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n(1)-ethyl-n-(11)-((cyclopropyl)methyl)-4,8-diazaundecane-1,11-diamine and putrescine

n(1)-ethyl-n-(11)-((cyclopropyl)methyl)-4,8-diazaundecane-1,11-diamine has been researched along with putrescine in 3 studies

*Putrescine: A toxic diamine formed by putrefaction from the decarboxylation of arginine and ornithine. [MeSH]

*Putrescine: A toxic diamine formed by putrefaction from the decarboxylation of arginine and ornithine. [MeSH]

Compound Research Comparison

Studies
(n(1)-ethyl-n-(11)-((cyclopropyl)methyl)-4,8-diazaundecane-1,11-diamine)
Trials
(n(1)-ethyl-n-(11)-((cyclopropyl)methyl)-4,8-diazaundecane-1,11-diamine)
Recent Studies (post-2010)
(n(1)-ethyl-n-(11)-((cyclopropyl)methyl)-4,8-diazaundecane-1,11-diamine)
Studies
(putrescine)
Trials
(putrescine)
Recent Studies (post-2010) (putrescine)
14004,64327826

Protein Interaction Comparison

ProteinTaxonomyn(1)-ethyl-n-(11)-((cyclopropyl)methyl)-4,8-diazaundecane-1,11-diamine (IC50)putrescine (IC50)
Chain A, S-ADENOSYLMETHIONINE DECARBOXYLASE ALPHA CHAINHomo sapiens (human)0.2001
Chain B, S-ADENOSYLMETHIONINE DECARBOXYLASE BETA CHAINHomo sapiens (human)0.2001
Chain A, S-ADENOSYLMETHIONINE DECARBOXYLASE ALPHA CHAINHomo sapiens (human)0.2001
Chain B, S-ADENOSYLMETHIONINE DECARBOXYLASE BETA CHAINHomo sapiens (human)0.2001

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Casero, RA; Ha, HC; Woster, PM; Yager, JD1
Casero, RA; Ha, HC; Woster, PA; Yager, JD1
Casero, RA; Davidson, NE; McCloskey, DE; Woster, PM1

Other Studies

3 other study(ies) available for n(1)-ethyl-n-(11)-((cyclopropyl)methyl)-4,8-diazaundecane-1,11-diamine and putrescine

ArticleYear
The role of polyamine catabolism in polyamine analogue-induced programmed cell death.
    Proceedings of the National Academy of Sciences of the United States of America, 1997, Oct-14, Volume: 94, Issue:21

    Topics: Acetyltransferases; Antineoplastic Agents; Antioxidants; Apoptosis; Carcinoma, Non-Small-Cell Lung; Catalase; DNA Fragmentation; DNA, Neoplasm; Humans; Lung Neoplasms; Oxidoreductases Acting on CH-NH Group Donors; Polyamines; Putrescine; Tumor Cells, Cultured

1997
Structural specificity of polyamines and polyamine analogues in the protection of DNA from strand breaks induced by reactive oxygen species.
    Biochemical and biophysical research communications, 1998, Mar-06, Volume: 244, Issue:1

    Topics: Antineoplastic Agents; Antioxidants; Bacteriophage phi X 174; Biogenic Polyamines; Copper; DNA Damage; Hydrogen Peroxide; Polyamines; Putrescine; Reactive Oxygen Species; Spermidine; Spermine; Structure-Activity Relationship

1998
Effects of the polyamine analogues N1-ethyl-N11-((cyclopropyl)methyl)-4,8-diazaundecane and N1-ethylN-11-((cycloheptyl)methyl)-4,8-diazaundecane in human prostate cancer cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Cell Division; DNA Fragmentation; Humans; Kinetics; Male; Polyamines; Propylamines; Prostatic Neoplasms; Putrescine; Spermidine; Spermine; Tumor Cells, Cultured

2000