muscimol has been researched along with gamma-aminobutyric acid in 1573 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 764 (48.57) | 18.7374 |
| 1990's | 434 (27.59) | 18.2507 |
| 2000's | 252 (16.02) | 29.6817 |
| 2010's | 106 (6.74) | 24.3611 |
| 2020's | 17 (1.08) | 2.80 |
| Authors | Studies |
|---|---|
| Atkinson, JG; Girard, Y; McFarlane, CS; Rackham, A; Rokach, J; Rooney, CS; Share, NN | 1 |
| Chambon, JP; Melikian, A; Schlewer, G; Wermuth, CG | 1 |
| Ali, FE; Bondinell, WE; Dandridge, PA; Frazee, JS; Garvey, E; Girard, GR; Kaiser, C; Ku, TW; Lafferty, JJ; Moonsammy, GI | 1 |
| Curtis, DR; Falch, E; Krogsgaard-Larsen, P; Nielsen, L | 1 |
| Berthelot, P; Debaert, M; Flouquet, N; Luyckx, M; Musadad, A; Vaccher, C | 1 |
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Enna, SJ; Patch, RJ; Tomita, K; Witiak, DT | 1 |
| Bartholini, G; Desarmenien, M; Feltz, P; Headley, PM; Kaplan, JP; Lloyd, KG; Raizon, BM; Worms, P | 1 |
| Azzaro, AJ; Johnson, DA; O'Donnell, JP | 1 |
| Bauer, C; Caldwell, L; Kinnier, WJ; Lancaster, J; McMillan, B; Price, CH; Sweetnam, PM | 1 |
| Chebib, M; Johnston, GA | 2 |
| Bang-Andersen, B; Ebert, B; Frølund, B; Hansen, CP; Jensen, AA; Kristiansen, U; Krogsgaard-Larsen, P; Larsen, M; Liljefors, T; Madsen, C; Nielsen, B | 1 |
| Chebib, M; Hanrahan, JR; Hibbs, DE; Johnston, GA; Kim, HL; Kumar, RJ; Salam, NK | 1 |
| Balle, T; Bergmann, R; Frydenvang, K; Frølund, B; Jensen, AA; Jørgensen, CG; Kehler, J; Kristensen, J; Kristiansen, U; Møller, HA; Nielsen, B; Petersen, JG | 1 |
| Chebib, M; Doddareddy, MR; Gavande, N; Hanrahan, JR; Johnston, GA; Kim, HL | 1 |
| Balle, T; Bergmann, R; Damgaard, M; Frølund, B; Jensen, AA; Nielsen, B; Petersen, JG; Sørensen, T | 1 |
| Waddington, JL | 1 |
| Arnt, J; Christensen, AV; Scheel-Krüger, J | 1 |
| Kamioka, T; Matsui, Y | 1 |
| Chase, TN; Crayton, JW; Tamminga, CA | 1 |
| Arnt, J; Krogsgaard-Larsen, P; Magelund, G; Scheel-Krüger, J | 1 |
| Arnt, J; Scheel-Krüger, J | 2 |
| Andrews, PR; Johnston, GA | 2 |
| Kuhar, MJ; Niehoff, DL; Palacios, JM | 1 |
| Crossman, AR; Lee, LA; Longman, DA; Slater, P | 1 |
| Haefely, W | 1 |
| Meldrum, BS | 2 |
| Cheney, DL; Costa, E; Wood, PL | 1 |
| King, GA | 1 |
| Baker, HF; Ridley, RM; Scraggs, PR | 1 |
| Haubrich, DR; Williams, M; Yarbrough, GG | 1 |
| Lodge, D | 1 |
| James, TA; Straughan, DW | 1 |
| Charlton, M; Goldblatt, D; Joynt, RJ; Shoulson, I | 1 |
| Chase, TN; Frohman, LA; Neophytides, A; Tamminga, CA | 1 |
| Fang, VS; Meltzer, HY; Simonovic, M | 1 |
| Greenlee, DV; Olsen, RW; Van Ness, PC | 1 |
| Bowery, NG; Collins, JF; Hudson, AL; Neal, MJ | 1 |
| Cross, AJ; Waddington, JL | 3 |
| Cheney, DL; Costa, E; Moroni, F; Peralta, E | 1 |
| Chan-Palay, V; Palay, S; Yonezawa, T; Yoshida, S | 1 |
| Bertilsson, L | 1 |
| Arbilla, S; Langer, SZ | 1 |
| Greenlee, DV; Olsen, RW | 1 |
| Maderdrut, JL; Oppenheim, RW; Reitzel, JL | 1 |
| Arbilla, S; Kamal, L; Langer, SZ | 1 |
| Beaumont, K; Fibiger, HC; Nagy, JI; Reisine, TD; Yamamura, HI | 1 |
| Arnt, J; Krogsgaard-Larsen, P | 2 |
| Biggio, G; Casu, M; Corda, MG; Gessa, GL; Mulas, ML | 1 |
| Longman, DA; Slater, P | 1 |
| Cross, AL; Waddington, JL | 1 |
| DeFeudis, FV; Mandel, P; Ossola, L; Schmitt, G | 2 |
| Desarmenien, M; Feltz, P; Headley, PM | 2 |
| Matthews, WD; McCafferty, GP | 1 |
| Karobath, M; Sperk, G | 1 |
| Sethy, VH | 1 |
| Ciesielski, L; Kempf, E; Mack, G; Maitre, M; Mandel, P; Simler, S | 1 |
| Polc, P | 1 |
| Risley, EA; Williams, M | 2 |
| Kehoe, P; Meiners, BM; Olsen, RW; Shaner, DM | 1 |
| Andén, NE; Grabowska-Andén, M; Wachtel, H | 1 |
| Horng, JS; Wong, DT | 1 |
| Roberts, E; Salvaterra, P; Wang, YJ | 1 |
| Curtis, DR; Hjeds, H; Johnston, GA; Krogsgaard-Larsen, P; Lodge, D | 1 |
| Enna, SJ; Maggi, A | 1 |
| DiMicco, JA; Gale, K; Gillis, RA; Hamilton, B | 1 |
| Baldessarini, RJ; Herschel, M | 1 |
| Braestrup, C; Falch, E; Krogsgaard-Larsen, P; Nielsen, M | 2 |
| Maurer, R | 2 |
| Jenner, P; Leigh, N; Marsden, CD; Reavill, C | 2 |
| Marusov, IV; Val'dman, AV | 1 |
| Grandison, L; Guidotti, A | 1 |
| Betti, R; Cocchi, D; Frigerio, C; Krogsgaard-Larsen, P; Locatelli, V; Müller, EE; Racagni, G | 1 |
| Bartholini, G; Scatton, B | 4 |
| Baertschi, AJ; Dreifuss, JJ; Zingg, HH | 1 |
| Chude, O | 1 |
| Cheney, DL; Costa, E; Revuelta, AV; Wood, PL | 1 |
| Chéramy, A; Glowinski, J; Leviel, V; Nieoullon, A | 1 |
| Gross, DM; Sweet, CS; Wenger, HC | 1 |
| Chang, RS; Gavish, M; Snyder, SH | 1 |
| Frey, HH; Löscher, W; Popp, C | 1 |
| Franco, S; Schlosser, W | 1 |
| Karobath, M; Lippitsch, M | 1 |
| Przewłocka, B; Scheel-Krüger, J; Stala, L | 1 |
| Bowery, NG; Collins, JF; Cryer, G; Inch, TD; McLaughlin, NJ | 1 |
| DeFeudis, FV; Mandel, P; Ossola, L | 3 |
| Bunney, BS; Grace, AA | 1 |
| Grossman, SP; Kelly, J; Rothstein, J | 1 |
| Johnston, GA; Kennedy, SM; Lodge, D | 1 |
| Curtis, DR; Johnston, GA; Lodge, D | 1 |
| Chan-Palay, V | 1 |
| Bacino, CB; Martin, GE; Papp, NL | 1 |
| Arnt, J; Braestrup, C; Christensen, AV; Cools, AR; Magelund, G; Scheel-Krüger, J | 1 |
| Jobert, A; Soubrié, P; Thiébot, MH | 1 |
| Delini-Stula, A; Vassout, A | 2 |
| Soubrié, P; Thiébot, MH | 1 |
| Depoortere, H; Lloyd, KG; Worms, P | 1 |
| Di Chiara, G; Gessa, GL; Morelli, M; Porceddu, ML | 1 |
| Gower, M; MacNeil, D; Szymanska, I | 1 |
| Antonaccio, MJ; Kerwin, L; Taylor, DG | 1 |
| Briley, MS; Langer, SZ | 1 |
| Carlà, V; Giotti, A; Magnani, M; Sgaragli, GP | 1 |
| Hara, N; Ichinose, M; Sawada, M | 1 |
| Harbarth, P; Licht, P; Merz, WE | 1 |
| Ehrmann, ML; Mileson, BE; Schwartz, RD | 1 |
| Chen, TF; Doyle, PT; Ferguson, DR | 1 |
| Conzelmann, U; Meyer, DK; Müller, A | 1 |
| Bourdelais, AJ; Kalivas, PW | 1 |
| Furuya, N; Yabe, T | 1 |
| Carbone, S; Moguilevsky, JA; Szwarcfarb, B | 1 |
| DeWitte, P; Kalivas, PW; Klitenick, MA | 1 |
| Aprison, MH; Lipkowitz, KB | 1 |
| Edgar, PP; Schwartz, RD | 1 |
| Dean, P; Redgrave, P | 1 |
| Bertrand, PP; Galligan, JJ | 1 |
| Bach, F; Flügge, G; Wuttke, W | 1 |
| Ennis, C; Lattimer, N; Lloyd, GK; Minchin, MC; White, AC; White, JF | 1 |
| Schwartz, RD; Yu, X | 2 |
| Hales, TG; Kim, H; Longoni, B; Olsen, RW; Tobin, AJ | 1 |
| Brandão, ML; Cardoso, SH; Melo, LL | 1 |
| Skolnick, P; Wong, G | 1 |
| Kuriyama, K; Ueha, T | 1 |
| Brown, LL; Moshé, SL; Sperber, EF; Tempel, A | 1 |
| Benoliel, JJ; Bourgoin, S; Cesselin, F; Hamon, M; Legrand, JC; Mauborgne, A; Pohl, M | 1 |
| Gale, K | 2 |
| Durkin, TP | 1 |
| Ebbesson, SO; Erdö, SL; Hofmann, MH; Malz, CR; Meyer, DL | 1 |
| Kaneto, H; Takahashi, M; Tokuyama, S | 1 |
| Bao, J; Lee, YH; Tang, XW; Tsai, WH; Wu, E; Wu, JY; Yarom, M | 1 |
| Linn, DM; Massey, SC | 1 |
| Berger, T; Kettenmann, H; Schnitzer, J; Walz, W | 1 |
| Davidson, K; Gillies, G | 1 |
| Donoso, AO; López, FJ; Negro-Vilar, A | 1 |
| da Cunha, C; Ferreira, MB; Izquierdo, I; Jerusalinsky, D; Medina, JH; Rosat, R | 1 |
| Birt, A; Cassady, SL; Moran, M; Tamminga, CA; Thaker, GK | 1 |
| Blessing, WW; Gieroba, ZJ | 1 |
| Scarth, BA; Shaw, C | 2 |
| Takeuchi, H | 1 |
| Bountra, C; Kaila, K; Pasternack, M; Voipio, J | 1 |
| Allan, AM; Baier, LD | 1 |
| Veruki, ML; Yeh, HH | 1 |
| Benoliel, JJ; Bourgoin, S; Cesselin, F; Collin, E; Hamon, M; Mauborgne, A; Pohl, M | 1 |
| Bouchet, MJ; Goeldner, M; Hirth, C; Ilien, B; Jacques, P | 1 |
| Kubota, K; Matsumura, M; Sawaguchi, T | 1 |
| Kertser, SL | 1 |
| Kaila, K; Pasternack, M; Rydqvist, B; Voipio, J | 1 |
| Gaioni, SJ; Riquimaroux, H; Suga, N | 1 |
| Borycz, J; Borycz, JA; Bugajski, J | 1 |
| Marc, RE; Massey, SC; Mills, SL | 1 |
| Hao, JX; Seiger, A; Wiesenfeld-Hallin, Z; Xu, XJ; Yu, YX | 1 |
| Castresana, A; Emmanouilidis, E; Payan, C; Poenaru, S; Rouhani, S; Soulairac, A; Tran, G | 1 |
| Chang, JP; Dubourg, P; Kah, O; Peter, RE; Sloley, BD; Trudeau, VL; Yu, KL | 1 |
| Dutia, MB; Johnston, AR; McQueen, DS | 1 |
| Aibara, K; Akaike, N; Itabashi, S; Sasaki, H | 1 |
| Büttner, U; Kurzan, R; Straube, A | 1 |
| Everitt, BJ; Muir, JL; Robbins, TW | 1 |
| Amabeoku, G | 1 |
| Duckles, SP; Li, YJ | 1 |
| Pencheva, N; Radomirov, R; Venkova, K | 1 |
| Cubells, JF; Makman, MH; Ndubuka, C | 1 |
| Miñano, FJ; Sancibrian, M; Serrano, JS | 1 |
| Allan, AM; Draski, LJ; Mayes, GG | 1 |
| Denbow, DM | 1 |
| Depaulis, A; Liu, Z; Marescaux, C; Vergnes, M | 1 |
| Gale, K; Maggio, R; Sohn, E | 1 |
| Heidelberger, R; Matthews, G | 1 |
| Berthelot, P; Brunet, C; Debaert, M; Flouquet, N; Luyckx, M; Vaccher, C | 1 |
| Funk, GD; Sholomenko, GN; Steeves, JD | 1 |
| Fujita, S; Kusunoki, M; Sakanoue, Y; Shoji, Y; Utsunomiya, J; Yamamura, T; Yanagi, H | 1 |
| Jodogne, C; Perikel, JJ; Tirelli, E | 1 |
| Fromm, GH; Mukawa, J; Nakata, M | 1 |
| Yazulla, S | 2 |
| Davies, M; Wood, JD | 1 |
| Carbone, S; Moguilevsky, JA; Rondina, D; Szwarcfarb, B | 1 |
| Baker, RE; Bingmann, D; Ruijter, JM; Speckmann, EJ; Straub, H; Walden, J | 1 |
| Bacon, E; de Barry, J; Girard, C; Gombos, G | 1 |
| Gautam, SK; Kulkarni, SK | 1 |
| Malinowska, B; Molderings, G; Schlicker, E; Schneider, D | 1 |
| Lee, MH; Strahlendorf, HK; Strahlendorf, JC | 1 |
| Collewijn, H; Pompeiano, O; van Neerven, J | 1 |
| Iarkov, AV; Kovalev, GI; Vorob'ev, VV | 1 |
| Bovolin, P; Costa, E; Grayson, DR; Memo, M | 1 |
| Shreve, PE; Uretsky, NJ | 2 |
| Corbett, R; Cornfeldt, M; Dunn, RW; Fielding, S | 1 |
| Ichihara, K; Kameyama, T; Nabeshima, T; Tohyama, K | 1 |
| Boelen, MK; Chubb, IW; Dowton, M; Morgan, IG; Wellard, J | 1 |
| Aceves, J; Arias-Montaño, JA; Martínez-Fong, D | 1 |
| Bowman, JW; Lee, BL; Thompson, DP; Whaley, HA | 1 |
| Airaksinen, MM; MacDonald, E; Rägo, L; Saano, V | 1 |
| Klockgether, T; Schwartz, M; Sontag, KH; Turski, L; Turski, WA | 1 |
| Hayashi, J; Kawasaki, S; Nakagawa, M; Nakata, T; Oguro, M; Sasaki, S; Takeda, K | 1 |
| Dohi, T; Kitayama, S; Morita, K; Tsujimoto, A | 2 |
| Allen, TG; Burnstock, G | 1 |
| Hablitz, JJ; Mistry, DK | 1 |
| Barker, JL; Lange, GD; Mandler, RN; Novotny, EA; Schaffner, AE; Smith, SV | 1 |
| Akaike, N; Ikemoto, Y; Kits, KS; Oyama, Y | 1 |
| Lothman, EW; Stringer, JL | 1 |
| de Costa, BR; Lewin, AH; Moody, EJ; Rice, KC; Skolnick, P | 1 |
| Cuenca, N; Dekorver, L; Kolb, H | 1 |
| Niles, L | 1 |
| Akaike, N; Shirasaki, T; Yakushiji, T | 1 |
| Couture, R; De Champlain, J; Hasséssian, H; Prat, A | 1 |
| Martin, DL; Rimvall, K | 1 |
| Acs, Z; Makara, GB; Zsom, L | 1 |
| Uretsky, NJ; Wallace, LJ | 1 |
| Grieve, KL; Sillito, AM | 2 |
| Ekström, P; Meissl, H | 1 |
| Deng, L; Nielsen, M; Olsen, RW | 1 |
| Cano, J; Machado, A; Ruano, D; Vitorica, J | 1 |
| Cohn, JA; Edgar, PP; Heuschneider, G; Schwartz, RD | 1 |
| Burt, DR; Huganir, RL; Kofuji, P; Mei, L; Moss, SJ; Ravindran, A; Wang, JB | 1 |
| Beyer, C; Feder, HH; Fiber, JM; Komisaruk, BR; López-Colomé, AM; Masters, DB; McCarthy, MM | 1 |
| Kubota, K; Matsumura, M; Oishi, T; Sawaguchi, T; Ueki, K | 1 |
| Ammassari-Teule, M; Castellano, C; McGaugh, JL; Pavone, F | 1 |
| Bochna, GS; Boharski, MG; Carr, TA; Eagan, PE; Harty, RF; Lassiter, DC; Markin, RS; Pour, MP; Rings, M; Schafer, DF | 1 |
| Balcar, VJ | 1 |
| Higuchi, T; Kato, N; Minatogawa, Y; Nagaki, S | 1 |
| Albers, HE; Liou, SY; Shibata, S; Ueki, S | 1 |
| Giridhar, J; Isom, GE; Peoples, RW | 1 |
| Kotak, VC; Page, CH | 1 |
| Akaike, N; Nakagawa, T; Nakaye, T; Shirasaki, T; Wakamori, M | 1 |
| Dudchenko, P; Sarter, M | 1 |
| Blankenship, K; Massey, SC; Mills, SL | 1 |
| Holder, A; Kehl, H | 1 |
| Andrioli, GC; Bonanno, G; Raiteri, M; Ruelle, A | 1 |
| Bray, GA; Tsujii, S | 1 |
| Amalric, M; Dormont, JF; Farin, D; Schmied, A | 2 |
| Hösli, E; Hösli, L; Redle, S; Rojas, J; Schramek, H | 1 |
| Korpi, ER; Oja, SS; Saransaari, P | 1 |
| James, MD; Leigh, AJ; Wilson, CA | 1 |
| Depaulis, A; Kempf, E; Liu, Z; Marescaux, C; Vergnes, M | 1 |
| Farb, DH; Farrant, M; Roca, DJ; Rozenberg, I | 1 |
| Giros, B; Llorens-Cortes, C; Quach, TT; Schwartz, JC | 1 |
| Bonanno, G; Giralt, MT; Raiteri, M | 1 |
| Bernardini, MC; Blandizzi, C; Del Tacca, M | 2 |
| Catt, KJ; Stojilković, SS; Virmani, MA | 1 |
| Bagust, J; Gardner, CR; Hussain, S; Walker, RJ; Ward, RA | 1 |
| Dodd, PR; Gundlach, AL; Harper, PA; Johnston, GA; Lummis, SC | 1 |
| Kohlenbach, A; Schlicker, E | 1 |
| Breese, GR; Givens, BS | 1 |
| Kim, KH; Takeuchi, H | 1 |
| Pericić, D; Tvrdeić, A | 1 |
| Blakeman, DP; Davis, JP; Im, WB | 1 |
| Bhisitkul, RB; Gordon, TR; Kocsis, JD; Waxman, SG | 1 |
| Baumann, PA; Waldmeier, PC | 1 |
| Barnard, EA; Devine, J; Macdonald, RL; Moss, SJ; Nayeem, N; Porter, NM; Smart, TG; Stephenson, FA | 1 |
| Hayashi, Y; Yajima, Y | 2 |
| Michler, A | 1 |
| Sved, AF; Sved, JC | 1 |
| Ito, S; Negishi, M | 1 |
| Baldwin, BA; De La Riva, C; Ebenezer, IS | 1 |
| Cheun, JE; Lee, MB; Yeh, HH | 1 |
| Akema, T; Chiba, A; Kimura, F | 1 |
| Hicks, TP; Kaneko, T | 1 |
| Mangat, HK; Rattan, AK | 3 |
| Cardinali, DP; Chuluyan, HE; Rosenstein, RE | 1 |
| Brioni, JD; Decker, MW; Gamboa, LP; Izquierdo, I; McGaugh, JL | 1 |
| Biswas, S; Poddar, MK | 2 |
| Jones, TA; Lindner, MD; Schallert, T | 1 |
| Kostowski, W; Pałejko, W; Plaznik, A; Stefański, R | 1 |
| Slater, NT; Smith, RD; Turek, FW | 1 |
| Ebert, U; Krnjević, K | 1 |
| Dhatt, RK; Mangat, HK; Rattan, AK | 3 |
| Hofmann, HD; Huba, R | 1 |
| Fukuda, H; Hirayama, T; Ono, H | 1 |
| Feder, HH; Malik, KF; McCarthy, MM | 1 |
| Shaikh, MB; Siegel, A | 1 |
| Itoh, J; Kameyama, T; Nabeshima, T; Noda, Y; Tohyama, K | 1 |
| Bisset, GW; Chowdrey, HS; Fairhall, KM; Gunn, LK | 1 |
| Taniyama, K | 1 |
| Alho, H; Costa, E; Ferrero, P; Guidotti, A; Santi, MR; Vicini, S | 1 |
| Hendrickson, A; Noble, B; Ryan, M; Wu, JY | 1 |
| Cañadas, S; Giménez, A; González, MP; Sánchez, C | 1 |
| Paul, SM; Schwartz, RD; Suzdak, PD | 1 |
| Ganten, D; Lang, RE; Schneider, B; Unger, T | 1 |
| Akagi, H; Yanagisawa, M | 1 |
| Crema, A; Manzo, L; Onori, L; Perucca, E; Rizzi, CA; Tonini, M | 1 |
| Inenaga, K; Mason, WT | 1 |
| Akaike, N; Ikemoto, Y; Kijima, H | 1 |
| Cervoni, P; Lai, FM; Tanikella, T | 1 |
| Heuschneider, G; Schwartz, RD | 1 |
| Ovtcharov, R; Yakimova, K | 1 |
| Bleck, V; Harris, RA; Lewin, E; Peris, J; Zahniser, NR | 1 |
| Fukuda, H; Matsumoto, K; Ono, H; Yamazaki, J | 1 |
| Allan, AM; Harris, RA; Spuhler, KP | 1 |
| Bereiter, DA; Gann, DS | 1 |
| Moshé, SL; Sharpless, NS; Sperber, EF; Wurpel, JN | 1 |
| Dudek, BC; Phillips, TJ | 1 |
| Aley, KO; Kulkarni, SK | 1 |
| Besson, MJ; Caboche, J; Le Saux, F; Maurin, Y; Mitrovic, N; Sauter, A | 1 |
| Amenta, F; Erdö, SL; Mione, MC; Wolff, JR | 1 |
| Andrioli, GC; Asaro, D; Bonanno, G; Cavazzani, P; Pellegrini, G; Raiteri, M | 1 |
| Biggio, G; Cau, A; Corda, MG; Laudani, U; Longoni, B; Paci, S; Salvadori, S | 1 |
| Gähwiler, BH; Thompson, SM | 1 |
| Giuliani, S; Maggi, CA; Manzini, S; Meli, A | 1 |
| Biggio, G; Concas, A; Corda, MG; Serra, M | 1 |
| Masotto, C; Negro-Vilar, A; Wisniewski, G | 1 |
| Enjalbert, A; Kordon, C; Lechat, P; Lloyd, KG; Paillard, JJ; Thuret, F; Vincens, M | 1 |
| Bonanno, G; Fedele, E; Raiteri, M | 1 |
| Bell, RD; Frey, JM; Huffman, RD; Ticku, MK | 1 |
| Amenta, F; Erdö, SL; Ezer, E; Matuz, J; Wolff, JR | 1 |
| Blakeman, DP; Davis, JP; Im, WB; Tai, MM | 1 |
| Blasquez, C; Delbende, C; Jégou, S; Tranchand-Bunel, D; Vaudry, H | 1 |
| Depaulis, A; Marescaux, C; Snead, OC; Vergnes, M | 1 |
| Guthrie, GD; Nicholson-Guthrie, CS | 1 |
| Harro, J; Kiivet, RA; Pŏld, M; Rägo, L | 1 |
| Bowen, DM; Cross, AJ; Francis, PT; Green, AR; Robinson, TN; Stirling, JM | 1 |
| Ikawa, K; Kariya, T; Motohashi, N | 1 |
| Georgiev, V; Kambourova, T; Yonkov, D | 1 |
| Baumann, PA; Feldtrauer, JJ; Waldmeier, PC; Wicki, P | 2 |
| Cash, DJ; Subbarao, K | 1 |
| Bonanno, G; Cantoni, C; Pellegrini, G; Raiteri, M | 1 |
| Kostowski, W; Płaźnik, A; Stefański, R | 1 |
| Gal'chenko, AA; Iarkov, AV; Kovalev, GI; Vorob'ev, VV | 1 |
| Karlsson, G; Olpe, HR | 1 |
| Bédard, L; Roberge, AG; Seoane, JR; Thibault, L; Wandji, SA | 1 |
| Malchow, RP; Qian, HH; Ripps, H | 1 |
| McCormick, DA | 1 |
| Akaike, N; Hattori, K; Inomata, N; Oomura, Y | 1 |
| Samochocki, M; Strosznajder, J | 2 |
| Bingmann, D; Speckmann, EJ; Walden, J | 1 |
| Di Scala, G; Sandner, G | 1 |
| Amalric, M; Koob, GF | 1 |
| Hikosaka, O; Sakamoto, M | 1 |
| Nagaya, H; Negishi, N; Okada, R | 1 |
| Allan, AM; Buck, KJ; Harris, RA | 1 |
| Pan, ZZ; Williams, JT | 1 |
| Bauer, RM; Waldrop, TG | 1 |
| Kontro, P; Oja, SS | 1 |
| Castellano, C; Introini-Collison, IB; McGaugh, JL; Pavone, F | 1 |
| Rosenberg, HC; Tietz, EI; Zhang, H | 1 |
| Barat, A; Marsal, J; Ramírez, G; Solsona, C | 1 |
| DiMicco, JA; Lisa, M; Marmo, E; Wible, JH | 1 |
| Brioni, JD; McGaugh, JL; Nagahara, AH | 1 |
| Carter, DA; Lightman, SL; Saridaki, E | 1 |
| Hashimoto, T; Kimori, M; Kuriyama, K; Nakamura, Y | 1 |
| Amatsu, M; Okada, Y; Yamauchi, R | 1 |
| Austin, MC; Kalivas, PW | 1 |
| Krsiak, M | 1 |
| Nistri, A; Sivilotti, L | 2 |
| Höglund, U; Magnusson, A; Sjöquist, M | 1 |
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| Neal, MJ; Shah, MA | 1 |
| Mize, RR; White, DA | 1 |
| Jeffery, D; Lunt, GG; Rutherford, DM; Weitzman, PD | 1 |
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| Mehta, AK; Ticku, MK | 1 |
| Löscher, W; Schwark, WS | 2 |
| Rosenberg, HC; Tietz, EI | 1 |
| Cox, DH; Guidotti, A; Santi, MR | 1 |
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| Cañadas, S; Castro, E; Gimenez, G; González, MP; Oset-Gasque, MJ | 1 |
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| Budelli, R; González-Estrada, MT; Soto, E; Vega, R | 1 |
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| Acs, Z; Kapócs, G; Makara, GB; Szabó, B | 1 |
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| Biggio, G; Concas, A; Mele, S | 1 |
| Ong, J | 1 |
| Cools, A; Gelissen, M | 1 |
| Cazalets, JR; Cournil, I; Geffard, M; Moulins, M | 1 |
| Randle, JC; Renaud, LP | 1 |
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| Ball, AK; Brandon, C | 1 |
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| Moshe, SL; Okada, R; Sperber, EF; Wong, BY; Zhao, DY | 1 |
| Kaneko, A; Tachibana, M | 1 |
| Davidson, W; Rice, MA; Robinson, SE | 1 |
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| Itoh, Y; Nishibori, M; Oishi, R; Saeki, K | 1 |
| Fukuda, H; Kasuya, M; Matsumoto, K; Yamazaki, J | 1 |
| Miller, JA; Richter, JA | 1 |
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| Reis, DJ; Saji, M | 1 |
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| Abshire, VM; DiMicco, JA | 1 |
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| Burnside, B; Dearry, A | 1 |
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| Cherniack, NS; Haxhiu, MA; Mitra, J; Prabhakar, NR; van Lunteren, E | 1 |
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| Apud, JA; Casanueva, F; Cocchi, D; Iuliano, E; Locatelli, V; Müller, EE; Racagni, G | 1 |
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| Fujiwara, H; Hanada, S; Ichikawa, K; Mita, T; Nishino, N; Noguchi-Kuno, SA; Tanaka, C | 1 |
| Kamp, CW; Morgan, WW | 2 |
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| Hirsch, JD | 1 |
| Christensen, AV; Scheel-Krüger, J | 1 |
| Costa, E | 1 |
| Hösli, E; Hösli, L; Möhler, H; Richards, JG | 1 |
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| Collins, JF; Karobath, M; Mannonen, A; Supavilai, P | 1 |
| Forchetti, MC; Guidotti, A; Krogsgaard-Larsen, P; Moroni, F | 1 |
| Lamm, MC; Russell, VA; Taljaard, JJ | 1 |
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| Artaud, F; Bourgoin, S; Glowinski, J; Montsatruc, JL; Reisine, T; Soubrié, P | 1 |
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| Brown, DA; Scholfield, CN | 1 |
| Barker, JL; Huang, A; Ticku, MK | 1 |
| Degener, P; Krause, DN; Roberts, E; Wong, E | 1 |
| Gale, K; Iadarola, MJ | 3 |
| Edvinsson, L; Larsson, B; Skärby, T | 1 |
| Hösli, E; Hösli, L | 2 |
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| Risley, EA; Totaro, JA; Williams, M | 1 |
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| Dichter, M; Snodgrass, SR; White, WF | 1 |
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| Cananzi, AR; Costa, E; Guidotti, A | 1 |
| DeFeudis, FV; Devilliers, G; Mandel, P; Sarliéve, LL; Varga, V | 1 |
| Krogsgaard-Larsen, P | 1 |
| Fletcher, A; James, TA; Kilpatrick, IC; MacLeod, NK; Starr, MS | 1 |
| James, TA; Kilpatrick, IC; MacLeod, NK; Starr, MS | 2 |
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| Lester, BR; Miller, AL; Peck, EJ | 1 |
| Matus, A; Pehling, G; Wilkinson, D | 1 |
| Smith, JA; Tunnicliff, G | 1 |
| Brennan, MJ; Cantrill, RC; Krogsgaard-Larsen, P; Oldfield, M | 1 |
| Biggio, G; Concas, A; Corda, MG; Guarneri, P | 1 |
| Besser, GM; Delitala, G; Grossman, A; Yeo, T | 1 |
| Gardell, MA; Neale, JH; Shibla, DB | 1 |
| Barker, JL; Mathers, DA | 1 |
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| Krause, DN; Mori, A; Roberts, E; Wong, E | 1 |
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| Asano, T; Ogasawara, N | 1 |
| Marangos, PJ; Martino, AM | 1 |
| Falch, E; Krogsgaard-Larsen, P | 1 |
| Gillis, RA; Hamosh, P; Yamada, KA | 1 |
| Mitchell, CK; Redburn, DA | 1 |
| Biggio, G; Concas, A; Corda, MG; Corongiu, FP; Guarneri, P; Rossetti, Z | 1 |
| Kuhar, MJ; Palacios, JM | 1 |
| Braestrup, C; Nielsen, M | 1 |
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| Cavagnini, F; Grandison, L; Guidotti, A; Invitti, SC; Schmid, R | 1 |
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| Barker, JL; Jackson, MB; Lecar, H; Mathers, DA | 1 |
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| Bichard, AR; Little, HJ | 1 |
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| Frere, RC; Macdonald, RL; Young, AB | 1 |
| Curtis, DR; Hjeds, H; Krogsgaard-Larsen, P; Leah, JD; Peet, MJ | 1 |
| Cagan, RH; Quinn, MR | 1 |
| Ben-Ari, Y; Cherubini, E; Padjen, A; Rovira, C | 1 |
| Kolasiewicz, W; Schwarz, M; Sontag, KH; Wand, P | 1 |
| Gillis, RA; Hamosh, P; Norman, WP; Yamada, KA | 1 |
| Dutton, GR; Freedman, EG; Pearce, BR | 1 |
| Gardner, CR; Piper, DC | 1 |
| Armstrong, DR; Breckenridge, RJ; Suckling, CJ | 1 |
| Barnard, EA; Mamalaki, C; Sigel, E | 1 |
| Breese, GR; Frye, GD | 1 |
| Richard, J; Wood, PL | 1 |
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| Asano, T; Ogasawara, N; Yamada, Y | 1 |
| Auslander, D; Davidoff, RA; Grayson, V; Hackman, JC | 1 |
| Cools, AR; Jaspers, R; Kolasiewicz, W; Sontag, KH; Wolfarth, S | 1 |
| Smokcum, RW | 1 |
| Patel, SC; Peck, EJ | 1 |
| Erdö, SL; Lapis, E | 1 |
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| Ho, IK; Hoskins, B; Lim, DK; Norris, JC; Sivam, SP | 1 |
| Giotti, A; Luzzi, S; Spagnesi, S; Zilletti, L | 1 |
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| Frey, KA; Pan, HS; Penney, JB; Young, AB | 1 |
| Corda, MG; Guidotti, A | 1 |
| Rägo, LK; Zarkovsky, AM | 1 |
| Kilbinger, H; Kleinrok, A | 1 |
| Breese, GR; Frye, GD; McCown, TJ | 1 |
| Gallagher, JP; Nakamura, J; Shinnick-Gallagher, P | 1 |
| Madtes, P; Redburn, DA | 1 |
| Riley, M; Scholfield, CN | 1 |
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| Lucacchini, A; Martini, C; Rigacci, T | 1 |
| Mitchell, R; Wilson, LE | 1 |
| Johnston, GA; Skerritt, JH | 1 |
| Huffman, RD; Ticku, MK | 1 |
| Curtis, DR; Falch, E; Krogsgaard-Larsen, P; Leah, JD; Peet, MJ | 1 |
| Apud, JA; Cocchi, D; Iuliano, E; Locatelli, V; Müller, EE; Racagni, G | 1 |
| Adamec, R; Racine, RJ; Tuff, LP | 1 |
| Mishra, RK; Racine, RJ; Tuff, LP | 1 |
| Deisz, RA; Dose, M | 1 |
| Quinn, MR; Somerville, RA | 1 |
| Enna, SJ; Gallagher, JP | 1 |
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| Mallick, BN; Pal, D | 1 |
| Caleo, M; Cerri, C; Gianfranceschi, L; Maffei, L; Pietrasanta, M; Restani, L | 1 |
| Baptiste, SL; Devinsky, O; French, JA; Kuzniecky, RI; Ludvig, N; Tang, HM | 1 |
| Aragona, BJ; Carelli, RM; Day, JJ; Jones, JL; Wheeler, RA; Wightman, RM | 1 |
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| Blumberg, MS; Marcano-Reik, AJ; Prasad, T; Weiner, JA | 1 |
| Dong, YX; Hou, Y; Sun, JY; Wang, F; Wu, CF; Yang, JY | 1 |
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| Kim, YS; Lee, IO; Lim, ES; Son, JK | 1 |
| Dabbish, NS; Raizen, DM | 1 |
| Augustin, M; Pogatzki-Zahn, EM; Reichl, S; Zahn, PK | 1 |
| Kitamura, N; Shibuya, I; Shinohara, H; Takahashi, K; Yamanaka, Y | 1 |
| Carlen, PL; Florez, CM; Koifman, J; Shin, DS; Valiante, TA; Ye, H; Zhang, L; Zhang, ZJ | 1 |
| Hanafusa, N; Kawasaki, H; Okamoto, K; Takatori, S | 1 |
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| Gao, J; Jia, Y; Jiang, Y; Yan, L; Yang, G; Yu, J | 1 |
| de Araújo, DB; Fernandes, A; Foresti, ML; Garcia-Cairasco, N; Marroni, SS; Rodrigues, MC; Romcy-Pereira, RN; Rossetti, F | 1 |
| Khakpai, F; Nasehi, M; Yousefi, B; Zarrindast, MR | 1 |
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| French, AS; Meisner, S; Pfeiffer, K; Torkkeli, PH | 1 |
| Accardi, MV; Brown, DD; Forrester, SG; Siddiqui, SZ | 1 |
| Abe, M; Egashira, N; Fujiwara, M; Iwasaki, K; Mishima, K; Niki, T; Oishi, R; Shirakawa, A | 1 |
| Dai, XY; Hao, YJ; Li, YX; Liu, HY; Sun, T; Wang, HY; Yu, JQ | 1 |
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| Cui, N; Jiang, C; Jin, X; Jin, XT; Zhong, W | 1 |
| Mabey, JK; Shin, SI; Steffensen, SC; Ting-A-Kee, R; van der Kooy, D; Vargas-Perez, H | 1 |
| Cebada, J; Cortes, C; Flores, A; Galicia, S; Galindo, F | 1 |
| Cao, D; Gussin, HA; Pepperberg, DR; Qian, H; Rosenthal, SJ; Tomlinson, ID | 1 |
| Albrechet-Souza, L; Almada, RC; Brandão, ML | 1 |
| Nobre, MJ | 1 |
| Chapalain, A; Chevalier, S; Dagorn, A; Duclairoir-Poc, C; Feuilloley, MG; Hillion, M; Mijouin, L; Orange, N; Taupin, L | 1 |
| Han, JY; Hong, JT; Lee, CI; Oh, KW | 1 |
| Mueller, U; Raccuglia, D | 1 |
| Grauer, M; Jabs, R; Passlick, S; Schäfer, C; Seifert, G; Steinhäuser, C | 1 |
| Atkinson, MA; Chen, Z; Dang, H; Guan, A; Jin, Y; Kaufman, DL; Tian, J | 1 |
| Chavan, JG; Salunke, BP; Umathe, SN | 1 |
| Coutinho, MR; Ferreira, MD; Menescal-de-Oliveira, L; Zugaib, J | 1 |
| Dietz, B; Milenkovic, I; Nerlich, J; Reinert, T; Rübsamen, R; Witte, M | 1 |
| Abreu, AR; Chianca, DA; da Silva, LG; de Abreu, AR; de Menezes, RC; de Souza, AA; Santos, LT | 1 |
| Cairns, BE; Dong, XD; Somvanshi, RK; Song, E; Tan, SN | 1 |
| De Vries, TJ; Lubbers, BR; Schetters, D; Smit, AB; Spijker, S; van Mourik, Y | 1 |
| Denman, RB; Merz, G; Sung, YJ; Xie, W | 1 |
| Ferreira, MD; Menescal-de-Oliveira, L | 1 |
| Bairam, A; Delhaes, F; Fournier, S; Kinkead, R; Peyter, AC; Tolsa, JF | 1 |
| Melloni, RH; Morrison, TR; Ricci, LA | 1 |
| Bilican, B; Burr, K; Chandran, S; Dando, O; Haghi, G; Hardingham, GE; James, OT; Kind, PC; Livesey, MR; Qiu, J; Rajan, R; Wyllie, DJ | 1 |
| Glinka, Y; Hasilo, C; Paraskevas, S; Prud'homme, GJ; Udovyk, O; Wang, Q | 1 |
| Hsieh, YC; Puche, AC | 1 |
| Almada, RC; Brandão, ML; Coimbra, NC | 1 |
| Auger, ML; Floresco, SB | 1 |
| Fu, J; Gu, J; Gu, Y; Li, G; Ran, R; Wang, L; Wang, Q; Zhang, A; Zhao, Y; Zhong, H | 1 |
| Bellemer, A; Han, B; Koelle, MR | 1 |
| Bojar, M; Chudomel, O; Galanopoulou, AS; Hasson, H; Moshé, SL | 1 |
| Pavlova, IV; Rysakova, MP | 1 |
| Imamura, Y; Iwata, K; Kita, K; Kobayashi, M; Nakaya, Y; Okada-Ogawa, A; Sessle, BJ; Shinoda, M | 1 |
| Abdallah, K; Artola, A; Dallel, R; Luccarini, P; Monconduit, L | 1 |
| Pierobon, P | 1 |
| Baldo, BA; Mena, JD; Sadeghian, K; Spencer, RC | 1 |
| Bose, J; Conn, V; Domingos, P; Feijó, JA; Gilliham, M; Kaur, S; Ramesh, SA; Ryan, PR; Shabala, S; Tyerman, SD; Ullah, S; Wege, S; Xu, B | 1 |
| Hatam, M; Nasimi, A; Rasoulpanah, M | 1 |
| Barson, JR; Leibowitz, SF | 1 |
| Miranda, MI; Rodríguez-García, G | 1 |
| Cabral, A; Perello, M; Portiansky, E; Sánchez-Jaramillo, E; Zigman, JM | 1 |
| Gao, Y; Kosten, T; Li, DP; Zhou, JJ; Zhu, Y | 1 |
| Hirose, N; Kamei, J; Saitoh, A | 1 |
| Cho, CB; Lee, YJ; Moon, HC; Park, YS | 1 |
| Garraway, SM; Grau, JW; Huang, YJ; Lee, KH; Murphy, L | 1 |
| Vargas, RA | 1 |
| Li, J; Liu, C; Lu, WY; Wang, S; Xiang, YY; Yi, F; Zhu, J | 1 |
| Cai, J; Chen, RX; Liao, FF; Liu, FY; Wan, Y; Wang, J; Xu, FQ; Yi, M; Zhang, C; Zhang, Y | 1 |
| Feng, AL; Feng, Q; Gui, L; Kaltsidis, G; Lu, WY; Xiang, YY | 1 |
| Chen, L; Chen, T; Yang, R; Zhang, B; Zhang, S | 1 |
| Antoni, FA; Barkóczy, J; Belelli, D; Brown, AR; Etherington, LA; Gacsályi, I; Gunn, BG; Kertész, S; Lambert, JJ; Ling, I; Livesey, MR; Mihalik, B; Monteiro, O; Pallagi, K; Pálvölgyi, A; Spedding, M; Varga, P | 1 |
| Acerbo, MJ; Lazareva, OF | 1 |
| Bolser, DC; Jakus, J; Kotmanova, Z; Martvon, L; Misek, J; Musselwhite, MN; Pitts, T; Poliacek, I; Shen, TY; Simera, M; Veternik, M | 1 |
| Biscocho, D; Cook, JG; Leise, EM; Long, J; Shah, N | 1 |
| Derbenev, AV; Gao, H; Heesch, CM; Korim, WS; Yao, ST | 1 |
| Bocian, R; Broncel, A; Konopacki, J; Kłos-Wojtczak, P | 1 |
| Gilliham, M; Long, Y; Tyerman, SD | 1 |
| Ardianto, C; Ikeda, H; Kamei, J; Ueda, D; Yonemochi, N | 1 |
| Barandov, A; Bricault, S; DeTienne, E; Hai, A; Harvey, P; Jasanoff, A | 1 |
| Labrada-Moncada, FE; Martínez-Torres, A; Reyes-Haro, D | 1 |
| Hanamoto, H; Kudo, C; Maegawa, H; Niwa, H; Usami, N | 1 |
| Anunu, R; Richter-Levin, G; Vouimba, RM | 1 |
| Baracz, SJ; Cornish, JL; Everett, NA; Green, TA; Robinson, KJ | 1 |
| Goodpaster, C; Leuner, B; Maurer, S; Sabihi, S | 1 |
| Fu, B; Liu, C; Luo, T; Shi, F; Yu, S; Yu, T; Zhang, L; Zhang, Y | 1 |
| Chen, J; Hasanein, P; Komaki, A; Yari, S | 1 |
| Axelsson, SFA; Horiguchi, N; Horst, NK; Robbins, TW; Roberts, AC | 1 |
| Auger, A; Baldo, BA; Diaz, JC; Dunaway, K; Sadeghian, K; Sheil, E | 1 |
| Hayashi, H; Ihara, M; Kai, K; Matsuda, K; Tanaka, K | 1 |
| Alaei, H; Amohashemi, E; Reisi, P | 1 |
| Mallick, BN; Mishra, Y | 1 |
| Aikins, AO; Cunningham, JT; Farmer, GE; Little, JT | 1 |
| Anderson, MJ; den Hartigh, AB; Fink, SL; Frølund, B; Loomis, WP | 1 |
| Cruces, W; Docampo-Palacios, ML; Okhovat, A; Ramirez, GA; Ray, KP | 1 |
59 review(s) available for muscimol and gamma-aminobutyric acid
| Article | Year |
|---|---|
The role of receptor binding in drug discovery.
Topics: Animals; Drug Design; Humans; Receptors, Drug | 1993 |
GABA-Activated ligand gated ion channels: medicinal chemistry and molecular biology.
Topics: Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Ion Channels; Ligands; Receptors, GABA; Receptors, GABA-A; Structure-Activity Relationship | 2000 |
Involvement of GABA in the actions of neuropsychotropic drugs.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Barbiturates; Benzodiazepines; Cats; Cerebellar Cortex; Cerebral Cortex; gamma-Aminobutyric Acid; Hippocampus; Hypnotics and Sedatives; Muscimol; Muscle Relaxants, Central; Psychotropic Drugs; Purkinje Cells; Rats; Spinal Cord; Substantia Nigra; Vestibular Nucleus, Lateral | 1979 |
Inhibitory mechanisms in the substantia nigra and the dopamine pathway.
Topics: Amino Acids; Amino Acids, Cyclic; Animals; Brain Mapping; Cats; Corpus Striatum; Cyclohexanecarboxylic Acids; Dopamine; Electrophysiology; Ethanolamines; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Homovanillic Acid; Hydroxydopamines; Mice; Motor Activity; Muscimol; Neural Inhibition; Neural Pathways; Oxidopamine; Picrotoxin; Rats; Substantia Nigra | 1979 |
Mechanism of action of benzodiazepines - the GABA hypothesis.
Topics: Acetylcholine; Animals; Benzodiazepines; Brain; Catecholamines; Cerebellum; Diazepam; gamma-Aminobutyric Acid; Ganglia, Autonomic; Glutamates; Glycine; Guanosine Monophosphate; Humans; Muscimol; Neurons; Receptors, Neurotransmitter; Serotonin | 1978 |
GABA receptor agonists: relationship between structure and biological activity in vivo and in vitro.
Topics: Animals; gamma-Aminobutyric Acid; Kinetics; Muscimol; Oxazoles; Receptors, Drug; Structure-Activity Relationship; Substantia Nigra | 1979 |
Behavioural consequences of manipulating GABA neurotransmission in the superior colliculus.
Topics: Animals; Bicuculline; Electrophysiology; gamma-Aminobutyric Acid; Motor Activity; Muscimol; Neurons, Afferent; Neurons, Efferent; Picrotoxin; Rats; Superior Colliculi; Synaptic Transmission | 1992 |
GABA and epilepsy: basic concepts from preclinical research.
Topics: Aminocaproates; Animals; Anticonvulsants; Brain; Epilepsy; gamma-Aminobutyric Acid; Humans; Muscimol; Rats; Receptors, GABA-A; Synaptic Transmission; Vigabatrin | 1992 |
Sensitivities of Achatina giant neurones to putative amino acid neurotransmitters.
Topics: Animals; Baclofen; Electric Conductivity; gamma-Aminobutyric Acid; Membrane Potentials; Muscimol; Neurons; Neurotransmitter Agents; Receptors, GABA-A; Receptors, GABA-B; Snails | 1992 |
Effect of GABAergic and glutamatergic drugs injected into the ventral pallidum on locomotor activity.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamine; Animals; gamma-Aminobutyric Acid; Globus Pallidus; Glutamates; Ibotenic Acid; Kainic Acid; Motor Activity; Muscimol; N-Methylaspartate; Picrotoxin | 1991 |
Presynaptic GABA receptors.
Topics: Animals; Baclofen; Bicuculline; Brain; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Homeostasis; Muscimol; Receptors, GABA-A; Receptors, Neurotransmitter; Tissue Distribution | 1990 |
Multilevel transneuronal degeneration after brain damage. Behavioral events and effects of anticonvulsant gamma-aminobutyric acid-related drugs.
Topics: Animals; Atrophy; Behavior, Animal; Cerebrovascular Disorders; Corpus Striatum; Diazepam; gamma-Aminobutyric Acid; Muscimol; Neural Pathways; Neurons; Rats; Substantia Nigra; Thalamus | 1990 |
[GABAergic neurons in the mammalian intestine].
Topics: Animals; Autonomic Fibers, Postganglionic; Autoradiography; Baclofen; Calcium; Digestive System; gamma-Aminobutyric Acid; Gastrointestinal Motility; Glutamate Decarboxylase; Guinea Pigs; Histocytochemistry; Humans; In Vitro Techniques; Muscimol; Myenteric Plexus; Potassium; Rabbits; Rats; Receptors, GABA-A; Substance P; Synaptic Transmission; Vasoactive Intestinal Peptide | 1985 |
[GABA and central regulation of cardiovascular function].
Topics: Angiotensin II; Animals; Anti-Anxiety Agents; Antihypertensive Agents; Baclofen; Benzodiazepines; Bicuculline; Blood Pressure; Brain Mapping; Cardiovascular Physiological Phenomena; Cardiovascular System; Cats; Central Nervous System; gamma-Aminobutyric Acid; Heart Rate; Hypertension; Muscimol; Rabbits; Reflex; Reticular Formation; Synaptic Transmission; Vasomotor System; Vasopressins | 1985 |
[Implications of GABAergic synapses in neuropsychiatry].
Topics: 4-Aminobutyrate Transaminase; Animals; Anti-Anxiety Agents; Anticonvulsants; Antidepressive Agents; Anxiety; Brain; Cats; Cerebral Cortex; Depressive Disorder; Disease Models, Animal; Dyskinesia, Drug-Induced; Epilepsy; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Haplorhini; Humans; Mental Disorders; Muscimol; Receptors, GABA-A; Seizures; Synapses; Synaptic Transmission | 1985 |
Drugs acting on amino acid neurotransmitters.
Topics: Acoustic Stimulation; Amino Acids; Animals; Chemical Phenomena; Chemistry; Diazepam; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Humans; Hypoxia; Imidazoles; Isoxazoles; Mice; Mice, Inbred DBA; Muscimol; Myoclonus; Neurotransmitter Agents; Papio; Rats; Rats, Inbred Strains; Seizures; Valproic Acid | 1986 |
Neurochemical stratification in the inner plexiform layer of the vertebrate retina.
Topics: Acetylcholine; Animals; Autoradiography; Cats; Columbidae; Dopamine; Fishes; gamma-Aminobutyric Acid; Glycine; Humans; Muscimol; Neurons; Neurotransmitter Agents; Peptides; Rabbits; Rats; Retina; Retinal Ganglion Cells; Serotonin; Turtles | 1986 |
[GABA receptors in the central nervous system. Biochemical and pharmacological aspects].
Topics: Allosteric Site; Animals; Anti-Anxiety Agents; Barbiturates; Benzodiazepines; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; gamma-Aminobutyric Acid; Humans; Muscimol; Picrotoxin; Receptors, GABA-A | 1987 |
Mechanisms of seizure control mediated by gamma-aminobutyric acid: role of the substantia nigra.
Topics: Animals; Bicuculline; Cell Compartmentation; Epilepsy; gamma-Aminobutyric Acid; Microinjections; Morphine; Muscimol; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Seizures; Substantia Nigra | 1985 |
The pharmacology of myoclonus.
Topics: 5-Hydroxytryptophan; Adrenocorticotropic Hormone; Animals; Anticonvulsants; Benzodiazepines; Brain; Disease Models, Animal; gamma-Aminobutyric Acid; Guinea Pigs; Humans; Levodopa; Muscimol; Myoclonus; Narcotics; Papio; Receptors, GABA-A; Receptors, Opioid; Receptors, Serotonin; Serotonin; Thyrotropin-Releasing Hormone | 1985 |
GABA in morphine analgesia and tolerance.
Topics: Analgesia; Animals; Baclofen; Benzodiazepines; Bicuculline; Brain Chemistry; Cyclohexanecarboxylic Acids; Drug Tolerance; GABA Antagonists; gamma-Aminobutyric Acid; Mice; Morphine; Muscimol; Naloxone; Picrotoxin; Rats; Receptors, GABA-A; Synaptic Transmission | 1985 |
Interaction of benzodiazepine receptor agonists and inverse agonists with the GABA benzodiazepine receptor complex.
Topics: Animals; Barbiturates; Drug Interactions; gamma-Aminobutyric Acid; Models, Biological; Muscimol; Rats; Receptors, GABA-A | 1985 |
Benzodiazepine receptors resolved.
Topics: Animals; Antibodies, Monoclonal; Autoradiography; Benzodiazepines; Benzodiazepinones; Bicuculline; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Chlorides; Clonazepam; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Histocytochemistry; Humans; Immunologic Techniques; Ionophores; Muscimol; Neurons; Radioisotopes; Radioligand Assay; Receptors, GABA-A; Spinal Cord; Synapses; Tissue Distribution | 1986 |
Heterocyclic analogues of GABA: chemistry, molecular pharmacology and therapeutic aspects.
Topics: Analgesics; Animals; Anticonvulsants; Blood-Brain Barrier; Chemical Phenomena; Chemistry; gamma-Aminobutyric Acid; Humans; Isoxazoles; Muscimol; Nipecotic Acids; Receptors, GABA-A | 1985 |
Valproate and myoclonus.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Aspartic Acid; Clonazepam; DDT; Disease Models, Animal; Flurazepam; gamma-Aminobutyric Acid; Glycine; Isoxazoles; Light; Morphine; Muscimol; Myoclonus; Serotonin; Urea; Valproic Acid | 1986 |
Role of the basal ganglia in the initiation of saccadic eye movements.
Topics: Animals; Basal Ganglia; Eye Movements; gamma-Aminobutyric Acid; Muscimol; Neurons; Oculomotor Muscles; Photic Stimulation; Saccades; Substantia Nigra; Superior Colliculi | 1986 |
The neurochemical sequelae of olfactory bulbectomy.
Topics: Acetylcholine; Animals; Aspartic Acid; Brain; Calcium; Dopamine; Epinephrine; Female; gamma-Aminobutyric Acid; Glutamates; Male; Mice; Muscimol; Norepinephrine; Olfactory Bulb; Ornithine Decarboxylase; Rats; Receptors, Muscarinic; Serotonin; Spermine; Tyrosine 3-Monooxygenase | 1980 |
Dynamic utilization of GABA in substantia nigra: regulation by dopamine and GABA in the striatum, and its clinical and behavioral implications.
Topics: 4-Aminobutyrate Transaminase; Afferent Pathways; Aminocaproates; Animals; Basal Ganglia; Behavior, Animal; Brain; Chlorpromazine; Corpus Striatum; Dopamine; Dopamine Antagonists; Dyskinesia, Drug-Induced; Efferent Pathways; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Dehydrogenase; Humans; Huntington Disease; Muscimol; Neurons; Rats; Receptors, Cell Surface; Receptors, Dopamine; Receptors, GABA-A; Schizophrenia; Serotonin; Substantia Nigra; Synapses; Synaptic Transmission; Tyrosine 3-Monooxygenase; Vigabatrin | 1981 |
Psychoactive agents and GABA-receptors.
Topics: Alcoholism; Animals; Anti-Anxiety Agents; Antipsychotic Agents; Barbiturates; Benzodiazepines; Ethanol; gamma-Aminobutyric Acid; Humans; Muscimol; Narcotics; Psychotropic Drugs; Pteridines; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Distinction of benzodiazepine receptor agonists and inverse agonists by binding studies in vitro.
Topics: Affinity Labels; Animals; Anti-Anxiety Agents; Benzodiazepines; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Etazolate; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Muscimol; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Binsing studies with muscimol; relation ty synaptic gamma-aminobutyrate receptors.
Topics: Animals; Astacoidea; Autoradiography; Blood Vessels; Brain; Cattle; Cerebellum; Culture Techniques; Freezing; gamma-Aminobutyric Acid; Kinetics; Muscimol; Muscles; Oxazoles; Pia Mater; Polyethylene Glycols; Rats; Receptors, Neurotransmitter; Sodium; Subcellular Fractions; Substrate Specificity | 1980 |
Inhibitors of the GABA uptake systems.
Topics: Animals; Astrocytes; Biological Transport; Brain; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Isoxazoles; Muscimol; Neuroglia; Neurons; Nipecotic Acids; Receptors, Neurotransmitter; Structure-Activity Relationship; Synapses; Synaptosomes | 1980 |
GABA-agonists as anti-epileptic agents.
Topics: Animals; Anticonvulsants; Barbiturates; Benzodiazepines; Disease Models, Animal; Epilepsy; Etomidate; gamma-Aminobutyric Acid; Hydroxybutyrates; Isonicotinic Acids; Mice; Muscimol; Rats; Receptors, Cell Surface; Receptors, GABA-A; Sodium Oxybate | 1981 |
GABA and benzodiazepine receptors. Studies on their localization in the hippocampus and their interaction with central dopamine neurons in the rat brain.
Topics: Animals; Brain; Dopamine; Etazolate; Flunitrazepam; gamma-Aminobutyric Acid; Glutamates; Hippocampus; Muscimol; Neural Pathways; Neurons; Neurons, Afferent; Rats; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A | 1981 |
Physiological and behavioral studies with muscimol.
Topics: Animals; Behavior; Behavior, Animal; Blood-Brain Barrier; Dopamine; Feeding Behavior; gamma-Aminobutyric Acid; Humans; Learning; Memory; Muscimol; Oxazoles; Receptors, Cell Surface; Receptors, GABA-A; Seizures | 1980 |
Ligand-binding and autoradiographic studies of GABA-receptors in tissue culture.
Topics: Animals; Autoradiography; Culture Techniques; gamma-Aminobutyric Acid; Kinetics; Ligands; Muscimol; Receptors, Cell Surface; Receptors, GABA-A; Subcellular Fractions | 1981 |
GABA agonists. Development and interactions with the GABA receptor complex.
Topics: Amino Acids; Animals; Benzodiazepines; Brain Chemistry; Cats; Chemical Phenomena; Chemistry; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Isonicotinic Acids; Mice; Models, Structural; Muscimol; Receptors, Cell Surface; Receptors, GABA-A; Structure-Activity Relationship | 1981 |
Cellular compartments of GABA in brain and their relationship to anticonvulsant activity.
Topics: 4-Aminobutyrate Transaminase; Aminocaproates; Aminooxyacetic Acid; Animals; Anticonvulsants; Brain; Corpus Striatum; Denervation; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Kainic Acid; Kinetics; Mesencephalon; Muscimol; Neuroglia; Neurons; Rats; Receptors, Cell Surface; Receptors, GABA-A; Seizures; Substantia Nigra; Tissue Distribution; Valproic Acid; Vigabatrin | 1981 |
Muscimol, a psychoactive constituent of Amanita muscaria, as a medicinal chemical model structure.
Topics: Agaricales; Amanita; Animals; gamma-Aminobutyric Acid; Isonicotinic Acids; Isoxazoles; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Structural; Molecular Conformation; Muscimol; Nipecotic Acids; Oxazoles; Receptors, Cell Surface; Receptors, GABA-A; Stereoisomerism | 1981 |
GABA and acute psychoses.
Topics: Acute Disease; Animals; Brain; Cats; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Limbic System; Muscimol; Porphyrias; Psychoses, Substance-Induced; Psychotic Disorders; Receptors, Cell Surface; Receptors, GABA-A; Schizophrenia | 1982 |
gamma-Aminobutyric acid and cardiovascular function.
Topics: Animals; Atropine; Baclofen; Blood Pressure; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; Hypertension; Muscimol; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Vagotomy | 1983 |
Molecular pharmacology of the GABA receptors and GABA agonists.
Topics: Animals; Bicuculline; gamma-Aminobutyric Acid; Humans; Isoxazoles; Molecular Conformation; Muscimol; Neurons; Receptors, Cell Surface; Receptors, GABA-A; Stereoisomerism; Synapses | 1983 |
Anterior pituitary GABA receptors in relation to prolactin secretion.
Topics: Animals; Diestrus; Estradiol; Female; gamma-Aminobutyric Acid; Lactation; Muscimol; Picrotoxin; Pituitary Gland, Anterior; Pregnancy; Prolactin; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Biochemical and electrophysiological characteristics of mammalian GABA receptors.
Topics: Animals; Brain; Cell Membrane; Central Nervous System; Electrophysiology; gamma-Aminobutyric Acid; Kinetics; Muscimol; Neurons; Receptors, Cell Surface; Receptors, GABA-A; Synapses | 1983 |
GABA and respiratory function.
Topics: Animals; Baclofen; GABA Antagonists; gamma-Aminobutyric Acid; Hydroxybutyrates; Injections, Intraventricular; Iontophoresis; Medulla Oblongata; Muscimol; Respiration | 1984 |
Involvement of GABA and other inhibitory amino acids in thermoregulation.
Topics: Allylglycine; Amino Acids; Animals; Body Temperature Regulation; Brain; Fever; gamma-Aminobutyric Acid; Hypothermia; Muscimol; Taurine | 1984 |
GABA system: clinical research and treatment of tardive dyskinesia.
Topics: Alkynes; Aminocaproates; Benzodiazepines; Clinical Trials as Topic; Corpus Striatum; Dopamine; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Humans; Isoxazoles; Muscimol; Substantia Nigra; Valproic Acid; Vigabatrin | 1983 |
GABAergic mechanisms in the control of PRL and GH release.
