muscimol has been researched along with sr 95531 in 70 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.43) | 18.7374 |
| 1990's | 22 (31.43) | 18.2507 |
| 2000's | 29 (41.43) | 29.6817 |
| 2010's | 16 (22.86) | 24.3611 |
| 2020's | 2 (2.86) | 2.80 |
| Authors | Studies |
|---|---|
| Chambon, JP; Melikian, A; Schlewer, G; Wermuth, CG | 1 |
| Chebib, M; Johnston, GA | 1 |
| Engblom, C; Frølund, B; Kristiansen, U; Krogsgaard-Larsen, P; Liljefors, T; Stensbøl, TB; Tagmose, L | 1 |
| Scarth, BA; Shaw, C | 2 |
| Banerjee, PK; Depaulis, A; Hechler, V; Snead, OC; Vergnes, M | 1 |
| Asami, S; Doi, M; Fukuda, H; Ito, Y; Koshiba, T; Murakoshi, Y | 1 |
| Harris, RA; Leidenheimer, NJ | 1 |
| Balcar, VJ | 1 |
| Farb, DH; Farrant, M; Roca, DJ; Rozenberg, I | 1 |
| Catt, KJ; Stojilković, SS; Virmani, MA | 1 |
| Maksay, G | 2 |
| Browning, MD; Dunwiddie, TV; Hahner, LD; Harris, RA; Leidenheimer, NJ | 1 |
| Debnath, ML; Klunk, WE; McClure, RJ; Pettegrew, JW | 1 |
| Basile, AS; Harris, BD; Moody, EJ; Skolnick, P | 1 |
| Lukasiewicz, PD; Maple, BR; Werblin, FS | 1 |
| Ito, Y | 1 |
| Korpi, ER; Lüddens, H; Wong, G | 1 |
| Choi, SR; Choi, YS; Kim, YH; Song, DK; Suh, HW | 1 |
| Bahn, S; Jones, A; Korpi, ER; Mäkelä, R; McKernan, RM; Mellor, JR; Nusser, Z; Pelz, R; Pollard, S; Randall, AD; Sieghart, W; Smith, AJ; Somogyi, P; Stephenson, FA; Wisden, W | 1 |
| Akahane, K; Fukuda, H; Ito, Y; Kimura, Y; Miyasaka, T | 1 |
| Chen, F; Jarrott, B; Lawrence, AJ; Rezvani, A | 1 |
| Choi, IG; Huh, SO; Ihn, BM; Jung, JS; Kim, YH; Song, DK; Suh, HW | 1 |
| Dzubay, JA; Jones, MV; Sahara, Y; Westbrook, GL | 1 |
| Huh, SO; Kim, YH; Lee, KC; Song, DK; Suh, HW | 1 |
| Maksay, G; McKernan, R | 1 |
| Jonas, P; Jones, MV; Sahara, Y; Westbrook, GL | 1 |
| Homanics, GE; Korpi, ER; Kralic, JE; Morrow, AL; O'Buckley, TK | 1 |
| Alonso, G; Duvoid, A; Hussy, N; Moos, F; Runquist, M | 1 |
| Darlington, CL; Gliddon, CM; Smith, PF | 1 |
| Ackerson, LC; Galvan, A; Maidment, NT; Smith, Y; Villalba, RM; West, SM; Wichmann, T | 1 |
| Akaike, N; Ito, Y; Jang, IS | 1 |
| Jorge, JC; Lathroum, L; Pérez-Acevedo, NL | 1 |
| Chiken, S; Kita, H; Nambu, A; Tachibana, Y | 1 |
| Jorge, JC; Morales-Crespo, L; Rivera-Arce, JC; Vargas-Pinto, N; Velázquez, KT | 1 |
| Kubin, L; Volgin, DV | 1 |
| Friedrich, RW; Li, J; Mack-Bucher, JA | 1 |
| Manabe, T; Nakamura, M; Sekino, Y | 1 |
| Jembrek, MJ; Pericić, D; Strac, DS; Vlainić, J | 1 |
| Heinrich, M; Milenković, I; Reinert, T; Rübsamen, R; Turecek, R; Witte, M | 1 |
| Osaka, T | 1 |
| Darbin, O; Wichmann, T | 1 |
| Gutiérrez, R; Heinemann, U; Romo-Parra, H; Treviño, M | 1 |
| Czajkowski, C; Sharkey, LM | 1 |
| Anseloni, VC; Gold, MS | 1 |
| Gross, GW; Rijal, SO | 1 |
| Grillner, S; Ménard, A | 1 |
| Aarum, J; Chuang, TT; Goffin, D; Jovanovic, JN; Schroeder, JE | 1 |
| Mandel, DA; Schreihofer, AM | 1 |
| Emala, CW; Gallos, G; Gleason, NR; Zhang, Y | 1 |
| Emala, CW; Gallos, G; Gleason, NR; Mizuta, K; Virag, L; Whittington, RA; Zhang, Y | 1 |
| Antal, K; Emri, Z; Katarova, Z; Máté, Z; Schwirtlich, M; Szabó, G | 1 |
| Bongianni, F; Cinelli, E; Mutolo, D; Pantaleo, T | 1 |
