n(1)-methylnicotinamide has been researched along with niacinamide in 226 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 92 (40.71) | 18.7374 |
| 1990's | 37 (16.37) | 18.2507 |
| 2000's | 23 (10.18) | 29.6817 |
| 2010's | 56 (24.78) | 24.3611 |
| 2020's | 18 (7.96) | 2.80 |
| Authors | Studies |
|---|---|
| Pontzer, NJ; Shaikh, B | 1 |
| Johansson-Brittebo, E; Tjälve, H | 1 |
| Rumrich, G; Ullrich, KJ | 1 |
| Aranda, A; Sánchez-Pacheco, A | 1 |
| Dennis, MF; Stratford, MR | 1 |
| Ballardie, FW; Daley-Yates, PT; Maïza, A; Waldek, S | 1 |
| Drevenstedt, B; Hoshino, J; Kröger, H; Schalge, S | 1 |
| Bender, DA; Njagi, EN | 1 |
| Griffiths, DA; Hall, SD; Sokol, PP | 1 |
| Giacomini, KM; Ott, RJ; Salgado, C; Yuan, G | 1 |
| Giacomini, KM; Hui, AC; Ott, RJ; Yuan, G | 1 |
| Fujimura, S; Kato, N; Miyazaki, M; Moriyama, Y; Nakagawa, K; Okui, K | 1 |
| Suzuki, T; Yuyama, S | 1 |
| Kewitz, H; Looby, M; Nitz, M; Toussaint, S; Weber, W | 1 |
| Cox, R; Kuykendall, JR | 2 |
| Besseghir, K; Chatton, JY; Roch-Ramel, F | 1 |
| Fauth, C; Fouda, AK; Roch-Ramel, F | 1 |
| Bendayan, R; Sellers, EM; Silverman, M | 1 |
| Besseghir, K; Mosig, D; Roch-Ramel, F | 1 |
| Giacomini, KM; Hai, AC; Ott, RJ | 1 |
| Gates, SB; Sokol, PP | 1 |
| Dekant, W; Gemborys, M; Rumrich, G; Ullrich, KJ | 1 |
| Daley-Yates, PT; Maiza, A | 1 |
| Daley-Yates, PT; Nasseri, K | 1 |
| Johnson, TR; Morrissette, J; Moseley, RH | 1 |
| Clemens, RA; Fu, CS; Jacob, RA; McKee, RW; Swendseid, ME | 1 |
| Carpenter, KJ; Schelstraete, M | 1 |
| Holohan, PD; Huiatt, KR; Ross, CR; Sokol, PP | 1 |
| Hayashi, K; Kobayashi, K; Une, H | 1 |
| Holohan, PD; Ross, CR; Sokol, PP | 3 |
| Grahn, H; Grätz, R; Kröger, H | 2 |
| Hanski, C; Lawley, PD | 1 |
| Brokl, OH; Dantzler, WH | 1 |
| Banks, RB; Cooke, RT | 1 |
| Manganel, M; Rafizadeh, C; Roch-Ramel, F; Schäli, C | 1 |
| Carpenter, KJ; Cook, NE | 1 |
| Giacomini, KM; Hsyu, PH | 1 |
| Holohan, PD; Miller, DS | 1 |
| Giacomini, KM; Gisclon, LG; Hsyu, PH; Hui, AC | 1 |
| Silverman, DN; Thomas, HG | 1 |
| Johnson, GS; Lucas, DL | 1 |
| Hanano, M; Iga, T; Sawada, Y; Shim, CK | 4 |
| Grätz, R; Kröger, H | 2 |
| Motooka, K; Murata, K; Shibata, K | 1 |
| Carpenter, KJ; Carter, EG | 1 |
| Carter, EG | 1 |
| Kuttesch, JF; Nelson, JA; Robins, MJ | 1 |
| Simon, M; Terry, RC | 1 |
| Jenden, DJ; Jope, RS; Kang-Lee, YA; McKee, RW; Swendseid, ME; Wright, SM | 1 |
| Falany, J; Fischer, LJ; Fisher, R | 1 |
| Forchette, CA; Patterson, JI | 1 |
| Bender, DA; Totoe, L | 1 |
| Streffer, C; Tamulevicius, P | 1 |
| Dantzler, WH; Hawk, CT | 1 |
| Sauberlich, HE | 1 |
| Hoshino, J; Kröger, H; Schlüter, U | 1 |
| Grunfeld, C; Shigenaga, JK | 1 |
| Barra, R; Kuhr, WG; Lea, MA; Randolph, V | 1 |
| Filetti, S; Rapoport, B; Takai, NA | 1 |
| Kubota, H; Nomura, K; Sano, K; Shin, M; Umezawa, C; Yamada, O | 1 |
| Anderson, RF | 1 |
| Clark, BR | 1 |
| Huang, SS; Pontzer, NJ; Shaikh, B | 1 |
| Bunting, JW; Laderoute, KR; Norris, DJ | 1 |
| Inoue, M; Ishida, T; Tomita, KI | 1 |
| Holohan, PD; Ross, CR | 1 |
| Johnson, GS | 1 |
| Egsgaard, H; Funck, J; Holmen, H; Larsen, E | 1 |
| Berndt, WO | 1 |
| Fraser, DR; Sandhu, JS | 1 |
| Chiang, PK; Johnson, GS | 1 |
| David, C; Rumrich, G; Ullrich, KJ | 1 |
| Bendayan, R; Lo, B; Silverman, M | 1 |
| Kobayashi, K; Miki, M; Nishino, T; Okamoto, K | 1 |
| Ballardie, FW; Chalmers, RJ; Daley-Yates, PT; Edwards, BD; Lawson, RS; Maiza, A; O'Driscoll, JB; Testa, HJ | 1 |
| David, C; Fritzsch, G; Rumrich, G; Ullrich, KJ | 2 |
| Fukushima, T; Hojo, N; Isobe, A; Shiwaku, K; Tawara, T; Yamane, Y | 1 |
| Jenden, DJ; Vargas, HM | 1 |
| O'Sullivan, PE; Tipton, KF | 1 |
| Chun, JK; Giacomini, KM; Lau, E; Piquette-Miller, M; Tong, LQ; Zhang, L | 1 |
| Kondo, T; Miki, A; Shibata, K | 1 |
| Bernier, J; Bieri, S; Bolla, M; Denekamp, J; Dennis, MF; Hagen, F; Kocagöncü, O; Rojas, A; Stratford, MR | 1 |
| Pritchard, JB; Sweet, DH | 1 |
| Floreani, M; Napoli, E; Orlando, R; Padrini, R; Palatini, P | 1 |
| Iinuma, F; Mawatari, K; Watanabe, M | 1 |
| Decker, RW; Malejka-Giganti, D; Ritter, CL | 1 |
| Bélaz, N; Biollaz, J; Decosterd, LA; Kesselring, UW; Musfeld, C | 1 |
| Daff, S; Kobayashi, K; Sagami, I; Shimizu, T; Tagawa, S | 1 |
| Fukushima, T; Kaetsu, A; Lim, H; Moriyama, M | 1 |
| Fukushima, T | 1 |
| DIETRICH, LS; ELVEHJEM, CA; MONSON, WJ | 1 |
| GOLDSMITH, GA; ROSENTHAL, HL; SARETT, HP | 1 |
| BARTOLOMEI, G; ROSSI, M | 1 |
| COLOWICK, SP; PULLMAN, ME | 1 |
| ROSENTHAL, HL | 2 |
| COLOWICK, SP; RAFTER, GW | 1 |
| HANKES, LV; URIVETSKY, M | 1 |
| ASAMI, T | 1 |
| DE BELLIS, E; ZARRILLI, L | 1 |
| CHALOUPKA, MM; REYNOLDS, MS; VIVIAN, VM | 1 |
| HUGGINS, CG; PETERS, L; RODRIGUEZ, GA; VOLLE, RL | 1 |
| ATTWOOD, WL; GREEN, RE; KOH, YS; PETERS, L; RICKER, WE | 1 |
| BROWN, RR; DECKER, RH; YESS, N | 1 |
| FARAH, A; FRAZER, M | 1 |
| STARSHOV, PD | 1 |
| MAINARDI, L; NICOLIS, FB; TENCONI, LT | 1 |
| HULL, JG; MARTIN, RB | 1 |
| PRICE, JM; REYNOLDS, MS; VIVIAN, VM | 1 |
| BECKS, H; RATCLIFF, P | 1 |
| CONSOLAZIO, CF; PLOUGH, IC | 1 |
| HEIMBERG, M; LEDER, IG; PERLZWEIG, WA; ROSEN, F | 1 |
| SUNG, SC; TUNG, TC | 1 |
| LIENER, IE; SCHULTZE, MO | 1 |
| BEYER, KH; RUSSO, HF | 1 |
| CARPENTER, KJ; KODICEK, E | 1 |
| Creeke, PI; Seal, AJ | 1 |
| Gebicki, J; Sysa-Jedrzejowska, A; Wieczorkowska, M; Wozniacka, A | 1 |
| Kitamura, S; Ohta, S; Shimomiya, K; Sugihara, K; Tayama, Y; Yoshimoto, D | 1 |
| El Barbary, RA; El Dawya, MA; Mabrouk, MM | 1 |
| Kitamura, S; Moriyasu, A; Ohta, S; Sugihara, K; Tayama, Y | 1 |
| Adamus, J; Bartus, M; Buczko, W; Chlopicki, S; Gebicki, J; Lomnicka, M; Mogielnicki, A; Swies, J | 1 |
| Cheung, E; Creeke, PI; Dibari, F; Kyroussis, E; Seal, AJ; van den Briel, T | 1 |
| Cox, R; Kinder, D; Kuykendall, JR | 1 |
| Biedron, R; Bryniarski, K; Chlopicki, S; Jakubowski, A; Marcinkiewicz, J | 1 |
| LEDER, IG; PERLZWEIG, WA; ROSEN, F | 1 |
| Horie, T; Inoue, T; Kitamura, S; Nitta, K; Ohta, S; Sugihara, K; Tanoue, C; Tayama, Y | 1 |
| Hirst, DG; Ruddock, MW | 1 |
| Lazarewicz, JW; Salinska, E; Slomka, M; Zieminska, E | 1 |
| Brzozowski, T; Chlopicki, S; Drozdowicz, D; Konturek, PC; Konturek, SJ; Kwiecien, S; Pajdo, R; Pawlik, M; Pawlik, WW; Ptak-Belowska, A; Sliwowski, Z; Slonimska, E | 1 |
| Lazarewicz, J; Slomka, M; Zieminska, E | 1 |
| GROSSMAN, WI; KNOX, WE | 2 |
| DU VIGNEAUD, V; KELLER, EB; WOOD, JL | 1 |
| Dragun, P; Makarewicz, D; Słomka, M; Wójcik, L; Zalewska, T; Ziemka-Nałecz, M | 1 |
| Erwa, W; Frank, S; Riederer, M; Zechner, R; Zimmermann, R | 1 |
| Chlopicki, S; Klimenko, A; Kuchmerovska, T; Shymanskyy, I | 1 |
| Bian, FN; Dong, LB; Gong, XJ; Guo, M; Jiang, DJ; Jing, LX; Li, D; Li, SF; Li, ZN; Lun, YZ; Luo, N; Sun, CB; Sun, SX; Sun, WP; Xiao, FC; Yu, ZG; Zhang, LB; Zhao, ZG; Zheng, CL; Zhou, SS; Zhou, YM; Zou, W | 1 |
| HUFF, JW | 1 |
| HUFF, JW; PERLZWEIG, WA | 2 |
| LEVITAS, N; ROBINSON, J | 1 |
| DEAL, CC; NAJJAR, VA | 1 |
| Adamus, J; Dołowy, K; Gebicki, J; Nowak, R; Rutkowska, M; Szewczyk, A; Tarasiuk, J; Wrzosek, A; Łukasiak, A | 1 |
| Chlopicki, S; Khodosovskiĭ, MN; Zinchuk, VV | 1 |
| Kazmierczak, P; Przygodzki, T; Sikora, J; Watala, C | 1 |
| Kitamura, S; Miyake, K; Morita, S; Ohta, S; Sanoh, S; Sugihara, K; Tayama, Y | 1 |
| Chung, JH; Hwang, GS; Kang, SM; Lee, H; Oh, J; Park, JC; Ryu, DH; Shin, MJ | 1 |
| Aravindan, S; Austen, BM; Evans, EA; Kadampeswaran, A; Levy, ER; Parsons, RB; Ramsden, DB; Sandhu, KK; Thomas, MG | 1 |
| Mlynarski, W; Polakowska, E; Przygodzki, T; Slominska, E; Watala, C | 1 |
| Gong, XJ; Guo, M; Jing, LX; Li, D; Lun, YZ; Sun, SX; Sun, WP; Xiao, FC; Zhang, LB; Zhou, SS | 1 |
| Grobelski, B; Kazmierczak, P; Przygodzki, T; Watala, C | 1 |
| Fukushima, T; Hayakawa, T; Kakamu, T; Kanda, H; Mori, Y; Sugawara, A; Tsuboi, S; Tsuji, M | 1 |
| Duračková, Z; Liptáková, A; Muchová, J; Országhová, Z; Uličná, O; Watala, C; Zitňanová, I | 1 |
