muscimol and isoxazoles

muscimol has been researched along with isoxazoles in 133 studies

Research

Studies (133)

Timeframe	Studies, this research(%)	All Research%
pre-1990	77 (57.89)	18.7374
1990's	27 (20.30)	18.2507
2000's	19 (14.29)	29.6817
2010's	9 (6.77)	24.3611
2020's	1 (0.75)	2.80

Authors

Authors	Studies
Arnt, J; Krogsgaard-Larsen, P	1
Polc, P	1
Braestrup, C; Falch, E; Krogsgaard-Larsen, P; Nielsen, M	1
Karobath, M; Lippitsch, M	1
Andrews, PR; Johnston, GA	1
Curtis, DR; Johnston, GA; Lodge, D	1
Arnt, J; Scheel-Krüger, J	1
Aprison, MH; Lipkowitz, KB	1
Ebbesson, SO; Erdö, SL; Hofmann, MH; Malz, CR; Meyer, DL	1
Karasawa, T; Mimaki, T; Suzuki, Y; Tagawa, T; Yabuuchi, H	1
Bapna, JS; Ramaswamy, S; Srinivasan, D	1
Fromm, GH; Mukawa, J; Nakata, M	1
Bapna, JS; Rajaram, S; Ramaswamy, S	1
Corbett, R; Cornfeldt, M; Dunn, RW; Fielding, S	1
Boelen, MK; Chubb, IW; Dowton, M; Morgan, IG; Wellard, J	1
Hablitz, JJ; Mistry, DK	1
Bapna, JS; Ramaswamy, S; Srinivasan, B; Srinivasan, D	1
Catt, KJ; Stojilković, SS; Virmani, MA	1
Michler, A	1
Hicks, TP; Kaneko, T	1
Allan, AM; Gallaher, EJ; Gionet, SE; Harris, RA	1
Amenta, F; Erdö, SL; Mione, MC; Wolff, JR	1
Depaulis, A; Marescaux, C; Snead, OC; Vergnes, M	1
Karlsson, G; Olpe, HR	1
Andre, JM; Boulanger, T; Durant, F; Vercauteren, DP	1
Beani, L; Bianchi, C; Tanganelli, S	1
Bond, A; Neal, H	2
Hansen, SH; Krogsgaard-Larsen, P; Nielsen, EO; Schousboe, A	1
Meldrum, BS	1
Alho, H; Fujimoto, M; Geffard, M; Guidotti, A; Hanbauer, I; Kataoka, Y; Kelly, GD	1
Karobath, M; Supavilai, P	2
Iversen, LL; Wong, EH	1
Chweh, AY; Kupferberg, HJ; Swinyard, EA; Wolf, HH	1
Löscher, W; Schwark, WS	1
Gähwiler, BH; Graff, P; Maurer, R; Nordmann, R	1
Curtis, DR; Falch, E; Krogsgaard-Larsen, P; Nielsen, L	1
Allan, AM; Harris, RA	1
Ciesielski, L; Gobaille, S; Mandel, P; Molina, V	1
Falch, E; Hjeds, H; Krogsgaard-Larsen, P	1
Apud, JA; Masotto, C; Racagni, G	1
Lindgren, S	1
DaSilva, AM; Gatti, PJ; Gillis, RA	1
Chapman, AG	1
Borsini, F; Evangelista, S; Meli, A	1
Itoh, Y; Nishibori, M; Oishi, R; Saeki, K	1
Ford, I; Kelly, PA; McCulloch, J	1
Sawynok, J	1
Ben-Ari, Y; Cherubini, E; Rovira, C	1
Meldrum, B	1
Cynader, M; Needler, MC; Shaw, C	1
Maggi, A; Perez, J	1
Bauer, B	1
Forchetti, MC; Guidotti, A; Krogsgaard-Larsen, P; Moroni, F	1
Drejer, J; Meier, E; Schousboe, A	1
Krogsgaard-Larsen, P	1
Kelly, PA; McCulloch, J	2
Brehm, L; Krogsgaard-Larsen, P; Schaumburg, K	1
Cavagnini, F; Grandison, L; Guidotti, A; Invitti, SC; Schmid, R	1
Wood, PL	1
Curtis, DR; Hjeds, H; Krogsgaard-Larsen, P; Leah, JD; Peet, MJ	1
Dutton, GR; Freedman, EG; Pearce, BR	1
Breese, GR; Frye, GD	1
Breese, GR; Frye, GD; McCown, TJ	1
Madtes, P; Redburn, DA	1
Johnston, GA; Skerritt, JH	1
Curtis, DR; Falch, E; Krogsgaard-Larsen, P; Leah, JD; Peet, MJ	1
Deisz, RA; Dose, M	1
Maksay, G; Ticku, MK	1
Bloch, R; Bousquet, P; Feldman, J; Schwartz, J	1
Bjørndal, N; Casey, DE; Christensson, E; Gerlach, J	1
Hare, TA; Tamminga, CA; Thaker, GK	1
Depaulis, A; Marescaux, C; Micheletti, G; Rumbach, L; Vergnes, M; Warter, JM	1
Baumeister, AA; Frye, GD	1
Drower, EJ; Hammond, DL	1
Di Scala, G; Karli, P; Schmitt, P	1
Coward, DM	1
Magelund, G; Olianas, MC; Scheel-Krüger, J	1
Cagiano, R; Cuomo, V; Mocchetti, I; Racagni, G	1
Buescher, HH; Hill, RC; Maurer, R; Roemer, D	1
Kuhar, MJ; London, ED; Palacios, JM; Rapoport, SI	1
Magelund, G; Scheel-Krüger, J	1
Ashton, D; Geerts, R; Leysen, JE; Waterkeyn, C	1
Menon, MK	1
Bergstrom, DA; Walters, JR; Waszczak, BL	1
Clark, WG; Menon, MK; Vivonia, C	1
Hruska, RE; Walters, JR; Waszczak, BL	1
Walters, JR; Waszczak, BL	1
Delorey, TM; Endo, S; Huh, KH; Olsen, RW	1
Garant, DS; Moshé, SL; Sperber, EF; Xu, SG	1
Aprison, MH; Galvez-Ruano, E; Lipkowitz, KB	1
Ebert, B; Kemp, JA; Krogsgaard-Larsen, P; Wafford, KA; Whiting, PJ	1
Kim, HY; Olsen, RW; Sapp, DW; Tobin, AJ	1
Barker, JL; Behar, T; Fiszman, ML; Lange, GD; Novotny, EA; Smith, SV	1
Matsutani, S; Yamamoto, N	1
Ebert, B; Krogsgaard-Larsen, P; McKernan, R; Saounatsou, K; Thompson, SA; Wafford, KA	1
Nicklas, WJ; Zeevalk, GD	1
Geter-Douglass, B; Tirelli, E; Witkin, JM	1
Aleo, MD; Miller, GW; Schnellmann, RG; Waters, SL	1
Kulinskiĭ, VI; Mikhel'son, GV	2
Dzubay, JA; Jones, MV; Sahara, Y; Westbrook, GL	1
González, MP; Herrero, MT; López, E; Oset-Gasque, MJ; Vicente, S	1
Falch, E; Krogsgaard-Larsen, P; Sørensen, US	1
Maksay, G; McKernan, R	1
Engblom, C; Frølund, B; Kristiansen, U; Krogsgaard-Larsen, P; Liljefors, T; Stensbøl, TB; Tagmose, L	1
Jonas, P; Jones, MV; Sahara, Y; Westbrook, GL	1
Ebert, B; Frølund, B; Kristiansen, U; Krogsgaard-Larsen, P; Liljefors, T	1
Johnston, GA	1
Brünig, I; Fritschy, JM; Studler, B	1
Kristensen, BW; Noraberg, J; Zimmer, J	1
Frosini, M; Sgaragli, G; Valoti, M	1
Barry, PH; Carland, JE; Chebib, M; Johnston, GA; Moorhouse, AJ	1
Bjerrum, OJ; Blackburn-Munro, G; Jensen, DG; Rode, F	1
Jia, H; Qu, CL; Tang, JS	1
Gartside, SE; Ingram, CD; Judge, SJ; Kaura, V; Young, AH	1
Blednov, YA; Boehm, SL; Harris, RA; Homanics, GE	1
Boehm, SL; Goldfarb, KJ; Linsenbardt, DN; Moore, EM; Serio, KM; Stepanovska, S	1
Frølund, B; Larsen, BB; Larsen, M; Nielsen, CU	1
Akabas, MH; Dannhardt, G; Debus, F; Dieler, S; Jansen, M; Lüddens, H; Rabe, H; Strehle, A	1
Ehlen, JC; Paul, KN	1
Ebert, B; Mortensen, M; Smart, TG; Wafford, K	1
Leopold, DA; Mishkin, M; Smith, K; Turchi, J; Wilke, M	1
Asiedu, MN; Kaila, K; Malan, TP; Mejia, G; Ossipov, MK; Price, TJ	1
Baghdoyan, HA; Vanini, G	1
Boychuk, CR; Halmos, KC; Smith, BN	1
Furuta, K; Liu, G; Ozoe, F; Ozoe, Y	1
Boehm, SL; Quoilin, C	1
Johnston, GAR	1
Cai, J; Chen, RX; Liao, FF; Liu, FY; Wan, Y; Wang, J; Xu, FQ; Yi, M; Zhang, C; Zhang, Y	1
Cruces, W; Docampo-Palacios, ML; Okhovat, A; Ramirez, GA; Ray, KP	1

