my 5445 and zaprinast

my 5445 has been researched along with zaprinast in 8 studies

Research

Studies (8)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (37.50)	18.7374
1990's	3 (37.50)	18.2507
2000's	1 (12.50)	29.6817
2010's	1 (12.50)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bristol, JA; Cain, MH; Weishaar, RE	1
Frierson, MR; Kondo, K; Konishi, Y; Lee, SJ; Macina, OT; Miskowski, TA; Riviello, CM; Sircar, JC; Sugitani, M; Yu, DT	1
Arch, JR; Buckle, DR; Connolly, BJ; Fenwick, AE; Foster, KA; Murray, KJ; Readshaw, SA; Smallridge, M; Smith, DG	1
Fujimoto, M; Saeki, T; Saito, I; Takase, Y	1
Barrot, M; Bihel, F; Bollenbach, M; Bourguignon, JJ; Kremer, M; Lugnier, C; Megat, S; Salvat, E; Schmitt, M	1
Brazdil, R; Diocee, BK; Jordan, R; Souness, JE	1
Moncada, S; Palmer, RM; Radomski, MW	1
Barile, L; Giacomello, A; Lupi, F; Messina, E	1

Reviews

1 review(s) available for my 5445 and zaprinast

Article	Year
A new generation of phosphodiesterase inhibitors: multiple molecular forms of phosphodiesterase and the potential for drug selectivity. Journal of medicinal chemistry, 1985, Volume: 28, Issue:5 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Blood Platelets; Calmodulin; Cardiotonic Agents; Guinea Pigs; Humans; Hypersensitivity; In Vitro Techniques; Lung Diseases; Myocardium; Platelet Aggregation; Substrate Specificity	1985

Article

Year

A new generation of phosphodiesterase inhibitors: multiple molecular forms of phosphodiesterase and the potential for drug selectivity.

Journal of medicinal chemistry, 1985, Volume: 28, Issue:5

Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Blood Platelets; Calmodulin; Cardiotonic Agents; Guinea Pigs; Humans; Hypersensitivity; In Vitro Techniques; Lung Diseases; Myocardium; Platelet Aggregation; Substrate Specificity

1985

Other Studies

7 other study(ies) available for my 5445 and zaprinast

Article	Year
Discovery of potent cyclic GMP phosphodiesterase inhibitors. 2-Pyridyl- and 2-imidazolylquinazolines possessing cyclic GMP phosphodiesterase and thromboxane synthesis inhibitory activities. Journal of medicinal chemistry, 1995, Sep-01, Volume: 38, Issue:18 Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adult; Animals; Blood Platelets; Cattle; Cells, Cultured; Cyclooxygenase Inhibitors; Humans; Male; Quinazolines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thromboxane A2; Thromboxane-A Synthase	1995
Inhibition of cyclic nucleotide phosphodiesterase by derivatives of 1,3-bis(cyclopropylmethyl)xanthine. Journal of medicinal chemistry, 1994, Feb-18, Volume: 37, Issue:4 Topics: Adenosine; Alkylation; Animals; Binding Sites; Brain; Male; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Rolipram; Structure-Activity Relationship; Xanthines	1994
Cyclic GMP phosphodiesterase inhibitors. 1. The discovery of a novel potent inhibitor, 4-((3,4-(methylenedioxy)benzyl)amino)-6,7,8-trimethoxyquinazoline. Journal of medicinal chemistry, 1993, Nov-26, Volume: 36, Issue:24 Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Aorta; Chromones; Coronary Vessels; Cyclic GMP; Dinoprost; Isoenzymes; Molecular Structure; Muscle Relaxation; Purinones; Quinazolines; Structure-Activity Relationship; Swine	1993
Design and synthesis of 3-aminophthalazine derivatives and structural analogues as PDE5 inhibitors: anti-allodynic effect against neuropathic pain in a mouse model. European journal of medicinal chemistry, 2019, Sep-01, Volume: 177 Topics: Analgesics; Animals; Hyperalgesia; Male; Mice, Inbred C57BL; Molecular Structure; Neuralgia; Phosphodiesterase 5 Inhibitors; Phthalazines; Solubility; Structure-Activity Relationship	2019
Role of selective cyclic GMP phosphodiesterase inhibition in the myorelaxant actions of M&B 22,948, MY-5445, vinpocetine and 1-methyl-3-isobutyl-8-(methylamino)xanthine. British journal of pharmacology, 1989, Volume: 98, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Aorta, Thoracic; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Kinetics; Male; Methylene Blue; Muscle Relaxants, Central; Nitric Oxide; Phthalazines; Purinones; Pyridazines; Rats; Rats, Inbred Strains; Theophylline; Vinca Alkaloids	1989
The role of nitric oxide and cGMP in platelet adhesion to vascular endothelium. Biochemical and biophysical research communications, 1987, Nov-13, Volume: 148, Issue:3 Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Aspirin; Blood Platelets; Collagen; Cyclic GMP; Endothelium, Vascular; Epoprostenol; Extracellular Matrix; Humans; In Vitro Techniques; Nitric Oxide; Phthalazines; Platelet Adhesiveness; Purinones; Superoxide Dismutase; Thrombin	1987
Cyclic nucleotides and neuroblastoma differentiation. Nucleosides, nucleotides & nucleic acids, 2004, Volume: 23, Issue:8-9 Topics: Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cyclic AMP; Cyclic GMP; Dipyridamole; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Neuroblastoma; Nucleotides, Cyclic; Phosphodiesterase Inhibitors; Phthalazines; Purinones; Time Factors	2004