| Adelsberger, H; Chen, X; Henning, HA; Konnerth, A; Kovalchuk, Y; Ruth, P; Sausbier, M; Wietzorrek, G; Yarom, Y | 1 |
| Dubner, R; Guo, W; Lagraize, SC; Ren, K; Wei, F; Yang, K | 1 |
| Balmer, TS; Carrasco, MM; Mao, YT; Pallas, SL | 1 |
| Feller, MB; Hamby, AM; Wei, W; Zhou, K | 1 |
| Stell, BM | 1 |
| Arreto, CD; Bourgeais, L; Condes-Lara, M; Jay, T; Noseda, R; Robert, C; Villanueva, L | 1 |
| Dutheil, S; Escoffier, G; Gharbi, A; Tighilet, B; Watabe, I | 1 |
| Hamilton, TJ; Holcombe, A; Tresguerres, M | 1 |
| Allain, L; Gouzer, G; Shinoe, T; Specht, CG; Triller, A | 1 |
| Chee, SS; Dringenberg, HC; Menard, JL | 1 |
| Chitravanshi, VC; Kawabe, K; Sapru, HN | 1 |
| Bardoni, R; Betelli, C; MacDermott, AB | 1 |
| Gao, Y; Kosten, T; Li, DP; Zhou, JJ; Zhu, Y | 1 |
| Biscocho, D; Cook, JG; Leise, EM; Long, J; Shah, N | 1 |
| Bolding, KA; Ferbinteanu, J; Fox, SE; Muller, RU | 1 |
| Jiao, Y; Li, K; Li, Z; Xing, Y | 1 |
2 review(s) available for muscimol and sr 95531
| Article | Year |
|---|---|
GABA-Activated ligand gated ion channels: medicinal chemistry and molecular biology.
Topics: Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Ion Channels; Ligands; Receptors, GABA; Receptors, GABA-A; Structure-Activity Relationship | 2000 |
[Neurochemical and pharmacological studies on brain GABA receptors].
Topics: Animals; Bicuculline; Binding Sites; Brain; gamma-Aminobutyric Acid; Muscimol; Pyridazines; Rats; Receptors, GABA-A; Surface-Active Agents; Up-Regulation | 1994 |
68 other study(ies) available for muscimol and sr 95531
| Article | Year |
|---|---|
Condensation of muscimol or thiomuscimol with aminopyridazines yields GABA-A antagonists.
Topics: Animals; Binding, Competitive; Convulsants; Female; GABA-A Receptor Antagonists; In Vitro Techniques; Mice; Models, Molecular; Molecular Conformation; Muscimol; Pyridazines; Radioligand Assay; Rats; Receptors, GABA-A; Structure-Activity Relationship | 1992 |
A novel class of potent 3-isoxazolol GABA(A) antagonists: design, synthesis, and pharmacology.
Topics: Animals; Brain; Cells, Cultured; GABA Antagonists; Isoxazoles; Models, Molecular; Muscimol; Neurons; Patch-Clamp Techniques; Piperidines; Radioligand Assay; Rats; Receptors, GABA-A; Structure-Activity Relationship; Synaptic Membranes | 2000 |
Age-dependent regulation of GABAA receptors in neocortex.
Topics: Aging; Animals; Baclofen; Cats; Cerebral Cortex; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kinetics; Muscimol; Pyridazines; Rats; Rats, Wistar; Receptors, GABA-A; Veratridine | 1992 |
The GABAA receptor complex in experimental absence seizures in rat: an autoradiographic study.
Topics: Animals; Autoradiography; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Chlorides; Convulsants; Epilepsy, Absence; Flunitrazepam; GABA-A Receptor Antagonists; Ion Channels; Ionophores; Male; Membrane Proteins; Muscimol; Organ Specificity; Pyramidal Tracts; Pyridazines; Rats; Rats, Wistar; Receptors, GABA-A; Sulfur Radioisotopes; Tritium | 1992 |
Characterization of antagonistic activity and binding properties of SR 95531, a pyridazinyl-GABA derivative, in rat brain and cultured cerebellar neuronal cells.
