc, H; Morinello, EJ; Ranasinghe, A; Swenberg, JA | 1 |
| Ham, AJ; Morinello, EJ; Nakamura, J; Ranasinghe, A; Swenberg, JA; Upton, PB | 1 |
| Gros, L; Ishchenko, AA; Saparbaev, M | 1 |
| He, C; Mishina, Y; Yang, CG | 1 |
| Collins, LB; Daye, LR; Evansky, P; Hatch, G; Mutlu, E; Stout, MD; Swenberg, JA; Upton, PB; Winsett, D | 1 |
| Lee, SL; Sahu, PK; Srinivasadesikan, V | 1 |
| Christov, PP; Egli, M; Guengerich, FP; Kozekov, ID; Pallan, PS; Pence, MG; Rizzo, CJ; Zhao, L | 1 |
| Choi, JY; Christov, PP; Egli, M; Guengerich, FP; Pence, MG; Rizzo, CJ; Wawrzak, Z; Zhao, L | 1 |
| Januar, LA; Molinski, TF | 1 |
| Chang, SC; Christov, PP; Delaney, JC; Drennan, CL; Essigmann, JM; Fedeles, BI; Guengerich, FP; Jost, M; Levine, SS; Li, D; Marnett, LJ; Rizzo, CJ; Singh, V; Wu, J; Yau, E; Zhao, L | 1 |
2 review(s) available for n(2),3-ethenoguanine and guanine
| Article | Year |
|---|---|
Mechanisms of formation of 1,N6-ethenoadenine, 3,N4-ethenocytosine, 1,N2-ethenoguanine and N2,3-ethenoguanine DNA adducts from substituted oxiranes.
Topics: Adenine; Cytosine; DNA Adducts; Ethylene Oxide; Guanine; Guanosine; Mutagens | 1994 |
Enzymology of repair of etheno-adducts.
Topics: Adenine; Animals; Cytosine; DNA Adducts; DNA Damage; DNA Glycosylases; DNA Repair; Guanine; Humans; Lipid Peroxidation; Reactive Oxygen Species; Thymine DNA Glycosylase | 2003 |
20 other study(ies) available for n(2),3-ethenoguanine and guanine
| Article | Year |
|---|---|
Release of N2,3-ethenoguanine from chloroacetaldehyde-treated DNA by Escherichia coli 3-methyladenine DNA glycosylase II.
Topics: Acetaldehyde; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Deoxyguanine Nucleotides; DNA; DNA Glycosylases; DNA Repair; Escherichia coli; Guanine; Kinetics; Methylnitrosourea; N-Glycosyl Hydrolases; Time Factors; Tritium | 1992 |
Miscoding potential of N2,3-ethenoguanine studied in an Escherichia coli DNA-dependent RNA polymerase in vitro system and possible role of this adduct in vinyl chloride-induced mutagenesis.
Topics: DNA Damage; DNA-Directed RNA Polymerases; Escherichia coli; Guanine; Hydrogen Bonding; Magnesium; Manganese; Mutagenesis; Poly C; Vinyl Chloride | 1991 |
The vinyl chloride DNA derivative N2,3-ethenoguanine produces G----A transitions in Escherichia coli.
Topics: Adenine; Base Composition; Base Sequence; DNA Polymerase II; DNA Replication; DNA, Bacterial; Escherichia coli; Guanine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutagens; Oligodeoxyribonucleotides; Uracil; Vinyl Chloride | 1991 |
Evidence for the mutagenic potential of the vinyl chloride induced adduct, N2, 3-etheno-deoxyguanosine, using a site-directed kinetic assay.
Topics: Base Composition; Chromatography, High Pressure Liquid; Deoxyguanine Nucleotides; DNA; Guanine; Guanosine; Kinetics; Mutagens; Phosphorus Radioisotopes; Polynucleotide 5'-Hydroxyl-Kinase; Thymidine; Vinyl Chloride | 1991 |
Repair of etheno DNA adducts by N-glycosylases.
Topics: Acetaldehyde; Adenine; Adenosine; DNA Glycosylases; DNA Repair; Guanine; Guanosine; N-Glycosyl Hydrolases; Substrate Specificity | 1986 |
Detection of N2,3-ethanoguanine in DNA after treatment with chloroacetaldehyde in vitro.
Topics: Acetaldehyde; Alkylation; Animals; DNA; Guanine; Salmon; Vinyl Chloride | 1982 |
All four known cyclic adducts formed in DNA by the vinyl chloride metabolite chloroacetaldehyde are released by a human DNA glycosylase.
Topics: Acetaldehyde; Adenine; Animals; Base Sequence; Cattle; Cytosine; DNA; DNA Glycosylases; DNA-Binding Proteins; Guanine; HeLa Cells; Humans; Molecular Sequence Data; N-Glycosyl Hydrolases; Oligonucleotide Probes | 1994 |
Quantitative analysis of the DNA adduct N2,3-ethenoguanine using liquid chromatography/electrospray ionization mass spectrometry.
