Page last updated: 2024-09-03

myxochelin a and lysine

myxochelin a has been researched along with lysine in 17 studies

Compound Research Comparison

Studies
(myxochelin a)
Trials
(myxochelin a)
Recent Studies (post-2010)
(myxochelin a)
Studies
(lysine)
Trials
(lysine)
Recent Studies (post-2010) (lysine)
1701137,44962211,213

Protein Interaction Comparison

ProteinTaxonomymyxochelin a (IC50)lysine (IC50)
Cationic amino acid transporter 3Homo sapiens (human)158

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.88)18.7374
1990's0 (0.00)18.2507
2000's5 (29.41)29.6817
2010's7 (41.18)24.3611
2020's4 (23.53)2.80

Authors

AuthorsStudies
Bedorf, N; Höfle, G; Kohl, W; Kunze, B; Reichenbach, H1
Blöcker, H; Höfle, G; Kunze, B; Müller, R; Nordsiek, G; Silakowski, B1
Gaitatzis, N; Kunze, B; Müller, R1
Fujita, T; Furumai, T; Igarashi, Y; Miyanaga, S; Obata, T; Onaka, H; Saiki, I; Saito, N; Sakurai, H1
Li, Y; Müller, R; Weissman, KJ1
Igarashi, Y; Miyanaga, S; Onaka, H; Saiki, I; Sakurai, H1
Dahse, HM; Koeberle, A; König, S; Nett, M; Schieferdecker, S; Werz, O1
Dahse, HM; König, GM; König, S; Korp, J; Nett, M; Schieferdecker, S; Werz, O1
Findlay, BL1
König, S; Nett, M; Pace, S; Schieferdecker, S; Werz, O1
Kelleher, NL; McClure, RA; Mullowney, MW; Robey, MT; Thomson, RJ1
Korp, J; Nett, M; Sester, A; Winand, L1
Hiller, W; Nett, M; Pace, S; Sester, A; Werz, O; Winand, L1
Ajdidi, A; El-Nakady, YA; Izzat, S; Liu, XX; Müller, R; Rachid, S; Ye, BC1
Hubmann, G; Lütz, S; Rosenthal, K; Schwarz, J1
Akone, SH; Frank, NA; Frewert, S; Hamed, MM; Herrmann, J; Hirsch, AKH; Hüttel, S; Müller, R; Rasheed, S; Schuler, SMM; Széles, M1
Gao, DF; Li, YZ; Lin, ZM; Niu, L; Sui, HY; Wang, DG; Wang, JJ; Wu, C1

Reviews

2 review(s) available for myxochelin a and lysine

ArticleYear
The Chemical Ecology of Predatory Soil Bacteria.
    ACS chemical biology, 2016, 06-17, Volume: 11, Issue:6

    Topics: Anti-Bacterial Agents; Antibiosis; Biofilms; Biological Products; Ecology; Electron Transport; Lipoxygenase Inhibitors; Lysine; Macrolides; Myxococcus xanthus; Quorum Sensing; Secondary Metabolism; Siderophores; Soil Microbiology

2016
Natural products from thioester reductase containing biosynthetic pathways.
    Natural product reports, 2018, 09-19, Volume: 35, Issue:9

    Topics: Alkaloids; Azabicyclo Compounds; Benzodiazepinones; Biological Products; Biosynthetic Pathways; Cyclization; Depsipeptides; Dipeptides; Indoles; Lactams; Leupeptins; Lysine; Multigene Family; Peptide Synthases; Polyketide Synthases; Protein Domains

2018

Other Studies

15 other study(ies) available for myxochelin a and lysine

ArticleYear
Myxochelin A, a new iron-chelating compound from Angiococcus disciformis (Myxobacterales). Production, isolation, physico-chemical and biological properties.
    The Journal of antibiotics, 1989, Volume: 42, Issue:1

    Topics: Chemical Phenomena; Chemistry; Iron Chelating Agents; Lysine; Microbial Sensitivity Tests; Myxococcales

1989
The myxochelin iron transport regulon of the myxobacterium Stigmatella aurantiaca Sg a15.
    European journal of biochemistry, 2000, Volume: 267, Issue:21

    Topics: Amino Acid Sequence; Biological Transport; Chromatography, High Pressure Liquid; Conserved Sequence; Gene Expression Regulation, Bacterial; Hydroxybenzoates; Intramolecular Transferases; Iron; Iron Chelating Agents; Lysine; Molecular Sequence Data; Multigene Family; Mutation; Operon; Protein Structure, Tertiary; Regulatory Sequences, Nucleic Acid; Regulon; Sequence Alignment; Stigmatella aurantiaca

2000
In vitro reconstitution of the myxochelin biosynthetic machinery of Stigmatella aurantiaca Sg a15: Biochemical characterization of a reductive release mechanism from nonribosomal peptide synthetases.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Sep-25, Volume: 98, Issue:20

    Topics: Amino Acid Sequence; Bacterial Proteins; Catechols; Cloning, Molecular; DNA-Binding Proteins; Escherichia coli; Hydrolases; Lysine; Molecular Sequence Data; Molecular Structure; Multigene Family; Nucleotidyltransferases; Oxidation-Reduction; Peptide Synthases; Protein Processing, Post-Translational; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Stigmatella aurantiaca