Topics: Animals; gamma-Aminobutyric Acid; Growth Hormone; Muscimol; Prolactin; Rats | 1981 |
The role of GABA in the basal ganglia and limbic system for behaviour.
Topics: Animals; Basal Ganglia; Behavior, Animal; Catalepsy; Corpus Striatum; gamma-Aminobutyric Acid; Globus Pallidus; Humans; Limbic System; Muscimol; Substantia Nigra | 1981 |
Role of GABA in the striatal output system: globus pallidus, nucleus entopeduncularis, substantia nigra and nucleus subthalamicus.
Topics: Animals; Basal Ganglia; Behavior, Animal; Corpus Striatum; Dopamine; Functional Laterality; gamma-Aminobutyric Acid; Globus Pallidus; Isoxazoles; Male; Muscimol; Rats; Rats, Inbred Strains; Substantia Nigra; Thalamus | 1981 |
The neuroanatomical specificity of ethanol action on ligand-gated ion channels: a hypothesis.
Topics: Animals; Brain; Ethanol; gamma-Aminobutyric Acid; Glycine; Humans; Ion Channels; Ligands; Models, Neurological; Muscimol; N-Methylaspartate; Nicotine; Receptors, GABA-A | 1993 |
Astrocytic GABA receptors.
Topics: Animals; Astrocytes; Baclofen; Barbiturates; Benzodiazepines; Carbolines; Cats; Chloride Channels; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Humans; Membrane Potentials; Muscimol; Nerve Tissue Proteins; Neurons; Neurotoxins; Pituitary Gland; Rats; Receptors, GABA; Second Messenger Systems; Synaptic Transmission | 1994 |
[Neurochemical and pharmacological studies on brain GABA receptors].
Topics: Animals; Bicuculline; Binding Sites; Brain; gamma-Aminobutyric Acid; Muscimol; Pyridazines; Rats; Receptors, GABA-A; Surface-Active Agents; Up-Regulation | 1994 |
The 'ABC' of GABA receptors: a brief review.
Topics: Animals; Central Nervous System; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Ion Channels; Mammals; Molecular Conformation; Muscimol; Organophosphorus Compounds; Receptors, GABA | 1999 |
GABA and muscimol as reversible inactivation tools in learning and memory.
Topics: Animals; Brain; GABA Agonists; gamma-Aminobutyric Acid; Learning; Memory; Muscimol | 2000 |
GABA potentiation: a logical pharmacological approach for the treatment of acute ischaemic stroke.
Topics: Acute Disease; Animals; Brain; Brain Ischemia; Chlormethiazole; GABA Agonists; gamma-Aminobutyric Acid; Humans; Muscimol; Neuroprotective Agents; Receptors, GABA-A | 2000 |
Gamma-aminobutyric acid (GABA) regulation of GnRH secretion in sheep.
Topics: Animals; Bicuculline; Female; GABA Antagonists; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Hypothalamus, Middle; Luteinizing Hormone; Muscimol; Preoptic Area; Rats; Receptors, GABA; Seasons; Secretory Rate; Sheep | 2002 |
[Modulation by the GABA of the ventro-oral-pontine reticular REM sleep-inducing neurons].
Topics: Animals; Cats; Cells, Cultured; Circadian Rhythm; GABA Agonists; gamma-Aminobutyric Acid; Humans; Muscimol; Neurons; Pons; Presynaptic Terminals; Rats; Reticular Formation; Sleep, REM; Time Factors; Wakefulness | 2007 |
Psychoactive Isoxazoles, Muscimol, and Isoxazole Derivatives from the Amanita (Agaricomycetes) Species: Review of New Trends in Synthesis, Dosage, and Biological Properties.
Topics: Amanita; GABA Agonists; gamma-Aminobutyric Acid; Isoxazoles; Muscimol | 2023 |
7 trial(s) available for muscimol and gamma-aminobutyric acid
| Article | Year |
|---|---|
Huntington's disease: treatment with muscimol, a GABA-mimetic drug.
Topics: Activities of Daily Living; Adolescent; Adult; Clinical Trials as Topic; Cognition; Double-Blind Method; Female; gamma-Aminobutyric Acid; Humans; Huntington Disease; Male; Middle Aged; Muscimol; Oxazoles; Placebos | 1978 |
GABA agonist-induced changes in motor, oculomotor, and attention measures correlate in schizophrenics with tardive dyskinesia.
Topics: Adult; Antipsychotic Agents; Attention; Chronic Disease; Double-Blind Method; Dyskinesia, Drug-Induced; Efferent Pathways; Female; gamma-Aminobutyric Acid; Humans; Limbic System; Male; Middle Aged; Muscimol; Neurologic Examination; Psychomotor Performance; Receptors, GABA-A; Saccades; Schizophrenia; Schizophrenic Psychology; Substantia Nigra; Thalamic Nuclei | 1992 |
gamma-Aminobutyric acid enhances the tone of human internal anal sphincter.
Topics: Anal Canal; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Humans; Muscimol; Muscle Contraction; Muscle Relaxation; Pressure; Receptors, GABA-A; Valproic Acid | 1991 |
GABA system: clinical research and treatment of tardive dyskinesia.
Topics: Alkynes; Aminocaproates; Benzodiazepines; Clinical Trials as Topic; Corpus Striatum; Dopamine; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Humans; Isoxazoles; Muscimol; Substantia Nigra; Valproic Acid; Vigabatrin | 1983 |
GABA and movement disorders.
Topics: Anticonvulsants; Baclofen; Clinical Trials as Topic; Double-Blind Method; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Humans; Huntington Disease; Isoniazid; Movement Disorders; Muscimol; Parkinson Disease; Valproic Acid | 1981 |
Effects of gamma aminobutyric acid (GABA) and muscimol on endocrine pancreatic function in man.
Topics: Adolescent; Adult; Blood Glucose; C-Peptide; Female; gamma-Aminobutyric Acid; Glucagon; Humans; Insulin; Islets of Langerhans; Male; Middle Aged; Muscimol; Oxazoles | 1982 |
GABAAergic inhibition or dopamine denervation of the A11 hypothalamic nucleus induces trigeminal analgesia.
Topics: Animals; Calcitonin Gene-Related Peptide; Denervation; Dopamine; Dorsomedial Hypothalamic Nucleus; Functional Laterality; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Male; Motor Activity; Muscimol; Neural Pathways; Neurons; Oxidopamine; Pain Measurement; Rats; Sympatholytics; Trigeminal Neuralgia | 2015 |
1508 other study(ies) available for muscimol and gamma-aminobutyric acid
| Article | Year |
|---|---|
Kojic amine--a novel gamma-aminobutyric acid analogue.
Topics: Animals; Anticonvulsants; Cats; Female; gamma-Aminobutyric Acid; Male; Mice; Muscle Relaxants, Central; Pyrones; Rats; Spinal Cord; Structure-Activity Relationship | 1979 |
Condensation of muscimol or thiomuscimol with aminopyridazines yields GABA-A antagonists.
Topics: Animals; Binding, Competitive; Convulsants; Female; GABA-A Receptor Antagonists; In Vitro Techniques; Mice; Models, Molecular; Molecular Conformation; Muscimol; Pyridazines; Radioligand Assay; Rats; Receptors, GABA-A; Structure-Activity Relationship | 1992 |
Orally active and potent inhibitors of gamma-aminobutyric acid uptake.
Topics: 4-Aminobutyrate Transaminase; Administration, Oral; Alkylation; Amino Acids; Animals; Brain; Carboxylic Acids; gamma-Aminobutyric Acid; Glutamate Decarboxylase; In Vitro Techniques; Male; Neurotransmitter Uptake Inhibitors; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Neurotransmitter; Stereoisomerism; Synaptosomes | 1985 |
GABA agonists. Resolution, absolute stereochemistry, and enantioselectivity of (S)-(+)- and (R)-(-)-dihydromuscimol.
Topics: Animals; Bicuculline; Brain; Cats; Chemical Phenomena; Chemistry; Diazepam; gamma-Aminobutyric Acid; Isoxazoles; Molecular Conformation; Muscimol; Neurons; Oxazolidinones; Piperidines; Rats; Receptors, GABA-A; Spinal Cord; Stereoisomerism; Structure-Activity Relationship; Synaptic Membranes | 1985 |
Synthesis and pharmacological evaluation of gamma-aminobutyric acid analogues. New ligand for GABAB sites.
Topics: Animals; Baclofen; Cerebral Cortex; gamma-Aminobutyric Acid; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, GABA-B; Stereoisomerism; Structure-Activity Relationship | 1987 |
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Epimeric cis-decahydroquinoline-5-carboxylic acids: effects on gamma-aminobutyric acid uptake and receptor binding in vitro.
Topics: Animals; Brain; Chemical Phenomena; Chemistry; gamma-Aminobutyric Acid; In Vitro Techniques; Molecular Conformation; Quinolines; Rats; Receptors, Cell Surface; Receptors, GABA-A; Stereoisomerism; Synaptosomes | 1981 |
New anticonvulsants: Schiff bases of gamma-aminobutyric acid and gamma-aminobutyramide.
Topics: Animals; Anticonvulsants; Bicuculline; Brain; Cerebellum; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Ganglia, Spinal; Humans; In Vitro Techniques; Lethal Dose 50; Male; Mice; Rats; Schiff Bases | 1980 |
(+/-)-trans-2-(Aminomethyl)cyclobutanecarboxylic acid hydrochloride: a rigid analogue of gamma-aminobutyric acid.
Topics: Animals; Binding Sites; Binding, Competitive; Cyclobutanes; gamma-Aminobutyric Acid; In Vitro Techniques; Rats; Synaptic Membranes | 1980 |
5-Substituted imidazole-4-acetic acid analogues: synthesis, modeling, and pharmacological characterization of a series of novel gamma-aminobutyric acid(C) receptor agonists.
Topics: Animals; Brain; Cell Line; GABA Agonists; GABA-A Receptor Agonists; Humans; Imidazoles; In Vitro Techniques; Ligands; Membrane Potentials; Models, Molecular; Mutation; Oocytes; Patch-Clamp Techniques; Protein Structure, Tertiary; Protein Subunits; Radioligand Assay; Rats; Receptors, GABA; Receptors, GABA-A; Stereoisomerism; Structure-Activity Relationship | 2007 |
Novel gamma-aminobutyric acid rho1 receptor antagonists; synthesis, pharmacological activity and structure-activity relationships.
Topics: Animals; Female; GABA Antagonists; Ligands; Models, Molecular; Molecular Structure; Oocytes; Structure-Activity Relationship; Xenopus laevis | 2008 |
Synthesis and biological evaluation of 4-(aminomethyl)-1-hydroxypyrazole analogues of muscimol as γ-aminobutyric acid(a) receptor agonists.
Topics: Computer Simulation; GABA-A Receptor Agonists; Magnetic Resonance Spectroscopy; Models, Molecular; Muscimol; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship | 2013 |
Design, Synthesis, and Pharmacological Evaluation of Fluorescent and Biotinylated Antagonists of ρ1 GABAC Receptors.
Topics: | 2013 |
Synthesis and pharmacological evaluation of 6-aminonicotinic acid analogues as novel GABA(A) receptor agonists.
Topics: Dose-Response Relationship, Drug; GABA-A Receptor Agonists; Humans; Ligands; Models, Molecular; Molecular Structure; Niacin; Receptors, GABA-A; Structure-Activity Relationship | 2014 |
Behavioural evidence for GABAergic activity of the benzodiazepine flurazepam.
Topics: Animals; Anti-Anxiety Agents; Baclofen; Behavior, Animal; Flurazepam; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rotation; Substantia Nigra; Synaptic Transmission; Time Factors | 1978 |
Benzodiazepines potentiate GABA-dopamine stereotyped dependent gnawing in mice.
Topics: Animals; Anti-Anxiety Agents; Behavior; Benzodiazepines; Dopamine; Drug Synergism; gamma-Aminobutyric Acid; Humans; Methylphenidate; Mice; Muscimol; Stereotyped Behavior | 1979 |
Cataleptic and anticataleptic effects of muscimol and gabaculine injected into globus pallidus and substantia nigra, and interactions with haloperidol or benzodiazepines.
Topics: 4-Aminobutyrate Transaminase; Animals; Anti-Anxiety Agents; Benzodiazepines; Catalepsy; Corpus Striatum; Cyclohexanecarboxylic Acids; Cyclohexylamines; Drug Interactions; gamma-Aminobutyric Acid; Globus Pallidus; Haloperidol; Homovanillic Acid; Humans; Injections; Male; Muscimol; Oxazoles; Rats; Substantia Nigra; Transaminases | 1978 |
Improvement in tardive dyskinesia after muscimol therapy.
Topics: Adult; Aged; Antipsychotic Agents; Dopamine; Drug Evaluation; Dyskinesia, Drug-Induced; Extrapyramidal Tracts; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Muscimol; Oxazoles; Receptors, Dopamine; Schizophrenia; Stimulation, Chemical; Synaptic Transmission | 1979 |
Muscimol and related GABA receptor agonists: the potency of GABAergic drugs in vivo determined after intranigral injection.
Topics: Animals; gamma-Aminobutyric Acid; Humans; Injections; Male; Muscimol; Oxazoles; Rats; Receptors, Drug; Stereotyped Behavior; Substantia Nigra; Time Factors | 1979 |
GABAergic and glycinergic mechanisms within the substantia nigra: pharmacological specificity of dopamine-independent contralateral turning behavior and interactions with other neurotransmitters.
Topics: Animals; Behavior; Dopamine; gamma-Aminobutyric Acid; Glycine; Humans; Hydroxydopamines; Kainic Acid; Male; Muscimol; Neurotransmitter Agents; Rats; Stereotyped Behavior; Substantia Nigra; Time Factors | 1979 |
GABA agonists and antagonists.
Topics: Animals; Bicuculline; Brain; Cell Membrane; GABA Antagonists; gamma-Aminobutyric Acid; Models, Molecular; Molecular Conformation; Muscimol; Neurotransmitter Agents; Receptors, Drug; Structure-Activity Relationship | 1979 |
Ontogeny of GABA and benzodiazepine receptors: effects of Triton X-100, bromide and muscimol.
Topics: Age Factors; Animals; Anti-Anxiety Agents; Bromides; Cerebellum; Female; Flunitrazepam; gamma-Aminobutyric Acid; Muscimol; Oxazoles; Polyethylene Glycols; Pregnancy; Rats; Receptors, Drug | 1979 |
Effects of benzodiazepines and barbiturates in a GABA-dependent animal model: interactions with muscimol in the globus pallidus [proceedings].
Topics: Animals; Anti-Anxiety Agents; Barbiturates; Behavior, Animal; Benzodiazepines; Drug Interactions; Female; gamma-Aminobutyric Acid; Globus Pallidus; Muscimol; Oxazoles; Rats | 1979 |
Gamma-aminobutyric-acid analogues.
Topics: Animals; Anticonvulsants; Benzodiazepines; gamma-Aminobutyric Acid; Muscimol; Rats | 1978 |
An investigation of whether septal gamma-aminobutyrate-containing interneurons are involved in the reduction in the turnover rate of acetylcholine elicited by substance P and beta-endorphin in the hippocampus.
Topics: Acetylcholine; Animals; Brain Mapping; Endorphins; gamma-Aminobutyric Acid; Hippocampus; Interneurons; Male; Muscimol; Neural Pathways; Rats; Septum Pellucidum; Substance P | 1979 |
Effects of systemically applied GABA agonists and antagonists on wave-spike ECoG activity in rat.
Topics: Action Potentials; Animals; Behavior, Animal; Bicuculline; Electroencephalography; Epilepsy, Absence; GABA Antagonists; gamma-Aminobutyric Acid; Imidazoles; Male; Muscimol; Photic Stimulation; Picrotoxin; Rats; Strychnine | 1979 |
Modification of the behavioural effects of amphetamine by a GABA agonist in a primate species.
Topics: Animals; Behavior, Animal; Callitrichinae; Dextroamphetamine; Dopamine; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Haplorhini; Humans; Male; Motor Activity; Muscimol; Oxazoles; Stereotyped Behavior | 1979 |
The neuropharmacology of a novel gamma-aminobutyric acid analog, kojic amine.
Topics: 4-Aminobutyrate Transaminase; Animals; Bicuculline; Bufo marinus; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Nervous System; Pyrans; Pyrones; Rats; Spinal Cord | 1979 |
L-histidine: effects on sensitivity of cat spinal neurones to amino acids.
Topics: Amino Acids; Amino Acids, Diamino; Animals; Aspartic Acid; beta-Alanine; Cats; Drug Interactions; gamma-Aminobutyric Acid; Glutamates; Histidine; Kainic Acid; Muscimol; Spinal Cord | 1979 |
Stimulation of prolactin and growth hormone secretion by muscimol, a gamma-aminobutyric acid agonist.
Topics: Adult; Aged; Chronic Disease; Female; gamma-Aminobutyric Acid; Growth Hormone; Humans; Huntington Disease; Kinetics; Male; Middle Aged; Muscimol; Oxazoles; Prolactin; Schizophrenia | 1978 |
The effect of muscimol on prolactin secretion in male rats.
Topics: Animals; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Haloperidol; Male; Methyltyrosines; Muscimol; Oxazoles; Premedication; Prolactin; Rats; Receptors, Neurotransmitter | 1978 |
Gamma-aminobutyric acid binding in mammalian brain: receptor-like specificity of sodium-independent sites.
Topics: Animals; Bicuculline; Brain; gamma-Aminobutyric Acid; Muscimol; Rats; Receptors, Drug; Receptors, Neurotransmitter; Sodium | 1978 |
Isoguvacine, isonipecotic acid, muscimol and N-methyl isoguvacine on the GABA receptor in rat sympathetic ganglia.
Topics: Animals; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Ganglia, Autonomic; Isonicotinic Acids; Isonipecotic Acids; Membrane Potentials; Muscimol; Rats; Receptors, Neurotransmitter; Structure-Activity Relationship | 1978 |
Denervation supersensitivity in the striatonigral GABA pathway.
Topics: Animals; Behavior; Behavior, Animal; Corpus Striatum; Denervation; Functional Laterality; gamma-Aminobutyric Acid; Kainic Acid; Male; Muscimol; Neural Pathways; Pyrrolidines; Rats; Receptors, Neurotransmitter; Substantia Nigra | 1978 |
Opiate receptor agonists as modulators of gamma-aminobutyric acid turnover in the nucleus caudatus, globus pallidus and substantia nigra of the rat.
Topics: Animals; Catalepsy; Caudate Nucleus; Endorphins; gamma-Aminobutyric Acid; Globus Pallidus; Humans; Male; Morphine; Muscimol; Naltrexone; Rats; Receptors, Opioid; Substantia Nigra | 1978 |
gamma-Aminobutyric acid receptors visualized in spinal cord cultures by [3H]muscimol autoradiography.
Topics: Animals; Autoradiography; Cells, Cultured; gamma-Aminobutyric Acid; Mice; Muscimol; Receptors, Neurotransmitter; Spinal Cord | 1978 |
Facilitation by GABA of the potassium-evoked release of 3-H-noradrenaline from the rat occipital cortex.
Topics: Animals; Bicuculline; Cerebral Cortex; gamma-Aminobutyric Acid; Male; Muscimol; Nictitating Membrane; Norepinephrine; Picrotoxin; Potassium; Rats; Stimulation, Chemical; Synaptic Transmission; Tyramine | 1979 |
Solubilization of gamma-aminobutyric acid receptor protein from mammalian brain.
Topics: Animals; Brain Chemistry; Cattle; Deoxycholic Acid; gamma-Aminobutyric Acid; Muscimol; Protein Binding; Receptors, Neurotransmitter; Solubility | 1979 |
Behavioral and biochemical analysis of GABA-mediated inhibition in the early chick embryo.
Topics: 4-Aminobutyrate Transaminase; Age Factors; Aminobutyrates; Animals; Carboxy-Lyases; Chick Embryo; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Motor Activity; Muscimol; Neural Inhibition; Picrotoxin; Receptors, Neurotransmitter; Spinal Cord; Succinates; Transaminases | 1979 |
Presynaptic GABA autoreceptors on GABAergic nerve endings of the rat substantia nigra.
Topics: Animals; Calcium; Cerebral Cortex; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Nerve Endings; Picrotoxin; Potassium; Rats; Receptors, Cell Surface; Substantia Nigra | 1979 |
The localization of receptor binding sites in the substantia nigra and striatum of the rat.
Topics: Animals; Brain Mapping; Corpus Striatum; Dihydroalprenolol; Fluphenazine; gamma-Aminobutyric Acid; Hydroxydopamines; Kainic Acid; Male; Muscimol; Naloxone; Neural Pathways; Neurons; Quinuclidinyl Benzilate; Rats; Receptors, Adrenergic, beta; Receptors, Cholinergic; Receptors, Dopamine; Receptors, Neurotransmitter; Receptors, Opioid; Substantia Nigra | 1979 |
GABA agonists and potential antagonists related to muscimol.
Topics: Animals; Dose-Response Relationship, Drug; Functional Laterality; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Isoxazoles; Male; Muscimol; Oxazoles; Rats; Receptors, Neurotransmitter; Stereotyped Behavior; Substantia Nigra | 1979 |
GABA-receptors in the substantia nigra controlling cyclic-GMP in the cerebellar cortex.
Topics: Animals; Cerebellar Cortex; Corpus Striatum; Cyclic GMP; gamma-Aminobutyric Acid; Haloperidol; Kainic Acid; Muscimol; Rats; Receptors, Drug; Substantia Nigra | 1979 |
Effects of diazepam and muscimol on GABA-mediated neurotransmission: interactions with inosine and nicotinamide.
Topics: Animals; Corpus Striatum; Diazepam; Drug Interactions; Female; gamma-Aminobutyric Acid; Globus Pallidus; Inosine; Muscimol; Niacinamide; Oxazoles; Rats; Synaptic Transmission; Time Factors | 1979 |
Pharmacology of (+)- and (-)-baclofen: GABA-dependant rotational behaviour and [3H]GABA receptor binding studies.
Topics: Animals; Baclofen; gamma-Aminobutyric Acid; Male; Motor Activity; Muscimol; Rats; Receptors, Neurotransmitter; Stereoisomerism; Substantia Nigra | 1979 |
High-affinity binding of [3H]muscimol to subcellular particles of a neurone-enriched culture of embryonic rat brain.
Topics: Animals; Brain; Brain Chemistry; Culture Techniques; gamma-Aminobutyric Acid; Muscimol; Oxazoles; Rats; Receptors, Neurotransmitter; Subcellular Fractions | 1979 |
The depolarizing responses to GABA in rat sensory ganglia in vivo and in vitro. A study of the role of glial uptake.
Topics: Animals; Electric Conductivity; gamma-Aminobutyric Acid; Ganglia, Spinal; In Vitro Techniques; Membrane Potentials; Muscimol; Neuroglia; Rats; Receptors, Neurotransmitter; Taurine | 1979 |
Anticonvulsant activity of muscimol against seizures induced by impairment of GABA-mediated neurotransmission.
Topics: Animals; Anticonvulsants; Bicuculline; gamma-Aminobutyric Acid; Isoniazid; Male; Muscimol; Oxazoles; Pentylenetetrazole; Picrotoxin; Rats; Seizures; Strychnine; Synaptic Transmission | 1979 |
Stimulation of benzodiazepine receptor binding by gamma-aminobutyric acid.
Topics: Animals; Bicuculline; Brain; Cerebral Cortex; Diazepam; gamma-Aminobutyric Acid; Kinetics; Membranes; Muscimol; Rats; Receptors, Drug | 1979 |
Dopaminergic, GABA-ergic and cholinergic interaction in the regulation of striatal acetylcholine concentration.
Topics: Acetylcholine; Aminooxyacetic Acid; Animals; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Male; Muscimol; Parasympathetic Nervous System; Rats; Time Factors; Valproic Acid | 1978 |
Involvement of central GABA-ergic systems in convulsions and aggressive behavior.
Topics: 4-Aminobutyrate Transaminase; Aggression; Allylglycine; Animals; Bicuculline; Brain; Fatty Acids; gamma-Aminobutyric Acid; Humans; Kinetics; Mice; Muscimol; Picrotoxin; Rats; Seizures; Structure-Activity Relationship; Valproic Acid | 1979 |
Effects of GABA-mimetic agents on the cat spinal cord.
Topics: Animals; Bicuculline; Cats; Drug Interactions; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Spinal; Ibotenic Acid; Isonicotinic Acids; Isoxazoles; Male; Muscimol; Neurons, Afferent; Spinal Cord | 1979 |
Characterization of the binding of [3H]muscimol, a potent gamma-aminobutyric acid agonist, to rat brain synaptosomal membranes using a filtration assay.
Topics: Animals; Binding, Competitive; Brain; Cerebellum; gamma-Aminobutyric Acid; Kinetics; Muscimol; Oxazoles; Rats; Receptors, Drug; Synaptic Membranes; Tissue Distribution | 1979 |
gamma-Aminobutyric acid receptor binding and uptake in membrane fractions of crayfish muscle.
Topics: Acetylcholinesterase; Animals; Astacoidea; Binding, Competitive; Cell Fractionation; Cell Membrane; gamma-Aminobutyric Acid; Intracellular Membranes; Kinetics; Muscimol; Muscles; Receptors, Drug | 1979 |
Effects of the GABA receptor agonist muscimol on the turnover of brain dopamine and on the motor activity of rats.
Topics: Animals; Brain; Cell Nucleus; Dihydroxyphenylalanine; Dopamine; gamma-Aminobutyric Acid; Male; Motor Activity; Muscimol; Norepinephrine; Oxazoles; Rats | 1979 |
gamma-Aminobutyric acid receptors in cerebellar membranes of rat brain after a treatment with Triton X-100.
Topics: Animals; Binding Sites; Cerebellum; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Kinetics; Male; Membranes; Muscimol; Polyethylene Glycols; Rats; Sodium; Subcellular Fractions | 1979 |
Characterization of [3H]muscimol binding to mouse brain membranes.
Topics: Animals; Binding, Competitive; Brain; Detergents; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Membranes; Mice; Muscimol; Osmolar Concentration; Oxazoles; Receptors, Drug | 1979 |
Dihydromuscimol, thiomuscimol and related heterocyclic compounds as GABA analogues.
Topics: Animals; Brain; Cats; Cell Membrane; gamma-Aminobutyric Acid; Muscimol; Neurons; Oxazoles; Oxazolidinones; Rats; Receptors, Drug; Spinal Cord; Structure-Activity Relationship | 1979 |
Enhancement of the binding of 3H-diazepam to rat brain membranes in vitro by SQ 20009, A novel anxiolytic, gamma-aminobutyric acid (GABA) and muscimol.
Topics: Animals; Bicuculline; Brain; Diazepam; Etazolate; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Membranes; Muscimol; Nicotinic Acids; Oxazoles; Picrotoxin; Rats; Stimulation, Chemical | 1979 |
Characteristics of muscimol accumulation in mouse brain after systemic administration.
Topics: Animals; Bicuculline; Brain; gamma-Aminobutyric Acid; History, 18th Century; Injections, Intravenous; Mice; Muscimol; Oxazoles; Phenobarbital; Time Factors | 1979 |
GABA receptor control of parasympathetic outflow to heart: characterization and brainstem localization.
Topics: Animals; Bicuculline; Blood Pressure; Brain Stem; Cats; gamma-Aminobutyric Acid; Heart; Heart Rate; Isoniazid; Muscimol; Receptors, Drug; Vagus Nerve | 1979 |
Evidence for two types of binding of 3H-gaba and 3H-muscimol in rat cerebral cortex and cerebellum.
Topics: Animals; Brain Stem; Cerebellum; Cerebral Cortex; Corpus Striatum; gamma-Aminobutyric Acid; Male; Muscimol; Organ Specificity; Oxazoles; Radioligand Assay; Rats; Receptors, Drug; Substrate Specificity; Synaptosomes | 1979 |
Partial agonists for brain GABA/benzodiazepine receptor complex.
Topics: Animals; Benzodiazepines; Bicuculline; Brain; Crotonates; Diazepam; GABA Antagonists; gamma-Aminobutyric Acid; Imidazoles; Isoxazoles; Muscimol; Piperidines; Rats; Receptors, Drug; Sulfonic Acids | 1979 |
The GABA agonist THIP a muscimol analogue, does not interfere with the benzodiazepine binding site on rats cortical membranes.
Topics: Animals; Cerebral Cortex; Diazepam; gamma-Aminobutyric Acid; Imidazoles; In Vitro Techniques; Isonicotinic Acids; Male; Muscimol; Oxazoles; Rats; Receptors, Drug; Taurine | 1979 |
Turning behaviour induced by injection of muscimol or picrotoxin into the substantia nigra demonstrates dual GABA components.
Topics: Animals; gamma-Aminobutyric Acid; Male; Movement; Muscimol; Organ Specificity; Oxazoles; Picrotoxin; Rats; Substantia Nigra | 1979 |
[Role of the GABA-ergic systems of the brain in manifesting the activating effect of diazepam].
Topics: Animals; Bicuculline; Brain; Diazepam; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Motor Activity; Muscimol; Rats; Receptors, Drug; Self Stimulation | 1979 |
gamma-Aminobutyric acid receptor function in rat anterior pituitary: evidence for control of prolactin release.
Topics: Animals; Apomorphine; Bicuculline; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Haloperidol; Male; Morphine; Muscimol; Pituitary Gland, Anterior; Prolactin; Rats; Receptors, Drug | 1979 |
Dual gamma-aminobutyric acid control of prolactin secretion in the rat.
Topics: Animals; Bicuculline; Female; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Methyltyrosines; Muscimol; Oxazoles; Picrotoxin; Pituitary Gland, Anterior; Prolactin; Rats | 1979 |
Increase in striatal acetylcholine levels by GABA mimetic drugs: lack of involvement of the nigro-striatal dopaminergic neurons.
Topics: Acetylcholine; Animals; Corpus Striatum; gamma-Aminobutyric Acid; Hydroxydopamines; Male; Muscimol; Oxazoles; Rats | 1979 |
Baclofen and muscimol: behavioural and neurochemical sequelae of unilateral intranigral administration and effects on 3H-GABA receptor binding.
Topics: Aminobutyrates; Animals; Baclofen; Behavior, Animal; Brain Chemistry; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Hydroxydopamines; Injections; Male; Muscimol; Oxazoles; Rats; Receptors, Drug; Substantia Nigra; Time Factors | 1979 |
Action of gamma-aminobutyric acid on hypothalamo-neurohypophysial axons.
Topics: Animals; Axons; Bicuculline; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials; Female; gamma-Aminobutyric Acid; Hypothalamo-Hypophyseal System; Male; Muscimol; Pituitary Gland, Posterior; Rats | 1979 |
Solubilization and partial purification of the GABA receptor from mouse brain and a binding assay for the solubilized receptor.
Topics: Animals; Binding, Competitive; Brain; Bungarotoxins; gamma-Aminobutyric Acid; Kinetics; Lysophosphatidylcholines; Mice; Muscimol; Receptors, Drug; Solubility | 1979 |
GABAergic mediation in the inhibition of hippocampal acetylcholine turnover rate elicited by delta 9-tetrahydrocannabinol.
Topics: Acetylcholine; Animals; Bicuculline; Dopamine; Dronabinol; gamma-Aminobutyric Acid; Hippocampus; Kinetics; Male; Muscimol; Naltrexone; Norepinephrine; Rats; Substantia Nigra | 1979 |
Symmetric bilateral changes in dopamine release from the caudate nuclei of the cat induced by unilateral nigral application of glycine and GABA-related compounds.
Topics: Animals; Cats; Caudate Nucleus; Diazepam; Dominance, Cerebral; Dopamine; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Muscimol; Neural Pathways; Picrotoxin; Potassium; Strychnine; Substantia Nigra; Tyrosine | 1979 |
Central antihypertensive properties of muscimol and related gamma-aminobutyric acid agonists and the interaction of muscimol with baroreceptor reflexes.
Topics: Animals; Blood Pressure; Cats; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Heart Rate; Male; Muscimol; Oxazoles; Pressoreceptors; Reflex; Vasomotor System | 1979 |
Solubilization of histamine H-1, GABA and benzodiazepine receptors.
Topics: Animals; Binding, Competitive; Brain; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Male; Muscimol; Pyrilamine; Rats; Receptors, Drug; Receptors, Histamine; Receptors, Histamine H1 | 1979 |
Influence of inhibitors of the high affinity GABA uptake on seizure thresholds in mice.
Topics: Animals; Atropine; Brain Chemistry; Electroshock; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Nipecotic Acids; Parasympathetic Nervous System; Pentylenetetrazole; Seizures | 1979 |
Reduction of gamma-aminobutyric acid (GABA)-mediated transmission by a convulsant benzodiazepine.
Topics: Animals; Benzodiazepinones; Bicuculline; Cats; Convulsants; Female; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Pentylenetetrazole; Picrotoxin; Reflex; Spinal Cord; Strychnine | 1979 |
THIP and isoguvacine are partial agonists of GABA-stimulated benzodiazepine receptor binding.
Topics: Animals; Benzodiazepines; Cerebral Cortex; Drug Synergism; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Isonicotinic Acids; Isoxazoles; Muscimol; Oxazoles; Rats; Receptors, Drug | 1979 |
Evidence that GABA in the nucleus dorsalis raphé induces stimulation of locomotor activity and eating behavior.
Topics: Animals; Baclofen; Brain Chemistry; Brain Stem; Feeding Behavior; gamma-Aminobutyric Acid; Hydroxyindoleacetic Acid; Male; Motor Activity; Muscimol; Raphe Nuclei; Rats; Serotonin; Time Factors | 1979 |
The GABA-receptor: stereospecificity and structure-activity studies.
Topics: Animals; Binding, Competitive; Cell Membrane; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia; Humans; Kinetics; Muscimol; Rats; Receptors, Drug; Structure-Activity Relationship | 1979 |
[3H]Muscimol binding to rat cerebellar membranes.
Topics: Animals; Cell Membrane; Cerebellum; Female; gamma-Aminobutyric Acid; Kinetics; Male; Muscimol; Oxazoles; Rats; Receptors, Drug; Tritium | 1979 |
More muscimol binding sites than GABA binding sites in a particulate fraction of rat brain.
Topics: Animals; Binding Sites; Brain; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Male; Muscimol; Oxazoles; Rats | 1979 |
Comparison of the "specific" binding of [3H]GABA and [3H]muscimol to a particulate fraction of rat brain.
Topics: Animals; Brain; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Male; Muscimol; Nerve Tissue Proteins; Oxazoles; Protein Binding; Rats; Subcellular Fractions | 1979 |
Conformational analysis of muscimol, a GABA agonist.
Topics: Bicuculline; Binding Sites; gamma-Aminobutyric Acid; Isoxazoles; Models, Molecular; Molecular Conformation; Muscimol; Oxazoles; Quantum Theory | 1979 |
Paradoxical GABA excitation of nigral dopaminergic cells: indirect mediation through reticulata inhibitory neurons.
Topics: Animals; Dopamine; gamma-Aminobutyric Acid; Glutamates; Iontophoresis; Male; Muscimol; Neural Inhibition; Neurons; Rats; Stimulation, Chemical; Substantia Nigra | 1979 |
GABA and hypothalamic feeding systems. I. Topographic analysis of the effects of microinjections of muscimol.
Topics: Animals; Bicuculline; Brain Mapping; Digestive System; Eating; Female; gamma-Aminobutyric Acid; Gastric Juice; Hypothalamus; Hypothalamus, Middle; Injections, Intraventricular; Male; Muscimol; Oxazoles; Rats | 1979 |
Muscimol uptake, release and binding in rat brain slices.
Topics: Alanine; Animals; Binding, Competitive; Biological Transport; Cerebral Cortex; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Muscimol; Oxazoles; Rats; Receptors, Drug | 1978 |
Does uptake limit the actions of GABA agonists in vivo? Experiments with muscimol, isoguvacine and THIP in cat spinal cord.
Topics: Aminobutyrates; Animals; Biological Transport; Cats; gamma-Aminobutyric Acid; Isonicotinic Acids; Isoxazoles; Muscimol; Neurons; Nipecotic Acids; Oxazoles; Spinal Cord | 1978 |
Recent advances in the morphological localization of gamma-aminobutyric acid receptors in the cerebellum by means of [3H]muscimol.
Topics: Animals; Brain; Cerebellar Nuclei; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Oxazoles; Purkinje Cells; Rats | 1979 |
Contralateral turning evoked by the intranigral microinjection of muscimol and other GABA agonists.
Topics: Animals; Behavior; Caudate Nucleus; Dopamine Antagonists; Dose-Response Relationship, Drug; Ethanolamines; Female; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Imidazoles; Muscimol; Oxazoles; Picrotoxin; Putamen; Rats; Stereotyped Behavior; Substantia Nigra | 1978 |
GABA-dopamine interaction in substantia nigra and nucleus accumbens--relevance to behavioral stimulation and stereotyped behavior.
Topics: Animals; Behavior, Animal; Dopamine; gamma-Aminobutyric Acid; Humans; Motor Activity; Muscimol; Nucleus Accumbens; Rats; Septal Nuclei; Stereotyped Behavior; Substantia Nigra | 1978 |
A comparative study of the effects of muscimol and diazepam on the recall of noxious events.
Topics: Animals; Avoidance Learning; Diazepam; Dissociative Disorders; gamma-Aminobutyric Acid; Humans; Male; Memory; Mental Recall; Muscimol; Oxazoles; Rats | 1979 |
Modulatory effects of baclofen muscimol and GABA on interspecific aggressive behaviour in the rat.
Topics: Aggression; Aminobutyrates; Animals; Baclofen; gamma-Aminobutyric Acid; Humans; Male; Muscimol; Olfactory Bulb; Oxazoles; Rats | 1978 |
Amphetamine-induced circling behavior in rats: effects of unilateral microinjections of GABA and GABA-related drugs into substantia nigra.
Topics: Animals; Behavior; Bicuculline; Chlordiazepoxide; Dextroamphetamine; Dominance, Cerebral; gamma-Aminobutyric Acid; Humans; Male; Muscimol; Rats; Stereotyped Behavior; Substantia Nigra | 1979 |
Neuropharmacological spectrum of muscimol.
Topics: Animals; Anticonvulsants; Catalepsy; Drug Interactions; gamma-Aminobutyric Acid; Humans; Male; Mice; Motor Activity; Muscimol; Muscle Relaxants, Central; Nervous System; Oxazoles; Receptors, Drug | 1979 |
GABA in the ventral tegmental area: differential regional effects on locomotion, aggression and food intake after microinjection of GABA agonists and antagonists.
Topics: Aggression; Animals; Apomorphine; Behavior, Animal; Bicuculline; Carbachol; Cerebral Cortex; Dopamine; Feeding Behavior; gamma-Aminobutyric Acid; Haloperidol; Humans; Isoxazoles; Male; Methyltyrosines; Morphine; Motor Activity; Muscimol; Picrotoxin; Rats; Reserpine | 1979 |
Role of thalamic gamma-aminobutyrate in motor functions: catalepsy and ipsiversive turning after intrathalamic muscimol.
Topics: Animals; Brain Mapping; Catalepsy; Corpus Striatum; gamma-Aminobutyric Acid; Humans; Male; Motor Activity; Movement Disorders; Muscimol; Neural Pathways; Posture; Rats; Thalamus | 1979 |
Influence of baclofen and GABA-minetic agents on spontaneous and olfactory-bulb-ablation-induced muricidal behaviour in the rat.
Topics: Aggression; Aminobutyrates; Animals; Baclofen; gamma-Aminobutyric Acid; Humans; Male; Motor Activity; Muscimol; Olfactory Bulb; Rats | 1978 |
Response of dopamine neurons in substantia nigra to muscimol.
Topics: Animals; Bicuculline; Dopamine; Dose-Response Relationship, Drug; Evoked Potentials; gamma-Aminobutyric Acid; Male; Muscimol; Neurons; Oxazoles; Picrotoxin; Rats; Substantia Nigra | 1978 |
Effects of central GABA receptor agonism and antagonism on evoked diencephalic cardiovascular responses.
Topics: Animals; Bicuculline; Cats; Diazepam; Diencephalon; Electric Stimulation; gamma-Aminobutyric Acid; Hemodynamics; Muscimol; Receptors, Drug; Sympathetic Nervous System | 1978 |
Influence of GABA receptor agonists and antagonists on the binding of 3H-diazepam to the benzodiazepine receptor.
Topics: Animals; Benzodiazepines; Bicuculline; Brain; Diazepam; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Rats; Receptors, Drug | 1978 |
Homotaurine and muscimol mimic taurine and GABA effects on muscle tone and temperature regulation.
Topics: Amino Acids; Animals; Body Temperature Regulation; Electroencephalography; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Injections, Intraventricular; Male; Muscimol; Muscle Tonus; Oxazoles; Rabbits; Taurine | 1978 |
Interleukin-2 inhibits the GABA-induced Cl- current in identified Aplysia neurons.
Topics: Animals; Aplysia; Bicuculline; Chlorides; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia; In Vitro Techniques; Interleukin-2; Ion Channels; Membranes; Muscimol; Neurons; Picrotoxin; Recombinant Proteins; Seawater | 1992 |
Evidence for a modulation of human chorionic gonadotropin (hCG) subunit messenger ribonucleic acid levels and hCG secretion by gamma-aminobutyric acid in human first trimester placenta in vitro.
Topics: Bicuculline; Chorionic Gonadotropin; Culture Techniques; Female; gamma-Aminobutyric Acid; Humans; Muscimol; Placenta; Pregnancy; Pregnancy Trimester, First; Receptors, GABA-A; RNA, Messenger | 1992 |
Alterations in the gamma-aminobutyric acid-gated chloride channel following transient forebrain ischemia in the gerbil.
Topics: Animals; Autoradiography; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Chlorides; gamma-Aminobutyric Acid; Gerbillinae; Ion Channel Gating; Ischemic Attack, Transient; Male; Membrane Proteins; Motor Activity; Muscimol | 1992 |
Inhibitory role of gamma-amino-butyric acid in the rabbit urinary bladder.
Topics: Animals; Baclofen; Bicuculline; Carbachol; Depression, Chemical; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Rabbits; Receptors, GABA-A; Urinary Bladder | 1992 |
Effects of GABA receptor stimulation on the release of [3H]GABA from slices of rat neostriatum.
Topics: Animals; Convulsants; Corpus Striatum; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Isonicotinic Acids; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sodium Channels; Tetrodotoxin | 1992 |
Modulation of extracellular gamma-aminobutyric acid in the ventral pallidum using in vivo microdialysis.
Topics: Animals; Baclofen; Calcium Channels; Dialysis; Dose-Response Relationship, Drug; Extracellular Space; gamma-Aminobutyric Acid; Globus Pallidus; Magnesium Chloride; Male; Muscimol; Neurons; Potassium; Rats; Rats, Inbred Strains; Sodium Channels; Tetrodotoxin; Verapamil; Veratridine | 1992 |
The role of GABA in inhibitory synaptic inputs on inhibitory burst neurons in the cat.
Topics: Animals; Bicuculline; Cats; gamma-Aminobutyric Acid; Glycine; Iontophoresis; Muscimol; Neurons; Nystagmus, Physiologic; Receptors, GABA-A; Serotonin; Synapses; Vestibular Nuclei | 1992 |
Changes in the effect of gamma-aminobutyric acid on prolactin secretion during sexual maturation in female rats.
Topics: 4-Aminobutyrate Transaminase; Aging; Aminooxyacetic Acid; Animals; Baclofen; Female; gamma-Aminobutyric Acid; Hypothalamus; Muscimol; Prolactin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sexual Maturation | 1992 |
Regulation of somatodendritic dopamine release in the ventral tegmental area by opioids and GABA: an in vivo microdialysis study.
Topics: Afferent Pathways; Animals; Baclofen; Biological Transport; Dendrites; Dialysis; Dopamine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Interneurons; Kinetics; Male; Models, Neurological; Morphine; Muscimol; Naloxone; Neurons; Rats; Rats, Inbred Strains; Receptors, GABA-A; Tegmentum Mesencephali; Time Factors | 1992 |
Muscimol and N,N-dimethylmuscimol: from a GABA agonist to a glycine antagonist.
Topics: Chemical Phenomena; Chemistry, Physical; Computer Simulation; gamma-Aminobutyric Acid; Glycine; Isoxazoles; Models, Molecular; Molecular Structure; Muscimol; Receptors, GABA-A; Receptors, Glycine; Receptors, Neurotransmitter; Structure-Activity Relationship | 1992 |
Functionally relevant gamma-aminobutyric acidA receptors: equivalence between receptor affinity (Kd) and potency (EC50)?
Topics: Animals; Binding Sites; Cerebral Cortex; Chloride Channels; Chlorides; Ethylmaleimide; gamma-Aminobutyric Acid; Ion Channel Gating; Kinetics; Male; Membrane Proteins; Muscimol; Neurons; Radioisotopes; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes; Tritium | 1992 |
Alfaxalone, pentobarbital and diazepam potentiate gamma-aminobutyric acid-induced depolarizations in single myenteric neurons of guinea pig intestine.
Topics: Anesthetics; Animals; Diazepam; Drug Synergism; gamma-Aminobutyric Acid; Guinea Pigs; Hydrocortisone; Intestines; Male; Membrane Potentials; Muscimol; Pentobarbital; Pregnanediones; Receptors, GABA-A | 1992 |
GABAergic influence on the development of the sexually dimorphic nucleus of male and female rats.
Topics: Animals; Female; gamma-Aminobutyric Acid; Hypothalamus; Luteinizing Hormone; Male; Muscimol; Neurons; Pregnancy; Prolactin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sex Characteristics | 1992 |
The GABAA-like autoreceptor is a pharmacologically novel GABA receptor.
Topics: Animals; Cerebral Cortex; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Norepinephrine; Rats; Receptors, GABA-A | 1992 |
Inhibition of GABA-gated chloride channel function by arachidonic acid.
Topics: Animals; Arachidonic Acid; Cerebral Cortex; Chloride Channels; Chlorides; Fatty Acids; gamma-Aminobutyric Acid; Indomethacin; Ion Channel Gating; Male; Membrane Proteins; Muscimol; Phospholipases A; Phospholipases A2; Rats; Rats, Inbred Strains; Synaptosomes | 1992 |
Immortalized hypothalamic GT1-7 neurons express functional gamma-aminobutyric acid type A receptors.
Topics: Anesthetics; Animals; Barbiturates; Base Sequence; Bicuculline; Cell Line, Transformed; Cell Membrane; Chloride Channels; Diazepam; Electrophysiology; Flunitrazepam; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation; Hypothalamus; Membrane Proteins; Mice; Molecular Sequence Data; Muscimol; Neurons; Peptides; Polymerase Chain Reaction; Receptors, GABA-A; RNA, Messenger; Sensitivity and Specificity; Steroids; Tritium; Tumor Cells, Cultured; Zinc | 1992 |
Antiaversive action of benzodiazepines on escape behavior induced by electrical stimulation of the inferior colliculus.
Topics: Animals; Arousal; Avoidance Learning; Brain Mapping; Dose-Response Relationship, Drug; Electric Stimulation; Escape Reaction; gamma-Aminobutyric Acid; Inferior Colliculi; Male; Midazolam; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sensory Thresholds; Synaptic Transmission | 1992 |
Ro 15-4513 binding to GABAA receptors: subunit composition determines ligand efficacy.
Topics: Animals; Azides; Benzodiazepines; Binding, Competitive; Brain; Cerebellum; Diazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Ligands; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1992 |
Functional alterations in cerebral GABAA receptor complex associated with formation of alcohol dependence: analysis using GABA-dependent 36Cl- influx into neuronal membrane vesicles.
Topics: Administration, Inhalation; Alcohol Withdrawal Delirium; Alcoholism; Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Flunitrazepam; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred Strains; Muscimol; Neurons; Radioligand Assay; Receptors, GABA-A; Synaptic Membranes; Synaptic Vesicles | 1992 |
Age-dependent changes in substantia nigra GABA-mediated seizure suppression.
Topics: Aging; Animals; Animals, Newborn; Baclofen; Bicuculline; Dominance, Cerebral; Energy Metabolism; Flurothyl; gamma-Aminobutyric Acid; Muscimol; Rats; Receptors, GABA-A; Seizures; Status Epilepticus; Stereotyped Behavior; Substantia Nigra; Synaptic Transmission | 1992 |
GABA, acting at both GABAA and GABAB receptors, inhibits the release of cholecystokinin-like material from the rat spinal cord in vitro.
Topics: Animals; Baclofen; Cholecystokinin; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Perfusion; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Spinal Cord | 1992 |
GABAergic mediation of indirect transsynaptic control over basal and spatial memory testing-induced activation of septo-hippocampal cholinergic activity in mice.
Topics: Animals; Bicuculline; Brain Mapping; Cholinergic Fibers; Discrimination Learning; Dose-Response Relationship, Drug; Exploratory Behavior; gamma-Aminobutyric Acid; Hippocampus; Injections; Male; Mental Recall; Mice; Mice, Inbred BALB C; Muscimol; Neural Pathways; Orientation; Receptors, GABA-A; Retention, Psychology; Septum Pellucidum; Space Perception; Substantia Innominata; Synapses; Synaptic Transmission | 1992 |
Changes in ligand binding to GABAA receptor sites in pacific salmon (Oncorhynchus) brain during spawning migration and "aging".
Topics: Aging; Aminobutyrates; Analgesics; Animals; Baclofen; Bicuculline; Binding, Competitive; Brain; Female; gamma-Aminobutyric Acid; Isoxazoles; Kinetics; Ligands; Male; Muscimol; Receptors, GABA-A; Salmon; Sexual Behavior, Animal | 1992 |
Participation of GABAergic systems in the production of antinociception by various stresses in mice.
Topics: Analgesia; Animals; Baclofen; Bicuculline; Dose-Response Relationship, Drug; Electroshock; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred Strains; Muscimol; Organophosphorus Compounds; Picrotoxin; Receptors, GABA-A; Stress, Psychological | 1992 |
Isolation and characterization of endogenous modulators for GABA system.
Topics: Animals; Brain Chemistry; Cations, Divalent; Cell Membrane; Drug Stability; Flunitrazepam; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamates; Glutamic Acid; Hot Temperature; Hydrogen-Ion Concentration; Molecular Weight; Muscimol; Pyrrolidonecarboxylic Acid; Swine | 1992 |
GABA inhibits ACh release from the rabbit retina: a direct effect or feedback to bipolar cells?
Topics: Acetylcholine; Animals; Excitatory Amino Acid Antagonists; Feedback; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Light; Male; Muscimol; Neurons; Quinoxalines; Rabbits; Retina | 1992 |
GABA- and glutamate-activated currents in glial cells of the mouse corpus callosum slice.
Topics: Action Potentials; Animals; Bicuculline; Chloride Channels; Corpus Callosum; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Ion Channel Gating; Kainic Acid; Membrane Proteins; Mice; Muscimol; Oligodendroglia; Pentobarbital; Potassium Channels; Receptors, GABA-A; Receptors, Glutamate; Receptors, Neurotransmitter; Stem Cells | 1992 |
GABAergic influences on somatostatin secretion from hypothalamic neurons cultured in defined medium.
Topics: Animals; Baclofen; Bicuculline; Cells, Cultured; Culture Media; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus; Muscimol; Neurons; Nipecotic Acids; Rats; Receptors, GABA-A; Somatostatin | 1992 |
Cross-talk between excitatory and inhibitory amino acids in the regulation of luteinizing hormone-releasing hormone secretion.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Baclofen; Bicuculline; Drug Interactions; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Gonadotropin-Releasing Hormone; In Vitro Techniques; Male; Median Eminence; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1992 |
Neurotransmitter receptors involved in post-training memory processing by the amygdala, medial septum, and hippocampus of the rat.
Topics: Amygdala; Animals; Avoidance Learning; Behavior, Animal; Exploratory Behavior; gamma-Aminobutyric Acid; Habituation, Psychophysiologic; Hippocampus; Male; Memory; Muscimol; Neurotransmitter Agents; Prostheses and Implants; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Research Design; Retention, Psychology | 1992 |
Effect of nucleus tractus solitarius lesions on cardiovascular responses elicited from the caudal ventrolateral medulla.
Topics: Animals; Blood Pressure; Denervation; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Homeostasis; Male; Medulla Oblongata; Muscimol; Neural Pathways; Pressoreceptors; Rabbits | 1992 |
Age-dependent regulation of GABAA receptors in neocortex.
Topics: Aging; Animals; Baclofen; Cats; Cerebral Cortex; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kinetics; Muscimol; Pyridazines; Rats; Rats, Wistar; Receptors, GABA-A; Veratridine | 1992 |
Influence of extracellular and intracellular pH on GABA-gated chloride conductance in crayfish muscle fibres.
Topics: Animals; Astacoidea; Chloride Channels; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Ion Channels; Kinetics; Membrane Potentials; Membrane Proteins; Muscimol; Muscles | 1992 |
Effect of thiol group modification on ion flux and ligand binding properties of the GABAA-benzodiazepine receptor chloride channel complex.
Topics: Animals; Chlorides; Chlorine; Diazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Male; Mice; Mice, Inbred ICR; Muscimol; Radioisotopes; Receptors, GABA-A; Sulfhydryl Compounds; Sulfhydryl Reagents | 1992 |
Vasoactive intestinal polypeptide modulates GABAA receptor function in bipolar cells and ganglion cells of the rat retina.
Topics: Aging; Animals; Animals, Newborn; Chloride Channels; Drug Synergism; Electric Conductivity; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Kinetics; Membrane Potentials; Membrane Proteins; Muscimol; Rats; Receptors, GABA-A; Retina; Retinal Ganglion Cells; Time Factors; Vasoactive Intestinal Peptide | 1992 |
gamma-Aminobutyric acid, through GABAA receptors, inhibits the potassium-stimulated release of calcitonin gene-related peptide- but not that of substance P-like material from rat spinal cord slices.
Topics: Animals; Baclofen; Bicuculline; Calcitonin Gene-Related Peptide; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Potassium; Rats; Rats, Inbred Strains; Receptors, GABA-A; Spinal Cord; Substance P | 1992 |
m-Sulfonate benzene diazonium chloride: a powerful affinity label for the gamma-aminobutyric acid binding site from rat brain.
Topics: Affinity Labels; Animals; Binding Sites; Brain; Diazonium Compounds; gamma-Aminobutyric Acid; Ligands; Muscimol; Rats; Rats, Wistar; Sulfanilic Acids; Synaptosomes | 1992 |
GABAergic inhibition of neuronal activity in the primate motor and premotor cortex during voluntary movement.
Topics: Animals; Bicuculline; gamma-Aminobutyric Acid; Iontophoresis; Macaca; Macaca mulatta; Motor Cortex; Movement; Muscimol; Neural Inhibition; Neurons; Volition | 1992 |
[Spatial similarity between crystal cells of various agonists of amino acid receptors and the biological effects of these substances].
Topics: Crystallization; gamma-Aminobutyric Acid; Glycine; Muscimol; Receptors, Amino Acid; Taurine | 1992 |
Inward current caused by sodium-dependent uptake of GABA in the crayfish stretch receptor neurone.
Topics: Animals; Astacoidea; Chlorides; gamma-Aminobutyric Acid; Ion Channel Gating; Mechanoreceptors; Membrane Potentials; Muscimol; Neurons; Sodium | 1992 |
Inactivation of the DSCF area of the auditory cortex with muscimol disrupts frequency discrimination in the mustached bat.
Topics: Acoustic Stimulation; Animals; Auditory Cortex; Brain Mapping; Chiroptera; Discrimination, Psychological; Doppler Effect; Electrophysiology; Electroshock; Female; gamma-Aminobutyric Acid; Hearing; Injections; Leg; Male; Muscimol; Somatosensory Cortex | 1992 |
Effect of gamma-aminobutyric acid and muscimol on corticosterone secretion in rats.
Topics: Animals; Atropine; Bicuculline; Corticosterone; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Injections, Intraventricular; Male; Muscimol; Rats; Rats, Wistar | 1992 |
All indoleamine-accumulating cells in the rabbit retina contain GABA.
Topics: 5,7-Dihydroxytryptamine; Animals; Autoradiography; Biogenic Monoamines; Female; gamma-Aminobutyric Acid; Immunohistochemistry; Indoles; Male; Muscimol; Oxidation-Reduction; Photochemistry; Photoreceptor Cells; Rabbits; Retina | 1992 |
Baclofen reverses the hypersensitivity of dorsal horn wide dynamic range neurons to mechanical stimulation after transient spinal cord ischemia; implications for a tonic GABAergic inhibitory control of myelinated fiber input.
Topics: Animals; Baclofen; Decerebrate State; Electric Stimulation; gamma-Aminobutyric Acid; Ischemia; Muscimol; Nerve Fibers; Nerve Fibers, Myelinated; Neurons; Physical Stimulation; Rats; Rats, Inbred Strains; Spinal Cord | 1992 |
Effects of alcohol dependence on shock-induced fighting: action of muscimol and homotaurine.
Topics: Aggression; Alcoholism; Animals; Body Weight; Electroshock; Ethanol; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rats, Inbred Strains; Taurine | 1992 |
Influence of GABA on gonadotrophin release in the goldfish.
Topics: 4-Aminobutyrate Transaminase; Aminocaproates; Animals; Baclofen; Brain; Estradiol; gamma-Aminobutyric Acid; Goldfish; Gonadotropins, Pituitary; Hypothalamus; Immunohistochemistry; Muscimol; Pituitary Gland; Seasons; Telencephalon; Testosterone; Vigabatrin | 1992 |
Tonic activity of rat medial vestibular nucleus neurones in vitro and its inhibition by GABA.
Topics: Action Potentials; Animals; Baclofen; Cobalt; Dose-Response Relationship, Drug; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Neurons; Nipecotic Acids; Picrotoxin; Proline; Rats; Rats, Inbred Strains; Vestibular Nuclei | 1992 |
gamma-Aminobutyric acid-induced response in rat dissociated paratracheal ganglion cells.
Topics: Animals; Chlorides; Diazepam; Drug Synergism; Electric Conductivity; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia; Muscimol; Pentobarbital; Rats; Rats, Inbred Strains; Trachea | 1992 |
Oculomotor effects of gamma-aminobutyric acid agonists and antagonists in the vestibular nuclei of the alert monkey.
Topics: Animals; Bicuculline; Darkness; Eye Movements; GABA Antagonists; gamma-Aminobutyric Acid; Light; Macaca fascicularis; Muscimol; Nystagmus, Physiologic; Reflex, Vestibulo-Ocular; Saccades; Vestibular Nuclei | 1992 |
Disruptive effects of muscimol infused into the basal forebrain on conditional discrimination and visual attention: differential interactions with cholinergic mechanisms.
Topics: Animals; Attention; Bicuculline; Discrimination Learning; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Injections; Male; Muscimol; Parasympathetic Nervous System; Physostigmine; Prosencephalon; Quisqualic Acid; Rats; Reaction Time | 1992 |
Involvement of GABAergic mechanisms in chloroquine-induced seizures in mice.
Topics: Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Chloroquine; Diazepam; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Phenobarbital; Seizures | 1992 |
GABA agonists and omega conotoxin GVIA modulate responses to nerve activation of the perfused rat mesentery.
Topics: Animals; Baclofen; Calcium Channels; Electric Stimulation; gamma-Aminobutyric Acid; Male; Mesenteric Arteries; Muscimol; omega-Conotoxin GVIA; Peptides, Cyclic; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sympathetic Nervous System; Vasoconstriction; Vasodilation | 1991 |
GABAA and GABAB receptor-mediated effects on the spontaneous activity of the longitudinal layer in cat terminal ileum.
Topics: Animals; Baclofen; Bicuculline; Cats; GABA Antagonists; gamma-Aminobutyric Acid; Gastrointestinal Motility; Ileum; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Picrotoxin; Receptors, GABA-A; Sesterterpenes; Tetrodotoxin | 1991 |
2-amino-4-phosphonobutyric acid exerts a light-dependent effect on post-gabaculine levels of retinal gamma-aminobutyric acid (GABA): evidence that ON synaptic pathways regulate retinal GABAergic transmission.
Topics: Aminobutyrates; Animals; Bicuculline; Cyclohexanecarboxylic Acids; gamma-Aminobutyric Acid; Kainic Acid; Light; Male; Muscimol; Neural Pathways; Rats; Rats, Inbred Strains; Retina; Synapses; Synaptic Transmission; Veratridine | 1991 |
Opioid and prostaglandin mechanisms involved in the effects of GABAergic drugs on body temperature.
Topics: Animals; Baclofen; Bicuculline; Body Temperature; Dose-Response Relationship, Drug; Endorphins; gamma-Aminobutyric Acid; Indomethacin; Injections, Intraperitoneal; Muscimol; Naloxone; Prostaglandins; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1991 |
gamma-Aminobutyric acid-activated chloride channels in rats selectively bred for differential acute sensitivity to alcohol.
Topics: Alcohol Drinking; Animals; Chloride Channels; Diazepam; Female; Flunitrazepam; gamma-Aminobutyric Acid; Membrane Proteins; Muscimol; Pentobarbital; Phenobarbital; Phenotype; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Selection, Genetic | 1991 |
Induction of food intake by a GABAergic mechanism in the turkey.
Topics: Animals; Brain; Brain Mapping; Dose-Response Relationship, Drug; Drinking Behavior; Feeding Behavior; gamma-Aminobutyric Acid; Muscimol; Paraventricular Hypothalamic Nucleus; Picrotoxin; Receptors, GABA-A; Substantia Nigra; Turkeys; Ventromedial Hypothalamic Nucleus | 1991 |
Evidence for a critical role of GABAergic transmission within the thalamus in the genesis and control of absence seizures in the rat.
