mycobactin has been researched along with thiazoline-2-thione* in 1 studies
1 other study(ies) available for mycobactin and thiazoline-2-thione
Article | Year |
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Synthesis and stereochemical assignment of brasilibactin A.
[structure: see text] Brasilibactin A, a naturally occurring siderophore related to the mycobactins, has been synthesized in six steps. Use of asymmetric titanium-mediated aldol reactions allowed the preparation of both diastereomers from a common synthetic intermediate, thus allowing the relative stereochemistry of the natural product to be assigned. Brasilibactin A exhibits no inhibition of histone deacetylases (HDACs) in spite of the N-formyl-N-hydroxy lysine moiety that is expected to affect the activity of these metal-dependent lysine-modifying enzymes. Topics: Amides; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Hydroxylation; Lysine; Metals; Molecular Structure; Oxazoles; Stearic Acids; Stereoisomerism; Thiazolidines | 2007 |