Reviews

12 review(s) available for muscimol and isoxazoles

Article	Year
Drugs acting on amino acid neurotransmitters. Advances in neurology, 1986, Volume: 43 Topics: Acoustic Stimulation; Amino Acids; Animals; Chemical Phenomena; Chemistry; Diazepam; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Humans; Hypoxia; Imidazoles; Isoxazoles; Mice; Mice, Inbred DBA; Muscimol; Myoclonus; Neurotransmitter Agents; Papio; Rats; Rats, Inbred Strains; Seizures; Valproic Acid	1986
Heterocyclic analogues of GABA: chemistry, molecular pharmacology and therapeutic aspects. Progress in medicinal chemistry, 1985, Volume: 22 Topics: Analgesics; Animals; Anticonvulsants; Blood-Brain Barrier; Chemical Phenomena; Chemistry; gamma-Aminobutyric Acid; Humans; Isoxazoles; Muscimol; Nipecotic Acids; Receptors, GABA-A	1985
Valproate and myoclonus. Advances in neurology, 1986, Volume: 43 Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Aspartic Acid; Clonazepam; DDT; Disease Models, Animal; Flurazepam; gamma-Aminobutyric Acid; Glycine; Isoxazoles; Light; Morphine; Muscimol; Myoclonus; Serotonin; Urea; Valproic Acid	1986
Inhibitors of the GABA uptake systems. Molecular and cellular biochemistry, 1980, Jun-18, Volume: 31, Issue:2 Topics: Animals; Astrocytes; Biological Transport; Brain; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Isoxazoles; Muscimol; Neuroglia; Neurons; Nipecotic Acids; Receptors, Neurotransmitter; Structure-Activity Relationship; Synapses; Synaptosomes	1980
Muscimol, a psychoactive constituent of Amanita muscaria, as a medicinal chemical model structure. Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry, 1981, Volume: 35, Issue:5 Topics: Agaricales; Amanita; Animals; gamma-Aminobutyric Acid; Isonicotinic Acids; Isoxazoles; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Structural; Molecular Conformation; Muscimol; Nipecotic Acids; Oxazoles; Receptors, Cell Surface; Receptors, GABA-A; Stereoisomerism	1981
Molecular pharmacology of the GABA receptors and GABA agonists. Advances in biochemical psychopharmacology, 1983, Volume: 37 Topics: Animals; Bicuculline; gamma-Aminobutyric Acid; Humans; Isoxazoles; Molecular Conformation; Muscimol; Neurons; Receptors, Cell Surface; Receptors, GABA-A; Stereoisomerism; Synapses	1983
GABA system: clinical research and treatment of tardive dyskinesia. Modern problems of pharmacopsychiatry, 1983, Volume: 21 Topics: Alkynes; Aminocaproates; Benzodiazepines; Clinical Trials as Topic; Corpus Striatum; Dopamine; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Humans; Isoxazoles; Muscimol; Substantia Nigra; Valproic Acid; Vigabatrin	1983
Role of GABA in the striatal output system: globus pallidus, nucleus entopeduncularis, substantia nigra and nucleus subthalamicus. Advances in biochemical psychopharmacology, 1981, Volume: 30 Topics: Animals; Basal Ganglia; Behavior, Animal; Corpus Striatum; Dopamine; Functional Laterality; gamma-Aminobutyric Acid; Globus Pallidus; Isoxazoles; Male; Muscimol; Rats; Rats, Inbred Strains; Substantia Nigra; Thalamus	1981
GABA(A) receptor ligands and their therapeutic potentials. Current topics in medicinal chemistry, 2002, Volume: 2, Issue:8 Topics: Animals; Central Nervous System Diseases; GABA Agents; GABA Agonists; GABA Antagonists; Humans; Isonicotinic Acids; Isoxazoles; Ligands; Muscimol; Piperidines; Protein Subunits; Receptors, GABA-A	2002
Medicinal chemistry and molecular pharmacology of GABA(C) receptors. Current topics in medicinal chemistry, 2002, Volume: 2, Issue:8 Topics: Amino Acids, Cyclic; Animals; Barbiturates; Crotonates; GABA Agonists; GABA Antagonists; Imidazoles; Isoxazoles; Muscimol; Organophosphorus Compounds; Phosphinic Acids; Pyridines; Receptors, GABA; Receptors, GABA-A	2002
GABA Australis, some reflections on the history of GABA receptor research in Australia. Pharmacological research, 2017, Volume: 116 Topics: Animals; Australia; Baclofen; Bicuculline; Cyclic AMP; Humans; Isoxazoles; Muscimol; Receptors, GABA	2017
Psychoactive Isoxazoles, Muscimol, and Isoxazole Derivatives from the Amanita (Agaricomycetes) Species: Review of New Trends in Synthesis, Dosage, and Biological Properties. International journal of medicinal mushrooms, 2023, Volume: 25, Issue:9 Topics: Amanita; GABA Agonists; gamma-Aminobutyric Acid; Isoxazoles; Muscimol	2023

Trials

1 trial(s) available for muscimol and isoxazoles

Article	Year
GABA system: clinical research and treatment of tardive dyskinesia. Modern problems of pharmacopsychiatry, 1983, Volume: 21 Topics: Alkynes; Aminocaproates; Benzodiazepines; Clinical Trials as Topic; Corpus Striatum; Dopamine; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Humans; Isoxazoles; Muscimol; Substantia Nigra; Valproic Acid; Vigabatrin	1983