Topics: Aminocaproates; Animals; Anticonvulsants; Disease Models, Animal; Electroencephalography; Epilepsy, Absence; Evoked Potentials; gamma-Aminobutyric Acid; Male; Membrane Potentials; Microinjections; Muscimol; Rats; Rats, Inbred Strains; Reference Values; Stereotaxic Techniques; Synaptic Transmission; Thalamus; Vigabatrin | 1991 |
Lack of proconvulsant action of GABA depletion in substantia nigra in several seizure models.
Topics: Animals; Bicuculline; Cerebral Cortex; gamma-Aminobutyric Acid; Isoniazid; Kainic Acid; Male; Microinjections; Muscimol; Pilocarpine; Rats; Rats, Inbred Strains; Seizures; Substantia Nigra; Synaptic Transmission | 1991 |
Inhibition of calcium influx and calcium current by gamma-aminobutyric acid in single synaptic terminals.
Topics: Animals; Baclofen; Calcium; Calcium Channels; Electric Conductivity; gamma-Aminobutyric Acid; Goldfish; In Vitro Techniques; Membrane Potentials; Muscimol; Neurons; Picrotoxin; Retina; Synapses | 1991 |
3-Thienyl- and 3-furylaminobutyric acids. Synthesis and binding GABAB receptor studies.
Topics: Animals; Baclofen; Binding, Competitive; Brain; Chemical Phenomena; Chemistry; Furans; gamma-Aminobutyric Acid; Molecular Structure; Muscimol; Rats; Receptors, GABA-A; Synaptic Membranes; Thiophenes | 1991 |
Avian locomotion activated by brainstem infusion of neurotransmitter agonists and antagonists. II. gamma-Aminobutyric acid.
Topics: Animals; Brain Stem; Ducks; Electric Stimulation; gamma-Aminobutyric Acid; Geese; Motor Activity; Muscimol; Picrotoxin; Receptors, GABA-A; Reticular Formation | 1991 |
Adult-like biphasic neurobehavioral changes induced by a GABA-A agonist in infant and weanling mice.
Topics: Aging; Animals; Animals, Newborn; Ataxia; Behavior, Animal; Catalepsy; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred Strains; Motor Activity; Muscimol; Nervous System Physiological Phenomena; Receptors, GABA-A | 1991 |
Why are most GABA agonists not effective antiepileptic drugs?
Topics: Animals; Anticonvulsants; Bicuculline; Cats; Electroencephalography; GABA Antagonists; gamma-Aminobutyric Acid; Isoxazoles; Muscimol; Receptors, GABA-A; Synaptic Transmission; Trigeminal Nucleus, Spinal | 1991 |
The mismatch problem for GABAergic amacrine cells in goldfish retina: resolution and other issues.
Topics: 4-Aminobutyrate Transaminase; Animals; Autoradiography; Biomarkers; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Goldfish; Immunohistochemistry; Muscimol; Neurons; Receptors, GABA-A; Retina | 1991 |
Regulation of the GABAA receptor/ion channel complex by intracellular GABA levels.
Topics: Aminocaproates; Animals; Cerebral Cortex; Chloride Channels; Chlorides; Cyclohexanecarboxylic Acids; gamma-Aminobutyric Acid; Hydrazines; Isoniazid; Male; Membrane Proteins; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes; Vigabatrin | 1991 |
Sexual maturation modifies the GABAergic control of gonadotrophin secretion in female rats.
Topics: Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Female; Follicle Stimulating Hormone; gamma-Aminobutyric Acid; Gonadotropins; Luteinizing Hormone; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sexual Maturation | 1991 |
Reduction in bioelectric GABA and NMDA responses in organotypic neocortical explants by chronic elevation of potassium.
Topics: Action Potentials; Animals; Animals, Newborn; Cell Membrane; Cerebral Cortex; Dizocilpine Maleate; gamma-Aminobutyric Acid; Membrane Potentials; Muscimol; N-Methylaspartate; Neurons; Organ Culture Techniques; Potassium; Rats; Receptors, GABA-A | 1991 |
Effects of methylazoxymethanol treatment on the GABAergic synaptosomes in the P2 fraction from developing mouse cerebellum.
Topics: Animals; Cerebellum; Flunitrazepam; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Methylazoxymethanol Acetate; Mice; Muscimol; Receptors, GABA-A; Synaptosomes | 1991 |
GABA/BZ-and NMDA-receptor interaction in digoxin-induced convulsions in rats.
Topics: Animals; Baclofen; Diazepam; Digoxin; Dizocilpine Maleate; Female; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Muscimol; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Salts; Seizures | 1991 |
Noradrenaline release in the rat vena cava is inhibited by gamma-aminobutyric acid via GABAB receptors but not affected by histamine.
Topics: Animals; Baclofen; Bicuculline; Corticosterone; Desipramine; Electric Stimulation; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Histamine; In Vitro Techniques; Male; Muscimol; Norepinephrine; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Receptors, GABA-A; Vena Cava, Inferior; Yohimbine | 1991 |
Serotonin modulates muscimol- and baclofen-elicited inhibition of cerebellar Purkinje cells.
Topics: Action Potentials; Animals; Baclofen; Cerebellum; gamma-Aminobutyric Acid; Glycine; Male; Muscimol; Purkinje Cells; Rats; Receptors, GABA-A; Serotonin | 1991 |
Effects of GABAergic and noradrenergic injections into the cerebellar flocculus on vestibulo-ocular reflexes in the rabbit.
Topics: Adaptation, Physiological; Animals; Baclofen; Cerebellum; Female; gamma-Aminobutyric Acid; Isoproterenol; Male; Muscimol; Norepinephrine; Purkinje Cells; Rabbits; Receptors, GABA-A; Reflex, Vestibulo-Ocular; Sotalol; Vestibule, Labyrinth | 1991 |
[The action of GABA agonists and an antagonist on the frequency structure of the electrical activity of different brain formations in rats].
Topics: Animals; Baclofen; Bicuculline; Brain; Electrodes, Implanted; Electroencephalography; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A; Wakefulness | 1991 |
Regulation of gamma-aminobutyric acidA receptor subunit expression by activation of N-methyl-D-aspartate-selective glutamate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Base Sequence; Dizocilpine Maleate; Dose-Response Relationship, Drug; Down-Regulation; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamates; Glutamic Acid; Molecular Sequence Data; Muscimol; N-Methylaspartate; Polymerase Chain Reaction; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Glutamate; Receptors, Neurotransmitter; RNA, Messenger | 1991 |
GABA and glutamate interact in the substantia innominata/lateral preoptic area to modulate locomotor activity.
Topics: 2-Aminoadipic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Ibotenic Acid; Male; Motor Activity; Muscimol; N-Methylaspartate; Picrotoxin; Preoptic Area; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Glutamate; Receptors, Neurotransmitter | 1991 |
GABAmimetic agents display anxiolytic-like effects in the social interaction and elevated plus maze procedures.
Topics: Aminooxyacetic Acid; Animals; Anti-Anxiety Agents; Conflict, Psychological; Diazepam; Exploratory Behavior; gamma-Aminobutyric Acid; Isonicotinic Acids; Isoxazoles; Male; Muscimol; Rats; Rats, Inbred Strains; Social Behavior; Valproic Acid | 1991 |
Involvement of GABAergic systems in benzodiazepine-induced impairment of passive avoidance learning in mice.
Topics: Animals; Anti-Anxiety Agents; Avoidance Learning; Bicuculline; Chlordiazepoxide; Drug Interactions; Flumazenil; GABA Antagonists; gamma-Aminobutyric Acid; Male; Memory; Mice; Mice, Inbred Strains; Muscimol; Picrotoxin | 1991 |
Glycinergic control of [Leu5]enkephalin levels in chicken retina.
Topics: Animals; Baclofen; Chickens; Enkephalin, Leucine; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Isoxazoles; Muscimol; Neurotransmitter Agents; Picrotoxin; Radioimmunoassay; Retina; Strychnine | 1991 |
Characterization and differential regulation of GABAA and benzodiazepine receptors in rat neocortex.
Topics: Animals; Autoradiography; Binding, Competitive; Brain; Cerebral Cortex; Clonazepam; Down-Regulation; Flunitrazepam; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Kinetics; Male; Muscimol; Pyridazines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Tritium; Veratridine | 1991 |
Gamma-aminobutyric acid (GABAB) receptor-mediated inhibition of tyrosine hydroxylase activity in the striatum of rat.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Baclofen; Calcium; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; gamma-Aminobutyric Acid; Hydrazines; In Vitro Techniques; Male; Muscimol; Neural Pathways; Picrotoxin; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, GABA-A; Substantia Nigra; Tyrosine 3-Monooxygenase | 1991 |
Effects of dihydroavermectin B1a and analogs on stretcher muscle of the lined shore crab, Pachygrapsus crassipes.
Topics: Animals; Anthelmintics; Bicuculline; Brachyura; Caenorhabditis; Chlorides; Cobalt; Dose-Response Relationship, Drug; Drug Interactions; gamma-Aminobutyric Acid; In Vitro Techniques; Ivermectin; Membrane Potentials; Membranes; Motor Endplate; Muscimol; Muscles; Picrotoxin; Sesterterpenes; Structure-Activity Relationship; Synapses; Time Factors | 1991 |
The effect of medetomidine on GABA and benzodiazepine receptors in vivo: lack of anxiolytic but some evidence of possible stress-protective activity.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Bicuculline; Brain; Cerebral Cortex; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Imidazoles; Kidney; Male; Medetomidine; Muscimol; Myocardium; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures; Stimulation, Chemical; Stress, Physiological; Tritium | 1991 |
The entopeduncular nucleus regulates muscle tone in genetically spastic rats: role of substance P and gamma-aminobutyric acid.
Topics: Animals; Female; gamma-Aminobutyric Acid; Globus Pallidus; Male; Muscimol; Muscle Spasticity; Muscle Tonus; Rats; Rats, Inbred Strains; Substance P | 1990 |
Chronic central GABAergic stimulation attenuates hypothalamic hyperactivity and development of spontaneous hypertension in rats.
Topics: Animals; Blood Pressure; Electric Stimulation; gamma-Aminobutyric Acid; Heart Rate; Hemodynamics; Hypertension; Hypothalamus; Injections; Injections, Intraventricular; Male; Muscimol; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sympathetic Nervous System; Valproic Acid | 1990 |
GABAergic modulation of catecholamine release from cultured bovine adrenal chromaffin cells. Evidence for the involvement of Cl(-)-dependent Ca2+ entry.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Adrenal Glands; Animals; Calcium; Calcium Radioisotopes; Catecholamines; Cattle; Cells, Cultured; Chlorides; Chromaffin System; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Ion Channels; Muscimol; Pentobarbital; Time Factors; Veratridine | 1990 |
GABAA receptor-mediated increase in membrane chloride conductance in rat paratracheal neurones.
Topics: Animals; Bicuculline; Cell Membrane; Chlorides; Electrophysiology; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Membrane Potentials; Muscimol; Neurons; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Tetrodotoxin; Trachea | 1990 |
Activation of subconductance states by gamma-aminobutyric acid and its analogs in chick cerebral neurons.
Topics: Analgesics; Animals; Cells, Cultured; Cerebral Cortex; Chick Embryo; Chlorides; Electric Conductivity; gamma-Aminobutyric Acid; Ion Channel Gating; Ion Channels; Isonicotinic Acids; Isoxazoles; Muscimol; Neurons | 1990 |
Electrical and chemical excitability appear one week before birth in the embryonic rat spinal cord.
Topics: Animals; Electric Stimulation; Female; Fetus; Flow Cytometry; Fluorescence; gamma-Aminobutyric Acid; Kainic Acid; Light; Membrane Potentials; Muscimol; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Scattering, Radiation; Sodium Channels; Spinal Cord; Staining and Labeling; Stimulation, Chemical; Veratridine | 1990 |
GABA affects the glutamate receptor-chloride channel complex in mechanically isolated and internally perfused Aplysia neurons.
Topics: Animals; Anura; Aplysia; Baclofen; Chlorides; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Muscimol; Neurons; Perfusion; Receptors, Glutamate; Receptors, Neurotransmitter | 1990 |
Pharmacological evidence indicating a role of GABAergic systems in termination of limbic seizures.
Topics: Animals; Baclofen; Bicuculline; Chloride Channels; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Ion Channels; Limbic System; Male; Membrane Proteins; Muscimol; Neural Inhibition; Picrotoxin; Rats; Seizures | 1990 |
Site-specific acylation of GABA-gated Cl- channels: effects on 36Cl- uptake.
Topics: Acylation; Animals; Biological Transport, Active; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Chlorides; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Ligands; Male; Membrane Proteins; Muscimol; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes | 1991 |
Postembedding immunocytochemistry for GABA and glycine reveals the synaptic relationships of the dopaminergic amacrine cell of the cat retina.
Topics: Animals; Cats; Dopamine; gamma-Aminobutyric Acid; Glycine; Immunohistochemistry; Microscopy, Electron; Muscimol; Plastic Embedding; Retina; Staining and Labeling; Synapses; Tyrosine 3-Monooxygenase | 1991 |
Melatonin interaction with the benzodiazepine-GABA receptor complex in the CNS.
Topics: Animals; Anti-Anxiety Agents; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cerebral Cortex; Chlorides; Diazepam; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Ion Channels; Melatonin; Muscimol; Prosencephalon; Rats; Receptors, GABA-A; Serotonin; Synaptosomes | 1991 |
Quinolones and fenbufen interact with GABAA receptor in dissociated hippocampal cells of rat.
Topics: 4-Quinolones; Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Chloride Channels; Drug Interactions; Electrophysiology; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Ion Channels; Membrane Proteins; Muscimol; Neurons; Pentobarbital; Phenylbutyrates; Pyramidal Tracts; Rats; Rats, Inbred Strains; Receptors, GABA-A; Structure-Activity Relationship | 1991 |
Regulation of cardiovascular sympathetic neurons by substance P and gamma-aminobutyric acid in the rat spinal cord.
Topics: Animals; Baclofen; Bicuculline; Blood Pressure; Capsaicin; Cardiovascular Physiological Phenomena; Cardiovascular System; Catecholamines; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glycine; Heart Rate; Injections, Spinal; Male; Muscimol; Neurons; Neuropeptide Y; Rats; Rats, Inbred Strains; Receptors, GABA-A; Spinal Cord; Substance P; Sympathetic Nervous System | 1991 |
Increased intracellular gamma-aminobutyric acid selectively lowers the level of the larger of two glutamate decarboxylase proteins in cultured GABAergic neurons from rat cerebral cortex.
Topics: 4-Aminobutyrate Transaminase; Amino Acids; Aminocaproates; Animals; Baclofen; Cells, Cultured; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Immunoblotting; Intracellular Membranes; Muscimol; Neurons; Rats; Vigabatrin | 1992 |
Possible mediation of GABA induced growth hormone secretion by increased calcium-flux in neonatal pituitaries.
Topics: Animals; Animals, Newborn; Calcium; Female; gamma-Aminobutyric Acid; Growth Hormone; Male; Muscimol; Nifedipine; Picrotoxin; Pituitary Gland; Potassium; Rats; Thyrotropin-Releasing Hormone | 1992 |
A re-appraisal of the role of layer VI of the visual cortex in the generation of cortical end inhibition.
Topics: Animals; Brain Mapping; Cats; Female; gamma-Aminobutyric Acid; Iontophoresis; Kinetics; Male; Muscimol; Time Factors; Visual Cortex | 1991 |
Action of gamma-aminobutyric acid (GABA) in the isolated photosensory pineal organ.
Topics: Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Immunohistochemistry; In Vitro Techniques; Kinetics; Light; Muscimol; Neurons; Photic Stimulation; Picrotoxin; Pineal Gland; Time Factors; Trout | 1991 |
Pharmacological and biochemical properties of the gamma-aminobutyric acid-benzodiazepine receptor protein from codfish brain.
Topics: Animals; Benzodiazepines; Binding, Competitive; Brain; Dose-Response Relationship, Drug; Fishes; Flunitrazepam; gamma-Aminobutyric Acid; Ivermectin; Kinetics; Muscimol; Receptors, GABA-A; Tritium | 1991 |
Pharmacologic characterization of GABAA/benzodiazepine receptor in rat hippocampus during aging.
Topics: Aging; Animals; Binding Sites; Cerebellum; Cerebral Cortex; Culture Techniques; Drug Interactions; Flunitrazepam; gamma-Aminobutyric Acid; Hippocampus; Male; Muscimol; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1991 |
cAMP analogs inhibit gamma-aminobutyric acid-gated chloride flux and activate protein kinase A in brain synaptoneurosomes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Cell Compartmentation; Cerebral Cortex; Chloride Channels; Cyclic AMP; Enzyme Activation; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Proteins; Muscimol; Protein Kinases; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes | 1991 |
Characterization of recombinant GABAA receptors produced in transfected cells from murine alpha 1, beta 1, and gamma 2 subunit cDNAs.
Topics: Animals; Binding Sites; Cell Line; DNA; Electrophysiology; Flunitrazepam; gamma-Aminobutyric Acid; Humans; Ligands; Mice; Muscimol; Receptors, GABA-A; Recombinant Proteins; Transfection | 1991 |
GABAergic control of receptivity in the female rat.
Topics: Animals; Cerebral Cortex; Estradiol; Female; gamma-Aminobutyric Acid; Hypothalamus; Muscimol; Ovariectomy; Posture; Preoptic Area; Progesterone; Rats; Rats, Inbred Strains; Sexual Behavior, Animal | 1991 |
Behavioral deficits induced by local injection of bicuculline and muscimol into the primate motor and premotor cortex.
Topics: Animals; Behavior, Animal; Bicuculline; Electromyography; gamma-Aminobutyric Acid; Injections; Iontophoresis; Macaca; Macaca mulatta; Motor Cortex; Muscimol; Muscles; Psychomotor Performance; Reaction Time | 1991 |
Amygdala and dorsal hippocampus lesions block the effects of GABAergic drugs on memory storage.
Topics: Amygdala; Animals; Bicuculline; gamma-Aminobutyric Acid; Hippocampus; Male; Memory; Mice; Mice, Inbred Strains; Muscimol; Reaction Time; Retention, Psychology | 1991 |
gamma-Aminobutyric acid localization and function as modulator of cholinergic neurotransmission in rat antral mucosal/submucosal fragments.
Topics: Acetylcholine; Animals; Autoradiography; Digestive System; Epithelial Cells; Epithelium; gamma-Aminobutyric Acid; Gastric Mucosa; Glutamate Decarboxylase; Immunohistochemistry; In Vitro Techniques; Intestinal Mucosa; Male; Muscimol; Pyloric Antrum; Rats; Rats, Inbred Strains | 1991 |
Presence of a highly efficient "binding" to bacterial contamination can distort data from binding studies.
Topics: Animals; Cats; Cerebral Cortex; GABA Antagonists; gamma-Aminobutyric Acid; Gram-Positive Bacteria; Isonicotinic Acids; Muscimol; Nipecotic Acids; Proline; Pyridazines; Radioligand Assay; Receptors, GABA-A; Tritium | 1990 |
Effects of anticonvulsants and gamma-aminobutyric acid (GABA)-mimetic drugs on immunoreactive somatostatin and GABA contents in the rat brain.
Topics: Aminooxyacetic Acid; Animals; Anticonvulsants; Brain Chemistry; Carbamazepine; Chromatography, Gel; Drug Interactions; Ethanolamines; gamma-Aminobutyric Acid; Male; Muscimol; Phenytoin; Rats; Rats, Inbred Strains; Somatostatin; Valproic Acid | 1990 |
Effects of GABA and anxiolytics on the single unit discharge of suprachiasmatic neurons in rat hypothalamic slices.
Topics: Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Baclofen; Bicuculline; Diazepam; Flunitrazepam; gamma-Aminobutyric Acid; Hypothalamus; In Vitro Techniques; Muscimol; Neurons; Piperazines; Rats; Receptors, GABA-A; Suprachiasmatic Nucleus | 1990 |
Gamma-aminobutyric acid enhancement of potassium-stimulated release of [3H]norepinephrine by multiple mechanisms in rat cortical slices.
Topics: Animals; Calcimycin; Dose-Response Relationship, Drug; Drug Synergism; Frontal Lobe; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Norepinephrine; Potassium; Rats; Rats, Inbred Strains; Tritium | 1991 |
GABA mediated inhibition of abdominal postural flexion in lobster.
Topics: Abdomen; Animals; Baclofen; Bicuculline; Drug Interactions; gamma-Aminobutyric Acid; Ganglia; Interneurons; Muscimol; Nephropidae; Physical Stimulation; Picrotoxin; Posture; Reflex | 1991 |
gamma-Aminobutyric acid-induced response in acutely isolated nucleus solitarii neurons of the rat.
Topics: Animals; Bicuculline; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Medulla Oblongata; Membrane Potentials; Muscimol; Neurons; Penicillin G; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Strychnine | 1991 |
GABAergic control of basal forebrain cholinergic neurons and memory.
Topics: Animals; Conditioning, Operant; Discrimination, Psychological; gamma-Aminobutyric Acid; Injections; Male; Memory; Muscimol; Neurons; Parasympathetic Nervous System; Physostigmine; Rats; Rats, Inbred Strains; Stereotaxic Techniques; Substantia Innominata | 1991 |
Cholinergic amacrine cells in the rabbit retina accumulate muscimol.
Topics: Acetylcholine; Animals; Autoradiography; Cholinergic Fibers; gamma-Aminobutyric Acid; Indoles; Muscimol; Rabbits; Retina; Retinal Ganglion Cells; Tissue Distribution; Trypanocidal Agents | 1991 |
Molecular parameters of three GABA-ergic agonists.
Topics: gamma-Aminobutyric Acid; Models, Molecular; Molecular Structure; Muscimol | 1991 |
Cholinergic nerve terminals of human cerebral cortex possess a GABA transporter whose activation induces release of acetylcholine.
Topics: Acetylcholine; Anticonvulsants; Baclofen; Bicuculline; Biotransformation; Carrier Proteins; Cerebral Cortex; Choline; Female; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Male; Membrane Proteins; Membrane Transport Proteins; Middle Aged; Muscimol; Nerve Endings; Nerve Tissue Proteins; Nipecotic Acids; Organic Anion Transporters; Parasympathetic Nervous System; Proline; Synaptosomes | 1991 |
GABA-related feeding control in genetically obese rats.
Topics: Animals; Deoxyglucose; Feeding Behavior; Female; gamma-Aminobutyric Acid; Hypothalamic Area, Lateral; Hypothalamus; Muscimol; Obesity; Picrotoxin; Rats; Rats, Zucker; Stereotaxic Techniques; Ventromedial Hypothalamic Nucleus | 1991 |
GABAergic control of rubral single unit activity during a reaction time task.
Topics: Animals; Bicuculline; Cats; gamma-Aminobutyric Acid; Microinjections; Motor Activity; Muscimol; Neurons; Reaction Time; Red Nucleus | 1991 |
Action of baclofen, GABA and antagonists on the membrane potential of cultured astrocytes of rat spinal cord.
Topics: Animals; Astrocytes; Autoradiography; Baclofen; Bicuculline; Electrophysiology; Female; GABA Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Microelectrodes; Muscimol; Organophosphorus Compounds; Pregnancy; Rats; Spinal Cord | 1990 |
Modification of chloride flux across brain membranes by inhibitory amino acids in developing and adult mice.
Topics: Amino Acids; Animals; Animals, Newborn; beta-Alanine; Brain; Chlorides; gamma-Aminobutyric Acid; Membranes; Mice; Mice, Inbred Strains; Muscimol; Osmolar Concentration; Taurine | 1990 |
Role of gamma-aminobutyric acid in the zona incerta in the control of luteinizing hormone release and ovulation.
Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Aminooxyacetic Acid; Animals; Baclofen; Diencephalon; Estradiol; Female; GABA Antagonists; gamma-Aminobutyric Acid; Luteinizing Hormone; Muscimol; Ovariectomy; Ovulation; Proestrus; Progesterone; Rats; Rats, Inbred Strains | 1990 |
Involvement of the nigral output pathways in the inhibitory control of the substantia nigra over generalized non-convulsive seizures in the rat.
Topics: Animals; Brain; Dopamine; Electroencephalography; GABA Antagonists; gamma-Aminobutyric Acid; Hydroxydopamines; Male; Muscimol; Norepinephrine; Oxidopamine; Picrotoxin; Rats; Rats, Inbred Strains; Seizures; Serotonin; Substantia Nigra | 1990 |
Chronic agonist exposure induces down-regulation and allosteric uncoupling of the gamma-aminobutyric acid/benzodiazepine receptor complex.
Topics: Allosteric Regulation; Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Chick Embryo; Down-Regulation; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Muscimol; Pyridazines; Receptors, GABA-A | 1990 |
Adaptative changes in two indices of enkephalin neuron activity in mouse striatum following GABAergic stimulation.
Topics: Animals; Corpus Striatum; Diazepam; Enkephalins; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Oligopeptides; Protein Precursors; Receptors, GABA-A; RNA, Messenger | 1990 |
GABA terminal autoreceptors in the pars compacta and in the pars reticulata of the rat substantia nigra are GABAB.
Topics: Animals; Anticonvulsants; Baclofen; gamma-Aminobutyric Acid; Male; Muscimol; Nipecotic Acids; Potassium; Rats; Rats, Inbred Strains; Receptors, GABA-A; Substantia Nigra; Synaptosomes; Tritium | 1990 |
Central GABAA excitatory and GABAB inhibitory receptors regulate gastric acid secretion in rats.
Topics: Anesthesia; Animals; Baclofen; Bicuculline; Central Nervous System; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Gastric Acid; Injections, Intraventricular; Male; Muscimol; Pylorus; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1990 |
Stimulation of luteinizing hormone release by gamma-aminobutyric acid (GABA) agonists: mediation by GABAA-type receptors and activation of chloride and voltage-sensitive calcium channels.
Topics: Amino Acid Sequence; Animals; Baclofen; Calcium Channels; Cells, Cultured; Chloride Channels; Chlorides; Female; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Isoxazoles; Luteinizing Hormone; Membrane Proteins; Molecular Sequence Data; Muscimol; Nifedipine; Pituitary Gland, Anterior; Pyridazines; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1990 |
Quantitative analysis of gamma-aminobutyric acid (GABA) receptors of Purkinje cell layer from rat cerebellar slices.
Topics: Animals; Aspartic Acid; Cerebellum; Drug Interactions; Female; gamma-Aminobutyric Acid; Glutamates; In Vitro Techniques; Muscimol; Neurons; Purkinje Cells; Rats; Receptors, GABA-A | 1990 |
Enhancement by GABA of the stimulation-evoked catecholamine release from cultured bovine adrenal chromaffin cells.
Topics: Acetylcholine; Adrenal Glands; Animals; Bicuculline; Caffeine; Calcium; Catecholamines; Cattle; Cells, Cultured; Chromaffin System; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Muscimol; Nicotine; Picrotoxin; Potassium; Receptors, GABA-A; Veratridine | 1990 |
Increased gamma-aminobutyric acid receptor function in the cerebral cortex of myoclonic calves with an hereditary deficit in glycine/strychnine receptors.
Topics: Animals; Benzodiazepines; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cerebral Cortex; Chloride Channels; Chlorides; Chlorine; Diazepam; Female; gamma-Aminobutyric Acid; Ligands; Male; Membrane Proteins; Muscimol; Myoclonus; Radioisotopes; Receptors, GABA-A; Receptors, Glycine; Receptors, Neurotransmitter; Synaptic Membranes | 1990 |
GABAB receptor-mediated inhibition of the neurogenic vasopressor response in the pithed rat.
Topics: Animals; Baclofen; Bicuculline; Blood Pressure; Decerebrate State; Electric Stimulation; gamma-Aminobutyric Acid; Male; Muscimol; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, GABA-A; Taurine; Tubocurarine; Vascular Resistance | 1990 |
Site-specific enhancement of gamma-aminobutyric acid-mediated inhibition of neural activity by ethanol in the rat medial septal area.
Topics: Animals; Bicuculline; Brain; Drug Interactions; Electrophysiology; Ethanol; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rats, Inbred Strains; Synaptic Transmission | 1990 |
Pharmacological characteristics of two different types of inhibitory GABA receptors on Achatina fulica neurones.
Topics: Animals; Baclofen; Bicuculline; Crotonates; Diazepam; Dibenzazepines; Electrophysiology; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Muscimol; Neurons; Pentobarbital; Picrotoxin; Receptors, GABA-A; Snails | 1990 |
Species dependent dual modulation of the benzodiazepine/GABA receptor chloride channel by dihydroergosine.
Topics: Animals; Bicuculline; Brain; Chloride Channels; Diazepam; Ergotamines; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Proteins; Mice; Mice, Inbred CBA; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures; Species Specificity | 1990 |
Na(+)-dependent GABA transport system scavenges endogenous external GABA and prevents desensitization of GABAA receptors in rat cerebrocortical synaptoneurosomes.
Topics: Animals; Cerebral Cortex; Chlorides; gamma-Aminobutyric Acid; Male; Muscimol; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Proline; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sodium; Synaptosomes | 1990 |
Trophic influence of the distal nerve segment on GABAA receptor expression in axotomized adult sensory neurons.
Topics: Animals; Axons; Denervation; Female; gamma-Aminobutyric Acid; Ganglia, Spinal; Ligation; Muscimol; Nerve Crush; Neurons, Afferent; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sciatic Nerve | 1990 |
Cloned GABA receptors are maintained in a stable cell line: allosteric and channel properties.
Topics: Animals; Antibodies, Monoclonal; Barbiturates; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cell Line; Chlorides; Clone Cells; Convulsants; DNA; gamma-Aminobutyric Acid; Membrane Potentials; Muscimol; Neurons; Plasmids; Receptors, GABA-A; Spinal Cord; Transfection | 1990 |
GABAergic inhibition upon auditory response properties of neurons in the dorsal cochlear nucleus of the rat.
Topics: Acoustic Stimulation; Animals; Bicuculline; Cochlea; Cochlear Nerve; gamma-Aminobutyric Acid; Iontophoresis; Male; Mice; Muscimol; Neurons; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1990 |
Involvement of GABA receptors in the regulation of neurite growth in cultured embryonic chick tectum.
Topics: Animals; Axons; Baclofen; Cells, Cultured; Chick Embryo; Culture Media; gamma-Aminobutyric Acid; Isoxazoles; Ligands; Muscimol; Receptors, GABA-A; Superior Colliculi | 1990 |
Endogenous GABA acts on GABAB receptors in nucleus tractus solitarius to increase blood pressure.
Topics: 4-Aminobutyrate Transaminase; Aminocaproates; Animals; Baclofen; Blood Pressure; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Medulla Oblongata; Muscimol; Nipecotic Acids; Proline; Rats; Rats, Inbred Strains; Receptors, GABA-A; Vigabatrin | 1990 |
Involvement of phosphoinositide metabolism in GABA-induced catecholamine release from cultured bovine adrenal chromaffin cells.
Topics: Adrenal Medulla; Animals; Barbiturates; Benzodiazepines; Calcium; Calcium Channel Blockers; Calcium Channels; Catecholamines; Cattle; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Ouabain; Phosphatidylinositols | 1990 |
Effects of intracerebroventricular injection of muscimol or GABA on operant feeding in pigs.
Topics: Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Feeding Behavior; Female; gamma-Aminobutyric Acid; Hypothalamic Area, Lateral; Injections, Intraventricular; Male; Muscimol; Receptors, GABA-A; Swine; Ventromedial Hypothalamic Nucleus | 1990 |
Properties of GABA-activated whole-cell currents in bipolar cells of the rat retina.
Topics: Animals; Baclofen; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Membrane Potentials; Muscimol; Neurons; Rats; Rats, Inbred Strains; Receptors, GABA-A; Retina | 1990 |
On the relationship between noradrenergic stimulatory and GABAergic inhibitory systems in the control of luteinizing hormone secretion in female rats.
Topics: Animals; Bicuculline; Estradiol; Female; gamma-Aminobutyric Acid; Hydroxydopamines; Luteinizing Hormone; Muscimol; Norepinephrine; Ovariectomy; Oxidopamine; Periodicity; Phenoxybenzamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, GABA-A | 1990 |
GABA(B)-related activity involved in synaptic processing of somatosensory information in S1 cortex of the anaesthetized cat.
Topics: Anesthesia; Animals; Baclofen; Bicuculline; Cats; Electric Stimulation; Electrodes; Female; gamma-Aminobutyric Acid; Iontophoresis; Isoxazoles; Male; Muscimol; Neurons; Physical Stimulation; Somatosensory Cortex; Synapses | 1990 |
Electrical activity and feeding correlates of intracranial hypothalamic injection of GABA, muscimol and picrotoxin in the rats.
Topics: Action Potentials; Animals; Drinking Behavior; Feeding Behavior; gamma-Aminobutyric Acid; Hypothalamus; Male; Microinjections; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains | 1990 |
Presynaptic effects of gamma-aminobutyric acid on norepinephrine release and uptake in rat pineal gland.
Topics: Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Male; Muscimol; Norepinephrine; Pineal Gland; Rats; Rats, Inbred Strains | 1990 |
Muscimol injections in the medial septum impair spatial learning.
Topics: Animals; Choline; gamma-Aminobutyric Acid; Hippocampus; Learning; Male; Microinjections; Muscimol; Neural Pathways; Rats; Rats, Inbred Strains; Reaction Time; Septal Nuclei; Spatial Behavior | 1990 |
GABAergic mechanisms in the cat red nucleus: effects of intracerebral microinjections of muscimol or bicuculline on a conditioned motor task.
Topics: Animals; Bicuculline; Cats; Conditioning, Operant; gamma-Aminobutyric Acid; Injections, Intraventricular; Microinjections; Muscimol; Psychomotor Performance; Reaction Time; Red Nucleus | 1990 |
Does GABA act through dopaminergic/cholinergic interaction in the regulation of higher environmental temperature-induced change in body temperature?
Topics: Animals; Body Temperature; Carbidopa; Choline; Cold Temperature; Dopamine; Environment; gamma-Aminobutyric Acid; Levodopa; Male; Muscimol; Neurons; Rats; Temperature | 1990 |
Myorelaxant effect of baclofen injected to the nucleus accumbens septi.
Topics: Animals; Baclofen; Behavior, Animal; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Haloperidol; Injections, Intraperitoneal; Male; Microinjections; Midazolam; Muscimol; Muscle Relaxation; Nicardipine; Nucleus Accumbens; Rats; Rats, Inbred Strains; Task Performance and Analysis | 1990 |
Bicuculline and picrotoxin block phase advances induced by GABA agonists in the circadian rhythm of locomotor activity in the golden hamster by a phaclofen-insensitive mechanism.
Topics: Animals; Baclofen; Bicuculline; Circadian Rhythm; Cricetinae; gamma-Aminobutyric Acid; Male; Mesocricetus; Microinjections; Motor Activity; Muscimol; Picrotoxin; Stereotaxic Techniques; Triazolam | 1990 |
Systemic CI-966, a new gamma-aminobutyric acid uptake blocker, enhances gamma-aminobutyric acid action in CA1 pyramidal layer in situ.
Topics: Animals; gamma-Aminobutyric Acid; Hippocampus; Iontophoresis; Male; Muscimol; Nipecotic Acids; Pharmaceutical Vehicles; Pyramidal Tracts; Pyridines; Rats; Rats, Inbred Strains | 1990 |
Changes in succinate dehydrogenase activity of rats after intraventricular injections of GABA, muscimol and picrotoxin.
Topics: Animals; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Succinate Dehydrogenase | 1990 |
Identification of GABAergic amacrine cell-like neurons developing in chick retinal monolayer cultures.
Topics: Animals; Cells, Cultured; Chick Embryo; Evoked Potentials; Fluorescent Antibody Technique; gamma-Aminobutyric Acid; Glycine; Immunoenzyme Techniques; Muscimol; Retinal Ganglion Cells | 1990 |
Effects of excitatory and inhibitory amino acid agonists and antagonists of ventral horn cells in slices of spinal cord isolated from adult rats.
Topics: Action Potentials; Amino Acids; Animals; Anterior Horn Cells; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Male; Muscimol; Rats; Rats, Inbred Strains; Strychnine; Synapses | 1990 |
Increased GABAergic transmission in medial hypothalamus facilitates lordosis but has the opposite effect in preoptic area.
Topics: Animals; Bicuculline; Female; gamma-Aminobutyric Acid; Hypothalamus, Middle; Muscimol; Posture; Preoptic Area; Rats; Rats, Inbred Strains; Sexual Behavior, Animal | 1990 |
GABA-mediated regulation of feline aggression elicited from midbrain periaqueductal gray.
Topics: Aggression; Animals; Bicuculline; Cats; Dose-Response Relationship, Drug; Electric Stimulation; Female; gamma-Aminobutyric Acid; Male; Muscimol; Periaqueductal Gray | 1990 |
Butyrylcholinesterase fluctuation in male albino rats with intracerebroventricular injection of gamma aminobutyric acid, muscimol, and picrotoxin.
Topics: Animals; Butyrylcholinesterase; Cholinesterases; gamma-Aminobutyric Acid; Hypothalamus; Injections, Intraventricular; Male; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains | 1990 |
Effects of DM-9384 in a model of amnesia based on animals with GABAergic neuronal dysfunctions.
Topics: Amnesia; Animals; Avoidance Learning; Bicuculline; Central Nervous System Agents; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred Strains; Muscimol; Nervous System Diseases; Picrotoxin; Pyrrolidinones; Synaptic Membranes | 1990 |
Central inhibition by gamma-aminobutyric acid and muscimol of the release of vasopressin and oxytocin by an osmotic stimulus in the rat.
Topics: Animals; Diuresis; Female; gamma-Aminobutyric Acid; Injections, Intraventricular; Iodine Radioisotopes; Lactation; Male; Muscimol; Osmolar Concentration; Oxytocin; Pregnancy; Rats; Rats, Inbred Strains; Vasopressins | 1990 |
Gamma-aminobutyric acid and chloride channels: regulation by neuropeptides.
Topics: Animals; Carbolines; Cells, Cultured; Cerebellum; Chlorides; gamma-Aminobutyric Acid; Hippocampus; Humans; Ion Channels; Muscimol; Nerve Tissue Proteins; Receptors, GABA-A | 1985 |
Colocalization of [3H]muscimol and antisera to GABA and glutamic acid decarboxylase within the same neurons in monkey retina.
Topics: Animals; Autoradiography; Fluorescent Antibody Technique; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Immune Sera; Immunoenzyme Techniques; Macaca fascicularis; Macaca nemestrina; Muscimol; Neurons; Retina; Staining and Labeling | 1985 |
Possible involvement of low and high affinity GABA receptors in the chloride influx into synaptosomes.
Topics: 4-Aminobutyrate Transaminase; Aldehyde Oxidoreductases; Animals; Chlorides; Diazepam; gamma-Aminobutyric Acid; Ion Channels; Muscimol; Phenobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes | 1986 |
gamma-Aminobutyric acid (GABA)- and barbiturate-mediated 36Cl- uptake in rat brain synaptoneurosomes: evidence for rapid desensitization of the GABA receptor-coupled chloride ion channel.
Topics: Animals; Cerebral Cortex; Chlorides; Dose-Response Relationship, Drug; Ethanol; gamma-Aminobutyric Acid; Ion Channels; Male; Muscimol; Pentobarbital; Ranidae; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes | 1986 |
The central pressor actions of substance P are inhibited by GABA.
Topics: Animals; Blood Pressure; Catecholamines; gamma-Aminobutyric Acid; Heart Rate; Injections, Intravenous; Male; Muscimol; Rats; Rats, Inbred Strains; Substance P | 1986 |
GABAergic modulation of a substance P-mediated reflex of slow time course in the isolated rat spinal cord.
Topics: Animals; Baclofen; Bicuculline; Diazepam; Electrophysiology; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Rats; Rats, Inbred Strains; Reflex; Spinal Cord; Substance P | 1987 |
Involvement of substance P in the excitatory action of GABAA agonists on cholinergic neurons in the guinea-pig ileum.
Topics: Animals; Capsaicin; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Muscle, Smooth; Parasympathetic Nervous System; Peptide Fragments; Substance P; Taurine | 1987 |
Gamma-aminobutyric acid modulates chloride channel activity in cultured primary bovine lactotrophs.
Topics: Animals; Bicuculline; Cattle; Cells, Cultured; Chlorides; gamma-Aminobutyric Acid; Ion Channels; Membrane Potentials; Muscimol; Pituitary Gland, Anterior; Prolactin | 1987 |
Kinetic and pharmacological properties of the GABA-induced chloride current in Aplysia neurones: a 'concentration clamp' study.
Topics: Animals; Aplysia; beta-Alanine; Chlorides; Diazepam; gamma-Aminobutyric Acid; Ion Channels; Kinetics; Muscimol; Neurons; Pentobarbital | 1988 |
Effect of gamma-aminobutyric acid (GABA) on vasodilation in resistance-sized arteries isolated from the monkey, rabbit, and rat.
Topics: Animals; Arteries; Bicuculline; Dinoprost; gamma-Aminobutyric Acid; In Vitro Techniques; Macaca fascicularis; Male; Muscimol; Muscle Relaxation; Papaverine; Potassium; Potassium Chloride; Rabbits; Rats; Rats, Inbred Strains; Vascular Resistance; Vasodilation | 1988 |
cAMP and forskolin decrease gamma-aminobutyric acid-gated chloride flux in rat brain synaptoneurosomes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Brain; Bucladesine; Chloride Channels; Chlorides; Colforsin; Cyclic AMP; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Proteins; Muscimol; Rats; Synaptosomes | 1989 |
Effect of the body temperature upon central administration of substance P--the role of adrenalectomy and GABA-activation.
Topics: Adrenalectomy; Animals; Body Temperature; gamma-Aminobutyric Acid; Hypothalamus, Anterior; Injections; Male; Muscimol; Rats; Rats, Inbred Strains; Substance P | 1988 |
Chemical kindling decreases GABA-activated chloride channels of mouse brain.
Topics: Animals; Autoradiography; Brain Chemistry; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Convulsants; gamma-Aminobutyric Acid; Ion Channels; Kindling, Neurologic; Male; Mice; Mice, Inbred ICR; Muscimol; Sulfur Radioisotopes | 1989 |
Macrolide compounds, ivermectin and milbemycin D, stimulate chloride channels sensitive to GABAergic drugs in cultured chick spinal neurons.
Topics: Animals; Anti-Bacterial Agents; Bicuculline; Cells, Cultured; Chick Embryo; Chlorides; Diazepam; gamma-Aminobutyric Acid; Ion Channels; Ivermectin; Lactones; Macrolides; Membrane Potentials; Muscimol; Neurons; Picrotoxin; Sesterterpenes; Spinal Cord | 1989 |
gamma-Aminobutyric acid-activated chloride channels: relationship to genetic differences in ethanol sensitivity.
Topics: Animals; Cerebellum; Chloride Channels; Chlorides; Ethanol; gamma-Aminobutyric Acid; Genetics; Ion Channels; Male; Membrane Proteins; Mice; Muscimol; Rats; Sleep | 1988 |
Substance P and GABAergic effects on adrenal and autonomic function evoked by microinjections into trigeminal subnucleus caudalis in the cat.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Autonomic Nervous System; Bicuculline; Blood Pressure; Catecholamines; Cats; Female; gamma-Aminobutyric Acid; Heart Rate; Male; Muscimol; Substance P; Trigeminal Nucleus, Spinal | 1989 |
Intranigral GABAergic drug effects on striatal dopamine activity.
Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Animals; Bicuculline; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Muscimol; Rats; Rats, Inbred Strains; Serotonin; Substantia Nigra | 1989 |
Genotype-dependent effects of GABAergic agents on sedative properties of ethanol.
Topics: Animals; Bicuculline; Ethanol; gamma-Aminobutyric Acid; Genetics, Behavioral; Genotype; Hypnotics and Sedatives; Male; Mice; Mice, Inbred A; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Muscimol; Pentobarbital; Picrotoxin; Species Specificity | 1989 |
GABAergic agents-induced antinociceptive effect in mice.
Topics: Analgesics; Animals; Baclofen; Bicuculline; Female; gamma-Aminobutyric Acid; Male; Mice; Morphine; Muscimol; Pain; Picrotoxin; Rats; Rats, Inbred Strains; Reaction Time; Sensory Thresholds; Valproic Acid | 1989 |
Postnatal evolution of the gamma-aminobutyric acid/benzodiazepine receptor complex in a model of inherited epilepsy: the quaking mouse.
Topics: Aging; Animals; Brain; Brain Stem; Cerebellum; Diazepam; Diencephalon; Epilepsy; Flunitrazepam; gamma-Aminobutyric Acid; Mice; Mice, Inbred C57BL; Mice, Quaking; Muscimol; Receptors, GABA-A; Telencephalon | 1989 |
Binding of [3H]-muscimol to GABAA sites in the guinea-pig urinary bladder: biochemical assay and autoradiography.
Topics: Animals; Autoradiography; Bicuculline; Binding, Competitive; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Isoxazoles; Muscimol; Receptors, GABA-A; Tritium; Urinary Bladder | 1989 |
Release-regulating autoreceptors of the GABAB-type in human cerebral cortex.
Topics: Aged; Aminooxyacetic Acid; Anticonvulsants; Baclofen; Cerebral Cortex; Female; GABA Antagonists; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Male; Middle Aged; Muscimol; Nipecotic Acids; Receptors, GABA-A; Synaptosomes | 1989 |
Distribution and pharmacological properties of the GABAA/benzodiazepine/chloride ionophore receptor complex in the brain of the fish Anguilla anguilla.
Topics: Anguilla; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Convulsants; Flunitrazepam; gamma-Aminobutyric Acid; Ionophores; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, GABA-A; Tissue Distribution | 1989 |
Activity-dependent disinhibition. III. Desensitization and GABAB receptor-mediated presynaptic inhibition in the hippocampus in vitro.
Topics: Animals; Baclofen; Cells, Cultured; gamma-Aminobutyric Acid; Hippocampus; Iontophoresis; Membrane Potentials; Muscimol; Neural Inhibition; Rats; Receptors, GABA-A | 1989 |
GABAA receptor-mediated positive inotropism in guinea-pig isolated left atria: evidence for the involvement of capsaicin-sensitive nerves.
Topics: Animals; Baclofen; Bicuculline; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Muscimol; Myocardial Contraction; Neurons; Neuropeptides; Receptors, GABA-A; Taurine | 1989 |
Enhancement of GABAergic transmission by zolpidem, an imidazopyridine with preferential affinity for type I benzodiazepine receptors.
Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Diazepam; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Male; Muscimol; Pyridines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptic Transmission; Zolpidem | 1989 |
Different gamma-aminobutyric acid receptor subtypes are involved in the regulation of opiate-dependent and independent luteinizing hormone-releasing hormone secretion.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Arginine Vasopressin; Baclofen; Bicuculline; Dinoprostone; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Male; Median Eminence; Muscimol; Naloxone; Narcotics; Oxytocin; Phentolamine; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1989 |
Evidence that clomethiazole interacts with the macromolecular GABA A-receptor complex in the central nervous system and in the anterior pituitary gland.
Topics: Animals; Central Nervous System; Chlormethiazole; Diazepam; gamma-Aminobutyric Acid; Hypothalamus; In Vitro Techniques; Indicators and Reagents; Male; Muscimol; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptic Transmission | 1989 |
Release of gamma-[3H]aminobutyric acid (GABA) from electrically stimulated rat cortical slices and its modulation by GABAB autoreceptors.
Topics: Animals; Baclofen; Cerebral Cortex; Electric Stimulation; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Tetrodotoxin | 1989 |
Chronic haloperidol administration increases GABA binding and enhances neuronal responsiveness to iontophoresed GABA in rat globus pallidus.
Topics: Action Potentials; Animals; Energy Metabolism; gamma-Aminobutyric Acid; Globus Pallidus; Glucose; Glycine; Haloperidol; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1989 |
GABAA receptors in the rat stomach may mediate mucoprotective effects.
Topics: Administration, Oral; Aminooxyacetic Acid; Animals; Anti-Ulcer Agents; Baclofen; Bicuculline; Binding, Competitive; Ethanol; gamma-Aminobutyric Acid; Gastric Mucosa; Ligands; Muscimol; Rats; Receptors, GABA-A; Stomach Ulcer; Vagotomy; Valproic Acid | 1989 |
Immobilized GABAA receptors and their ligand binding characteristics.
Topics: Animals; Cerebral Cortex; Concanavalin A; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Ligands; Muscimol; Polylysine; Rats; Receptors, GABA-A; Solubility | 1989 |
gamma-Aminobutyric acid inhibits the release of alpha-melanocyte-stimulating hormone from rat hypothalamic slices.
Topics: alpha-MSH; Aminooxyacetic Acid; Animals; Baclofen; gamma-Aminobutyric Acid; Hypothalamus; In Vitro Techniques; Male; Muscimol; Rats; Rats, Inbred Strains | 1989 |
Suppressive effects of intranigral injection of muscimol in three models of generalized non-convulsive epilepsy induced by chemical agents.
Topics: 4-Butyrolactone; Animals; Convulsants; Electroencephalography; Epilepsy; gamma-Aminobutyric Acid; Isoxazoles; Male; Muscimol; Pentylenetetrazole; Rats; Rats, Inbred Strains; Receptors, GABA-A; Substantia Nigra | 1989 |
gamma-Aminobutyric acid uptake by a bacterial system with neurotransmitter binding characteristics.
Topics: Binding, Competitive; gamma-Aminobutyric Acid; Kinetics; Muscimol; Pseudomonas fluorescens; Receptors, GABA-A | 1989 |
Central- and peripheral-type benzodiazepine receptors: similar regulation by stress and GABA receptor agonists.
Topics: Animals; Anxiety; Baclofen; Behavior, Animal; Benzodiazepinones; Binding Sites; Brain; Flunitrazepam; gamma-Aminobutyric Acid; Kidney; Male; Mice; Muscimol; Myocardium; Rats; Receptors, GABA-A; Stress, Physiological | 1989 |
The modulation by chlormethiazole of the GABAA-receptor complex in rat brain.
Topics: Animals; Baclofen; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chlormethiazole; CLC-2 Chloride Channels; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Picrotoxin; Rats; Receptors, GABA-A | 1989 |
GABAB receptors are up-regulated by chronic treatment with lithium or carbamazepine. GABA hypothesis of affective disorders?
Topics: Animals; Baclofen; Carbamazepine; Cerebral Cortex; gamma-Aminobutyric Acid; Hippocampus; Lithium; Male; Mood Disorders; Muscimol; Rats; Rats, Inbred WKY; Receptors, GABA-A; Synaptic Membranes | 1989 |
Further evidence for the GABAergic influence on memory. Interaction of GABAergic transmission with angiotensin II on memory processes.
Topics: Angiotensin II; Animals; Avoidance Learning; Bicuculline; gamma-Aminobutyric Acid; Male; Memory; Muscimol; Nipecotic Acids; Picrotoxin; Proline; Rats; Rats, Inbred Strains; Synaptic Transmission | 1989 |
Release of endogenous GABA from the substantia nigra is not controlled by GABA autoreceptors.
Topics: Animals; Anticonvulsants; Baclofen; Bicuculline; Cerebral Cortex; Electric Stimulation; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Nipecotic Acids; Potassium; Rats; Rats, Inbred Strains; Receptors, GABA-A; Substantia Nigra; Tetrodotoxin | 1989 |
Responses of gamma-aminobutyrate receptor from rat brain: similarity of different preparation methods; muscimol induced desensitization and chloride exchange.
Topics: Animals; Cerebral Cortex; Chlorides; Ficoll; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Models, Neurological; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes | 1989 |
A novel type of GABA receptor in rat spinal cord?
Topics: Animals; Baclofen; Cerebral Cortex; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, GABA-A; Spinal Cord; Synaptosomes | 1989 |
The influence of antidepressive treatment on GABA-related mechanisms in the rat hippocampus: behavioral studies.
Topics: Animals; Behavior, Animal; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; gamma-Aminobutyric Acid; Hippocampus; Male; Motor Activity; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stimulation, Chemical | 1989 |
[The electrical activity of the hippocampus in rats centrally administered GABA agonists and antagonists].
Topics: Animals; Baclofen; Bicuculline; Drug Interactions; Electrodes, Implanted; Electroencephalography; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Injections, Intraventricular; Male; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1989 |
Late inhibitory postsynaptic potentials in rat prefrontal cortex may be mediated by GABAB receptors.
Topics: Animals; Baclofen; Electric Conductivity; Electric Stimulation; Evoked Potentials; Frontal Lobe; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Isoxazoles; Male; Membrane Potentials; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Serotonin; Synapses | 1989 |
Effects of intrahypothalamic injections of GABA, muscimol, pentobarbital, and L-glutamic acid on feed intake of satiated sheep.
Topics: Animals; Feeding Behavior; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hypothalamus; Male; Muscimol; Pentobarbital; Satiation; Sheep; Time Factors | 1989 |
gamma-Aminobutyric acid (GABA)-induced currents of skate Muller (glial) cells are mediated by neuronal-like GABAA receptors.
Topics: Animals; Baclofen; Bicuculline; Cells, Cultured; Electric Conductivity; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Membrane Potentials; Muscimol; Neuroglia; Neurons; Receptors, GABA-A; Skates, Fish | 1989 |
GABA as an inhibitory neurotransmitter in human cerebral cortex.
Topics: Baclofen; Cerebral Cortex; Chlorides; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Injections; Intracellular Membranes; Muscimol; Neural Inhibition; Neurons; Neurotransmitter Agents | 1989 |
gamma-Aminobutyric-acid- and pentobarbitone-gated chloride currents in internally perfused frog sensory neurones.
Topics: Action Potentials; Amino Acids; Animals; Chlorides; Dose-Response Relationship, Drug; Drug Interactions; gamma-Aminobutyric Acid; Ganglia, Spinal; In Vitro Techniques; Ion Channels; Muscimol; Neurons, Afferent; Pentobarbital | 1985 |
Effect of GABA muscimol and picrotoxin on electrical activity of the medial preoptic area in unanesthetized rats.
Topics: Animals; Electroencephalography; Electrophysiology; gamma-Aminobutyric Acid; Male; Muscimol; Picrotoxin; Preoptic Area; Rats; Rats, Inbred Strains | 1989 |
Dolichol alters GABA uptake and high affinity binding of agonist to rat brain synaptic plasma membranes.
Topics: Animals; Brain; Dolichols; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Synaptosomes | 1989 |
Augmentation of glutamate responses by GABA in the rat's motorcortex in vivo.
Topics: Animals; Aspartic Acid; Baclofen; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Motor Cortex; Muscimol; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats | 1989 |
Conditioned place aversion produced by microinjections of semicarbazide into the periaqueductal gray of the rat.
Topics: Animals; Avoidance Learning; Conditioning, Classical; gamma-Aminobutyric Acid; Male; Muscimol; Periaqueductal Gray; Rats; Semicarbazides | 1989 |
Dorsal pallidum as a functional motor output of the corpus striatum.
Topics: Animals; Corpus Striatum; Dopamine; Efferent Pathways; gamma-Aminobutyric Acid; Globus Pallidus; Haloperidol; Male; Muscimol; Psychomotor Performance; Rats; Rats, Inbred Strains; Reaction Time | 1989 |
Eye movements induced by microinjection of GABA agonist in the rat substantia nigra pars reticulata.
Topics: Animals; Electromyography; Eye Movements; gamma-Aminobutyric Acid; Male; Microinjections; Movement; Muscimol; Neck Muscles; Rats; Rats, Inbred Strains; Saccades; Substantia Nigra | 1989 |
The role of the nigrotegmental GABAergic pathway in the propagation of pentylenetetrazol-induced seizures.
Topics: Animals; Bicuculline; gamma-Aminobutyric Acid; Male; Muscimol; Pentylenetetrazole; Pons; Rats; Rats, Inbred Strains; Seizures; Substantia Nigra; Superior Colliculi | 1989 |
Fluidization of brain membranes by A2C does not produce anesthesia and does not augment muscimol-stimulated 36Cl- influx.
Topics: Anesthesia; Animals; Benzyl Alcohols; Brain Chemistry; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Chlorine; gamma-Aminobutyric Acid; Male; Membrane Fluidity; Membranes; Mice; Mice, Inbred ICR; Muscimol; Radioisotopes; Stearates; Stearic Acids; Synaptosomes; Temperature | 1989 |
GABA- and glutamate-mediated synaptic potentials in rat dorsal raphe neurons in vitro.
Topics: Animals; Bicuculline; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; In Vitro Techniques; Membranes; Muscimol; Picrotoxin; Raphe Nuclei; Rats; Synapses | 1989 |
Modulation of sympathetic discharge by a hypothalamic GABAergic mechanism.
Topics: Animals; Blood Pressure; Cats; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; Hypothalamus; Hypothalamus, Posterior; Injections; Muscimol; Paralysis; Picrotoxin; Sympathetic Nervous System | 1989 |
Release of taurine and GABA from cerebellar slices from developing and adult mice.
Topics: Aging; Animals; Bicuculline; Cerebellum; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Male; Mice; Muscimol; Potassium; Taurine | 1989 |
Effects of naloxone and naltrexone on memory consolidation in CD1 mice: involvement of GABAergic mechanisms.
Topics: Animals; Avoidance Learning; Bicuculline; gamma-Aminobutyric Acid; Male; Memory; Mice; Mice, Inbred Strains; Muscimol; Naloxone; Naltrexone; Picrotoxin | 1989 |
Injection of benzodiazepines but not GABA or muscimol into pars reticulata substantia nigra suppresses pentylenetetrazol seizures.
Topics: Animals; Benzodiazepines; Flurazepam; gamma-Aminobutyric Acid; Male; Midazolam; Muscimol; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures; Substantia Nigra | 1989 |
GABAergic modulation of acetylcholine release in cholinergic synaptosomes from Torpedo marmorata electric organ.
Topics: Acetylcholine; Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Muscimol; Potassium; Synaptosomes; Torpedo | 1989 |
Injection of muscimol into posterior hypothalamus blocks stress-induced tachycardia.
Topics: Animals; Bicuculline; Blood Pressure; gamma-Aminobutyric Acid; Heart Rate; Hypothalamus; Hypothalamus, Posterior; Male; Muscimol; Rats; Rats, Inbred Strains; Stress, Physiological | 1989 |
Involvement of the amygdala GABAergic system in the modulation of memory storage.
Topics: Amygdala; Animals; Avoidance Learning; Bicuculline; gamma-Aminobutyric Acid; Male; Memory; Muscimol; Rats; Rats, Inbred Strains | 1989 |
gamma-Aminobutyric acid regulation of neurohypophysial hormone secretion in male and female rats.
Topics: Animals; Arginine Vasopressin; Bicuculline; Dose-Response Relationship, Drug; Female; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Oxytocin; Picrotoxin; Pituitary Gland, Posterior; Rats; Rats, Inbred Strains; Time Factors; Veratridine | 1989 |
Qualitative and quantitative changes in monoamine oxidase activity after acute third ventricle treatment of GABA, muscimol, and picrotoxin in rat.
Topics: Animals; Brain; Cytophotometry; gamma-Aminobutyric Acid; Histocytochemistry; Injections, Intraventricular; Male; Monoamine Oxidase; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains | 1989 |
Effect of NC-1100 [1-(3,4-dimethoxyphenyl)-2-(4-diphenylmethylpiperazinyl) ethanol dihydrochloride] on gamma-aminobutyric acid (GABA) metabolism in rat brain: analysis using stroke-prone spontaneously hypertensive rat.
Topics: 4-Aminobutyrate Transaminase; Amino Acids; Animals; Brain; Cerebrovascular Disorders; gamma-Aminobutyric Acid; Glutamate Decarboxylase; In Vitro Techniques; Male; Muscimol; Nerve Tissue Proteins; Piperazines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Synapses; Vasodilator Agents | 1989 |
Effect of GABA (gamma-aminobutyric acid) on neurotransmission in inferior colliculus slices from the guinea pig.
Topics: Action Potentials; Animals; Baclofen; Bicuculline; Chlorides; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Inferior Colliculi; Muscimol; Neural Inhibition | 1989 |
Blockade of enkephalinergic and GABAergic mediated locomotion in the nucleus accumbens by muscimol in the ventral pallidum.
Topics: Animals; Carbachol; Dopamine; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; gamma-Aminobutyric Acid; Globus Pallidus; Injections; Male; Motor Activity; Muscimol; Nucleus Accumbens; Picrotoxin; Rats; Rats, Inbred Strains; Septal Nuclei | 1989 |
Effects of muscimol, cetyl-GABA, pentetrazol and picrotoxin on timidity during intraspecies conflict in mice.
Topics: Aggression; Animals; GABA Antagonists; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Pentylenetetrazole; Picrotoxin; Species Specificity | 1989 |
Pharmacology of a novel effect of gamma-aminobutyric acid on the frog optic tectum in vitro.
Topics: Animals; Bicuculline; Chlorides; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Midazolam; Muscimol; Pentobarbital; Rana temporaria; Superior Colliculi | 1989 |
Biochemical evidence for the GABA regulation of vasopressin levels in microdissected brain structures after servo-controlled hypotension.
Topics: 3-Mercaptopropionic Acid; Animals; Brain; Enzyme Inhibitors; gamma-Aminobutyric Acid; Hypotension; Male; Muscimol; Rats; Rats, Inbred Lew; Sulfhydryl Compounds; Vasopressins | 1989 |
Effects of GABA-ergic agents on spontaneous non-convulsive epilepsy, EEG and behaviour, in the WAG/RIJ inbred strain of rats.
Topics: Animals; Behavior, Animal; Bicuculline; Electroencephalography; Epilepsy; Female; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Muscimol; Rats; Rats, Inbred Strains | 1989 |
Baclofen and phaclofen modulate GABA release from slices of rat cerebral cortex and spinal cord but not from retina.
Topics: Amino Acids; Aminocaproates; Aminolevulinic Acid; Animals; Baclofen; Calcium; Cerebral Cortex; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Potassium; Rats; Rats, Inbred Strains; Retina; Spinal Cord; Vigabatrin | 1989 |
Centrally administered GABA and GABA-selective agonist and antagonist in rats: histoenzymological cytophotometric study.