Topics: Animals; Brain; Cells, Cultured; Cerebellum; Cerebral Cortex; Chlorine; GABA Antagonists; Kinetics; Male; Muscimol; Neurons; Pyridazines; Rats; Rats, Inbred Strains; Synaptosomes | 1992 |
A transient osmotic permeabilization method for the introduction of impermeant molecules into functional brain membrane vesicles.
Topics: Alkaline Phosphatase; Animals; Capsules; Carbon Radioisotopes; Cell Membrane; Cell Membrane Permeability; Chloride Channels; Chlorides; Chlorine; Concanavalin A; Flunitrazepam; Hypotonic Solutions; Membrane Proteins; Mice; Mice, Inbred ICR; Muscimol; Pyridazines; Radioisotope Dilution Technique; Radioisotopes; Receptors, Concanavalin A; Receptors, GABA-A; Sucrose; Tritium | 1991 |
Characterization and differential regulation of GABAA and benzodiazepine receptors in rat neocortex.
Topics: Animals; Autoradiography; Binding, Competitive; Brain; Cerebral Cortex; Clonazepam; Down-Regulation; Flunitrazepam; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Kinetics; Male; Muscimol; Pyridazines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Tritium; Veratridine | 1991 |
Presence of a highly efficient "binding" to bacterial contamination can distort data from binding studies.
Topics: Animals; Cats; Cerebral Cortex; GABA Antagonists; gamma-Aminobutyric Acid; Gram-Positive Bacteria; Isonicotinic Acids; Muscimol; Nipecotic Acids; Proline; Pyridazines; Radioligand Assay; Receptors, GABA-A; Tritium | 1990 |
Chronic agonist exposure induces down-regulation and allosteric uncoupling of the gamma-aminobutyric acid/benzodiazepine receptor complex.
Topics: Allosteric Regulation; Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Chick Embryo; Down-Regulation; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Muscimol; Pyridazines; Receptors, GABA-A | 1990 |
Stimulation of luteinizing hormone release by gamma-aminobutyric acid (GABA) agonists: mediation by GABAA-type receptors and activation of chloride and voltage-sensitive calcium channels.
Topics: Amino Acid Sequence; Animals; Baclofen; Calcium Channels; Cells, Cultured; Chloride Channels; Chlorides; Female; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Isoxazoles; Luteinizing Hormone; Membrane Proteins; Molecular Sequence Data; Muscimol; Nifedipine; Pituitary Gland, Anterior; Pyridazines; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1990 |
Dissociation of muscimol, SR 95531, and strychnine from GABAA and glycine receptors, respectively, suggests similar cooperative interactions.
Topics: Animals; Brain; GABA Antagonists; Glycine; Muscimol; Pyridazines; Receptors, GABA-A; Receptors, Glycine; Receptors, Neurotransmitter; Strychnine; Synaptosomes | 1990 |
Phosphorylation-independent effects of second messenger system modulators on gamma-aminobutyric acidA receptor complex function.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Chlorides; Colforsin; Cyclic AMP; Edetic Acid; Isoquinolines; Mice; Mice, Inbred ICR; Muscimol; Phosphorylation; Piperazines; Protein Kinases; Pyridazines; Receptors, GABA-A; Second Messenger Systems | 1990 |
GABAA receptor populations bind agonists and antagonists differentially and with opposite affinities.
Topics: Affinity Labels; Androstanes; Animals; Azasteroids; Brain; Diazepam; Diazonium Compounds; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Photochemistry; Pyridazines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sulfanilic Acids; Synaptic Membranes | 1988 |
Inactivity of phosphoethanolamine, an endogenous GABA analog decreased in Alzheimer's disease, at GABA binding sites.
Topics: Alzheimer Disease; Animals; Ethanolamines; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Pyridazines; Rats; Rats, Inbred F344; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Tritium | 1995 |
Volatile anesthetics bidirectionally and stereospecifically modulate ligand binding to GABA receptors.
Topics: Animals; Cerebral Cortex; Enflurane; Halothane; Isoflurane; Male; Mice; Muscimol; Pyridazines; Radioligand Assay; Receptors, GABA | 1994 |
A novel GABA receptor on bipolar cell terminals in the tiger salamander retina.
Topics: Animals; Bicuculline; Chlorides; Crotonates; Electrophysiology; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Muscimol; Pentobarbital; Picrotoxin; Pyridazines; Receptors, GABA; Receptors, GABA-A; Retina; Retinal Ganglion Cells; Urodela | 1994 |
Subtype specificity of gamma-aminobutyric acid type A receptor antagonism by clozapine.
Topics: Animals; Antipsychotic Agents; Brain; Bridged Bicyclo Compounds, Heterocyclic; Clozapine; GABA Antagonists; GABA-A Receptor Antagonists; Male; Muscimol; Pyridazines; Rats; Rats, Wistar; Receptors, GABA-A | 1995 |
Effects of GABA receptor antagonists injected spinally on antinociception induced by opioids administered supraspinally in mice.
