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n(1),n(14)-bis(ethyl)homospermine and n(1),n(11)-diethylnorspermine

n(1),n(14)-bis(ethyl)homospermine has been researched along with n(1),n(11)-diethylnorspermine in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's9 (69.23)18.2507
2000's3 (23.08)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bergeron, RJ; Feng, Y; Kramer, D; Liu, CZ; Luchetta, GR; McManis, JS; Ortiz-Ocasio, J; Vinson, JR; Weimar, WR; Wu, Q1
Bergeron, RJ; Feng, Y; Gao, F; Raisler, B; Sninsky, CA; Weimar, WR; Wu, Q; Yao, GW; Yao, H1
Bergeron, RJ; Feng, Y; McManis, JS; Weimar, WR; Wu, Q1
Bergeron, RJ; McCosar, BH; Müller, R; Smith, RE; Weimar, WR; Yao, H; Zimmerman, CO1
Bergeron, RJ; Bussenius, J; McManis, JS; Merriman, RL; Müller, R; Smith, RE; Weimar, WR; Yao, H1
Casero, RA; Woster, PM2
Bergeron, RJ; Bernacki, RJ; Porter, CW1
Bergeron, RJ; Chang, BK; Liang, Y; Porter, CW1
Bergeron, RJ; Chang, BK; Liang, Y; Libby, PR; Porter, CW; Vinson, JR1
Beck, DE; Bergeron, RJ; Hawthorne, TR; Ingeno, MJ; Vinson, JR1
Bergeron, RJ; Chang, BK; Liang, Y; Miller, DW; Porter, CW; Wang, G1
Bergeron, RJ; Katovich, MJ; Sninsky, CA; Wiegand, J1

Reviews

2 review(s) available for n(1),n(14)-bis(ethyl)homospermine and n(1),n(11)-diethylnorspermine

ArticleYear
Terminally alkylated polyamine analogues as chemotherapeutic agents.
    Journal of medicinal chemistry, 2001, Jan-04, Volume: 44, Issue:1

    Topics: Animals; Antineoplastic Agents; Antiparasitic Agents; Apoptosis; Biological Transport; Drug Screening Assays, Antitumor; Humans; Opportunistic Infections; Polyamines; Reactive Oxygen Species; Structure-Activity Relationship; Tubulin

2001
Recent advances in the development of polyamine analogues as antitumor agents.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Animals; Antineoplastic Agents; Biogenic Polyamines; Breast Neoplasms; DNA; Drug Discovery; Eflornithine; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Histone Demethylases; Homeostasis; Humans; Oxidoreductases, N-Demethylating; Polyamines; Structure-Activity Relationship

2009

Other Studies

11 other study(ies) available for n(1),n(14)-bis(ethyl)homospermine and n(1),n(11)-diethylnorspermine

ArticleYear
Antiproliferative properties of polyamine analogues: a structure-activity study.
    Journal of medicinal chemistry, 1994, Oct-14, Volume: 37, Issue:21

    Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Animals; Binding, Competitive; Cell Division; Leukemia L1210; Mice; Molecular Structure; Ornithine Decarboxylase Inhibitors; Polyamines; Spermidine; Spermine; Structure-Activity Relationship

1994
Metabolically programmed polyamine analogue antidiarrheals.
    Journal of medicinal chemistry, 1996, Jun-21, Volume: 39, Issue:13

    Topics: Animals; Antidiarrheals; Biological Transport; Castor Oil; Cell Division; Computer Simulation; Diarrhea; Drug Design; Female; Kidney; Leukemia L1210; Liver; Male; Mice; Models, Chemical; Molecular Structure; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermine; Tumor Cells, Cultured

1996
Polyamine analogue regulation of NMDA MK-801 binding: a structure-activity study.
    Journal of medicinal chemistry, 1996, Dec-20, Volume: 39, Issue:26

    Topics: Animals; Cerebral Cortex; Dizocilpine Maleate; Magnetic Resonance Spectroscopy; Male; Protons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermine; Structure-Activity Relationship

1996
Effect of polyamine analogues on hypusine content in JURKAT T-cells.
    Journal of medicinal chemistry, 1998, Sep-24, Volume: 41, Issue:20

    Topics: Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Biological Transport; Cell Division; Chromatography, High Pressure Liquid; Dansyl Compounds; Enzyme Inhibitors; Humans; Jurkat Cells; Leukemia L1210; Lysine; Ornithine Decarboxylase Inhibitors; Spermidine; Spermine; Tumor Cells, Cultured

1998
Synthesis and evaluation of hydroxylated polyamine analogues as antiproliferatives.
    Journal of medicinal chemistry, 2000, Jan-27, Volume: 43, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Division; Hydroxylation; Leukemia L1210; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Polyamines; Tumor Cells, Cultured

2000
Antitumor activity of N,N'-bis(ethyl)spermine homologues against human MALME-3 melanoma xenografts.
    Cancer research, 1992, May-01, Volume: 52, Issue:9

    Topics: Acetyltransferases; Animals; Cell Division; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Screening Assays, Antitumor; Enzyme Induction; Female; Humans; Melanoma; Mice; Mice, Nude; Spermine; Transplantation, Heterologous; Tumor Cells, Cultured

1992
Antitumor effects of N-alkylated polyamine analogues in human pancreatic adenocarcinoma models.
    Cancer chemotherapy and pharmacology, 1992, Volume: 30, Issue:3

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Humans; Male; Mice; Mice, Nude; Neoplasm Transplantation; Pancreatic Neoplasms; Spermine; Tumor Cells, Cultured

1992
Regulatory and antiproliferative effects of N-alkylated polyamine analogues in human and hamster pancreatic adenocarcinoma cell lines.
    Cancer chemotherapy and pharmacology, 1992, Volume: 30, Issue:3

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cricetinae; Humans; Mesocricetus; Pancreatic Neoplasms; Spermine; Tumor Cells, Cultured

1992
Role of the methylene backbone in the antiproliferative activity of polyamine analogues on L1210 cells.
    Cancer research, 1989, Jun-01, Volume: 49, Issue:11

    Topics: Animals; Antineoplastic Agents; Binding, Competitive; Cell Division; Cell Survival; DNA, Neoplasm; Leukemia L1210; Mice; Spermine; Structure-Activity Relationship; Tumor Cells, Cultured

1989
Effects of diethyl spermine analogues in human bladder cancer cell lines in culture.
    The Journal of urology, 1993, Volume: 150, Issue:4

    Topics: Carcinoma, Transitional Cell; Drug Screening Assays, Antitumor; Eflornithine; Humans; In Vitro Techniques; Spermine; Tumor Cells, Cultured; Urinary Bladder Neoplasms

1993
The impact of polyamine analogues on the blood pressure of normotensive and hypertensive rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 1995, Volume: 17, Issue:8

    Topics: Amines; Animals; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Wistar; Spermine

1995