| Kitamura, S; Miyake, K; Ohta, S; Sanoh, S; Sugihara, K; Tayama, Y | 1 |
| Chłopicki, S; Kamiński, K; Kurdziel, M; Sternak, M; Szafarz, M; Szymura-Oleksiak, J; Żołądź, JA | 1 |
| Cao, Y; Guo, M; Li, CY; Li, D; Liu, XX; Sun, CB; Tian, YJ; Yang, TT; Zhou, SS | 1 |
| Cao, Y; Li, D; Li, SZ; Luo, N; Ma, Q; Shi, Q; Zhou, SS | 1 |
| Cao, Y; Gu, XY; Guo, M; Li, D; Lun, YZ; Ma, Q; Sun, WP; Tian, YJ; Wang, XY; Zhou, SS | 1 |
| Asker, D; Parsons, RB; Patel, M; Vasaya, MM | 1 |
| Cravatt, BF; Ulanovskaya, OA; Zuhl, AM | 1 |
| Cao, JM; Cao, Y; Gong, XJ; Guo, J; Guo, M; Li, D; Lun, YZ; Luo, N; Sun, WP; Tian, YJ; Zhou, SS | 1 |
| Milani, ZH; Parsons, RB; Ramsden, DB | 1 |
| Brzezinka, GD; Khurana, K; Kolodziejczyk, AM; Szymonski, M; Targosz-Korecka, M | 1 |
| Fukuwatari, T; Morita, N; Shibata, K; Shibata, Y | 1 |
| Banwat, E; Chetwood, J; Crossey, MM; Dona, AC; Duguru, M; Fye, HK; Garside, DA; Holmes, E; Kasstan, B; Khan, SA; Ladep, NG; Lemoine, M; Lewis, MR; Nicholson, JK; Njai, HF; Njie, R; Okeke, E; Shimakawa, Y; Taal, M; Taylor-Robinson, SD; Thillainayagam, AV; Thursz, MR; Wijeyesekera, A | 1 |
| Fukuwatari, T; Shibata, K; Suzuki, C | 1 |
| Echizen, H; Nobuoka, Y; Ogawa, R | 1 |
| Barrett, SM; Miller, AJ; Pitman, CL; Walden, AG | 1 |
| Auge, D; Fromm, MF; Hoier, E; Maas, R; Mieth, M; Müller, F; Pontones, CA; Renner, B; Zolk, O | 1 |
| Blüher, M; Dietrich, A; Kannt, A; Klöting, N; Pfenninger, A; Schön, MR; Teichert, L; Tönjes, A | 1 |
| Baranska, M; Chlopicki, S; Kaczor, A; Kostogrys, RB; Mateuszuk, L; Pacia, MZ; Rygula, A | 1 |
| da Cunha, DF; Maltos, AL; Monteiro, MC; Moraes, GV; Portari, GV; Vannucchi, H | 1 |
| Baranska, M; Chlopicki, S; Majzner, K | 1 |
| Chlopicki, S; Czarnowska, E; Jakubowski, A; Jasztal, A; Kaminski, K; Sitek, B; Slominska, EM; Smolenski, RT; Sternak, M; Szafarz, M; Walczak, M; Wojcik, T | 1 |
| Chu, J; Dai, G; Fang, Z; Jiang, W; Ju, W; Li, L; Liu, M; Wang, Z; Yang, Q; Yin, X; Zhang, Q; Zhu, B | 1 |
| Chlopicki, S; Kij, A; Przyborowski, K; Sitek, B; Wandzel, K; Wojewoda, M; Zakrzewska, A; Zoladz, JA | 1 |
| Bouma, G; de Vries, EG; Kats-Ugurlu, G; Kema, IP; van Faassen, M; Walenkamp, AM | 1 |
| Araki, H; Araki, S; Chin-Kanasaki, M; Haneda, M; Koya, D; Kume, S; Maegawa, H; Nakagawa, F; Nakazawa, J; Tanaka, Y; Uzu, T | 1 |
| Marwood, RM; Parsons, AE; Parsons, RB; Thomas, MG | 1 |
| Battle, SL; Bielas, JH; Blau, CA; Detraux, D; Devi, A; Ericson, NG; Ferreccio, A; Fiehn, O; Fischer, KA; Gu, H; Hawkins, RD; Hesson, J; Hockenbery, D; Margaretha, L; Margineantu, D; Margolin, AA; Mathieu, J; Moon, RT; Raftery, D; Robitaille, AM; Ruohola-Baker, H; Showalter, M; Sperber, H; Valensisi, C; Wang, Y; Ware, CB; Xu, Z | 1 |
| Baranska, M; Chlopicki, S; Gasior-Glogowska, M; Jasztal, A; Kij, A; Kostogrys, R; Maslak, E; Mateuszuk, L; Sitek, B; Walczak, M; Zakrzewska, A | 1 |
| Blazejczyk, A; Chlopicki, S; Gebicki, J; Marcinek, A; Nasulewicz-Goldeman, A; Nowak, M; Switalska, M; Wietrzyk, J | 1 |
| Chlopicki, S; Fedorowicz, A; Jakubowski, A; Kopec, G; Kutryb-Zając, B; Mateuszuk, Ł; Skórka, T; Słomińska, E; Walczak, M; Zakrzewska, A; Łomnicka, M | 1 |
| Chen, J; Chen, X; Chu, J; Gu, Y; Ju, W; Liu, M; Shen, L; Shi, H; Wang, L; Wang, Z; Yu, P; Zhang, R | 1 |
| Chlopicki, S; Denslow, A; Gebicki, J; Maciejewska, M; Marcinek, A; Nowak, M; Switalska, M; Wietrzyk, J | 1 |
| Garattini, E; Kücükgöze, G; Leimkühler, S; Terao, M | 1 |
| Anand, NN; Birudukota, S; Burri, RR; Dhakshinamoorthy, S; Gosu, R; Hallur, MS; Juluri, S; Kandan, S; Kannt, A; Kristam, R; Langer, T; Parveen, R; Rajagopal, S; Rudolph, C; Ruf, S; Schreuder, H; Shaik, S; Swaminathan, S; Thakur, MK | 1 |
| Ahlqvist, E; Almgren, P; Calbet, JAL; de Pablos-Velasco, P; Edlund, A; Ekman, C; Ekström, O; Eliasson, L; Fernandez, C; Groop, L; Hansson, O; Hjort, L; Holmberg, HC; Jörgensen, SW; Martin-Rincon, M; Mattiasson, M; Morales-Alamo, D; Oskolkov, N; Ottosson, F; Pérez-López, A; Perez-Suarez, I; Stenkula, KG; Ström, K; Vaag, A; Wierup, N; Zhou, Y | 1 |
| Adamus, J; Gebicki, J; Khalpey, Z; Kowalski, R; Slominska, EM; Smolenski, RT; Zabielska, MA | 1 |
| Fattahi, A; Jodati, AR; Latifi, Z; Mihanfar, A; Nejabati, HR; Nouri, M; Pezeshkian, M; Safaie, N; Valiloo, M | 1 |
| Banfield, C; Dowty, M; Holliman, CL; Kay, J; Luo, L; Ramanathan, R; Rodrigues, AD; Zhang, J | 1 |
| Chen, C; Chu, J; Fang, Z; He, A; He, Y; Hua, M; Ju, W; Liu, M; Lu, M; Tao, W; Zhang, S | 1 |
| Amiya, T; Chu, PS; Ebinuma, H; Fukuda, S; Kanai, T; Katayama, T; Mikami, Y; Miyake, R; Nakamoto, N; Shiba, S; Suzuki, T; Taniki, N; Teratani, T; Tsukimi, T; Yamaguchi, A | 1 |
| Goto, H; Ishii, Y; Takeuchi, K; Umehara, K; Yamada, H; Yokouchi, C | 1 |
| Garten, A; Grahnert, A; Hauschildt, S; Müller, G; Petin, K; Sack, U; Weiss, R | 1 |
| Nejabati, HR; Nouri, M; Roshangar, L; Samadi, N | 1 |
| Fu, LL; Hong, H; Hu, M; Mu, RH; Nazmul Islam, M; Tan, YZ; Tang, SS | 1 |
| Chashmniam, S; Dalili, N; Kalantari, S; Nafar, M; Rezaie, D; Samavat, S | 1 |
| Chen, Y; Li, L; Li, P; Liu, C; Zhang, J | 2 |
| Bahrami-Asl, Z; Fattahi, A; Latifi, Z; Mihanfar, A; Nejabati, HR; Nouri, M; Roshangar, L; Samadi, N; Shahnazi, V | 1 |
| Bahrami-Asl, Z; Faridvand, Y; Fathi-Maroufi, N; Nejabati, HR; Nikanfar, S; Nouri, M; Samimifar, D; Schmeisser, K; Shahnazi, V | 1 |
| Feng, B; Mathialagan, S; Rodrigues, AD; Varma, MVS | 1 |
| Gu, JH; Ji, CH; Jiang, B; Liu, Y; Tang, WQ; Zhang, Y; Zhao, J | 1 |
| Fitzpatrick, M; Nguyen, VL; Saldanha, R | 1 |
| Allard, B; Carleton, G; DeBerardinis, RJ; Ellis, AE; Hamilton, PT; Jones, RG; Keyes, S; Kilgour, MK; Liu, EY; Lum, JJ; MacPherson, S; Nelson, BH; Pauly, B; Sheldon, RD; Smazynski, J; Stagg, J; Watson, PH; Williams, KS; Zacharias, LG | 1 |
| Ji, M; Lin, S; Na, N | 1 |
| Gao, Y; Martin, NI; van Haren, MJ | 1 |
| Buijs, N; Campagna, R; Emanuelli, M; Gao, Y; Gutiérrez-de-Terán, H; Innocenti, P; Jespers, W; Martin, NI; Parsons, RB; Sartini, D; van Haren, MJ; van Westen, GJP; Zhang, Y | 1 |
| Biliotti, E; Capuani, G; Esvan, R; Giampaoli, O; Marini, F; Miccheli, A; Palazzo, D; Sciubba, F; Spaziante, M; Taliani, G; Tomassini, A | 1 |
| Chen, X; Deng, W; Fan, C; Gu, J; Guo, T; Jiang, T; Mai, J; Rong, G; Su, Z; Tang, X; Xie, J; Yu, Q; Zhang, J; Zhang, W; Zheng, R | 1 |
| Faridvand, Y; Fathi-Maroufi, N; Ghaffari-Novin, M; Hansson, O; Holmberg, HC; Nejabati, HR; Nikanfar, S; Nouri, M | 1 |
| Nejabati, HR; Roshangar, L | 1 |
| Bamba, T; Izumi, Y; Kawaoka, S; Mizuno, R; Takahashi, M; Yoda, M | 1 |
| Hoser, G; Jeznach, A; Sidor, K; Skirecki, T | 1 |
10 review(s) available for n(1)-methylnicotinamide and niacinamide
| Article | Year |
|---|---|
Transformation and transport: how does metabolic transformation change the affinity of substrates for the renal contraluminal anion and cation transporters?
Topics: Animals; Anions; Biological Transport; Biotransformation; Cations; Humans; Kidney; Kinetics; Niacinamide; p-Aminohippuric Acid | 1990 |
Effects of tryptophan and nicotinamide intakes on in vivo oxidation of tryptophan and excretion of N1-methylnicotinamide in young rats.
Topics: Animals; Dose-Response Relationship, Drug; Niacinamide; Rats; Tryptophan | 1983 |
Newer laboratory methods for assessing nutriture of selected B-complex vitamins.
Topics: Alanine Transaminase; Autoanalysis; Binding, Competitive; Biological Assay; Body Fluids; Child, Preschool; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Erythrocytes; Flavin-Adenine Dinucleotide; Folic Acid; Glutathione Reductase; Humans; Infant; Infant, Newborn; Leukocytes; Methods; Niacin; Niacinamide; Nutritional Physiological Phenomena; Protein Binding; Pyridones; Pyridoxal Phosphate; Pyridoxic Acid; Pyridoxine; Riboflavin; Thiamine; Thiamine Pyrophosphate; Transketolase; Vitamin B Complex; Vitamin B Deficiency | 1984 |
Drug and chemical effects on membrane transport.