Other Studies

121 other study(ies) available for muscimol and isoxazoles

Article	Year
GABA agonists and potential antagonists related to muscimol. Brain research, 1979, Nov-16, Volume: 177, Issue:2 Topics: Animals; Dose-Response Relationship, Drug; Functional Laterality; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Isoxazoles; Male; Muscimol; Oxazoles; Rats; Receptors, Neurotransmitter; Stereotyped Behavior; Substantia Nigra	1979
Effects of GABA-mimetic agents on the cat spinal cord. Progress in neuro-psychopharmacology, 1979, Volume: 3, Issue:4 Topics: Animals; Bicuculline; Cats; Drug Interactions; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Spinal; Ibotenic Acid; Isonicotinic Acids; Isoxazoles; Male; Muscimol; Neurons, Afferent; Spinal Cord	1979
Partial agonists for brain GABA/benzodiazepine receptor complex. Nature, 1979, Jul-26, Volume: 280, Issue:5720 Topics: Animals; Benzodiazepines; Bicuculline; Brain; Crotonates; Diazepam; GABA Antagonists; gamma-Aminobutyric Acid; Imidazoles; Isoxazoles; Muscimol; Piperidines; Rats; Receptors, Drug; Sulfonic Acids	1979
THIP and isoguvacine are partial agonists of GABA-stimulated benzodiazepine receptor binding. European journal of pharmacology, 1979, Oct-15, Volume: 58, Issue:4 Topics: Animals; Benzodiazepines; Cerebral Cortex; Drug Synergism; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Isonicotinic Acids; Isoxazoles; Muscimol; Oxazoles; Rats; Receptors, Drug	1979
Conformational analysis of muscimol, a GABA agonist. Journal of theoretical biology, 1979, Aug-07, Volume: 79, Issue:3 Topics: Bicuculline; Binding Sites; gamma-Aminobutyric Acid; Isoxazoles; Models, Molecular; Molecular Conformation; Muscimol; Oxazoles; Quantum Theory	1979
Does uptake limit the actions of GABA agonists in vivo? Experiments with muscimol, isoguvacine and THIP in cat spinal cord. Journal of neurochemistry, 1978, Volume: 31, Issue:6 Topics: Aminobutyrates; Animals; Biological Transport; Cats; gamma-Aminobutyric Acid; Isonicotinic Acids; Isoxazoles; Muscimol; Neurons; Nipecotic Acids; Oxazoles; Spinal Cord	1978
GABA in the ventral tegmental area: differential regional effects on locomotion, aggression and food intake after microinjection of GABA agonists and antagonists. Life sciences, 1979, Oct-08, Volume: 25, Issue:15 Topics: Aggression; Animals; Apomorphine; Behavior, Animal; Bicuculline; Carbachol; Cerebral Cortex; Dopamine; Feeding Behavior; gamma-Aminobutyric Acid; Haloperidol; Humans; Isoxazoles; Male; Methyltyrosines; Morphine; Motor Activity; Muscimol; Picrotoxin; Rats; Reserpine	1979
Muscimol and N,N-dimethylmuscimol: from a GABA agonist to a glycine antagonist. Journal of neuroscience research, 1992, Volume: 31, Issue:1 Topics: Chemical Phenomena; Chemistry, Physical; Computer Simulation; gamma-Aminobutyric Acid; Glycine; Isoxazoles; Models, Molecular; Molecular Structure; Muscimol; Receptors, GABA-A; Receptors, Glycine; Receptors, Neurotransmitter; Structure-Activity Relationship	1992
Changes in ligand binding to GABAA receptor sites in pacific salmon (Oncorhynchus) brain during spawning migration and "aging". Journal fur Hirnforschung, 1992, Volume: 33, Issue:4-5 Topics: Aging; Aminobutyrates; Analgesics; Animals; Baclofen; Bicuculline; Binding, Competitive; Brain; Female; gamma-Aminobutyric Acid; Isoxazoles; Kinetics; Ligands; Male; Muscimol; Receptors, GABA-A; Salmon; Sexual Behavior, Animal	1992
Interaction of zonisamide with benzodiazepine and GABA receptors in rat brain. Medical journal of Osaka University, 1990, Volume: 39, Issue:1-4 Topics: Animals; Anticonvulsants; Brain; Dose-Response Relationship, Drug; Flunitrazepam; Isoxazoles; Male; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, GABA-A; Synaptic Membranes; Zonisamide	1990
Inhibition of tetrahydroisoxazolo-pyridin-3-ol and muscimol and its mechanism on gastrointestinal transit in mice. European journal of pharmacology, 1992, Sep-22, Volume: 220, Issue:2-3 Topics: Animals; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; Gastrointestinal Transit; Isoxazoles; Male; Mice; Muscimol; Phentolamine; Propranolol; Yohimbine	1992
Why are most GABA agonists not effective antiepileptic drugs? The Japanese journal of psychiatry and neurology, 1991, Volume: 45, Issue:2 Topics: Animals; Anticonvulsants; Bicuculline; Cats; Electroencephalography; GABA Antagonists; gamma-Aminobutyric Acid; Isoxazoles; Muscimol; Receptors, GABA-A; Synaptic Transmission; Trigeminal Nucleus, Spinal	1991
Role of calcium in the analgesic action of tetrahydroisoxazolepyridinol and muscimol. The Journal of pharmacy and pharmacology, 1991, Volume: 43, Issue:6 Topics: Analgesics; Animals; Calcium; Calcium Chloride; Isoxazoles; Male; Mice; Morphine; Muscimol; Nifedipine	1991
GABAmimetic agents display anxiolytic-like effects in the social interaction and elevated plus maze procedures. Psychopharmacology, 1991, Volume: 104, Issue:3 Topics: Aminooxyacetic Acid; Animals; Anti-Anxiety Agents; Conflict, Psychological; Diazepam; Exploratory Behavior; gamma-Aminobutyric Acid; Isonicotinic Acids; Isoxazoles; Male; Muscimol; Rats; Rats, Inbred Strains; Social Behavior; Valproic Acid	1991
Glycinergic control of [Leu5]enkephalin levels in chicken retina. Brain research, 1991, Aug-23, Volume: 557, Issue:1-2 Topics: Animals; Baclofen; Chickens; Enkephalin, Leucine; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Isoxazoles; Muscimol; Neurotransmitter Agents; Picrotoxin; Radioimmunoassay; Retina; Strychnine	1991
Activation of subconductance states by gamma-aminobutyric acid and its analogs in chick cerebral neurons. Pflugers Archiv : European journal of physiology, 1990, Volume: 416, Issue:4 Topics: Analgesics; Animals; Cells, Cultured; Cerebral Cortex; Chick Embryo; Chlorides; Electric Conductivity; gamma-Aminobutyric Acid; Ion Channel Gating; Ion Channels; Isonicotinic Acids; Isoxazoles; Muscimol; Neurons	1990
Tolerance pattern to GABAmimetic analgesics and their influence on morphine tolerance and dependence. Fundamental & clinical pharmacology, 1991, Volume: 5, Issue:9 Topics: Analgesics; Animals; Drug Interactions; Drug Tolerance; Isoxazoles; Male; Mice; Morphine; Muscimol; Naloxone; Substance-Related Disorders	1991
Stimulation of luteinizing hormone release by gamma-aminobutyric acid (GABA) agonists: mediation by GABAA-type receptors and activation of chloride and voltage-sensitive calcium channels. Endocrinology, 1990, Volume: 126, Issue:5 Topics: Amino Acid Sequence; Animals; Baclofen; Calcium Channels; Cells, Cultured; Chloride Channels; Chlorides; Female; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Isoxazoles; Luteinizing Hormone; Membrane Proteins; Molecular Sequence Data; Muscimol; Nifedipine; Pituitary Gland, Anterior; Pyridazines; Rats; Rats, Inbred Strains; Receptors, GABA-A	1990
Involvement of GABA receptors in the regulation of neurite growth in cultured embryonic chick tectum. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 1990, Volume: 8, Issue:4 Topics: Animals; Axons; Baclofen; Cells, Cultured; Chick Embryo; Culture Media; gamma-Aminobutyric Acid; Isoxazoles; Ligands; Muscimol; Receptors, GABA-A; Superior Colliculi	1990
GABA(B)-related activity involved in synaptic processing of somatosensory information in S1 cortex of the anaesthetized cat. British journal of pharmacology, 1990, Volume: 100, Issue:4 Topics: Anesthesia; Animals; Baclofen; Bicuculline; Cats; Electric Stimulation; Electrodes; Female; gamma-Aminobutyric Acid; Iontophoresis; Isoxazoles; Male; Muscimol; Neurons; Physical Stimulation; Somatosensory Cortex; Synapses	1990
Genetic selection for benzodiazepine ataxia produces functional changes in the gamma-aminobutyric acid receptor chloride channel complex. Brain research, 1988, Jun-14, Volume: 452, Issue:1-2 Topics: Animals; Ataxia; Chlorides; Diazepam; Ethanol; Flunitrazepam; Ion Channels; Isoxazoles; Mice; Muscimol; Phenobarbital; Receptors, GABA-A; Time Factors	1988