Topics: Animals; Cattle; Chromatography, Liquid; DNA Adducts; Guanine; Humans; Male; Mass Spectrometry; Rats; Rats, Sprague-Dawley | 1996 |
Application of gas chromatography/electron capture negative chemical ionization high-resolution mass spectrometry for analysis of DNA and protein adducts.
Topics: Animals; Calibration; DNA Adducts; Gas Chromatography-Mass Spectrometry; Guanine; Humans; Indicators and Reagents; Proteins; Rats; Valine | 1998 |
Immunoaffinity/gas chromatography/high-resolution mass spectrometry method for the detection of N(2),3-ethenoguanine.
Topics: Animals; Carcinogens; Cattle; Chromatography, Affinity; Chromatography, High Pressure Liquid; DNA; DNA Adducts; DNA Damage; Gas Chromatography-Mass Spectrometry; Guanine; Liver; Rats; Sensitivity and Specificity; Vinyl Compounds | 1999 |
Simultaneous quantitation of N(2),3-ethenoguanine and 1,N(2)-ethenoguanine with an immunoaffinity/gas chromatography/high-resolution mass spectrometry assay.
Topics: Animals; Antibodies; Cell Transformation, Neoplastic; DNA Adducts; Gas Chromatography-Mass Spectrometry; Guanine; Immunoassay; Male; Oxidation-Reduction; Rabbits; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Vinyl Chloride | 2001 |
Differential induction of N(2),3-ethenoguanine in rat brain and liver after exposure to vinyl chloride.
Topics: Administration, Inhalation; Age Factors; Animals; Brain; Carbon Isotopes; Carcinogens; DNA; DNA Adducts; Dose-Response Relationship, Drug; Gas Chromatography-Mass Spectrometry; Guanine; Liver; Male; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Vinyl Chloride | 2002 |
Molecular dosimetry and repair of N(2),3-ethenoguanine in rats exposed to vinyl chloride.
Topics: Administration, Inhalation; Age Factors; Animals; Carcinogens; DNA Adducts; DNA Repair; Dose-Response Relationship, Drug; Gas Chromatography-Mass Spectrometry; Guanine; Hepatocytes; Liver; Male; Rats; Rats, Sprague-Dawley; Vinyl Chloride | 2002 |
Direct repair of the exocyclic DNA adduct 1,N6-ethenoadenine by the DNA repair AlkB proteins.
Topics: Adenine; AlkB Homolog 3, Alpha-Ketoglutarate-Dependent Dioxygenase; Alkylation; Cytosine; Dioxygenases; DNA; DNA Adducts; DNA Repair; DNA Repair Enzymes; DNA-Binding Proteins; Escherichia coli Proteins; Guanine; Humans; Hydrogen-Ion Concentration; Iron; Mixed Function Oxygenases; Molecular Structure; Time Factors | 2005 |
Development and application of an LC-MS/MS method for the detection of the vinyl chloride-induced DNA adduct N(2),3-ethenoguanine in tissues of adult and weanling rats following exposure to [(13)C(2)]-VC.
Topics: Animals; Carbon Isotopes; Carcinogens; Chromatography, High Pressure Liquid; DNA Adducts; Guanine; Half-Life; Kidney; Liver; Lung; Male; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Vinyl Chloride | 2010 |
Model calculations for the misincorporation of nucleotides opposite five-membered exocyclic DNA adduct: N(2),3-ethenoguanine.
Topics: Animals; DNA Adducts; DNA Damage; Guanine; Hydrogen Bonding; Mathematical Computing; Models, Chemical; Mutagenesis; Nucleotides; Rats | 2011 |
Replication of N2,3-ethenoguanine by DNA polymerases.
Topics: DNA Adducts; DNA Replication; DNA-Directed DNA Polymerase; Guanine; Humans; Mutation; Oxidative Stress; Protein Conformation; Vinyl Chloride | 2012 |
Basis of miscoding of the DNA adduct N2,3-ethenoguanine by human Y-family DNA polymerases.
Topics: Cell-Free System; DNA Adducts; DNA Polymerase beta; DNA-Directed DNA Polymerase; Guanine; Humans; Nuclear Proteins; Nucleotidyltransferases | 2012 |
Acremolin from Acremonium strictum is N(2),3-etheno-2'-isopropyl-1-methylguanine, not a 1H-azirine. Synthesis and structural revision.
Topics: Acremonium; Biological Products; Fluorescent Dyes; Guanine; Molecular Structure; Purines | 2013 |
Next-generation sequencing reveals the biological significance of the N(2),3-ethenoguanine lesion in vivo.
Topics: Dioxygenases; DNA Adducts; DNA Damage; DNA Polymerase beta; DNA Repair; DNA Repair Enzymes; Guanine; High-Throughput Nucleotide Sequencing; Mutagenesis; Mutation; Sequence Analysis, DNA; Sequence Deletion | 2015 |