Topics: Animals; Anions; Anti-Bacterial Agents; Biological Transport; Cations; Cell Membrane; Citrinin; Energy Metabolism; Glutathione; Kidney; Niacinamide; p-Aminohippuric Acid; Tetraethylammonium; Tetraethylammonium Compounds | 1981 |
[Elucidation of paraquat poisoning mechanism and development of the neuronal death model].
Topics: Animals; Chaperonin 60; Disease Models, Animal; Electron Transport Complex I; Herbicides; Humans; Lipid Peroxidation; Mitochondria; NADH, NADPH Oxidoreductases; Niacinamide; Paraquat; Parkinson Disease; Superoxides | 2002 |
N1-methylnicotinamide (MNAM) as a guardian of cardiovascular system.
Topics: Atherosclerosis; Cardiovascular System; Coronary Artery Disease; Epoprostenol; Humans; Lipid Droplets; Niacinamide; Nitric Oxide | 2018 |
N1-methylnicotinamide as a possible modulator of cardiovascular risk markers in polycystic ovary syndrome.
Topics: Biomarkers; Cardiovascular Diseases; Female; Humans; Niacinamide; Polycystic Ovary Syndrome; Prodromal Symptoms; Risk Factors | 2019 |
N1-Methylnicotinamide: An Anti-Ovarian Aging Hormetin?
Topics: Aging; AMP-Activated Protein Kinases; Animals; Female; Humans; Niacinamide; Polycystic Ovary Syndrome; Reactive Oxygen Species | 2020 |
Nicotinamide N-methyl transferase (NNMT): An emerging therapeutic target.
Topics: Enzyme Inhibitors; Humans; Metabolic Diseases; Neoplasms; Neurodegenerative Diseases; Niacinamide; Nicotinamide N-Methyltransferase; S-Adenosylmethionine | 2021 |
N1-Methylnicotinamide: Is it Time to Consider it as a Dietary Supplement for Athletes?
Topics: Athletes; Cholesterol; Dietary Supplements; Humans; Niacinamide | 2022 |
3 trial(s) available for n(1)-methylnicotinamide and niacinamide
| Article | Year |
|---|---|
Pharmacokinetics of nicotinamide in cancer patients treated with accelerated radiotherapy: the experience of the Co-operative Group of Radiotherapy of the European Organization for Research and Treatment of Cancer.
Topics: Administration, Oral; Area Under Curve; Carbon Dioxide; Carcinoma; Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Dose Fractionation, Radiation; Follow-Up Studies; Half-Life; Head and Neck Neoplasms; Humans; Lung Neoplasms; Nausea; Niacinamide; Oxygen; Pyridones; Radiation-Sensitizing Agents; Tablets; Time Factors; Treatment Outcome; Vomiting | 1998 |
N(1)-methylnicotinamide as an endogenous probe for drug interactions by renal cation transporters: studies on the metformin-trimethoprim interaction.
Topics: Adult; Blood Glucose; Creatinine; Cross-Over Studies; Drug Interactions; Female; HEK293 Cells; Humans; Hypoglycemic Agents; Kidney; Male; Metformin; Niacinamide; Organic Cation Transport Proteins; Trimethoprim; Young Adult | 2015 |
Association of nicotinamide-N-methyltransferase mRNA expression in human adipose tissue and the plasma concentration of its product, 1-methylnicotinamide, with insulin resistance.
Topics: Adult; Aged; Bariatric Surgery; Biomarkers; Case-Control Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Exercise Therapy; Female; Humans; Insulin Resistance; Male; Middle Aged; Niacinamide; Nicotinamide N-Methyltransferase; Obesity; RNA, Messenger; Subcutaneous Fat; Time Factors; Treatment Outcome; Young Adult | 2015 |
213 other study(ies) available for n(1)-methylnicotinamide and niacinamide
| Article | Year |
|---|---|
Direct urinary assay method for N1-methylnicotinamide by soap chromatography.
Topics: Animals; Chromatography, High Pressure Liquid; Niacinamide; Rats; Sodium Dodecyl Sulfate; Spectrophotometry, Ultraviolet | 1979 |
The fate of [14C]streptozotocin in nicotinamide-pretreated mice: observations on pancreatic islet radioactivity and urinary N1-methyl-14C]nicotinamide-excretion.
Topics: Animals; Carbon Radioisotopes; Female; Islets of Langerhans; Methylation; Mice; Niacinamide; Streptozocin; Tissue Distribution | 1979 |
Renal contraluminal transport systems for organic anions (paraaminohippurate, PAH) and organic cations (N1-methyl-nicotinamide, NMeN) do not see the degree of substrate ionization.
Topics: Animals; Biological Transport, Active; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney; Kinetics; Niacinamide; p-Aminohippuric Acid; Rats | 1992 |
The thyroid hormone response element is required for activation of the growth hormone gene promoter by nicotinamide analogs.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Line; Cell Nucleus; Chloramphenicol O-Acetyltransferase; Growth Hormone; NAD; Niacinamide; Promoter Regions, Genetic; Rats; Receptors, Thyroid Hormone; Recombinant Proteins; Transcription, Genetic; Transfection; Triiodothyronine | 1992 |
High-performance liquid chromatographic determination of nicotinamide and its metabolites in human and murine plasma and urine.
Topics: Animals; Chromatography, High Pressure Liquid; Humans; Mice; Niacinamide; Oxides; Pyridines | 1992 |
Estimation of renal tubular secretion in man, in health and disease, using endogenous N-1-methylnicotinamide.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Creatine; Female; Glomerular Filtration Rate; Humans; Kidney Diseases; Kidney Tubules; Male; Middle Aged; Niacinamide | 1992 |
Influence of ADP-ribosyltransferase inhibitors on the intracellular NAD and ATP levels in Ehrlich ascites tumor cells: implication for the altered NAD + ATP-dependent cellular sensitivity to the cytotoxic agents.
Topics: Adenosine Triphosphate; Animals; Azacitidine; Benzamides; Carcinoma, Ehrlich Tumor; Female; Mice; Microsomes; NAD; NAD+ Nucleosidase; Niacinamide; Nicotinamide-Nucleotide Adenylyltransferase; Poly(ADP-ribose) Polymerase Inhibitors; Tumor Cells, Cultured | 1990 |
Tryptophan metabolism in mice infected with Schistosoma mansoni.
Topics: Animals; Cells, Cultured; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; Liver; Male; Mice; Niacinamide; Schistosomiasis mansoni; Serotonin; Tryptophan; Xanthurenates | 1991 |
Interaction of 3'-azido-3'-deoxythymidine with organic ion transport in rat renal basolateral membrane vesicles.
Topics: Animals; Biological Transport; Dose-Response Relationship, Drug; In Vitro Techniques; Kidney Tubules; Male; Niacinamide; p-Aminohippuric Acid; Rats; Rats, Inbred Strains; Tetraethylammonium Compounds; Zidovudine | 1991 |
Transport of organic cations by a renal epithelial cell line (OK).
Topics: Animals; Azides; Biological Transport, Active; Cations; Cell Line; Cell Membrane; Cell-Free System; Epithelium; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney Tubules, Proximal; Niacinamide; Opossums; Piperidines; Temperature; Tetraethylammonium Compounds | 1991 |
Organic cation transport in human renal brush-border membrane vesicles.
Topics: Adult; Biological Transport; Cations; Child; Female; Glucose; Humans; Hydrogen-Ion Concentration; Kidney; Kinetics; Male; Microvilli; Middle Aged; Niacinamide; Regression Analysis; Spectrometry, Fluorescence; Tetraethylammonium; Tetraethylammonium Compounds | 1991 |
N1-methylnicotinamide level in the blood after nicotinamide loading as further evidence for malignant tumor burden.
Topics: Animals; Carbon Tetrachloride Poisoning; Cells, Cultured; DNA Replication; Galactosamine; Inflammation; Liver; Male; Methyltransferases; Mice; Mice, Inbred Strains; Necrosis; Neoplasms, Experimental; Niacinamide; Nicotinamide N-Methyltransferase | 1991 |
The excretion of N1-methyl-2-pyridone-5-carboxylic acid and related compounds in human subjects after oral administration of nicotinic acid, trigonelline and N1-methyl-2-pyridone-5-carboxylic acid.
Topics: Adult; Alkaloids; Female; Humans; Niacin; Niacinamide; Nicotinic Acids | 1991 |
System analysis in multiple dose kinetics: evidence for saturable tubular reabsorption of the organic cation N1-methylnicotinamide in humans.
Topics: Absorption; Adult; Blood Proteins; Cations; Drug Administration Schedule; Female; Humans; Kidney; Kidney Tubules; Niacinamide; Protein Binding; Renal Circulation; Systems Analysis | 1991 |
Rapid and quantitative separation of nicotinamide and its N1-methylated metabolite by Dowex AG50-X4 chromatography.
Topics: Anion Exchange Resins; Chromatography, Liquid; Niacinamide; Resins, Synthetic | 1991 |
Transport of the organic cation N1-methylnicotinamide by the rabbit proximal tubule. II. Reabsorption and secretion in the isolated perfused tubule.
Topics: Absorption; Animals; Biological Transport; Cell Membrane Permeability; Female; Ganglionic Blockers; Kidney Tubules, Proximal; Male; Niacinamide; Piperidines; Rabbits | 1990 |
Transport of organic cations by kidney epithelial cell line LLC-PK1.
Topics: Biological Transport; Cell Line; Epithelium; Kidney; Niacinamide; Piperidines; Tetraethylammonium Compounds | 1990 |
Inhibition kinetics of cationic drugs on N'-methylnicotinamide uptake by brush border membrane vesicles from the dog kidney cortex.
Topics: Animals; Biological Transport, Active; Cations; Dogs; In Vitro Techniques; Kidney Cortex; Kidney Tubules; Kinetics; Microvilli; Niacinamide; Proteins | 1990 |
Transport of the organic cation N1-methylnicotinamide by the rabbit proximal tubule. I. Accumulation in the isolated nonperfused tubule.
Topics: Animals; Chromatography, High Pressure Liquid; Drug Interactions; Female; Kidney Tubules, Proximal; Male; Niacinamide; p-Aminohippuric Acid; Potassium Cyanide; Rabbits | 1990 |
Mechanisms of interactions between organic anions and the organic cation transporter in renal brush border membrane vesicles.
Topics: Animals; Anions; Binding, Competitive; Biological Transport; Cations; Furosemide; Kidney; Kinetics; Microvilli; Molecular Structure; Niacinamide; Probenecid; Rabbits | 1990 |
Effect of endogenous and exogenous polyamines on organic cation transport in rabbit renal plasma membrane vesicles.
Topics: Animals; Biogenic Polyamines; Biological Transport; Cell Membrane; Dose-Response Relationship, Drug; Female; Glucose; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney; Male; Mitoguazone; Niacinamide; Rabbits; Tetraethylammonium Compounds | 1990 |
Estimation of the renal clearance of drugs using endogenous N-1-methylnicotinamide.
Topics: Acute Kidney Injury; Animals; Cephalexin; Cimetidine; Glomerular Filtration Rate; Inulin; Kidney; Kidney Failure, Chronic; Lithium; Male; Niacinamide; Rats; Rats, Inbred Strains | 1990 |
A comparison of N-1-methylnicotinamide clearance with 5 other markers of renal function in models of acute and chronic renal failure.
Topics: Acetylglucosaminidase; Acute Kidney Injury; Animals; Biomarkers; Kidney Failure, Chronic; Kidney Tubular Necrosis, Acute; Kidney Tubules, Proximal; Niacinamide; Rats; Urea | 1990 |
Transport of N1-methylnicotinamide by organic cation-proton exchange in rat liver membrane vesicles.
Topics: Amiloride; Animals; Biological Transport; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cations; Cell Membrane; Imipramine; Kinetics; Liver; Niacinamide; Osmolar Concentration; Protons; Rats; Sodium; Time Factors | 1990 |
Biochemical markers for assessment of niacin status in young men: urinary and blood levels of niacin metabolites.
Topics: Adult; Biomarkers; Humans; Kinetics; Male; Niacin; Niacinamide; Nutritional Status | 1989 |
Effect of light on reactions between N1-methylnicotinamide and methyl ketones.
Topics: Acetone; Butanones; Humans; Light; Niacinamide; Spectrometry, Fluorescence | 1989 |
Gentamicin and verapamil compete for a common transport mechanism in renal brush border membrane vesicles.
