n(1),n(8)-diethylspermidine has been researched along with spermidine in 8 studies
| Studies (n(1),n(8)-diethylspermidine) | Trials (n(1),n(8)-diethylspermidine) | Recent Studies (post-2010) (n(1),n(8)-diethylspermidine) | Studies (spermidine) | Trials (spermidine) | Recent Studies (post-2010) (spermidine) |
|---|---|---|---|---|---|
| 10 | 0 | 0 | 5,643 | 28 | 1,281 |
| Protein | Taxonomy | n(1),n(8)-diethylspermidine (IC50) | spermidine (IC50) |
|---|---|---|---|
| Pyruvate kinase PKM | Homo sapiens (human) | 1.41 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (62.50) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bergeron, RJ; Dimova, H; Feng, Y; McManis, JS; Phanstiel, O; Porter, C; Raisler, B; Weimar, WR | 1 |
| Basu, HS; Coffino, P; Ghoda, L; Marton, LJ; Porter, CW | 1 |
| Beerman, TA; Bergeron, RJ; Kelly, EJ; Porter, CW; Vertino, PM | 1 |
| Casero, RA; Denstman, SC; Ervin, SJ | 1 |
| Berger, FG; Bergeron, RJ; Ganis, B; Pegg, AE; Porter, CW | 1 |
| Baylin, SB; Casero, RA; Go, B; Luk, GD; Smith, J; Theiss, HW | 1 |
| Bergeron, RJ; Ganis, B; Kramer, DL; Marton, LJ; Porter, CW; Vinson, T | 1 |
| Bergeron, RJ; Casero, RA; McManis, J; Porter, CW | 1 |
8 other study(ies) available for n(1),n(8)-diethylspermidine and spermidine
| Article | Year |
|---|---|
A comparison of structure-activity relationships between spermidine and spermine analogue antineoplastics.
Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Cell Division; Leukemia L1210; Magnetic Resonance Spectroscopy; Ornithine Decarboxylase; Polyamines; Spermidine; Spermine; Tumor Cells, Cultured | 1997 |
Role of ornithine decarboxylase suppression and polyamine depletion in the antiproliferative activity of polyamine analogs.
Topics: Adenosylmethionine Decarboxylase; Animals; Biogenic Polyamines; Cell Division; CHO Cells; Cricetinae; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Spermidine; Spermine; Transfection; Trypanosoma | 1992 |
Selective cellular depletion of mitochondrial DNA by the polyamine analog N1,N12-bis(ethyl)spermine and its relationship to polyamine structure and function.
Topics: Animals; Antineoplastic Agents; Blotting, Southern; Cell Division; Cell Line, Transformed; DNA; DNA Damage; DNA, Mitochondrial; DNA, Neoplasm; DNA, Superhelical; Electrophoresis, Agar Gel; Fibroblasts; Leukemia L1210; Mice; Polyamines; Spermidine; Spermine; Structure-Activity Relationship; Time Factors | 1991 |
Comparison of the effects of treatment with the polyamine analogue N1,N8 bis(ethyl)spermidine (BESpd) or difluoromethylornithine (DFMO) on the Topoisomerase II mediated formation of 4'-(9-acridinylamino) methanesulfon-m-anisidide (m-AMSA) induced cleavabl
Topics: Amsacrine; Chemical Precipitation; DNA Topoisomerases, Type II; DNA, Neoplasm; Eflornithine; Humans; Lung Neoplasms; Polyamines; Spermidine; Tumor Cells, Cultured | 1987 |
Regulation of ornithine decarboxylase activity by spermidine and the spermidine analogue N1N8-bis(ethyl)spermidine.
Topics: Adenosylmethionine Decarboxylase; Animals; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Cycloheximide; Kinetics; Mice; Ornithine Decarboxylase; Polyamines; Proteins; S-Adenosylmethionine; Spermidine | 1987 |
Cytotoxic response of the relatively difluoromethylornithine-resistant human lung tumor cell line NCI H157 to the polyamine analogue N1,N8-bis(ethyl)spermidine.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Division; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance; Eflornithine; Humans; Lung Neoplasms; Ornithine Decarboxylase Inhibitors; Polyamines; Spermidine | 1987 |
Comparison and characterization of growth inhibition in L1210 cells by alpha-difluoromethylornithine, an inhibitor of ornithine decarboxylase, and N1,N8-bis(ethyl)spermidine, an apparent regulator of the enzyme.
Topics: Adenosylmethionine Decarboxylase; Alkynes; Animals; Cells, Cultured; Diamines; Eflornithine; Leukemia L1210; Ornithine Decarboxylase Inhibitors; Polyamines; Spermidine | 1986 |
Relative abilities of bis(ethyl) derivatives of putrescine, spermidine, and spermine to regulate polyamine biosynthesis and inhibit L1210 leukemia cell growth.
Topics: Adenosylmethionine Decarboxylase; Animals; Biological Transport; Cell Division; Leukemia L1210; Mice; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Spermine; Structure-Activity Relationship | 1987 |