Binding of [3H]-muscimol to GABAA sites in the guinea-pig urinary bladder: biochemical assay and autoradiography. British journal of pharmacology, 1989, Volume: 96, Issue:2 Topics: Animals; Autoradiography; Bicuculline; Binding, Competitive; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Isoxazoles; Muscimol; Receptors, GABA-A; Tritium; Urinary Bladder	1989
Suppressive effects of intranigral injection of muscimol in three models of generalized non-convulsive epilepsy induced by chemical agents. Brain research, 1989, Sep-25, Volume: 498, Issue:1 Topics: 4-Butyrolactone; Animals; Convulsants; Electroencephalography; Epilepsy; gamma-Aminobutyric Acid; Isoxazoles; Male; Muscimol; Pentylenetetrazole; Rats; Rats, Inbred Strains; Receptors, GABA-A; Substantia Nigra	1989
Late inhibitory postsynaptic potentials in rat prefrontal cortex may be mediated by GABAB receptors. Experientia, 1989, Feb-15, Volume: 45, Issue:2 Topics: Animals; Baclofen; Electric Conductivity; Electric Stimulation; Evoked Potentials; Frontal Lobe; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Isoxazoles; Male; Membrane Potentials; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Serotonin; Synapses	1989
3- and 5-isoxazolol zwitterions: an ab initio molecular orbital study relating to GABA agonism and antagonism. Journal of theoretical biology, 1987, Aug-21, Volume: 127, Issue:4 Topics: Chemical Phenomena; Chemistry; Crotonates; GABA Antagonists; Isoxazoles; Molecular Conformation; Muscimol; Pyridines; Receptors, GABA-A	1987
The modulation of cortical acetylcholine release by GABA, GABA-like drugs and benzodiazepines in freely moving guinea-pigs. Neuropharmacology, 1985, Volume: 24, Issue:4 Topics: Acetylcholine; Aminobutyrates; Animals; Anti-Anxiety Agents; Benzodiazepines; Cerebral Cortex; Ethanolamines; Female; gamma-Aminobutyric Acid; Guinea Pigs; Isoxazoles; Male; Muscimol; Serotonin Antagonists	1985
Quantitative electrocortical changes in the rat induced by phencyclidine and other stimulants. Neuropharmacology, 1985, Volume: 24, Issue:4 Topics: Animals; Apomorphine; Baclofen; Cerebral Cortex; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Dioxolanes; Electroencephalography; Isoquinolines; Isoxazoles; Male; Muscimol; Phencyclidine; Rats; Rats, Inbred Strains	1985
Excitatory amino acids: studies on the biochemical and chemical stability of ibotenic acid and related compounds. Journal of neurochemistry, 1985, Volume: 45, Issue:3 Topics: Animals; Brain; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Decarboxylation; Glutamates; Glutamic Acid; Hot Temperature; Hydrogen-Ion Concentration; Ibotenic Acid; Isoxazoles; Liver; Mice; Muscimol; Oxazoles; Pregnancy Proteins	1985
Intrinsic gamma aminobutyric acid receptors modulate the release of catecholamine from canine adrenal gland in situ. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:2 Topics: Adrenal Medulla; Animals; Baclofen; Bicuculline; Chromaffin Granules; Dogs; Electric Stimulation; Epinephrine; Female; Hexamethonium; Hexamethonium Compounds; Histocytochemistry; Isoxazoles; Muscimol; Naloxone; Norepinephrine; Receptors, GABA-A; Splanchnic Nerves	1986
Modulation of acetylcholine release from rat striatal slices by the GABA/benzodiazepine receptor complex. Life sciences, 1985, Feb-04, Volume: 36, Issue:5 Topics: Acetylcholine; Animals; Atropine; Baclofen; Benzodiazepinones; Clonazepam; Corpus Striatum; Electric Stimulation; Flumazenil; gamma-Aminobutyric Acid; Haloperidol; In Vitro Techniques; Isoxazoles; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A	1985
Modulation of [3H]diazepam binding in rat cortical membranes by GABAA agonists. Journal of neurochemistry, 1985, Volume: 44, Issue:4 Topics: Androstanes; Animals; Azasteroids; Bicuculline; Cell Membrane; Cerebral Cortex; Diazepam; GABA Antagonists; gamma-Aminobutyric Acid; Imidazoles; Isonicotinic Acids; Isoxazoles; Muscimol; Piperidines; Rats; Receptors, GABA-A; Taurine	1985
Effect of GABA agonists on the neurotoxicity and anticonvulsant activity of benzodiazepines. Life sciences, 1985, Feb-25, Volume: 36, Issue:8 Topics: Animals; Anticonvulsants; Benzodiazepines; Drug Synergism; Electroshock; Flunitrazepam; gamma-Aminobutyric Acid; Isoxazoles; Male; Mice; Muscimol; Nervous System; Receptors, GABA-A	1985
Evaluation of different GABA receptor agonists in the kindled amygdala seizure model in rats. Experimental neurology, 1985, Volume: 89, Issue:2 Topics: Amygdala; Animals; Female; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Isoxazoles; Kindling, Neurologic; Muscimol; Muscle Relaxation; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures	1985
Synthesis and pharmacological evaluation of cis-2,3,3a,4,5,6,7,7a-octahydro-3-oxoisoxazolo[5,4-c]pyridine: a structural analogue of the GABA agonist THIP. Journal of medicinal chemistry, 1985, Volume: 28, Issue:8 Topics: Animals; Anticonvulsants; Cerebellum; Electrophysiology; Female; Isoxazoles; Male; Mice; Muscimol; Oxazoles; Rats; Receptors, GABA-A	1985
GABA agonists. Resolution, absolute stereochemistry, and enantioselectivity of (S)-(+)- and (R)-(-)-dihydromuscimol. Journal of medicinal chemistry, 1985, Volume: 28, Issue:11 Topics: Animals; Bicuculline; Brain; Cats; Chemical Phenomena; Chemistry; Diazepam; gamma-Aminobutyric Acid; Isoxazoles; Molecular Conformation; Muscimol; Neurons; Oxazolidinones; Piperidines; Rats; Receptors, GABA-A; Spinal Cord; Stereoisomerism; Structure-Activity Relationship; Synaptic Membranes	1985
gamma-Aminobutyric acid agonists and antagonists alter chloride flux across brain membranes. Molecular pharmacology, 1986, Volume: 29, Issue:5 Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Animals; Baclofen; Bicuculline; Brain; Cell Membrane; Chlorides; gamma-Aminobutyric Acid; In Vitro Techniques; Isonicotinic Acids; Isoxazoles; Liver; Male; Mice; Mice, Inbred DBA; Muscimol; Picrotoxin; Receptors, GABA-A; Sodium; Sulfates; Taurine; Temperature	1986
Effects of the potentiation of the GABAergic neurotransmission in the olfactory bulbs on mouse-killing behavior. Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:3 Topics: Aggression; Aminocaproates; Animals; Brain Chemistry; Drug Synergism; gamma-Aminobutyric Acid; Isonicotinic Acids; Isoxazoles; Male; Motor Activity; Muscimol; Nipecotic Acids; Olfactory Bulb; Proline; Rats; Rats, Inbred Strains; Synaptic Transmission; Valproic Acid; Vigabatrin	1986
Effect of THIP and SL 76002, two clinically experimented GABA-mimetic compounds, on anterior pituitary GABA receptors and prolactin secretion in the rat. Life sciences, 1987, Mar-02, Volume: 40, Issue:9 Topics: Animals; Anticonvulsants; Bicuculline; Binding, Competitive; Female; gamma-Aminobutyric Acid; Haloperidol; Isoxazoles; Kinetics; Male; Muscimol; Ovariectomy; Oxazoles; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains; Receptors, GABA-A	1987
Effects of GABAergic drugs on the GABA turnover in the substantia nigra and the corpus striatum of the rat. Journal of neural transmission, 1987, Volume: 69, Issue:1-2 Topics: Alkynes; Aminocaproates; Animals; Baclofen; Bicuculline; Corpus Striatum; gamma-Aminobutyric Acid; Isoxazoles; Male; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Substantia Nigra	1987
Cardiorespiratory effects produced by injecting drugs that affect GABA receptors into nuclei associated with the ventral surface of the medulla. Neuropharmacology, 1987, Volume: 26, Issue:5 Topics: Animals; Bicuculline; Brain Mapping; Cardiovascular Physiological Phenomena; Cats; Female; gamma-Aminobutyric Acid; Isoxazoles; Male; Medulla Oblongata; Muscimol; Respiration; Synaptic Transmission	1987
Effect of GABAergic drugs in the behavioral 'despair' test in rats. European journal of pharmacology, 1986, Feb-18, Volume: 121, Issue:2 Topics: Acetates; Aminooxyacetic Acid; Animals; Baclofen; Behavior, Animal; Bicuculline; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Isoxazoles; Male; Motor Activity; Muscimol; Oxazoles; Picrotoxin; Rats	1986
Effects of GABA-mimetic drugs on turnover of histamine in the mouse brain. Japanese journal of pharmacology, 1986, Volume: 41, Issue:3 Topics: Aminooxyacetic Acid; Animals; Baclofen; Brain; Brain Chemistry; gamma-Aminobutyric Acid; Histamine; Isoxazoles; Male; Methylhistamines; Methylhistidines; Mice; Muscimol	1986