Topics: Acetylcholinesterase; Animals; Butyrylcholinesterase; Cytophotometry; gamma-Aminobutyric Acid; Histocytochemistry; Hypothalamus; Injections, Intraventricular; Male; Monoamine Oxidase; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Succinate Dehydrogenase | 1989 |
[3H]muscimol labels neurons in both the superficial and deep layers of cat superior colliculus.
Topics: Animals; Autoradiography; Cats; gamma-Aminobutyric Acid; Microscopy, Electron; Muscimol; Neurons; Superior Colliculi | 1989 |
GABA binding to receptor sites in locust supraoesophageal ganglia.
Topics: Animals; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia; Grasshoppers; Hydrogen-Ion Concentration; Kinetics; Muscimol; Neurons; Receptors, GABA-A | 1987 |
Modulation of calcium uptake and D-aspartate release by GABAB receptors in cultured cerebellar granule cells.
Topics: Animals; Aspartic Acid; Baclofen; Calcimycin; Calcium; Calcium Radioisotopes; Cells, Cultured; Cerebellum; gamma-Aminobutyric Acid; Muscimol; Nimodipine; Rats; Receptors, GABA-A | 1987 |
Characteristics of flunitrazepam binding to intact primary cultured spinal cord neurons and its modulation by GABAergic drugs.
Topics: Animals; Benzodiazepines; Binding, Competitive; Carbolines; Cells, Cultured; Embryo, Mammalian; Etazolate; Etomidate; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Mice; Mice, Inbred C57BL; Muscimol; Neurons; Pentobarbital; Receptors, GABA-A; Spinal Cord | 1987 |
Further evidence for abnormal GABAergic circuits in amygdala-kindled rats.
Topics: Amygdala; Animals; Brain; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Kindling, Neurologic; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes | 1987 |
Behavioral measurement of benzodiazepine tolerance and GABAergic subsensitivity in the substantia nigra pars reticulata.
Topics: Administration, Oral; Animals; Dose-Response Relationship, Drug; Drug Tolerance; Flurazepam; gamma-Aminobutyric Acid; Male; Microinjections; Muscimol; Rats; Receptors, GABA-A; Stereotyped Behavior; Substantia Nigra; Time Factors | 1988 |
Heterogeneity of gamma-aminobutyric acid/benzodiazepine/beta-carboline receptor complex in rat spinal cord.
Topics: Animals; Bicuculline; Binding, Competitive; Carbolines; Cerebellum; Diazepam; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Receptors, GABA-A; Spinal Cord; Synaptic Membranes | 1988 |
Melatonin enhancement of [3H]-gamma-aminobutyric acid and [3H]muscimol binding in rat brain.
Topics: Animals; Brain; Diazepam; Dose-Response Relationship, Drug; Freezing; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Melatonin; Muscimol; Octoxynol; Polyethylene Glycols; Rats; Rats, Inbred Strains; Receptors, GABA-A; Tritium | 1988 |
Effects of ethanol on passive avoidance behavior in the mouse: involvement of GABAergic mechanisms.
Topics: Animals; Avoidance Learning; Bicuculline; Ethanol; gamma-Aminobutyric Acid; Male; Memory; Mice; Muscimol; Picrotoxin; Receptors, GABA-A | 1988 |
Inhibitory effects of quinolone antibacterial agents on gamma-aminobutyric acid binding to receptor sites in rat brain membranes.
Topics: Animals; Anti-Infective Agents; Brain; Cell Membrane; Chemical Phenomena; Chemistry; gamma-Aminobutyric Acid; Muscimol; Quinolines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synapses | 1988 |
Oral movements induced by interference with nigral GABA neurotransmission: relationship to tardive dyskinesias.
Topics: Animals; Bicuculline; Dyskinesia, Drug-Induced; GABA Antagonists; gamma-Aminobutyric Acid; Injections; Isoniazid; Mastication; Mouth; Movement; Muscimol; Substantia Nigra; Synaptic Transmission; Tectum Mesencephali; Tegmentum Mesencephali | 1988 |
GABAA receptor populations bind agonists and antagonists differentially and with opposite affinities.
Topics: Affinity Labels; Androstanes; Animals; Azasteroids; Brain; Diazepam; Diazonium Compounds; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Photochemistry; Pyridazines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sulfanilic Acids; Synaptic Membranes | 1988 |
Independent GABAergic and cholinergic modulation of apomorphine-induced stereotyped rearing in the rat.
Topics: Animals; Apomorphine; Atropine; Bicuculline; Carbachol; Caudate Nucleus; Female; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Receptors, GABA-A; Stereotyped Behavior | 1988 |
Sensitivity of embryonic spontaneous motility to the GABA agonists baclofen and muscimol.
Topics: Animals; Baclofen; Chick Embryo; gamma-Aminobutyric Acid; Motor Activity; Muscimol; Receptors, GABA-A; Time Factors | 1988 |
Unilateral eyelid suture increases GABAA receptors in cat visual cortex.
Topics: Age Factors; Animals; Cats; Functional Laterality; gamma-Aminobutyric Acid; Kinetics; Muscimol; Receptors, GABA-A; Visual Cortex; Visual Pathways | 1988 |
Bicuculline up-regulation of GABAA receptors in rat brain.
Topics: Animals; Bicuculline; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebellum; Corpus Striatum; Flunitrazepam; Frontal Lobe; gamma-Aminobutyric Acid; Male; Muscimol; Octoxynol; Polyethylene Glycols; Rats; Rats, Inbred Strains; Receptors, GABA-A; Substantia Nigra; Synaptic Membranes | 1988 |
Chronic ethanol administration alters gamma-aminobutyric acid, pentobarbital and ethanol-mediated 36Cl- uptake in cerebral cortical synaptoneurosomes.
Topics: Administration, Inhalation; Animals; Cerebral Cortex; Chlorides; Dose-Response Relationship, Drug; Ethanol; gamma-Aminobutyric Acid; Male; Muscimol; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synapses | 1988 |
Potential involvement of a baclofen-sensitive autoreceptor in the modulation of the release of endogenous GABA from rat brain slices in vitro.
Topics: Animals; Baclofen; Bicuculline; Brain; Cerebral Cortex; Corpus Striatum; Electric Stimulation; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Substantia Nigra | 1988 |
Presynaptic modulation of the release of GABA by GABAA receptors in pars compacta and by GABAB receptors in pars reticulata of the rat substantia nigra.
Topics: Animals; Baclofen; Bicuculline; Brain; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Potassium; Rats; Rats, Inbred Strains; Receptors, GABA-A; Substantia Nigra | 1988 |
GABAB receptor-mediated inhibition of histamine H1-receptor-induced inositol phosphate formation in slices of rat cerebral cortex.
Topics: Animals; Baclofen; Carbachol; Cerebral Cortex; gamma-Aminobutyric Acid; Histamine; Inositol; Inositol Phosphates; Isonicotinic Acids; Kinetics; Lithium; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Histamine H1; Sugar Phosphates | 1988 |
GABAA and GABAB sites in bovine adrenal medulla membranes.
Topics: Adrenal Medulla; Animals; Baclofen; Binding Sites; Calcium; Cattle; Cell Membrane; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Muscimol; Receptors, GABA-A | 1988 |
Exacerbation of indomethacin-induced gastric ulceration by systemically administered GABA in rats: possible involvement of peripheral GABA receptors.
Topics: Animals; Anticonvulsants; Atropine; beta-Alanine; Bicuculline; Drug Synergism; gamma-Aminobutyric Acid; Glycine; Indomethacin; Male; Muscimol; Pentobarbital; Pentylenetetrazole; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stomach Ulcer; Taurine | 1988 |
Cerebellar GABAA and benzodiazepine receptor characteristics in young and aged mice.
Topics: Aging; Animals; Cerebellum; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred ICR; Muscimol; Receptors, GABA-A | 1988 |
Delta-guanidinovaleric acid as an endogenous and specific GABA-receptor antagonist: electroencephalographic study.
Topics: Animals; Arginine; Cerebral Cortex; Diazepam; Electroencephalography; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures; Valerates | 1987 |
5-Hydroxytryptamine facilitates GABA-induced depolarization in bullfrog primary afferent neurons.
Topics: Animals; gamma-Aminobutyric Acid; Ganglia, Spinal; In Vitro Techniques; Membrane Potentials; Muscimol; Neurons, Afferent; Rana catesbeiana; Receptors, GABA-A; Serotonin | 1988 |
Release-regulating GABAA receptors are present on noradrenergic nerve terminals in selective areas of the rat brain.
Topics: Animals; Baclofen; Brain; Cerebral Cortex; gamma-Aminobutyric Acid; Hippocampus; Hypothalamus; Male; Muscimol; Nerve Endings; Norepinephrine; Organ Specificity; Rats; Rats, Inbred Strains; Receptors, GABA-A; Reference Values; Synaptosomes | 1987 |
GABAA-receptor-mediated inhibition of the delayed increase in intragastric pressure to stimulation of vagal afferent fibres in cats.
Topics: Animals; Baclofen; Cats; Electric Stimulation; Female; gamma-Aminobutyric Acid; Hexamethonium Compounds; Male; Muscimol; Muscle Contraction; Neurons, Afferent; Pressure; Receptors, GABA-A; Stomach; Vagus Nerve | 1988 |
GABA-ergic mechanisms in the anticonvulsive activity of newly synthesized barbiturates. II. Correlation of HB-7 with GABA-ergic agents.
Topics: Animals; Anticonvulsants; Baclofen; Barbiturates; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Mice; Muscimol; Pentobarbital; Receptors, GABA-A | 1988 |
Classification of GABA receptors in snail neurones.
Topics: Animals; Baclofen; gamma-Aminobutyric Acid; Membrane Potentials; Muscimol; Neurons; Receptors, GABA-A; Snails | 1988 |
Valproate enhances GABA-A mediated inhibition of locus coeruleus neurones in vitro.
Topics: Animals; gamma-Aminobutyric Acid; In Vitro Techniques; Locus Coeruleus; Male; Muscimol; Neurons; Rats; Rats, Inbred Strains; Receptors, GABA-A; Valproic Acid | 1988 |
Drugs which stimulate or facilitate central GABAergic transmission interact synergistically with delta-9-tetrahydrocannabinol to produce marked catalepsy in mice.
Topics: Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Catalepsy; Dronabinol; Drug Synergism; Flumazenil; Flupenthixol; Flurazepam; GABA Antagonists; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Nipecotic Acids; Receptors, GABA-A; Strychnine; Taurine; Tiagabine | 1988 |
Excitatory and inhibitory action of GABA on synaptic transmission in slices of guinea pig superior colliculus.
Topics: Animals; Baclofen; Bicuculline; Dose-Response Relationship, Drug; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Muscimol; Nipecotic Acids; Perfusion; Proline; Receptors, GABA-A; Superior Colliculi; Synaptic Membranes; Synaptic Transmission | 1988 |
Quantitative studies on some antagonists of N-methyl D-aspartate in slices of rat cerebral cortex.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Corpus Callosum; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Ketamine; Male; Muscimol; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons; Oxadiazoles; Potassium; Quisqualic Acid; Rats; Rats, Inbred Strains; Tetrodotoxin | 1985 |
gamma-Aminobutyric acid: temperature dependence in benzodiazepine receptor binding.
Topics: Animals; Anti-Anxiety Agents; Cell Membrane; Diencephalon; Flunitrazepam; gamma-Aminobutyric Acid; Mice; Muscimol; Receptors, GABA-A; Telencephalon; Temperature | 1985 |
The modulation of cortical acetylcholine release by GABA, GABA-like drugs and benzodiazepines in freely moving guinea-pigs.
Topics: Acetylcholine; Aminobutyrates; Animals; Anti-Anxiety Agents; Benzodiazepines; Cerebral Cortex; Ethanolamines; Female; gamma-Aminobutyric Acid; Guinea Pigs; Isoxazoles; Male; Muscimol; Serotonin Antagonists | 1985 |
Somatostatin secretion from the hypothalamus.
Topics: Animals; Carbachol; Cells, Cultured; Cerebral Cortex; gamma-Aminobutyric Acid; Hypothalamus; Immunologic Techniques; Membrane Potentials; Muscimol; Norepinephrine; Picrotoxin; Potassium; Rats; Secretory Rate; Sesterterpenes; Somatostatin; Tetradecanoylphorbol Acetate | 1985 |
Pharmacological properties of gamma-aminobutyric acid-, glutamate-, and aspartate-induced depolarizations in cultured astrocytes.
Topics: Animals; Aspartic Acid; Astrocytes; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Muscimol; Rats | 1985 |
Decreased neurotransmitter receptor binding in striatum and cortex from adult hypothyroid rats.
Topics: Animals; Choline O-Acetyltransferase; Corpus Striatum; Dioxanes; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hypothyroidism; Muscimol; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Spiperone; Tyrosine 3-Monooxygenase; Visual Cortex | 1986 |
Involvement of noradrenaline in potentiation of the head-twitch response by GABA-related drugs.
Topics: Adrenergic beta-Antagonists; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Brain Chemistry; Catecholamines; Diazepam; Dopamine; Drug Synergism; gamma-Aminobutyric Acid; Male; Methoxydimethyltryptamines; Metoprolol; Mice; Muscimol; Norepinephrine; Pentobarbital; Picrotoxin; Stereotyped Behavior; Taurine | 1986 |
Control of rat gastric somatostatin release by gamma-aminobutyric acid (GABA).
Topics: Animals; Atropine; gamma-Aminobutyric Acid; Gastric Mucosa; Gastrins; In Vitro Techniques; Male; Muscimol; Radioimmunoassay; Rats; Rats, Inbred Strains; Somatostatin; Time Factors | 1986 |
The rat ventromedial thalamic nucleus and motor control: role of N-methyl-D-aspartate-mediated excitation, GABAergic inhibition, and muscarinic transmission.
Topics: Animals; Aspartic Acid; Electromyography; gamma-Aminobutyric Acid; Locomotion; Male; Movement; Muscimol; Muscle Contraction; N-Methylaspartate; Neuromuscular Junction; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Synaptic Transmission; Thalamic Nuclei | 1986 |
Deep prepyriform cortex kindling and its relation to amygdala kindling in the rat.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amygdala; Animals; Aspartic Acid; Cerebral Cortex; Electroencephalography; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Muscimol; N-Methylaspartate; Rats; Valine | 1986 |
Kindling-induced changes in EEG recorded during stimulation from the site of stimulation. III. Direct pharmacological manipulations of the kindled amygdala.
Topics: 2-Amino-5-phosphonovalerate; Amygdala; Animals; Atropine; Baclofen; Diazepam; Electroencephalography; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Muscimol; Neural Inhibition; Rats; Rats, Inbred Strains; Reaction Time; Receptors, GABA-A; Valine | 1987 |
Development of gamma-aminobutyric acid (GABA)ergic neurons in cerebral cortical neurons in primary culture.
Topics: 4-Aminobutyrate Transaminase; Animals; Cell Differentiation; Cells, Cultured; Cerebral Cortex; Flunitrazepam; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamates; Glutamic Acid; Histocytochemistry; Immunoenzyme Techniques; Mice; Microscopy, Electron, Scanning; Muscimol; Receptors, GABA-A; Time Factors | 1987 |
Differential mechanisms involved in the anticonflict action of benzodiazepines injected into the central amygdala and mammillary body.
Topics: Amygdala; Animals; Anti-Anxiety Agents; Atropine; Conflict, Psychological; Diazepam; gamma-Aminobutyric Acid; Male; Mammillary Bodies; Microinjections; Muscimol; Punishment; Rats; Rats, Inbred Strains | 1987 |
gamma-Aminobutyric acid-induced modulation of acetylcholine release from the guinea pig lung.
Topics: Acetylcholine; Animals; Baclofen; Bicuculline; Calcium; Dose-Response Relationship, Drug; Female; Furosemide; gamma-Aminobutyric Acid; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Lung; Male; Muscimol; Tetrodotoxin | 1987 |
GABA binding in bovine adrenal medulla membranes is sensitive to baclofen.
Topics: Adrenal Medulla; Animals; Baclofen; Bicuculline; Cattle; Cell Membrane; gamma-Aminobutyric Acid; Kinetics; Muscimol; Receptors, GABA-A | 1987 |
Amino acid influences on seizures elicited within the inferior colliculus.
Topics: Amino Acids; Aminobutyrates; Animals; Aspartic Acid; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Inferior Colliculi; Male; Muscimol; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Taurine | 1987 |
Dopaminergic and indoleamine-accumulating amacrine cells express GABA-like immunoreactivity in the cat retina.
Topics: Animals; Autoradiography; Cats; Dopamine; gamma-Aminobutyric Acid; Immunohistochemistry; Indoles; Muscimol; Neurons; Rabbits; Retina; Serotonin; Tyrosine 3-Monooxygenase | 1988 |
Foot-shock stress and anxiogenic beta-carbolines increase t-[35S]butylbicyclophosphorothionate binding in the rat cerebral cortex, an effect opposite to anxiolytics and gamma-aminobutyric acid mimetics.
Topics: Animals; Anti-Anxiety Agents; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Carbolines; Cell Membrane; Cerebral Cortex; Convulsants; Diazepam; Electroshock; GABA Antagonists; gamma-Aminobutyric Acid; Kinetics; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stress, Physiological | 1988 |
Regulation of [3H]GABA release from strips of guinea pig urinary bladder.
Topics: Acetylcholine; Animals; Atropine; Baclofen; Bicuculline; Clonazepam; Clonidine; Female; gamma-Aminobutyric Acid; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Male; Muscimol; Pentobarbital; Phenylephrine; Pirenzepine; Potassium; Prazosin; Tritium; Urinary Bladder; Yohimbine | 1988 |
Putative neurotransmitters involved in medullary cardiovascular regulation.
Topics: Animals; Bicuculline; Blood Pressure; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Heart Rate; Kynurenic Acid; Male; Medulla Oblongata; Microinjections; Muscimol; Neurotransmitter Agents; Rats; Rats, Inbred Strains | 1988 |
Effect of GABAergic transmission in the subpallidal region on the hypermotility response to the administration of excitatory amino acids and picrotoxin into the nucleus accumbens.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamine; Animals; Aspartic Acid; Basal Ganglia; Brain; gamma-Aminobutyric Acid; Ibotenic Acid; Kainic Acid; Male; Motor Activity; Muscimol; N-Methylaspartate; Nucleus Accumbens; Picrotoxin; Rats; Rats, Inbred Strains; Septal Nuclei; Substantia Innominata; Synaptic Transmission | 1988 |
GABA-like immunoreactivity in the cat retina: light microscopy.
Topics: Animals; Cats; Cell Count; gamma-Aminobutyric Acid; Immunohistochemistry; Muscimol; Retina | 1989 |
gamma-Aminobutyric acid inhibits beta-endorphin secretion from the anterior pituitary but not the neurointermediate lobe in the rat.
Topics: Animals; beta-Endorphin; Bicuculline; Endorphins; gamma-Aminobutyric Acid; Male; Muscimol; Pituitary Gland, Anterior; Pituitary Gland, Posterior; Rats; Rats, Inbred Strains; Stress, Physiological | 1986 |
Cholinergic and GABAergic regulation of dopamine beta-hydroxylase activity in the adrenal gland of the rat.
Topics: 5,7-Dihydroxytryptamine; Acetylcholine; Adrenal Glands; Aminocaproates; Animals; Baclofen; Bicuculline; Dopamine beta-Hydroxylase; Enzyme Induction; Fenclonine; gamma-Aminobutyric Acid; Hydroxydopamines; Male; Muscimol; Oxotremorine; Propranolol; Rats; Vigabatrin | 1986 |
[Persistence of the acquisition of an endocrine response to conditioned stress in the thalamic pigeon by chronic GABAergic treatment].
Topics: Animals; Columbidae; Conditioning, Psychological; Corticosterone; Electroshock; gamma-Aminobutyric Acid; Muscimol; Stereotaxic Techniques; Stress, Physiological; Thalamus; Time Factors | 1986 |
Modulation of acetylcholine release from rat striatal slices by the GABA/benzodiazepine receptor complex.
Topics: Acetylcholine; Animals; Atropine; Baclofen; Benzodiazepinones; Clonazepam; Corpus Striatum; Electric Stimulation; Flumazenil; gamma-Aminobutyric Acid; Haloperidol; In Vitro Techniques; Isoxazoles; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1985 |
Role of the cat substantia nigra pars reticulata in eye and head movements. II. Effects of local pharmacological injections.
Topics: Animals; Bicuculline; Cats; Eye Movements; gamma-Aminobutyric Acid; Movement; Muscimol; Orientation; Picrotoxin; Reflex; Substantia Nigra; Synaptic Transmission | 1985 |
Avermectin B1a modulation of gamma-aminobutyric acid/benzodiazepine receptor binding in mammalian brain.
Topics: Animals; Bicuculline; Brain; Cattle; Cell Membrane; Cerebral Cortex; Etazolate; gamma-Aminobutyric Acid; Isonicotinic Acids; Ivermectin; Lactones; Muscimol; Pentobarbital; Rats; Receptors, GABA-A | 1985 |
Modulation of [3H]diazepam binding in rat cortical membranes by GABAA agonists.
Topics: Androstanes; Animals; Azasteroids; Bicuculline; Cell Membrane; Cerebral Cortex; Diazepam; GABA Antagonists; gamma-Aminobutyric Acid; Imidazoles; Isonicotinic Acids; Isoxazoles; Muscimol; Piperidines; Rats; Receptors, GABA-A; Taurine | 1985 |
Modification of saccadic eye movements by GABA-related substances. I. Effect of muscimol and bicuculline in monkey superior colliculus.
Topics: Animals; Bicuculline; Eye Movements; gamma-Aminobutyric Acid; Macaca mulatta; Muscimol; Oxazoles; Saccades; Superior Colliculi; Synaptic Transmission; Visual Fields | 1985 |
Modification of saccadic eye movements by GABA-related substances. II. Effects of muscimol in monkey substantia nigra pars reticulata.
Topics: Animals; Brain Mapping; Eye Movements; gamma-Aminobutyric Acid; Macaca mulatta; Muscimol; Neural Pathways; Oxazoles; Saccades; Substantia Nigra; Superior Colliculi; Synaptic Transmission | 1985 |
Effect of GABA agonists on the neurotoxicity and anticonvulsant activity of benzodiazepines.
Topics: Animals; Anticonvulsants; Benzodiazepines; Drug Synergism; Electroshock; Flunitrazepam; gamma-Aminobutyric Acid; Isoxazoles; Male; Mice; Muscimol; Nervous System; Receptors, GABA-A | 1985 |
GABAA and GABAB receptors in detrusor strips from guinea-pig bladder dome.
Topics: Animals; Baclofen; Electric Stimulation; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Muscle, Smooth; Picrotoxin; Receptors, GABA-A; Taurine; Tetrodotoxin; Urinary Bladder | 1985 |
Autoreceptors regulate gamma-[3H]aminobutyric acid release from the guinea pig small intestine.
Topics: Animals; Baclofen; Bicuculline; Female; Furosemide; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; Male; Muscimol; Myenteric Plexus; Potassium; Receptors, GABA-A; Tetrodotoxin | 1985 |
Induction and reversal of dopamine dyskinesia in rat, cat, and monkey.
Topics: Animals; Apomorphine; Brain; Cats; Dextroamphetamine; Dopamine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Haplorhini; Humans; Levodopa; Motor Activity; Muscimol; Nomifensine; Piribedil; Rats; Receptors, Dopamine; Receptors, GABA-A; Stereotyped Behavior | 1985 |
Inhibitory effect of GABA on sympathetic neurotransmission in rabbit ear artery.
Topics: Amino Acids; Amino Acids, Neutral; Animals; Arteries; Baclofen; Ear, External; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Norepinephrine; Picrotoxin; Potassium; Rabbits; Sympathetic Nervous System; Synaptic Transmission; Taurine; Vasoconstriction | 1985 |
Specific [3H]gamma-aminobutyric acid binding to vestibular membranes of the chick inner ear.
Topics: Animals; Baclofen; Bicuculline; Binding, Competitive; Chickens; gamma-Aminobutyric Acid; Male; Muscimol; Receptors, GABA-A; Subcellular Fractions; Vestibule, Labyrinth | 1985 |
Suppression of amygdala-kindled seizure in cats by enhanced GABAergic transmission in the substantia innominata.
Topics: Amygdala; Animals; Basal Ganglia; Cats; Cyclohexanecarboxylic Acids; gamma-Aminobutyric Acid; Injections; Kindling, Neurologic; Muscimol; Seizures; Substantia Innominata; Synaptic Transmission | 1985 |
gamma-Aminobutyric acidA (GABAA) receptors modulate [3H]GABA release from isolated neuronal growth cones in the rat.
Topics: Animals; Animals, Newborn; Axons; Azides; Baclofen; Benzamides; Bicuculline; Brain; Dendrites; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Homeostasis; Muscimol; Potassium; Rats; Receptors, GABA-A; Stimulation, Chemical; Subcellular Fractions; Tritium | 1985 |
Evaluation of different GABA receptor agonists in the kindled amygdala seizure model in rats.
Topics: Amygdala; Animals; Female; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Isoxazoles; Kindling, Neurologic; Muscimol; Muscle Relaxation; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures | 1985 |
Dual effect of GABA on the contractile activity of the guinea-pig isolated urinary bladder.
Topics: Acetylcholine; Animals; Baclofen; Dimethylphenylpiperazinium Iodide; Drug Interactions; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscimol; Muscle Contraction; Muscle, Smooth; Picrotoxin; Receptors, GABA-A; Taurine; Tetrodotoxin; Urinary Bladder | 1985 |
Evidence for GABA tolerance in barbiturate-dependent and withdrawn mice.
Topics: Animals; Barbital; Barbiturates; Drug Tolerance; Female; gamma-Aminobutyric Acid; Humans; Imidazoles; Male; Mice; Muscimol; Receptors, GABA-A; Substance Withdrawal Syndrome; Substance-Related Disorders | 1985 |
An unusual effect of gamma-aminobutyric acid on synaptic transmission of frog tectal neurones in vitro.
Topics: Action Potentials; Animals; Bicuculline; Dose-Response Relationship, Drug; Evoked Potentials; gamma-Aminobutyric Acid; Hot Temperature; In Vitro Techniques; Muscimol; Neurons; Optic Nerve; Picrotoxin; Rana temporaria; Strychnine; Superior Colliculi; Synaptic Transmission | 1985 |
Electroencephalographic study of SR 95103, a GABAA antagonist: interaction with inhibitory amino acids and muscimol.
Topics: Animals; Drug Interactions; Electroencephalography; gamma-Aminobutyric Acid; Glycine; Male; Muscimol; Pyridazines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures; Taurine | 1985 |
gamma-Aminobutyric acid receptors on chick ciliary ganglion neurons in vivo and in cell culture.
Topics: Acetylcholine; Animals; Cells, Cultured; Chick Embryo; Electric Conductivity; gamma-Aminobutyric Acid; Ganglia, Parasympathetic; Muscimol; Neurons; Receptors, GABA-A | 1985 |
Disturbed GABAergic transmission in mutant Han-Wistar rats: further evidence for basal ganglia dysfunction.
Topics: Animals; Basal Ganglia Diseases; Bicuculline; Brain Chemistry; Electromyography; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Male; Muscimol; Muscles; Rats; Rats, Inbred Strains; Rats, Mutant Strains; Receptors, GABA-A; Substantia Nigra; Synaptic Transmission; Synaptosomes; Time Factors | 1985 |
Postnatal development of GABA- and glycine-mediated inhibition of feline retinal ganglion cells in the area centralis.
Topics: Animals; Bicuculline; Cats; gamma-Aminobutyric Acid; Glycine; Iontophoresis; Muscimol; Retina; Retinal Ganglion Cells; Strychnine; Synaptic Transmission | 1985 |
Effect of single or repeated estrogen administration on tuberoinfundibular GABA neurons and anterior pituitary GABA receptors: biochemical and functional studies.
Topics: Animals; Bicuculline; Binding, Competitive; Estradiol; Female; gamma-Aminobutyric Acid; Hypothalamo-Hypophyseal System; Kinetics; Muscimol; Neurons; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1985 |
Further evidence for, and nature of, the facilitatory GABAergic influence on central noradrenergic transmission.
Topics: Afferent Pathways; Animals; Central Nervous System; Cerebral Cortex; Clonidine; gamma-Aminobutyric Acid; Hypothalamus; Ibotenic Acid; Methoxyhydroxyphenylglycol; Muscimol; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, GABA-A; Serotonin; Spinal Cord; Synaptic Transmission; Yohimbine | 1985 |
Benzodiazepine binding sites in mice forebrain and kidneys: evidence for similar regulation by GABA agonists.
Topics: Animals; Brain; Flunitrazepam; gamma-Aminobutyric Acid; Kidney; Male; Mice; Muscimol; Receptors, GABA-A | 1986 |
Ontogeny of the GABA receptor complex in chick brain: studies in vivo and in vitro.
Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Chick Embryo; Flunitrazepam; gamma-Aminobutyric Acid; Muscimol; Receptors, GABA-A | 1986 |
GABAB receptors in the rabbit uterus may mediate contractile responses.
Topics: Animals; Atropine; Baclofen; Bicuculline; Dose-Response Relationship, Drug; Female; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Phentolamine; Rabbits; Receptors, GABA-A; Tetrodotoxin; Uterine Contraction | 1985 |
gamma-Aminobutyric acid, benzodiazepine binding sites and gamma-aminobutyric acid concentrations in epileptic E1 mouse brain.
Topics: Animals; Binding Sites; Brain; Epilepsy; Female; Flunitrazepam; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred Strains; Muscimol; Receptors, GABA-A | 1985 |
Regional difference in brain benzodiazepine receptor carbohydrates.
Topics: Acetylglucosaminidase; Animals; Asparagine; Benzodiazepinones; Brain Chemistry; Carbohydrates; Electrophoresis, Polyacrylamide Gel; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Male; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Molecular Weight; Muscimol; Neuraminidase; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sialic Acids; Tritium | 1986 |
A comparison of methods for removal of endogenous GABA from brain membranes prepared for binding assays.
Topics: Animals; Brain; Brain Chemistry; Cell Fractionation; Cell Membrane; Chickens; Chromatography, High Pressure Liquid; Female; gamma-Aminobutyric Acid; Kinetics; Male; Muscimol; Radioligand Assay; Receptors, GABA-A | 1986 |
Nipecotic acid, an uptake blocker, prevents fading of the gamma-aminobutyric acid effect.
Topics: Animals; Drug Synergism; gamma-Aminobutyric Acid; Hippocampus; Male; Muscimol; Nipecotic Acids; Proline; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1986 |
Involvement of the midbrain reticular formation in self-injurious behavior, stereotyped behavior, and analgesia induced by intranigral microinjection of muscimol.
Topics: Animals; Brain Mapping; gamma-Aminobutyric Acid; Male; Mesencephalon; Muscimol; Pain; Rats; Rats, Inbred Strains; Reticular Formation; Self Mutilation; Stereotyped Behavior; Substantia Nigra; Synaptic Transmission | 1986 |
Benzodiazepine- and barbiturate-interactions with GABAA receptor responses on lactotrophs.
Topics: Animals; Benzodiazepines; Clonazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Secobarbital | 1986 |
gamma-Aminobutyric acid agonists and antagonists alter chloride flux across brain membranes.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Animals; Baclofen; Bicuculline; Brain; Cell Membrane; Chlorides; gamma-Aminobutyric Acid; In Vitro Techniques; Isonicotinic Acids; Isoxazoles; Liver; Male; Mice; Mice, Inbred DBA; Muscimol; Picrotoxin; Receptors, GABA-A; Sodium; Sulfates; Taurine; Temperature | 1986 |
Effects of the potentiation of the GABAergic neurotransmission in the olfactory bulbs on mouse-killing behavior.
Topics: Aggression; Aminocaproates; Animals; Brain Chemistry; Drug Synergism; gamma-Aminobutyric Acid; Isonicotinic Acids; Isoxazoles; Male; Motor Activity; Muscimol; Nipecotic Acids; Olfactory Bulb; Proline; Rats; Rats, Inbred Strains; Synaptic Transmission; Valproic Acid; Vigabatrin | 1986 |
Genetic influences on GABA-related seizures.
Topics: 3-Mercaptopropionic Acid; Animals; Female; Flurothyl; gamma-Aminobutyric Acid; Genetics, Behavioral; Male; Mice; Mice, Inbred Strains; Muscimol; Receptors, GABA-A; Seizures; Species Specificity | 1986 |
Quantitative evaluation of the potencies of GABA-receptor agonists and antagonists using the rat hippocampal slice preparation.
Topics: Action Potentials; Animals; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Isonicotinic Acids; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1986 |
Activation of GABA receptors in the hypothalamus stimulates secretion of growth hormone and prolactin.
Topics: Animals; Anterior Hypothalamic Nucleus; Bicuculline; gamma-Aminobutyric Acid; Growth Hormone; Hypothalamus; Male; Microinjections; Muscimol; Picrotoxin; Preoptic Area; Prolactin; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1986 |
Pipecolic acid receptors in rat cerebral cortex.
Topics: Animals; Cerebral Cortex; gamma-Aminobutyric Acid; Male; Muscimol; Pipecolic Acids; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Neurotransmitter; Subcellular Fractions | 1986 |
Effects of pentylenetetrazol on GABA-A/benzodiazepine/picrotoxinin receptor complexes in rat brain regions.
Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cerebral Cortex; Corpus Striatum; Flunitrazepam; gamma-Aminobutyric Acid; Male; Muscimol; Pentylenetetrazole; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures; Tissue Distribution | 1986 |
Dopamine-GABA interactions: evidence that GABA transmits, modulates and mediates dopaminergic functions in the basal ganglia and the limbic system.
Topics: Amygdala; Animals; Basal Ganglia; Behavior, Animal; Benzodiazepines; Catalepsy; Corpus Striatum; Dopamine; Drug Interactions; Efferent Pathways; GABA Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Humans; Limbic System; Movement Disorders; Muscimol; Nucleus Accumbens; Picrotoxin; Posture; Receptors, Dopamine; Receptors, GABA-A; Substantia Nigra; Tegmentum Mesencephali; Thalamic Nuclei | 1986 |
Effects of GABA agonists on Herxheimer microshock in guinea pigs.
Topics: Anaphylaxis; Animals; Baclofen; Bronchial Spasm; gamma-Aminobutyric Acid; Guinea Pigs; Male; Muscimol; Receptors, GABA-A; Stereoisomerism | 1986 |
The colliculus superior modulates ACTH-induced excessive grooming.
Topics: Adrenocorticotropic Hormone; Animals; Behavior, Animal; Cosyntropin; GABA Antagonists; gamma-Aminobutyric Acid; Grooming; Injections, Intraventricular; Male; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Superior Colliculi | 1986 |
Modulation of the brain aversive system by GABAergic and serotonergic mechanisms.
Topics: Animals; Avoidance Learning; Benzodiazepines; Cerebral Ventricles; Chlordiazepoxide; Drug Interactions; gamma-Aminobutyric Acid; Isonicotinic Acids; Midazolam; Muscimol; Pentobarbital; Periaqueductal Gray; Rats; Receptors, GABA-A; Serotonin | 1986 |
The effects of drugs acting at the GABAA-receptor/ionophore after chemical kindling with the benzodiazepine receptor ligand FG 7142.
Topics: Animals; Bicuculline; Body Temperature; Carbolines; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Mice; Muscimol; Pentobarbital; Pentylenetetrazole; Picrotoxin; Receptors, GABA-A; Seizures; Time Factors | 1986 |
Cerebral cortical GABA and benzodiazepine binding sites in genetically seizure prone rats.
Topics: Animals; Cerebral Cortex; Dopamine; Epilepsy; Female; gamma-Aminobutyric Acid; Kinetics; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, GABA-A; Serotonin | 1986 |
The arcuate nucleus: a site for gamma-aminobutyric acid regulation of prolactin secretion.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Aspartic Acid; gamma-Aminobutyric Acid; Male; Muscimol; N-Methylaspartate; Prolactin; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1986 |
Heterogeneity of [3H]ethyl beta-carboline-3-carboxylate binding sites and [3H]gamma-aminobutyric acid binding sites.
Topics: Animals; Binding, Competitive; Carbolines; Cattle; Cerebral Cortex; Detergents; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Molecular Weight; Muscimol; Photolysis; Radioligand Assay; Receptors, GABA-A; Receptors, Neurotransmitter; Synaptosomes | 1986 |
Participation of GABA/benzodiazepine receptor system in the adrenal chromaffin cell function.
Topics: 4-Aminobutyrate Transaminase; Adrenal Medulla; Animals; Baclofen; Bicuculline; Catecholamines; Cattle; Cells, Cultured; Dogs; Enkephalin, Methionine; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Muscimol; Rats; Receptors, GABA-A; Secretory Rate | 1986 |
Estrogen-induced up-regulation of gamma-aminobutyric acid receptors in the CNS of rodents.
Topics: Animals; Brain Chemistry; Cells, Cultured; Dose-Response Relationship, Drug; Estradiol; Estrogens; Female; gamma-Aminobutyric Acid; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1986 |
Sexual dimorphism in the response of the GABAergic system to estrogen administration.
Topics: Animals; Brain; Estradiol; Estrogens; Female; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sex Characteristics | 1986 |
Nociceptive responses to altered GABAergic activity at the spinal cord.
Topics: Animals; Bicuculline; Female; gamma-Aminobutyric Acid; Injections, Spinal; Motor Activity; Muscimol; Pain; Pain Measurement; Physical Stimulation; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sensory Thresholds; Tail; Vocalization, Animal | 1986 |
The enhancement of diazepam and muscimol binding by pentobarbital and (+)-etomidate: size of the molecular arrangement estimated by electron irradiation inactivation of rat cortex.
Topics: Animals; Cerebral Cortex; Diazepam; Etomidate; gamma-Aminobutyric Acid; In Vitro Techniques; Molecular Weight; Muscimol; Pentobarbital; Rats; Receptors, GABA-A | 1986 |
Potentiation of salivary fluid secretion in ixodid ticks: a new receptor system for gamma-aminobutyric acid.
Topics: Animals; Bicuculline; Dopamine; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Picrotoxin; Receptors, GABA-A; Saliva; Spiperone; Sulpiride; Ticks | 1986 |
GABA-ergic control of alpha-melanocyte-stimulating hormone (alpha-MSH) release by frog neurointermediate lobe in vitro.
Topics: Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Immunoenzyme Techniques; Male; Melanocyte-Stimulating Hormones; Muscimol; Picrotoxin; Pituitary Gland, Anterior; Rana ridibunda; Synaptic Transmission | 1986 |
Coexistence of GABA receptors and GABA-modulin in primary cultures of rat cerebellar granule cells.
Topics: Animals; Carrier Proteins; Cells, Cultured; Cerebellum; Flunitrazepam; Fluorescent Antibody Technique; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Histocytochemistry; Membrane Proteins; Membrane Transport Proteins; Muscimol; Nerve Tissue Proteins; Organic Anion Transporters; Radioimmunoassay; Rats; Receptors, GABA-A; Synaptosomes | 1987 |
Localization of sites in periventricular forebrain mediating cardiovascular effects of gamma-aminobutyric acid agonists and antagonists in anesthetized cats.
Topics: Animals; Bicuculline; Blood Pressure; Brain Mapping; Cats; Cerebral Ventricles; gamma-Aminobutyric Acid; Heart Rate; Hemodynamics; Hypothalamus; Injections, Intraventricular; Kainic Acid; Muscimol; Receptors, GABA-A; Sympathetic Nervous System; Vagus Nerve | 1987 |
Effect of THIP and SL 76002, two clinically experimented GABA-mimetic compounds, on anterior pituitary GABA receptors and prolactin secretion in the rat.
Topics: Animals; Anticonvulsants; Bicuculline; Binding, Competitive; Female; gamma-Aminobutyric Acid; Haloperidol; Isoxazoles; Kinetics; Male; Muscimol; Ovariectomy; Oxazoles; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1987 |
Effects of chronic intracerebroventricular GABAergic treatment on basal and chronic or acute stress-induced adrenocortical activities in the thalamic pigeon.
Topics: Acute Disease; Adrenal Cortex; Animals; Chronic Disease; Columbidae; Corticosterone; Decerebrate State; gamma-Aminobutyric Acid; Muscimol; Stress, Physiological; Synaptic Transmission | 1986 |
Facilitation of premotor cortical seizure development by intranigral muscimol.
Topics: Animals; Dopamine; Epilepsies, Partial; gamma-Aminobutyric Acid; Male; Microinjections; Motor Cortex; Muscimol; Rats; Rats, Inbred Strains; Substantia Nigra; Synaptic Transmission; Thalamic Nuclei | 1987 |
Effects of GABAergic drugs on the GABA turnover in the substantia nigra and the corpus striatum of the rat.
Topics: Alkynes; Aminocaproates; Animals; Baclofen; Bicuculline; Corpus Striatum; gamma-Aminobutyric Acid; Isoxazoles; Male; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Substantia Nigra | 1987 |
Cardiorespiratory effects produced by injecting drugs that affect GABA receptors into nuclei associated with the ventral surface of the medulla.
Topics: Animals; Bicuculline; Brain Mapping; Cardiovascular Physiological Phenomena; Cats; Female; gamma-Aminobutyric Acid; Isoxazoles; Male; Medulla Oblongata; Muscimol; Respiration; Synaptic Transmission | 1987 |
Adaptation of the GABAA-receptor complex in rat brain during chronic elevation of GABA by ethanolamine O-sulphate.
Topics: 4-Aminobutyrate Transaminase; Animals; Brain Chemistry; Ethanolamines; Flurazepam; gamma-Aminobutyric Acid; Muscimol; Nipecotic Acids; Pentobarbital; Picrotoxin; Potassium; Proline; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1987 |
GABA-receptor stimulation enhances norepinephrine-induced polyphosphoinositide metabolism in rat hippocampal slices.
Topics: Animals; Bicuculline; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Inositol Phosphates; Male; Muscimol; Norepinephrine; Phosphatidic Acids; Phosphatidylinositol Phosphates; Phosphatidylinositols; Rats; Rats, Inbred Strains; Receptors, GABA-A; Taurine | 1987 |
Phospholipase C activation induced by noradrenaline in rat hippocampal slices is potentiated by GABA-receptor stimulation.
Topics: Animals; Enzyme Activation; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Kinetics; Male; Muscimol; Norepinephrine; Phosphatidylinositols; Rats; Rats, Inbred Strains; Receptors, GABA-A; Type C Phospholipases | 1987 |
Axonal GABA receptors are selectively present on normal and regenerated sensory fibers in rat peripheral nerve.
Topics: Animals; Baclofen; gamma-Aminobutyric Acid; Muscimol; Nerve Regeneration; Neurons, Afferent; Peripheral Nerves; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sciatic Nerve; Spinal Nerve Roots | 1987 |
GABA-mediated synaptic inhibition of projection neurons in the antennal lobes of the sphinx moth, Manduca sexta.
Topics: Animals; Central Nervous System; gamma-Aminobutyric Acid; Lepidoptera; Moths; Muscimol; Neural Conduction; Neural Inhibition; Neurons; Olfactory Pathways; Synapses; Synaptic Transmission | 1987 |
gamma-Aminobutyric acid receptor binding in fresh mouse brain membranes at 22 degrees C: ligand-induced changes in affinity.
Topics: Allosteric Regulation; Animals; Brain; Cell Membrane; gamma-Aminobutyric Acid; Kinetics; Ligands; Mice; Microsomes; Mitochondria; Muscimol; Pentobarbital; Receptors, GABA-A; Temperature | 1987 |
Progress towards the understanding of the GABAA receptor structure.
Topics: Allosteric Site; Animals; Benzodiazepines; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Cholic Acids; Deoxycholic Acid; Flunitrazepam; gamma-Aminobutyric Acid; Muscimol; Protein Binding; Receptors, GABA-A | 1987 |
GABA and behavioral inhibition in the neonatal rat pup.
Topics: Animals; Animals, Newborn; Behavior, Animal; gamma-Aminobutyric Acid; Muscimol; Picrotoxin; Rats | 1986 |
The relationship between hindlimb disturbances, forelimb disturbances and catalepsy after increasing doses of muscimol injected into the striatal-pallidal complex.
Topics: Animals; Bicuculline; Catalepsy; Corpus Striatum; Forelimb; gamma-Aminobutyric Acid; Globus Pallidus; Hindlimb; Injections; Male; Muscimol; Rats; Rats, Inbred Strains | 1987 |
Ontogeny of GABA-ergic and dopaminergic mediation of gnawing behavior in the mouse.
Topics: Aging; Animals; Dopamine; Female; gamma-Aminobutyric Acid; Male; Methylphenidate; Mice; Muscimol; Stereotyped Behavior | 1987 |
Evidence for a dual effect of gamma-aminobutyric acid on thyrotropin (TSH)-releasing hormone-induced TSH release from perifused rat pituitaries.
Topics: Animals; Bicuculline; Dose-Response Relationship, Drug; Drug Synergism; gamma-Aminobutyric Acid; In Vitro Techniques; Isonicotinic Acids; Male; Muscimol; Perfusion; Picrotoxin; Pituitary Gland; Pyridazines; Rats; Rats, Inbred Strains; Thyrotropin; Thyrotropin-Releasing Hormone | 1987 |
GABA suppresses stimulation-induced release of [3H]-noradrenaline from sympathetic nerve fibres in bovine ovarian follicles.
Topics: Animals; Baclofen; Bicuculline; Cattle; Desipramine; Electric Stimulation; Female; gamma-Aminobutyric Acid; Hydroxydopamines; In Vitro Techniques; Muscimol; Norepinephrine; Normetanephrine; Ovarian Follicle; Oxidopamine; Potassium Chloride; Sympathectomy, Chemical; Sympathetic Nervous System | 1987 |
Microinjection of GABA antagonists into the posterior hypothalamus elicits locomotor activity and a cardiorespiratory activation.
Topics: Animals; Bicuculline; Blood Pressure; Carbon Dioxide; Cats; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; Hypothalamus; Hypothalamus, Posterior; Microinjections; Muscimol; Picrotoxin; Respiration; Tidal Volume | 1988 |
Comparison of the biological activity of sodium valproate and L-lysine valproate on brain GABA levels by (3H) muscimol radioreceptor assay.
Topics: Animals; Brain Chemistry; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Lysine; Male; Mice; Muscimol; Radioligand Assay; Rats; Rats, Inbred Strains; Valproic Acid | 1988 |
Comparison between pentobarbital- and muscimol-induced feeding in satiated sheep.
Topics: Aminocaproates; Animals; Calcium; Eating; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Muscimol; Pentobarbital; Picrotoxin; Sheep; Sodium; Vigabatrin | 1988 |
Enhanced pressor response to GABA in the nucleus tractus solitarii of the spontaneously hypertensive rat.
Topics: Animals; Baclofen; Blood Pressure; Brain Stem; gamma-Aminobutyric Acid; Heart Rate; Hypertension; Male; Muscimol; Nipecotic Acids; Proline; Rats; Rats, Inbred SHR; Rats, Inbred Strains | 1988 |
Microinjections of GABA agonists into the amygdala complex attenuates kindled seizure expression in the rat.
Topics: Aminocaproates; Amygdala; Animals; Behavior, Animal; Cerebral Cortex; gamma-Aminobutyric Acid; Kindling, Neurologic; Limbic System; Male; Microinjections; Muscimol; Rats; Rats, Inbred Strains; Seizures; Vigabatrin | 1988 |
Evidence for the independent role of GABA synapses of the zona incerta-lateral hypothalamic region in haloperidol-induced catalepsy.
Topics: Animals; Bicuculline; Catalepsy; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Haloperidol; Hypothalamic Area, Lateral; Male; Motor Activity; Muscimol; Rats; Rats, Inbred Strains; Synapses | 1988 |
Amygdaloid kindling with bicuculline methiodide in rats.
Topics: Amygdala; Animals; Baclofen; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains | 1988 |
GABA inhibits sexual behaviour in female rats.
Topics: Aminocaproates; Animals; Bicuculline; Brain; Ejaculation; Female; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Muscimol; Rats; Rats, Inbred Strains; Sexual Behavior, Animal; Time Factors; Vigabatrin | 1988 |
Colocalization of [3H]muscimol uptake and choline acetyltransferase immunoreactivity in amacrine cells of the cat retina.
Topics: Animals; Autoradiography; Cats; Choline O-Acetyltransferase; gamma-Aminobutyric Acid; Immunohistochemistry; Muscimol; Retina; Tritium | 1988 |
Physostigmine induces in rats a phenomenon resembling long-term potentiation.
Topics: Acetylcholine; Animals; Bicuculline; Electric Stimulation; Electrophysiology; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Muscimol; Physostigmine; Rats; Rats, Inbred Strains; Scopolamine | 1988 |
[Ontogeny of GABAergic modulation on locomotor activity and pain reactivity in mice].
Topics: Animals; Brain; Drug Tolerance; Female; gamma-Aminobutyric Acid; Male; Mice; Motor Activity; Muscimol; Pain | 1988 |
The effect of Triton X-100 on bovine brain synaptic membranes.
Topics: Animals; Brain Chemistry; Calmodulin; Cattle; gamma-Aminobutyric Acid; Microscopy, Electron; Muscimol; Octoxynol; Polyethylene Glycols; Synaptosomes; Trypsin | 1988 |
Involvement of GABA in environmental temperature-induced change in body temperature.
Topics: 3-Mercaptopropionic Acid; Animals; Bicuculline; Body Temperature; Ethanolamines; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Temperature | 1988 |
Interaction between GABAergic neurotransmission and rat hypothalamic corticotropin-releasing hormone secretion in vitro.
Topics: Animals; Baclofen; Corticotropin-Releasing Hormone; Diazepam; gamma-Aminobutyric Acid; Hypothalamus; Male; Muscimol; Organ Culture Techniques; Rats; Rats, Inbred Strains; Serotonin | 1988 |
Inhibition of the voltage-dependent calcium currents in isolated frog sensory neurons by GABA-related agonistic compounds.
Topics: Animals; Baclofen; Barbiturates; Benzodiazepines; Calcium; Diazepam; gamma-Aminobutyric Acid; Ganglia, Spinal; In Vitro Techniques; Muscimol; Neurons, Afferent; Rana catesbeiana; Taurine | 1988 |
Benzodiazepine enhancement of gamma-aminobutyric acid-mediated chloride ion flux in rat brain synaptoneurosomes.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Brain; Carbolines; Chlorides; Clonazepam; Diazepam; Drug Synergism; Flurazepam; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rats, Inbred Strains; Synaptosomes | 1988 |
GABAergic mechanisms mediating rotational behavior in rats: differences between dorsal and ventral striatum.
Topics: Animals; Corpus Striatum; Dextroamphetamine; gamma-Aminobutyric Acid; Male; Motor Activity; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains | 1988 |
Circadian regulation of retinomotor movements: II. The role of GABA in the regulation of cone position.
Topics: Animals; Bicuculline; Circadian Rhythm; Dopamine; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Melatonin; Muscimol; Photoreceptor Cells; Picrotoxin; Xenopus laevis | 1988 |
A GABAergic mechanism in the posterior hypothalamus modulates baroreflex bradycardia.
Topics: Animals; Bradycardia; Cats; Electric Stimulation; gamma-Aminobutyric Acid; Hypothalamus; Hypothalamus, Posterior; Muscimol; Picrotoxin; Pressoreceptors; Rats; Rats, Inbred Strains | 1988 |
Delta-aminovaleric acid antagonizes the pharmacological actions of baclofen in the central nervous system.
Topics: Animals; Baclofen; Bicuculline; Drug Antagonism; Electric Stimulation; Female; gamma-Aminobutyric Acid; H-Reflex; Male; Muscimol; Muscle Contraction; Muscle Spasticity; Rabbits; Rats; Rats, Inbred Strains; Reflex, Monosynaptic; Spinal Cord; Valerates | 1988 |
Effect of nicotine on central GABAergic system.
Topics: Animals; Apomorphine; Corpus Striatum; gamma-Aminobutyric Acid; Limbic System; Male; Muscimol; Nicotine; Nucleus Accumbens; Rats; Rats, Inbred Strains | 1988 |
Reversible alterations of cerebral gamma-aminobutyric acid in pyrithiamine-treated rats: implications for the pathogenesis of Wernicke's encephalopathy.
Topics: Animals; Brain; Cerebellum; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Ketoglutarate Dehydrogenase Complex; Male; Muscimol; Pons; Pyridinium Compounds; Pyrithiamine; Rats; Rats, Inbred Strains; Thalamus; Wernicke Encephalopathy | 1988 |
The effects of GABA agonists and antagonists on rat gastric acid secretion.
Topics: Animals; Baclofen; Bicuculline; Deoxyglucose; GABA Antagonists; gamma-Aminobutyric Acid; Gastric Acid; Injections, Intraventricular; Male; Muscimol; Rats; Rats, Inbred Strains | 1988 |
GABAergic supersensitivity within the pars reticulata of the rat substantia nigra following chronic haloperidol administration.
Topics: Animals; gamma-Aminobutyric Acid; Glycine; Haloperidol; Male; Muscimol; Neurons; Rats; Rats, Inbred Strains; Substantia Nigra; Time Factors | 1987 |
Cerebral glucose utilization following striatal lesions: the effects of the GABA agonist, muscimol, and the dopaminergic agonist, apomorphine.
Topics: Animals; Apomorphine; Brain; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Glucose; Kainic Acid; Male; Muscimol; Rats; Rats, Inbred Strains | 1987 |
The emergence of GABA-accumulating neurons during retinal histogenesis in the embryonic chick.
Topics: Animals; Aspartic Acid; Chick Embryo; gamma-Aminobutyric Acid; Mitosis; Muscimol; Neurons; Retina; Retinal Ganglion Cells | 1987 |
Cerebral GABAergic control of arterial blood pressure and heart rate in diabetic rats.
Topics: Animals; Blood Glucose; Blood Pressure; Brain; Brain Stem; Diabetes Mellitus, Experimental; Dopamine; gamma-Aminobutyric Acid; Heart Rate; Hypothalamus; Injections, Intraventricular; Male; Muscimol; Rats; Rats, Inbred Strains | 1987 |
Postnatal development of transmitter systems: sexual differentiation of the GABAergic system and effects of muscimol.
Topics: Aging; Animals; Brain; Female; gamma-Aminobutyric Acid; Male; Maternal-Fetal Exchange; Muscimol; Pregnancy; Rats; Rats, Inbred Strains; Sex Differentiation | 1986 |
[Potentiation of acupuncture analgesia by GABA in the dorsal raphe nucleus].
Topics: 3-Mercaptopropionic Acid; Acupuncture Therapy; Animals; Bicuculline; Electric Stimulation Therapy; gamma-Aminobutyric Acid; Male; Muscimol; Nipecotic Acids; Pain; Raphe Nuclei; Rats; Sensory Thresholds; Transcutaneous Electric Nerve Stimulation | 1986 |
Is GABA an afferent transmitter in the vestibular system?
Topics: Afferent Pathways; Ambystoma mexicanum; Animals; Bicuculline; Electric Stimulation; Evoked Potentials, Auditory; GABA Antagonists; gamma-Aminobutyric Acid; Muscimol; Nerve Fibers; Picrotoxin; Vestibule, Labyrinth | 1987 |
Evidence for gamma-aminobutyric acid modulation of ovarian hormonal effects on luteinizing hormone secretion and hypothalamic catecholamine activity in the female rat.
Topics: alpha-Methyltyrosine; Animals; Baclofen; Bicuculline; Castration; Catecholamines; Epinephrine; Estradiol; Female; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Hypothalamus; Hypothalamus, Middle; Luteinizing Hormone; Methyltyrosines; Muscimol; Norepinephrine; Preoptic Area; Progesterone; Rats | 1986 |
GABA and gonadotropin secretion: evidence from in vitro studies on regulation of LHRH secretion.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Arginine Vasopressin; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Hypothalamus; In Vitro Techniques; Male; Median Eminence; Muscimol; Orchiectomy; Oxytocin; Rats | 1986 |
Role of the substantia nigra in the kindling model of limbic epilepsy.
Topics: Animals; Aspartic Acid; Epilepsy; gamma-Aminobutyric Acid; Kindling, Neurologic; Limbic System; Muscimol; N-Methylaspartate; Rats; Substantia Nigra | 1986 |
Catecholamine release within the striatum of the freely moving rat.
Topics: Animals; Behavior, Animal; Corpus Striatum; Dibenzocycloheptenes; Dizocilpine Maleate; Dopamine; gamma-Aminobutyric Acid; Male; Muscimol; Perfusion; Rats; Rats, Inbred Strains; Substantia Nigra; Sympathomimetics | 1986 |
Immunocytochemical and autoradiographic localization of GABAergic neurons in the goldfish retina.
Topics: Animals; Autoradiography; Cyprinidae; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glycine; Goldfish; Immunoenzyme Techniques; Muscimol; Neurons; Retina | 1987 |
Effect of GABAergic treatment on resting and stress-induced adrenocortical activities in the thalamic pigeon.
Topics: Adrenal Cortex; Animals; Bicuculline; Columbidae; Corticosterone; Electric Stimulation; Female; gamma-Aminobutyric Acid; Male; Muscimol; Stress, Psychological; Thalamus | 1986 |
gamma-Aminobutyric acid stimulates pituitary growth hormone secretion in the neonatal rat. A superfusion study.
Topics: Animals; Animals, Newborn; Bicuculline; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Growth Hormone; Hypothalamus; In Vitro Techniques; Kinetics; Muscimol; Perfusion; Picrotoxin; Pituitary Gland; Rats; Rats, Inbred Strains | 1987 |
Sodium-independent, bicuculline-sensitive [3H]GABA binding to isolated rat hepatocytes.
Topics: Animals; Bicuculline; Cell Membrane; Cell Separation; Electrophysiology; gamma-Aminobutyric Acid; Liver; Male; Muscimol; Rats; Rats, Inbred Strains; Sodium; Temperature; Time Factors; Tritium | 1987 |
Foot shock stress decreases chloride efflux from rat brain synaptoneurosomes.
Topics: Animals; Brain; Chlorides; Electroshock; gamma-Aminobutyric Acid; Male; Muscimol; Pentobarbital; Rats; Rats, Inbred Strains; Stress, Psychological; Synaptosomes | 1987 |
Uptake inhibitors potentiate gamma-aminobutyric acid-induced contractile responses in the isolated ileum of the guinea-pig.
Topics: Animals; Bicuculline; Female; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Muscle, Smooth; Picrotoxin; Sesterterpenes; Taurine | 1987 |
The interrelationship between superior colliculus and substantia nigra pars reticulata in programming movements of cats: a follow-up.
Topics: Animals; Brain Mapping; Cats; gamma-Aminobutyric Acid; Male; Muscimol; Picrotoxin; Psychomotor Performance; Substantia Nigra; Superior Colliculi | 1987 |
Suppression of oscillatory activity in crustacean pyloric neurons: implication of GABAergic inputs.
Topics: Animals; Electric Stimulation; Electrophysiology; gamma-Aminobutyric Acid; Histocytochemistry; Muscimol; Nephropidae; Neurons; Pyloric Antrum; Tetrodotoxin | 1987 |
Actions of gamma-aminobutyric acid on rat supraoptic nucleus neurosecretory neurones in vitro.
Topics: Action Potentials; Animals; Bicuculline; Electric Conductivity; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Male; Membrane Potentials; Muscimol; Neurons; Rats; Rats, Inbred Strains; Strychnine; Supraoptic Nucleus; Taurine | 1987 |
Injection of baclofen into the ventromedial hypothalamus stimulates gastric motility in the rat.
Topics: Animals; Atropine; Baclofen; gamma-Aminobutyric Acid; Gastrointestinal Motility; Hypothalamus, Middle; Male; Muscimol; Rats; Rats, Inbred Strains; Vagotomy | 1987 |
Depressor neurons in rabbit caudal medulla do not transmit the baroreceptor-vasomotor reflex.
Topics: Animals; Bicuculline; Blood Pressure; gamma-Aminobutyric Acid; Heart Rate; Kidney Medulla; Male; Muscimol; Pressoreceptors; Rabbits; Reference Values; Reflex; Sympathetic Nervous System; Vasomotor System | 1987 |
Effect of gamma-aminobutyric acid on neurally mediated contraction of guinea pig trachealis smooth muscle.
Topics: Acetylcholine; Animals; Baclofen; Furosemide; gamma-Aminobutyric Acid; Guinea Pigs; Hemicholinium 3; In Vitro Techniques; Muscimol; Muscle Contraction; Muscle, Smooth; Naloxone; Phentolamine; Propranolol; Trachea | 1987 |
[The role of the globus pallidus (GP) and nucleus accumbens (NAc) in the control of avoidance conditioning of rats].
Topics: Animals; Avoidance Learning; Dopamine; Female; gamma-Aminobutyric Acid; Globus Pallidus; Haloperidol; Male; Microinjections; Motor Activity; Muscimol; Nucleus Accumbens; Rats; Septal Nuclei | 1987 |
Selective enhancement of shock avoidance responding elicited by GABA blockade in the posterior hypothalamus of rats.
Topics: Animals; Avoidance Learning; Bicuculline; Electroshock; gamma-Aminobutyric Acid; Heart Rate; Hypothalamus; Hypothalamus, Posterior; Male; Muscimol; Rats; Rats, Inbred Strains; Strychnine | 1987 |
In vivo effects of gamma-aminobutyric acid on the urinary bladder contraction accompanying micturition.
Topics: Aminooxyacetic Acid; Animals; Diazepam; Electric Stimulation; gamma-Aminobutyric Acid; Hexamethonium Compounds; Male; Muscimol; Neurons, Efferent; Picrotoxin; Rats; Rats, Inbred Strains; Semicarbazides; Urinary Bladder; Urination | 1987 |
Noradrenergic rather than GABAergic processes as the common mediation of the antidepressant profile of GABA agonists and imipramine-like drugs in animals.
