n(1),n(14)-bis(ethyl)homospermine and n(1), n(12)-diethylspermine

n(1),n(14)-bis(ethyl)homospermine has been researched along with n(1), n(12)-diethylspermine in 10 studies

Research

Studies (10)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (20.00)	18.7374
1990's	5 (50.00)	18.2507
2000's	3 (30.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Austin, JK; Bergeron, RJ; McManis, JS; Weimar, WR; Wu, Q	1
Bergeron, RJ; Feng, Y; Kramer, D; Liu, CZ; Luchetta, GR; McManis, JS; Ortiz-Ocasio, J; Vinson, JR; Weimar, WR; Wu, Q	1
Bergeron, RJ; Feng, Y; Gao, F; Raisler, B; Sninsky, CA; Weimar, WR; Wu, Q; Yao, GW; Yao, H	1
Bergeron, RJ; Feng, Y; McManis, JS; Weimar, WR; Wu, Q	1
Casero, RA; Woster, PM	2
Algee, SE; Bergeron, RJ; Fannin, TL; McManis, JS; Slusher, MA; Smith, RE; Snyder, PS; Weimar, WR; Wiegand, J	1
Bergeron, RJ; Bernacki, RJ; Porter, CW	1
Baylin, SB; Bergeron, RJ; Casero, RA; Celano, P; Ervin, SJ	1
Beck, DE; Bergeron, RJ; Hawthorne, TR; Ingeno, MJ; Vinson, JR	1

Reviews

2 review(s) available for n(1),n(14)-bis(ethyl)homospermine and n(1), n(12)-diethylspermine

Article	Year
Terminally alkylated polyamine analogues as chemotherapeutic agents. Journal of medicinal chemistry, 2001, Jan-04, Volume: 44, Issue:1 Topics: Animals; Antineoplastic Agents; Antiparasitic Agents; Apoptosis; Biological Transport; Drug Screening Assays, Antitumor; Humans; Opportunistic Infections; Polyamines; Reactive Oxygen Species; Structure-Activity Relationship; Tubulin	2001
Recent advances in the development of polyamine analogues as antitumor agents. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Animals; Antineoplastic Agents; Biogenic Polyamines; Breast Neoplasms; DNA; Drug Discovery; Eflornithine; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Histone Demethylases; Homeostasis; Humans; Oxidoreductases, N-Demethylating; Polyamines; Structure-Activity Relationship	2009

Article

Year

Terminally alkylated polyamine analogues as chemotherapeutic agents.

Journal of medicinal chemistry, 2001, Jan-04, Volume: 44, Issue:1

Topics: Animals; Antineoplastic Agents; Antiparasitic Agents; Apoptosis; Biological Transport; Drug Screening Assays, Antitumor; Humans; Opportunistic Infections; Polyamines; Reactive Oxygen Species; Structure-Activity Relationship; Tubulin

2001

Recent advances in the development of polyamine analogues as antitumor agents.

Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

Topics: Animals; Antineoplastic Agents; Biogenic Polyamines; Breast Neoplasms; DNA; Drug Discovery; Eflornithine; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Histone Demethylases; Homeostasis; Humans; Oxidoreductases, N-Demethylating; Polyamines; Structure-Activity Relationship

2009

Other Studies

8 other study(ies) available for n(1),n(14)-bis(ethyl)homospermine and n(1), n(12)-diethylspermine

Article	Year
Impact of polyamine analogues on the NMDA receptor. Journal of medicinal chemistry, 1995, Feb-03, Volume: 38, Issue:3 Topics: Animals; Binding Sites; Cerebral Cortex; Dizocilpine Maleate; Male; Polyamines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate	1995
Antiproliferative properties of polyamine analogues: a structure-activity study. Journal of medicinal chemistry, 1994, Oct-14, Volume: 37, Issue:21 Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Animals; Binding, Competitive; Cell Division; Leukemia L1210; Mice; Molecular Structure; Ornithine Decarboxylase Inhibitors; Polyamines; Spermidine; Spermine; Structure-Activity Relationship	1994
Metabolically programmed polyamine analogue antidiarrheals. Journal of medicinal chemistry, 1996, Jun-21, Volume: 39, Issue:13 Topics: Animals; Antidiarrheals; Biological Transport; Castor Oil; Cell Division; Computer Simulation; Diarrhea; Drug Design; Female; Kidney; Leukemia L1210; Liver; Male; Mice; Models, Chemical; Molecular Structure; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermine; Tumor Cells, Cultured	1996
Polyamine analogue regulation of NMDA MK-801 binding: a structure-activity study. Journal of medicinal chemistry, 1996, Dec-20, Volume: 39, Issue:26 Topics: Animals; Cerebral Cortex; Dizocilpine Maleate; Magnetic Resonance Spectroscopy; Male; Protons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermine; Structure-Activity Relationship	1996
Polyamine analogue antidiarrheals: a structure-activity study. Journal of medicinal chemistry, 2001, Jan-18, Volume: 44, Issue:2 Topics: Administration, Oral; Animals; Antidiarrheals; Castor Oil; Cyclohexylamines; Diarrhea; Dogs; Female; Lethal Dose 50; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mice; Rats; Rats, Sprague-Dawley; Spermine; Structure-Activity Relationship; Tissue Distribution; Toxicity Tests, Acute	2001
Antitumor activity of N,N'-bis(ethyl)spermine homologues against human MALME-3 melanoma xenografts. Cancer research, 1992, May-01, Volume: 52, Issue:9 Topics: Acetyltransferases; Animals; Cell Division; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Screening Assays, Antitumor; Enzyme Induction; Female; Humans; Melanoma; Mice; Mice, Nude; Spermine; Transplantation, Heterologous; Tumor Cells, Cultured	1992
Differential response to treatment with the bis(ethyl)polyamine analogues between human small cell lung carcinoma and undifferentiated large cell lung carcinoma in culture. Cancer research, 1989, Feb-01, Volume: 49, Issue:3 Topics: Adenosylmethionine Decarboxylase; Carcinoma; Carcinoma, Small Cell; Cells, Cultured; Humans; Lung Neoplasms; Ornithine Decarboxylase Inhibitors; Spermine	1989
Role of the methylene backbone in the antiproliferative activity of polyamine analogues on L1210 cells. Cancer research, 1989, Jun-01, Volume: 49, Issue:11 Topics: Animals; Antineoplastic Agents; Binding, Competitive; Cell Division; Cell Survival; DNA, Neoplasm; Leukemia L1210; Mice; Spermine; Structure-Activity Relationship; Tumor Cells, Cultured	1989