The effect of diazepam upon local cerebral glucose use in the conscious rat. Neuroscience, 1986, Volume: 19, Issue:1 Topics: Animals; Autoradiography; Brain Chemistry; Deoxy Sugars; Deoxyglucose; Diazepam; Energy Metabolism; gamma-Aminobutyric Acid; Humans; Injections, Intravenous; Isoxazoles; Male; Muscimol; Rats; Rats, Inbred Strains	1986
GABAergic mechanisms in antinociception. Progress in neuro-psychopharmacology & biological psychiatry, 1984, Volume: 8, Issue:4-6 Topics: Alkynes; Aminocaproates; Aminooxyacetic Acid; Analgesics; Animals; Baclofen; Bicuculline; Central Nervous System; gamma-Aminobutyric Acid; Isoxazoles; Mice; Muscimol; Pain; Rats; Stereoisomerism; Substance P; Synaptic Transmission; Vigabatrin	1984
Somatic and dendritic actions of gamma-aminobutyric acid agonists and uptake blockers in the hippocampus in vivo. Neuroscience, 1984, Volume: 12, Issue:2 Topics: Acetylcholine; Action Potentials; Animals; Dendrites; gamma-Aminobutyric Acid; Hippocampus; Isonicotinic Acids; Isoxazoles; Male; Muscimol; Rats; Synaptic Transmission	1984
GABAergic agents as anticonvulsants in baboons with photosensitive epilepsy. Neuroscience letters, 1984, Jun-29, Volume: 47, Issue:3 Topics: Aminocaproates; Animals; Anticonvulsants; Baclofen; Carbolines; Cerebral Cortex; Dose-Response Relationship, Drug; Epilepsies, Myoclonic; gamma-Aminobutyric Acid; Isoxazoles; Muscimol; Papio; Photic Stimulation; Receptors, Cell Surface; Receptors, GABA-A; Taurine; Vigabatrin	1984
Characteristics and distribution of muscimol binding sites in cat visual cortex. Brain research, 1984, Aug-13, Volume: 308, Issue:2 Topics: Animals; Autoradiography; Cats; gamma-Aminobutyric Acid; Isoxazoles; Kinetics; Muscimol; Oxazoles; Receptors, GABA-A; Tissue Distribution; Tritium; Visual Cortex	1984
Progesterone and estrogens in rat brain: modulation of GABA (gamma-aminobutyric acid) receptor activity. European journal of pharmacology, 1984, Aug-03, Volume: 103, Issue:1-2 Topics: Animals; Brain; Estrogens; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Isoxazoles; Kinetics; Muscimol; Nerve Tissue Proteins; Olfactory Bulb; Progesterone; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Neurotransmitter	1984
Action of pyrazolopyridines as modulators of [3H]flunitrazepam binding to the gaba/benzodiazepine receptor complex of the cerebellum. European journal of pharmacology, 1981, Mar-12, Volume: 70, Issue:2 Topics: Animals; Anti-Anxiety Agents; Bicuculline; Binding Sites; Cerebellum; Chlorides; Etazolate; Flunitrazepam; Isoxazoles; Male; Muscimol; Nicotinic Acids; Pyrazoles; Rats; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Tritium	1981
Stimulated release of 3H-glycine from retina. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1982, Volume: 218, Issue:1 Topics: Animals; Aporphines; Aspartic Acid; Cysteic Acid; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; Isoxazoles; Kainic Acid; Muscimol; Rabbits; Retina	1982
Relative disposition of the GABA agonists THIP and muscimol in the brain of the rat. The Journal of pharmacy and pharmacology, 1982, Volume: 34, Issue:10 Topics: Animals; Brain; gamma-Aminobutyric Acid; Isoxazoles; Male; Muscimol; Oxazoles; Rats; Rats, Inbred Strains; Time Factors	1982
GABA induces functionally active low-affinity GABA receptors on cultured cerebellar granule cells. Journal of neurochemistry, 1984, Volume: 43, Issue:6 Topics: Animals; Calcium; Cells, Cultured; Cerebellum; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Isoxazoles; Muscimol; Potassium; Rats; Rats, Inbred Strains; Receptors, GABA-A	1984
Heterogeneous depression of glucose utilization in the caudate nucleus by GABA agonists. Brain research, 1981, Mar-30, Volume: 209, Issue:2 Topics: Animals; Autoradiography; Blood Glucose; Caudate Nucleus; Isoxazoles; Male; Muscimol; Oxazoles; Rats; Receptors, Cell Surface; Receptors, GABA-A	1981
gamma-Aminobutyric acid- and benzodiazepine-binding sites in human anterior pituitary tissue. The Journal of clinical endocrinology and metabolism, 1982, Volume: 54, Issue:3 Topics: Adult; Aged; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Humans; Isonicotinic Acids; Isoxazoles; Middle Aged; Muscimol; Pituitary Gland, Anterior; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A	1982
Actions of GABAergic agents on dopamine metabolism in the nigrostriatal pathway of the rat. The Journal of pharmacology and experimental therapeutics, 1982, Volume: 222, Issue:3 Topics: 4-Aminobutyrate Transaminase; Aminooxyacetic Acid; Animals; Corpus Striatum; Diazepam; Dopamine; GABA Antagonists; gamma-Aminobutyric Acid; Isoxazoles; Male; Muscimol; Neural Pathways; Pyrones; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Substantia Nigra	1982
Glycine antagonists structurally related to muscimol, THIP, or isoguvacine. Journal of neurochemistry, 1982, Volume: 39, Issue:5 Topics: Animals; Cats; gamma-Aminobutyric Acid; Glycine; Interneurons; Isonicotinic Acids; Isoxazoles; Muscimol; Oxazoles; Rats; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Glycine; Spinal Cord; Structure-Activity Relationship	1982
Autoreceptors modify the evoked release of [3H]GABA from cerebellar neurons in dissociated cell culture. European journal of pharmacology, 1982, Aug-27, Volume: 82, Issue:3-4 Topics: Animals; Bicuculline; Cells, Cultured; Cerebellum; Fluspirilene; gamma-Aminobutyric Acid; Isoxazoles; Muscimol; Neurons; Potassium; Rats; Receptors, Cell Surface; Receptors, GABA-A	1982
GABAergic modulation of ethanol-induced motor impairment. The Journal of pharmacology and experimental therapeutics, 1982, Volume: 223, Issue:3 Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminobutyrates; Aminocaproates; Animals; Bicuculline; Brain; Ethanol; gamma-Aminobutyric Acid; Isoxazoles; Male; Motor Skills; Muscimol; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A	1982
Differential sensitivity of ethanol withdrawal signs in the rat to gamma-aminobutyric acid (GABA)mimetics: blockade of audiogenic seizures but not forelimb tremors. The Journal of pharmacology and experimental therapeutics, 1983, Volume: 226, Issue:3 Topics: 4-Aminobutyrate Transaminase; Acoustic Stimulation; Aminobutyrates; Animals; Chlordiazepoxide; Disease Susceptibility; Ethanol; Forelimb; gamma-Aminobutyric Acid; Humans; Isoxazoles; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Seizures; Substance Withdrawal Syndrome; Tremor	1983
GABA as a trophic factor during development. Life sciences, 1983, Sep-05, Volume: 33, Issue:10 Topics: Animals; Animals, Newborn; gamma-Aminobutyric Acid; Isoxazoles; Muscimol; Nipecotic Acids; Proline; Rabbits; Receptors, Cell Surface; Receptors, GABA-A; Retina	1983
Diazepam stimulates the binding of GABA and muscimol but not THIP to rat brain membranes. Neuroscience letters, 1983, Aug-08, Volume: 38, Issue:3 Topics: Analgesics; Animals; Brain; Diazepam; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Isoxazoles; Kinetics; Male; Muscimol; Oxazoles; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A	1983
Comparison of GABA analogues at the crayfish stretch receptor neurone. Brain research bulletin, 1983, Volume: 11, Issue:3 Topics: Animals; Astacoidea; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Isoxazoles; Mechanoreceptors; Membrane Potentials; Muscimol; Nipecotic Acids; Proline; Sodium	1983
Diazotization and thiocyanate differentiate agonists from antagonists for the high- and low-affinity receptors of gamma-aminobutyric acid. Journal of neurochemistry, 1984, Volume: 43, Issue:1 Topics: Androstanes; Animals; Azasteroids; Benzenesulfonates; Bicuculline; Cerebral Cortex; Diazonium Compounds; gamma-Aminobutyric Acid; Isoxazoles; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Sulfanilic Acids; Thiocyanates; Tubocurarine	1984
Pharmacological analysis of the central cardiovascular effects of four GABA analogues. Naunyn-Schmiedeberg's archives of pharmacology, 1984, Volume: 325, Issue:4 Topics: Animals; Atropine; Bicuculline; Blood Pressure; Brain; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; Isonicotinic Acids; Isoxazoles; Kainic Acid; Muscimol; Pyrones; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A	1984