Topics: Animals; Antidepressive Agents; Brain; Depression; Disease Models, Animal; gamma-Aminobutyric Acid; Imipramine; Male; Muscimol; Norepinephrine; Penbutolol; Picrotoxin; Prazosin; Rats; Rats, Inbred Strains | 1987 |
gamma-Aminobutyric acid stimulates acid secretion from the isolated guinea pig stomach.
Topics: Animals; Bicuculline; gamma-Aminobutyric Acid; Gastric Acid; Gastric Mucosa; Guinea Pigs; Histamine; Male; Muscimol; Pirenzepine; Proglumide; Scopolamine; Stomach; Tetrodotoxin | 1987 |
Circling behavior in honey bees.
Topics: Acetylcholine; Action Potentials; Animals; Bees; Brain; GABA Antagonists; Gallamine Triethiodide; gamma-Aminobutyric Acid; Muscimol; Picrotoxin; Stereotyped Behavior | 1987 |
Inhibition of GABA uptake in the rat hippocampal slice.
Topics: Aminobutyrates; Animals; Extracellular Space; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Male; Membrane Potentials; Muscimol; Neural Conduction; Nipecotic Acids; Pyramidal Tracts; Rats; Sodium | 1986 |
Effect of GABAergic drugs in the behavioral 'despair' test in rats.
Topics: Acetates; Aminooxyacetic Acid; Animals; Baclofen; Behavior, Animal; Bicuculline; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Isoxazoles; Male; Motor Activity; Muscimol; Oxazoles; Picrotoxin; Rats | 1986 |
Behavioral function of GABA in the median raphe nucleus.
Topics: Animals; Bicuculline; Cyproheptadine; Dihydrotestosterone; GABA Antagonists; gamma-Aminobutyric Acid; Haloperidol; Lysergic Acid Diethylamide; Male; Motor Activity; Muscimol; Picrotoxin; Raphe Nuclei; Rats | 1986 |
A GABA-activated chloride-conductance not blocked by picrotoxin on spiny lobster neuromuscular preparations.
Topics: Action Potentials; Animals; Chlorides; Drug Resistance; gamma-Aminobutyric Acid; In Vitro Techniques; Ivermectin; Lactones; Muscimol; Nephropidae; Neuromuscular Junction; Picrotoxin; Species Specificity | 1986 |
Localization of 3H-GABA, -muscimol, and -glycine in goldfish retinas stained for glutamate decarboxylase.
Topics: Animals; Autoradiography; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glycine; Goldfish; Muscimol; Retina; Tritium | 1986 |
Asymmetric diffusion into the postsynaptic neuron: an extremely efficient mechanism for removing excess GABA from synaptic clefts on the Deiters' neurone plasma membrane.
Topics: Animals; Biological Transport; Cell Membrane; Diazepam; Diffusion; gamma-Aminobutyric Acid; Mathematics; Muscimol; Neurons; Picrotoxin; Rabbits; Sodium; Synapses; Vestibular Nuclei; Vestibular Nucleus, Lateral | 1986 |
Age-related substantia nigra-mediated seizure facilitation.
Topics: Animals; Animals, Newborn; gamma-Aminobutyric Acid; Muscimol; Rats; Rats, Inbred Strains; Seizures; Substantia Nigra | 1986 |
Effects of gamma-aminobutyric acid on isolated cone photoreceptors of the turtle retina.
Topics: Action Potentials; Animals; Bicuculline; Chlorides; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; Muscimol; Photoreceptor Cells; Picrotoxin; Time Factors; Turtles | 1986 |
A GABA cardiovascular mechanism in the dorsal raphe of the rat.
Topics: Animals; Blood Pressure; gamma-Aminobutyric Acid; Heart Rate; Male; Muscimol; Picrotoxin; Raphe Nuclei; Rats; Rats, Inbred Strains | 1986 |
Responses of hypoglossal and phrenic nerves to decreased respiratory drive in cats.
Topics: Animals; Cats; Chemoreceptor Cells; gamma-Aminobutyric Acid; Hypoglossal Nerve; Medulla Oblongata; Muscimol; Phrenic Nerve; Respiration; Respiration, Artificial; Temperature | 1986 |
Effects of GABA-mimetic drugs on turnover of histamine in the mouse brain.
Topics: Aminooxyacetic Acid; Animals; Baclofen; Brain; Brain Chemistry; gamma-Aminobutyric Acid; Histamine; Isoxazoles; Male; Methylhistamines; Methylhistidines; Mice; Muscimol | 1986 |
The actions of ivermectin on cultured chick spinal cord neurons.
Topics: Animals; Cells, Cultured; Chick Embryo; gamma-Aminobutyric Acid; Ivermectin; Membrane Potentials; Muscimol; Neurons; Spinal Cord | 1986 |
Effects of GABAergic drugs in vivo on high-affinity choline uptake in vitro in mouse hippocampal synaptosomes.
Topics: 3-Mercaptopropionic Acid; Aminocaproates; Animals; Choline; Cyclohexanecarboxylic Acids; gamma-Aminobutyric Acid; Hippocampus; Male; Mice; Mice, Inbred ICR; Muscimol; Synaptosomes; Vigabatrin | 1986 |
Gamma-aminobutyric acid and alcohol actions: neurochemical studies of long sleep and short sleep mice.
Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cerebellum; Chlorides; Diencephalon; Drug Synergism; Ethanol; Female; gamma-Aminobutyric Acid; Hippocampus; Mice; Muscimol; Pentobarbital; Sleep; Telencephalon | 1986 |
The effect of diazepam upon local cerebral glucose use in the conscious rat.
Topics: Animals; Autoradiography; Brain Chemistry; Deoxy Sugars; Deoxyglucose; Diazepam; Energy Metabolism; gamma-Aminobutyric Acid; Humans; Injections, Intravenous; Isoxazoles; Male; Muscimol; Rats; Rats, Inbred Strains | 1986 |
Delayed transneuronal death of substantia nigra neurons prevented by gamma-aminobutyric acid agonist.
Topics: Animals; Cell Survival; gamma-Aminobutyric Acid; Ibotenic Acid; Male; Muscimol; Nerve Degeneration; Neural Inhibition; Rats; Substantia Nigra | 1987 |
Evidence for GABA involvement in midbrain control of medullary neurons that modulate nociceptive transmission.
Topics: Action Potentials; Animals; Bicuculline; gamma-Aminobutyric Acid; Male; Medulla Oblongata; Morphine; Muscimol; Neural Pathways; Pain; Pain Measurement; Periaqueductal Gray; Picrotoxin; Rats; Rats, Inbred Strains | 1986 |
Effect of chronic administration of methamphetamine on the responsiveness of substantia nigra zona reticulata neurons to GABA or a GABA agonist in rats.
Topics: Animals; Electric Stimulation; gamma-Aminobutyric Acid; Male; Methamphetamine; Muscimol; Neurons; Rats; Rats, Inbred Strains; Substantia Nigra | 1986 |
Evidence for GABAergic inhibition of a hypothalamic sympathoexcitatory mechanism in anesthetized rats.
Topics: 3-Mercaptopropionic Acid; Animals; Bicuculline; Drug Interactions; gamma-Aminobutyric Acid; Hypothalamus; Isoniazid; Male; Muscimol; Neural Inhibition; Rats; Rats, Inbred Strains; Sympathetic Nervous System | 1987 |
GABAergic mechanisms in nucleus tractus solitarius alter blood pressure and vasopressin release.
Topics: Animals; Bicuculline; Blood Pressure; gamma-Aminobutyric Acid; Heart Rate; Male; Medulla Oblongata; Muscimol; Nipecotic Acids; Pressoreceptors; Proline; Rats; Rats, Inbred Strains; Vasopressins | 1987 |
Local and remote effects of intra-caudate administration of GABA-related drugs on Met-enkephalin release in the basal ganglia.
Topics: Animals; Baclofen; Basal Ganglia; Bicuculline; Calcium; Caudate Nucleus; Corpus Striatum; Egtazic Acid; Enkephalin, Methionine; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Potassium; Rats; Rats, Inbred Strains | 1985 |
GABAergic, dopaminergic and cholinergic interactions in perphenazine-induced catatonia in rats.
Topics: Animals; Bromocriptine; Catatonia; Dopamine; Drug Synergism; GABA Antagonists; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Muscimol; Parasympatholytics; Perphenazine; Piracetam; Rats; Rats, Inbred Strains; Scopolamine; Time Factors; Valproic Acid | 1985 |
Distribution of GABA binding site subtypes in rat pituitary gland.
Topics: Animals; Binding Sites; Cerebellum; Frontal Lobe; gamma-Aminobutyric Acid; Male; Muscimol; Pituitary Gland; Pituitary Gland, Anterior; Pituitary Gland, Posterior; Rats | 1986 |
Dopaminergic regulation of cone retinomotor movement in isolated teleost retinas: II. Modulation by gamma-aminobutyric acid and serotonin.
Topics: Adaptation, Physiological; Animals; Cobalt; Dark Adaptation; Dopamine; Fishes; GABA Antagonists; gamma-Aminobutyric Acid; Light; Melatonin; Movement; Muscimol; Photoreceptor Cells; Pigment Epithelium of Eye; Retina; Serotonin; Synapses | 1986 |
Uptake and autoreceptor-controlled release of [3H]-GABA by the hypothalamic median eminence and pituitary neurointermediate lobe.
Topics: Animals; Arginine Vasopressin; Calcium; Dopamine; gamma-Aminobutyric Acid; Male; Median Eminence; Muscimol; Pituitary Gland, Anterior; Potassium; Rats; Rats, Inbred Strains; Serotonin | 1986 |
Central action of gamma-aminobutyric acid ligands to alter basal water and electrolyte absorption in the rat ileum.
Topics: Animals; Bicuculline; Biological Transport; Body Fluids; Cholinergic Fibers; Electrolytes; GABA Antagonists; gamma-Aminobutyric Acid; Ileum; Intestinal Absorption; Ligands; Male; Muscimol; Oxazoles; Parasympathetic Nervous System; Rats; Rats, Inbred Strains; Receptors, Cholinergic | 1985 |
Deficits in manipulative behaviors induced by local injections of muscimol in the first somatosensory cortex of the conscious monkey.
Topics: Animals; Brain Diseases; Brain Mapping; Female; gamma-Aminobutyric Acid; Hand; Macaca; Motor Skills; Muscimol; Oxazoles; Somatosensory Cortex | 1985 |
The mesencephalic locomotor region in cat: effects of local applications of diazepam and gamma-aminobutyric acid.
Topics: Animals; Cats; Cerebral Decortication; Diazepam; gamma-Aminobutyric Acid; Locomotion; Muscimol; Picrotoxin; Reaction Time; Reflex; Tegmentum Mesencephali | 1985 |
Caudal ventrolateral medulla can alter vasopressin and arterial pressure.
Topics: Animals; Arginine Vasopressin; Bicuculline; Blood Pressure; Brain Mapping; Electric Stimulation; gamma-Aminobutyric Acid; Male; Medulla Oblongata; Muscimol; Norepinephrine; Pituitary Gland, Posterior; Rabbits; Vasomotor System | 1985 |
Comparison of release of endogenous dopamine and gamma-aminobutyric acid from rat caudate synaptosomes.
Topics: Acetylcholine; Animals; Calcium; Caudate Nucleus; Dopamine; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Potassium; Rats; Rats, Inbred Strains; Synaptosomes | 1985 |
Stability of the amino acid content of nerve endings after administration of gamma-aminobutyrate agonists and antagonists.
Topics: Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Baclofen; Bicuculline; Brain Chemistry; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Male; Mice; Muscimol; Nerve Endings; Picrotoxin; Synaptosomes | 1985 |
Influence of central chemoreceptor afferent inputs on respiratory muscle activity.
Topics: Animals; Cats; Chemoreceptor Cells; Cold Temperature; Diaphragm; Electromyography; Female; gamma-Aminobutyric Acid; Intercostal Muscles; Male; Medulla Oblongata; Muscimol; Nicotine; Tidal Volume | 1985 |
gamma-Aminobutyric acid- and benzodiazepine-induced modulation of [35S]-t-butylbicyclophosphorothionate binding to cerebellar granule cells.
Topics: Animals; Benzodiazepines; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Carbolines; Cerebellum; Diazepam; gamma-Aminobutyric Acid; Granulocytes; Muscimol; Picrotoxin; Rats; Sulfur Radioisotopes; Temperature | 1985 |
Enhanced depressor effect of muscimol in the DOCA/NaCl hypertensive rat: evidence for altered GABAergic activity in brain.
Topics: Animals; Bicuculline; Blood Pressure; Brain Chemistry; Clonidine; Desoxycorticosterone; Drug Interactions; Epinephrine; GABA Antagonists; gamma-Aminobutyric Acid; Hypertension; Injections, Intraventricular; Male; Muscimol; Norepinephrine; Rats; Sodium Chloride; Sympathetic Nervous System | 1985 |
Studies of the role of gamma-aminobutyric acid in the hypothalamic control of feed intake in sheep.
Topics: Animals; Bicuculline; Brain; Eating; gamma-Aminobutyric Acid; Hypothalamus; Male; Muscimol; Pentobarbital; Picrotoxin; Sheep | 1985 |
GABAergic mechanisms in antinociception.
Topics: Alkynes; Aminocaproates; Aminooxyacetic Acid; Analgesics; Animals; Baclofen; Bicuculline; Central Nervous System; gamma-Aminobutyric Acid; Isoxazoles; Mice; Muscimol; Pain; Rats; Stereoisomerism; Substance P; Synaptic Transmission; Vigabatrin | 1984 |
Distribution and characterization of the GABA receptors in the CNS of ataxic mutant mouse.
Topics: Animals; Ataxia; Binding, Competitive; Brain; gamma-Aminobutyric Acid; Kinetics; Mice; Mice, Neurologic Mutants; Muscimol; Organ Size; Receptors, Cell Surface; Receptors, GABA-A; Spinal Cord; Tissue Distribution | 1984 |
Somatic and dendritic actions of gamma-aminobutyric acid agonists and uptake blockers in the hippocampus in vivo.
Topics: Acetylcholine; Action Potentials; Animals; Dendrites; gamma-Aminobutyric Acid; Hippocampus; Isonicotinic Acids; Isoxazoles; Male; Muscimol; Rats; Synaptic Transmission | 1984 |
CL 218,872 binding to benzodiazepine receptors in rat spinal cord: modulation by gamma-aminobutyric acid and evidence for receptor heterogeneity.
Topics: Animals; Benzodiazepinones; Cerebral Cortex; Flumazenil; gamma-Aminobutyric Acid; Male; Muscimol; Pyridazines; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Spinal Cord | 1984 |
3H-ACh release from guinea pig gallbladder evoked by GABA through the bicuculline-sensitive GABA receptor.
Topics: Acetylcholine; Animals; Baclofen; Bicuculline; Choline; Female; Gallbladder; gamma-Aminobutyric Acid; Guinea Pigs; Hexamethonium Compounds; In Vitro Techniques; Male; Muscimol; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter | 1984 |
Functional and pharmacological differences between two types of GABA receptor on embryonic chick sensory neurons.
Topics: Animals; Baclofen; Bicuculline; Calcium; Chick Embryo; Chlorides; Culture Techniques; gamma-Aminobutyric Acid; Ganglia, Spinal; Ion Channels; Membrane Potentials; Muscimol; Neurons; Receptors, Cell Surface; Receptors, GABA-A; Sensory Receptor Cells; Synaptic Transmission | 1984 |
GABAergic agents as anticonvulsants in baboons with photosensitive epilepsy.
Topics: Aminocaproates; Animals; Anticonvulsants; Baclofen; Carbolines; Cerebral Cortex; Dose-Response Relationship, Drug; Epilepsies, Myoclonic; gamma-Aminobutyric Acid; Isoxazoles; Muscimol; Papio; Photic Stimulation; Receptors, Cell Surface; Receptors, GABA-A; Taurine; Vigabatrin | 1984 |
Characteristics and distribution of muscimol binding sites in cat visual cortex.
Topics: Animals; Autoradiography; Cats; gamma-Aminobutyric Acid; Isoxazoles; Kinetics; Muscimol; Oxazoles; Receptors, GABA-A; Tissue Distribution; Tritium; Visual Cortex | 1984 |
Progesterone and estrogens in rat brain: modulation of GABA (gamma-aminobutyric acid) receptor activity.
Topics: Animals; Brain; Estrogens; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Isoxazoles; Kinetics; Muscimol; Nerve Tissue Proteins; Olfactory Bulb; Progesterone; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Neurotransmitter | 1984 |
gamma-Aminobutyric acid receptor binding antagonism by the amidine steroid RU5135.
Topics: Androstanes; Animals; Azasteroids; Barbiturates; Benzodiazepines; Bicuculline; Binding, Competitive; Cerebral Cortex; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Membranes; Muscimol; Rats; Receptors, GABA-A; Steroids, Heterocyclic | 1984 |
GABA receptors mediate cerebral vasodilation in the unanesthetized goat.
Topics: Animals; Atropine; Blood Pressure; Brain; Female; gamma-Aminobutyric Acid; Goats; Muscimol; Picrotoxin; Receptors, GABA-A; Vascular Resistance; Vasodilation | 1984 |
Ontogenesis of muscimol binding sites in cat visual cortex.
Topics: Animals; Binding Sites; Cats; gamma-Aminobutyric Acid; Kinetics; Muscimol; Neural Inhibition; Oxazoles; Receptors, GABA-A; Visual Cortex | 1984 |
Gamma-aminobutyric acid and basal ganglia outflow pathways.
Topics: Animals; Basal Ganglia; Catalepsy; Disease Models, Animal; gamma-Aminobutyric Acid; Haloperidol; Humans; Locomotion; Muscimol; Neural Pathways; Posture; Rats; Stereotyped Behavior; Synaptic Transmission | 1984 |
A study of the mechanism of cerebral hyperexcitability after irradiation.
Topics: Animals; Cerebellum; Cysteamine; gamma-Aminobutyric Acid; Kinetics; Male; Mice; Muscimol; Radiation-Protective Agents; Receptors, GABA-A; Whole-Body Irradiation | 1984 |
In vitro characterization of benzodiazepine receptor agonists, antagonists, inverse agonists and agonist/antagonists.
Topics: Animals; Brain; Chlorides; Etazolate; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Muscimol; Rats; Receptors, GABA-A | 1984 |
Chemically activated channels in muscle and spinal cord.
Topics: Acetylcholine; Animals; Chlorides; gamma-Aminobutyric Acid; Ion Channels; Kinetics; Membrane Potentials; Muscimol; Neuromuscular Junction; Pentobarbital; Receptors, Cholinergic; Receptors, GABA-A; Spinal Cord; Stimulation, Chemical; Synaptic Transmission | 1984 |
gamma-Aminobutyric acid-ergic analgesia: implications for gamma-aminobutyric acid-ergic therapy for drug addictions.
Topics: Animals; Baclofen; Brain; Drug Tolerance; Endorphins; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Mice; Morphine; Morphine Dependence; Muscimol; Nociceptors; Rats; Receptors, GABA-A; Sensory Thresholds; Substance Withdrawal Syndrome; Substance-Related Disorders | 1984 |
Regulation of prolactin secretion during suckling: involvement of the hypothalamo-pituitary GABAergic system.
Topics: Animals; Caudate Nucleus; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hypothalamo-Hypophyseal System; Hypothalamus, Middle; Lactation; Median Eminence; Muscimol; Pregnancy; Prolactin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sucking Behavior | 1984 |
The neural substrates of apomorphine-stimulated locomotor activity following denervation of the nucleus accumbens.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Caudate Nucleus; Dopamine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Hydroxydopamines; Male; Motor Activity; Muscimol; Neurons, Efferent; Norepinephrine; Nucleus Accumbens; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, GABA-A; Septal Nuclei | 1984 |
The effects of avermectin and drugs related to acetylcholine and 4-aminobutyric acid on neurotransmission in Ascaris suum.
Topics: Acetylcholine; Animals; Anthelmintics; Ascaris; Curare; Electric Stimulation; gamma-Aminobutyric Acid; In Vitro Techniques; Ivermectin; Lactones; Motor Neurons; Muscimol; Piperazine; Piperazines; Synaptic Transmission | 1984 |
[Neurochemical pathology of GABAergic and cholinergic systems in Parkinson disease: an autopsy study].
Topics: Acetylcholine; Adult; Aged; Brain; Choline O-Acetyltransferase; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Male; Middle Aged; Muscimol; Parasympathetic Nervous System; Parkinson Disease; Quinuclidinyl Benzilate; Receptors, GABA-A | 1984 |
Some barbiturates enhance the effect of muscimol on dopamine turnover in the rat retina.
Topics: Animals; Barbital; Barbiturates; Convulsants; Dopamine; Drug Synergism; GABA Antagonists; gamma-Aminobutyric Acid; Light; Male; Methyltyrosines; Muscimol; Oxazoles; Pentobarbital; Phenobarbital; Picrotoxin; Rats; Retina; Sesterterpenes | 1980 |
Decreased convulsant potency of picrotoxin and pentetrazol and enhanced [3H]flunitrazepam cortical binding following stressful manipulations in rats.
Topics: Animals; Anti-Anxiety Agents; Cerebral Cortex; Diazepam; Flunitrazepam; GABA Antagonists; gamma-Aminobutyric Acid; Isoniazid; Male; Muscimol; Pentylenetetrazole; Picrotoxin; Rats; Seizures; Stress, Physiological; Thiosemicarbazones | 1980 |
A GABAergic influence on the light-induced increase in dopamine turnover in the dark-adapted rat retina in vivo.
Topics: Animals; Dark Adaptation; Dopamine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Light; Male; Methyltyrosines; Muscimol; Picrotoxin; Rats; Retina; Tyrosine 3-Monooxygenase | 1980 |
In vitro modulation by SQ 20009 and SQ 65396 of GABA receptor binding in rat CNS membranes.
Topics: Animals; Anti-Anxiety Agents; Brain; Etazolate; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Membranes; Muscimol; Nerve Tissue Proteins; Nicotinic Acids; Pyrazoles; Pyridines; Rats; Receptors, Cell Surface | 1980 |
Central actions of somatostatin.
Topics: Action Potentials; Animals; Brain; Cerebral Cortex; Corpus Striatum; gamma-Aminobutyric Acid; Hippocampus; Iontophoresis; Male; Muscimol; Neurons; Rats; Somatostatin; Synaptosomes | 1980 |
The role of gamma-aminobutyric acid in acute and chronic neuroleptic action.
Topics: Animals; Antipsychotic Agents; Apomorphine; Diazepam; Dopamine; gamma-Aminobutyric Acid; Humans; Male; Methylphenidate; Mice; Muscimol; Scopolamine; Stereotyped Behavior; Time Factors | 1980 |
Benzodiazepines and neurotransmitters.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Brain Chemistry; gamma-Aminobutyric Acid; Ionophores; Muscimol; Neuroblastoma; Neurons; Neurotransmitter Agents; Receptors, Drug | 1980 |
Autoradiographic localization of binding sites for [3H]gamma-aminobutyrate, [3H]muscimol,(+)[3H]bicuculline methiodide and [3H] flunitrazepam in cultures of rat cerebellum and spinal cord.
Topics: Animals; Animals, Newborn; Anti-Anxiety Agents; Autoradiography; Bicuculline; Binding Sites; Cells, Cultured; Cerebellum; Female; Fetus; Flunitrazepam; gamma-Aminobutyric Acid; Muscimol; Oxazoles; Pregnancy; Rats; Receptors, Drug; Spinal Cord; Tritium | 1980 |
Binding and uptake of the GABA analogue, 3H-muscimol, in the retinas of goldfish and chicken.
Topics: Animals; Autoradiography; Chickens; gamma-Aminobutyric Acid; Goldfish; Muscimol; Neurons; Neurotransmitter Agents; Oxazoles; Receptors, Cell Surface; Receptors, GABA-A; Retina | 1980 |
Inhibition by arylsulphatase A of Na-independent [3H]-GABA and [3H]-muscimol binding to bovine cerebellar synaptic membranes.
Topics: Animals; Brain; Cattle; Cerebellum; Cerebroside-Sulfatase; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Oxazoles; Sodium; Sulfatases; Synaptic Membranes | 1980 |
Localization of putative amino acid neurotransmitters in the human retina.
Topics: Aspartic Acid; Autoradiography; gamma-Aminobutyric Acid; Glycine; Humans; Muscimol; Neurotransmitter Agents; Retina | 1980 |
GABAergic mechanisms in blood pressure control. A pharmacological analysis in the rat.
Topics: Animals; Baclofen; Blood Pressure; Brain; Cardiovascular System; Dopamine; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Neurotransmitter Agents; Norepinephrine; Rats | 1980 |
The role of GABA in the regulation of the dopamine/tyrosine hydroxylase-containing neurons of the rat retina.
Topics: Animals; Dopamine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Muscimol; Neural Inhibition; Neurons; Photic Stimulation; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Retina; Synaptic Transmission; Tyrosine 3-Monooxygenase | 1981 |
Age-related alterations in neurotransmitter receptors: an electrophysiological and biochemical analysis.
Topics: Acetylcholine; Aging; Animals; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; Muscimol; Neural Inhibition; Neurons; Neurotransmitter Agents; Quinuclidinyl Benzilate; Rats; Rats, Inbred F344; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Muscarinic; Receptors, Neurotransmitter | 1981 |
Septal driving of hippocampal theta rhythm: a role for gamma-aminobutyrate in the effects of minor tranquillizers?
Topics: Amobarbital; Animals; Anti-Anxiety Agents; Bicuculline; Chlordiazepoxide; Dose-Response Relationship, Drug; Drug Antagonism; Electric Conductivity; gamma-Aminobutyric Acid; Hippocampus; Male; Muscimol; Picrotoxin; Rats; Septum Pellucidum | 1981 |
Effects of muscimol on the crayfish neuromuscular junction.
Topics: Animals; Astacoidea; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Kinetics; Membrane Potentials; Muscimol; Neuromuscular Junction; Oxazoles; Synapses | 1981 |
Interactions between GABA, dopamine, acetylcholine, and glutamate-containing neurons in the extrapyramidal and limbic systems.
Topics: Acetylcholine; Animals; Apomorphine; Cerebral Cortex; Corpus Striatum; Dopamine; Extrapyramidal Tracts; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Haloperidol; Kinetics; Limbic System; Muscimol; Neurons; Rats | 1981 |
gamma-Aminobutyric acid (GABA) receptor stimulation. II. Specificity of progabide (SL 76002) and SL 75102 for the GABA receptor.
Topics: Animals; Brain; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Ligands; Muscimol; Neurotransmitter Agents; Rabbits; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1982 |
Serotonin-induced depolarization of rat facial motoneurons in vivo: comparison with amino acid transmitters.
Topics: Action Potentials; Amino Acids; Animals; Facial Nerve; gamma-Aminobutyric Acid; Glycine; Male; Membrane Potentials; Motor Neurons; Muscimol; Neurotransmitter Agents; Rats; Serotonin | 1982 |
Anion-dependent modulation of [3H]muscimol binding and of GABA-stimulated [3H]flunitrazepam binding by picrotoxin and related CNS convulsants.
Topics: Animals; Anions; Anti-Anxiety Agents; Cerebral Cortex; Convulsants; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Oxazoles; Picrotoxin; Rats; Receptors, Drug; Receptors, GABA-A; Strychnine; Tubocurarine | 1982 |
Relative disposition of the GABA agonists THIP and muscimol in the brain of the rat.
Topics: Animals; Brain; gamma-Aminobutyric Acid; Isoxazoles; Male; Muscimol; Oxazoles; Rats; Rats, Inbred Strains; Time Factors | 1982 |
Effects of delta-aminolaevulinic acid, porphobilinogen and structurally related amino acids on 2-deoxy-glucose uptake in cultured neurons.
Topics: Aminolevulinic Acid; Animals; Brain; Chick Embryo; Deoxy Sugars; Deoxyglucose; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kainic Acid; Kinetics; Levulinic Acids; Muscimol; Neurons; Porphobilinogen | 1982 |
Intra-raphe benzodiazepines enhance rat locomotor activity: interactions with GABA.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Bicuculline; Brain Stem; Chlordiazepoxide; Dose-Response Relationship, Drug; Flurazepam; gamma-Aminobutyric Acid; Male; Midazolam; Motor Activity; Muscimol; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Synaptic Transmission | 1983 |
Synaptic chemistry associated with aberrant neuronal development in the reeler mouse.
Topics: Animals; Cerebellum; Choline O-Acetyltransferase; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Mice; Mice, Neurologic Mutants; Muscimol; Norepinephrine; Quinuclidinyl Benzilate; Synapses; Tyrosine 3-Monooxygenase | 1983 |
Effect of gamma-aminobutyric acid agonists, glycine, taurine and neuropeptides on acetylcholine release from the rabbit retina.
Topics: Acetylcholine; Animals; Baclofen; Electroretinography; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Muscimol; Neurotransmitter Agents; Photic Stimulation; Rabbits; Retina; Strychnine; Taurine | 1983 |
GABA receptor binding and hemodynamic responses to ICV GABA in adult spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Brain; gamma-Aminobutyric Acid; Heart Rate; Hemodynamics; Hexamethonium; Hexamethonium Compounds; Hypertension; Muscimol; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
The effects of chlormethiazole on single unit activity in rat brain; interactions with inhibitory and excitatory neurotransmitters.
Topics: Acetylcholine; Animals; Brain; Chlormethiazole; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Male; Muscimol; Neurotransmitter Agents; Rats; Rats, Inbred Strains | 1983 |
Supersensitivity of the GABA receptor in the frog spinal cord, as induced by kainic acid.
Topics: Animals; Electrophysiology; gamma-Aminobutyric Acid; In Vitro Techniques; Kainic Acid; Muscimol; Perfusion; Pyrrolidines; Rana catesbeiana; Receptors, Cell Surface; Receptors, GABA-A; Spinal Cord | 1983 |
Histamine-induced depression of serotoninergic dorsal raphe neurons: antagonism by cimetidine, a reevaluation.
Topics: Animals; Cimetidine; gamma-Aminobutyric Acid; Histamine; Histamine H2 Antagonists; Iontophoresis; Male; Muscimol; Neurons; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin | 1984 |
GABA induces functionally active low-affinity GABA receptors on cultured cerebellar granule cells.
Topics: Animals; Calcium; Cells, Cultured; Cerebellum; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Isoxazoles; Muscimol; Potassium; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1984 |
[Differences in the mechanism of the antihypoxic action of benzodiazepine receptor agonists and muscimol].
Topics: Animals; Anti-Anxiety Agents; Diazepam; Drug Evaluation, Preclinical; gamma-Aminobutyric Acid; Hypoxia; Ligands; Mice; Muscimol; Oxazoles; Receptors, GABA-A | 1984 |
Arginine-vasopressin enhances the responses of lateral septal neurons in the rat to excitatory amino acids and fimbria-fornix stimuli.
Topics: Amino Acids; Animals; Arginine Vasopressin; Aspartic Acid; Brain; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Male; Muscimol; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Synapses | 1984 |
Suriclone, a new anxiolytic of the cyclopyrrolone family: evidence for possible interference with GABAergic systems.
Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Binding, Competitive; Cats; Cerebellum; Chlordiazepoxide; Corpus Striatum; Cyclic GMP; Diazepam; Evoked Potentials; gamma-Aminobutyric Acid; Homovanillic Acid; In Vitro Techniques; Muscimol; Naphthyridines; Nitrazepam; Phenothiazines; Piperazines; Rats; Spinal Cord; Sulfur Compounds | 1984 |
Site of gamma-aminobutyric acid (GABA)-mediated inhibition of growth hormone secretion in the rat.
Topics: Afferent Pathways; Alkynes; Aminocaproates; Animals; Bicuculline; gamma-Aminobutyric Acid; Growth Hormone; Hypothalamus, Middle; Male; Median Eminence; Muscimol; Nerve Fibers; Rats; Rats, Inbred Strains; Receptors, GABA-A; Somatostatin | 1984 |
Pharmacological manipulations of the substantia innominata-cortical cholinergic pathway.
Topics: Animals; Basal Ganglia; Cerebral Cortex; Choline; Enkephalins; gamma-Aminobutyric Acid; Glutamates; Imipramine; Male; Muscimol; Neural Inhibition; Neural Pathways; Neurotransmitter Agents; Parasympathetic Nervous System; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Substantia Innominata | 1984 |
The role of GABA in the anticonflict action of sodium valproate and chlordiazepoxide.
Topics: Aminooxyacetic Acid; Animals; Anti-Anxiety Agents; Chlordiazepoxide; Conflict, Psychological; Drug Interactions; gamma-Aminobutyric Acid; Ion Channels; Male; Muscimol; Rats; Receptors, GABA-A; Synaptic Transmission; Valproic Acid | 1984 |
In vivo evidence for GABAergic control of serotonin release in the cat substantia nigra.
Topics: Animals; Cats; Caudate Nucleus; Female; gamma-Aminobutyric Acid; Male; Muscimol; Picrotoxin; Receptors, Cell Surface; Receptors, GABA-A; Serotonin; Substance P; Substantia Nigra; Tritium | 1981 |
Morphological and neurochemical characterization of individual retinal neurons: a combined Golgi and autoradiographic technique.
Topics: Animals; Autoradiography; Cats; gamma-Aminobutyric Acid; Golgi Apparatus; Microscopy, Electron; Muscimol; Neurons; Receptors, Cell Surface; Receptors, GABA-A; Retina; Staining and Labeling; Tritium | 1982 |
Behavioral and neurochemical differentiation of specific projections in the septal-hippocampal cholinergic pathway of the rat.
Topics: Acetylcholine; Animals; Cholinergic Fibers; Extinction, Psychological; gamma-Aminobutyric Acid; Hippocampus; Male; Muscimol; Rats; Septum Pellucidum; Substance P | 1984 |
Plasma growth hormone and prolactin response to dopaminergic GABAmimetic and cholinergic stimulation in Huntington's disease.
Topics: Adult; Apomorphine; Arecoline; Dopamine; Female; gamma-Aminobutyric Acid; Growth Hormone; Humans; Huntington Disease; Male; Muscimol; Oxazoles; Prolactin | 1983 |
Inhibition of GABA uptake potentiates the conductance increase produced by GABA-mimetic compounds on single neurones in isolated olfactory cortex slices of the guinea-pig.
Topics: Animals; Central Nervous System; Cerebral Cortex; Electric Stimulation; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Isonicotinic Acids; Muscimol; Neural Conduction; Neurons; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Olfactory Pathways; Proline; Sodium; Taurine | 1984 |
GABA receptor binding in cultured mammalian spinal cord neurons.
Topics: Animals; Bicuculline; Culture Techniques; gamma-Aminobutyric Acid; Mice; Muscimol; Neurons; Receptors, Neurotransmitter; Spinal Cord | 1980 |
GABA receptors in bovine cerebral blood vessels: binding studies with [3H]muscimol.
Topics: Animals; Binding, Competitive; Cattle; Cerebral Arteries; gamma-Aminobutyric Acid; Muscimol; Oxazoles; Pia Mater; Receptors, Neurotransmitter; Vasodilation | 1980 |
Modulation by GABA of cholinergic transmission in the striatum.
Topics: Acetylcholine; Animals; Cholinergic Fibers; Corpus Striatum; gamma-Aminobutyric Acid; Male; Muscimol; Neural Inhibition; Picrotoxin; Rats; Synaptic Transmission | 1980 |
GABAergic denervation of rat substantia nigra: functional and pharmacological properties.
Topics: Afferent Pathways; Animals; Corpus Striatum; Denervation; Dominance, Cerebral; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Isoniazid; Male; Muscimol; Rats; Receptors, Neurotransmitter; Stereotyped Behavior; Substantia Nigra | 1980 |
Effect of the GABA receptor agonist muscimol on regional cerebral blood flow in the rat.
Topics: Animals; Caudate Nucleus; Cerebellum; Cerebral Cortex; Cerebrovascular Circulation; Female; gamma-Aminobutyric Acid; Mesencephalon; Muscimol; Oxazoles; Rats; Receptors, Neurotransmitter; Thalamus | 1980 |
Autoradiographic localization of 3H-GABA and 3H-muscimol binding in rat cerebellar cultures.
Topics: Animals; Autoradiography; Binding Sites; Cerebellum; Culture Techniques; Dendrites; gamma-Aminobutyric Acid; Muscimol; Neurons; Oxazoles; Purkinje Cells; Rats; Receptors, Neurotransmitter | 1980 |
Substrate specificity of [3H]muscimol binding to a particulate fraction of a neuron-enriched culture of embryonic rat brain.
Topics: Animals; Binding, Competitive; Brain; Cells, Cultured; Embryo, Mammalian; gamma-Aminobutyric Acid; Kinetics; Muscimol; Neurons; Oxazoles; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1980 |
Autoradiographic localization of gamma-aminobutyric acid (GABA) receptors in the rat cerebellum.
Topics: Animals; Autoradiography; Cerebellum; gamma-Aminobutyric Acid; Kinetics; Male; Muscimol; Rats; Receptors, Neurotransmitter | 1980 |
Interactions of taurine and beta-alanine with central nervous system neurotransmitter receptors.
Topics: Alanine; Animals; beta-Alanine; Binding, Competitive; Brain; Diazepam; Dihydroalprenolol; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Membranes; Muscimol; Pineal Gland; Radioligand Assay; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Receptors, Cholinergic; Taurine | 1980 |
A site for the potentiation of GABA-mediated responses by benzodiazepines.
Topics: Afferent Pathways; Animals; Bicuculline; Drug Synergism; Flurazepam; gamma-Aminobutyric Acid; Ion Channels; Medulla Oblongata; Membrane Potentials; Muscimol; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter | 1980 |
Drug-induced alterations in neurotransmitter receptor binding and function.
Topics: 4-Aminobutyrate Transaminase; Animals; Behavior, Animal; Brain; Corpus Striatum; Female; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Rats; Receptors, Cell Surface; Receptors, Cholinergic; Receptors, Dopamine; Receptors, GABA-A; Receptors, Muscarinic; Receptors, Neurotransmitter; Spiperone; Synaptic Membranes | 1980 |
Pharmacological and biochemical evidence for an interaction between the benzodiazepine and GABA receptors.
Topics: Animals; Benzodiazepines; Binding Sites; Brain; Carrier Proteins; Chlorides; gamma-Aminobutyric Acid; Ionophores; Membrane Proteins; Muscimol; Rats; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Receptors, Neurotransmitter; Synaptic Membranes; Synaptic Transmission | 1980 |
Studies on benzodiazepine receptors.
Topics: Animals; Benzodiazepines; Binding Sites; Cerebral Cortex; Chlorides; Diazepam; gamma-Aminobutyric Acid; Ligands; Methyltransferases; Muscimol; Neural Inhibition; Phenytoin; Phospholipids; Rats; Receptors, Drug; Receptors, GABA-A; Receptors, Neurotransmitter | 1980 |
Two or more conformations of benzodiazepine receptors depending on GABA receptors and other variables.
Topics: Animals; Benzodiazepines; Bicuculline; Brain; Diazepam; gamma-Aminobutyric Acid; Macromolecular Substances; Male; Muscimol; Piperidines; Rats; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Receptors, Neurotransmitter; Structure-Activity Relationship; Synaptic Membranes | 1980 |
Identification of GABA neurons in rat cortical cultures by GABA uptake autoradiography.
Topics: Animals; Autoradiography; Cerebral Cortex; Culture Techniques; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Glycine; Muscimol; Neurons; Rats; Receptors, Neurotransmitter | 1980 |
The effects of pentobarbital and related compounds on frog motoneurons.
Topics: Amino Acids; Animals; Anura; Bicuculline; Chloralose; Chlordiazepoxide; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Motor Neurons; Muscimol; Pentobarbital; Phenobarbital; Phenytoin; Picrotoxin; Spinal Cord; Strychnine; Synaptic Transmission | 1980 |
Potentiation by intraventricular muscimol of the anticonflict effect of benzodiazepines.
Topics: Animals; Conditioning, Operant; Conflict, Psychological; Diazepam; Dose-Response Relationship, Drug; Drinking; Eating; Fear; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Muscimol; Oxazoles; Rats; Receptors, Neurotransmitter | 1980 |
Na+-independent binding of [3H]GABA and [3H]muscimol to a "microsomal" fraction, but not to a myelin fraction of rat brain; further evidence that glial elements do not possess GABA-receptors.
Topics: Animals; Brain; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Microscopy, Electron; Microsomes; Muscimol; Neuroglia; Oxazoles; Rats; Receptors, Neurotransmitter; Sodium; Tritium | 1980 |
The striatonigral GABA pathway: functional and neurochemical characteristics in rats with unilateral striatal kainic acid lesions.
Topics: Animals; Corpus Striatum; gamma-Aminobutyric Acid; Humans; Kainic Acid; Male; Muscimol; Neural Pathways; Rats; Receptors, Cell Surface; Receptors, GABA-A; Stereotyped Behavior; Substantia Nigra | 1980 |
Evidence for a GABAergic nigrothalamic pathway in the rat. I. Behavioural and biochemical studies.
Topics: Animals; gamma-Aminobutyric Acid; Male; Movement; Muscimol; Neural Pathways; Rats; Substantia Nigra; Synaptic Transmission; Thalamic Nuclei; Thalamus | 1980 |
Evidence for a GABAergic nigrothalamic pathway in the rat. II. Electrophysiological studies.
Topics: Animals; gamma-Aminobutyric Acid; Male; Muscimol; Neural Pathways; Neurons; Rats; Reaction Time; Substantia Nigra; Synaptic Transmission; Thalamus | 1980 |
Increase in striatal [3H]muscimol binding following intrastriatal injection of kainic acid: a denervation supersensitivity phenomenon.
Topics: Animals; Corpus Striatum; gamma-Aminobutyric Acid; Kainic Acid; Male; Microinjections; Muscimol; Muscle Denervation; Octoxynol; Oxazoles; Polyethylene Glycols; Pyrrolidines; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1980 |
Involvement of central GABA receptors in the regulation of the urinary bladder function of anaesthetized rats.
Topics: Animals; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Glycine; Levodopa; Male; Muscimol; Muscle Contraction; Rats; Receptors, Cell Surface; Urinary Bladder | 1980 |
Differential solubilization of gamma-aminobutyric acid receptive sites from membranes of mammalian brain.
Topics: Animals; Bicuculline; Binding Sites; Binding, Competitive; Cattle; Cell Membrane; Cerebral Cortex; gamma-Aminobutyric Acid; Kinetics; Muscimol; Neurons; Nipecotic Acids; Polyethylene Glycols; Receptors, Neurotransmitter; Sodium; Solubility | 1981 |
gamma-Aminobutyric acid receptors in brain postsynaptic densities.
Topics: Animals; Brain; Brain Chemistry; gamma-Aminobutyric Acid; Microscopy, Electron; Muscimol; Rats; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter; Synaptic Membranes | 1981 |
Competitive inhibition of gamma-aminobutyric acid receptor binding by N-2-hydroxyethylpiperazine-N'-2-e-ethanesulfonic acid and related buffers.
Topics: 4-Aminobutyrate Transaminase; Animals; Binding, Competitive; Buffers; GABA Antagonists; gamma-Aminobutyric Acid; HEPES; In Vitro Techniques; Male; Muscimol; Piperazines; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1981 |
Does glial uptake affect GABA responses? AN intracellular study on rat dorsal root ganglion neurones in vitro.
Topics: Animals; beta-Alanine; gamma-Aminobutyric Acid; Ganglia, Spinal; In Vitro Techniques; Isonicotinic Acids; Membrane Potentials; Muscimol; Neuroglia; Neurons; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1980 |
Inhibition of gamma-aminobutyric acid release by gamma-aminobutyric acid agonist drugs. Pharmacology of the gamma-aminobutyric acid autoreceptor.
Topics: Animals; Brain; Cell Membrane; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Potassium; Rats; Receptors, Cell Surface; Receptors, GABA-A; Synaptosomes | 1981 |
Kainic acid-induced lesion of rat retina: differential effect on cyclic GMP and benzodiazepine and GABA receptors.
Topics: Animals; Carrier Proteins; Cyclic GMP; Diazepam; gamma-Aminobutyric Acid; Glutamate Dehydrogenase; Intracellular Signaling Peptides and Proteins; Kainic Acid; Male; Muscimol; Pyrrolidines; Rats; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Retina | 1981 |
GABA and muscimol inhibit the release of prolactin from dispersed rat anterior pituitary cells.
Topics: Animals; Bicuculline; Dopamine; Female; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Oxazoles; Picrotoxin; Pituitary Gland, Anterior; Prolactin; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1981 |
The insensitivity of developing benzodiazepine receptors to chronic treatment with diazepam, GABA and muscimol in brain cell cultures.
Topics: Animals; Brain; Cell Membrane; Cells, Cultured; Diazepam; Female; Fetus; gamma-Aminobutyric Acid; Kinetics; Mice; Mice, Inbred C57BL; Muscimol; Oxazoles; Pregnancy; Receptors, Drug; Receptors, GABA-A; Receptors, Neurotransmitter | 1981 |
Localized binding of [3H]muscimol to synapses in chicken retina.
Topics: Animals; Autoradiography; Binding, Competitive; Chickens; gamma-Aminobutyric Acid; Microscopy, Electron; Muscimol; Oxazoles; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Retina; Synapses | 1981 |
GABA and muscimol open ion channels of different lifetimes on cultured mouse spinal cord cells.
Topics: Animals; Cells, Cultured; Electric Conductivity; Embryo, Mammalian; gamma-Aminobutyric Acid; Ion Channels; Kinetics; Membrane Potentials; Mice; Muscimol; Neurons; Oxazoles; Spinal Cord | 1981 |
GABAergic synapses in the goldfish retina: an autoradiographic study of 3H-muscimol and 3H-GABA binding.
Topics: Animals; Autoradiography; gamma-Aminobutyric Acid; Goldfish; Muscimol; Neurons; Oxazoles; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Muscarinic; Retina; Synapses; Visual Pathways | 1981 |
Supersensitivity of substantia nigra pars reticulata neurons to GABAergic drugs after striatal lesions.
Topics: Animals; Corpus Striatum; gamma-Aminobutyric Acid; Kainic Acid; Male; Muscimol; Neurons; Rats; Receptors, Cell Surface; Receptors, GABA-A; Substantia Nigra | 1981 |
Effects of some GABA-mimetic drugs on the antinociceptive activity of morphine and beta-endorphin in rats.
Topics: Analgesics; Animals; beta-Endorphin; Bicuculline; Drug Interactions; Endorphins; gamma-Aminobutyric Acid; Isonicotinic Acids; Male; Morphine; Muscimol; Nicotinic Acids; Nipecotic Acids; Rats | 1981 |
Different efficacies of d- and l-gamma-amino-beta-hydroxybutyric acids in GABA receptor and transport test systems.
Topics: Animals; Astacoidea; Biological Transport; Brain; Electric Conductivity; gamma-Aminobutyric Acid; Kinetics; Membrane Potentials; Mice; Muscimol; Neurons; Receptors, Cell Surface; Receptors, GABA-A; Stereoisomerism | 1981 |
Characterization of benzodiazepine and gamma-aminobutyric recognition sites and their endogenous modulators.
Topics: Animals; Benzodiazepines; Binding, Competitive; Carrier Proteins; Cell Membrane; Cerebral Cortex; Diazepam; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Kinetics; Male; Membrane Proteins; Membrane Transport Proteins; Molecular Weight; Muscimol; Nerve Tissue Proteins; Organic Anion Transporters; Phospholipids; Rats; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Solubility; Synaptic Membranes | 1981 |
Hindbrain GABA receptors influence parasympathetic outflow to the stomach.
Topics: Animals; Bicuculline; Cats; gamma-Aminobutyric Acid; Gastrointestinal Motility; Medulla Oblongata; Muscimol; Muscle Contraction; Muscle, Smooth; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter; Stomach | 1981 |
High affinity GABA receptors-autoradiographic localization.
Topics: Animals; Autoradiography; Brain; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Tissue Distribution; Tritium | 1981 |
Soluble gamma-aminobutyric acid and benzodiazepine receptors from rat cerebral cortex.
Topics: Animals; Benzodiazepines; Binding, Competitive; Cell Fractionation; Cerebral Cortex; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Mitochondria; Muscimol; Rats; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Solubility; Synaptosomes | 1981 |
Studies on the relationship of gamma-aminobutyric acid-stimulated diazepam binding and the gamma-aminobutyric acid receptor.
Topics: Animals; Brain; Cerebellum; Diazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Octoxynol; Polyethylene Glycols; Rats; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Sulfhydryl Reagents | 1981 |
Two types of gamma-aminobutyric acid receptor on embryonic sensory neurones.
Topics: Action Potentials; Animals; Baclofen; Chick Embryo; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Neurons, Afferent; Receptors, Cell Surface; Receptors, GABA-A | 1981 |
Respiratory depression produced by activation of GABA receptors in hindbrain of cat.
Topics: Animals; Bicuculline; Cats; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Male; Muscimol; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter; Respiration | 1981 |
3H-muscimol binding in synaptosomal fractions from bovine and developing rabbit retinas.
Topics: Animals; Binding, Competitive; Cattle; gamma-Aminobutyric Acid; Muscimol; Oxazoles; Rabbits; Receptors, Cell Surface; Receptors, GABA-A; Retina; Synaptic Transmission; Synaptosomes | 1981 |
Methyl mercury enhances [3H]diazepam binding in different areas of the rat brain.
Topics: Animals; Brain; Diazepam; gamma-Aminobutyric Acid; Male; Methylmercury Compounds; Muscimol; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, GABA-A; Retina; Spiperone | 1981 |
Ontogeny of high-affinity GABA and benzodiazepine receptors in the rat cerebellum: an autoradiographic study.
Topics: Aging; Animals; Autoradiography; Cerebellum; Clonazepam; Female; Flunitrazepam; gamma-Aminobutyric Acid; Muscimol; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A | 1981 |
GABA reduces binding of 3H-methyl beta-carboline-3-carboxylate to brain benzodiazepine receptors.
Topics: Animals; Bicuculline; Brain; Carbolines; Cerebellum; Cerebral Cortex; Diazepam; gamma-Aminobutyric Acid; Indoles; Muscimol; Rats; Receptors, Drug; Receptors, GABA-A; Structure-Activity Relationship | 1981 |
Glutamic acid decarboxylase and gamma-aminobutyric acid in Huntington's disease fibroblasts and other cultured cells, determined by a [3H]muscimol radioreceptor assay.
Topics: Carboxy-Lyases; Cells, Cultured; Fibroblasts; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Huntington Disease; Kinetics; Muscimol; Oxazoles; Radioligand Assay; Receptors, Cell Surface; Receptors, GABA-A; Skin | 1981 |
gamma-Aminobutyric acid- and benzodiazepine-binding sites in human anterior pituitary tissue.
Topics: Adult; Aged; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Humans; Isonicotinic Acids; Isoxazoles; Middle Aged; Muscimol; Pituitary Gland, Anterior; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A | 1982 |
gamma-Aminobutyric acid (GABA) receptor stimulation. IV. Effect of progabide (SL 76002) and other GABAergic agents on acetylcholine turnover in rat brain areas.
Topics: Acetylcholine; Animals; Brain; Corpus Striatum; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Synaptic Transmission | 1982 |
Some properties of solubilized GABA receptor.
Topics: Animals; Brain Chemistry; Chromatography, Gel; Diazepam; gamma-Aminobutyric Acid; Kinetics; Male; Methods; Molecular Weight; Muscimol; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, GABA-A; Receptors, Neurotransmitter | 1982 |
Acute and chronic effects of pentobarbital in relation to postsynaptic GABA receptors: a study with muscimol.
Topics: Animals; Brain; Drug Tolerance; gamma-Aminobutyric Acid; Humans; Male; Mice; Mice, Inbred ICR; Muscimol; Oxazoles; Pentobarbital; Receptors, Cell Surface; Receptors, GABA-A; Sleep; Substance Withdrawal Syndrome; Synaptic Membranes | 1982 |
Physicochemical characterization of detergent-solubilized gamma-aminobutyric acid and benzodiazepine receptor proteins from bovine brain.
Topics: Animals; Cattle; Centrifugation, Density Gradient; Cerebral Cortex; Chemical Phenomena; Chemistry, Physical; Chromatography, Gel; Deoxycholic Acid; Flunitrazepam; gamma-Aminobutyric Acid; Molecular Weight; Muscimol; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Solubility | 1982 |
Binding of [3H]gamma-aminobutyric acid and [3H]muscimol in purified rat brain synaptic plasma membranes and the effects of bicuculline.
Topics: Animals; Bicuculline; Binding, Competitive; Brain; gamma-Aminobutyric Acid; Male; Muscimol; Oxazoles; Rats; Receptors, Cell Surface; Receptors, GABA-A; Synaptic Membranes; Tritium | 1982 |
Postnatal development of the GABA system in the rat spinal cord.
Topics: Age Factors; Animals; Animals, Newborn; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Kinetics; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Spinal Cord | 1982 |
Single channel currents activated by gamma-aminobutyric acid, muscimol, and (-)-pentobarbital in cultured mouse spinal neurons.
Topics: Animals; Cells, Cultured; Embryo, Mammalian; gamma-Aminobutyric Acid; Ion Channels; Kinetics; Mice; Muscimol; Neurons; Oxazoles; Pentobarbital; Spinal Cord | 1982 |
Identification of gamma-aminobutyric acid and its binding sites in the rat ovary.
Topics: Animals; Brain Chemistry; Carboxy-Lyases; Diethylstilbestrol; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Male; Muscimol; Muscles; Ovary; Pituitary Gland; Radioligand Assay; Rats; Receptors, Drug; Receptors, GABA-A; Testis | 1982 |
Drugs that increase gamma-aminobutyric acid transmission protect against the high pressure neurological syndrome.
Topics: Anesthetics; Animals; Bicuculline; Body Temperature; Flurazepam; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred Strains; Muscimol; Pressure; Seizures; Synaptic Transmission; Tremor; Valproic Acid | 1982 |
(3H)-muscimol, (3H)-nipecotic acid and (3H)-isoguvacine as autoradiographic markers for GABA neurotransmission.
Topics: Animals; Autoradiography; gamma-Aminobutyric Acid; Goldfish; Guinea Pigs; Isonicotinic Acids; Muscimol; Neuroglia; Neurons; Nipecotic Acids; Oxazoles; Rabbits; Receptors, Cell Surface; Receptors, GABA-A; Retina; Synaptic Transmission | 1982 |
Actions of GABAergic agents on dopamine metabolism in the nigrostriatal pathway of the rat.
Topics: 4-Aminobutyrate Transaminase; Aminooxyacetic Acid; Animals; Corpus Striatum; Diazepam; Dopamine; GABA Antagonists; gamma-Aminobutyric Acid; Isoxazoles; Male; Muscimol; Neural Pathways; Pyrones; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Substantia Nigra | 1982 |
Evidence for a neuromodulatory role of GABA at the first synapse of the baroreceptor reflex pathway. Effects of GABA derivatives injected into the NTS.
Topics: Animals; Baclofen; Bicuculline; Blood Pressure; Cats; Female; gamma-Aminobutyric Acid; Heart Rate; Male; Medulla Oblongata; Muscimol; Pressoreceptors; Receptors, Cell Surface; Receptors, GABA-A; Reflex | 1982 |
GABA binding and bicuculline in spinal cord and cortical membranes from adult rat and from mouse neurons in cell culture.
Topics: Animals; Bicuculline; Cells, Cultured; Cerebral Cortex; gamma-Aminobutyric Acid; Mice; Muscimol; Neural Inhibition; Neurons; Rats; Receptors, Cell Surface; Receptors, GABA-A; Spinal Cord; Synaptic Membranes | 1982 |
Glycine antagonists structurally related to muscimol, THIP, or isoguvacine.
Topics: Animals; Cats; gamma-Aminobutyric Acid; Glycine; Interneurons; Isonicotinic Acids; Isoxazoles; Muscimol; Oxazoles; Rats; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Glycine; Spinal Cord; Structure-Activity Relationship | 1982 |
High specific binding of [3H]GABA and [3H]muscimol to membranes from dendrodendritic synaptosomes of the rat olfactory bulb.
Topics: Animals; Dendrites; gamma-Aminobutyric Acid; Male; Muscimol; Olfactory Bulb; Oxazoles; Rats; Receptors, Cell Surface; Receptors, GABA-A; Subcellular Fractions; Synaptic Membranes; Synaptosomes | 1982 |
Simultaneous recording of somatic and dendritic field potentials and combined microiontophoresis in the rat Ammon's horn in situ: effects of GABA and acetylcholine.
Topics: Acetylcholine; Animals; Dendrites; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; Male; Muscimol; Neural Inhibition; Neurons; Rats; Synaptic Transmission | 1982 |
Nigral output neurons are engaged in regulation of static fusimotor action onto flexors in cat.
Topics: Animals; Cats; gamma-Aminobutyric Acid; Motor Neurons; Motor Neurons, Gamma; Muscimol; Muscle Contraction; Muscle Spindles; Neurons, Afferent; Picrotoxin; Receptors, Neurotransmitter; Substantia Nigra | 1981 |
Medullary ventral surface GABA receptors affect respiratory and cardiovascular function.
Topics: Animals; Bicuculline; Blood Pressure; Cats; Female; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; Lung Volume Measurements; Male; Medulla Oblongata; Muscimol; Receptors, Cell Surface; Receptors, GABA-A; Respiration | 1982 |
Autoreceptors modify the evoked release of [3H]GABA from cerebellar neurons in dissociated cell culture.
Topics: Animals; Bicuculline; Cells, Cultured; Cerebellum; Fluspirilene; gamma-Aminobutyric Acid; Isoxazoles; Muscimol; Neurons; Potassium; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1982 |
Effects of agents which enhance GABA-mediated neurotransmission on licking conflict in rats and exploration in mice.
Topics: Animals; Conflict, Psychological; Diazepam; Exploratory Behavior; Flunitrazepam; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Nitrazepam; Rats; Rats, Inbred Strains; Synaptic Transmission; Urethane; Valproic Acid | 1982 |
Muscimol and some aza analogues: molecular orbital calculations relating to their potency as GABA mimetics.
Topics: Binding Sites; Chemical Phenomena; Chemistry; Electrons; gamma-Aminobutyric Acid; Humans; Molecular Conformation; Muscimol; Oxazoles; Pyrazoles; Pyrazolones; Receptors, Neurotransmitter; Rotation; Structure-Activity Relationship; Triazoles | 1982 |
Sodium valproate enhances responses to GABA receptor activation only at high concentrations.
Topics: Animals; Bicuculline; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Medulla Oblongata; Muscimol; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Tissue Distribution; Valproic Acid | 1982 |
Isolation of a GABA receptor from bovine brain using a benzodiazepine affinity column.
Topics: Animals; Cattle; Cell Membrane; Cerebral Cortex; Chromatography, Affinity; Clorazepate Dipotassium; Flunitrazepam; gamma-Aminobutyric Acid; Muscimol; Receptors, Cell Surface; Receptors, GABA-A | 1982 |
GABAergic modulation of ethanol-induced motor impairment.
Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminobutyrates; Aminocaproates; Animals; Bicuculline; Brain; Ethanol; gamma-Aminobutyric Acid; Isoxazoles; Male; Motor Skills; Muscimol; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1982 |
GABAergic regulation of the substantia innominata-cortical cholinergic pathway.
Topics: Acetylcholine; Animals; Brain; Cerebral Cortex; gamma-Aminobutyric Acid; Limbic System; Male; Muscimol; Parasympathetic Nervous System; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1982 |
Quantitative autoradiography of neurotransmitter receptors in Huntington disease.
Topics: Adult; Autoradiography; Brain; Female; Flunitrazepam; gamma-Aminobutyric Acid; Humans; Huntington Disease; Muscimol; Receptors, Amino Acid; Receptors, Drug; Receptors, GABA-A; Receptors, Muscarinic; Receptors, Neurotransmitter | 1982 |
Characterization of the solubilized GABA and benzodiazepine receptors from various regions of bovine brain.
Topics: Animals; Benzodiazepines; Brain; Brain Chemistry; Cattle; Cerebellum; Cerebral Cortex; Flunitrazepam; gamma-Aminobutyric Acid; Hippocampus; Molecular Weight; Muscimol; Organ Specificity; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
GABA 'desensitization' of frog primary afferent fibers.
Topics: Afferent Pathways; Amino Acids; Animals; Calcium; Dose-Response Relationship, Drug; Evoked Potentials; gamma-Aminobutyric Acid; Ion Channels; Muscimol; Nerve Fibers; Rana pipiens; Receptors, Cell Surface; Receptors, GABA-A; Spinal Cord; Synapses; Synaptic Transmission | 1982 |
Substantia nigra as a station that not only transmits, but also transforms, incoming signals for its behavioural expression: striatal dopamine and GABA-mediated responses of pars reticulata neurons.
Topics: Animals; Apomorphine; Behavior, Animal; Cats; Caudate Nucleus; Corpus Striatum; Dominance, Cerebral; Dopamine; Female; gamma-Aminobutyric Acid; Haloperidol; Hindlimb; Humans; Male; Motor Activity; Muscimol; Neural Pathways; Picrotoxin; Stereotyped Behavior; Substantia Nigra; Synaptic Transmission | 1983 |
Inactivation of GABA receptors by phenoxybenzamine: effects on GABA-stimulated benzodiazepine binding in the central nervous system.
Topics: Animals; Brain; gamma-Aminobutyric Acid; Male; Muscimol; Phenoxybenzamine; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Stimulation, Chemical; Time Factors | 1982 |
Comparison of centrifugation and filtration assays of ligand binding: do multiple GABA receptive sites exist?
Topics: Animals; Brain; Cattle; Centrifugation; Cerebral Cortex; Filtration; gamma-Aminobutyric Acid; Muscimol; Oxazoles; Receptors, Cell Surface; Receptors, GABA-A; Synaptic Membranes | 1982 |
Presence of GABA receptors in rat oviduct.
Topics: Animals; Bicuculline; Binding, Competitive; Cyclic AMP; Fallopian Tubes; Female; gamma-Aminobutyric Acid; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1982 |
Gabaergic regulation of nigrostriatal neurons: coupling of benzodiazepine and GABA receptors.