Topics: Amino Acids; Amino Acids, Neutral; Animals; Baclofen; beta-Endorphin; Dose-Response Relationship, Drug; GABA Antagonists; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morphine; Muscimol; Pain Measurement; Pyridazines; Reaction Time; Receptors, Opioid; Receptors, Opioid, mu | 1996 |
Ligand-gated ion channel subunit partnerships: GABAA receptor alpha6 subunit gene inactivation inhibits delta subunit expression.
Topics: Animals; Behavior, Animal; Benzodiazepines; Cerebellum; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; Gene Expression Regulation; Ion Channel Gating; Ion Channels; Lac Operon; Ligands; Male; Mice; Mice, Knockout; Muscimol; Neurons; Protein Processing, Post-Translational; Pyridazines; Receptors, GABA-A; RNA, Messenger | 1997 |
Inhibition of GABAA receptor chloride channel by quinolones and norfloxacin-biphenylacetic acid hybrid compounds.
Topics: Animals; Anti-Infective Agents; Chloride Channels; Chlorine; Enoxacin; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; Male; Muscimol; Norfloxacin; Phenylacetates; Pyridazines; Quinolones; Rats; Rats, Wistar; Synaptosomes | 1996 |
Distribution of GABAA receptors in the limbic system of alcohol-preferring and non-preferring rats: in situ hybridisation histochemistry and receptor autoradiography.
Topics: Alcohol Drinking; Animals; Autoradiography; Cerebral Cortex; Food Preferences; GABA Antagonists; Histocytochemistry; In Situ Hybridization; Limbic System; Male; Muscimol; Pyridazines; Rats; Rats, Inbred WKY; Receptors, GABA; Receptors, GABA-A; RNA, Messenger; Tissue Distribution; Tritium | 1998 |
Central GABAA and GABAB receptor modulation of basal and stress-induced plasma interleukin-6 levels in mice.
Topics: Animals; Baclofen; Brain; Dizocilpine Maleate; GABA Modulators; Injections, Intraventricular; Interleukin-6; Male; Mice; Mice, Inbred ICR; Muscimol; Oxidopamine; Pyridazines; Receptors, GABA-A; Receptors, GABA-B; Stress, Physiological | 1998 |
Defining affinity with the GABAA receptor.
Topics: Animals; Animals, Newborn; beta-Alanine; Cells, Cultured; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Hippocampus; Isoxazoles; Ligands; Muscimol; Neurons; Patch-Clamp Techniques; Pyridazines; Rats; Receptors, GABA-A | 1998 |
Differential potentiative effects of GABA receptor agonists in the production of antinociception induced by morphine and beta-endorphin administered intrathecally in the mouse.
Topics: Amino Acids; Amino Acids, Neutral; Analgesics; Animals; Baclofen; beta-Endorphin; Drug Synergism; GABA Agonists; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Muscimol; Pyridazines; Receptors, GABA-A; Receptors, GABA-B | 2000 |
Entropy as the predominant driving force of binding to human recombinant alpha(x)beta(3)gamma(2) GABA(A) receptors.
Topics: Animals; Binding, Competitive; Dose-Response Relationship, Drug; Entropy; GABA Agonists; GABA Antagonists; Humans; Isoxazoles; L Cells; Membranes; Mice; Muscimol; Piperidines; Pyridazines; Receptors, GABA-A; Recombinant Proteins; Temperature; Tritium | 2001 |
Microscopic kinetics and energetics distinguish GABA(A) receptor agonists from antagonists.
Topics: Animals; Brain; Diffusion; Electrophysiology; Energy Metabolism; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Inhibitory Concentration 50; Isoxazoles; Kinetics; Muscimol; Phosphinic Acids; Protein Binding; Pyridazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2001 |
Molecular and pharmacological characterization of GABA(A) receptor alpha1 subunit knockout mice.
Topics: Animals; Autoradiography; Bicuculline; Blotting, Western; Cerebral Cortex; Chlorides; Convulsants; Female; GABA Agonists; GABA Antagonists; Kinetics; Ligands; Male; Mice; Mice, Knockout; Muscimol; Pyridazines; Radioligand Assay; Receptors, GABA-A; Seizures | 2002 |
Age-related modifications of the morphological organization of pituicytes are associated with alteration of the GABAergic and dopaminergic innervation afferent to the neurohypophysial lobe.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Afferent Pathways; Aging; Animals; Astrocytes; Axons; Cell Count; Dopamine; Dopamine Agonists; Dopamine Antagonists; Drug Interactions; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Hypothalamus; Immunohistochemistry; In Vitro Techniques; Isotonic Solutions; Male; Microscopy, Electron; Microscopy, Immunoelectron; Muscimol; Pyridazines; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, GABA-A; Sulpiride; Tyrosine 3-Monooxygenase | 2003 |
Effects of chronic infusion of a GABAA receptor agonist or antagonist into the vestibular nuclear complex on vestibular compensation in the guinea pig.