Topics: Animals; Biological Transport; Dogs; Gentamicins; In Vitro Techniques; Kidney; Microvilli; Niacinamide; p-Aminohippuric Acid; Verapamil | 1989 |
Detection of 5-methylcytosine removal from DNA of Friend erythroleukemia cells following exposure to several differentiating agents.
Topics: 5-Methylcytosine; Acetamides; Animals; Cell Differentiation; Cytosine; Dimethyl Sulfoxide; DNA; Friend murine leukemia virus; Leukemia, Erythroblastic, Acute; Niacinamide; Tumor Cells, Cultured | 1989 |
Electron transfer process in cytochrome oxidase after pulse radiolysis.
Topics: Animals; Cattle; Copper; Electron Transport; Electron Transport Complex IV; Free Radicals; Heme; Hydrogen-Ion Concentration; Kinetics; Myocardium; Niacinamide; Oxidation-Reduction; Pulse Radiolysis; Spectrophotometry; Spectrum Analysis; Thermodynamics | 1989 |
N,N'-dicyclohexylcarbodiimide inactivates organic cation transport in renal brush border membranes.
Topics: Animals; Biological Transport; Carbodiimides; Dicyclohexylcarbodiimide; Dogs; Dose-Response Relationship, Drug; Ethyldimethylaminopropyl Carbodiimide; In Vitro Techniques; Kidney; Microvilli; Niacinamide; Protons; Quinolines; Sodium | 1987 |
Influence of ethanol upon the introduction of tyrosine aminotransferase in liver, upon the NAD content in liver and brain, and upon the activity of glutamate oxalate aminotransferase and glutamate pyruvate aminotransferase in the serum of rats.
Topics: Adrenalectomy; Alanine Transaminase; Animals; Aspartate Aminotransferases; Brain Chemistry; Ethanol; Liver; Methionine; NAD; Niacinamide; Rats; Rats, Inbred Strains; Tryptophan; Tyrosine Transaminase | 1985 |
Urinary excretion of 3-methyladenine and 1-methylnicotinamide by rats, following administration of [methyl-14C]methyl methanesulphonate and comparison with administration of [14C]methionine or formate.
Topics: Adenine; Alkylation; Animals; Chromatography, Ion Exchange; Female; Formates; Methionine; Methyl Methanesulfonate; Methylation; Niacinamide; Rats | 1985 |
N1-methylnicotinamide transport by isolated perfused snake proximal renal tubules.
Topics: Animals; Biological Transport; Body Water; Epithelium; In Vitro Techniques; Kidney Tubules, Proximal; Kinetics; Niacinamide; Osmolar Concentration; Perfusion; Piperidines; Snakes; Sodium; Tetraethylammonium; Tetraethylammonium Compounds | 1986 |
Chromate reduction by rabbit liver aldehyde oxidase.
Topics: Aldehyde Oxidase; Aldehyde Oxidoreductases; Allopurinol; Animals; Chromates; Cytosol; In Vitro Techniques; Kinetics; Liver; Niacinamide; Oxidation-Reduction; Potassium Cyanide; Rabbits; Vitamin K | 1986 |
Transport of organic cations in brush border membrane vesicles from rabbit kidney cortex.
Topics: Animals; Biological Transport; Female; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney Cortex; Kinetics; Male; Microvilli; Morphine; Niacinamide; Potassium; Rabbits; Tetraethylammonium; Tetraethylammonium Compounds; Valinomycin | 1986 |
Leucine excess and niacin status in rats.
Topics: Animals; Body Weight; Diet; Edible Grain; India; Leucine; Liver; Male; Niacin; Niacinamide; Nicotinamide Mononucleotide; Nutritional Status; Pellagra; Rats; Rats, Inbred Strains; Statistics as Topic; Tryptophan; Vitamin B 6 Deficiency | 1987 |
Essential tyrosine residues in transport of organic cations in renal BBMV.
Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Basement Membrane; Biological Transport, Active; Imidazoles; Kidney Cortex; Male; Niacinamide; Rabbits; Tyrosine | 1987 |
The neurotoxins 1-methyl-4-phenylpyridinium and 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine are substrates for the organic cation transporter in renal brush border membrane vesicles.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Biological Transport; Cations; Dogs; Kidney Cortex; Microvilli; Neurotoxins; Niacinamide; p-Aminohippuric Acid; Pyridines; Pyridinium Compounds; Structure-Activity Relationship; Valinomycin | 1987 |
Organic cation secretion in flounder renal tissue.
Topics: 2,4-Dinitrophenol; Animals; Biological Transport, Active; Cations; Dinitrophenols; Flatfishes; Flounder; Glomerular Filtration Rate; Kidney; Mercuric Chloride; Niacinamide; Ouabain; Reference Values; Sodium Cyanide; Tetraethylammonium Compounds | 1987 |
Interactions of organic anions with the organic cation transporter in renal BBMV.
Topics: Animals; Biological Transport, Active; Furosemide; Hydrogen-Ion Concentration; Kidney; Kidney Tubules, Proximal; Kinetics; Microvilli; Niacinamide; Probenecid; Rabbits | 1988 |
Oxidation in H2O and D2O of 6-ethyl-5H-dibenz(c,e)azepine and 1-methylnicotinamide by aldehyde oxidase from rabbit liver.
Topics: Aldehyde Oxidase; Aldehyde Oxidoreductases; Animals; Deuterium; Deuterium Oxide; Dibenzazepines; Hydrogen-Ion Concentration; Kinetics; Liver; Niacinamide; Oxidation-Reduction; Rabbits; Water | 1985 |
Formation of the N'-methylnicotinamide adenine dinucleotide derivative of NAD in intact rat pituitary tumor GH3 and human promyelocytic leukemia HL-60 cells.
Topics: Adenosine Triphosphate; Animals; Cell Line; Guanosine Triphosphate; Humans; Leukemia, Myeloid, Acute; NAD; NAD+ Nucleosidase; Niacinamide; Nucleotidyltransferases; Pituitary Neoplasms; Poly(ADP-ribose) Polymerases; Rats; Substrate Specificity; Time Factors | 1986 |
Estimation of renal blood flow by use of endogenous N1-methylnicotinamide in rats.
Topics: Acute Kidney Injury; Animals; Kidney; Male; Metabolic Clearance Rate; Niacinamide; p-Aminohippuric Acid; Rats; Rats, Inbred Strains; Renal Circulation | 1985 |
Electroneutral transport of organic cations in canine renal brush border membrane vesicles (BBMV).
Topics: Animals; Biological Transport; Cations; Diffusion; Dogs; In Vitro Techniques; Kidney; Microvilli; Niacinamide; Potassium; Sodium; Tritium | 1985 |
Influence of chlorpromazine, reserpine and lithium carbonate upon the induction of the tyrosine aminotransferase (TAT) in the rat liver.
Topics: Adrenalectomy; Animals; Chlorpromazine; Enzyme Induction; Female; Lithium; Lithium Carbonate; Liver; Methionine; Niacinamide; Prednisolone; Rats; Rats, Inbred Strains; Reserpine; Tryptophan; Tyrosine Transaminase | 1983 |
The differences in growth and activity of the tryptophan-NAD pathway between Wistar and Sprague Dawley strains of rats fed on tryptophan-limited diet.
Topics: Animals; Carboxy-Lyases; Growth; Indoleamine-Pyrrole 2,3,-Dioxygenase; Male; NAD; Niacin; Niacinamide; Nicotinic Acids; Quinolinic Acids; Rats; Rats, Inbred Strains; Species Specificity; Tryptophan; Tryptophan Oxygenase | 1982 |
Prediction of renal tubular secretion of tetraethylammonium bromide by use of endogenous N1-methylnicotinamide in the rat.
Topics: Animals; Kidney Tubules; Male; Metabolic Clearance Rate; Niacinamide; Rats; Rats, Inbred Strains; Tetraethylammonium Compounds | 1982 |
The bioavailability for humans of bound niacin from wheat bran.
Topics: Adult; Humans; Male; Middle Aged; Niacin; Niacinamide; Nutritive Value; Triticum | 1982 |
Quantitation of urinary niacin metabolites by reversed-phase liquid chromatography.
Topics: Adult; Chromatography, High Pressure Liquid; Humans; Male; Niacin; Niacinamide | 1982 |
Renal transport of 2'-deoxytubercidin in mice.
Topics: Animals; Azides; Biological Transport; Choline; Deoxyadenosines; Hydrogen-Ion Concentration; Inulin; Kidney; Male; Mice; Mice, Inbred AKR; Niacinamide; p-Aminohippuric Acid; Quaternary Ammonium Compounds; Ribonucleosides; Sodium Azide; Tissue Distribution; Tubercidin | 1982 |
Determination of niacin metabolites 1-methyl-5-carboxylamide-2-pyridone and N-1-methylnicotinamide in urine by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Humans; Niacin; Niacinamide; Reference Standards | 1982 |
Metabolic effects of nicotinamide administration in rats.
Topics: Animals; Blood Glucose; Choline; Creatinine; Cystathionine gamma-Lyase; Lipid Metabolism; Liver; Male; Methyltransferases; Niacinamide; Nicotinamide N-Methyltransferase; Rats; Rats, Inbred Strains | 1983 |
Characteristics of nicotinamide and N1-methylnicotinamide protection from alloxan diabetes in mice.
Topics: Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; NAD; Niacinamide | 1983 |
Effects of chronic ethanol feeding on the metabolism of tryptophan and nicotinamide in rats.
Topics: Animals; Diet; Ethanol; Male; Niacin; Niacinamide; Oxidation-Reduction; Rats; Rats, Inbred Strains; Tryptophan | 1983 |
[Effect of L-tryptophan, nicotinamide, L-methionine and 1-methylnicotinamide on the embryotoxic effect of various substances].
Topics: 6-Aminonicotinamide; Animals; Cyclophosphamide; Drug Interactions; Embryo, Mammalian; Female; Hydroxyurea; Mercaptopurine; Methionine; Mice; Niacinamide; Pregnancy; Tryptophan | 1983 |
Effect of experimental acute renal failure on intrinsic renal tubular secretory clearance of organic cations in rats.
Topics: Acute Kidney Injury; Animals; Cations; Kidney Glomerulus; Kidney Tubules; Niacinamide; Rats; Tetraethylammonium; Tetraethylammonium Compounds | 1983 |
Inhibition of tryptophan metabolism by oestrogens in the rat: a factor in the aetiology of pellagra.
Topics: Animals; Castration; Estrone; Female; Liver; NAD; NADP; Niacinamide; Pellagra; Rats; Rats, Inbred Strains; Tryptophan | 1984 |
N-methylnicotinamide as a possible prognostic indicator of recovery from leukaemia in patients treated with total-body irradiation and bone marrow transplants.
Topics: Adult; Bone Marrow Transplantation; Female; Humans; Leukemia, Myeloid, Acute; Male; Niacinamide; Prognosis; Whole-Body Irradiation | 1984 |
Tetraethylammonium transport by isolated perfused snake renal tubules.
Topics: Animals; Biological Transport; Cold Temperature; Cyanides; Kidney Tubules; Kinetics; Mathematics; Niacinamide; Perfusion; Snakes; Sodium; Tetraethylammonium Compounds | 1984 |
Estimation of renal secretory function for organic cations by endogenous N1-methylnicotinamide in rats with experimental renal failure.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Cations; Glomerular Filtration Rate; Kidney; Kidney Function Tests; Male; Metabolic Clearance Rate; Niacinamide; Rats; Rats, Inbred Strains; Tetraethylammonium; Tetraethylammonium Compounds | 1984 |
Nicotinamide methylation and its relation to NAD synthesis in rat liver tissue culture. Biochemical basis for the physiological activities of 1-methylnicotinamide.
Topics: Adenosine Triphosphate; Animals; Carbon Radioisotopes; Cells, Cultured; Cytosol; Female; In Vitro Techniques; Kinetics; Liver; Methylation; NAD; Niacinamide; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1984 |
Nicotinamide and other inhibitors of ADP-ribosylation block deoxyglucose uptake in cultured cells.
Topics: Adenosine Diphosphate Ribose; Adipose Tissue; Animals; Antibodies; Bone and Bones; Cell Line; Deoxy Sugars; Deoxyglucose; Insulin; Kidney; Mice; Niacin; Niacinamide; Nucleoside Diphosphate Sugars; Pyridoxine; Receptor, Insulin | 1984 |
Effects of nicotinamide and structural analogs on DNA synthesis and cellular replication of rat hepatoma cells.
Topics: Animals; Benzamides; Cell Division; Cells, Cultured; DNA, Neoplasm; Liver Neoplasms, Experimental; Methyl Methanesulfonate; Niacinamide; Rats; Rats, Inbred BUF | 1984 |
Prevention by nicotinamide of desensitization to thyrotropin stimulation in cultured human thyroid cells.