Topics: Animals; Corpus Striatum; Diazepam; Dopamine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Muscimol; Neural Inhibition; Neural Pathways; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Substantia Nigra | 1982 |
Molecular sizes of photolabeled GABA and benzodiazepine receptor proteins are identical.
Topics: Animals; Benzodiazepines; Cerebellum; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Muscimol; Rats; Receptors, Cell Surface; Receptors, GABA-A; Synaptosomes | 1983 |
Effect of acute and chronic cholinesterase inhibition with diisopropylfluorophosphate on muscarinic, dopamine, and GABA receptors of the rat striatum.
Topics: Acetylcholinesterase; Animals; Corpus Striatum; gamma-Aminobutyric Acid; Isoflurophate; Kinetics; Male; Muscimol; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Cholinergic; Receptors, Dopamine; Receptors, GABA-A; Receptors, Muscarinic | 1983 |
GABAA and GABAB receptor-mediated effects in guinea-pig ileum.
Topics: Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Muscle, Smooth; Receptors, Cell Surface; Receptors, GABA-A; Taurine | 1983 |
A gamma-aminobutyric acid/benzodiazepine receptor complex of bovine cerebral cortex.
Topics: Animals; Benzodiazepines; Cattle; Cerebral Cortex; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Macromolecular Substances; Molecular Weight; Muscimol; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Changes in [3H]muscimol binding in substantia nigra, entopeduncular nucleus, globus pallidus, and thalamus after striatal lesions as demonstrated by quantitative receptor autoradiography.
Topics: Animals; Autoradiography; Corpus Striatum; gamma-Aminobutyric Acid; Globus Pallidus; Kainic Acid; Male; Muscimol; Oxazoles; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter; Substantia Nigra; Thalamus | 1983 |
Modulation of GABA receptor binding by Ca2+.
Topics: Animals; Baclofen; Calcium; Cerebral Cortex; gamma-Aminobutyric Acid; Kinetics; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Synaptic Membranes | 1983 |
Bicuculline insensitive effects of baclofen.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Baclofen; Bicuculline; Corpus Striatum; gamma-Aminobutyric Acid; Male; Motor Activity; Muscimol; Oxazoles; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter | 1983 |
gamma-Aminobutyric acid and cholinergic transmission in the guinea-pig ileum.
Topics: Acetylcholine; Animals; Bicuculline; Electric Stimulation; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Muscimol; Muscle Contraction; Muscle, Smooth; Picrotoxin; Synaptic Transmission; Tritium | 1983 |
Differential sensitivity of ethanol withdrawal signs in the rat to gamma-aminobutyric acid (GABA)mimetics: blockade of audiogenic seizures but not forelimb tremors.
Topics: 4-Aminobutyrate Transaminase; Acoustic Stimulation; Aminobutyrates; Animals; Chlordiazepoxide; Disease Susceptibility; Ethanol; Forelimb; gamma-Aminobutyric Acid; Humans; Isoxazoles; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Seizures; Substance Withdrawal Syndrome; Tremor | 1983 |
Effects of glial uptake and desensitization on the activity of gamma-aminobutyric acid (GABA) and its analogs at the cat dorsal root ganglion.
Topics: Animals; Cats; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Ganglia, Spinal; Iontophoresis; Male; Membrane Potentials; Muscimol; Neuroglia; Neuromuscular Depolarizing Agents; Receptors, Cell Surface; Receptors, GABA-A; Taurine | 1983 |
Na+-dependent and Na+-independent binding of GABA in CNS subcellular particles--a search for GABA receptors.
Topics: Animals; Brain; Cattle; Cells, Cultured; gamma-Aminobutyric Acid; Mice; Muscimol; Rabbits; Rats; Receptors, Cell Surface; Receptors, GABA-A; Sodium; Subcellular Fractions | 1983 |
GABA as a trophic factor during development.
Topics: Animals; Animals, Newborn; gamma-Aminobutyric Acid; Isoxazoles; Muscimol; Nipecotic Acids; Proline; Rabbits; Receptors, Cell Surface; Receptors, GABA-A; Retina | 1983 |
Diazepam increases GABA mediated inhibition in the olfactory cortex slice.
Topics: Animals; Central Nervous System; Cerebral Cortex; Diazepam; Evoked Potentials; gamma-Aminobutyric Acid; Guinea Pigs; Intracellular Membranes; Membrane Potentials; Muscimol; Neural Inhibition; Olfactory Pathways; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Effects on eye movements of a GABA agonist and antagonist injected into monkey superior colliculus.
Topics: Animals; Bicuculline; Brain Mapping; Eye Movements; gamma-Aminobutyric Acid; Haplorhini; Muscimol; Saccades; Substantia Nigra; Superior Colliculi; Synaptic Transmission | 1983 |
Synaptic interactions in the GABA system during postnatal development in retina.
Topics: Animals; Cell Differentiation; gamma-Aminobutyric Acid; Muscimol; Nipecotic Acids; Proline; Rabbits; Receptors, Cell Surface; Receptors, GABA-A; Retina; Synaptic Transmission | 1983 |
[3H]muscimol binding site on purified benzodiazepine receptor.
Topics: Animals; Binding Sites; Brain; Flunitrazepam; gamma-Aminobutyric Acid; Molecular Weight; Muscimol; Oxazoles; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Effects of GABA receptor agonists on [3H] flunitrazepam binding to rat cerebellar and hippocampal membranes.
Topics: Animals; Cerebellum; Flunitrazepam; gamma-Aminobutyric Acid; Hippocampus; Imidazoles; Male; Membranes; Muscimol; Piperidines; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Diazepam stimulates the binding of GABA and muscimol but not THIP to rat brain membranes.
Topics: Analgesics; Animals; Brain; Diazepam; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Isoxazoles; Kinetics; Male; Muscimol; Oxazoles; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
The effects of chronic haloperidol administration on GABA receptor binding.
Topics: Animals; Apomorphine; Brain; Drug Administration Schedule; gamma-Aminobutyric Acid; Haloperidol; Humans; Kinetics; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Dopamine; Receptors, GABA-A; Stereotyped Behavior; Time Factors | 1983 |
Autoradiographic localization of binding sites for inhibitory amino acids and their antagonists in cultured rat CNS.
Topics: Amino Acids; Animals; Animals, Newborn; Autoradiography; Bicuculline; Brain Stem; Cells, Cultured; Cerebellum; Female; Fetus; Flunitrazepam; gamma-Aminobutyric Acid; Muscimol; Neuroglia; Neurons; Pregnancy; Rats; Receptors, Cell Surface; Spinal Cord; Tritium | 1983 |
The effects of kindling on GABA-mediated inhibition in the dentate gyrus of the rat. I. Paired-pulse depression.
Topics: Amygdala; Animals; Diazepam; gamma-Aminobutyric Acid; Hippocampus; Kindling, Neurologic; Male; Membrane Potentials; Muscimol; Neural Inhibition; Neural Pathways; Rats; Synaptic Transmission; Valproic Acid | 1983 |
The effects of kindling on GABA-mediated inhibition in the dentate gyrus of the rat. II. Receptor binding.
Topics: Amygdala; Animals; Brain; Flunitrazepam; gamma-Aminobutyric Acid; Hippocampus; Kindling, Neurologic; Male; Muscimol; Neural Inhibition; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Comparison of GABA analogues at the crayfish stretch receptor neurone.
Topics: Animals; Astacoidea; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Isoxazoles; Mechanoreceptors; Membrane Potentials; Muscimol; Nipecotic Acids; Proline; Sodium | 1983 |
Decreased high-affinity binding of [3H]muscimol to cerebral synaptic membranes of scrapie-infected mice.
Topics: Animals; Brain; Flunitrazepam; gamma-Aminobutyric Acid; Mice; Mice, Inbred C57BL; Muscimol; Oxazoles; Receptors, Cell Surface; Receptors, GABA-A; Scrapie; Sheep; Synaptic Membranes | 1984 |
The action of benzodiazepine antagonist Ro 15-1788 on the effects of GABA-ergic drugs.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aggression; Animals; Baclofen; Benzodiazepines; Benzodiazepinones; Brain Chemistry; Flumazenil; gamma-Aminobutyric Acid; Humans; Male; Motor Activity; Muscimol; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Role of the ventromedial nucleus of the thalamus in motor behaviour--I. Effects of focal injections of drugs.
Topics: Amino Acids; Amino Acids, Cyclic; Aminocaproates; Animals; Bicuculline; Corpus Striatum; Cyclohexanecarboxylic Acids; Flurazepam; gamma-Aminobutyric Acid; Humans; Male; Motor Activity; Muscimol; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Stereotyped Behavior; Substantia Nigra; Synaptic Transmission; Thalamic Nuclei; Vigabatrin | 1983 |
Ethanol and the gamma-aminobutyric acid-benzodiazepine receptor complex.
Topics: Animals; Benzodiazepinones; Brain; Carbolines; Ethanol; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Male; Membranes; Muscimol; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Temperature | 1984 |
Stress-induced enhancement of suppression of [3H]GABA release from striatal slices by presynaptic autoreceptor.
Topics: Aminolevulinic Acid; Animals; Corpus Striatum; gamma-Aminobutyric Acid; Male; Muscimol; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Stress, Physiological; Tetraethylammonium Compounds | 1984 |
Rat hippocampal neurons in culture: properties of GABA-activated Cl- ion conductance.
Topics: Animals; Cells, Cultured; Chlorides; Embryo, Mammalian; gamma-Aminobutyric Acid; Glycine; Hippocampus; Ion Channels; Membrane Potentials; Muscimol; Rats; Stimulation, Chemical | 1984 |
Saturable binding of 35S-t-butylbicyclophosphorothionate to the sites linked to the GABA receptor and the interaction with GABAergic agents.
Topics: Animals; Bicuculline; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Cerebral Cortex; gamma-Aminobutyric Acid; Male; Muscimol; Picrotoxin; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Sulfur Radioisotopes; Triazines | 1984 |
Increase in the Bmax of gamma-aminobutyric acid-A recognition sites in brain regions of mice receiving diazepam.
Topics: Animals; Brain; Cerebellum; Diazepam; gamma-Aminobutyric Acid; Isoniazid; Kinetics; Mice; Motor Activity; Muscimol; Organ Specificity; Rats; Receptors, Cell Surface; Receptors, GABA-A; Seizures | 1984 |
The ventral surface of the medulla in the rat: pharmacologic and autoradiographic localization of GABA-induced cardiovascular effects.
Topics: Animals; Autonomic Nervous System; Autoradiography; Bicuculline; Blood Pressure; Cardiovascular System; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Heart Rate; Male; Medulla Oblongata; Muscimol; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1984 |
Intranigral muscimol suppresses ethanol withdrawal seizures.
Topics: Acoustic Stimulation; Alcoholism; Animals; gamma-Aminobutyric Acid; Humans; Male; Muscimol; Oxazoles; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Seizures; Substance Withdrawal Syndrome; Substantia Nigra | 1984 |
A gamma-aminobutyric acid/benzodiazepine receptor complex from bovine cerebral cortex. Improved purification with preservation of regulatory sites and their interactions.
Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cerebral Cortex; Cholic Acids; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Methods; Muscimol; Pentobarbital; Receptors, Cell Surface; Receptors, GABA-A; Solubility | 1984 |
Diazotization and thiocyanate differentiate agonists from antagonists for the high- and low-affinity receptors of gamma-aminobutyric acid.
Topics: Androstanes; Animals; Azasteroids; Benzenesulfonates; Bicuculline; Cerebral Cortex; Diazonium Compounds; gamma-Aminobutyric Acid; Isoxazoles; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Sulfanilic Acids; Thiocyanates; Tubocurarine | 1984 |
[35S]-t-butylbicyclophosphorothionate binding sites are constituents of the gamma-aminobutyric acid benzodiazepine receptor complex.
Topics: Animals; Benzodiazepines; Binding Sites; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Cell Membrane; Cerebral Cortex; gamma-Aminobutyric Acid; Kinetics; Macromolecular Substances; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1984 |
Pharmacological analysis of the central cardiovascular effects of four GABA analogues.
Topics: Animals; Atropine; Bicuculline; Blood Pressure; Brain; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; Isonicotinic Acids; Isoxazoles; Kainic Acid; Muscimol; Pyrones; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1984 |
Intrinsic GABAergic system of adrenal chromaffin cells.
Topics: 4-Aminobutyrate Transaminase; Adrenal Medulla; Animals; Benzodiazepines; Biological Transport; Catecholamines; Cattle; Cell Membrane; Cells, Cultured; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Kinetics; Muscimol; Potassium Chloride; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Nicotinic | 1984 |
Blockade of GABA receptors in periventricular forebrain of anesthetized cats: effects on heart rate, arterial pressure, and hindlimb vascular resistance.
Topics: Adrenergic Fibers; Animals; Autonomic Nervous System; Bicuculline; Blood Pressure; Cats; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Heart Rate; Hindlimb; Injections, Intraventricular; Male; Muscimol; Paraventricular Hypothalamic Nucleus; Pressoreceptors; Receptors, Cell Surface; Receptors, GABA-A; Vascular Resistance | 1984 |
Characteristics of [3H] propyl beta-carboline-3-carboxylate binding to benzodiazepine receptors in human brain.
Topics: Binding, Competitive; Carbolines; Cations, Divalent; Cerebellum; Cerebral Cortex; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Halogens; Humans; In Vitro Techniques; Indoles; Male; Muscimol; Receptors, Cell Surface; Receptors, GABA-A | 1984 |
In vivo release of [3H]GABA in cat caudate nucleus and substantia nigra. II. Involvement of different thalamic nuclei in the bilateral changes induced by a nigral application of muscimol.
Topics: Animals; Cats; Caudate Nucleus; Dominance, Cerebral; Female; gamma-Aminobutyric Acid; Male; Muscimol; Neural Pathways; Neurons; Oxazoles; Substantia Nigra; Synaptic Transmission; Thalamic Nuclei | 1984 |
gamma-Aminobutyric acid directly depolarizes cultured oligodendrocytes.
Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Fluorescent Antibody Technique; gamma-Aminobutyric Acid; Membrane Potentials; Mice; Mice, Inbred Strains; Muscimol; Neuroglia; Oligodendroglia; Spinal Cord | 1984 |
Ro 15-1788 is a potent antagonist of benzodiazepines in the olfactory cortex slice.
Topics: Anesthetics; Animals; Benzodiazepines; Benzodiazepinones; Cerebral Cortex; Dose-Response Relationship, Drug; Flumazenil; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Muscimol | 1983 |
Effect of apomorphine and gabaergic drugs in monkeys pretreated with haloperidol.
Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Apomorphine; Chlorocebus aethiops; Female; gamma-Aminobutyric Acid; Haloperidol; Hemodynamics; Isoxazoles; Male; Motor Activity; Muscimol; Picrotoxin | 1983 |
Effects of GABA and some GABA analogues on respiratory regulation in the preterm rabbit.
Topics: Animals; Animals, Newborn; Carbon Dioxide; Depression, Chemical; gamma-Aminobutyric Acid; Gestational Age; Muscimol; Neurons; Rabbits; Respiration; Sodium Oxybate | 1983 |
Enhancement of spike and wave discharges by GABAmimetic drugs in rats with spontaneous petit-mal-like epilepsy.
Topics: Action Potentials; Aminocaproates; Animals; Baclofen; Epilepsy, Absence; gamma-Aminobutyric Acid; Isoxazoles; Muscimol; Rats; Vigabatrin | 1984 |
Increased cardiovascular responsiveness to GABAergic stimulation in DOCA-salt hypertensive rats.
Topics: 4-Aminobutyrate Transaminase; Animals; Blood Pressure; Brain; Desoxycorticosterone; Ethanolamines; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Heart Rate; Hemodynamics; Hypertension; Male; Muscimol; Nephrectomy; Phenylephrine; Rats; Rats, Inbred Strains; Valproic Acid | 1984 |
Effect of intrastriatal administration of cholinergic and GABAergic agonists on apomorphine-induced circling.
Topics: Animals; Apomorphine; Bicuculline; Corpus Striatum; Drug Interactions; gamma-Aminobutyric Acid; Humans; Injections; Male; Muscimol; Parasympathomimetics; Picrotoxin; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Scopolamine; Stereotyped Behavior | 1984 |
Chlordiazepoxide-induced hyperphagia in rats: lack of effect of GABA agonists and antagonists.
Topics: Animals; Chlordiazepoxide; Eating; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains | 1984 |
[Influence of the GABAergic system on eating behavior induced by the tail pinching technic in rats].
Topics: Animals; Energy Intake; Feeding Behavior; gamma-Aminobutyric Acid; Humans; Male; Muscimol; Oxazoles; Picrotoxin; Rats; Rats, Inbred Strains; Stress, Psychological; Valproic Acid | 1981 |
Autoradiographic studies of [3H]-glycine, [3H]-GABA, and [3H]-muscimol uptake in the mudpuppy retina.
Topics: Animals; Autoradiography; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Microscopy, Electron; Muscimol; Necturus; Oxazoles; Retina; Tritium | 1984 |
The bicuculline-like properties of dopamine sulfate in rat brain.
Topics: Animals; Bicuculline; Brain; Diazepam; Dopamine; Drug Interactions; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rats, Inbred Strains; Seizures; Strychnine; Synaptic Membranes | 1984 |
Synergistic anticonvulsant effects of a GABA agonist and glycine.
Topics: 3-Mercaptopropionic Acid; Animals; Anticonvulsants; Drug Synergism; gamma-Aminobutyric Acid; Glycine; Male; Mice; Muscimol; Oxazoles; Seizures | 1984 |
Feeding induced by injections of muscimol into the substantia nigra of rats: unaffected by haloperidol but abolished by large lesions of the superior colliculus.
Topics: Animals; Brain Mapping; Corpus Striatum; Dopamine; Feeding Behavior; gamma-Aminobutyric Acid; Haloperidol; Male; Muscimol; Neural Pathways; Oxazoles; Rats; Substantia Nigra; Superior Colliculi | 1984 |
Synaptic neurochemical alterations associated with neuronal degeneration in an inherited cerebellar ataxia of Gordon Setters.
Topics: Animals; Cerebellar Ataxia; Dogs; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Muscimol; Synapses | 1984 |
GABAergic agents in the medial septal nucleus affect hippocampal theta rhythm and acetylcholine utilization.
Topics: Acetylcholine; Animals; Bicuculline; gamma-Aminobutyric Acid; Hippocampus; Male; Muscimol; Neural Pathways; Oxazoles; Rats; Rats, Inbred Strains; Septal Nuclei; Theta Rhythm | 1984 |
Hyperpolarizing action of baclofen on neurons in the rat substantia nigra slice.
Topics: Animals; Baclofen; Bicuculline; Dopamine; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Potentials; Muscimol; Rats; Substantia Nigra | 1984 |
Effects of intraventricular injections of gamma-aminobutyric acid and related substances on feeding behavior in satiated sheep.
Topics: Animals; Drug Interactions; Feeding Behavior; gamma-Aminobutyric Acid; In Vitro Techniques; Injections, Intraventricular; Muscimol; Picrotoxin; Satiation; Sheep | 1984 |
GABA agonists inhibit the vasopressin-dependent pressor effects of central angiotensin II.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Brain; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Muscimol; Oxazoles; Rats; Rats, Inbred Strains; Sympathetic Nervous System | 1984 |
Self-injurious behavior in rats produced by intranigral microinjection of GABA agonists.
Topics: Animals; Baclofen; Bicuculline; Brain; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Isoxazoles; Male; Microinjections; Muscimol; Rats; Rats, Inbred Strains; Self Mutilation; Stress, Physiological; Substantia Nigra | 1984 |
GABAergic mechanisms in mediating muscular rigidity, catalepsy and postural asymmetry in rats: differences between dorsal and ventral striatum.
Topics: Animals; Catalepsy; Corpus Striatum; gamma-Aminobutyric Acid; Humans; Male; Muscimol; Muscle Rigidity; Posture; Rats; Rats, Inbred Strains; Substantia Nigra | 1984 |
The role of the GABA mechanisms of the globus pallidus in mediating catalepsy, stereotypy and locomotor activity.
Topics: Animals; Bicuculline; Brain Mapping; Catalepsy; Drug Interactions; gamma-Aminobutyric Acid; Globus Pallidus; Humans; Male; Motor Activity; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Stereotyped Behavior | 1984 |
In vivo release of [3H]GABA in cat caudate nucleus and substantia nigra. I. Bilateral changes induced by a unilateral nigral application of muscimol.
Topics: Animals; Brain Mapping; Cats; Caudate Nucleus; gamma-Aminobutyric Acid; Muscimol; Oxazoles; Substantia Nigra | 1983 |
Neuronal subpopulations in cat retina which accumulate the GABA agonist, (3H)muscimol: a combined Golgi and autoradiographic study.
Topics: Animals; Autoradiography; Cats; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Muscimol; Oxazoles; Retina | 1983 |
The influence of GABAergic drugs on PGO activity in the cat.
Topics: Alkynes; Aminocaproates; Animals; Brain; Cats; Chlordiazepoxide; Electroencephalography; Female; gamma-Aminobutyric Acid; Geniculate Bodies; Isoxazoles; Male; Muscimol; Occipital Lobe; Pons | 1983 |
Central cardiovascular action of penicillin in anaesthetized dogs and rats.
Topics: Adrenalectomy; Anesthesia; Animals; Blood Pressure; Clonidine; Dogs; Female; gamma-Aminobutyric Acid; Guanethidine; Heart Rate; Hemodynamics; Male; Muscimol; Penicillin G; Rats; Rats, Inbred Strains; Species Specificity | 1983 |
Diazepam potentiates GABA-, but not adenosine-mediated, inhibition of neurons of the nigral pars reticulata.
Topics: Adenosine; Adenosine Monophosphate; Animals; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Evoked Potentials; gamma-Aminobutyric Acid; Glycine; Male; Muscimol; Neural Inhibition; Neural Pathways; Neurons; Rats; Rats, Inbred Strains; Substantia Nigra | 1983 |
Unilateral injection of GABA agonists in the superior colliculus: asymmetry to tactile stimulation.
Topics: Analgesics; Animals; Baclofen; Functional Laterality; gamma-Aminobutyric Acid; Isoxazoles; Motor Activity; Muscimol; Oxazoles; Physical Stimulation; Rats; Rats, Inbred Strains; Superior Colliculi; Touch | 1983 |
Inhibition of drug-induced circling by GABA-ergic activity in the nucleus accumbens.
Topics: Animals; Brain Mapping; Dextroamphetamine; gamma-Aminobutyric Acid; Limbic System; Male; Muscimol; Nucleus Accumbens; Picrotoxin; Rats; Rats, Inbred Strains; Septal Nuclei | 1983 |
[New type of specific binding sites for gamma-aminobutyric acid (GABA) found in a mouse glioblastoma].
Topics: Animals; Binding Sites; Brain Neoplasms; Cell Line; Cells, Cultured; gamma-Aminobutyric Acid; Glioma; Mice; Muscimol | 1983 |
Effects of nigral application of muscimol on release of [3H] gamma-aminobutyrate and on multiunit activity in various cat thalamic nuclei.
Topics: Animals; Cats; gamma-Aminobutyric Acid; Muscimol; Oxazoles; Substantia Nigra; Thalamic Nuclei; Tritium | 1983 |
Involvement of preoptic-anterior hypothalamic GABA neurons in the regulation of pituitary LH and prolactin release.
Topics: Animals; Castration; Dopamine; Female; gamma-Aminobutyric Acid; Hypothalamus, Anterior; Hypothalamus, Middle; Luteinizing Hormone; Muscimol; Norepinephrine; Pituitary Gland; Preoptic Area; Prolactin; Rats; Rats, Inbred Strains | 1983 |
GABA-mediated inhibition of breathing in the late gestation sheep fetus.
Topics: Animals; Apnea; Female; Fetal Hypoxia; Fetus; gamma-Aminobutyric Acid; Gestational Age; Muscimol; Oxazoles; Picrotoxin; Pregnancy; Respiration; Sheep | 1983 |
Involvement of GABA in the antinociceptive effect of gamma-acetylenic GABA (GAG), an inhibitor of GABA-transaminase.
Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Analgesics; Animals; Baclofen; Bicuculline; Drug Interactions; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rats, Inbred Strains; Theophylline; Time Factors | 1983 |
Evidence that the nigrotegmental GABAergic projection mediates stereotypy induced by apomorphine and intranigral muscimol.
Topics: Animals; Apomorphine; Corpus Striatum; gamma-Aminobutyric Acid; Humans; Male; Muscimol; Neural Pathways; Oxazoles; Pons; Rats; Rats, Inbred Strains; Stereotyped Behavior; Substantia Nigra; Tegmentum Mesencephali | 1983 |
Extrastriatal circuits activated by intrastriatal muscimol: a [14C]2-deoxyglucose investigation.
Topics: Animals; Brain; Brain Mapping; Corpus Striatum; gamma-Aminobutyric Acid; Glucose; Male; Muscimol; Neural Pathways; Oxazoles; Rats; Rats, Inbred Strains | 1984 |
The effect of diazepam and of agents which change GABAergic functions in immobility in mice.
Topics: Aminooxyacetic Acid; Animals; Chlorpromazine; Diazepam; gamma-Aminobutyric Acid; Male; Mice; Motor Activity; Muscimol | 1984 |
Interactions of two phenylquinolines with picrotoxin and benzodiazepines in vivo and in vitro.
Topics: Animals; Anticonvulsants; Benzodiazepines; Drug Interactions; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Myoclonus; Pentylenetetrazole; Picrotoxin; Quinolines; Rats; Rats, Inbred Strains; Seizures | 1984 |
Growth hormone secretion of the neonatal rat pituitaries is stimulated by gamma-aminobutyric acid in vitro.
Topics: Aging; Animals; Animals, Newborn; Baclofen; Bicuculline; Diazepam; Female; GABA Antagonists; gamma-Aminobutyric Acid; Growth Hormone; In Vitro Techniques; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Strychnine | 1984 |
Differential effects of baclofen, gamma-hydroxybutyric acid and muscimol on the protective action of phenobarbital and diphenylhydantoin against maximal electroshock-induced seizures in mice.
Topics: Animals; Anticonvulsants; Baclofen; Drug Interactions; Electroshock; gamma-Aminobutyric Acid; Hydroxybutyrates; Injections, Intraventricular; Male; Mice; Muscimol; Oxazoles; Phenobarbital; Phenytoin; Sodium Oxybate | 1984 |
Nigral muscimol infusions facilitate the development of seizures in immature rats.
Topics: Age Factors; Animals; Flurothyl; gamma-Aminobutyric Acid; Muscimol; Oxazoles; Rats; Seizures; Substantia Nigra | 1984 |
Muscimol-scopolamine interactions in the rat brain: a study with 2-deoxy-D-[1-14C]glucose.
Topics: Animals; Brain; Deoxyglucose; gamma-Aminobutyric Acid; Glucose; Muscimol; Oxazoles; Rats; Rats, Inbred Strains; Scopolamine | 1984 |
Actions of gamma-aminobutyric acid on neurones of guinea-pig myenteric plexus.
Topics: Acetylcholine; Alanine; Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Glycine; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Muscimol; Myenteric Plexus; Neural Conduction; Neuromuscular Depolarizing Agents; Neurons; Nipecotic Acids; Picrotoxin; Proline; Tetrodotoxin | 1984 |
Involvement of catecholamines and glutamate in GABAergic mechanism regulatory to luteinizing hormone and prolactin secretion.
Topics: Animals; Biomechanical Phenomena; Catecholamines; Female; gamma-Aminobutyric Acid; Glutamates; Hypothalamus; Limbic System; Luteinizing Hormone; Muscimol; Prolactin; Rats | 1984 |
Circling behavior induced by intranigral injections of GABA and muscimol in rats.
Topics: Animals; Atropine; Behavior; Bicuculline; Brain Chemistry; Female; gamma-Aminobutyric Acid; Haloperidol; Humans; Injections; Muscimol; Oxazoles; Rats; Stereotyped Behavior; Strychnine; Substantia Nigra; Time Factors | 1980 |
Sodium di-n-propylacetate (valproate) potentiates responses to GABA and muscimol on single central neurones.
Topics: Animals; Dose-Response Relationship, Drug; Drug Synergism; Evoked Potentials; gamma-Aminobutyric Acid; Medulla Oblongata; Muscimol; Neurons; Oxazoles; Rats; Reticular Formation; Valproic Acid | 1980 |
Increase in striatal acetylcholine levels by GABAergic agents: dependence on corticostriatal neurons.
Topics: Acetylcholine; Animals; Cerebral Cortex; Corpus Striatum; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Muscimol; Neurons; Rats; Valproic Acid | 1980 |
The central GABAergic system and control of food intake under different experimental conditions.
Topics: Animals; Bicuculline; Brain; Ethanolamines; Feeding Behavior; Female; Food Deprivation; gamma-Aminobutyric Acid; Muscimol; Rats | 1980 |
Effects of sodium n-dipropylacetate, muscimol hydrobromide and (R,S) nipecotic acid amide on isolation-induced aggressive behavior in mice.
Topics: Aggression; Animals; gamma-Aminobutyric Acid; Humans; Male; Mice; Motor Activity; Muscimol; Nipecotic Acids; Oxazoles; Social Isolation; Time Factors; Valproic Acid | 1980 |
Discriminative stimulus effects of pentobarbital in pigeons.
Topics: Animals; Baclofen; Bemegride; Columbidae; Ethanol; gamma-Aminobutyric Acid; Muscimol; Pentobarbital; Prejudice | 1980 |
The effect of sodium-n-dipropyl acetate on gamma-aminobutyric acid-dependent inhibition in the rat cortex and substantia nigra in relation to its anticonvulsant activity.
Topics: Animals; Anticonvulsants; Cerebral Cortex; Electroshock; gamma-Aminobutyric Acid; Glycine; Male; Muscimol; Neurons; Rats; Substantia Nigra; Time Factors; Valproic Acid | 1980 |
Modulatory interactions between norepinephrine and taurine, beta-alanine, gamma-aminobutyric acid and muscimol, applied iontophoretically to cerebellar Purkinje cells.
Topics: Alanine; Animals; beta-Alanine; Cerebellum; Female; gamma-Aminobutyric Acid; Iontophoresis; Muscimol; Nerve Endings; Norepinephrine; Oxazoles; Purkinje Cells; Rats; Taurine | 1981 |
Involvement of the GABAergic system on shock-induced aggressive behavior in two strains of mice.
Topics: 4-Aminobutyrate Transaminase; Aggression; Allylglycine; Animals; Brain Chemistry; Dose-Response Relationship, Drug; Electroshock; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Muscimol; Picrotoxin; Stimulation, Chemical; Valproic Acid | 1981 |
Symptomatic treatment of tardive dyskinesia: a word of caution.
Topics: Animals; Brain; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Haplorhini; Humans; Levodopa; Muscimol; Rats; Receptors, Cholinergic; Receptors, Dopamine | 1981 |
Bicuculline, strychnine and depressant amino acid responses in the anteroventral cochlear nucleus of the cat.
Topics: Amino Acids; Animals; beta-Alanine; Bicuculline; Cats; Cochlea; Depression, Chemical; gamma-Aminobutyric Acid; Glycine; Muscimol; Strychnine; Taurine | 1982 |
[Protective effects of muscimol on acute brain ischemia in the rat (author's transl)].
Topics: Animals; Baclofen; gamma-Aminobutyric Acid; Ischemic Attack, Transient; Kinetics; Male; Muscimol; Oxazoles; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1982 |
Nigral actions of GABA agonists are enhanced by chronic fluphenazine and differentiated by concomitant flurazepam.
Topics: Animals; Baclofen; Bicuculline; Female; Fluphenazine; Flurazepam; gamma-Aminobutyric Acid; Humans; Isoxazoles; Muscimol; Rats; Rats, Inbred Strains; Stereotyped Behavior; Substantia Nigra | 1982 |
GABAergic influences on defensive fighting in rats.
Topics: Aggression; Aminocaproates; Animals; Baclofen; Bicuculline; Electroshock; gamma-Aminobutyric Acid; Humans; Male; Motor Activity; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Valproic Acid; Vigabatrin | 1982 |
Baclofen blocks postsynaptic inhibition but not the effect of muscimol in the olfactory cortex.
Topics: Animals; Baclofen; Cerebral Cortex; Drug Interactions; Electric Stimulation; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Muscimol; Neural Conduction; Neural Inhibition; Olfactory Pathways; Oxazoles; Synapses | 1983 |
GABA acts directly on cells of pituitary pars intermedia to alter hormone output.
Topics: Chlorides; gamma-Aminobutyric Acid; Melanocyte-Stimulating Hormones; Muscimol; Pituitary Gland; Potassium; Secretory Rate | 1983 |
GABA inhibition of central angiotensin II and hypertonic CSF pressor responses.
Topics: Angiotensin II; Animals; Blood Pressure; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Muscimol; Rats; Rats, Inbred Strains; Serotonin; Water-Electrolyte Balance | 1983 |
Gabaergic stimulation inhibits central actions of angiotensin II: pressor responses, drinking and release of vasopressin.
Topics: Aminooxyacetic Acid; Angiotensin II; Animals; Blood Pressure; Brain; Drinking; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Muscimol; Rats; Rats, Inbred Strains; Vasopressins | 1983 |
Effect of dopamine agonists on gamma-aminobutyric acid (GABA) turnover in the superior colliculus: evidence that nigrotectal GABA projections are under the influence of dopaminergic transmission.
Topics: Animals; Apomorphine; Bicuculline; Cocaine; Dextroamphetamine; Dopamine; gamma-Aminobutyric Acid; Male; Microinjections; Muscimol; Rats; Rats, Inbred Strains; Substantia Nigra; Superior Colliculi | 1983 |
Evidence that GABA and glycine-like inputs inhibit vasodepressor neurons in the caudal ventrolateral medulla of the rabbit.
Topics: Animals; Bicuculline; Blood Pressure; gamma-Aminobutyric Acid; Glycine; Heart Rate; Medulla Oblongata; Muscimol; Neural Inhibition; Neural Pathways; Neurons; Rabbits; Strychnine; Vasomotor System | 1983 |
Effects of barbiturates and ethanol on muscimol-induced release of [3H]-D-aspartate from rodent cerebellum.
Topics: Animals; Aspartic Acid; Cerebellum; Ethanol; gamma-Aminobutyric Acid; Kinetics; Male; Muscimol; Oxazoles; Pentobarbital; Potassium; Rats; Rats, Inbred Strains; Synaptosomes; Tritium | 1983 |
GABAergic drugs, morphine and morphine tolerance: a study in relation to nociception and gastrointestinal transit in mice.
Topics: Aminooxyacetic Acid; Analgesia; Animals; Baclofen; Bicuculline; Cyclohexanecarboxylic Acids; Digestion; Digestive System; Digestive System Physiological Phenomena; Drug Tolerance; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred ICR; Morphine; Muscimol; Naloxone; Nociceptors; Oxazoles; Picrotoxin | 1983 |
Differential effects of light and dark adaptations on function and metabolism of retinal taurine and gamma-aminobutyric acid (GABA).
Topics: Animals; Cell Membrane; Dark Adaptation; gamma-Aminobutyric Acid; Light; Muscimol; Rana catesbeiana; Retina; Taurine | 1981 |
Interaction of SQ 20009 and GABA-like drugs as modulators of benzodiazepine receptor binding.
Topics: Animals; Benzodiazepines; Cerebellum; Drug Interactions; Etazolate; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Membranes; Muscimol; Nicotinic Acids; Rats; Receptors, Drug | 1980 |
Evidence for a gamma-aminobutyric acid (GABA) mediation in the benzodiazepine inhibition of the release of Met5-enkephalin elicited by depolarization.
Topics: Animals; Benzodiazepines; Corpus Striatum; Endorphins; Enkephalin, Methionine; Enkephalins; gamma-Aminobutyric Acid; Glutamates; In Vitro Techniques; Isoniazid; Male; Membrane Potentials; Muscimol; Neprilysin; Potassium Chloride; Protease Inhibitors; Rats; Rats, Inbred Strains; Synaptic Membranes | 1982 |
Neuronal-like features of TE671 cells: presence of a functional nicotinic cholinergic receptor.
Topics: Acetylcholine; Action Potentials; Bungarotoxins; Cell Line; Cell Membrane; Cerebellar Neoplasms; gamma-Aminobutyric Acid; Humans; Kinetics; Medulloblastoma; Membrane Potentials; Muscimol; Neurons; Receptors, Cholinergic; Receptors, Nicotinic | 1982 |
The activity of cis and trans -2- (aminomethyl) cyclopropane carboxylic acids on GABA - related mechanisms in the central nervous system of Limulus and Periplanata and of mammals.
Topics: Animals; Binding, Competitive; Central Nervous System; Cockroaches; Cyclopropanes; gamma-Aminobutyric Acid; Horseshoe Crabs; In Vitro Techniques; Molecular Conformation; Muscimol; Neurons; Rats; Species Specificity; Synaptosomes | 1982 |
gamma-Aminobutyric acid action in guinea-pig ileal myenteric plexus.
Topics: Amino Acids; Animals; Atropine; Electric Stimulation; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscimol; Muscle, Smooth; Myenteric Plexus; Taurine; Tetrodotoxin | 1982 |
Biochemical characterization of isolated rat retinal cells: the gamma-aminobutyric acid system.
Topics: Animals; Cell Membrane; Cell Separation; Centrifugation, Density Gradient; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Metrizamide; Muscimol; Rats; Retina | 1982 |
Effects of the putative GABAergic agonists, muscimol and THIP, upon local cerebral glucose utilisation.
Topics: Analgesics; Animals; Brain; Deoxy Sugars; Deoxyglucose; gamma-Aminobutyric Acid; Glycolysis; Isoxazoles; Male; Muscimol; Organ Specificity; Oxazoles; Rats; Rats, Inbred Strains | 1982 |
Effects of gamma-aminobutyric acid agonist and antagonist drugs on local cerebral glucose utilization.
Topics: Animals; Autoradiography; Bicuculline; Brain; Carbon Radioisotopes; Deoxy Sugars; Deoxyglucose; gamma-Aminobutyric Acid; Glycolysis; Male; Muscimol; Organ Specificity; Oxazoles; Rats | 1982 |
GABA-ergic influence on the crossed extensor reflex.
Topics: Aminooxyacetic Acid; Animals; Benzodiazepines; Bicuculline; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rats, Inbred Strains; Reflex, Stretch | 1982 |
The TPc, the avian substantia nigra: pharmacology and behavior.
Topics: Animals; Apomorphine; Behavior, Animal; Biological Evolution; Brain Mapping; Columbidae; Female; gamma-Aminobutyric Acid; Haloperidol; Humans; Hydroxydopamines; Male; Muscimol; Substantia Nigra | 1982 |
On the involvement of GABA in the analgesia produced by baclofen, muscimol and morphine.
Topics: 4-Aminobutyrate Transaminase; Analgesia; Analgesics; Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Naloxone; Picrotoxin; Transaminases | 1982 |
Effects of GABA analogues and their interactions with morphine on locomotor activity in two inbred strains of mice.
Topics: Animals; Drug Interactions; gamma-Aminobutyric Acid; Isoxazoles; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Morphine; Motor Activity; Muscimol; Piracetam | 1982 |
In vivo modulations by GABA-related drugs of met-enkephalin release in basal ganglia of the cat brain.
Topics: Animals; Bicuculline; Cats; Caudate Nucleus; Diazepam; Drug Interactions; Enkephalin, Methionine; Female; gamma-Aminobutyric Acid; Globus Pallidus; Male; Muscimol; Picrotoxin | 1982 |
Substantia nigra: site of anticonvulsant activity mediated by gamma-aminobutyric acid.
Topics: Animals; Bicuculline; Brain Mapping; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Pentylenetetrazole; Rats; Seizures; Substantia Nigra | 1982 |
Differential localization of radioactive gamma-aminobutyric acid and muscimol in isolated and in vivo mouse retina.
Topics: Animals; Autoradiography; gamma-Aminobutyric Acid; In Vitro Techniques; Mice; Muscimol; Neuroglia; Oxazoles; Retina; Time Factors; Tissue Distribution | 1982 |
On the mechanism by which dopamine inhibits prolactin release in the anterior pituitary.
Topics: Animals; Bicuculline; Chlorpromazine; Depression, Chemical; Dopamine; gamma-Aminobutyric Acid; Haloperidol; Male; Mice; Mice, Inbred C57BL; Muscimol; Picrotoxin; Pituitary Gland, Anterior; Prolactin; Sesterterpenes | 1982 |
The use of gabaculine-induced accumulation of GABA for an index of synthesis of GABA in the retina.
Topics: Adaptation, Ocular; Animals; Bicuculline; Cyclohexanecarboxylic Acids; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rats, Inbred Strains; Retina | 1982 |
The ontogenesis of GABA mediated inhibition of growth hormone release in the sheep.
Topics: Animals; Animals, Newborn; Female; Fetus; gamma-Aminobutyric Acid; Growth Hormone; Muscimol; Picrotoxin; Pregnancy; Sheep | 1982 |
An in vivo method for testing GABAergic compounds.
Topics: Animals; Apomorphine; gamma-Aminobutyric Acid; Injections, Intraventricular; Injections, Subcutaneous; Male; Mice; Mice, Inbred ICR; Motor Activity; Muscimol; Oxazoles; Picrotoxin | 1982 |
Biphasic effects of direct, but not indirect, GABA mimetics and antagonists on haloperidol-induced catalepsy.
Topics: Allylglycine; Animals; Apomorphine; Behavior, Animal; Catalepsy; Drug Interactions; GABA Antagonists; gamma-Aminobutyric Acid; Haloperidol; Humans; Male; Muscimol; Rats; Stereotyped Behavior | 1980 |
GABA agonists dissociate striatal unit activity from drug-induced stereotyped behaviour.
Topics: Animals; Apomorphine; Corpus Striatum; Dextroamphetamine; gamma-Aminobutyric Acid; Humans; Male; Muscimol; Rats; Stereotyped Behavior | 1980 |
[GABA-ergic correlates of aggression and intraspecies sociability of mice subjected to isolation].
Topics: Aggression; Alkynes; Aminocaproates; Animals; Bicuculline; gamma-Aminobutyric Acid; Humans; Male; Mice; Mice, Inbred Strains; Muscimol; Picrotoxin; Semicarbazides; Social Behavior; Social Isolation | 1981 |
Removal of the telencephalon spares turning induced by injection of GABA agonists and antagonists into the substantia nigra.
Topics: Aminobutyrates; Animals; Baclofen; gamma-Aminobutyric Acid; Humans; Male; Muscimol; Neural Pathways; Picrotoxin; Rats; Rats, Inbred Strains; Stereotyped Behavior; Substantia Nigra; Telencephalon; Thalamus | 1980 |
Effect of GABA agonist and antagonists on cardiovascular and sympathetic responses in SHR and WKY rats.
Topics: Animals; Bicuculline; Cardiovascular Physiological Phenomena; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Picrotoxin; Rats; Sympathetic Nervous System | 1981 |
Mechanisms subserving the stimulatory and inhibitory components of gamma-aminobutyric acid-ergic control of prolactin secretion in the rat.
Topics: 4-Aminobutyrate Transaminase; Animals; Castration; Dihydrotestosterone; Estradiol; Ethanolamines; Female; gamma-Aminobutyric Acid; Hypothalamus; Kinetics; Male; Muscimol; Naloxone; Pituitary Gland; Pituitary Gland, Anterior; Pituitary Gland, Posterior; Prolactin; Rats | 1981 |
Increases and decreases in local cerebral glucose utilization in response to GABA agonists.
Topics: Animals; Brain; gamma-Aminobutyric Acid; Glucose; Isoxazoles; Male; Muscimol; Oxazoles; Rats | 1981 |
GABA and muscimol binding processes in CNS tissue culture preparations.
Topics: Animals; Astrocytes; Brain; Culture Media; Culture Techniques; gamma-Aminobutyric Acid; Mice; Muscimol; Neurons; Oxazoles; Rats | 1981 |
Autoradiographic localization of [3H]muscimol in the cat retina.
Topics: Animals; Autoradiography; Cats; gamma-Aminobutyric Acid; Microscopy, Electron; Muscimol; Neurons; Oxazoles; Retina; Tritium | 1981 |
Differential effects of sodium-free media on gamma-aminobutyrate and muscimol-evoked conductance increases recorded from lobster muscle fibres.
Topics: Animals; Dose-Response Relationship, Drug; Electric Conductivity; Evoked Potentials; gamma-Aminobutyric Acid; Kinetics; Lithium; Muscimol; Muscles; Nephropidae; Nipecotic Acids; Oxazoles; Sodium | 1981 |
Biochemical development of the human brain. II. Some parameters of the GABA-ergic system.
Topics: Adult; Aging; Cerebellum; Cerebral Cortex; DNA; Female; gamma-Aminobutyric Acid; Gestational Age; Glutamate Decarboxylase; Humans; Infant; Infant, Newborn; Muscimol; Pregnancy | 1981 |
Behavioural effects of GABA-agonists and antagonists infused in the mesencephalic reticular formation - deep layers of superior colliculus.
Topics: Animals; Behavior, Animal; Bicuculline; Dominance, Cerebral; gamma-Aminobutyric Acid; Mesencephalon; Motor Activity; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Reticular Formation; Seizures; Superior Colliculi | 1981 |
The nucleus tegmenti pedunculopontinus and circling behaviour in the rat.
Topics: Animals; Apomorphine; Autonomic Nervous System; Brain Mapping; Dopamine; gamma-Aminobutyric Acid; Kainic Acid; Locomotion; Male; Motor Activity; Muscimol; Neural Pathways; Posture; Rats; Rats, Inbred Strains; Substantia Nigra; Tegmentum Mesencephali | 1981 |
GABA in the entopeduncular nucleus and the subthalamic nucleus participates in mediating dopaminergic striatal output functions.
Topics: Animals; Behavior, Animal; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Injections, Intraventricular; Isoxazoles; Male; Mesencephalon; Muscimol; Neural Pathways; Picrotoxin; Rats; Rats, Inbred Strains; Thalamic Nuclei | 1981 |
Dose-conductance relationships for GABA agonists and the effect of uptake inhibitors in crayfish stretch receptor neurons.
Topics: Animals; Astacoidea; Dose-Response Relationship, Drug; Electric Conductivity; gamma-Aminobutyric Acid; Levodopa; Mechanoreceptors; Muscimol; Neurons | 1981 |
Etomidate stereospecifically stimulates forebrain, but not cerebellar, 3H-diazepam binding.
Topics: Animals; Brain; Cerebellum; Diazepam; Etomidate; Female; gamma-Aminobutyric Acid; Imidazoles; Isoxazoles; Muscimol; Rats; Rats, Inbred Strains; Stereoisomerism; Synaptic Membranes | 1981 |
GABA-ergic mechanisms in central respiratory control in the anesthetized rat.
Topics: Animals; Baclofen; Blood Gas Analysis; Blood Pressure; gamma-Aminobutyric Acid; Halothane; Heart Rate; Hydroxybutyrates; Injections, Intraventricular; Male; Muscimol; Rats; Rats, Inbred Strains; Respiration; Sodium Oxybate | 1981 |
Paradoxical blockade of a muscimol response by THIP, a GABA agonist and also by GABA-transaminase inhibitors.
Topics: 4-Aminobutyrate Transaminase; Animals; gamma-Aminobutyric Acid; Isoxazoles; Male; Mice; Muscimol; Myoclonus; Oxazoles; Time Factors; Transaminases | 1981 |
Evidence for the involvement of nigrothalamic GABA neurons in circling behaviour in the rat.
Topics: 4-Aminobutyrate Transaminase; Animals; Caudate Nucleus; Corpus Striatum; Electric Stimulation; Ethanolamines; Evoked Potentials; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Male; Motor Activity; Muscimol; Neurons; Picrotoxin; Rats; Rats, Inbred Strains; Thalamus | 1981 |
Single unit responses of substantia nigra and globus pallidus neurons to GABA agonist and antagonist drugs.
Topics: Animals; gamma-Aminobutyric Acid; Globus Pallidus; Iontophoresis; Isoxazoles; Kainic Acid; Male; Muscimol; Neurons; Oxazoles; Rats; Rats, Inbred Strains; Substantia Nigra | 1981 |
Taurine and thermoregulation: behavioral and cellular studies.
Topics: Animals; Behavior, Animal; Blood-Brain Barrier; Body Temperature Regulation; gamma-Aminobutyric Acid; Injections, Intraventricular; Muscimol; Muscle Tonus; Rabbits; Taurine; Time Factors | 1981 |
Decrease in effects of muscimol on the dorsal root after repeated administration of diazepam in rats.
Topics: Animals; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Male; Membrane Potentials; Muscimol; Oxazoles; Rats; Rats, Inbred Strains; Spinal Nerve Roots; Time Factors | 1981 |
Determination of GABA levels by a [3H]muscimol radioreceptor assay.
Topics: Animals; Binding, Competitive; Brain Chemistry; Cerebellum; Chromatography, Gas; gamma-Aminobutyric Acid; Kinetics; Male; Mice; Muscimol; Radioligand Assay; Rats; Tissue Distribution | 1980 |
Influence of gamma-aminobutyric acid on lordosis behavior and dopamine activity in estrogen primed spayed female rats.
Topics: Animals; Castration; Dopamine; Estradiol; Female; gamma-Aminobutyric Acid; Muscimol; Picrotoxin; Propionates; Rats; Septal Nuclei; Sexual Behavior, Animal; Substantia Nigra | 1980 |
Lack of Na"-independent binding of [3H]GABA or [3H]muscimol to particulate fractions of cultured astroblasts.
Topics: Animals; Astrocytes; Brain; Cells, Cultured; gamma-Aminobutyric Acid; Muscimol; Oxazoles; Radioligand Assay; Rats; Sodium; Tritium | 1980 |
Antagonism by penicillin of gamma-aminobutyric acid depolarizations at presynaptic sites in rat olfactory cortex and cuneate nucleus in vitro.
Topics: Action Potentials; Animals; Bicuculline; Cerebral Cortex; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Medulla Oblongata; Muscimol; Penicillin G; Penicillins; Picrotoxin; Rats; Synapses | 1980 |
Interaction between phencyclidine (PCP) and GABA-ergic drugs: clinical implications.
Topics: Aminooxyacetic Acid; Anesthesia; Animals; Baclofen; Dextroamphetamine; Diazepam; Drug Interactions; gamma-Aminobutyric Acid; Isoxazoles; Male; Mice; Motor Activity; Muscimol; Pain; Phencyclidine; Reflex | 1980 |
Effects of muscimol and picrotoxin on single unit activity of substantia nigra neurons.
Topics: Animals; Dose-Response Relationship, Drug; Electric Conductivity; gamma-Aminobutyric Acid; Male; Muscimol; Neurons; Oxazoles; Picrotoxin; Rats; Substantia Nigra | 1980 |
Release of endogenous amino acid neurotransmitter candidates from rat olfactory cortex slices: possible regulatory mechanisms and the effects of pentobarbitone.
Topics: Animals; Aspartic Acid; Dose-Response Relationship, Drug; Electric Stimulation; gamma-Aminobutyric Acid; Male; Muscimol; Olfactory Bulb; Pentobarbital; Picrotoxin; Rats; Taurine | 1980 |
Benzodiazepines modulate striatal enkephalin levels via a GABAergic mechanism.
Topics: Aminooxyacetic Acid; Animals; Bicuculline; Corpus Striatum; Diazepam; Endorphins; Enkephalin, Methionine; Enkephalins; Fentanyl; gamma-Aminobutyric Acid; Hypothalamus; Male; Muscimol; Radioimmunoassay; Rats | 1980 |
Intraneuronal effects of inhibitory amino acids.
Topics: Action Potentials; Aminoisobutyric Acids; Animals; Benzodiazepines; Cats; gamma-Aminobutyric Acid; Glycine; Membrane Potentials; Motor Neurons; Muscimol; Neuroglia; Sodium | 1980 |
Central nervous system mechanisms involving GABA influence arterial pressure and heart rate in the cat.
Topics: Animals; Autonomic Nervous System; Blood Pressure; Bradycardia; Cats; Central Nervous System; Clonidine; Female; gamma-Aminobutyric Acid; Heart Rate; Hypotension; Injections, Intraventricular; Male; Muscimol | 1980 |
Binding of [3H]GABA and [3H]muscimol to subcellular particles of a neurone-enriched culture of mouse brain.
Topics: Animals; Binding, Competitive; Brain; Cells, Cultured; Embryo, Mammalian; gamma-Aminobutyric Acid; Kinetics; Ligands; Mice; Muscimol; Neurons; Oxazoles; Protein Binding; Receptors, Drug; Tritium | 1980 |
In vivo release of endogenous gamma-aminobutyric acid from rat striatum: effects of muscimol, oxotremorine, and morphine.
Topics: Animals; Corpus Striatum; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Haloperidol; Male; Morphine; Muscimol; Nalorphine; Oxazoles; Oxotremorine; Potassium; Rats; Tetrodotoxin | 1980 |
An analysis of gamma-aminobutyrate receptors and uptake by isolated Purkinje cells.
Topics: Animals; Binding Sites; Biological Transport; Cattle; Cerebellum; gamma-Aminobutyric Acid; Kinetics; Microscopy, Electron, Scanning; Muscimol; Purkinje Cells; Receptors, Drug | 1980 |
Binding of muscimol and GABA in sub-fractions of a crude membrane fraction of rat brain.
Topics: Animals; Brain; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Oxazoles; Rats; Synaptic Membranes | 1980 |
The effect of GABAergic agents on opiate analgesia.
Topics: Animals; Drug Interactions; Endorphins; gamma-Aminobutyric Acid; Injections, Intraventricular; Isonicotinic Acids; Male; Morphine; Muscimol; Narcotics; Nicotinic Acids; Nipecotic Acids; Pain; Rats; Reaction Time; Time Factors | 1980 |
GABAergic actions of THIP in vivo and vitro: a comparison with muscimol and GABA.
Topics: Animals; Binding Sites; Brain; Cerebellum; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; In Vitro Techniques; Iontophoresis; Isoxazoles; Male; Muscimol; Neurons; Oxazoles; Rats; Substantia Nigra | 1980 |
Anorexic effects of ethanolamine-O-sulfate and muscimol in the rat: evidence that GABA inhibits ingestive behavior.
Topics: 4-Aminobutyrate Transaminase; Animals; Appetite Depressants; Body Weight; Brain Chemistry; Dextroamphetamine; Ethanolamines; Feeding Behavior; gamma-Aminobutyric Acid; Male; Motor Activity; Muscimol; Oxazoles; Rats | 1980 |
Effects of diazepam on GABA-evoked depolarization in rat dorsal root ganglia in vivo.
Topics: Animals; Diazepam; Drug Interactions; gamma-Aminobutyric Acid; Ganglia, Spinal; Male; Membrane Potentials; Muscimol; Rats; Time Factors | 1980 |
Some characteristics of [3H]muscimol binding to synaptic membrane from rat brain.
Topics: Animals; Binding Sites; Brain; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Muscimol; Oxazoles; Polyethylene Glycols; Rats; Synaptic Membranes; Temperature | 1980 |
Effects of thyroid state on brain development: muscarinic acetylcholine and GABA receptors.
Topics: Acetylcholine; Aging; Animals; Brain; Female; gamma-Aminobutyric Acid; Male; Muscimol; Quinuclidinyl Benzilate; Rats; Receptors, Cholinergic; Receptors, Muscarinic; Thyroid Hormones | 1980 |
Intravenous GABA agonist administration stimulates firing of A10 dopaminergic neurons.
Topics: Animals; Dopamine; gamma-Aminobutyric Acid; Injections, Intravenous; Isoxazoles; Limbic System; Muscimol; Neurons; Rats | 1980 |
Pharmacological blockade of the globus palidus-induced inhibitory response of subthalamic cells in the rat.
Topics: Animals; Bicuculline; gamma-Aminobutyric Acid; Globus Pallidus; Glutamates; Glycine; Male; Muscimol; Neurons; Picrotoxin; Rats; Strychnine; Synapses; Thalamus | 1980 |
Decreases in the binding of [3H]GABA and [3H]muscimol to a particulate fraction of rat brain produced by human sera; some speculations.
Topics: Animals; Blood Physiological Phenomena; Brain; gamma-Aminobutyric Acid; Male; Muscimol; Nerve Tissue Proteins; Oxazoles; Protein Binding; Rats; Synaptic Membranes | 1980 |
Neurons in cat lateral geniculate nucleus that concentrate exogenous [3H]-gamma-aminobutyric acid (GABA).
Topics: Animals; Autoradiography; Cats; gamma-Aminobutyric Acid; Geniculate Bodies; Microscopy, Electron; Muscimol; Neurons | 1980 |
[3H]Muscimol binding in the rat retina.
Topics: Animals; Binding Sites; Female; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Membranes; Muscimol; Octoxynol; Oxazoles; Polyethylene Glycols; Rats; Retina | 1980 |
GABA mediated circling from substantia nigra.
Topics: Dopamine; gamma-Aminobutyric Acid; Muscimol; Picrotoxin; Substantia Nigra | 1980 |
Evidence for the presence of a tonically active forebrain GABA system influencing central sympathetic outflow in the cat.
Topics: Animals; Bicuculline; Blood Pressure; Brain; Cats; Clonidine; Female; gamma-Aminobutyric Acid; Heart Rate; Male; Muscimol; Sympathetic Nervous System | 1980 |
Relationships between GABA and polyamines in developing rat brain.
Topics: 4-Aminobutyrate Transaminase; Adenosylmethionine Decarboxylase; Animals; Bicuculline; Brain; Brain Chemistry; gamma-Aminobutyric Acid; Muscimol; Ornithine Decarboxylase; Polyamines; Rats | 1980 |
Cardiovascular effects of intracerebroventricular GABA, glycine and muscimol in the rat.
Topics: Anesthesia; Animals; Dopamine; gamma-Aminobutyric Acid; Glycine; Hemodynamics; Injections, Intraventricular; Male; Muscimol; Oxazoles; Parasympathetic Nervous System; Rats; Serotonin; Sympathetic Nervous System | 1980 |
Effect of GABA analogues on blood pressure and central GABA metabolism in the rat.
Topics: 3-Mercaptopropionic Acid; Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Blood Pressure; Brain; Dopamine; gamma-Aminobutyric Acid; Heart Rate; Hydroxybutyrates; Male; Muscimol; Picrotoxin; Rats; Sodium Oxybate | 1980 |
Na+-independent binding of [3H]GABA and [3H]muscimol to subcellular particles of neural primary cultures and whole brain.
Topics: Animals; Animals, Newborn; Astrocytes; Binding Sites; Brain; Cells, Cultured; Embryo, Mammalian; gamma-Aminobutyric Acid; Muscimol; Oxazoles; Rats; Sodium | 1980 |
Dopamine receptor supersensitivity in the corpus striatum following chronic elevation of brain gamma-aminobutyric acid.
Topics: Alkynes; Aminocaproates; Aminooxyacetic Acid; Animals; Brain; Corpus Striatum; gamma-Aminobutyric Acid; Isoniazid; Kinetics; Male; Muscimol; Organ Specificity; Rats; Receptors, Dopamine | 1980 |
Anticonvulsant activity of muscimol and gamma-aminobutyric acid against pyridoxal phosphate-induced epileptic seizures.
Topics: Animals; Brain; Dose-Response Relationship, Drug; Epilepsy; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Injections, Intraventricular; Male; Muscimol; Pyridoxal Kinase; Pyridoxal Phosphate; Rats; Time Factors | 1981 |
Evidence for a tonic GABAergic control of serotonin neurons in the median raphe nucleus.
Topics: Animals; Bicuculline; Brain Stem; Diazepam; gamma-Aminobutyric Acid; Male; Muscimol; Neurons; Picrotoxin; Probenecid; Raphe Nuclei; Rats; Serotonin | 1981 |
Measurement of gamma-aminobutyric acid in human cerebrospinal fluid: radioreceptor assay using [3H]muscimol.
Topics: Animals; Cattle; gamma-Aminobutyric Acid; Humans; Muscimol; Oxazoles; Radioligand Assay; Tritium | 1981 |
Pharmacological subtypes of the gamma-aminobutyric acidA receptors defined by a gamma-aminobutyric acid analogue 4,5,6,7-tetrahydroisoxazolo[5,4-c] pyridin-3-ol and allosteric coupling: characterization using subunit-specific antibodies.
Topics: Allosteric Regulation; Amino Acid Sequence; Animals; Antibodies; Antibody Specificity; Benzodiazepines; Binding Sites; Binding, Competitive; Blotting, Western; Cattle; GABA Agonists; gamma-Aminobutyric Acid; Isoxazoles; Kinetics; Macromolecular Substances; Molecular Sequence Data; Muscimol; Precipitin Tests; Rabbits; Rats; Receptors, GABA-A; Sensitivity and Specificity; Sequence Homology, Amino Acid; Tritium | 1995 |
GABAA receptor needs two homologous domains of the beta-subunit for activation by GABA but not by pentobarbital.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cell Membrane; DNA Mutational Analysis; Female; gamma-Aminobutyric Acid; Ion Channels; Kinetics; Macromolecular Substances; Molecular Sequence Data; Muscimol; Mutagenesis, Site-Directed; Oocytes; Pentobarbital; Point Mutation; Rats; Receptors, GABA-A; Xenopus laevis | 1993 |
[Co-involvement of catecholaminergic and gabaergic transmission in the electro-cortical response to central galanin administration in the rabbit].
Topics: alpha-Methyltyrosine; Animals; Baclofen; Catecholamines; Ditiocarb; Drug Interactions; Electroencephalography; GABA Antagonists; Galanin; gamma-Aminobutyric Acid; Injections, Intraventricular; Methyltyrosines; Muscimol; Peptides; Rabbits; Synaptic Transmission | 1993 |
Chronic treatment with a classical neuroleptic alters excitatory amino acid and GABAergic neurotransmission in specific regions of the rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antipsychotic Agents; Autoradiography; Basal Ganglia; Basal Ganglia Diseases; Brain; Dizocilpine Maleate; Excitatory Amino Acids; Female; Fluphenazine; gamma-Aminobutyric Acid; Glutamate Decarboxylase; In Situ Hybridization; Muscimol; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stereotyped Behavior; Synaptic Transmission | 1994 |
GABAergic modulation of striatal peptide expression in rats and the alterations induced by dopamine antagonist treatment.