Effect of apomorphine and gabaergic drugs in monkeys pretreated with haloperidol. Psychopharmacology, 1983, Volume: 79, Issue:2-3 Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Apomorphine; Chlorocebus aethiops; Female; gamma-Aminobutyric Acid; Haloperidol; Hemodynamics; Isoxazoles; Male; Motor Activity; Muscimol; Picrotoxin	1983
Enhancement of spike and wave discharges by GABAmimetic drugs in rats with spontaneous petit-mal-like epilepsy. Neuroscience letters, 1984, Jan-27, Volume: 44, Issue:1 Topics: Action Potentials; Aminocaproates; Animals; Baclofen; Epilepsy, Absence; gamma-Aminobutyric Acid; Isoxazoles; Muscimol; Rats; Vigabatrin	1984
Self-injurious behavior in rats produced by intranigral microinjection of GABA agonists. Pharmacology, biochemistry, and behavior, 1984, Volume: 21, Issue:1 Topics: Animals; Baclofen; Bicuculline; Brain; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Isoxazoles; Male; Microinjections; Muscimol; Rats; Rats, Inbred Strains; Self Mutilation; Stress, Physiological; Substantia Nigra	1984
Effects of intrathecally administered THIP, baclofen and muscimol on nociceptive threshold. European journal of pharmacology, 1984, Aug-03, Volume: 103, Issue:1-2 Topics: Animals; Baclofen; Injections, Spinal; Isoxazoles; Male; Muscimol; Muscle Hypotonia; Nociceptors; Oxazoles; Rats; Rats, Inbred Strains; Reaction Time; Sensory Thresholds	1984
The influence of GABAergic drugs on PGO activity in the cat. Neuropharmacology, 1983, Volume: 22, Issue:7 Topics: Alkynes; Aminocaproates; Animals; Brain; Cats; Chlordiazepoxide; Electroencephalography; Female; gamma-Aminobutyric Acid; Geniculate Bodies; Isoxazoles; Male; Muscimol; Occipital Lobe; Pons	1983
Unilateral injection of GABA agonists in the superior colliculus: asymmetry to tactile stimulation. Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:2 Topics: Analgesics; Animals; Baclofen; Functional Laterality; gamma-Aminobutyric Acid; Isoxazoles; Motor Activity; Muscimol; Oxazoles; Physical Stimulation; Rats; Rats, Inbred Strains; Superior Colliculi; Touch	1983
Nigral actions of GABA agonists are enhanced by chronic fluphenazine and differentiated by concomitant flurazepam. Psychopharmacology, 1982, Volume: 76, Issue:3 Topics: Animals; Baclofen; Bicuculline; Female; Fluphenazine; Flurazepam; gamma-Aminobutyric Acid; Humans; Isoxazoles; Muscimol; Rats; Rats, Inbred Strains; Stereotyped Behavior; Substantia Nigra	1982
Effects of the putative GABAergic agonists, muscimol and THIP, upon local cerebral glucose utilisation. Journal of neurochemistry, 1982, Volume: 39, Issue:3 Topics: Analgesics; Animals; Brain; Deoxy Sugars; Deoxyglucose; gamma-Aminobutyric Acid; Glycolysis; Isoxazoles; Male; Muscimol; Organ Specificity; Oxazoles; Rats; Rats, Inbred Strains	1982
Effects of GABA analogues and their interactions with morphine on locomotor activity in two inbred strains of mice. Pharmacological research communications, 1982, Volume: 14, Issue:5 Topics: Animals; Drug Interactions; gamma-Aminobutyric Acid; Isoxazoles; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Morphine; Motor Activity; Muscimol; Piracetam	1982
Analgesic properties of the GABA-mimetic THIP. European journal of pharmacology, 1981, Jan-16, Volume: 69, Issue:2 Topics: Analgesics; Animals; Arthritis, Experimental; Baclofen; Electric Stimulation; Isoxazoles; Macaca mulatta; Mice; Morphine; Muscimol; Oxazoles; Reaction Time	1981
Increases and decreases in local cerebral glucose utilization in response to GABA agonists. European journal of pharmacology, 1981, May-08, Volume: 71, Issue:2-3 Topics: Animals; Brain; gamma-Aminobutyric Acid; Glucose; Isoxazoles; Male; Muscimol; Oxazoles; Rats	1981
GABA in the entopeduncular nucleus and the subthalamic nucleus participates in mediating dopaminergic striatal output functions. Life sciences, 1981, Oct-12, Volume: 29, Issue:15 Topics: Animals; Behavior, Animal; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Injections, Intraventricular; Isoxazoles; Male; Mesencephalon; Muscimol; Neural Pathways; Picrotoxin; Rats; Rats, Inbred Strains; Thalamic Nuclei	1981
Etomidate stereospecifically stimulates forebrain, but not cerebellar, 3H-diazepam binding. Life sciences, 1981, Dec-21, Volume: 29, Issue:25 Topics: Animals; Brain; Cerebellum; Diazepam; Etomidate; Female; gamma-Aminobutyric Acid; Imidazoles; Isoxazoles; Muscimol; Rats; Rats, Inbred Strains; Stereoisomerism; Synaptic Membranes	1981
Paradoxical blockade of a muscimol response by THIP, a GABA agonist and also by GABA-transaminase inhibitors. Neuropharmacology, 1981, Volume: 20, Issue:12A Topics: 4-Aminobutyrate Transaminase; Animals; gamma-Aminobutyric Acid; Isoxazoles; Male; Mice; Muscimol; Myoclonus; Oxazoles; Time Factors; Transaminases	1981
Single unit responses of substantia nigra and globus pallidus neurons to GABA agonist and antagonist drugs. Advances in biochemical psychopharmacology, 1981, Volume: 30 Topics: Animals; gamma-Aminobutyric Acid; Globus Pallidus; Iontophoresis; Isoxazoles; Kainic Acid; Male; Muscimol; Neurons; Oxazoles; Rats; Rats, Inbred Strains; Substantia Nigra	1981
Interaction between phencyclidine (PCP) and GABA-ergic drugs: clinical implications. Pharmacology, biochemistry, and behavior, 1980, Volume: 12, Issue:1 Topics: Aminooxyacetic Acid; Anesthesia; Animals; Baclofen; Dextroamphetamine; Diazepam; Drug Interactions; gamma-Aminobutyric Acid; Isoxazoles; Male; Mice; Motor Activity; Muscimol; Pain; Phencyclidine; Reflex	1980
GABAergic actions of THIP in vivo and vitro: a comparison with muscimol and GABA. European journal of pharmacology, 1980, Jul-11, Volume: 65, Issue:1 Topics: Animals; Binding Sites; Brain; Cerebellum; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; In Vitro Techniques; Iontophoresis; Isoxazoles; Male; Muscimol; Neurons; Oxazoles; Rats; Substantia Nigra	1980
Intravenous GABA agonist administration stimulates firing of A10 dopaminergic neurons. European journal of pharmacology, 1980, Aug-22, Volume: 66, Issue:1 Topics: Animals; Dopamine; gamma-Aminobutyric Acid; Injections, Intravenous; Isoxazoles; Limbic System; Muscimol; Neurons; Rats	1980
Pharmacological subtypes of the gamma-aminobutyric acidA receptors defined by a gamma-aminobutyric acid analogue 4,5,6,7-tetrahydroisoxazolo[5,4-c] pyridin-3-ol and allosteric coupling: characterization using subunit-specific antibodies. Molecular pharmacology, 1995, Volume: 48, Issue:4 Topics: Allosteric Regulation; Amino Acid Sequence; Animals; Antibodies; Antibody Specificity; Benzodiazepines; Binding Sites; Binding, Competitive; Blotting, Western; Cattle; GABA Agonists; gamma-Aminobutyric Acid; Isoxazoles; Kinetics; Macromolecular Substances; Molecular Sequence Data; Muscimol; Precipitin Tests; Rabbits; Rats; Receptors, GABA-A; Sensitivity and Specificity; Sequence Homology, Amino Acid; Tritium	1995
Age-related differences in the effects of GABAA agonists microinjected into rat substantia nigra: pro- and anticonvulsant actions. Epilepsia, 1995, Volume: 36, Issue:10 Topics: Age Factors; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Flurothyl; GABA Agonists; gamma-Aminobutyric Acid; Isoxazoles; Male; Microinjections; Muscimol; Rats; Rats, Sprague-Dawley; Seizures; Substantia Nigra	1995
Identification of a second glycine-like fragment on the strychnine molecule. Journal of neuroscience research, 1995, Feb-15, Volume: 40, Issue:3 Topics: Azepines; Glycine; Isoxazoles; Models, Molecular; Muscimol; Strychnine	1995
Molecular pharmacology of gamma-aminobutyric acid type A receptor agonists and partial agonists in oocytes injected with different alpha, beta, and gamma receptor subunit combinations. Molecular pharmacology, 1994, Volume: 46, Issue:5 Topics: Animals; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Humans; Isoxazoles; Muscimol; Oocytes; Oxazolidinones; Piperidines; Receptors, GABA-A; Recombinant Proteins; Structure-Activity Relationship; Xenopus	1994