Topics: Cells, Cultured; Cyclic AMP; Cycloheximide; Drug Synergism; Graves Disease; Humans; Kinetics; Niacinamide; Structure-Activity Relationship; Thyroid Gland; Thyrotropin-Releasing Hormone | 1981 |
NAD glycohydrolase activity in the liver of rats fed on excess leucine diet and low or high protein diet.
Topics: Animals; Body Weight; Dietary Proteins; Dose-Response Relationship, Drug; Leucine; Liver; Male; NAD; NAD+ Nucleosidase; Niacin; Niacinamide; Nicotinic Acids; Rats; Rats, Inbred Strains | 1982 |
Influence of D-galactosamine upon the NAD-metabolism in rat liver.
Topics: Adrenalectomy; Animals; Chemical and Drug Induced Liver Injury; Galactosamine; Liver; Methionine; NAD; Niacinamide; Nucleotidyltransferases; Poly(ADP-ribose) Polymerases; Rats; Rats, Inbred Strains; Tryptophan | 1983 |
Energetics of the one-electron steps in the NAD+/NADH redox couple.
Topics: Electrons; Kinetics; NAD; Niacinamide; Oxidation-Reduction; Potentiometry | 1980 |
Fluorometric quantitation of picomole amounts of 1-methylnicotinamide and nicotinamide in serum.
Topics: Animals; Humans; Microchemistry; NAD; NADP; Niacinamide; Rats; Spectrometry, Fluorescence | 1980 |
Urinary excretion of methylated purines and 1-methyl-nicotinamide following administration of methylating carcinogens.
Topics: 1,2-Dimethylhydrazine; Adenine; Alkylating Agents; Animals; Carcinogens; Dimethylhydrazines; Dimethylnitrosamine; Guanine; Male; Methyl Methanesulfonate; Methylation; Methylnitronitrosoguanidine; Niacinamide; Rats | 1980 |
The pH dependence of xanthine oxidase catalysis in basic solution.
Topics: Deuterium; Hydrogen-Ion Concentration; Kinetics; Niacinamide; Nicotinic Acids; Pyridinium Compounds; Quinolinium Compounds; Xanthine Oxidase | 1980 |
An X-ray study on the interaction between indole ring and pyridine coenzymes: crystal structure of 1-methyl-3-carbamoylpyridinium: indole-3-acetic acid (1:1) monohydrate charge-transfer complex.
Topics: Chemical Phenomena; Chemistry; Coenzymes; Hydrogen Bonding; Indoleacetic Acids; Indoles; Models, Molecular; Molecular Conformation; Niacinamide; Pyridines; X-Ray Diffraction | 1980 |
Mechanisms of organic cation transport in kidney plasma membrane vesicles: 1. Countertransport studies.
Topics: Animals; Biological Transport; Biological Transport, Active; Cations; Cell Membrane; Choline; Dogs; Kidney Cortex; Niacinamide | 1980 |
Metabolism of NAD and N1-methylnicotinamide in growing and growth-arrested cells.
Topics: Animals; Blood; Cell Division; Cells, Cultured; Culture Media; Kidney; Kinetics; NAD; Niacinamide; Rats | 1980 |
N'-Methylnicotinamide in human urine.
Topics: Adolescent; Adult; Aged; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Niacinamide | 1981 |
Measurement of niacin metabolites in urine by high pressure liquid chromatography. A simple, sensitive assay of niacin nutritional status.
Topics: Alkaloids; Animals; Chromatography, High Pressure Liquid; Isonicotinic Acids; Male; Niacinamide; Nicotinic Acids; Pyridones; Rats; Rats, Inbred Strains | 1981 |
1-methylnicotinamide and NAD metabolism in normal and transformed normal rat kidney cells.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Kidney; NAD; Niacinamide; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1981 |
Luminal transport system for H+/organic cations in the rat proximal tubule. Kinetics, dependence on pH; specificity as compared with the contraluminal organic cation-transport system.
Topics: Animals; Biological Transport, Active; Cations; Cimetidine; Histamine H2 Antagonists; Hydrogen; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney Tubules, Proximal; Kinetics; Male; Niacinamide; Perfusion; Pyridinium Compounds; Rats; Rats, Wistar; Tetraethylammonium Compounds | 1995 |
Characterization of cimetidine transport in LLCPK1 cells.
Topics: Amiloride; Animals; Anti-Bacterial Agents; Azides; Biological Transport; Carrier Proteins; Cell Line; Cimetidine; Guanidine; Guanidines; Kidney; Macrolides; Microscopy, Fluorescence; Models, Biological; Niacinamide; Proton-Translocating ATPases; Quinidine; Quinine; Sodium Azide; Sodium-Hydrogen Exchangers; Swine; Tetraethylammonium; Tetraethylammonium Compounds | 1994 |
Electron transfer process in milk xanthine dehydrogenase as studied by pulse radiolysis.
Topics: Animals; Electron Transport; Free Radicals; Kinetics; Milk; Niacinamide; Oxidation-Reduction; Pulse Radiolysis; Salicylates; Xanthine Dehydrogenase | 1993 |
Altered clearance of N-1 methylnicotinamide associated with the use of low doses of cyclosporine.
Topics: Analysis of Variance; Cyclosporine; Drug Therapy, Combination; Humans; Kidney Function Tests; Kidney Tubules, Proximal; Metabolic Clearance Rate; Niacinamide; Nifedipine; Renal Circulation | 1994 |
Bisubstrates: substances that interact with renal contraluminal organic anion and organic cation transport systems. I. Amines, piperidines, piperazines, azepines, pyridines, quinolines, imidazoles, thiazoles, guanidines and hydrazines.
Topics: Animals; Anions; Biological Transport, Active; Buffers; Cations; Cell Membrane Permeability; Chemical Phenomena; Chemistry, Physical; Kidney; Male; Niacinamide; p-Aminohippuric Acid; Rats; Rats, Wistar | 1993 |
Bisubstrates: substances that interact with both, renal contraluminal organic anion and organic cation transport systems. II. Zwitterionic substrates: dipeptides, cephalosporins, quinolone-carboxylate gyrase inhibitors and phosphamide thiazine carboxylate
Topics: Animals; Anions; Biological Transport, Active; Buffers; Cations; Cell Membrane Permeability; Chemical Phenomena; Chemistry, Physical; Kidney; Male; Niacinamide; p-Aminohippuric Acid; Rats; Rats, Wistar | 1993 |
Radical formation site of cerebral complex I and Parkinson's disease.
Topics: Animals; Brain; Cattle; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Hydroxyl Radical; Lipid Peroxidation; Mitochondria; NAD; NAD(P)H Dehydrogenase (Quinone); Niacinamide; Paraquat; Parkinson Disease; Reactive Oxygen Species; Superoxide Dismutase; Superoxides | 1995 |
Elevation of cerebrospinal fluid choline levels by nicotinamide involves the enzymatic formation of N1-methylnicotinamide in brain tissue.
Topics: Acetylcholine; Animals; Brain; Choline; Chromatography, High Pressure Liquid; Male; Niacinamide; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Spectrophotometry, Ultraviolet; Tritium | 1996 |
Nicotinamide derivatives and mitochondrial respiration.
Topics: Animals; Female; Kinetics; Mitochondria, Liver; Niacinamide; Oxygen Consumption; Rats; Rats, Wistar | 1996 |
Characterization of guanidine transport in human renal brush border membranes.
Topics: Biological Transport; Guanidine; Guanidines; Humans; Kidney; Membrane Potentials; Microvilli; Niacinamide; Protons; Tetraethylammonium; Tetraethylammonium Compounds | 1997 |
Increased conversion ratio of tryptophan to niacin in severe food restriction.
Topics: Animals; Food Deprivation; Kynurenic Acid; Male; Niacin; Niacinamide; Rats; Rats, Wistar; Tryptophan; Xanthurenates | 1998 |
rOCT2 is a basolateral potential-driven carrier, not an organic cation/proton exchanger.
Topics: Animals; Biological Transport; Carrier Proteins; Cell Membrane; Cells, Cultured; Cyclosporine; Dogs; Female; Gene Library; In Vitro Techniques; Kinetics; Membrane Potentials; Niacinamide; Oocytes; Organic Cation Transport Proteins; Organic Cation Transporter 2; Probenecid; Quinacrine; Quinine; Rats; Recombinant Proteins; Tetraethylammonium; Xenopus laevis | 1999 |
Renal clearance of N(1)-methylnicotinamide: a sensitive marker of the severity of liver dysfunction in cirrhosis.
Topics: Adult; Biological Transport, Active; Biomarkers; Case-Control Studies; Creatinine; Humans; Inulin; Kidney; Liver Cirrhosis; Male; Metabolic Clearance Rate; Middle Aged; Niacinamide | 2000 |
Determination of N1-methylnicotinamide by HPLC postcolumn photoirradiation.
Topics: Chromatography, High Pressure Liquid; Crown Ethers; Ethers, Cyclic; Humans; Hydrogen Peroxide; Indicators and Reagents; Niacinamide; Ultraviolet Rays | 1999 |
Reductions of nitro and 9-Oxo groups of environmental nitrofluorenes by the rat mammary gland in vitro.
Topics: Air Pollutants; Allopurinol; Animals; Breast; Cytosol; Dicumarol; Female; Fluorenes; Hypoxanthine; Indomethacin; Microsomes; Niacinamide; Oxidation-Reduction; Oxygen; Pyrazoles; Pyrimidines; Rats; Rats, Sprague-Dawley; Rutin; Vitamin K; Xanthine | 2000 |
Validation of an HPLC method for the determination of urinary and plasma levels of N1-methylnicotinamide, an endogenous marker of renal cationic transport and plasma flow.
Topics: Biomarkers; Calibration; Cations; Chromatography, High Pressure Liquid; Humans; Ion Transport; Kidney; Niacinamide; Reference Standards; Sensitivity and Specificity; Spectrometry, Fluorescence | 2001 |
Rapid calmodulin-dependent interdomain electron transfer in neuronal nitric-oxide synthase measured by pulse radiolysis.
Topics: Calmodulin; Electron Transport; Free Radicals; Mutation; Niacinamide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Peptide Fragments; Protein Structure, Tertiary; Pulse Radiolysis | 2001 |
Possible role of 1-methylnicotinamide in the pathogenesis of Parkinson's disease.
Topics: Animals; Brain; Cell Fractionation; Cytosol; Dopamine; Dose-Response Relationship, Drug; Gas Chromatography-Mass Spectrometry; Hydrogen-Ion Concentration; Injections; Lipid Peroxidation; Liver; Male; Methyltransferases; NADH Dehydrogenase; Niacinamide; Nicotinamide N-Methyltransferase; Parkinson Disease; Rats; Rats, Wistar; Substantia Nigra | 2002 |
Folic acid, leucovorin, vitamin B12, and the excretion of N1-methylnicotinamide.
Topics: Folic Acid; Humans; Leucovorin; Niacin; Niacinamide; Vitamin B 12; Vitamin B Complex | 1952 |
Excretion of N1-methylnicotinamide and the 6-pyridone of N1-methylnicotinamide in urine of human subjects.
Topics: Benzimidazoles; Niacin; Niacinamide; Nicotinic Acids; Pyridones; Urine | 1953 |
[Liver function test in pregnancy; effect of trigonellamide (N1-methylnicotinamide chloride) on pyruvic, lactic, and amino acids in the blood in liver insufficiency in pregnancy].
Topics: Amino Acids; Chlorides; Hepatic Insufficiency; Liver Function Tests; Niacin; Niacinamide; Nicotinic Acids; Pregnancy | 1953 |
Preparation of 2- and 6-pyridones of N1-methylnicotinamide.
Topics: Benzimidazoles; Niacin; Niacinamide; Nicotinic Acids; Oxidation-Reduction; Pyridones | 1954 |
On the fluorometric determination of N1-methylnicotinamide.
Topics: Fluorometry; Niacin; Niacinamide; Nicotinic Acids | 1954 |
On the structure of reduced N1-methylnicotinamide.
Topics: Niacin; Niacinamide; Nicotinic Acids | 1954 |
Mammalian conversion of C14 carboxyl-labeled 3-hydroxyanthranilic acid into N1-methylnicotinamide.
Topics: 3-Hydroxyanthranilic Acid; Aminobenzoates; Niacin; Niacinamide; Nicotinic Acids | 1954 |
A simple method for the determination of N1-methylnicotinamide in urine.
Topics: Body Fluids; Niacin; Niacinamide; Nicotinic Acids | 1957 |
[Modifications in the urinary excretion of N1-methylnicotinamide in patients after various types of surgical interventions].