Topics: Animals; Baclofen; Benzazepines; Corpus Striatum; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Enkephalins; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamate Decarboxylase; Haloperidol; In Situ Hybridization; Male; Muscimol; Protein Precursors; Rats; Rats, Wistar; Receptors, GABA; RNA, Messenger; Salicylamides; Substance P; Tachykinins; Vigabatrin | 1994 |
Evidence that a GABAA-like receptor is involved in progesterone-induced acrosomal exocytosis in mouse spermatozoa.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acrosome; Animals; Bicuculline; Calcium Channels; Exocytosis; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Nifedipine; Progesterone; Receptors, GABA-A; Sperm Capacitation; Spermatozoa; Verapamil | 1995 |
Age-related differences in the effects of GABAA agonists microinjected into rat substantia nigra: pro- and anticonvulsant actions.
Topics: Age Factors; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Flurothyl; GABA Agonists; gamma-Aminobutyric Acid; Isoxazoles; Male; Microinjections; Muscimol; Rats; Rats, Sprague-Dawley; Seizures; Substantia Nigra | 1995 |
Exogenous GABA persistently opens Cl- channels in cultured embryonic rat thalamic neurons.
Topics: Animals; Cell Membrane; Cells, Cultured; Chloride Channels; Electric Conductivity; Embryo, Mammalian; gamma-Aminobutyric Acid; Membrane Potentials; Muscimol; Neurons; Rats; Thalamus | 1995 |
Chloride channel expression with the tandem construct of alpha 6-beta 2 GABAA receptor subunit requires a monomeric subunit of alpha 6 or gamma 2.
Topics: Affinity Labels; Azides; Base Sequence; Benzodiazepines; Binding Sites; Blotting, Northern; Cell Line; Chloride Channels; DNA, Complementary; gamma-Aminobutyric Acid; Gene Expression; Humans; Kidney; Kinetics; Macromolecular Substances; Membrane Potentials; Molecular Sequence Data; Muscimol; Oligodeoxyribonucleotides; Protein Multimerization; Receptors, GABA-A; Recombinant Proteins | 1995 |
A depolarizing inhibitory response to GABA in brainstem auditory neurons of the chick.
Topics: Animals; Baclofen; Basal Ganglia; Bicuculline; Brain Stem; Chickens; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Neuromuscular Depolarizing Agents; Neurons, Afferent; Patch-Clamp Techniques | 1995 |
Acute increase of GABAergic neurotransmission exerts a stimulatory effect on GnRH gene expression in the preoptic/anterior hypothalamic area of ovariectomized, estrogen- and progesterone-treated adult female rats.
Topics: Aminooxyacetic Acid; Animals; Baclofen; Estradiol; Female; gamma-Aminobutyric Acid; Gene Expression; Gonadotropin-Releasing Hormone; Hypothalamus; Hypothalamus, Anterior; Muscimol; Ovariectomy; Preoptic Area; Progesterone; Rats; Rats, Sprague-Dawley; RNA, Messenger; Synaptic Transmission | 1995 |
L-type Ca2+ channels mediate joint modulation by gamma-amino-butyric acid and glutamate of [Ca2+]i and neuropeptide secretion in immortalized gonadodropin-releasing hormone neurons.
Topics: Bicuculline; Calcium; Calcium Channels; Cell Line, Transformed; Cytoplasm; gamma-Aminobutyric Acid; Glutamic Acid; Gonadotropin-Releasing Hormone; Kainic Acid; Muscimol; N-Methylaspartate; Neurons; Neuropeptides; Potassium Chloride | 1995 |
Modulation of recombinant alpha 6 beta 2 gamma 2 GABAA receptors by neuroactive steroids.
Topics: Azides; Benzodiazepines; Binding, Competitive; Cell Line; Cells, Cultured; Electrophysiology; gamma-Aminobutyric Acid; Muscimol; Patch-Clamp Techniques; Receptors, GABA-A; Recombinant Proteins; Steroids | 1995 |
Non-length-tuned cells in layers II/III and IV of the visual cortex: the effect of blockade of layer VI on responses to stimuli of different lengths.
Topics: Animals; Cats; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Iontophoresis; Muscimol; Photic Stimulation; Visual Cortex | 1995 |
Ionic mechanisms of neuronal excitation by inhibitory GABAA receptors.
Topics: Acetazolamide; Amiloride; Animals; Bicarbonates; Chlorides; Dendrites; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Magnesium; Membrane Potentials; Muscimol; Neurons; Pyramidal Cells; Rats; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synapses | 1995 |
GABAergic stimulation switches from enhancing to repressing BDNF expression in rat hippocampal neurons during maturation in vitro.
Topics: Animals; Brain-Derived Neurotrophic Factor; Calcium; Cells, Cultured; gamma-Aminobutyric Acid; Gene Expression Regulation, Developmental; Hippocampus; Ion Channel Gating; Microscopy, Fluorescence; Muscimol; Nerve Growth Factors; Nerve Tissue Proteins; Neurons; Nifedipine; Proto-Oncogene Proteins c-fos; Rats; Receptors, GABA-A; RNA, Messenger | 1995 |
Direct and indirect effects of muscimol on medial vestibular nucleus neurones in guinea-pig brainstem slices.
Topics: Animals; Bicuculline; Brain Stem; Calcium; gamma-Aminobutyric Acid; Guinea Pigs; Magnesium; Muscimol; Neurons; Reflex, Vestibulo-Ocular; Vestibular Nuclei | 1995 |
Prenatal lorazepam exposure: 4. Persistent alterations in pentylenetetrazole-induced seizure threshold and GABA-dependent chloride uptake after prenatal lorazepam exposure.
Topics: Animals; Brain Chemistry; Chlorides; Chlorine; Female; gamma-Aminobutyric Acid; Lorazepam; Mice; Muscimol; Pentylenetetrazole; Pregnancy; Prenatal Exposure Delayed Effects; Radioisotopes; Seizures | 1995 |
Activation of metabotropic glutamate receptors produces reciprocal regulation of ionotropic glutamate and GABA responses in the nucleus of the tractus solitarius of the rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Electrophysiology; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Ibotenic Acid; Male; Medulla Oblongata; Muscimol; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Synapses | 1993 |
GABAA receptor-mediated inhibition of N-methyl-D-aspartate-evoked [3H]dopamine release from mesencephalic cell cultures.
Topics: Animals; Baclofen; Cells, Cultured; Dopamine; Flunitrazepam; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Kainic Acid; Mesencephalon; Muscimol; N-Methylaspartate; Picrotoxin; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, GABA; Ventral Tegmental Area | 1994 |
The role of mesoaccumbens--pallidal circuitry in novelty-induced behavioral activation.
Topics: Animals; Baclofen; Behavior, Animal; Dopamine; Dopamine Agonists; Exploratory Behavior; Fluphenazine; gamma-Aminobutyric Acid; Habituation, Psychophysiologic; Limbic System; Locomotion; Male; Microinjections; Muscimol; Neostriatum; Neural Pathways; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Substantia Nigra; Ventral Tegmental Area | 1995 |
Characterization of synaptic connections between cortex and deep nuclei of the rat cerebellum in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Cerebellar Nuclei; Cerebral Cortex; Electrophysiology; GABA Agonists; gamma-Aminobutyric Acid; In Vitro Techniques; Lysine; Muscimol; Neural Pathways; Purkinje Cells; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Synaptic Transmission; Tetrodotoxin; Vestibular Nucleus, Lateral | 1995 |
GABAA/benzodiazepine receptors in acutely isolated hippocampal astrocytes.
Topics: Amino Acid Sequence; Animals; Antibody Specificity; Astrocytes; Bicuculline; Brain; Calcium; Calcium Channels; Carbolines; Cell Separation; Chlorides; Diazepam; Evoked Potentials; gamma-Aminobutyric Acid; Gene Expression; Glial Fibrillary Acidic Protein; Hippocampus; Immunoblotting; In Vitro Techniques; Macromolecular Substances; Membrane Potentials; Molecular Sequence Data; Muscimol; Patch-Clamp Techniques; Peptide Fragments; Picrotoxin; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1995 |
GABAA receptor activation induces GABA and glutamate release from preoptic area.
Topics: Animals; Calcium; Female; Frontal Lobe; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Gonadal Steroid Hormones; Hypothalamus; Ion Channel Gating; Male; Muscimol; Nerve Endings; Neurotransmitter Agents; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1995 |
Dorsomedial hypothalamic GABA regulates anxiety in the social interaction test.
Topics: Animals; Anxiety; Atenolol; Atropine Derivatives; Bicuculline; Blood Pressure; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; Hypothalamus, Middle; Male; Microinjections; Muscimol; Parasympatholytics; Picrotoxin; Rats; Rats, Sprague-Dawley; Social Behavior | 1995 |
Effect of GABAergic compounds on gonadotropin-releasing hormone receptor gene expression in the rat.
Topics: Animals; Baclofen; Base Sequence; Brain; Cloning, Molecular; DNA Primers; DNA, Complementary; Female; GABA-A Receptor Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Gene Expression; Molecular Sequence Data; Muscimol; Mutation; Polymerase Chain Reaction; Rats; Receptors, LHRH; RNA, Messenger; Tissue Distribution | 1995 |
Correlation between in vitro and in vivo models of proconvulsive activity with the carbapenem antibiotics, biapenem, imipenem/cilastatin and meropenem.
Topics: Analysis of Variance; Animals; Binding, Competitive; Cilastatin; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Imipenem; Injections, Intravenous; Male; Meropenem; Mice; Muscimol; Pentylenetetrazole; Rats; Receptors, GABA-A; Seizures; Thienamycins | 1995 |
Inactivity of phosphoethanolamine, an endogenous GABA analog decreased in Alzheimer's disease, at GABA binding sites.
Topics: Alzheimer Disease; Animals; Ethanolamines; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Pyridazines; Rats; Rats, Inbred F344; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Tritium | 1995 |
Noradrenergic enhancement of GABA-induced input resistance changes in layer V regular spiking pyramidal neurons of rat somatosensory cortex.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colforsin; Electrophysiology; gamma-Aminobutyric Acid; In Vitro Techniques; Isoproterenol; Membrane Potentials; Microelectrodes; Muscimol; Norepinephrine; Pyramidal Cells; Rats; Somatosensory Cortex | 1995 |
Short applications of gamma-aminobutyric acid increase intracellular calcium concentrations in single identified rat lactotrophs.
Topics: Animals; Calcium; Calcium Channel Blockers; Carnosine; Clonazepam; Female; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Immunohistochemistry; Ion Channel Gating; Membrane Potentials; Muscimol; Patch-Clamp Techniques; Pituitary Gland, Anterior; Radioimmunoassay; Rats; Rats, Wistar; Receptors, GABA-A | 1994 |
Trichloroethanol potentiation of gamma-aminobutyric acid-activated chloride current in mouse hippocampal neurones.
Topics: Animals; Cells, Cultured; Chloride Channels; Drug Synergism; Ethanol; Ethylene Chlorohydrin; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Mice; Muscimol; Neurons; Patch-Clamp Techniques; Pentobarbital; Receptors, GABA-A; Up-Regulation | 1994 |
Effect of gamma-aminobutyric acid on synaptic transmission and long-term potentiation in rat superior cervical ganglion.
Topics: Action Potentials; Animals; Baclofen; Electric Stimulation; gamma-Aminobutyric Acid; Ganglia, Sympathetic; Long-Term Potentiation; Male; Muscimol; Rats; Rats, Wistar; Receptors, Nicotinic; Synaptic Transmission | 1994 |
GABAergic system inducing hyperthermia in the rat preoptic area: its independence of prostaglandin E2 system.
Topics: Analysis of Variance; Animals; Bicuculline; Body Temperature; Dinoprostone; Dose-Response Relationship, Drug; Fever; gamma-Aminobutyric Acid; Haloperidol; Male; Microdialysis; Muscimol; Perfusion; Preoptic Area; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetrodotoxin; Time Factors | 1994 |
Attenuation of a voltage-dependent sodium current by GABA (identified neurons, buccal ganglia, Helix pomatia).
Topics: Animals; Baclofen; Cobalt; gamma-Aminobutyric Acid; Ganglia, Invertebrate; Helix, Snails; In Vitro Techniques; Membrane Potentials; Muscimol; Neurons; Patch-Clamp Techniques; Sodium Channels | 1994 |
Homomeric rho 1 GABA channels: activation properties and domains.
Topics: Amino Acid Sequence; Animals; Base Sequence; Chloride Channels; Crotonates; Eye Proteins; Female; gamma-Aminobutyric Acid; Humans; Membrane Potentials; Microinjections; Molecular Sequence Data; Muscimol; Mutagenesis, Site-Directed; Oocytes; Protein Conformation; Receptors, GABA-A; Recombinant Fusion Proteins; Retina; RNA, Complementary; Sequence Alignment; Sequence Homology, Amino Acid; Xenopus laevis | 1994 |
GABAergic and dopaminergic systems may be involved in seizures induced by pyrimethamine in mice.
Topics: Animals; Bicuculline; Diazepam; Dopamine; Drug Interactions; gamma-Aminobutyric Acid; Levodopa; Mice; Mice, Inbred Strains; Muscimol; Phenobarbital; Pyrimethamine; Seizures | 1994 |
Drosophila GABA-gated chloride channel: modified [3H]EBOB binding site associated with Ala-->Ser or Gly mutants of Rdl subunit.
Topics: Alanine; Animals; Binding Sites; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Drosophila melanogaster; Drosophila Proteins; gamma-Aminobutyric Acid; Glycine; Insecticide Resistance; Ion Channel Gating; Muscimol; Mutation; Receptors, GABA-A; Serine; Structure-Activity Relationship; Tritium | 1995 |
Combination therapy protects ischemic brain in rats. A glutamate antagonist plus a gamma-aminobutyric acid agonist.
Topics: Animals; Brain; Brain Ischemia; Cerebral Infarction; Dizocilpine Maleate; Drug Combinations; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Learning; Male; Microspheres; Motor Activity; Muscimol; Organ Size; Rats; Rats, Sprague-Dawley; Reaction Time | 1994 |
NMDA-GABA interactions in an animal model of behaviour: a gating mechanism from motivation toward psychotic-like symptoms.
Topics: Alprazolam; Animals; Behavior, Animal; Desipramine; Disease Models, Animal; Dizocilpine Maleate; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Motivation; Motor Activity; Muscimol; N-Methylaspartate; Pentylenetetrazole; Psychotic Disorders; Rats; Rats, Wistar; Swimming | 1994 |
Heterogeneity of GABAA receptor in goldfish retina.
Topics: Affinity Labels; Animals; Antibodies, Monoclonal; Autoradiography; Cattle; Flunitrazepam; gamma-Aminobutyric Acid; Goldfish; Immunoblotting; Immunohistochemistry; Indicators and Reagents; Molecular Weight; Muscimol; Receptors, GABA-A; Retina; Synaptic Membranes; Synaptic Transmission | 1994 |
Age-related changes of GABA-activated chloride channel properties in brain cortex synaptic plasma membrane: evidence for phospholipase involvement.
Topics: Aging; Animals; Arachidonic Acid; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chloride Channels; Chlorides; Convulsants; Diglycerides; gamma-Aminobutyric Acid; Kinetics; Muscimol; Phospholipases; Picrotoxin; Rats; Rats, Wistar; Sulfur Radioisotopes; Synaptic Membranes; Synaptosomes | 1994 |
A GABAergic mechanism in the medial septum influences cortical arousal and locomotor activity but not a previously learned spatial discrimination task.
Topics: Animals; Arousal; Brain; Cerebral Cortex; Discrimination, Psychological; Electroencephalography; Electromyography; gamma-Aminobutyric Acid; Male; Microdialysis; Motor Activity; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A; Sleep, REM; Space Perception | 1994 |
A novel gamma-aminobutyric acid receptor subunit (rho 2) cloned from human retina forms bicuculline-insensitive homooligomeric receptors in Xenopus oocytes.
Topics: Animals; Bicuculline; Chemical Phenomena; Chemistry; Chloride Channels; Cloning, Molecular; Dose-Response Relationship, Drug; Electrophysiology; Female; gamma-Aminobutyric Acid; Humans; Muscimol; Oocytes; Picrotoxin; Receptors, GABA; Retina; Xenopus | 1994 |
Molecular pharmacology of gamma-aminobutyric acid type A receptor agonists and partial agonists in oocytes injected with different alpha, beta, and gamma receptor subunit combinations.
Topics: Animals; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Humans; Isoxazoles; Muscimol; Oocytes; Oxazolidinones; Piperidines; Receptors, GABA-A; Recombinant Proteins; Structure-Activity Relationship; Xenopus | 1994 |
Effect of gamma-aminobutyric acid modulation on neuronal ischemia in rabbits.
Topics: Animals; Bicuculline; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Injections, Intravenous; Ischemia; Muscimol; Rabbits; Spinal Cord | 1994 |
Developmental loss of GABA- and glycine-induced depolarization and Ca2+ transients in embryonic rat dorsal horn neurons in culture.
Topics: Animals; Bicuculline; Calcium Channel Agonists; Calcium Channels; Cells, Cultured; gamma-Aminobutyric Acid; Glycine; Ion Channel Gating; Membrane Potentials; Muscimol; Neuromuscular Depolarizing Agents; Neurons; Patch-Clamp Techniques; Rats; Spinal Cord | 1994 |
Glycine and GABAA antagonists reduce the inhibition of primate spinothalamic tract neurons produced by stimulation in periaqueductal gray.
Topics: Animals; Bicuculline; Brain Mapping; Dose-Response Relationship, Drug; Electric Stimulation; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glycine; Hot Temperature; Macaca fascicularis; Male; Muscimol; Neurons; Pain; Periaqueductal Gray; Physical Stimulation; Spinal Cord; Strychnine; Thalamus | 1994 |
GABA uptake into isolated retinal Müller glial cells of the guinea-pig detected electrophysiologically.
Topics: Animals; Baclofen; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Muscimol; Neuroglia; Retina | 1994 |
Perfusion of the preoptic area with muscimol or prostaglandin E2 stimulates cardiovascular function in anesthetized rats.
Topics: Adrenal Medulla; Adrenalectomy; Animals; Blood Pressure; Dinoprostone; Foot; gamma-Aminobutyric Acid; Heart Rate; Hemodynamics; Male; Microdialysis; Muscimol; Norepinephrine; Perfusion; Preoptic Area; Propranolol; Rats; Rats, Wistar; Regional Blood Flow; Stimulation, Chemical; Sympathetic Nervous System | 1994 |
Cloning and functional expression of a Drosophila gamma-aminobutyric acid receptor.
Topics: Amino Acid Sequence; Animals; Base Sequence; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cloning, Molecular; Convulsants; DNA Primers; DNA, Complementary; Drosophila melanogaster; Female; Flunitrazepam; gamma-Aminobutyric Acid; Gene Expression; Macromolecular Substances; Molecular Sequence Data; Muscimol; Oocytes; Pentobarbital; Picrotoxin; Polymerase Chain Reaction; Receptors, GABA; Receptors, GABA-A; Transcription, Genetic; Xenopus laevis | 1994 |
Biphasic gabaergic regulation of GnRH secretion in GT1 cell lines.
Topics: Animals; Baclofen; Cell Line; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Mice; Mice, Transgenic; Muscimol; Neurons; Receptors, GABA | 1994 |
[N-methyl-3H]methylphenazepam--a new ligand for benzodiazepine receptors].
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Corpus Striatum; Diazepam; gamma-Aminobutyric Acid; Male; Muscimol; Radioligand Assay; Rats; Receptors, GABA-A; Synaptic Membranes; Tritium | 1993 |
Kindling induces time-dependent and regional specific changes in the [3H]muscimol binding in the rat hippocampus: a quantitative autoradiographic study.
Topics: Allosteric Site; Animals; Autoradiography; Electric Stimulation; gamma-Aminobutyric Acid; Hippocampus; Image Processing, Computer-Assisted; Kindling, Neurologic; Male; Models, Biological; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A; Seizures | 1994 |
Interactions between laudanosine, GABA, and opioid subtype receptors: implication for laudanosine seizure activity.
Topics: Animals; Bicuculline; Binding, Competitive; Brain; Cell Membrane; Cerebral Ventricles; GABA Antagonists; gamma-Aminobutyric Acid; Injections, Intraventricular; Injections, Spinal; Isoquinolines; Kinetics; Male; Mice; Mice, Inbred Strains; Muscimol; Narcotic Antagonists; Pain; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Seizures; Spinal Cord; Substance Withdrawal Syndrome | 1994 |
Sexual differences in the effect of the GABAergic system on LH secretion and in the hypothalamic ontogenesis of GABAA receptors in prepubertal rats.
Topics: Aging; Aminooxyacetic Acid; Animals; Female; gamma-Aminobutyric Acid; Hypothalamus; Luteinizing Hormone; Male; Muscimol; Orchiectomy; Organ Specificity; Rats; Rats, Wistar; Receptors, GABA-A; Sex Characteristics; Sexual Maturation | 1994 |
GABA inhibition of somatostatin gene expression in cultured hypothalamic neurones.
Topics: Actins; Animals; Bicuculline; Cell Survival; Cells, Cultured; DNA; DNA Probes; Female; gamma-Aminobutyric Acid; Gene Expression; Hypothalamus; Muscimol; Neurons; Pregnancy; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Somatostatin | 1993 |
Interactions between glutamate, GABA, acetylcholine and histamine in the periaqueductal gray's control of vocalization in the squirrel monkey.
Topics: Acetylcholine; Animals; Bicuculline; Carbachol; Diphenhydramine; Drug Interactions; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Histamine; Homocysteine; Kynurenic Acid; Muscimol; Periaqueductal Gray; Saimiri; Scopolamine; Vocalization, Animal | 1993 |
Postischemic changes in the binding of excitatory and inhibitory neurotransmitters in the gerbil brain.
Topics: Animals; Autoradiography; Brain Chemistry; Dizocilpine Maleate; gamma-Aminobutyric Acid; Gerbillinae; Glutamates; Glutamic Acid; Histocytochemistry; Ischemic Attack, Transient; Male; Muscimol; N-Methylaspartate; Neurotransmitter Agents; Receptors, GABA; Receptors, N-Methyl-D-Aspartate | 1993 |
Bidirectional modulation of GABA-gated chloride channels by divalent cations: inhibition by Ca2+ and enhancement by Mg2+.
Topics: Animals; Calcium; Calcium Channel Blockers; Cations, Divalent; Cerebral Cortex; Chloride Channels; Chlorides; gamma-Aminobutyric Acid; Ion Channel Gating; Magnesium; Male; Muscimol; Rats; Rats, Sprague-Dawley; Synaptosomes; Zinc | 1994 |
A novel GABA receptor on bipolar cell terminals in the tiger salamander retina.
Topics: Animals; Bicuculline; Chlorides; Crotonates; Electrophysiology; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Muscimol; Pentobarbital; Picrotoxin; Pyridazines; Receptors, GABA; Receptors, GABA-A; Retina; Retinal Ganglion Cells; Urodela | 1994 |
Enteric GABA-containing nerves projecting to the guinea-pig inferior mesenteric ganglion modulate acetylcholine release.
Topics: Acetylcholine; Animals; Baclofen; Bicuculline; Colon; Diazepam; Electric Stimulation; gamma-Aminobutyric Acid; Ganglia, Sympathetic; Guinea Pigs; In Vitro Techniques; Male; Mesentery; Muscimol; Neural Pathways; Receptors, GABA-A; Receptors, GABA-B; Splanchnic Nerves; Synaptic Transmission | 1993 |
Nucleus basalis magnocellularis and attention: effects of muscimol infusions.
Topics: Animals; Appetitive Behavior; Attention; Conditioning, Operant; Discrimination Learning; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Muscimol; Olivary Nucleus; Pitch Perception; Prosencephalon; Psychomotor Performance; Rats; Reaction Time; Substantia Innominata; Visual Perception | 1993 |
GABAergic nigro-collicular pathways modulate the defensive behaviour elicited by midbrain tectum stimulation.
Topics: Aggression; Animals; Bicuculline; Electric Stimulation; Escape Reaction; GABA Antagonists; gamma-Aminobutyric Acid; Kainic Acid; Male; Mesencephalon; Microinjections; Muscimol; Nerve Fibers; Neural Pathways; Rats; Rats, Wistar; Stimulation, Chemical; Substantia Nigra; Superior Colliculi | 1993 |
Acetylcholine release in the hippocampus: effects of cholinergic and GABAergic compounds in the medial septal area.
Topics: Acetylcholine; Animals; Brain; Cerebral Cortex; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Electrochemistry; Female; gamma-Aminobutyric Acid; Hippocampus; Injections; Microdialysis; Muscimol; Oxotremorine; Parasympathomimetics; Rats; Rats, Inbred F344; Scopolamine | 1994 |
GABA transporters and GABAC-like receptors on catfish cone- but not rod-driven horizontal cells.
Topics: Animals; Baclofen; Bicuculline; Carrier Proteins; Chloride Channels; Crotonates; Electrophysiology; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Ictaluridae; Kainic Acid; Kinetics; Membrane Proteins; Membrane Transport Proteins; Muscimol; Organic Anion Transporters; Picrotoxin; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Retinal Cone Photoreceptor Cells; Retinal Rod Photoreceptor Cells; Stereoisomerism; Time Factors | 1994 |
Hypothalamic GABAergic influences on treadmill exercise responses in rats.
Topics: Animals; Behavior, Animal; Blood Pressure; Body Weight; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; Hemodynamics; Hypothalamus; Hypothalamus, Posterior; Male; Muscimol; Physical Exertion; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Vascular Resistance | 1994 |
The influence of thalamic GABA transmission on the susceptibility of adult rats to flurothyl induced seizures.
Topics: Aminocaproates; Animals; Anticonvulsants; Baclofen; Behavior, Animal; Bicuculline; Flurothyl; gamma-Aminobutyric Acid; Male; Microinjections; Muscimol; Rats; Rats, Sprague-Dawley; Seizures; Synaptic Transmission; Thalamic Nuclei; Vigabatrin | 1993 |
Further evidence for a functional dorsal-ventral division of the rat striatum: GABAergic involvement in oral movements.
Topics: Animals; Apomorphine; Behavior, Animal; Benzamides; Benzazepines; Carbachol; Corpus Striatum; Dopamine; Flunitrazepam; gamma-Aminobutyric Acid; Jaw; Male; Muscimol; N-Methylscopolamine; Picrotoxin; Pilocarpine; Rats; Rats, Sprague-Dawley; Scopolamine Derivatives | 1993 |
Biphasic GABA-A receptor-mediated effect on the spontaneous activity of the circular layer in cat terminal ileum.
Topics: Animals; Atropine; Baclofen; Bicuculline; Cats; gamma-Aminobutyric Acid; Ileum; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Picrotoxin; Receptors, GABA-A; Sesterterpenes; Tetrodotoxin | 1993 |
Involvement of both GABAA and GABAB receptors in tonic inhibitory control of blood pressure at the rostral ventrolateral medulla of the rat.
Topics: Animals; Baclofen; Blood Pressure; Brain; Cardiovascular System; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Heart Rate; Male; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B | 1993 |
gamma-Aminobutyric acid-induced elevation of intracellular calcium concentration in pituitary cells of neonatal rats.
Topics: Animals; Animals, Newborn; Baclofen; Calcium; Female; Fura-2; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Nifedipine; Picrotoxin; Pituitary Gland; Potassium Chloride; Rats; Rats, Wistar; Receptors, GABA-A; Verapamil | 1993 |
GABA control of LHRH release is dependent on the steroid milieu.
Topics: Animals; Estradiol; Estrus; Feedback; Female; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Hypothalamus; Muscimol; Ovariectomy; Ovulation; Preoptic Area; Rats; Secretory Rate | 1993 |
Behavioral activation by stimulation of a GABAergic mechanism in the preoptic area of rat.
Topics: Animals; Behavior, Animal; Bicuculline; Corpus Striatum; Dialysis; Dopamine; gamma-Aminobutyric Acid; Grooming; Habituation, Psychophysiologic; Haloperidol; Male; Motor Activity; Muscimol; Preoptic Area; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tetrodotoxin | 1993 |
Reduction of GABA inhibition in Purkinje and cerebellar nuclei neurons in climbing fibre deafferented cerebella of rat.
Topics: Animals; Baclofen; Cerebellar Nuclei; Denervation; Electrophysiology; gamma-Aminobutyric Acid; Iontophoresis; Microelectrodes; Muscimol; Nerve Fibers; Neurons; Neurons, Afferent; Purkinje Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B | 1993 |
GABA alters GABAA receptor mRNAs and increases ligand binding.
Topics: Animals; Anticonvulsants; Base Sequence; Bicuculline; Cells, Cultured; Cerebellum; DNA Primers; gamma-Aminobutyric Acid; Gene Expression; Isoxazoles; Macromolecular Substances; Molecular Sequence Data; Muscimol; Neurons; Polymerase Chain Reaction; Rats; Receptors, GABA-A; RNA, Messenger | 1993 |
Pharmacological characteristics of GABAA responses in postnatal suprachiasmatic neurons in culture.
Topics: Animals; Bicuculline; Cells, Cultured; Electrophysiology; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Muscimol; Neurons; Rats; Receptors, GABA-A; Suprachiasmatic Nucleus; Zinc | 1993 |
Natural mutation of GABAA receptor alpha 6 subunit alters benzodiazepine affinity but not allosteric GABA effects.
Topics: Animals; Azides; Benzodiazepines; Binding Sites; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cerebellum; Cloning, Molecular; Convulsants; Diazepam; gamma-Aminobutyric Acid; Granulocytes; Humans; Kidney; Muscimol; Mutation; Picrotoxin; Rats; Receptors, GABA-A; Recombinant Proteins; Transfection | 1993 |
GABAergic modulation of striatal cholinergic interneurons: an in vivo microdialysis study.
Topics: Acetylcholine; Analysis of Variance; Animals; Baclofen; Bicuculline; Corpus Striatum; gamma-Aminobutyric Acid; Interneurons; Kinetics; Male; Microdialysis; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Time Factors | 1994 |
Responses of floccular Purkinje cells to sinusoidal vertical rotation and effects of muscimol infusion into the flocculus in alert cats.
Topics: Animals; Cats; Cerebellum; gamma-Aminobutyric Acid; Injections; Muscimol; Purkinje Cells; Reflex, Vestibulo-Ocular; Rotation; Saccades; Visual Pathways | 1993 |
GABAB-receptor activation alters the firing pattern of dopamine neurons in the rat substantia nigra.
Topics: Animals; Baclofen; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Evoked Potentials; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Male; Membrane Potentials; Muscimol; Neurons; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Substantia Nigra | 1993 |
Effects of GABAergic drugs on ethanol-induced gastric lesions.
Topics: Animals; Baclofen; Bicuculline; Diazepam; Ethanol; GABA Antagonists; gamma-Aminobutyric Acid; Gastrointestinal Hemorrhage; Indomethacin; Male; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, GABA; Valproic Acid | 1993 |
Role of the caudal fastigial nucleus in saccade generation. II. Effects of muscimol inactivation.
Topics: Animals; Attention; Brain Mapping; Cerebellar Nuclei; Dominance, Cerebral; gamma-Aminobutyric Acid; Macaca mulatta; Male; Muscimol; Neural Inhibition; Neural Pathways; Orientation; Pursuit, Smooth; Reaction Time; Saccades; Visual Pathways | 1993 |
Genes required for GABA function in Caenorhabditis elegans.
Topics: Animals; Behavior, Animal; Caenorhabditis elegans; Cell Differentiation; gamma-Aminobutyric Acid; Genes, Helminth; Muscimol; Mutation; Neurons; Nipecotic Acids; Proline | 1993 |
GABA induces Ca2+ transients in astrocytes.
Topics: Animals; Astrocytes; Baclofen; Bicuculline; Calcium; Cells, Cultured; Cerebral Cortex; Cytosol; gamma-Aminobutyric Acid; Immunohistochemistry; Muscimol; Nicotinic Acids; Nifedipine; Rats | 1993 |
Influence of GABA on neurons of the gustatory zone of the rat nucleus of the solitary tract.
Topics: Animals; Baclofen; Bicuculline; Brain Mapping; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Magnesium; Male; Medulla Oblongata; Membrane Potentials; Muscimol; Neurons; Perfusion; Rats; Taste; Tetrodotoxin | 1993 |
Differential effects of local inactivation within motor cortex and red nucleus on performance of an elbow task in the cat.
Topics: Animals; Cats; Forelimb; gamma-Aminobutyric Acid; Joints; Lidocaine; Microinjections; Motor Activity; Motor Cortex; Muscimol; Neurons; Red Nucleus | 1993 |
Theta-like activity in hippocampal formation slices: cholinergic-GABAergic interaction.
Topics: Animals; Atropine; Bicuculline; Carbachol; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Muscimol; Parasympathetic Nervous System; Rats; Rats, Wistar; Theta Rhythm | 1993 |
Excitatory and inhibitory responses mediated by GABAA and GABAB receptors in guinea pig distal colon.
Topics: Animals; Baclofen; Colon; Dose-Response Relationship, Drug; Drug Interactions; gamma-Aminobutyric Acid; Guinea Pigs; Male; Muscimol; Muscle Contraction; Muscle, Smooth; Nitroprusside; Receptors, GABA-A; Tetrodotoxin | 1993 |
GABA-activated chloride channels in secretory nerve endings.
Topics: Animals; Bicuculline; Chlordiazepoxide; Chloride Channels; Chlorides; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Membrane Potentials; Membrane Proteins; Muscimol; Nerve Endings; Picrotoxin; Pituitary Gland, Posterior; Rats; Receptors, GABA-A | 1993 |
The attenuation of GABA sensitivity in the maturing myelin-deficient rat optic nerve.
Topics: Action Potentials; Aging; Animals; Bicuculline; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Myelin Sheath; Nipecotic Acids; Optic Nerve; Proline; Rats; Rats, Mutant Strains; Receptors, GABA-A; Reference Values | 1993 |
Inhibition of luteinizing hormone secretion in ovariectomized ewes during the breeding season by gamma-aminobutyric acid (GABA) is mediated by GABA-A receptors, but not GABA-B receptors.
Topics: Animals; Bicuculline; Estradiol; Female; gamma-Aminobutyric Acid; Luteinizing Hormone; Muscimol; Ovariectomy; Receptors, GABA-A; Reproduction; Sheep | 1993 |
The spinal GABA system modulates burst frequency and intersegmental coordination in the lamprey: differential effects of GABAA and GABAB receptors.
Topics: Animals; Baclofen; Bicuculline; Culture Techniques; Diazepam; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Lampreys; Locomotion; Motor Neurons; Muscimol; Muscles; N-Methylaspartate; Nerve Net; Neurons; Nipecotic Acids; Proline; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Nerve Roots; Synaptic Transmission | 1993 |
GABA modulates neurotransmission in sinus node via stimulation of GABAA receptor.
Topics: Acetylcholine; Adrenergic Fibers; Animals; Bicuculline; Cholinergic Fibers; Drug Interactions; Female; gamma-Aminobutyric Acid; Guinea Pigs; Male; Muscimol; Norepinephrine; Receptors, GABA-A; Sinoatrial Node; Synaptic Transmission; Tritium | 1993 |
Spontaneous cytosolic calcium pulsing detected in Xenopus melanotrophs: modulation by secreto-inhibitory and stimulant ligands.
Topics: Animals; Baclofen; Calcium; Calcium Channel Blockers; Cells, Cultured; Cytosol; Dopamine; Female; gamma-Aminobutyric Acid; Male; Melanocyte-Stimulating Hormones; Muscimol; Neuropeptide Y; Nickel; Periodicity; Pertussis Toxin; Pituitary Gland; Receptors, GABA-A; Virulence Factors, Bordetella; Xenopus laevis | 1993 |
Intraseptal injection of GABA and benzodiazepine receptor ligands alters high-affinity choline transport in the hippocampus.
Topics: Acetylcholinesterase; Animals; Baclofen; Brain; Carbolines; Chlordiazepoxide; Choline; Convulsants; Flumazenil; gamma-Aminobutyric Acid; Hippocampus; Injections; Male; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synaptosomes | 1993 |
Involvement of GABAA receptors in the outgrowth of cultured hippocampal neurons.
Topics: Animals; Bicuculline; Cell Size; Cells, Cultured; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Muscimol; Neurites; Neurons; Rats; Rats, Wistar; Receptors, GABA-A | 1993 |
Autoreceptor-mediated regulation of GABA release: role of uptake inhibition and effects of novel GABAB antagonists.
Topics: Animals; Bicuculline; Brain; Electric Stimulation; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Nipecotic Acids; Organophosphorus Compounds; Rats; Receptors, GABA-A | 1993 |
Do benzodiazepines induce sleep by a GABAergic mechanism?
Topics: Animals; Benzodiazepines; Bicuculline; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sleep; Triazolam | 1993 |
GABAA receptor-induced inhibition of neuronal burst firing is weak in rat somatosensory cortex.
Topics: Animals; Baclofen; Flurazepam; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Neurons; Rats; Rats, Wistar; Receptors, GABA-A; Somatosensory Cortex | 1993 |
Effects of gabapentin on release of gamma-aminobutyric acid from slices of rat neostriatum.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Neostriatum; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A | 1993 |
GABAergic cells and signals appear together in the early post-mitotic period of telencephalic and striatal development.
Topics: Acridine Orange; Animals; Corpus Striatum; Female; Flow Cytometry; Fluorescent Dyes; gamma-Aminobutyric Acid; Immunohistochemistry; Intermediate Filaments; Isoxazoles; Mitosis; Muscimol; Neuromuscular Depolarizing Agents; Phenotype; Pregnancy; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium Channels; Telencephalon | 1993 |
In vivo modulation of acetylcholine in the nucleus accumbens of freely moving rats: II. Inhibition by gamma-aminobutyric acid.
Topics: Acetylcholine; Animals; Baclofen; Bicuculline; Choline; Dose-Response Relationship, Drug; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Infusions, Parenteral; Kinetics; Male; Muscimol; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Time Factors | 1993 |
GABAA receptor subtypes: ligand binding heterogeneity demonstrated by photoaffinity labeling and autoradiography.
Topics: Affinity Labels; Animals; Autoradiography; Brain; Flunitrazepam; gamma-Aminobutyric Acid; Muscimol; Rats; Receptors, GABA-A; Tissue Distribution | 1993 |
Catalepsy induced by muscimol infused into the hypothalamus can be sensitized and is modulated by ovarian steroids.
Topics: Animals; Brain Mapping; Catalepsy; Dopamine; Estradiol; Female; gamma-Aminobutyric Acid; Hypothalamic Area, Lateral; Muscimol; Ovariectomy; Ovary; Rats; Rats, Sprague-Dawley | 1993 |
Differential expression of gamma-aminobutyric acid receptors in immortalized luteinizing hormone-releasing hormone neurons.
Topics: Animals; Bicuculline; Blotting, Northern; Cell Line; DNA Probes; Drug Synergism; gamma-Aminobutyric Acid; Gene Expression; Gonadotropin-Releasing Hormone; Hypothalamus; Male; Muscimol; Neurons; Potassium; Rats; Rats, Sprague-Dawley; Receptors, GABA; RNA, Messenger | 1993 |
GABA agonist "muscimol" is neuroprotective in repetitive transient forebrain ischemia in gerbils.
Topics: Animals; Brain Ischemia; Cerebral Cortex; Corpus Striatum; gamma-Aminobutyric Acid; Gerbillinae; Hippocampus; Male; Muscimol; Substantia Nigra; Thalamus | 1993 |
Attenuation of anticonvulsant effects of diazepam after chronic treatment with bicuculline.
Topics: Animals; Anticonvulsants; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Male; Muscimol; Pentobarbital; Rats; Rats, Inbred F344; Rats, Inbred Lew; Receptors, GABA; Sleep | 1993 |
Novel GABA responses from rod-driven retinal horizontal cells.
Topics: Animals; Bicuculline; Chlorides; Crotonates; Diazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Muscimol; Pentobarbital; Perches; Photoreceptor Cells; Receptors, GABA; Retina | 1993 |
The substantia innominata complex and the peripeduncular nucleus in orofacial dyskinesia: a pharmacological and anatomical study in cats.
Topics: Animals; Behavior, Animal; Cats; Cholera Toxin; Dyskinesia, Drug-Induced; Face; gamma-Aminobutyric Acid; Histocytochemistry; Male; Mesencephalon; Mouth; Muscimol; Picrotoxin; Substantia Innominata | 1993 |
Effects of GABAmimetics on electrocorticographic spike discharges induced by guanidinoethanesulfonic acid (amidino-taurine) in the rat.
Topics: Action Potentials; Animals; Cerebral Cortex; Diazepam; Electroencephalography; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rats, Sprague-Dawley; Taurine | 1993 |
GABA-induced motility of spinal neuroblasts develops along a ventrodorsal gradient and can be mimicked by agonists of GABAA and GABAB receptors.
Topics: Age Factors; Animals; Animals, Newborn; Baclofen; Chemotaxis; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Muscimol; Neuronal Plasticity; Rats; Rats, Sprague-Dawley; Spinal Cord | 1995 |
Two types of functionally different GABAA receptors mediate GABA modulation of cholinergic transmission in cat terminal ileum.
Topics: Animals; Atropine; Bicuculline; Cats; Dose-Response Relationship, Drug; Electric Stimulation; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Neuromuscular Junction; Pirenzepine; Receptors, GABA-A; Synaptic Transmission; Tetrodotoxin | 1995 |
Context-dependent synaptic action of glycinergic and GABAergic inputs in the dorsal cochlear nucleus.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Afferent Pathways; Animals; Cochlear Nucleus; Electrophysiology; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Membrane Potentials; Mice; Mice, Inbred CBA; Muscimol; Neural Inhibition; Neurons; Quinoxalines; Synaptic Transmission; Time Factors | 1996 |
Allopregnanolone acts as an inhibitory modulator on alpha1- and alpha6-containing GABA-A receptors.
Topics: Animals; Anti-Anxiety Agents; Cell Line; Cell Membrane; Chloride Channels; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Hypothalamus; Kinetics; Membrane Potentials; Molecular Sequence Data; Muscimol; Neurons; Patch-Clamp Techniques; Pregnanolone; Pregnenolone; Rats; Receptors, GABA-A; Recombinant Proteins; Transfection | 1996 |
Biochemical evaluations of the effects of loreclezole and propofol on the GABAA receptor in rat brain.
Topics: Anesthetics; Animals; Anticonvulsants; Brain; Bridged Bicyclo Compounds, Heterocyclic; Diazepam; Flunitrazepam; GABA Modulators; gamma-Aminobutyric Acid; Hypnotics and Sedatives; In Vitro Techniques; Male; Muscimol; Pentobarbital; Pregnanediones; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sulfur Radioisotopes; Triazoles; Tritium | 1996 |
Cardiovascular neurons in cat caudal ventrolateral medulla: location and characterization of GABAergic input.
Topics: Animals; Antibody Specificity; Blood Pressure; Carbolines; Cardiovascular System; Cats; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Heart Rate; Ligands; Male; Medulla Oblongata; Microinjections; Muscimol; Neural Pathways; Neurons; Phenylethanolamine N-Methyltransferase; Picrotoxin; Tyrosine 3-Monooxygenase | 1995 |
Ketamine may modify intestinal motility by acting at GABAA-receptor complex; an in vitro study on the guinea pig intestine.
Topics: Acetylcholine; Animals; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Gastrointestinal Motility; Guinea Pigs; Ileum; In Vitro Techniques; Ketamine; Male; Muscimol; Receptors, GABA | 1995 |
Medial amygdaloid suppression of predatory attack behavior in the cat: II. Role of a GABAergic pathway from the medial to the lateral hypothalamus.
Topics: Amygdala; Animals; Autoradiography; Bicuculline; Brain Mapping; Cats; Electric Stimulation; Female; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hypothalamic Area, Lateral; Hypothalamus, Middle; Image Processing, Computer-Assisted; Immunohistochemistry; Male; Microinjections; Muscimol; Neural Pathways; Predatory Behavior; Receptors, Neurokinin-1; Stereotaxic Techniques; Substance P | 1996 |
Startle and sensorimotor correlates of ventral thalamic dopamine and GABA in rodents.
Topics: Analysis of Variance; Animals; Apomorphine; Behavior, Animal; Dopamine; gamma-Aminobutyric Acid; Muscimol; Rats; Rats, Sprague-Dawley; Reflex, Startle; Schizophrenia; Thalamus | 1995 |
Central GABAergic mechanisms are defective in salt-induced hypertension in borderline hypertensive rats.
Topics: Animals; Antihypertensive Agents; Bicuculline; Blood Pressure; Consciousness; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; Hexamethonium; Hypertension; Injections, Intraventricular; Male; Muscimol; Phenylephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Salts; Sodium, Dietary; Stress, Physiological; Vasoconstrictor Agents | 1995 |
GABAergic transmission in the nucleus accumbens is involved in the termination of ethanol self-administration in rats.
Topics: Alcohol Drinking; Alcoholism; Animals; Bicuculline; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Motivation; Muscimol; Nucleus Accumbens; Rats; Reinforcement Schedule; Self Administration; Synaptic Transmission | 1995 |
Optical imaging of intracellular chloride in living brain slices.
Topics: Animals; Animals, Newborn; Cell Membrane Permeability; Cerebellum; Cerebral Cortex; Chlorides; Dose-Response Relationship, Drug; Fluorescent Dyes; GABA Agonists; gamma-Aminobutyric Acid; Hippocampus; Microscopy, Confocal; Microscopy, Fluorescence; Muscimol; Neurons; Organ Culture Techniques; Pyramidal Cells; Quinolinium Compounds; Rats | 1995 |
Role of amino acids in salivation and the localization of their receptors in the rat salivary gland.
Topics: Animals; Bicuculline; Electric Stimulation; gamma-Aminobutyric Acid; Glutamic Acid; Male; Muscimol; Picrotoxin; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, AMPA; Receptors, GABA; Salivary Glands; Salivation; Sublingual Gland; Submandibular Gland; Superior Cervical Ganglion | 1995 |
The extragenomic action of progesterone on human spermatozoa: evidence for a ubiquitous response that is rapidly down-regulated.
Topics: Binding Sites; Calcium; Down-Regulation; gamma-Aminobutyric Acid; Genome; Humans; Image Processing, Computer-Assisted; Male; Muscimol; Progesterone; Spermatozoa; Time Factors | 1996 |
gamma-Aminobutyric acidA receptors and spinally mediated antinociception in rats.
Topics: Animals; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Muscimol; Pain Measurement; Rats; Rats, Wistar; Reaction Time; Receptors, GABA-A; Serotonin | 1996 |
GABAA receptor binding in the aging rat inferior colliculus.
Topics: Aged; Aging; Animals; Autoradiography; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Flunitrazepam; gamma-Aminobutyric Acid; Humans; Inferior Colliculi; Ligands; Muscimol; Picrotoxin; Rats; Rats, Inbred F344; Receptors, GABA-A; Tritium | 1996 |
GABAergic stimulation regulates the phenotype of hippocampal interneurons through the regulation of brain-derived neurotrophic factor.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cell Count; Cells, Cultured; gamma-Aminobutyric Acid; Hippocampus; Immunohistochemistry; In Vitro Techniques; Interneurons; Muscimol; Nerve Tissue Proteins; Rats | 1996 |
Identification and functional characterization of a dual GABA/taurine transporter in the bullfrog retinal pigment epithelium.
Topics: Animals; Carrier Proteins; Dose-Response Relationship, Drug; Epithelium; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Membrane Glycoproteins; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; Muscimol; Organic Anion Transporters; Rana catesbeiana; Retina; Taurine | 1995 |
Tests of the motor neuron model of the local pattern-generating circuits in the swimmeret system.
Topics: Animals; Astacoidea; gamma-Aminobutyric Acid; Glutamic Acid; Models, Neurological; Motor Activity; Motor Neurons; Muscimol; Picrotoxin; Sodium Chloride | 1996 |
Functional evidence for two native GABAA receptor subtypes in adult rat hippocampus and cerebellum.
Topics: Animals; Cerebellum; Diazepam; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Hippocampus; Male; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1996 |
Gabaergic transmission and tyrosine hydroxylase expression in the nigral dopaminergic neurons: an in vivo study using a reversible ischemia model of rats.
Topics: Animals; Brain Ischemia; Cell Count; Disease Models, Animal; Dopamine; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rats, Wistar; Substantia Nigra; Tyrosine 3-Monooxygenase | 1996 |
The vigilance promoting drug modafinil increases dopamine release in the rat nucleus accumbens via the involvement of a local GABAergic mechanism.
Topics: Analysis of Variance; Animals; Baclofen; Benzhydryl Compounds; Central Nervous System Stimulants; Dopamine; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Modafinil; Muscimol; Nipecotic Acids; Nucleus Accumbens; Rats; Rats, Sprague-Dawley | 1996 |
The neurochemical pathology of thiamine deficiency: GABAA and glutamateNMDA receptor binding sites in a goat model.
Topics: Alcoholism; Amprolium; Animals; Brain Chemistry; Diazepam; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Flunitrazepam; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Goats; In Vitro Techniques; Male; Muscimol; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synaptic Membranes; Synaptosomes; Thiamine Deficiency | 1996 |
Excitatory GABA responses in embryonic and neonatal cortical slices demonstrated by gramicidin perforated-patch recordings and calcium imaging.
Topics: Animals; Animals, Newborn; Calcium; Cerebral Cortex; gamma-Aminobutyric Acid; Gramicidin; Muscimol; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, GABA; Time Factors | 1996 |
GABAergic inhibitory inputs to subfornical organ neurons in rat slice preparations.
Topics: Animals; Baclofen; Bicuculline; Evoked Potentials; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Neural Inhibition; Neural Pathways; Neurons; Organ Culture Techniques; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Subfornical Organ | 1995 |
The enhancement of muscimol-stimulated 36C1 influx by the antispastic 5-aryl-3-(alkylsulfonyl)-4H-1,2,4-triazole (MDL 27,531) in rat brain membrane vesicles.
Topics: Animals; Brain Chemistry; Chloride Channels; Chlorine; Flunitrazepam; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Ion Channel Gating; Male; Membranes; Muscimol; Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Triazoles | 1995 |
Characterization of the GABA response on identified dialysed Lymnaea neurons.
Topics: Animals; Axons; Calcium Channels; Chloride Channels; GABA Agonists; gamma-Aminobutyric Acid; Ganglia, Invertebrate; In Vitro Techniques; Lymnaea; Membrane Potentials; Muscimol; Neurons; Patch-Clamp Techniques; Receptors, GABA | 1996 |
Influence of GABAergic mechanisms on baroreceptor inputs to nucleus tractus solitarii of rats.
Topics: Afferent Pathways; Animals; Baclofen; Electrophysiology; GABA Agonists; gamma-Aminobutyric Acid; Male; Muscimol; Neurons; Pressoreceptors; Rats; Rats, Wistar; Solitary Nucleus | 1996 |
Inhibition of calcium spikes by gamma-amino-butyric acid in the neurons of Lymnaea stagnalis L.
Topics: Action Potentials; Animals; Baclofen; Calcium; GABA Agonists; gamma-Aminobutyric Acid; Ion Transport; Lymnaea; Muscimol; Neurons; Pentylenetetrazole; Pertussis Toxin; Receptors, GABA-B; Virulence Factors, Bordetella | 1995 |
Signaling pathway downstream of GABAA receptor in the growth cone.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Axons; Binding Sites; Calcium; Chlorides; Diazepam; Fetus; gamma-Aminobutyric Acid; GTPase-Activating Proteins; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Models, Neurological; Muscimol; Myristoylated Alanine-Rich C Kinase Substrate; Neurites; Picrotoxin; Prosencephalon; Proteins; Rats; Rats, Wistar; Receptors, GABA-A; Signal Transduction; Verapamil | 1996 |
Docosahexaenoic acid reduces GABA response in substantia nigra neuron of rat.
Topics: Animals; Bicuculline; Docosahexaenoic Acids; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Muscimol; Rats; Rats, Sprague-Dawley; Substantia Nigra | 1996 |
Effects of spinal cord stimulation on touch-evoked allodynia involve GABAergic mechanisms. An experimental study in the mononeuropathic rat.
Topics: Animals; Baclofen; Electric Stimulation; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Injections, Spinal; Male; Muscimol; Pain; Peripheral Nervous System Diseases; Physical Stimulation; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spinal Cord | 1996 |
Behavioral effects of 3 alpha-androstanediol. II: Hypothalamic and preoptic area actions via a GABAergic mechanism.
Topics: Androstane-3,17-diol; Animals; Estradiol; Female; GABA Agonists; gamma-Aminobutyric Acid; Hypothalamus, Middle; Kinetics; Muscimol; Posture; Preoptic Area; Progesterone; Rats; Sexual Behavior, Animal | 1996 |
Adenosine by activating A1 receptors prevents GABAA-mediated actions during hypoxia in the rat hippocampus.
Topics: Adenosine; Animals; Cell Hypoxia; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Muscimol; Phosphinic Acids; Propanolamines; Pyramidal Cells; Rats; Receptors, GABA-A; Receptors, Purinergic P1; Synaptic Transmission; Xanthines | 1996 |
Effects of gamma-aminobutyric acid (GABA) agonists and GABA uptake inhibitors on pharmacosensitive and pharmacoresistant epileptiform activity in vitro.
Topics: Animals; Baclofen; Dose-Response Relationship, Drug; Entorhinal Cortex; Epilepsy; Female; GABA Agonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Magnesium; Male; Membrane Potentials; Muscimol; Neurons; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Proline; Rats; Rats, Wistar; Tiagabine | 1996 |
Intra-amygdala muscimol decreases operant ethanol self-administration in dependent rats.
Topics: Alcoholism; Amygdala; Animals; Brain Mapping; Conditioning, Operant; gamma-Aminobutyric Acid; Male; Motivation; Muscimol; Neural Pathways; Rats; Rats, Wistar; Self Administration | 1996 |
The amygdala modulates memory for changes in reward magnitude: involvement of the amygdaloid GABAergic system.
Topics: Amygdala; Animals; Bicuculline; Dose-Response Relationship, Drug; Food Deprivation; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Memory; Muscimol; Rats; Rats, Sprague-Dawley; Reward | 1996 |
Effects of gamma-aminobutyric acid agonists on the isolated perfused rat kidney.
Topics: Animals; Baclofen; Bicuculline; GABA-A Receptor Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Kidney; Male; Muscimol; Perfusion; Rats; Rats, Wistar | 1996 |
Effects of GABA and glycine receptor antagonists on the activity and PAG-induced inhibition of rat dorsal horn neurons.
Topics: Analysis of Variance; Animals; Baclofen; Bicuculline; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glycine; Microdialysis; Muscimol; Neurons; Periaqueductal Gray; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Skin; Spinal Cord; Strychnine; Time Factors | 1996 |
Age-related modifications on the GABAA receptor binding properties from Wistar rat prefrontal cortex.
Topics: Aging; Animals; Benzodiazepines; Binding Sites; Flunitrazepam; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Male; Muscimol; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, GABA-A | 1996 |
Receptor binding sites and uptake activities mediating GABA neurotransmission in chronic alcoholics with Wernicke encephalopathy.
Topics: Adult; Aged; Aged, 80 and over; Alcoholism; Binding Sites; Diazepam; Female; Fibrosis; Flunitrazepam; Frontal Lobe; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Motor Cortex; Muscimol; Receptors, GABA; Synaptic Transmission; Wernicke Encephalopathy | 1996 |
Is upregulation of benzodiazepine receptors a compensatory reaction to reduced GABAergic tone in the brain of stressed mice?
Topics: Animals; Brain; Chlorides; Flunitrazepam; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Receptors, GABA-A; Stress, Physiological; Thiopental; Up-Regulation | 1996 |
Effect of dorsal raphe injections of the GABAA agonist, muscimol, on ethanol intake and measures of intoxication in Wistar rats.
Topics: Alcohol Drinking; Alcoholic Intoxication; Animals; Conditioning, Operant; Drinking Behavior; Ethanol; GABA Agonists; gamma-Aminobutyric Acid; Hypothermia; Injections; Male; Muscimol; Raphe Nuclei; Rats; Rats, Wistar | 1994 |
GABAergic modulation of optic nerve-evoked field potentials in the rat suprachiasmatic nucleus.
Topics: Animals; Baclofen; Bicuculline; Evoked Potentials; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Optic Nerve; Rats; Rats, Sprague-Dawley; Suprachiasmatic Nucleus | 1995 |
GABA release in posterior hypothalamus across sleep-wake cycle.
Topics: Animals; Cats; GABA Agonists; gamma-Aminobutyric Acid; Hypothalamus, Posterior; Microdialysis; Muscimol; Sleep Stages; Wakefulness | 1996 |
Inhibition of GABA-gated chloride channels in brain by the arachidonic acid metabolite, thromboxane A2.
Topics: Animals; Autoradiography; Brain; Brain Chemistry; Cerebrovascular Circulation; Chloride Channels; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Ion Channel Gating; Male; Muscimol; Rats; Rats, Sprague-Dawley; Synaptosomes; Thromboxane A2 | 1996 |
Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit.
Topics: Amino Acid Sequence; Anesthetics, Intravenous; Animals; Bicuculline; Brain; Cell Line; Consensus Sequence; DNA, Complementary; Flumazenil; Flunitrazepam; GABA Agents; gamma-Aminobutyric Acid; Humans; Molecular Sequence Data; Muscimol; Pentobarbital; Picrotoxin; Pregnanolone; Propofol; Rats; Receptors, GABA-A; Recombinant Proteins; RNA, Messenger; Transfection | 1997 |
GABAA receptor-mediated K(+)-evoked GABA release from globus pallidus--analysis using microdialysis.
Topics: Animals; Baclofen; Dinucleoside Phosphates; GABA Agonists; gamma-Aminobutyric Acid; Globus Pallidus; Male; Microdialysis; Muscimol; Nipecotic Acids; Potassium Chloride; Proline; Rats; Rats, Wistar; Receptors, GABA-A | 1997 |
Gonadotropin releasing hormone modulates gamma-aminobutyric acid-evoked intracellular calcium increase in immortalized hypothalamic gonadotropin releasing hormone neurons.
Topics: Animals; Antineoplastic Agents, Hormonal; Buserelin; Calcium; Calcium Channels; Cell Line; Fura-2; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Homeostasis; Hypothalamus; Indicators and Reagents; Muscimol; Neurons; Rats; Receptors, GABA-A; Receptors, GABA-B | 1997 |
Both GABAA and GABAB receptors participate in suppression of [CA2+]i pulsing in toad melanotrophs.
Topics: Animals; Baclofen; Calcium; Cells, Cultured; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Kinetics; Male; Muscimol; Pertussis Toxin; Pituitary Gland; Receptors, GABA-A; Receptors, GABA-B; Virulence Factors, Bordetella; Xenopus laevis | 1997 |
Daily variations in GABA receptor function in Syrian hamster cerebral cortex.
Topics: Animals; Cerebral Cortex; Chloride Channels; Circadian Rhythm; Cricetinae; Flunitrazepam; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Kinetics; Male; Mesocricetus; Muscimol; Receptors, GABA-A | 1995 |
Excitatory and trophic action of GABA and related substances in newborn mice and organotypic cerebellar culture.
Topics: Aging; Animals; Animals, Newborn; Bicuculline; Calcium; Cell Count; Cerebellum; Diazepam; GABA Agents; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Intracellular Membranes; Mice; Mice, Inbred ICR; Motor Activity; Muscimol; Organ Culture Techniques; Purkinje Cells | 1997 |
Two types of identified ascending interneurons with distinct GABA receptors in the crayfish terminal abdominal ganglion.
Topics: Animals; Astacoidea; Bicuculline; Chlorides; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Invertebrate; In Vitro Techniques; Interneurons; Male; Muscimol; Muscles; Picrotoxin; Receptors, GABA | 1997 |
Anticonvulsive activity of a new GABA mimetic drug.
Topics: Analgesics; Animals; Anticonvulsants; Behavior, Animal; Bicuculline; Catalepsy; Convulsants; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Mice; Motor Activity; Muscimol; Oxazines; Psychomotor Performance | 1997 |
Duality of glutamatergic and GABAergic control of pulsatile GnRH secretion by rat hypothalamic explants: I. Effects of antisense oligodeoxynucleotides using explants including or excluding the preoptic area.
Topics: Animals; Base Sequence; gamma-Aminobutyric Acid; Glutamic Acid; Gonadotropin-Releasing Hormone; Hypothalamus; Male; Molecular Sequence Data; Muscimol; N-Methylaspartate; Oligonucleotides, Antisense; Periodicity; Preoptic Area; Rats; Receptors, GABA; Receptors, N-Methyl-D-Aspartate | 1997 |
Duality of glutamatergic and GABAergic control of pulsatile GnRH secretion by rat hypothalamic explants: II. Reduced NR2C- and GABAA-receptor-mediated inhibition at initiation of sexual maturation.
Topics: Animals; Bicuculline; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Gonadotropin-Releasing Hormone; Hypothalamus; Kynurenic Acid; Male; Muscimol; Oligonucleotides, Antisense; Periodicity; Rats; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Sexual Maturation | 1997 |
In vitro capacitating effect of gamma-aminobutyric acid in ram spermatozoa.
Topics: Acrosome; Analysis of Variance; Animals; Baclofen; Calcimycin; Chlortetracycline; Dose-Response Relationship, Drug; Exocytosis; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Neuroprotective Agents; Pregnanolone; Prostate-Specific Antigen; Receptors, GABA-A; Receptors, GABA-B; Sheep; Sperm Capacitation; Spermatozoa | 1997 |
Shifts of cortical d.c. potential induced by application of gamma-aminobutyric acid in rats in vivo.