Topics: Animals; Dose-Response Relationship, Drug; Guinea Pigs; Male; Muscimol; Nystagmus, Physiologic; Posture; Pyridazines; Receptors, GABA-A; Reflex; Vestibular Nuclei | 2005 |
GABAergic modulation of the activity of globus pallidus neurons in primates: in vivo analysis of the functions of GABA receptors and GABA transporters.
Topics: Action Potentials; Animals; Anisoles; Baclofen; Brain Mapping; Enzyme Inhibitors; GABA Agonists; GABA Antagonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Globus Pallidus; Immunohistochemistry; Macaca mulatta; Membrane Transport Modulators; Membrane Transport Proteins; Microdialysis; Microscopy, Immunoelectron; Muscimol; Neurons; Nipecotic Acids; Phosphinic Acids; Propanolamines; Pyridazines; Receptors, GABA | 2005 |
Feed-forward facilitation of glutamate release by presynaptic GABA(A) receptors.
Topics: Animals; Axons; Electrophysiology; Feedback, Physiological; GABA Agonists; Glutamic Acid; Hippocampus; Male; Muscimol; Nerve Endings; Neural Pathways; Neurons, Afferent; Pyridazines; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Presynaptic; Synaptic Transmission | 2005 |
The neurosteroid 3alphaDIOL modulates place preference when infused in the basolateral amygdala according to sex.
Topics: Amygdala; Analysis of Variance; Animals; Behavior, Animal; Conditioning, Operant; Estradiol; Estrogens; Exploratory Behavior; Female; GABA Agonists; GABA Antagonists; Male; Maze Learning; Motor Activity; Muscimol; Ovariectomy; Pyridazines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Sex Characteristics; Spatial Behavior; Steroids | 2006 |
Origins of GABA(A) and GABA(B) receptor-mediated responses of globus pallidus induced after stimulation of the putamen in the monkey.
Topics: Action Potentials; Animals; Electric Stimulation; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Macaca fascicularis; Macaca mulatta; Muscimol; Neurons; Phosphinic Acids; Propanolamines; Putamen; Pyridazines; Receptors, GABA | 2006 |
Central effects of the anabolic steroid 17alpha methyltestosterone in female anxiety.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Dorsomedial Hypothalamic Nucleus; Female; Interpersonal Relations; Methyltestosterone; Muscimol; Pyridazines; Rats; Rats, Sprague-Dawley; Sex Factors | 2006 |
Regionally selective effects of GABA on hypothalamic GABAA receptor mRNA in vitro.
Topics: Animals; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hypothalamus; Isoenzymes; Male; Muscimol; Nipecotic Acids; Oximes; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; RNA, Messenger; Tetrodotoxin | 2007 |
Early functional development of interneurons in the zebrafish olfactory bulb.
Topics: Animals; Calcium; Drug Interactions; ELAV Proteins; ELAV-Like Protein 3; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation, Developmental; Green Fluorescent Proteins; Homeodomain Proteins; Imaging, Three-Dimensional; Interneurons; Muscimol; Neural Inhibition; Odorants; Olfactory Bulb; Pyridazines; Zebrafish; Zebrafish Proteins | 2007 |
GABAergic interneurons facilitate mossy fiber excitability in the developing hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Axons; Bicuculline; Cyclopropanes; Enkephalin, Methionine; Excitatory Postsynaptic Potentials; Fluorescent Dyes; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glycine; Hippocampus; Interneurons; Male; Mice; Mice, Inbred C57BL; Mossy Fibers, Hippocampal; Muscimol; Patch-Clamp Techniques; Picrotoxin; Presynaptic Terminals; Pyridazines; Pyridinium Compounds; Receptors, GABA-A; Synaptic Transmission; Tetrodotoxin | 2007 |
Allosteric uncoupling and up-regulation of benzodiazepine and GABA recognition sites following chronic diazepam treatment of HEK 293 cells stably transfected with alpha1beta2gamma2S subunits of GABA (A) receptors.
Topics: Allosteric Regulation; Animals; Benzodiazepines; Binding Sites; Binding, Competitive; Cell Line; Diazepam; Flumazenil; Flunitrazepam; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Muscimol; Picrotoxin; Protein Subunits; Pyridazines; Radioligand Assay; Rats; Receptors, GABA-A; Receptors, GABA-B; Transfection; Up-Regulation | 2007 |
Development of chloride-mediated inhibition in neurons of the anteroventral cochlear nucleus of gerbil (Meriones unguiculatus).