Topics: Niacin; Niacinamide; Nicotinic Acids; Surgical Procedures, Operative | 1958 |
Some aspects of tryptophan metabolism in human subjects. I. Nitrogen balances, blood pyridine nucleotides and urinary excretion of N1-methylnicotinamide and N1-methyl-2-pyridone-5-carboxamide on a low-niacin diet.
Topics: Diet; Humans; Niacin; Niacinamide; Nitrogen; Nucleosides; Nucleotides; Pyridones; Tryptophan; Vitamins | 1958 |
Inhibition of the renal tubular transport of N1-methylnicotinamide (NMN) by 1,1-dialkylpiperidinium compounds in the avian kidney.
Topics: Kidney; Niacin; Niacinamide; Nicotinic Acids; Piperidines | 1959 |
Studies of the renal tubular transport characteristics of N1-methylnicotinamide and tetraalkylammonium compounds in the avian kidney.
Topics: Ammonium Compounds; Kidney; Niacin; Niacinamide; Nicotinic Acids; Quaternary Ammonium Compounds | 1959 |
Preparation of N1-methylnicotinamide chloride by Dowex-2 chloride.
Topics: Ion Exchange Resins; Niacin; Niacinamide; Nicotinic Acids; Resins, Synthetic | 1962 |
Studies on the renal tubular secretion of N1-methylnicotinamide.
Topics: Biological Transport; Kidney; Niacin; Niacinamide; Nicotinic Acids; Potassium | 1961 |
[On the fluorimetric determination of thiamine, riboflavin, 4-pyridoxic acid and N1-methylnicotinamide in urine].
Topics: Fluorometry; Humans; Niacin; Niacinamide; Nicotinic Acids; Pyridoxic Acid; Riboflavin; Thiamine; Vitamin B 6 | 1962 |
[Urinary elimination of N1-methylnicotinamide and NI-methyl-2-pyridone-5-carboxamide in man].
Topics: Humans; Male; Niacin; Niacinamide; Pyridones | 1961 |
REACTIONS OF N1-METHYLNICOTINAMIDE CATION AND ANALOGUES WITH DILUTE ALKALI.
Topics: Alkalies; Cations; Chemical Phenomena; Chemistry; Hydroxides; Iodides; Niacin; Niacinamide; Nicotinic Acids; Perchlorates; Pyridines; Research; Spectrum Analysis | 1964 |
USE OF ION-EXCHANGE RESINS FOR THE DETERMINATION OF N1-METHYLNICOTINAMIDE IN HUMAN URINE.
Topics: Chromatography; Equipment and Supplies; Fluorescence; Fluorometry; Humans; Ion Exchange Resins; Niacinamide; Research; Urine | 1965 |
The catalytic formation of the fluorescent condensation product of N1-methylnicotinamide and alkaline acetone.
Topics: Acetone; Catalysis; Fluorescence; Niacin; Niacinamide; Nicotinic Acids | 1955 |
Analytical study of blood and urine for free pantothenic acid and N1-methylnicotinamide in man.
Topics: Blood; Body Fluids; Niacin; Niacinamide; Nicotinic Acids; Pantothenic Acid; Urine | 1955 |
The use of casual urine specimens in the evalation of the excretion rates of thiamine, riboflavin and N1-methylnicotinamide.
Topics: Humans; Niacin; Niacinamide; Nicotinic Acids; Riboflavin; Thiamine; Vitamin B 12; Vitamin B Complex | 1959 |
The significance of dietary pyridoxine, niacin and protein in the conversion of tryptophan to N1-methylnicotinamide.
Topics: Diet; Humans; Niacin; Niacinamide; Nicotinic Acids; Pyridoxine; Tryptophan | 1950 |
Conversion of monomethyl-l-tryptophan to niacin and N1-methylnicotinamide by the rat.
Topics: Animals; Niacin; Niacinamide; Nicotinic Acids; Rats; Tryptophan | 1950 |
The excretion of N1-methylnicotinamide and creatinine as influenced by vitamin B12 and various methyl donors.
Topics: Creatinine; Methionine; Niacin; Niacinamide; Vitamin B 12 | 1952 |
Renal tubular elimination of N1-methylnicotinamide.
Topics: Humans; Kidney; Niacinamide | 1950 |
The fluorimetric estimation of N1-methylnicotinamide and its differentiation from coenzyme.
Topics: Coenzymes; Enzymes; Niacin; Niacinamide | 1950 |
Quantitation of the niacin metabolites 1-methylnicotinamide and l-methyl-2-pyridone-5-carboxamide in random spot urine samples, by ion-pairing reverse-phase HPLC with UV detection, and the implications for the use of spot urine samples in the assessment o
Topics: Chromatography, High Pressure Liquid; Niacin; Niacinamide; Pyridones; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 2005 |
Topical application of 1-methylnicotinamide in the treatment of rosacea: a pilot study.
Topics: Administration, Topical; Adult; Chronic Disease; Dermatologic Agents; Facial Dermatoses; Female; Gels; Humans; Male; Middle Aged; Niacinamide; Pilot Projects; Rosacea | 2005 |
Estimation of aldehyde oxidase activity in vivo from conversion ratio of N1-methylnicotinamide to pyridones, and intraspecies variation of the enzyme activity in rats.
Topics: Aldehyde Oxidase; Animals; Liver; Male; Niacinamide; Rats; Rats, Inbred Strains; Species Specificity | 2006 |
Spectrofluorimetric determination of drugs containing active methylene group using N1-methyl nicotinamide chloride as a fluorigenic agent.
Topics: Acebutolol; Fluorescent Dyes; Methane; Niacinamide; Pentoxifylline; Pharmaceutical Preparations; Propafenone; Spectrometry, Fluorescence | 2006 |
Developmental changes of aldehyde oxidase in postnatal rat liver.
Topics: Age Factors; Aldehyde Oxidase; Animals; Benzaldehydes; Blotting, Western; Cytosol; Hydroxylation; Liver; Methotrexate; Niacinamide; Oxidation-Reduction; Rats; Rats, Sprague-Dawley | 2007 |
1-Methylnicotinamide (MNA), a primary metabolite of nicotinamide, exerts anti-thrombotic activity mediated by a cyclooxygenase-2/prostacyclin pathway.
Topics: Animals; Aorta; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Epoprostenol; Fibrinolytic Agents; Hypertension; In Vitro Techniques; Lactones; Male; Mesenteric Arteries; Niacinamide; Platelet Aggregation; Prostaglandins; Rats; Rats, Wistar; Sulfones; Vasodilation; Venous Thrombosis | 2007 |
Whole blood NAD and NADP concentrations are not depressed in subjects with clinical pellagra.
Topics: Adolescent; Adult; Female; Humans; Male; Middle Aged; NAD; NADP; Niacinamide; Pellagra; Pyridones; Sensitivity and Specificity; Time Factors | 2007 |
1-Methylnicotinamide stimulates cell growth and inhibits hemoglobin synthesis in differentiating murine erythroleukemia cells.
Topics: Animals; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Erythropoiesis; Globins; Hemoglobins; Leukemia, Erythroblastic, Acute; Mice; Niacinamide; RNA, Messenger; Time Factors | 2007 |
Anti-inflammatory effect of 1-methylnicotinamide in contact hypersensitivity to oxazolone in mice; involvement of prostacyclin.
Topics: Adoptive Transfer; Animals; Anti-Inflammatory Agents; Benzofurans; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Dermatitis, Contact; Dermatologic Agents; Disease Models, Animal; Endothelium, Vascular; Epoprostenol; Integrin alpha4; Intercellular Adhesion Molecule-1; Male; Mice; Niacinamide; Oxazolone; Propionates; Receptors, Epoprostenol; Receptors, Prostaglandin; Skin | 2008 |
A fluorometric method for the determination of the 6-pyridone of N1-methylnicotinamide in urine.
Topics: Benzimidazoles; Humans; Niacinamide; Pyridones | 1949 |
Aldehyde oxidase-catalyzed metabolism of N1-methylnicotinamide in vivo and in vitro in chimeric mice with humanized liver.
Topics: Aldehyde Oxidase; Animals; Catalysis; Chimera; Chromatography, High Pressure Liquid; Humans; Liver; Mice; Mice, SCID; Niacinamide | 2008 |
Metabolites of the radiosensitizer nicotinamide are unlikely to contribute to the degree of emesis observed with the parent drug.
Topics: Animals; Arteries; Ileum; Isotonic Solutions; Male; Niacinamide; Peristalsis; Radiation-Sensitizing Agents; Rats; Rats, Wistar; Tail; Vasoconstriction; Vomiting | 2007 |
Neuroprotective effects of nicotinamide and 1-methylnicotinamide in acute excitotoxicity in vitro.
Topics: Animals; Calcium; Cells, Cultured; Excitatory Amino Acid Agonists; Glutamic Acid; In Vitro Techniques; Membrane Potential, Mitochondrial; N-Methylaspartate; Neurons; Neuroprotective Agents; Niacinamide; Oxidative Stress; Rats | 2008 |
Therapeutic potential of 1-methylnicotinamide against acute gastric lesions induced by stress: role of endogenous prostacyclin and sensory nerves.
Topics: Acute Disease; Animals; Epoprostenol; Gastric Acid; Gastric Mucosa; Male; Neurons, Afferent; Niacinamide; Rats; Rats, Wistar; Stomach Ulcer; Stress, Physiological | 2008 |
Nicotinamide and 1-methylnicotinamide reduce homocysteine neurotoxicity in primary cultures of rat cerebellar granule cells.
Topics: Analysis of Variance; Animals; Animals, Newborn; Cell Count; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Drug Interactions; Homocysteine; Neurons; Neuroprotective Agents; Neurotoxins; Niacinamide; Rats | 2008 |
The location of the reactive carbon in N1-methylnicotinamide.
Topics: Carbon; Niacinamide | 1948 |
An investigation of transmethylation from N1-methylnicotinamide.
Topics: Niacinamide | 1948 |
Matrix metaloproteinases activity during the evolution of hypoxic-ischemic brain damage in the immature rat. The effect of 1-methylnicotinamide (MNA).
Topics: Aging; Animals; Anti-Inflammatory Agents; Brain; Brain Chemistry; Electrophoresis, Polyacrylamide Gel; Hypoxia-Ischemia, Brain; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinases; Niacinamide; Nicotinic Agonists; Rats; Rats, Wistar | 2008 |
Adipose tissue as a source of nicotinamide N-methyltransferase and homocysteine.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Adipose Tissue; Animals; Enzyme Inhibitors; Female; Gene Expression Regulation, Enzymologic; Homocysteine; Humans; Hypolipidemic Agents; Male; Mice; Mice, Inbred C57BL; Niacin; Niacinamide; Nicotinamide N-Methyltransferase; RNA, Messenger; Time Factors | 2009 |
1-methylnicotinamide (MNA) in prevention of diabetes-associated brain disorders.
Topics: Animals; Brain Diseases; Diabetes Mellitus, Experimental; Male; Niacinamide; Rats; Serotonin; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Streptozocin; Synaptosomes | 2010 |
Nicotinamide overload may play a role in the development of type 2 diabetes.
Topics: Adult; Aged; Aldehyde Oxidase; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Erythrocytes; Female; Humans; Hydrogen Peroxide; Insulin; Male; Middle Aged; NAD; Niacinamide; Oxidants; Random Allocation; Rats; Rats, Sprague-Dawley; Risk Factors; Sweat; Young Adult | 2009 |
The fluorescent condensation product of N1-methylnicotinamide and acetone; synthesis and properties.
Topics: Acetone; Coloring Agents; Fluorescence; Niacin; Niacinamide; Nicotinic Acids | 1947 |
The fluorescent condensation product of N1-methylnicotinamide and acetone; a sensitive method for the determination of N1-methylnicotinamide in urine.
Topics: Acetone; Coloring Agents; Fluorescence; Niacin; Niacinamide; Nicotinic Acids; Urine | 1947 |
The fluorescent condensation product of N1-methylnicotinamide and acetone; a rapid fluorometric method for the determination of the total pyridine nucleotides in the red blood cells.
Topics: Acetone; Erythrocytes; Fluorescence; Humans; Niacin; Niacinamide; Nucleotides; Pyridines | 1947 |
The isolation of the 6-pyridone of N1-methylnicotinamide from urine.
Topics: Benzimidazoles; Humans; Niacin; Niacinamide; Nicotinic Acids; Pyridones; Urine | 1947 |
The antipellagra action of N1-methylnicotinamide.
Topics: Humans; Niacin; Niacinamide; Nicotinic Acids; Pellagra | 1947 |
Effect of selected NAD+ analogues on mitochondria activity and proliferation of endothelial EA.hy926 cells.
