mycaminosyltylonolide has been researched along with 4--deoxymycaminosyltylonolide* in 2 studies
2 other study(ies) available for mycaminosyltylonolide and 4--deoxymycaminosyltylonolide
| Article | Year |
|---|---|
Syntheses of 23-deoxy-23-N-ethyl-23-(2-fluoro-, 2,2-difluoro-, and 2,2,2-trifluoroethyl)amino derivatives of mycaminosyl tylonolide and 4'-deoxymycaminosyl tylonolide.
Derivatives of mycaminosyl tylonolide (1) and 4'-deoxymycaminosyl tylonolide (2) containing N-ethyl-2-fluoro-, 2,2-difluoro- and 2,2,2-trifluoroethylamino groups at their C-23 have been prepared by treating 23-deoxy-23-ethylaminomycaminosyl tylonolide diethyl acetal (14) and its 4'-deoxy analog 15 with 2-fluoro-, 2,2-difluoro- and 2,2,2-trifluoroethyl trifluoromethanesulfonates. The relationship between the antibacterial activity and the numbers of the fluorine atoms introduced in the final products is discussed. Topics: Leucomycins; Tylosin | 1984 |
Syntheses of derivatives of 4'-deoxymycaminosyl tylonolide and mycaminosyl tylonolide modified AT C-23.
Topics: Anti-Bacterial Agents; Bacteria; Leucomycins; Structure-Activity Relationship; Tylosin | 1981 |