Topics: Animals; Brain Stem; Chlorides; Cochlear Nucleus; Electrophysiology; Furosemide; GABA Antagonists; gamma-Aminobutyric Acid; Gerbillinae; Glycine; Muscimol; Neurons; Pyridazines; Receptors, GABA-A; Synaptic Transmission | 2007 |
Prostaglandin E(2) fever mediated by inhibition of the GABAergic transmission in the region immediately adjacent to the organum vasculosum of the lamina terminalis.
Topics: Animals; Bicuculline; Body Temperature; Dinoprostone; Dose-Response Relationship, Drug; Fever; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; Hypothalamus; Male; Muscimol; Preoptic Area; Pyridazines; Rats; Rats, Wistar; Synaptic Transmission; Vasoconstriction | 2008 |
Effects of striatal GABA A-receptor blockade on striatal and cortical activity in monkeys.
Topics: Action Potentials; Animals; Corpus Striatum; Dose-Response Relationship, Drug; Electroencephalography; Evoked Potentials; Female; GABA Agonists; GABA Antagonists; Macaca mulatta; Microdialysis; Motor Cortex; Muscimol; Neurons; Pyridazines; Receptors, GABA-A | 2008 |
GABA actions in hippocampal area CA3 during postnatal development: differential shift from depolarizing to hyperpolarizing in somatic and dendritic compartments.
Topics: Age Factors; Animals; Animals, Newborn; Dendrites; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Membrane Potentials; Muscimol; Neural Inhibition; Neurons; Patch-Clamp Techniques; Pyridazines; Quinoxalines; Rats; Rats, Wistar; Valine | 2008 |
Individually monitoring ligand-induced changes in the structure of the GABAA receptor at benzodiazepine binding site and non-binding-site interfaces.
Topics: Animals; Benzodiazepines; Binding Sites; Cysteine; Dose-Response Relationship, Drug; Electrophysiology; Female; Flumazenil; Flurazepam; GABA Agonists; GABA Antagonists; GABA Modulators; Inhibitory Concentration 50; Ligands; Microinjections; Muscimol; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Pentobarbital; Pyridazines; Rats; Receptors, GABA-A; Xenopus | 2008 |
Inflammation-induced shift in the valence of spinal GABA-A receptor-mediated modulation of nociception in the adult rat.
Topics: Animals; Antineoplastic Agents; Flumazenil; Freund's Adjuvant; GABA Agonists; GABA Antagonists; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Hyperalgesia; Inflammation; Injections, Spinal; Isoquinolines; Male; Midazolam; Muscimol; Nociceptors; Pain Measurement; Pain Threshold; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Signal Transduction; Spinal Cord | 2008 |
Dissociation constants for GABA(A) receptor antagonists determined with neuronal networks on microelectrode arrays.
Topics: Action Potentials; Animals; Bicuculline; Cell Culture Techniques; Cells, Cultured; Dose-Response Relationship, Drug; Electrophysiology; Frontal Lobe; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; Mice; Mice, Inbred ICR; Microelectrodes; Muscimol; Nerve Net; Neurons; Propylene Glycols; Pyridazines; Receptors, GABA-A; Tissue Array Analysis | 2008 |
Diencephalic locomotor region in the lamprey--afferents and efferent control.
Topics: Animals; Behavior, Animal; Biotin; Brain Mapping; Diencephalon; Dose-Response Relationship, Radiation; Electric Stimulation; Electromyography; Functional Laterality; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Lampreys; Locomotion; Muscimol; Neural Pathways; Pyridazines | 2008 |
D1-like dopamine receptors regulate GABAA receptor function to modulate hippocampal neural progenitor cell proliferation.
Topics: Animals; Animals, Newborn; Bromodeoxyuridine; Calcium; Calcium Channel Blockers; Cell Count; Cell Proliferation; Cells, Cultured; Dopamine Agents; Drug Interactions; Enzyme-Linked Immunosorbent Assay; GABA Agents; Gene Expression; Hippocampus; Mice; Muscimol; Neurons; Nifedipine; Pyridazines; Receptors, Dopamine D1; Receptors, GABA-A; Stem Cells | 2008 |
Modulation of the sympathetic response to acute hypoxia by the caudal ventrolateral medulla in rats.