Topics: Adenosine Triphosphate; Biological Transport; Calcium; Cell Cycle; Cell Line; Cell Proliferation; Cell Survival; Cytosol; Endothelial Cells; Humans; Membrane Potential, Mitochondrial; Mitochondria; NAD; Niacinamide; Oxygen; Pyridines; Pyridinium Compounds | 2010 |
[Effect of 1-methylnicotinamide on prooxidant-antioxidant balance parameters in rats during hepatic ischemia-reperfusion].
Topics: Animals; Antioxidants; Liver; Liver Diseases; Male; Niacinamide; Rats; Rats, Wistar; Reperfusion Injury | 2010 |
1-methylnicotinamide effects on the selected markers of endothelial function, inflammation and haemostasis in diabetic rats.
Topics: Animals; Biomarkers; Diabetes Mellitus; Endothelium, Vascular; Hemostasis; Hypolipidemic Agents; Inflammation; Male; Niacinamide; Rats; Rats, Sprague-Dawley; Survival Rate; Tumor Necrosis Factor-alpha; von Willebrand Factor | 2010 |
The fate of N1-methylnicotinamide in man.
Topics: Humans; Male; Niacin; Niacinamide; Nicotinic Acids; Pharmaceutical Preparations | 1945 |
Effect of tea beverages on aldehyde oxidase activity.
Topics: Aldehyde Oxidase; Animals; Beverages; Catechin; Cytosol; Herb-Drug Interactions; Humans; Liver; Male; Niacinamide; Rats; Tea; Xanthine Oxidase | 2011 |
¹H nuclear magnetic resonance based metabolic urinary profiling of patients with ischemic heart failure.
Topics: Acetic Acid; Acetone; Aged; Case-Control Studies; Cytosine; Energy Metabolism; Female; Glycine; Heart Failure, Systolic; Humans; Male; Metabolome; Metabolomics; Methylmalonic Acid; Multivariate Analysis; Myocardial Ischemia; Niacinamide; Nuclear Magnetic Resonance, Biomolecular; Protons; Urinalysis | 2011 |
The expression of nicotinamide N-methyltransferase increases ATP synthesis and protects SH-SY5Y neuroblastoma cells against the toxicity of Complex I inhibitors.
Topics: 1-Methyl-4-phenylpyridinium; Adenosine Triphosphate; Cell Line, Tumor; Electron Transport Complex I; Humans; NADH Dehydrogenase; Neuroblastoma; Niacinamide; Nicotinamide N-Methyltransferase | 2011 |
Effects of 1-methylnicotinamide and its metabolite N-methyl-2-pyridone-5-carboxamide on streptozotocin-induced toxicity in murine insulinoma MIN6 cell line.
Topics: Adenosine Triphosphate; Animals; Cell Line, Tumor; Cell Survival; Insulinoma; Mice; NAD; Niacinamide; Pyridones; Streptozocin | 2011 |
Excess nicotinamide inhibits methylation-mediated degradation of catecholamines in normotensives and hypertensives.
Topics: Adult; Betaine; Blood Pressure; Catecholamines; Female; Homocysteine; Humans; Hypertension; Indicators and Reagents; Male; Methylation; Niacinamide; Vitamins | 2012 |
N-Methyl-2-pyridone-5-carboxamide is 1-methylnicotinamide metabolite of low cyclooxygenase-dependent vasodilating activity.
Topics: Animals; Bradykinin; Human Umbilical Vein Endothelial Cells; Humans; Indomethacin; Male; Niacinamide; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Transfection; Vasodilation | 2012 |
Toxic effects of nicotinamide methylation on mouse brain striatum neuronal cells and its relation to manganese.
Topics: Animals; Cell Survival; Dithiothreitol; Manganese; Methylation; Mice; Neostriatum; Niacinamide; Nicotinamide N-Methyltransferase | 2012 |
Effects of N1-methylnicotinamide on oxidative and glycooxidative stress markers in rats with streptozotocin-induced diabetes mellitus.
Topics: Animals; Antioxidants; Biomarkers; Diabetes Mellitus, Experimental; DNA Damage; Drug Evaluation, Preclinical; Glycation End Products, Advanced; Lipid Peroxidation; Lipid Peroxides; Lymphocytes; Male; Niacinamide; Oxidation-Reduction; Oxidative Stress; Protein Carbonylation; Rats; Rats, Wistar; Streptozocin | 2012 |
Developmental changes of aldehyde oxidase activity and protein expression in human liver cytosol.
Topics: Adolescent; Adult; Aldehyde Oxidase; Child; Child, Preschool; Cytosol; Female; Humans; Infant; Infant, Newborn; Liver; Male; Middle Aged; Niacinamide; Oxidation-Reduction; Pyridones | 2012 |
Single bout of endurance exercise increases NNMT activity in the liver and MNA concentration in plasma; the role of IL-6.
Topics: Animals; Interleukin-6; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Niacinamide; Nicotinamide N-Methyltransferase; Physical Endurance; Swimming | 2012 |
Decreased skin-mediated detoxification contributes to oxidative stress and insulin resistance.
Topics: Animals; Antioxidants; Blood Glucose; Burns; Glycogen; Hydrogen Peroxide; Insulin; Insulin Resistance; Male; Niacinamide; Oxidative Stress; Rats; Rats, Sprague-Dawley; Skin; Xenobiotics | 2012 |
Excessive nicotinic acid increases methyl consumption and hydrogen peroxide generation in rats.
Topics: Animals; Dose-Response Relationship, Drug; Glucose; Glucose Tolerance Test; Glycogen; Hydrogen Peroxide; Insulin Resistance; Liver; Male; Muscle, Skeletal; Niacin; Niacinamide; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2013 |
Excess nicotinamide increases plasma serotonin and histamine levels.
Topics: Betaine; Choline; Chromatography, High Pressure Liquid; Histamine; Humans; Male; Niacinamide; Pyridones; Serotonin | 2013 |
HPLC-UV method for measuring nicotinamide N-methyltransferase activity in biological samples: evidence for substrate inhibition kinetics.
Topics: Animals; Chromatography, High Pressure Liquid; Enzyme Assays; Humans; Kinetics; Limit of Detection; Liver; Mice; Niacinamide; Nicotinamide N-Methyltransferase; Rabbits; Spectrophotometry, Ultraviolet | 2013 |
NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink.
Topics: Epigenesis, Genetic; Humans; Methionine; Methylation; Models, Genetic; Neoplasms; Niacinamide; Nicotinamide N-Methyltransferase | 2013 |
Nicotinamide supplementation induces detrimental metabolic and epigenetic changes in developing rats.
Topics: Animals; Betaine; Choline; CpG Islands; Dietary Supplements; DNA; DNA Damage; DNA Methylation; Epigenesis, Genetic; Glucose Intolerance; Homocysteine; Insulin Resistance; Liver; Male; Metabolic Diseases; Niacin; Niacinamide; Oxidative Stress; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Time Factors; Uracil; Vitamin B Complex; Weight Gain | 2013 |
Neuroprotective effects of nicotinamide N-methyltransferase and its metabolite 1-methylnicotinamide.
Topics: 2,4-Dinitrophenol; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Mitochondria; Neuroblastoma; Neuroprotective Agents; Niacinamide; Nicotinamide N-Methyltransferase; Oxidopamine; Potassium Cyanide; Rotenone | 2013 |
Nanomechanical sensing of the endothelial cell response to anti-inflammatory action of 1-methylnicotinamide chloride.
Topics: Actins; Anti-Inflammatory Agents; Calcium; Cells, Cultured; Elasticity; Endothelial Cells; Epoprostenol; Humans; Intracellular Space; Microscopy, Atomic Force; Nanotechnology; Niacinamide; Nitric Oxide; Tumor Necrosis Factor-alpha | 2013 |
Enzymes that control the conversion of L-tryptophan-nicotinamide and the urinary excretion ratio (N(1)-methyl-2-pyridone-5-carboxamide + N(1)-methyl-4-pyridone-3-carboxamide)/N(1)-methylnicotinamide in mice.
Topics: Animals; Body Weight; Eating; Enzymes; Male; Mice; NAD; Niacinamide; Pyridones; Quinolinic Acid; Tryptophan | 2013 |
Discovery and validation of urinary metabotypes for the diagnosis of hepatocellular carcinoma in West Africans.
Topics: Acetylcarnitine; Adolescent; Adult; Africa, Western; Aged; Aged, 80 and over; alpha-Fetoproteins; Biomarkers, Tumor; Carcinoma, Hepatocellular; Case-Control Studies; Choline; Creatine; Female; Humans; Ketoglutaric Acids; Liver Neoplasms; Male; Methionine; Middle Aged; Niacinamide; Phenotype; Reproducibility of Results; Sarcosine; Sensitivity and Specificity; Young Adult | 2014 |
Pharmacological doses of nicotinic acid and nicotinamide are independently metabolized in rats.
Topics: Animals; Diet; Drug Interactions; Male; Niacin; Niacinamide; Nicotinic Acids; Pyridones; Rats, Wistar | 2014 |
Simultaneous determination of N(1)-methylnicotinamide, L-carnitine, and creatinine in human plasma and urine by liquid chromatography with mass spectrometry for assessing the activities of multiple renal cationic transporters.
Topics: Carnitine; Chromatography, Liquid; Creatinine; Drug Stability; Female; Humans; Male; Mass Spectrometry; Niacinamide; Reproducibility of Results; Sensitivity and Specificity | 2014 |
Photoswitchable hydride transfer from iridium to 1-methylnicotinamide rationalized by thermochemical cycles.
Topics: Hydrogen; Iridium; Models, Molecular; Molecular Conformation; Niacinamide; Photochemical Processes; Temperature | 2014 |
Identification of a biochemical marker for endothelial dysfunction using Raman spectroscopy.
Topics: Animals; Aorta; Apolipoproteins E; Biomarkers; Endothelium, Vascular; Mice; Niacinamide; Phenylalanine; Spectrum Analysis, Raman; Tyrosine | 2015 |
Niacin metabolism and indoleamine 2,3-dioxygenase activation in malnourished patients with flaky paint dermatosis.
Topics: Acute-Phase Reaction; Adult; Aged; C-Reactive Protein; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Indoles; Kwashiorkor; Kynurenine; Middle Aged; Niacin; Niacinamide; Pellagra; Skin; Skin Diseases; Tryptophan | 2015 |
Lipid droplets formation in human endothelial cells in response to polyunsaturated fatty acids and 1-methyl-nicotinamide (MNA); confocal Raman imaging and fluorescence microscopy studies.
Topics: Aorta; Arachidonic Acid; Biological Transport; Cell Membrane; Eicosapentaenoic Acid; Endothelial Cells; Fatty Acids, Unsaturated; Humans; Lipid Droplets; Microscopy, Fluorescence; Niacinamide; Spectrum Analysis, Raman | 2016 |
Differential involvement of IL-6 in the early and late phase of 1-methylnicotinamide (MNA) release in Concanavalin A-induced hepatitis.
Topics: Acute-Phase Reaction; Aldehyde Oxidase; Animals; Chemical and Drug Induced Liver Injury; Concanavalin A; Cytokines; Energy Metabolism; Hepatitis; Hepatocytes; Interleukin-6; Liver Function Tests; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria, Liver; Niacinamide; Nicotinamide N-Methyltransferase | 2015 |
Serum N(1)-Methylnicotinamide Is Associated With Obesity and Diabetes in Chinese.
Topics: Adult; Asian People; Body Mass Index; China; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Niacinamide; Obesity; Overweight | 2015 |
Effects of 1-Methylnicotinamide (MNA) on Exercise Capacity and Endothelial Response in Diabetic Mice.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Epoprostenol; Male; Mice; Niacinamide; Nitrates; Nitrites; Physical Exertion | 2015 |
Niacin (Vitamin B3) Supplementation in Patients with Serotonin-Producing Neuroendocrine Tumor.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Female; Humans; Male; Middle Aged; Neuroendocrine Tumors; Niacinamide; Serotonin; Tryptophan; Vitamin B Complex; Young Adult | 2016 |
1-Methylnicotinamide ameliorates lipotoxicity-induced oxidative stress and cell death in kidney proximal tubular cells.
Topics: Albumins; Animals; Blotting, Western; Disease Models, Animal; Fatty Acids, Nonesterified; Immunohistochemistry; Kidney Tubules, Proximal; Male; Mice; Mice, Inbred C57BL; Niacinamide; Nicotinamide N-Methyltransferase; Oxidative Stress; Proteinuria; Real-Time Polymerase Chain Reaction; RNA, Small Interfering; Transfection | 2015 |
The effect of foetal bovine serum supplementation upon the lactate dehydrogenase cytotoxicity assay: Important considerations for in vitro toxicity analysis.