GABA alters GABAA receptor mRNAs and increases ligand binding. Journal of neurochemistry, 1993, Volume: 61, Issue:6 Topics: Animals; Anticonvulsants; Base Sequence; Bicuculline; Cells, Cultured; Cerebellum; DNA Primers; gamma-Aminobutyric Acid; Gene Expression; Isoxazoles; Macromolecular Substances; Molecular Sequence Data; Muscimol; Neurons; Polymerase Chain Reaction; Rats; Receptors, GABA-A; RNA, Messenger	1993
GABAergic cells and signals appear together in the early post-mitotic period of telencephalic and striatal development. Brain research. Developmental brain research, 1993, Jun-08, Volume: 73, Issue:2 Topics: Acridine Orange; Animals; Corpus Striatum; Female; Flow Cytometry; Fluorescent Dyes; gamma-Aminobutyric Acid; Immunohistochemistry; Intermediate Filaments; Isoxazoles; Mitosis; Muscimol; Neuromuscular Depolarizing Agents; Phenotype; Pregnancy; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium Channels; Telencephalon	1993
Neuronal regulation of astrocyte morphology in vitro is mediated by GABAergic signaling. Glia, 1997, Volume: 20, Issue:1 Topics: Animals; Animals, Newborn; Astrocytes; Baclofen; Bicuculline; Cell Adhesion; Cells, Cultured; Coculture Techniques; GABA Agonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Isoxazoles; Muscimol; Neurons; Rats; Rats, Wistar; Signal Transduction; Sodium Channel Blockers; Tetrodotoxin; Time Factors	1997
Differences in agonist/antagonist binding affinity and receptor transduction using recombinant human gamma-aminobutyric acid type A receptors. Molecular pharmacology, 1997, Volume: 52, Issue:6 Topics: Animals; Binding, Competitive; DNA, Complementary; Electrophysiology; GABA Agonists; GABA Antagonists; Humans; Isoxazoles; Kinetics; Macromolecular Substances; Muscimol; Oocytes; Piperidines; Receptors, GABA-A; Transduction, Genetic; Transfection; Tritium; Xenopus laevis	1997
Activity at the GABA transporter contributes to acute cellular swelling produced by metabolic impairment in retina. Vision research, 1997, Volume: 37, Issue:24 Topics: Animals; Biological Transport; Carbon Radioisotopes; Carrier Proteins; Chick Embryo; Culture Techniques; GABA Agonists; GABA Antagonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Glycolysis; Iodoacetates; Ischemia; Isoxazoles; Membrane Proteins; Membrane Transport Proteins; Muscimol; Nipecotic Acids; Organic Anion Transporters; Oximes; Proline; Retina	1997
gamma-Aminobutyric acidA agonists differentially augment gnawing induced by indirect-acting dopamine agonists in C57BL/6J mice. The Journal of pharmacology and experimental therapeutics, 1998, Volume: 284, Issue:1 Topics: Animals; Behavior, Animal; Benzazepines; Cocaine; Dopamine Agonists; GABA-A Receptor Agonists; Isoxazoles; Male; Mice; Mice, Inbred C57BL; Muscimol; Piperazines	1998
Neurosteroid inhibition of cell death. The American journal of physiology, 1997, Volume: 273, Issue:6 Topics: Alkaloids; Animals; Antimycin A; Benzylisoquinolines; Calcium; Cell Death; Cell Hypoxia; Cells, Cultured; Dehydroepiandrosterone Sulfate; Female; gamma-Aminobutyric Acid; Isoxazoles; Kidney Tubules, Proximal; Kinetics; L-Lactate Dehydrogenase; Mitochondria; Muscimol; Oxygen Consumption; Pregnanes; Rabbits; Receptors, GABA-A	1997
[Receptor mechanism of the neuroprotective effect of GABAergic agents]. Biulleten' eksperimental'noi biologii i meditsiny, 1998, Volume: 125, Issue:2 Topics: Animals; Baclofen; Brain Ischemia; Female; GABA Agonists; GABA Antagonists; Injections, Intraventricular; Injections, Subcutaneous; Isonipecotic Acids; Isoxazoles; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Muscimol; Neuroprotective Agents; Receptors, GABA-A; Receptors, GABA-B	1998
Defining affinity with the GABAA receptor. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Nov-01, Volume: 18, Issue:21 Topics: Animals; Animals, Newborn; beta-Alanine; Cells, Cultured; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Hippocampus; Isoxazoles; Ligands; Muscimol; Neurons; Patch-Clamp Techniques; Pyridazines; Rats; Receptors, GABA-A	1998
Mechanism by which GABA, through its GABA(A) receptor, modulates glutamate release from rat cortical neurons in culture. Neurochemistry international, 1999, Volume: 34, Issue:2 Topics: Animals; Barbiturates; Calcium; Cells, Cultured; Cerebral Cortex; Chloride Channels; Chlorides; Fluorescence; Fluorescent Dyes; gamma-Aminobutyric Acid; Glutamic Acid; Ion Transport; Isoxazoles; Membrane Potentials; Muscimol; Neurons; Potassium Chloride; Rats; Receptors, GABA-A	1999
A novel route to 5-substituted 3-isoxazolols. Cyclization of N, O-DiBoc beta-keto hydroxamic acids synthesized via acyl Meldrum's acids. The Journal of organic chemistry, 2000, Feb-25, Volume: 65, Issue:4 Topics: Agaricales; Cyclization; Dioxanes; GABA Agonists; Hydrochloric Acid; Hydroxamic Acids; Insecticides; Isoxazoles; Magnetic Resonance Spectroscopy; Mass Spectrometry; Muscimol	2000
Entropy as the predominant driving force of binding to human recombinant alpha(x)beta(3)gamma(2) GABA(A) receptors. European journal of pharmacology, 2001, Jan-05, Volume: 411, Issue:1-2 Topics: Animals; Binding, Competitive; Dose-Response Relationship, Drug; Entropy; GABA Agonists; GABA Antagonists; Humans; Isoxazoles; L Cells; Membranes; Mice; Muscimol; Piperidines; Pyridazines; Receptors, GABA-A; Recombinant Proteins; Temperature; Tritium	2001
A novel class of potent 3-isoxazolol GABA(A) antagonists: design, synthesis, and pharmacology. Journal of medicinal chemistry, 2000, Dec-28, Volume: 43, Issue:26 Topics: Animals; Brain; Cells, Cultured; GABA Antagonists; Isoxazoles; Models, Molecular; Muscimol; Neurons; Patch-Clamp Techniques; Piperidines; Radioligand Assay; Rats; Receptors, GABA-A; Structure-Activity Relationship; Synaptic Membranes	2000
Additivity and independence of neuroprotective effects of GABAA and GABAB receptor agonists in complete global cerebral ischemia. Bulletin of experimental biology and medicine, 2000, Volume: 130, Issue:8 Topics: Animals; Baclofen; Bicuculline; Brain Ischemia; Drug Interactions; Female; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Isoxazoles; Male; Mice; Mice, Inbred CBA; Muscimol; Neuroprotective Agents; Picrotoxin	2000
Microscopic kinetics and energetics distinguish GABA(A) receptor agonists from antagonists. Biophysical journal, 2001, Volume: 81, Issue:5 Topics: Animals; Brain; Diffusion; Electrophysiology; Energy Metabolism; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Inhibitory Concentration 50; Isoxazoles; Kinetics; Muscimol; Phosphinic Acids; Protein Binding; Pyridazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A	2001
GABAergic and glutamatergic terminals differentially influence the organization of GABAergic synapses in rat cerebellar granule cells in vitro. Neuroscience, 2002, Volume: 114, Issue:1 Topics: Age Factors; Animals; Animals, Newborn; Bicuculline; Carrier Proteins; Cell Differentiation; Cells, Cultured; Cerebellar Cortex; Fluorescent Antibody Technique; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Isoxazoles; Membrane Proteins; Membrane Transport Proteins; Muscimol; Presynaptic Terminals; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptic Membranes; Synaptic Transmission; Vesicular Glutamate Transport Protein 1; Vesicular Transport Proteins	2002
The GABAA receptor agonist THIP is neuroprotective in organotypic hippocampal slice cultures. Brain research, 2003, May-30, Volume: 973, Issue:2 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Animals, Newborn; Cell Death; Dose-Response Relationship, Drug; Glutamate Decarboxylase; Hippocampus; Isoxazoles; Kainic Acid; Muscimol; N-Methylaspartate; Neuroprotective Agents; Organ Culture Techniques; Propidium; Pyramidal Cells; Rats; Rats, Wistar; Time Factors	2003
Changes in rectal temperature and ECoG spectral power of sensorimotor cortex elicited in conscious rabbits by i.c.v. injection of GABA, GABA(A) and GABA(B) agonists and antagonists. British journal of pharmacology, 2004, Volume: 141, Issue:1 Topics: Animals; Baclofen; Behavior, Animal; Bicuculline; Body Temperature Regulation; Electroencephalography; GABA Agonists; GABA Antagonists; Injections, Intraventricular; Isoxazoles; Lateral Ventricles; Male; Muscimol; Nipecotic Acids; Preoptic Area; Rabbits; Receptors, GABA-A; Receptors, GABA-B; Rectum; Somatosensory Cortex	2004