Topics: Animals; Bicuculline; Blood Pressure; Excitatory Amino Acid Antagonists; GABA Agonists; GABA-A Receptor Antagonists; Glutamic Acid; Hypoxia; Kynurenic Acid; Male; Medulla Oblongata; Models, Neurological; Muscimol; Neurons; Phrenic Nerve; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Respiratory Mechanics; Sodium Cyanide; Splanchnic Nerves; Strychnine; Sympathetic Nervous System; Vagotomy | 2009 |
The GABAA agonist muscimol attenuates induced airway constriction in guinea pigs in vivo.
Topics: Acetylcholine; Airway Obstruction; Animals; Autonomic Nervous System; Capsaicin; Constriction, Pathologic; Electric Stimulation; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; Guanethidine; Guinea Pigs; Histamine; Male; Muscimol; Muscle, Smooth; Parasympathetic Nervous System; Pyridazines; Sympathetic Fibers, Postganglionic; Sympatholytics; Vagus Nerve | 2009 |
Endogenous gamma-aminobutyric acid modulates tonic guinea pig airway tone and propofol-induced airway smooth muscle relaxation.
Topics: Acetylcholine; Anesthetics, Intravenous; Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Immunohistochemistry; Male; Models, Animal; Muscimol; Muscle Relaxation; Muscle, Smooth; Propofol; Pyridazines; Random Allocation; Substance P; Trachea | 2009 |
GABA(A) and GABA(B) receptors of distinct properties affect oppositely the proliferation of mouse embryonic stem cells through synergistic elevation of intracellular Ca(2+).
Topics: Animals; Baclofen; Calcium; Calcium Channels; Cell Differentiation; Cell Movement; Cell Proliferation; Embryonic Stem Cells; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Gene Expression Regulation; Mice; Muscimol; Pluripotent Stem Cells; Pyridazines; Receptors, GABA-A; Receptors, GABA-B; Time Factors | 2010 |
Respiratory responses induced by blockades of GABA and glycine receptors within the Bötzinger complex and the pre-Bötzinger complex of the rabbit.
Topics: Animals; Bicuculline; GABA Antagonists; GABA-A Receptor Agonists; Glycine Agents; Hypercapnia; Male; Microinjections; Muscimol; Organophosphorus Compounds; Pyridazines; Rabbits; Receptors, GABA; Receptors, Glycine; Respiratory Center; Respiratory Physiological Phenomena; Strychnine; Time Factors | 2010 |
Disruption of the olivo-cerebellar circuit by Purkinje neuron-specific ablation of BK channels.
Topics: Action Potentials; Animals; Brain; Cerebellar Nuclei; Cerebellum; Immunohistochemistry; Large-Conductance Calcium-Activated Potassium Channels; Mice; Mice, Knockout; Motor Activity; Muscimol; Organic Chemicals; Patch-Clamp Techniques; Purkinje Cells; Pyridazines | 2010 |
Spinal cord mechanisms mediating behavioral hyperalgesia induced by neurokinin-1 tachykinin receptor activation in the rostral ventromedial medulla.
Topics: Animals; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Excitatory Amino Acid Antagonists; Freund's Adjuvant; GABA Agents; Hyperalgesia; In Vitro Techniques; Inflammation; Male; Medulla Oblongata; Membrane Potentials; Microinjections; Muscimol; Ondansetron; Oxazines; Pain Measurement; Pain Threshold; Posterior Horn Cells; Pyridazines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Neurokinin-1; Serotonin Antagonists; Spinal Cord; Substance P; Tryptophan; Up-Regulation | 2010 |
Inhibitory plasticity underlies visual deprivation-induced loss of receptive field refinement in the adult superior colliculus.
Topics: Animals; Cricetinae; Electrophysiology; GABA Antagonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Mesocricetus; Muscimol; Neuronal Plasticity; Photic Stimulation; Pyridazines; Receptors, GABA-A; Sensory Deprivation; Superior Colliculi; Visual Cortex; Visual Fields; Visual Pathways; Visual Perception | 2011 |
Development of asymmetric inhibition underlying direction selectivity in the retina.
Topics: Action Potentials; Amacrine Cells; Animals; Dendrites; Electric Conductivity; gamma-Aminobutyric Acid; Mice; Mice, Transgenic; Models, Neurological; Motion; Motion Perception; Muscimol; Neural Inhibition; Neuronal Plasticity; Patch-Clamp Techniques; Photic Stimulation; Pyridazines; Retina; Retinal Ganglion Cells; Synapses | 2011 |
Biphasic action of axonal GABA-A receptors on presynaptic calcium influx.
Topics: Animals; Animals, Newborn; Axons; Calcium; Cerebellum; Electric Stimulation; Extracellular Fluid; GABA Antagonists; GABA-A Receptor Agonists; Glycine; In Vitro Techniques; Muscimol; Neurons; Presynaptic Terminals; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Xanthenes | 2011 |
Paraventricular hypothalamic regulation of trigeminovascular mechanisms involved in headaches.