2001
Absolute configuration and antitumor activity of myxochelin A produced by Nonomuraea pusilla TP-A0861.
    The Journal of antibiotics, 2006, Volume: 59, Issue:11

    Topics: Actinobacteria; Animals; Antineoplastic Agents; Cell Adhesion; Cell Line, Tumor; Cell Movement; Colonic Neoplasms; Lysine; Mice; Microscopy, Electron, Scanning; Nuclear Magnetic Resonance, Biomolecular; Spectrometry, Mass, Fast Atom Bombardment; Stereoisomerism

2006
Myxochelin biosynthesis: direct evidence for two- and four-electron reduction of a carrier protein-bound thioester.
    Journal of the American Chemical Society, 2008, Jun-18, Volume: 130, Issue:24

    Topics: Bacterial Proteins; Catechols; Electrons; Fluorobenzenes; Hydrolases; Hydroxybenzoates; Lysine; Nucleotidyltransferases; Oxidation-Reduction; Oximes; Recombinant Proteins

2008
Synthesis and evaluation of myxochelin analogues as antimetastatic agents.
    Bioorganic & medicinal chemistry, 2009, Apr-01, Volume: 17, Issue:7

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Catechols; Cell Line, Tumor; Lung Neoplasms; Lysine; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Neoplasm Metastasis; Stereoisomerism; Structure-Activity Relationship

2009
Myxochelins target human 5-lipoxygenase.
    Journal of natural products, 2015, Feb-27, Volume: 78, Issue:2

    Topics: Arachidonate 5-Lipoxygenase; Curcumin; HeLa Cells; Humans; K562 Cells; Lipoxygenase Inhibitors; Lysine; Molecular Structure; Myxococcales; Siderophores; Stereoisomerism

2015
Harnessing Enzymatic Promiscuity in Myxochelin Biosynthesis for the Production of 5-Lipoxygenase Inhibitors.
    Chembiochem : a European journal of chemical biology, 2015, Volume: 16, Issue:17

    Topics: Arachidonate 5-Lipoxygenase; Humans; Inhibitory Concentration 50; Lipoxygenase Inhibitors; Lysine; Myxococcales; Protein Binding; Structure-Activity Relationship

2015
Myxochelin-Inspired 5-Lipoxygenase Inhibitors: Synthesis and Biological Evaluation.
    ChemMedChem, 2017, 01-05, Volume: 12, Issue:1

    Topics: Arachidonate 5-Lipoxygenase; Biological Products; Cell-Free System; Dose-Response Relationship, Drug; Escherichia coli; Humans; Lipoxygenase Inhibitors; Lysine; Molecular Structure; Neutrophils; Structure-Activity Relationship

2017
Engineering Pseudochelin Production in Myxococcus xanthus.
    Applied and environmental microbiology, 2018, 11-15, Volume: 84, Issue:22

    Topics: Amidohydrolases; Bacterial Proteins; Biosynthetic Pathways; Catechols; Gene Expression Regulation, Bacterial; Genetic Engineering; Lysine; Myxococcus xanthus; Plasmids; Promoter Regions, Genetic; Regulon

2018
Myxochelin- and Pseudochelin-Derived Lipoxygenase Inhibitors from a Genetically Engineered
    Journal of natural products, 2019, 09-27, Volume: 82, Issue:9

    Topics: Bacterial Proteins; Catechols; Genetic Engineering; Humans; Lipoxygenase Inhibitors; Lysine; Myxococcus xanthus

2019
The ROK like protein of Myxococcus xanthus DK1622 acts as a pleiotropic transcriptional regulator for secondary metabolism.
    Journal of biotechnology, 2020, Mar-10, Volume: 311

    Topics: Bacterial Proteins; Electrophoresis, Gel, Two-Dimensional; Gene Expression Regulation; Gene Expression Regulation, Bacterial; Lysine; Myxococcus xanthus; Polyenes; Promoter Regions, Genetic; Proteomics; Secondary Metabolism

2020
Triaging of Culture Conditions for Enhanced Secondary Metabolite Diversity from Different Bacteria.
    Biomolecules, 2021, 01-30, Volume: 11, Issue:2

    Topics: Bacillus amyloliquefaciens; Culture Media; Data Mining; Deferoxamine; Genome; Lysine; Microbial Sensitivity Tests; Multigene Family; Myxococcales; Oligopeptides; Rhodococcus; Secondary Metabolism; Streptomyces

2021
Expanding the Myxochelin Natural Product Family by Nicotinic Acid Containing Congeners.
    Molecules (Basel, Switzerland), 2021, Aug-14, Volume: 26, Issue:16

    Topics: Biological Products; Biosynthetic Pathways; Genome, Bacterial; Lysine; Metabolome; Myxococcales; Niacin

2021
The Discovery and Biosynthesis of Nicotinic Myxochelins from an
    Journal of natural products, 2021, 10-22, Volume: 84, Issue:10

    Topics: Biological Products; Lysine; Molecular Structure; Multigene Family; Myxococcales

2021