Charged residues at the 2' position of human GABAC rho 1 receptors invert ion selectivity and influence open state probability. The Journal of biological chemistry, 2004, Dec-24, Volume: 279, Issue:52 Topics: Amino Acid Sequence; Amino Acids, Cyclic; Binding Sites; Carboxylic Acids; Cations; Crotonates; Cyclopropanes; Dose-Response Relationship, Drug; Electric Conductivity; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Imidazoles; Ion Channel Gating; Isoxazoles; Molecular Sequence Data; Molecular Structure; Muscimol; Mutagenesis, Site-Directed; Proline; Protein Subunits; Receptors, GABA; Static Electricity; Structure-Activity Relationship	2004
Centrally-mediated antinociceptive actions of GABA(A) receptor agonists in the rat spared nerve injury model of neuropathic pain. European journal of pharmacology, 2005, Jun-01, Volume: 516, Issue:2 Topics: Analgesics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; GABA Agonists; GABA-A Receptor Agonists; Isonicotinic Acids; Isoxazoles; Male; Muscimol; Neuralgia; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Stress, Mechanical; Time Factors; Trauma, Nervous System; Zolpidem	2005
Involvement of GABAergic modulation of antinociception induced by morphine microinjected into the ventrolateral orbital cortex. Brain research, 2006, Feb-16, Volume: 1073-1074 Topics: Analysis of Variance; Animals; Behavior, Animal; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Isoxazoles; Male; Microinjections; Morphine; Muscimol; Narcotics; Neurons; Nociceptors; Pain Measurement; Picrotoxin; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reaction Time	2006
The progesterone metabolite allopregnanolone potentiates GABA(A) receptor-mediated inhibition of 5-HT neuronal activity. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2007, Jan-15, Volume: 17, Issue:2 Topics: Action Potentials; Analysis of Variance; Anesthetics; Animals; Drug Interactions; Female; GABA Agonists; In Vitro Techniques; Isoxazoles; Muscimol; Neural Inhibition; Neurons; Pregnanolone; Progesterone; Raphe Nuclei; Rats; Receptors, GABA-A; Serotonin; Time Factors	2007
delta-Subunit containing GABAA receptor knockout mice are less sensitive to the actions of 4,5,6,7-tetrahydroisoxazolo-[5,4-c]pyridin-3-ol. European journal of pharmacology, 2006, Jul-17, Volume: 541, Issue:3 Topics: Animals; Cells, Cultured; Cerebellum; Cerebral Cortex; Female; GABA Agonists; Isoxazoles; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscimol; Receptors, GABA-A	2006
GABAergic modulation of binge-like ethanol intake in C57BL/6J mice. Pharmacology, biochemistry, and behavior, 2007, Volume: 88, Issue:1 Topics: Alcoholism; Animals; Baclofen; Central Nervous System Depressants; Darkness; Dose-Response Relationship, Drug; Ethanol; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Isoxazoles; Male; Mice; Mice, Inbred C57BL; Muscimol; Postural Balance	2007
Transport of amino acids and GABA analogues via the human proton-coupled amino acid transporter, hPAT1: characterization of conditions for affinity and transport experiments in Caco-2 cells. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2008, Sep-02, Volume: 35, Issue:1-2 Topics: Algorithms; Amino Acid Transport Systems; Amino Acids; Biological Transport, Active; Caco-2 Cells; GABA Agonists; gamma-Aminobutyric Acid; Glycine; Humans; Hydrogen-Ion Concentration; Isoxazoles; Kinetics; Ligands; Muscimol; Neurotransmitter Uptake Inhibitors; Osmolar Concentration; Proline; Symporters	2008
Synthesis of GABAA receptor agonists and evaluation of their alpha-subunit selectivity and orientation in the GABA binding site. Journal of medicinal chemistry, 2008, Aug-14, Volume: 51, Issue:15 Topics: Animals; Binding Sites; Brain; Cell Line; Electrophysiology; Female; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Humans; Isoxazoles; Models, Molecular; Molecular Structure; Muscimol; Mutation; Oocytes; Patch-Clamp Techniques; Piperidines; Protein Subunits; Rats; Receptors, GABA-A; Structure-Activity Relationship; Xenopus laevis	2008
Regulation of light's action in the mammalian circadian clock: role of the extrasynaptic GABAA receptor. American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 296, Issue:5 Topics: Animals; Circadian Rhythm; Cricetinae; GABA Agonists; GABA-A Receptor Agonists; Intracellular Signaling Peptides and Proteins; Isoxazoles; Male; Mesocricetus; Muscimol; Period Circadian Proteins; Photoperiod; Receptors, GABA-A; RNA, Messenger; Suprachiasmatic Nucleus	2009
Distinct activities of GABA agonists at synaptic- and extrasynaptic-type GABAA receptors. The Journal of physiology, 2010, Apr-15, Volume: 588, Issue:Pt 8 Topics: Animals; Cell Line; Dose-Response Relationship, Drug; Electrophysiological Phenomena; Fibroblasts; GABA Agonists; gamma-Aminobutyric Acid; Humans; Hydrogen-Ion Concentration; Isoxazoles; Kidney; Mice; Muscimol; Patch-Clamp Techniques; Receptors, GABA-A; Synapses; Transfection	2010
Pulvinar inactivation disrupts selection of movement plans. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Jun-23, Volume: 30, Issue:25 Topics: Animals; Behavior, Animal; Brain Mapping; Decision Making; Electrophysiology; Eye Movements; Female; GABA Agonists; Isoxazoles; Macaca mulatta; Magnetic Resonance Imaging; Male; Motor Activity; Muscimol; Neurons; Pulvinar; Visual Fields	2010
Modulation of spinal GABAergic analgesia by inhibition of chloride extrusion capacity in mice. The journal of pain, 2012, Volume: 13, Issue:6 Topics: Analgesia; Analgesics; Animals; Benzodiazepines; Chlorides; GABA-A Receptor Agonists; Isoxazoles; K Cl- Cotransporters; Male; Mice; Mice, Inbred ICR; Muscimol; Neuralgia; Peripheral Nerve Injuries; Pregnanolone; Receptors, GABA-A; Sciatic Nerve; Symporters	2012
Extrasynaptic GABAA receptors in rat pontine reticular formation increase wakefulness. Sleep, 2013, Mar-01, Volume: 36, Issue:3 Topics: Animals; Electroencephalography; GABA Agonists; GABA-A Receptor Agonists; Isoxazoles; Male; Microinjections; Muscimol; Pons; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Reticular Formation; Sleep; Sodium Chloride; Wakefulness	2013
Diabetes induces GABA receptor plasticity in murine vagal motor neurons. Journal of neurophysiology, 2015, Volume: 114, Issue:1 Topics: Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; GABA Agonists; GABA-A Receptor Agonists; Immunohistochemistry; Isoxazoles; Male; Membrane Potentials; Mice; Motor Neurons; Muscimol; Neuronal Plasticity; Patch-Clamp Techniques; Real-Time Polymerase Chain Reaction; Receptors, GABA-A; Synapses; Vagus Nerve	2015
4,5-Substituted 3-Isoxazolols with Insecticidal Activity Act as Competitive Antagonists of Housefly GABA Receptors. Journal of agricultural and food chemistry, 2015, Jul-22, Volume: 63, Issue:28 Topics: Animals; Binding, Competitive; GABA Antagonists; Gene Expression; Houseflies; Insecticides; Isoxazoles; Models, Molecular; Molecular Structure; Muscimol; Oocytes; Oxazoles; Receptors, GABA; Xenopus laevis	2015
Involvement of the GABAA Receptor in Age-Dependent Differences in Binge-Like Ethanol Intake. Alcoholism, clinical and experimental research, 2016, Volume: 40, Issue:2 Topics: Age Factors; Animals; Binge Drinking; GABA-A Receptor Agonists; Isoxazoles; Male; Mice; Mice, Inbred C57BL; Muscimol; Receptors, GABA-A	2016
Reduced GABAergic transmission in the ventrobasal thalamus contributes to thermal hyperalgesia in chronic inflammatory pain. Scientific reports, 2017, 02-02, Volume: 7 Topics: Animals; Chronic Pain; Extracellular Space; Freund's Adjuvant; GABAergic Neurons; gamma-Aminobutyric Acid; Gene Knockout Techniques; Hyperalgesia; Inflammation; Isoxazoles; Male; Muscimol; Optogenetics; Patch-Clamp Techniques; Protein Subunits; Rats, Sprague-Dawley; Receptors, GABA-A; Synaptic Transmission; Thalamus	2017