Topics: Action Potentials; Animals; Biotin; Corticosterone; Dextrans; Disease Models, Animal; GABA Antagonists; GABA-A Receptor Agonists; Male; Muscimol; Neural Pathways; Neurons; Paraventricular Hypothalamic Nucleus; Physical Stimulation; Piperidines; Pituitary Adenylate Cyclase-Activating Polypeptide; Pyridazines; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Stilbamidines; Stress, Psychological; Trigeminal Nuclei; Tryptamines | 2013 |
GABA(A) receptor agonist and antagonist alter vestibular compensation and different steps of reactive neurogenesis in deafferented vestibular nuclei of adult cats.
Topics: Animals; Astrocytes; Cats; Cell Proliferation; Denervation; Eye Movements; GABA Agonists; GABA Antagonists; GABAergic Neurons; Male; Muscimol; Neurogenesis; Postural Balance; Pyridazines; Vestibular Nerve; Vestibular Nuclei | 2013 |
CO2-induced ocean acidification increases anxiety in rockfish via alteration of GABAA receptor functioning.
Topics: Animals; Anxiety; Behavior, Animal; Carbon Dioxide; Environmental Exposure; Fish Proteins; GABA Antagonists; GABA-A Receptor Agonists; Hydrogen-Ion Concentration; Muscimol; Oceans and Seas; Perciformes; Pyridazines; Receptors, GABA-A; Seawater | 2014 |
Benzodiazepine-dependent stabilization of GABA(A) receptors at synapses.
Topics: Animals; Carrier Proteins; Cells, Cultured; Diazepam; GABA Agonists; GABA Antagonists; GABA Modulators; Membrane Proteins; Mice; Muscimol; Protein Binding; Protein Subunits; Protein Transport; Pyridazines; Receptors, GABA-A; Synapses; Synaptic Potentials | 2014 |
The lateral septum as a regulator of hippocampal theta oscillations and defensive behavior in rats.
Topics: Animals; Anxiety; Defense Mechanisms; GABA Agonists; GABA Antagonists; Hippocampus; Male; Muscimol; Pyridazines; Rats; Rats, Long-Evans; Septal Nuclei; Theta Rhythm | 2015 |
GABA and glycine receptors in the nucleus ambiguus mediate tachycardia elicited by chemical stimulation of the hypothalamic arcuate nucleus.
Topics: Animals; Arcuate Nucleus of Hypothalamus; GABA Antagonists; GABA-A Receptor Agonists; Glycine Agents; Heart; Male; Medulla Oblongata; Microinjections; Muscimol; N-Methylaspartate; Pyridazines; Rats, Wistar; Receptors, GABA-A; Receptors, Glycine; Stimulation, Chemical; Strychnine; Tachycardia | 2015 |
Transient, activity dependent inhibition of transmitter release from low threshold afferents mediated by GABAA receptors in spinal cord lamina III/IV.
Topics: Action Potentials; Animals; Excitatory Postsynaptic Potentials; Female; Male; Models, Neurological; Muscimol; Neurons, Afferent; Neurotransmitter Agents; Pyridazines; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Glycine; Sensory Thresholds; Spinal Cord Dorsal Horn; Synapses | 2015 |
Chronic Unpredictable Mild Stress Induces Loss of GABA Inhibition in Corticotrophin-Releasing Hormone-Expressing Neurons through NKCC1 Upregulation.
Topics: Animals; Bumetanide; Corticosterone; Corticotropin-Releasing Hormone; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Membrane Potentials; Muscimol; Neural Inhibition; Neurons; Paraventricular Hypothalamic Nucleus; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sodium Potassium Chloride Symporter Inhibitors; Solute Carrier Family 12, Member 2; Stress, Psychological; Up-Regulation | 2017 |
GABA is an inhibitory neurotransmitter in the neural circuit regulating metamorphosis in a marine snail.
Topics: Aminooxyacetic Acid; Animals; Anions; Bicuculline; Chlorides; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Larva; Metamorphosis, Biological; Muscimol; Neurotransmitter Agents; Pyridazines; Receptors, GABA-A; Serotonin; Snails | 2018 |
Place cell firing cannot support navigation without intact septal circuits.
Topics: Action Potentials; Anesthetics, Local; Animals; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Hippocampus; Male; Muscimol; Place Cells; Pyridazines; Rats; Rats, Long-Evans; Septum of Brain; Spatial Navigation; Tetracaine | 2020 |
Propofol Causes Consciousness Loss by Affecting GABA-A Receptor in the Nucleus Basalis of Rats.
Topics: Animals; Basal Nucleus of Meynert; Consciousness; Electroencephalography; Male; Muscimol; Propofol; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2020 |