Topics: Adenosine Triphosphate; Animals; Carbolines; Cattle; Cell Line; Cell Survival; Culture Media; Humans; L-Lactate Dehydrogenase; Niacinamide; Rats; Toxicity Tests | 2015 |
The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition.
Topics: Animals; Blotting, Western; Cell Differentiation; Cells, Cultured; Embryonic Stem Cells; Epigenesis, Genetic; Gas Chromatography-Mass Spectrometry; Gene Expression Profiling; Gene Knockdown Techniques; Histones; Human Embryonic Stem Cells; Humans; Lysine; Mass Spectrometry; Metabolome; Metabolomics; Methylation; Mice; Niacinamide; Nicotinamide N-Methyltransferase; Proteomics; Reverse Transcriptase Polymerase Chain Reaction; S-Adenosylmethionine; Signal Transduction | 2015 |
Antiatherosclerotic Effects of 1-Methylnicotinamide in Apolipoprotein E/Low-Density Lipoprotein Receptor-Deficient Mice: A Comparison with Nicotinic Acid.
Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Female; Mice; Mice, Inbred C57BL; Mice, Knockout; Niacin; Niacinamide; Organ Culture Techniques; Receptors, LDL; Treatment Outcome | 2016 |
1-methylnicotinamide and its structural analog 1,4-dimethylpyridine for the prevention of cancer metastasis.
Topics: Animals; Cadherins; Cdh1 Proteins; Cell Line, Tumor; Epoprostenol; Female; Gene Expression Regulation, Neoplastic; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Niacinamide; Pyridinium Compounds; Xenograft Model Antitumor Assays | 2016 |
Activation of the nicotinamide N-methyltransferase (NNMT)-1-methylnicotinamide (MNA) pathway in pulmonary hypertension.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Animals; Case-Control Studies; Disease Models, Animal; Disease Progression; Endothelin-1; Epoprostenol; Female; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Liver; Lung; Male; Middle Aged; Monocrotaline; Niacinamide; Nicotinamide N-Methyltransferase; Nitric Oxide; Rats, Wistar; Signal Transduction; Time Factors; Ventricular Dysfunction, Right; Ventricular Function, Right | 2016 |
Serum N1-Methylnicotinamide is Associated With Coronary Artery Disease in Chinese Patients.
Topics: Aged; Biomarkers; Body Mass Index; China; Chromatography, Liquid; Comorbidity; Coronary Angiography; Coronary Artery Disease; Diabetes Mellitus; Female; Humans; Male; Mass Spectrometry; Middle Aged; Niacinamide; Nicotinamide N-Methyltransferase; Obesity; Reproducibility of Results; Retrospective Studies; Severity of Illness Index | 2017 |
The effects of 1,4-dimethylpyridine in metastatic prostate cancer in mice.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Disease Models, Animal; Docetaxel; Humans; Male; Mice; Neoplasm Metastasis; Niacinamide; Prostatic Neoplasms; Pyridines; Taxoids | 2017 |
Direct Comparison of the Enzymatic Characteristics and Superoxide Production of the Four Aldehyde Oxidase Enzymes Present in Mouse.
Topics: Aldehyde Oxidase; Aldehydes; Animals; Benzaldehydes; Catalysis; Catalytic Domain; Cinnamates; Kinetics; Mice; Mice, Inbred C57BL; Niacinamide; Substrate Specificity; Superoxides | 2017 |
Crystal structures of monkey and mouse nicotinamide N-methyltransferase (NNMT) bound with end product, 1-methyl nicotinamide.
Topics: Amino Acid Sequence; Animals; Catalytic Domain; Cloning, Molecular; Crystallography, X-Ray; Escherichia coli; Feedback, Physiological; Gene Expression; Macaca mulatta; Mice; Models, Molecular; Niacinamide; Nicotinamide N-Methyltransferase; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein Structure, Tertiary; Recombinant Proteins; S-Adenosylmethionine; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity | 2017 |
N
Topics: Adult; Body Mass Index; Caloric Restriction; Cells, Cultured; Energy Metabolism; Exercise; Exercise Therapy; Humans; Lipid Metabolism; Male; Middle Aged; Muscle Fibers, Skeletal; Muscle, Skeletal; Niacinamide; Nicotinamide N-Methyltransferase; Obesity; Signal Transduction; Sweden; Transcriptome; Up-Regulation | 2018 |
Cardioprotective effect of N-methylnicotinamide salt of pyruvate in experimental model of cardiac hypoxia.
Topics: Animals; Apolipoproteins E; Cardiotonic Agents; Creatine Kinase; Electrocardiography; Heart; Hypoxia; Male; Mice; Mice, Inbred C57BL; Models, Theoretical; Myocardial Infarction; Myocardium; Niacinamide; Pyruvic Acid; Receptors, LDL; Sodium Chloride; Troponin T | 2018 |
LC-MS/MS assay for N
Topics: Area Under Curve; Biomarkers, Pharmacological; Chromatography, Liquid; Data Accuracy; Drug Interactions; Humans; Hydrophobic and Hydrophilic Interactions; Kidney; Niacinamide; Organic Cation Transporter 2; Placebos; Reference Standards; Tandem Mass Spectrometry | 2018 |
Serum N
Topics: Aged; Asian People; China; Chromatography, Liquid; Coronary Artery Disease; Echocardiography, Doppler; Female; Heart Ventricles; Humans; Male; Middle Aged; Niacinamide; Nicotinamide N-Methyltransferase; Stroke Volume; Tandem Mass Spectrometry; Ventricular Dysfunction, Left | 2018 |
Intestinal barrier regulates immune responses in the liver via IL-10-producing macrophages.
Topics: Animals; Chemical and Drug Induced Liver Injury; Colitis; Concanavalin A; Dextran Sulfate; Disease Models, Animal; Female; Gastrointestinal Microbiome; Hepatitis; Interleukin-10; Liver; Macrophages; Male; Mice; Mice, Inbred C57BL; Niacinamide; T-Lymphocytes | 2018 |
Alleviation of fatty liver in a rat model by enhancing N
Topics: Aldehyde Oxidase; Animals; Biological Availability; Cytosol; Disease Models, Animal; Enzyme Inhibitors; Female; Humans; Hydralazine; Inhibitory Concentration 50; Liver; Liver Cirrhosis; Male; Niacinamide; Nicotinamide N-Methyltransferase; Rats, Sprague-Dawley | 2018 |
NAD metabolites interfere with proliferation and functional properties of THP-1 cells.
Topics: Antigens, Differentiation; Cell Cycle; Cell Proliferation; Chemokines; Humans; Lipopolysaccharides; Monocytes; NAD; Niacinamide; Poly (ADP-Ribose) Polymerase-1; Pyridinium Compounds; Reactive Oxygen Species; Sirtuin 1; THP-1 Cells; Tumor Necrosis Factor-alpha | 2019 |
1-Methylnicotinamide attenuates lipopolysaccharide-induced cognitive deficits via targeting neuroinflammation and neuronal apoptosis.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Cognition Disorders; Frontal Lobe; Hippocampus; Interleukin-6; Lipopolysaccharides; Male; Memory Disorders; Mice, Inbred ICR; Neurons; Neuroprotective Agents; Niacinamide; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2019 |
A Noninvasive Urine Metabolome Panel as Potential Biomarkers for Diagnosis of T Cell-Mediated Renal Transplant Rejection.
Topics: Acute Disease; Adenosine Diphosphate; Adult; Biomarkers; Cholesterol Esters; Cross-Sectional Studies; Female; gamma-Aminobutyric Acid; Graft Rejection; Graft Survival; Hippurates; Humans; Kidney Transplantation; Male; Metabolome; Middle Aged; NAD; Niacin; Niacinamide; Proline; Renal Insufficiency, Chronic; ROC Curve; Spermidine; T-Lymphocytes | 2020 |
N
Topics: Acetylation; Animals; Blood Glucose; Cell Line; Diabetes Mellitus, Type 2; Forkhead Box Protein O1; Insulin; Insulin Resistance; Lipid Metabolism; Liver; Male; Mice; Niacinamide; Obesity; Sirtuin 1 | 2020 |
Nicotinamide and its metabolite N1-Methylnicotinamide alleviate endocrine and metabolic abnormalities in adipose and ovarian tissues in rat model of Polycystic Ovary Syndrome.
Topics: Adipose Tissue; AMP-Activated Protein Kinases; Animals; Cytokines; Estrous Cycle; Female; Gene Expression; Glucose Transporter Type 4; Hyperandrogenism; Luteinizing Hormone; Metformin; Niacinamide; Nicotinamide Phosphoribosyltransferase; Ovary; Polycystic Ovary Syndrome; Rats, Wistar; Resistin; Steroid 17-alpha-Hydroxylase; Testosterone | 2020 |
Drug-Drug Interactions Involving Renal OCT2/MATE Transporters: Clinical Risk Assessment May Require Endogenous Biomarker-Informed Approach.
Topics: Acidosis, Lactic; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Antiviral Agents; Area Under Curve; Biomarkers; Creatinine; Drug Interactions; HEK293 Cells; Histamine H2 Antagonists; Humans; Hypoglycemic Agents; In Vitro Techniques; Metformin; Niacinamide; Organic Cation Transport Proteins; Organic Cation Transporter 2; Proton Pump Inhibitors; Renal Elimination | 2021 |
Antidepressant-like effects of 1-methylnicotinamide in a chronic unpredictable mild stress model of depression.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Chronic Disease; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Hindlimb Suspension; Hippocampus; Male; Mice; Mice, Inbred C57BL; Niacinamide; Stress, Psychological | 2021 |
Dual Analysis of N-methyl-2-pyridone-5-carboxamide and N-1-methylnicotinamide in Urine by HPLC with UV Detection.
Topics: Chromatography, High Pressure Liquid; Niacinamide; Pyridones | 2021 |
1-Methylnicotinamide is an immune regulatory metabolite in human ovarian cancer.
Topics: Ascites; Female; Humans; Niacinamide; Ovarian Neoplasms; Tumor Microenvironment | 2021 |
N1‑methylnicotinamide ameliorates insulin resistance in skeletal muscle of type 2 diabetic mice by activating the SIRT1/PGC‑1α signaling pathway.
Topics: Animals; Cell Line; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Insulin Receptor Substrate Proteins; Insulin Resistance; Mice, Inbred C57BL; Muscle, Skeletal; Myoblasts; Niacinamide; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Sirtuin 1 | 2021 |
Diagnostic Value of Serum N1-Methylnicotinamide in Cervical Cancer Patients.
Topics: Antigens, Neoplasm; Biomarkers, Tumor; Female; Humans; Lymphatic Metastasis; Niacinamide; Prognosis; Serpins; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms | 2021 |
Potent Inhibition of Nicotinamide
Topics: Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Molecular Structure; Niacinamide; Nicotinamide N-Methyltransferase; Protein Binding; Structure-Activity Relationship | 2021 |
Urinary metabolomics of HCV patients with severe liver fibrosis before and during the sustained virologic response achieved by direct acting antiviral treatment.
Topics: Aged; Antiviral Agents; Biomarkers; Hepatitis C; Humans; Hydroxybutyrates; Liver Cirrhosis; Male; Metabolome; Metabolomics; Middle Aged; Niacinamide; Predictive Value of Tests; Proton Magnetic Resonance Spectroscopy; Severity of Illness Index; Sustained Virologic Response; Time Factors; Treatment Outcome; Urinalysis | 2021 |
Nicotinamide N-methyltransferase ameliorates renal fibrosis by its metabolite 1-methylnicotinamide inhibiting the TGF-β1/Smad3 pathway.
Topics: Animals; Cells, Cultured; Fibrosis; Kidney; Male; Mice; Mice, Inbred C57BL; Niacinamide; Nicotinamide N-Methyltransferase; Renal Insufficiency, Chronic; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta1; Ureteral Obstruction | 2022 |
N1-Methylnicotinamide: The Mysterious Anti-aging Actor in Renal Transplantation.
Topics: Aged; Aging; Humans; Kidney; Kidney Transplantation; Niacinamide; Vitamins | 2023 |
Nicotinamide-N-methyltransferase regulates lipid metabolism via SAM and 1-methylnicotinamide in the AML12 hepatocyte cell line.
Topics: Animals; Cell Line; Hepatocytes; Lipid Metabolism; Lipids; Methyltransferases; Mice; Niacinamide | 2023 |
1-Methylnicotinamide (1-MNA) inhibits the activation of the NLRP3 inflammasome in human macrophages.
Topics: Caspase 1; Humans; Hydrogen Peroxide; Inflammasomes; Interleukin-1beta; Macrophages; Niacinamide; NLR Family, Pyrin Domain-Containing 3 Protein; Reactive Oxygen Species | 2023 |