Topics: Animals; Cerebral Cortex; Electrophysiology; GABA Agonists; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Male; Muscimol; Rats; Rats, Sprague-Dawley | 1997 |
Neuronal regulation of astrocyte morphology in vitro is mediated by GABAergic signaling.
Topics: Animals; Animals, Newborn; Astrocytes; Baclofen; Bicuculline; Cell Adhesion; Cells, Cultured; Coculture Techniques; GABA Agonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Isoxazoles; Muscimol; Neurons; Rats; Rats, Wistar; Signal Transduction; Sodium Channel Blockers; Tetrodotoxin; Time Factors | 1997 |
Differential effects of neuroactive steroids on somatostatin and dopamine secretion from primary hypothalamic cell cultures.
Topics: Animals; Bicuculline; Cells, Cultured; Dehydroepiandrosterone Sulfate; Dopamine; Drug Synergism; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus; Muscimol; Pregnanolone; Pregnenolone; Rats; Somatostatin | 1997 |
GABA in the nucleus accumbens shell participates in the central regulation of feeding behavior.
Topics: Animals; Baclofen; Eating; Enzyme Inhibitors; Feeding Behavior; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Microinjections; Muscimol; Nipecotic Acids; Nucleus Accumbens; Proline; Rats; Rats, Sprague-Dawley; Vigabatrin | 1997 |
GABA(A) receptor activation triggers a Cl- conductance increase and a K+ channel blockade in cerebellar granule cells.
Topics: Animals; Barium; Bicuculline; Cells, Cultured; Cerebellum; Chloride Channels; Chlorides; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Mice; Mice, Inbred Strains; Muscimol; Neurons; Patch-Clamp Techniques; Picrotoxin; Potassium Channel Blockers; Receptors, GABA-A; Time Factors | 1997 |
Effects of gamma-aminobutyric acid on human sperm motility and hyperactivation.
Topics: Baclofen; Bicuculline; Cyclic AMP; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Male; Muscimol; Progesterone; Semen; Sperm Motility | 1996 |
Furosemide-sensitive calcium rise induced by GABAA-receptor stimulation in cultures of embryonic rat striatal neurons.
Topics: Animals; Bicuculline; Calcium; Corpus Striatum; Furosemide; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Neurons; Nicardipine; Rats; Receptors, GABA-A | 1997 |
GABA release in the dorsal raphe nucleus: role in the control of REM sleep.
Topics: Analysis of Variance; Animals; Brain Mapping; Cats; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Homeostasis; Microdialysis; Microinjections; Muscimol; Perfusion; Picrotoxin; Raphe Nuclei; Sleep; Sleep, REM; Time Factors; Wakefulness | 1997 |
Involvement of pallidal and nigral GABA mechanisms in the generation of tremulous jaw movements in rats.
Topics: Animals; Cholinesterase Inhibitors; GABA Agonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Globus Pallidus; Injections; Jaw; Male; Microinjections; Movement; Muscimol; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tacrine | 1997 |
Involvement of supraspinal GABA-ergic systems in clonidine-induced antinociception in the tail-pinch test in mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics; Animals; Baclofen; Bicuculline; Clonidine; GABA Antagonists; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Pain; Picrotoxin; Receptors, GABA; Tail | 1997 |
Effect of the pregnane-related GABA-active steroid alphaxalone on mice performance in the staircase test.
Topics: Alprazolam; Anesthetics; Animals; Anti-Inflammatory Agents; Corticosterone; Dose-Response Relationship, Drug; GABA Agonists; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred ICR; Muscimol; Pregnanediones; Pregnanes; Pregnenolone; Psychomotor Performance | 1997 |
Inhibitory effect of baclofen on GABA-induced depolarization and GABA-activated current in primary sensory neurons.
Topics: Animals; Baclofen; Electric Conductivity; Electrophysiology; Female; GABA Agonists; gamma-Aminobutyric Acid; Isonicotinic Acids; Male; Muscimol; Neurons, Afferent; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Time Factors | 1997 |
GABAergic control of the firing pattern of substantia nigra dopaminergic neurons.
Topics: Animals; Baclofen; Bicuculline; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Kinetics; Muscimol; Neurons; Rats; Receptors, GABA-A; Receptors, GABA-B; Substantia Nigra | 1998 |
Inhibitory interactions between perigeniculate GABAergic neurons.
Topics: Acetazolamide; Action Potentials; Animals; Anticonvulsants; Axons; Baclofen; Bicuculline; Calcium; Cerebral Cortex; Excitatory Postsynaptic Potentials; Female; Ferrets; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Geniculate Bodies; Glutamic Acid; Male; Muscimol; Neural Inhibition; Neurons; Organophosphorus Compounds; Picrotoxin; Receptors, GABA-A; Receptors, GABA-B; Receptors, Presynaptic; Tetrodotoxin; Thalamic Nuclei | 1997 |
The attenuation of kainate-induced neurotoxicity by chlormethiazole and its enhancement by dizocilpine, muscimol, and adenosine receptor agonists.
Topics: Adenosine; Animals; Body Temperature; Chlormethiazole; Dizocilpine Maleate; Drug Synergism; Drug Therapy, Combination; Entorhinal Cortex; Epilepsy, Tonic-Clonic; Excitatory Amino Acid Antagonists; GABA Agonists; gamma-Aminobutyric Acid; Gliosis; Hippocampus; Isoquinolines; Kainic Acid; Male; Muscimol; Neurons; Neuroprotective Agents; Neurotoxins; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Xanthines | 1997 |
Activity at the GABA transporter contributes to acute cellular swelling produced by metabolic impairment in retina.
Topics: Animals; Biological Transport; Carbon Radioisotopes; Carrier Proteins; Chick Embryo; Culture Techniques; GABA Agonists; GABA Antagonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Glycolysis; Iodoacetates; Ischemia; Isoxazoles; Membrane Proteins; Membrane Transport Proteins; Muscimol; Nipecotic Acids; Organic Anion Transporters; Oximes; Proline; Retina | 1997 |
Intrahippocampal GMP administration improves inhibitory avoidance performance through GABAergic and glutamatergic mechanisms in rats.
Topics: Animals; Avoidance Learning; Baclofen; Cyclic GMP; Dizocilpine Maleate; Functional Laterality; GABA Agonists; gamma-Aminobutyric Acid; Hippocampus; Male; Microinjections; Muscimol; Rats; Rats, Wistar; Reaction Time; Receptors, N-Methyl-D-Aspartate | 1997 |
Neurosteroid inhibition of cell death.
Topics: Alkaloids; Animals; Antimycin A; Benzylisoquinolines; Calcium; Cell Death; Cell Hypoxia; Cells, Cultured; Dehydroepiandrosterone Sulfate; Female; gamma-Aminobutyric Acid; Isoxazoles; Kidney Tubules, Proximal; Kinetics; L-Lactate Dehydrogenase; Mitochondria; Muscimol; Oxygen Consumption; Pregnanes; Rabbits; Receptors, GABA-A | 1997 |
Proenkephalin gene regulation in the paraventricular nucleus by GABA: interactions with opioid systems in a transgenic model.
Topics: Aminooxyacetic Acid; Animals; beta-Galactosidase; Cells, Cultured; Enkephalins; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Gene Expression Regulation; Humans; Hypothalamus; Mice; Mice, Transgenic; Muscimol; Naltrexone; Narcotic Antagonists; Organ Culture Techniques; Paraventricular Hypothalamic Nucleus; Protein Precursors; Recombinant Fusion Proteins; Saline Solution, Hypertonic; Stress, Physiological | 1998 |
The effect of GABAergic system activity on hyperthermia-induced seizures in rats.
Topics: Analysis of Variance; Animals; Bicuculline; Body Temperature Regulation; Electroencephalography; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hot Temperature; Male; Muscimol; Rats; Rats, Inbred Lew; Seizures; Semicarbazides | 1997 |
Is GABA involved in the development of caffeine tolerance?
Topics: 4-Aminobutyrate Transaminase; Animals; Bicuculline; Brain; Caffeine; Cerebellum; Cerebral Cortex; Corpus Striatum; Drug Tolerance; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus; Male; Medulla Oblongata; Motor Activity; Muscimol; Pons; Rats | 1998 |
Involvement of gamma-aminobutyric acid neurotransmission in phencyclidine-induced dopamine release in the medial prefrontal cortex.
Topics: Animals; Dizocilpine Maleate; Dopamine; Dopamine Uptake Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; GABA Agonists; gamma-Aminobutyric Acid; Male; Muscimol; N-Methylaspartate; Nomifensine; Phencyclidine; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1998 |
Interactions between GABAergic and serotoninergic systems with excitatory amino acid neurotransmission in the hypothalamic control of gonadotropin secretion in prepubertal female rats.
Topics: 5-Hydroxytryptophan; Animals; Bicuculline; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Female; Follicle Stimulating Hormone; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Gonadotropins; Hypothalamus; Luteinizing Hormone; Muscimol; Rats; Serotonin; Synaptic Transmission | 1998 |
Modulation of calcium by inhibitory systems in the developing auditory midbrain.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Aging; Animals; Auditory Pathways; Baclofen; Bicuculline; Brain; Calcium; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Gerbillinae; In Vitro Techniques; Inferior Colliculi; Membrane Potentials; Mesencephalon; Muscimol; Neurons; Reaction Time; Receptors, GABA-A; Receptors, GABA-B | 1998 |
Modulation of GAP-43 mRNA by GABA and glutamate in cultured cerebellar granule cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Blotting, Northern; Cells, Cultured; Cerebellum; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agonists; gamma-Aminobutyric Acid; GAP-43 Protein; Gene Expression Regulation, Developmental; Glial Fibrillary Acidic Protein; Glutamic Acid; Immunohistochemistry; In Situ Hybridization; Microtubule-Associated Proteins; Muscimol; N-Methylaspartate; Neurons; Neuroprotective Agents; Piperazines; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1998 |
Different GABA-receptor types are involved in the 5-HT-induced antinociception at the spinal level: a behavioral study.
Topics: Analgesics; Animals; Baclofen; Bicuculline; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Muscimol; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA; Serotonin; Spinal Cord | 1998 |
Networks of coactive neurons in developing layer 1.
Topics: Acetylcholine; Adrenergic alpha-Agonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cerebral Cortex; Electric Stimulation; Excitatory Amino Acid Agonists; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Muscimol; N-Methylaspartate; Neurons; Neurotransmitter Agents; Norepinephrine; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Tetrodotoxin; Time Factors | 1998 |
Muscimol-induced death of GABAergic neurons in rat brain aggregating cell cultures.
Topics: Animals; Brain; Cell Aggregation; Cell Death; Cells, Cultured; DNA Fragmentation; GABA Agonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Muscimol; Neurons; Nucleosomes; Rats; Rats, Sprague-Dawley | 1998 |
Effects of the neurosteroid dehydroepiandrosterone sulfate on medial vestibular nucleus neurons.
Topics: Animals; Baclofen; Cats; Dehydroepiandrosterone Sulfate; Electrophysiology; GABA-A Receptor Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Muscimol; Neurons; Rotation; Vestibular Nuclei | 1998 |
Astrocytes regulate developmental changes in the chloride ion gradient of embryonic rat ventral spinal cord neurons in culture.
Topics: Animals; Astrocytes; Bicuculline; Calcium; Calcium Channel Blockers; Cells, Cultured; Chloride Channels; Chlorides; Culture Media, Conditioned; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Microscopy, Video; Muscimol; Neurons; Nifedipine; Patch-Clamp Techniques; Rats; Receptors, GABA-A; Spinal Cord; Time Factors | 1998 |
Inhibition by gamma-aminobutyric acid system activation of epileptic seizures in spontaneously epileptic rats.
Topics: 4-Aminobutyrate Transaminase; Aminooxyacetic Acid; Animals; Brain; Electroencephalography; Enzyme Inhibitors; Epilepsy; Female; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Male; Muscimol; Rats | 1998 |
Modulation by GABA transmission in the substantia nigra compacta and reticulata of locomotor activity in rats exposed to high pressure.
Topics: Animals; Baclofen; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Helium; High Pressure Neurological Syndrome; Male; Motor Activity; Muscimol; Myoclonus; Nipecotic Acids; Proline; Rats; Rats, Sprague-Dawley; Receptors, GABA; Substantia Nigra; Synaptic Transmission; Time Factors; Vigabatrin | 1998 |
GABAergic inhibition of neonatal rat phrenic motoneurons.
Topics: Animals; Animals, Newborn; GABA Agonists; gamma-Aminobutyric Acid; Motor Neurons; Muscimol; Neural Inhibition; Phrenic Nerve; Rats; Rats, Sprague-Dawley; Respiration | 1998 |
Effects of GABA on neurons of the gustatory and visceral zones of the parabrachial nucleus in rats.
Topics: Animals; Bicuculline; Electric Impedance; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Neurons; Pons; Rats; Taste; Viscera | 1998 |
Role of GABA receptors in the bronchial response: studies in sensitized guinea-pigs.
Topics: Acetylcholine; Animals; Baclofen; Bicuculline; Bronchi; Electric Stimulation; GABA Agonists; gamma-Aminobutyric Acid; Guinea Pigs; Male; Muscimol; Muscle Contraction; Muscle, Smooth; Ovalbumin; Trachea | 1998 |
GABAergic input to cholinergic nucleus basalis neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Choline O-Acetyltransferase; Excitatory Postsynaptic Potentials; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Guinea Pigs; Immunohistochemistry; In Vitro Techniques; Muscimol; Neurons; Prosencephalon; Receptors, GABA-A; Receptors, GABA-B; Substantia Innominata; Synaptic Transmission | 1998 |
GABAergic effects on nucleus tractus solitarius neurons receiving gastric vagal inputs.
Topics: Animals; Animals, Newborn; Baclofen; Brain Stem; Electric Stimulation; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Muscimol; Neurons; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Solitary Nucleus; Stomach; Vagus Nerve | 1998 |
Occurrence of GABA and GABA receptors in human spermatozoa.
Topics: Bicuculline; Cell Membrane; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Isonicotinic Acids; Male; Muscimol; Receptors, GABA; Semen; Sperm Motility; Spermatozoa; Tritium | 1998 |
Cellular and synaptic modulation underlying substance P-mediated plasticity of the lamprey locomotor network.
Topics: Action Potentials; Animals; Electric Impedance; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; GABA Agonists; gamma-Aminobutyric Acid; Ganglia, Spinal; Glycine Agents; Lampreys; Muscimol; N-Methylaspartate; Neural Inhibition; Neuronal Plasticity; Neurons; Strychnine; Substance P; Swimming; Synaptic Transmission; Tetrodotoxin | 1998 |
Pharmacological evidence for GABAergic and glutamatergic involvement in the convulsant and behavioral effects of glutaric acid.
Topics: Animals; Behavior, Animal; Convulsants; Corpus Striatum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Agonists; gamma-Aminobutyric Acid; Glutamates; Glutarates; Injections; Male; Muscimol; Quinoxalines; Rats; Rats, Wistar; Seizures; Stereotyped Behavior | 1998 |
Functional GABA(A) receptors on human glioma cells.
Topics: Anti-Bacterial Agents; Calcium; Calcium Channel Blockers; Flunitrazepam; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Glioblastoma; Gramicidin; Humans; Membrane Potentials; Muscimol; Oligodendroglioma; Patch-Clamp Techniques; Picrotoxin; Potassium; Receptors, GABA-A; Tumor Cells, Cultured; Verapamil | 1998 |
Persistent depolarizing action of GABA in rat Cajal-Retzius cells.
Topics: Animals; Animals, Newborn; Calcium; Electrophysiology; Female; GABA Agonists; gamma-Aminobutyric Acid; Hippocampus; Membrane Potentials; Muscimol; Patch-Clamp Techniques; Potassium Channels; Pregnancy; Rats; Receptors, Bradykinin; Receptors, GABA-A | 1998 |
Inhibitors of gamma-aminobutyric acid transport as experimental tools and therapeutic agents.
Topics: Animals; Brain; Carrier Proteins; Cloning, Molecular; Drug Design; GABA Antagonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Membrane Proteins; Membrane Transport Proteins; Molecular Structure; Muscimol; Neuroglia; Neurons; Nipecotic Acids; Organic Anion Transporters; Proline; Radioligand Assay; Recombinant Proteins; Tritium | 1998 |
Defining affinity with the GABAA receptor.
Topics: Animals; Animals, Newborn; beta-Alanine; Cells, Cultured; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Hippocampus; Isoxazoles; Ligands; Muscimol; Neurons; Patch-Clamp Techniques; Pyridazines; Rats; Receptors, GABA-A | 1998 |
Mediodorsal thalamus plays a critical role in the development of limbic motor seizures.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Bicuculline; Brain Mapping; Carbon Radioisotopes; Deoxyglucose; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Limbic System; Male; Muscimol; Quinoxalines; Rats; Rats, Sprague-Dawley; Seizures; Thalamus; Time Factors; Vigabatrin | 1998 |
GABAergic neuron-to-astrocyte signaling regulates dendritic branching in coculture.
Topics: Animals; Astrocytes; Bicuculline; Cell Communication; Coculture Techniques; Dendrites; GABA Agents; gamma-Aminobutyric Acid; Immunohistochemistry; Muscimol; Neurons; Neurotransmitter Agents; Olfactory Bulb; Rats; Rats, Wistar; Tetrodotoxin | 1998 |
Decreased benzodiazepine binding with little effect on gamma-aminobutyric acid binding in rat brain after treatment with antisense oligodeoxynucleotide to the gamma-aminobutyric acidA receptor gamma-2 subunit.
Topics: Animals; Base Sequence; Benzodiazepines; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Cerebellum; Flunitrazepam; gamma-Aminobutyric Acid; Male; Muscimol; Oligonucleotides, Antisense; Protein Binding; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Tritium; Xanthines | 1998 |
GABA(A) receptor modulates the activity of inner hair cell afferents in guinea pig cochlea.
Topics: Acetylcholine; Action Potentials; Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Auditory Pathways; Baclofen; Bicuculline; Cochlea; Electrophysiology; gamma-Aminobutyric Acid; Glutamic Acid; Guinea Pigs; Hair Cells, Auditory, Inner; Iontophoresis; Muscimol; N-Methylaspartate; Receptors, GABA-A | 1998 |
Receptor subtype specific effects of GABA agonists on neurons receiving aortic depressor nerve inputs within the nucleus of the solitary tract.
Topics: Animals; Aorta; Autonomic Nervous System; Baclofen; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Iontophoresis; Male; Membrane Potentials; Muscimol; Neurons; Pressoreceptors; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Solitary Nucleus; Synapses; Synaptic Transmission | 1998 |
Synaptic inhibition in the isolated respiratory network of neonatal rats.
Topics: Action Potentials; Animals; Animals, Newborn; Anti-Bacterial Agents; Baclofen; Bicarbonates; Bicuculline; Carbon Dioxide; Chloride Channel Agonists; Chloride Channels; Chlorides; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glycine Agents; Gramicidin; Medulla Oblongata; Microdialysis; Muscimol; Neural Inhibition; Neurons; Patch-Clamp Techniques; Rats; Receptors, GABA-B; Respiration; Strychnine; Synapses; Tetrodotoxin | 1998 |
Effects of GABA on acutely isolated neurons from the gustatory zone of the rat nucleus of the solitary tract.
Topics: Animals; Baclofen; Bicuculline; Cell Membrane; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Muscimol; Neurons; Patch-Clamp Techniques; Picrotoxin; Rats; Solitary Nucleus | 1998 |
Interactions between neuropeptide Y and gamma-aminobutyric acid in stimulation of feeding: a morphological and pharmacological analysis.
Topics: Animals; Drug Synergism; Eating; GABA Agonists; gamma-Aminobutyric Acid; Male; Muscimol; Neuropeptide Y; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Tissue Distribution | 1999 |
GABAA and GABAB modulations of synaptic transmission between L1-L2 locomotor network and the motoneurons in the newborn rat isolated spinal cord.
Topics: Animals; Animals, Newborn; Baclofen; GABA Agonists; gamma-Aminobutyric Acid; Locomotion; Motor Neurons; Muscimol; Oligopeptides; Organ Culture Techniques; Rats; Receptors, GABA-A; Receptors, GABA-B; Serotonin; Spinal Cord; Synaptic Transmission | 1998 |
Expression of functional GABAA receptors in isolated human insulinoma cells.
Topics: Cadmium Chloride; Calcium Channel Blockers; Calcium Channels; Female; gamma-Aminobutyric Acid; Humans; Insulin; Insulin Secretion; Insulinoma; Isradipine; Membrane Potentials; Middle Aged; Muscimol; Pancreatic Neoplasms; Patch-Clamp Techniques; Picrotoxin; Receptors, GABA-A; Tumor Cells, Cultured | 1998 |
The K+/Cl- co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation.
Topics: Animals; Blotting, Southern; Carrier Proteins; Cell Differentiation; Chlorides; Electrophysiology; GABA Agonists; gamma-Aminobutyric Acid; Gene Expression Regulation, Developmental; Guinea Pigs; Hippocampus; In Vitro Techniques; K Cl- Cotransporters; Muscimol; Potassium; Pyramidal Cells; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Symporters | 1999 |
Neurite outgrowth-regulating properties of GABA and the effect of serum on mouse spinal cord neurons in culture.
Topics: Animals; Baclofen; Cell Movement; Cell Size; Cells, Cultured; Culture Media; Dose-Response Relationship, Drug; GABA Agonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Growth Cones; Mice; Mice, Inbred BALB C; Microscopy, Phase-Contrast; Muscimol; Neurites; Spinal Cord | 1998 |
Substance P release in the dorsal horn assessed by receptor internalization: NMDA receptors counteract a tonic inhibition by GABA(B) receptors.
Topics: Animals; Baclofen; Dizocilpine Maleate; Down-Regulation; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Muscimol; Neural Inhibition; Organ Culture Techniques; Rats; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Spinal Cord; Substance P | 1999 |
Presynaptic GABAergic control of the locomotor drive in the isolated spinal cord of neonatal rats.
Topics: Animals; Animals, Newborn; Baclofen; Electrophysiology; Excitatory Amino Acid Agonists; Free Radical Scavengers; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Locomotion; Membrane Potentials; Mephenesin; Muscimol; Muscle Relaxants, Central; N-Methylaspartate; Neural Inhibition; Organophosphorus Compounds; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Serotonin; Spinal Cord; Tetrodotoxin | 1999 |
Neurosteroid modulation of the GABAA receptor in the developing guinea pig cerebral cortex.
Topics: Animals; Benzodiazepines; Binding, Competitive; Brain Chemistry; Cerebral Cortex; Female; Flunitrazepam; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Guinea Pigs; Hypnotics and Sedatives; Male; Muscimol; Organ Size; Pregnanolone; Pyridines; Radioligand Assay; Receptors, GABA-A; Tritium; Zolpidem | 1999 |
The evidence for tonic GABAergic regulation of basal L-DOPA release via activation of inhibitory GABA(A) receptors in the nucleus tractus solitarii of anesthetized rats.
Topics: Anesthesia; Animals; Bicuculline; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Levodopa; Male; Microdialysis; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A; Solitary Nucleus | 1999 |
Comparison of gamma-aminobutyric acid effects in different parts of the cat ileum.
Topics: Acetylcholinesterase; Animals; Atropine; Baclofen; Bicuculline; Cats; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Ileum; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Tetrodotoxin | 1999 |
Ambiguous respiratory neurons are modulated by GABA(A) receptor-mediated inhibition.
Topics: Animals; Bicuculline; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; Medulla Oblongata; Muscimol; Neurons; Rats; Rats, Wistar; Receptors, GABA-A; Respiratory System | 1999 |
A reexamination of the role of GABA in the mammalian suprachiasmatic nucleus.
Topics: Action Potentials; Animals; Bicuculline; Cell Membrane Permeability; Chlorides; Circadian Rhythm; Dose-Response Relationship, Drug; Electrophysiology; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Gramicidin; In Vitro Techniques; Male; Muscimol; Neurons; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Suprachiasmatic Nucleus | 1999 |
Cholinergic and GABAergic regulation of nitric oxide synthesis in the guinea pig ileum.
Topics: Animals; Baclofen; Bicuculline; Cholinergic Agonists; Cholinergic Antagonists; Citrulline; Egtazic Acid; Electric Stimulation; Female; GABA Agonists; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Isometric Contraction; Male; Mecamylamine; Muscimol; Muscle, Smooth; Myenteric Plexus; Nitric Oxide; Nitroarginine; Oxotremorine; Scopolamine; Tetrodotoxin; Tubocurarine | 1999 |
GABAergic control of rat substantia nigra dopaminergic neurons: role of globus pallidus and substantia nigra pars reticulata.
Topics: Action Potentials; Afferent Pathways; Animals; Bicuculline; Biological Clocks; Dopamine; Electric Stimulation; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Male; Muscimol; Neurons; Rats; Rats, Sprague-Dawley; Substantia Nigra | 1999 |
GABA exerts stimulatory and inhibitory influences on gonadotropin II secretion in the Atlantic croaker (Micropogonias undulatus).
Topics: Animals; Bicuculline; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Gonadotropins, Pituitary; Gonads; Male; Muscimol; Perciformes; Pituitary Gland; Reproduction; Vigabatrin | 1999 |
Gamma-aminobutyric acid and glutamic acid receptors may mediate theophylline-induced seizures in mice.
Topics: 2-Amino-5-phosphonovalerate; Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Clonidine; Dextromethorphan; Drug Interactions; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Ketamine; Mice; Muscimol; N-Methylaspartate; Picrotoxin; Receptors, GABA; Receptors, Glutamate; Seizures; Theophylline | 1999 |
Mechanism by which GABA, through its GABA(A) receptor, modulates glutamate release from rat cortical neurons in culture.
Topics: Animals; Barbiturates; Calcium; Cells, Cultured; Cerebral Cortex; Chloride Channels; Chlorides; Fluorescence; Fluorescent Dyes; gamma-Aminobutyric Acid; Glutamic Acid; Ion Transport; Isoxazoles; Membrane Potentials; Muscimol; Neurons; Potassium Chloride; Rats; Receptors, GABA-A | 1999 |
GABA(A) receptors mediate inhibition of T cell responses.
Topics: Amidines; Animals; Autocrine Communication; Bicuculline; CD3 Complex; Cell Division; Enzyme Inhibitors; Female; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Hypersensitivity, Delayed; Immunosuppression Therapy; Interleukin-2; Lymphocyte Activation; Male; Mice; Mice, Inbred NOD; Muscimol; Pentobarbital; Picrotoxin; Receptors, GABA-A; Receptors, GABA-B; Signal Transduction; T-Lymphocytes; Vigabatrin | 1999 |
Gamma-aminobutyric acid (GABA) A and B receptors mediate the stimulatory effects of GABA on the human sperm acrosome reaction: interaction with progesterone.
Topics: Acrosome; Analysis of Variance; Baclofen; Bicuculline; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Male; Muscimol; Picrotoxin; Progesterone; Prospective Studies; Receptors, GABA-A; Receptors, GABA-B | 1999 |
Acute pentylenetetrazol injection reduces rat GABAA receptor mRNA levels and GABA stimulation of benzodiazepine binding with No effect on benzodiazepine binding site density.
Topics: Animals; Autoradiography; Brain; Down-Regulation; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Male; Muscimol; Pentylenetetrazole; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; RNA, Messenger; Time Factors; Transcription, Genetic; Tritium | 1999 |
Mapping the agonist binding site of the GABAA receptor: evidence for a beta-strand.
Topics: Animals; Binding Sites; Biotin; Chromosome Mapping; Cysteine; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; GABA Agonists; gamma-Aminobutyric Acid; Humans; Indicators and Reagents; Kidney; Membrane Potentials; Models, Molecular; Molecular Sequence Data; Muscimol; Mutagenesis, Site-Directed; Oocytes; Protein Structure, Tertiary; Receptors, GABA-A; Sequence Homology, Amino Acid; Tritium; Xenopus | 1999 |
GABA induces proliferation of immature cerebellar granule cells grown in vitro.
Topics: Animals; Cell Division; Cells, Cultured; Cellular Senescence; Cerebellum; gamma-Aminobutyric Acid; Muscimol; Rats; Rats, Sprague-Dawley | 1999 |
GABAergic inhibition of nitric oxide-mediated relaxation of guinea-pig ileum.
Topics: Animals; Bicuculline; Electric Stimulation; Enzyme Inhibitors; Female; GABA Agonists; GABA-A Receptor Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Male; Muscimol; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroarginine; Tetrodotoxin | 1999 |
Regulation of limbic motor seizures by GABA and glutamate transmission in nucleus tractus solitarius.
Topics: Animals; Bicuculline; Electric Stimulation Therapy; Excitatory Amino Acid Antagonists; GABA Agonists; gamma-Aminobutyric Acid; Glutamates; Humans; Kynurenic Acid; Lidocaine; Limbic System; Male; Muscimol; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures; Solitary Nucleus; Synaptic Transmission; Vagus Nerve | 1999 |
Inhibition of GABA system involved in cyclosporine-induced convulsions.
Topics: Animals; Anticonvulsants; Bicuculline; Binding Sites; Brain; Cells, Cultured; Cerebellum; Cyclosporine; Drug Synergism; Excitatory Amino Acid Agonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Male; Mice; Mice, Inbred Strains; Muscimol; Neurons; Rats; Rats, Wistar; Seizures; Strychnine; Tacrolimus | 1999 |
Role of the conserved lysine residue in the middle of the predicted extracellular loop between M2 and M3 in the GABA(A) receptor.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Bicuculline; Binding, Competitive; Cell Line; Conserved Sequence; Female; Flumazenil; gamma-Aminobutyric Acid; Humans; Kinetics; Lysine; Muscimol; Mutagenesis, Site-Directed; Oocytes; Protein Structure, Secondary; Radioligand Assay; Rats; Receptors, GABA-A; Recombinant Proteins; Sequence Alignment; Transfection; Xenopus laevis | 1999 |
Gabaergic control of olfactory learning in young rats.
Topics: Age Factors; Animals; Avoidance Learning; Behavior, Animal; Bicuculline; Conditioning, Psychological; Electroshock; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Neuronal Plasticity; Odorants; Rats; Rats, Long-Evans; Smell | 1999 |
GABA(A) and GABA(C) receptors have contrasting effects on excitability in superior colliculus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cobalt; Electric Stimulation; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Immunohistochemistry; In Vitro Techniques; Lidocaine; Muscimol; Rats; Rats, Long-Evans; Receptors, GABA; Receptors, GABA-A; Superior Colliculi | 1999 |
GABAergic activation inhibits the hypothalamic-pituitary-ovaric axis and sexual development in the immature female rat. Associated changes in hypothalamic glutamatergic and taurinergic systems.
Topics: Aminooxyacetic Acid; Animals; Baclofen; Enzyme Inhibitors; Estradiol; Female; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Hypothalamo-Hypophyseal System; Luteinizing Hormone; Muscimol; Organ Size; Ovary; Rats; Rats, Wistar; Sexual Maturation; Taurine | 1999 |
Facilitatory effect of unilateral lesion of the ventral tegmental area on locomotor response to stimulation of the contralateral ventral tegmental area: involvement of GABAergic transmission.
Topics: Animals; Baclofen; Bicuculline; Brain Mapping; Electric Stimulation; Functional Laterality; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Male; Models, Neurological; Motor Activity; Muscimol; Rats; Rats, Wistar; Reaction Time; Receptors, GABA-A; Receptors, GABA-B; Synaptic Transmission; Ventral Tegmental Area | 1999 |
Optical imaging reveals elevated intracellular chloride in hippocampal pyramidal neurons after oxidative stress.
Topics: 2-Amino-5-phosphonovalerate; Animals; Antioxidants; Cell Membrane Permeability; Chlorides; Chromans; Deferoxamine; Extracellular Space; Fluorescent Dyes; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Hydrogen Peroxide; In Vitro Techniques; Kinetics; Microscopy, Confocal; Muscimol; Nipecotic Acids; Oxidative Stress; Pyramidal Cells; Quinolinium Compounds; Quinoxalines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tiagabine | 1999 |
GABAA receptor modulation of temperature sensitive neurons in the diagonal band of Broca in vitro.
Topics: Animals; Bicuculline; Body Temperature Regulation; Diagonal Band of Broca; Electrophysiology; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Muscimol; Neurons; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sleep; Temperature | 1999 |
Influence of fetal alcohol exposure on the GABAergic regulation of growth hormone release in postnatal rats.
Topics: Age Factors; Animals; Animals, Newborn; Bicuculline; Body Weight; Central Nervous System Depressants; Ethanol; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Growth Hormone; Male; Muscimol; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sex Factors | 1999 |
Effects of GABAergic system on naloxone-induced jumping in morphine-dependent mice.
Topics: Animals; Baclofen; Behavior, Animal; Bicuculline; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Mice; Morphine Dependence; Muscimol; Naloxone; Narcotic Antagonists; Organophosphorus Compounds; Picrotoxin; Substance Withdrawal Syndrome | 1999 |
Effects of gamma-aminobutyric acid and peripheral benzodiazepine ligands on duodenal bicarbonate secretion.
Topics: Analysis of Variance; Animals; Antineoplastic Agents; Benzodiazepines; Bicarbonates; Bicuculline; Diazepam; Duodenum; Female; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Intestinal Mucosa; Isoquinolines; Ligands; Male; Muscimol; Rats; Rats, Inbred Lew | 1999 |
Honokiol and magnolol increase the number of [3H] muscimol binding sites three-fold in rat forebrain membranes in vitro using a filtration assay, by allosterically increasing the affinities of low-affinity sites.
Topics: Allosteric Regulation; Androstanes; Animals; Azasteroids; Binding Sites; Biphenyl Compounds; Cell Membrane; Central Nervous System Depressants; Cerebellum; Diflunisal; Drugs, Chinese Herbal; Flunitrazepam; GABA Antagonists; gamma-Aminobutyric Acid; Kinetics; Lignans; Muscimol; Picrotoxin; Propofol; Prosencephalon; Rats; Receptors, GABA-A; Tritium | 1999 |
Evidence of a functional relationship between the nucleus accumbens shell and lateral hypothalamus subserving the control of feeding behavior.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electrophysiology; Feeding Behavior; Food Deprivation; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hypothalamic Area, Lateral; Injections; Male; Muscimol; Neural Inhibition; Neurons; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 1999 |
Central GABA activation and behaviors evoked by tail-pinch stress in the rat.
Topics: Animals; Behavior, Animal; Defecation; GABA Agonists; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Microinjections; Muscimol; Pain; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Stress, Psychological; Substantia Nigra; Tail | 1999 |
Increased GABAergic activity inhibits alpha-fetoprotein mRNA expression and the proliferative activity of the HepG2 human hepatocellular carcinoma cell line.
Topics: Albumins; alpha-Fetoproteins; Blotting, Northern; Carcinoma, Hepatocellular; Cell Division; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Humans; Liver Neoplasms; Muscimol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Thymidine; Transfection; Tumor Cells, Cultured | 2000 |
Neocortical hyperexcitability after GABA withdrawal in vitro.
Topics: Animals; Flunitrazepam; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Muscimol; Neocortex; Pregnanolone; Progesterone; Rats; Rats, Wistar; Seizures; Substance Withdrawal Syndrome; Synaptic Transmission | 2000 |
Actions of midazolam on GABAergic transmission in substantia gelatinosa neurons of adult rat spinal cord slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Male; Membrane Potentials; Midazolam; Muscimol; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Spinal Cord; Substantia Gelatinosa; Synaptic Transmission | 2000 |
GABAergic projection from the arcuate nucleus to the supraoptic nucleus in the rat.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Bicuculline; Electric Stimulation; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Microdialysis; Muscimol; Rats; Supraoptic Nucleus | 2000 |
GABAergic modulation of gap junction communication in slice cultures of the rat suprachiasmatic nucleus.
Topics: Animals; Bicuculline; Cell Communication; Culture Techniques; Electrophysiology; Fluorescent Dyes; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Gap Junctions; Halothane; Isoquinolines; Muscimol; Octanols; Rats; Rats, Wistar; Suprachiasmatic Nucleus; Tetrodotoxin | 2000 |
GABAA receptor mediated elevation of Ca2+ and modulation of gonadotrophin-releasing hormone action in alphaT3-1 gonadotropes.
Topics: Anesthetics; Animals; Baclofen; Bicuculline; Biological Transport; Calcium; Calcium Channel Blockers; Cells, Cultured; Chlorides; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Mice; Muscimol; Nifedipine; Picrotoxin; Pituitary Gland; Pregnanediones; Receptors, GABA-A; Receptors, GABA-B | 2000 |
gamma-Aminobutyrate, alpha-carboxy-2-nitrobenzyl ester selectively blocks inhibitory synaptic transmission in rat dentate gyrus.
Topics: Animals; Dentate Gyrus; Evoked Potentials; Excitatory Postsynaptic Potentials; GABA Agonists; gamma-Aminobutyric Acid; Glutamates; In Vitro Techniques; Male; Muscimol; Phenylacetates; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synapses; Synaptic Transmission | 2000 |
Bilateral blockade of NMDA receptors in anterior thalamus by dizocilpine (MK-801) injures pyramidal neurons in rat retrosplenial cortex.
Topics: Animals; Anterior Thalamic Nuclei; Baclofen; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Gyrus Cinguli; HSP70 Heat-Shock Proteins; Muscimol; Nerve Degeneration; Neural Pathways; Phytohemagglutinins; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Schizophrenia | 2000 |
Nicotine reverses GABAergic inhibition of long-term potentiation induction in the hippocampal CA1 region.
Topics: Aconitine; Animals; Bridged Bicyclo Compounds, Heterocyclic; Electric Stimulation; Excitatory Postsynaptic Potentials; GABA Agonists; gamma-Aminobutyric Acid; Hippocampus; Insecticides; Interneurons; Long-Term Potentiation; Muscimol; Neural Pathways; Nicotine; Nicotinic Agonists; Pyramidal Cells; Pyridines; Rats; Receptors, GABA-A; Receptors, Nicotinic | 2000 |
GABA(A) receptors on calbindin-immunoreactive myenteric neurons of guinea pig intestine.
Topics: Animals; Calbindins; Cells, Cultured; Diazepam; Dose-Response Relationship, Drug; GABA Agonists; GABA Modulators; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Guinea Pigs; Immunohistochemistry; Intestine, Small; Membrane Potentials; Muscimol; Myenteric Plexus; Neurons; Pentobarbital; Receptors, GABA-A; S100 Calcium Binding Protein G | 2000 |
Intrastriatal administration of 5-aminolevulinic acid induces convulsions and body asymmetry through glutamatergic mechanisms.
Topics: Aminolevulinic Acid; Animals; Convulsants; Corpus Striatum; Dizocilpine Maleate; Epilepsy; Excitatory Amino Acid Antagonists; Female; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Microinjections; Muscimol; Quinoxalines; Rats; Rats, Wistar | 2000 |
Participation of GABAergic and histaminergic systems in inhibiting amygdaloid kindled seizures.
Topics: Amygdala; Animals; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Histamine; Imidazoles; Kindling, Neurologic; Male; Muscimol; Rats; Rats, Wistar; Seizures; Thiourea; Valproic Acid | 2000 |
GABA in the deep layers of the superior Colliculus/Mesencephalic reticular formation mediates the enhancement of startle by the dopamine D1 receptor agonist SKF 82958 in rats.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Benzazepines; Bicuculline; Catheterization; Dopamine Agonists; Dose-Response Relationship, Drug; Fluorescent Dyes; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Immunohistochemistry; Male; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Reflex, Startle; Reticular Formation; Stilbamidines; Superior Colliculi | 2000 |
Local GABAergic modulation of acetylcholine release from the cortex of freely moving rats.
Topics: Acetylcholine; Animals; Baclofen; Bicuculline; Brain Chemistry; Cerebral Cortex; Cholinesterase Inhibitors; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Locomotion; Male; Microdialysis; Muscimol; Organophosphorus Compounds; Physostigmine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B | 2000 |
Involvement of the medial precentral prefrontal cortex in memory consolidation for inhibitory avoidance learning in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Avoidance Learning; Dopamine; Drug Administration Routes; Excitatory Amino Acid Antagonists; GABA Agonists; gamma-Aminobutyric Acid; Male; Medial Forebrain Bundle; Memory; Muscimol; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Teaching | 2000 |
Differential modulation of proliferation in the neocortical ventricular and subventricular zones.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Antimetabolites; Bromodeoxyuridine; Cell Differentiation; Cell Division; Cell Movement; Cerebral Ventricles; Clone Cells; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fetus; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Kainic Acid; Mice; Mice, Inbred ICR; Muscimol; Neocortex; Neurons; Organ Culture Techniques; Stem Cells | 2000 |
Effects of chronic salicylate on GABAergic activity in rat inferior colliculus.
Topics: Animals; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Inferior Colliculi; Kinetics; Male; Muscimol; Neuronal Plasticity; Rats; Receptors, GABA-A; Salicylic Acid; Tinnitus | 2000 |
GAD levels and muscimol binding in rat inferior colliculus following acoustic trauma.
Topics: Animals; Cochlea; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hair Cells, Auditory; Hearing Loss, Noise-Induced; Inferior Colliculi; Male; Muscimol; Neuronal Plasticity; Rats; Rats, Inbred F344; Receptors, GABA-A; Synaptic Transmission | 2000 |
Biophysical properties and responses to neurotransmitters of petrosal and geniculate ganglion neurons innervating the tongue.
Topics: Acetylcholine; Action Potentials; Animals; Baclofen; Carotid Sinus; Cell Separation; Dose-Response Relationship, Drug; Female; Fluorescent Dyes; GABA Agonists; gamma-Aminobutyric Acid; Ganglia, Sensory; Geniculate Ganglion; In Vitro Techniques; Muscimol; Neurons; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Reaction Time; Stilbamidines; Substance P; Tongue | 2000 |
Deficit of striatal parvalbumin-reactive GABAergic interneurons and decreased basal ganglia output in a genetic rodent model of idiopathic paroxysmal dystonia.
Topics: Action Potentials; Animals; Basal Ganglia; Cell Count; Corpus Striatum; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Dystonia; Entopeduncular Nucleus; Female; GABA Agonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Immunohistochemistry; Injections, Intraperitoneal; Interneurons; Male; Mesocricetus; Microinjections; Motor Activity; Muscimol; Mutation; Neural Inhibition; Parvalbumins | 2000 |
Tone-evoked oscillations in the rat auditory cortex result from interactions between the thalamus and reticular nucleus.
Topics: Acoustic Stimulation; Animals; Auditory Cortex; Auditory Pathways; Biological Clocks; Evoked Potentials, Auditory; gamma-Aminobutyric Acid; Geniculate Bodies; Intralaminar Thalamic Nuclei; Muscimol; Neurons; Radioligand Assay; Rats; Receptors, GABA-A; Synaptic Transmission | 2000 |
Alterations in neuronal gamma-aminobutyric acid(A) receptor responsiveness in genetic models of seizure susceptibility with different expression patterns.
Topics: Age Factors; Animals; Dose-Response Relationship, Drug; Epilepsy; gamma-Aminobutyric Acid; Genetic Predisposition to Disease; Muscimol; Purkinje Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2000 |
Luteinizing hormone-releasing hormone (LHRH) biosynthesis and secretion in embryonic LHRH.
Topics: Animals; Brain Chemistry; Calcium; Culture Techniques; Female; GABA Agonists; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Hypothalamus; Mice; Muscimol; Nasal Mucosa; Neurons; Nose; Periodicity; Potassium Chloride; Pregnancy; Signal Transduction; Tetrodotoxin | 2000 |
Disinhibition in rat superior colliculus mediated by GABAc receptors.
Topics: Animals; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Interneurons; Lysine; Muscimol; Neural Inhibition; Patch-Clamp Techniques; Rats; Rats, Long-Evans; Rats, Wistar; Receptors, GABA; Superior Colliculi | 2001 |
Characterization of gamma-aminobutyrate type A receptors with atypical coupling between agonist and convulsant binding sites in discrete brain regions.
Topics: Affinity Labels; Animals; Azides; Benzodiazepines; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Cerebellum; Chickens; Convulsants; GABA Agonists; gamma-Aminobutyric Acid; Humans; Male; Muscimol; Picrotoxin; Radioligand Assay; Rats; Rats, Wistar; Receptors, GABA-A; Sesterterpenes; Sulfur Radioisotopes; Thalamus; Tritium | 2001 |
GABAergic modulation of descending inhibitory systems from the rostral ventromedial medulla (RVM). Dose-response analysis of nociception and neurological deficits.
Topics: Animals; Bicuculline; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hot Temperature; Male; Medulla Oblongata; Motor Activity; Muscimol; Pain Measurement; Pain Threshold; Rats; Rats, Wistar; Reaction Time | 2001 |
Cross-talk between excitatory and inhibitory amino acids in the regulation of growth hormone secretion in neonatal rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Baclofen; Bicuculline; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Growth Hormone; Growth Hormone-Releasing Hormone; Male; Muscimol; N-Methylaspartate; Neurosecretory Systems; Quinoxalines; Rats; Rats, Wistar; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Sex Characteristics | 2001 |
Assembly of functional alpha6beta3gamma2delta GABA(A) receptors in vitro.
Topics: Affinity Labels; Anesthetics; Animals; Anticonvulsants; Azides; Benzodiazepines; Binding Sites; Cells, Cultured; Desoxycorticosterone; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Membrane Potentials; Muscimol; Protein Structure, Tertiary; Rats; Receptors, GABA-A; Transfection; Triazoles; Tritium | 2000 |
Evidence for direct involvement of beta-catenin in phorbol ester-induced neurite outgrowth in GT1-1 hypothalamic neurones.
Topics: beta Catenin; Calcium; Cell Differentiation; Cell Division; Cell Line, Transformed; Cytoskeletal Proteins; Enzyme Inhibitors; gamma-Aminobutyric Acid; Gene Expression Regulation; Gonadotropin-Releasing Hormone; Green Fluorescent Proteins; Hypothalamus; Luminescent Proteins; Muscimol; Naphthalenes; Neurites; Neurons; Protein Kinase C; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Trans-Activators; Transfection | 2001 |
Alternative splicing of a Drosophila GABA receptor subunit gene identifies determinants of agonist potency.
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Drosophila melanogaster; Drosophila Proteins; Embryo, Nonmammalian; Exons; Female; GABA Agonists; gamma-Aminobutyric Acid; Gene Library; Genetic Variation; In Vitro Techniques; Isonicotinic Acids; Isonipecotic Acids; Membrane Potentials; Molecular Sequence Data; Muscimol; Oocytes; Patch-Clamp Techniques; Protein Subunits; Receptors, GABA-A; Recombinant Proteins; Sulfonic Acids; Xenopus laevis | 2001 |
Induction of wakefulness and inhibition of active (REM) sleep by GABAergic processes in the nucleus pontis oralis.
Topics: Animals; Baclofen; Bicuculline; Cats; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Muscimol; Neural Inhibition; Pons; Receptors, GABA-A; Reticular Formation; Sleep, REM; Wakefulness | 2001 |
GABA(A) receptors in the ventral tegmental area control bidirectional reward signalling between dopaminergic and non-dopaminergic neural motivational systems.
Topics: Animals; Bicuculline; Dopamine; Dopamine Antagonists; Drug Interactions; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Motivation; Muscimol; Neural Pathways; Neurons; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, GABA-A; Receptors, GABA-B; Reward; Signal Transduction; Synaptic Transmission; Ventral Tegmental Area | 2001 |
Attenuation of malonate toxicity in primary mesencephalic cultures using the GABA transport blocker, NO-711.
Topics: Animals; Cells, Cultured; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Malonates; Mesencephalon; Muscimol; Neurons; Nipecotic Acids; Oximes; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2001 |
A GABA-neuropeptide Y (NPY) interplay in LH release.
Topics: Animals; Brain; Female; gamma-Aminobutyric Acid; Immunohistochemistry; Luteinizing Hormone; Microscopy, Electron; Microscopy, Fluorescence; Models, Biological; Muscimol; Neurons; Neuropeptide Y; Peptides, Cyclic; Protein Binding; Rats; Rats, Sprague-Dawley; Time Factors | 2001 |
Monomeric state and ligand binding of recombinant GABA transporter from Escherichia coli.
Topics: Bacterial Proteins; Carrier Proteins; Detergents; Escherichia coli; Escherichia coli Proteins; Fluorescence; GABA Agonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Ligands; Membrane Proteins; Membrane Transport Proteins; Muscimol; Nipecotic Acids; Organic Anion Transporters; Protein Binding; Protein Structure, Quaternary; Recombinant Fusion Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thrombin | 2001 |
GABA promotes survival but not proliferation of parvalbumin-immunoreactive interneurons in rodent neostriatum: an in vivo study with stereology.
Topics: Animals; Animals, Newborn; Bicuculline; Cell Count; Cell Division; Cell Movement; Cell Survival; Embryo, Mammalian; Female; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Immunohistochemistry; Interneurons; Male; Muscimol; Neostriatum; Parvalbumins; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2001 |
Fear and feeding in the nucleus accumbens shell: rostrocaudal segregation of GABA-elicited defensive behavior versus eating behavior.
Topics: Aggression; Analysis of Variance; Animals; Appetitive Behavior; Behavior, Animal; Dose-Response Relationship, Drug; Eating; Electroshock; Fear; Feeding Behavior; GABA Agonists; gamma-Aminobutyric Acid; Microinjections; Motivation; Motor Activity; Muscimol; Nucleus Accumbens; Orientation; Rats | 2001 |
Role of human GABA(A) receptor beta3 subunit in insecticide toxicity.
Topics: Binding Sites; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Convulsants; Endosulfan; gamma-Aminobutyric Acid; Genes; Hexachlorocyclohexane; Humans; Insecticides; Muscimol; Protein Subunits; Pyrazoles; Receptors, GABA-A; Recombinant Proteins; Structure-Activity Relationship; Transfection; Tritium | 2001 |
The gamma(2)-MSH peptide mediates a central analgesic effect via a GABA-ergic mechanism that is independent from activation of melanocortin receptors.
Topics: alpha-MSH; Analgesics; Animals; Bicuculline; Catalepsy; Central Nervous System Depressants; Diazepam; Drug Interactions; Ethanol; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; gamma-MSH; Male; Mice; Mice, Inbred BALB C; Muscimol; Naloxone; Narcotic Antagonists; Nociceptors; Pain Threshold; Peptides, Cyclic; Receptors, Corticotropin; Receptors, Melanocortin; Tail | 2001 |
Lack of effect of mossy fiber-released zinc on granule cell GABA(A) receptors in the pilocarpine model of epilepsy.
Topics: Action Potentials; Animals; Dendrites; Excitatory Postsynaptic Potentials; GABA Agonists; gamma-Aminobutyric Acid; Models, Animal; Mossy Fibers, Hippocampal; Muscimol; Nerve Endings; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Status Epilepticus; Zinc | 2001 |
Estradiol enhances excitatory gamma-aminobutyric [corrected] acid-mediated calcium signaling in neonatal hypothalamic neurons.
Topics: Animals; Animals, Newborn; Calcium; Calcium Channels, L-Type; Cells, Cultured; Estradiol; gamma-Aminobutyric Acid; Glutamic Acid; Hypothalamus; Muscimol; Neurons; Rats; Signal Transduction; Time Factors | 2001 |
A GABAergic pontine reticular system is involved in the control of wakefulness and sleep.
Topics: Analysis of Variance; Animals; Bicuculline; Cats; Electroencephalography; Electromyography; Electrooculography; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Muscimol; Pons; Receptors, GABA-A; Reticular Formation; Sleep Stages; Wakefulness | 1999 |
Involvement of central GABAergic neurons in basal and diurnal changes of tuberoinfundibular dopaminergic neuronal activity and prolactin secretion.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Arcuate Nucleus of Hypothalamus; Baclofen; Circadian Rhythm; Dopamine; Female; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Median Eminence; Muscimol; Neurons; Prolactin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B | 2001 |
GABA inhibition of immortalized gonadotropin-releasing hormone neuronal excitability involves GABA(A) receptors negatively coupled to cyclic adenosine monophosphate formation.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Baclofen; Bicuculline; Calcium; Calcium Channels; Cell Line, Transformed; Cell Membrane; Colforsin; Cyclic AMP; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Kinetics; Muscimol; Neurons; Potassium; Receptors, GABA-A | 2001 |
Significance of GABAergic systems in the action of improgan, a non-opioid analgesic.
Topics: Analgesics, Non-Narcotic; Animals; Cimetidine; gamma-Aminobutyric Acid; Male; Morphine; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2001 |
Inhibition of the substantia nigra suppresses absences and clonic seizures in audiogenic rats, but not tonic seizures: evidence for seizure specificity of the nigral control.
Topics: Acoustic Stimulation; Animals; Auditory Pathways; Electroencephalography; Epilepsy, Absence; Epilepsy, Reflex; GABA Agonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Muscimol; Nerve Net; Neural Inhibition; Neurons; Radioligand Assay; Rats; Rats, Wistar; Receptors, GABA-A; Seizures; Substantia Nigra | 2001 |
GABA enhances transmission at an excitatory glutamatergic synapse.
Topics: Animals; Baclofen; Electric Stimulation; Excitatory Postsynaptic Potentials; Female; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Ganglia, Invertebrate; Glutamic Acid; In Vitro Techniques; Iontophoresis; Male; Membrane Potentials; Motor Neurons; Muscimol; Muscles; Nephropidae; Neuromuscular Junction; Patch-Clamp Techniques; Picrotoxin; Receptors, GABA-B; Synapses; Synaptic Transmission | 2001 |
Contribution of the Na-K-Cl cotransporter on GABA(A) receptor-mediated presynaptic depolarization in excitatory nerve terminals.
Topics: Animals; Bumetanide; Carrier Proteins; Chlorides; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Hypothalamus; In Vitro Techniques; Muscimol; Neurons; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, GABA-A; Sodium-Potassium-Chloride Symporters; Synaptic Transmission; Tetrodotoxin; Ventromedial Hypothalamic Nucleus | 2001 |
Involvement of GABAergic systems in manifestation of pharmacological activity of desipramine.
Topics: Animals; Antidepressive Agents, Tricyclic; Baclofen; Desipramine; Freund's Adjuvant; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Muscimol; Picrotoxin; Rats; Rats, Sprague-Dawley; Reaction Time | 2001 |
Nitric oxide inhibits GABA-evoked current in dorsal root ganglion neuron via PKG-dependent pathway.
Topics: Animals; Cyclic GMP-Dependent Protein Kinases; Electric Conductivity; Enzyme Inhibitors; GABA Agonists; gamma-Aminobutyric Acid; Ganglia, Spinal; Male; Methylene Blue; Muscimol; Neurons, Afferent; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Rats; Rats, Sprague-Dawley | 2001 |
alpha4beta3delta GABA(A) receptors characterized by fluorescence resonance energy transfer-derived measurements of membrane potential.
Topics: Animals; Benzodiazepines; Cell Line; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Humans; Membrane Potentials; Mice; Models, Biological; Muscimol; Pentobarbital; Pregnanediones; Pregnanolone; Protein Binding; Protein Conformation; Receptors, GABA-A; Spectrometry, Fluorescence; Time Factors; Transfection | 2001 |
The testosterone metabolite and neurosteroid 3alpha-androstanediol may mediate the effects of testosterone on conditioned place preference.
Topics: Androgens; Androstane-3,17-diol; Animals; Chloride Channels; Conditioning, Operant; Dihydrotestosterone; GABA Agonists; gamma-Aminobutyric Acid; Male; Muscimol; Organ Size; Radioimmunoassay; Rats; Receptors, Androgen; Receptors, GABA-A; Seminal Vesicles; Testosterone | 2001 |
The motor inhibitory system operating during active sleep is tonically suppressed by GABAergic mechanisms during other states.
Topics: Animals; Bicuculline; Carbachol; Cats; Chlorides; Cholinergic Agents; Electrophysiology; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Microinjections; Motor Neurons; Muscimol; Muscle Tonus; Neural Inhibition; Reflex; Reticular Formation; Sleep; Spinal Cord; Synapses | 2001 |
GABA receptors modulate trigeminovascular nociceptive neurotransmission in the trigeminocervical complex.
Topics: Animals; Baclofen; Bicuculline; Cats; Evoked Potentials; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Muscimol; Neurons; Nociceptors; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Synaptic Transmission; Time Factors; Trigeminal Nuclei | 2001 |
Role of GABA within the nucleus tractus solitarii in the hypoxic ventilatory decline of awake rats.
Topics: Animals; Baclofen; Bicuculline; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hypoxia; Male; Microdialysis; Microinjections; Muscimol; Neurons; Organophosphorus Compounds; Pulmonary Ventilation; Rats; Rats, Sprague-Dawley; Solitary Nucleus | 2001 |
Regulation of the expression of low affinity GABAA receptors in rat cerebellar granule cells.
Topics: Animals; Animals, Newborn; Cells, Cultured; Cerebellum; Enzyme Inhibitors; GABA Agonists; gamma-Aminobutyric Acid; Genistein; Insulin-Like Growth Factor I; Muscimol; Neurons; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Tritium | 2001 |
Postnatal maturation of GABA(A) and GABA(C) receptor function in the mammalian superior colliculus.
Topics: Aging; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Interneurons; Membrane Potentials; Muscimol; Neural Inhibition; Neural Pathways; Patch-Clamp Techniques; Rats; Rats, Long-Evans; Receptors, GABA; Receptors, GABA-A; Superior Colliculi; Synaptic Transmission | 2001 |
The activation of gamma aminobutyric acid(A) receptors in the paraventricular nucleus of the hypothalamus reduces non-contact penile erections in male rats.
Topics: Animals; Baclofen; Copulation; Dose-Response Relationship, Drug; Female; GABA Agonists; GABA-A Receptor Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Male; Microinjections; Muscimol; Neural Inhibition; Neural Pathways; Neurons; Paraventricular Hypothalamic Nucleus; Penile Erection; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Synaptic Transmission | 2001 |
Sexual dimorphism and developmental regulation of substantia nigra function.
Topics: Aging; Animals; Animals, Newborn; Castration; Convulsants; Disease Susceptibility; Female; GABA Agonists; gamma-Aminobutyric Acid; Male; Microinjections; Muscimol; Rats; Rats, Sprague-Dawley; Seizures; Sex Characteristics; Sex Factors; Substantia Nigra; Testosterone | 2001 |
Modulation of audiogenically kindled seizures by gamma-aminobutyric acid-related mechanisms in the amygdala.
Topics: Acoustic Stimulation; Amygdala; Animals; Epilepsy; GABA Agonists; gamma-Aminobutyric Acid; Genetic Predisposition to Disease; Histamine; Kindling, Neurologic; Muscimol; Rats; Rats, Mutant Strains; Receptors, GABA-A; Receptors, Histamine | 2001 |
Hippocampal hyperexcitability induced by GABA withdrawal is due to down-regulation of GABA(A) receptors.
Topics: Animals; Bicuculline; Down-Regulation; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Kinetics; Male; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A; Substance Withdrawal Syndrome | 2001 |
Tonic activity and GABA responsiveness of medial vestibular nucleus neurons in aged rats.
Topics: Aging; Animals; Baclofen; Dose-Response Relationship, Drug; GABA Agonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Neuronal Plasticity; Neurons; Rats; Rats, Inbred Strains; Receptors, GABA-A; Vestibular Nuclei | 2001 |
GABA(A) and GABA(B) receptors in the anterior piriform cortex modulate feeding in rats.
Topics: Amino Acids; Animals; Baclofen; Bicuculline; Feeding Behavior; Food Deprivation; Food, Formulated; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Neural Inhibition; Neurons; Olfactory Pathways; Oligonucleotide Array Sequence Analysis; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; RNA, Messenger; Threonine | 2002 |
Activation of alpha 6 GABAA receptors on depolarized cerebellar parallel fibers elicits glutamate release through anion channels.
Topics: Animals; Calcium Channels; Cerebellum; GABA Agonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Membrane Potentials; Muscimol; Nerve Fibers; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2001 |
Binding and neuropharmacological profile of zaleplon, a novel nonbenzodiazepine sedative/hypnotic.
Topics: Acetamides; Animals; Benzodiazepinones; Electroencephalography; Flunitrazepam; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Male; Muscimol; Pyrimidines; Rabbits; Rats; Rats, Sprague-Dawley; Sleep | 2002 |
Cholinergic transmission via central synapses in the locust nervous system.
Topics: Acetylcholine; Animals; Atropine; Bicuculline; Bungarotoxins; Carbachol; Crotonates; gamma-Aminobutyric Acid; Ganglia, Invertebrate; Glutamic Acid; Grasshoppers; Interneurons; Muscimol; Neurons, Afferent; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Picrotoxin; Receptors, Nicotinic; Synapses; Synaptic Transmission; Tubocurarine | 2001 |
Inhibition of the hypothalamic paraventricular nucleus in spontaneously hypertensive rats dramatically reduces sympathetic vasomotor tone.
Topics: Animals; Bicuculline; Blood Pressure; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; Hypertension; Male; Medulla Oblongata; Muscimol; Paraventricular Hypothalamic Nucleus; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sympathetic Nervous System | 2002 |
Interference with the GABAergic system in the dorsolateral telencephalon and modulation of the electric organ discharge frequency in the weakly electric fish Gymnotus carapo.
Topics: Animals; Bicuculline; Dose-Response Relationship, Drug; Electric Organ; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Gymnotiformes; Motor Activity; Muscimol; Telencephalon | 2001 |
Reduced endogenous GABA-mediated inhibition in the PVN on renal nerve discharge in rats with heart failure.
Topics: Animals; Bicuculline; Blood Pressure; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Heart Failure; Heart Rate; Kidney; Male; Microinjections; Muscimol; Neural Inhibition; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System | 2002 |
GABA mediates steroid-induced astrocyte differentiation in the neonatal rat hypothalamus.
Topics: Animals; Animals, Newborn; Astrocytes; Blotting, Western; Cell Differentiation; Female; GABA Agonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Glutamate Decarboxylase; Hypothalamus; Immunohistochemistry; Muscimol; Oligonucleotides, Antisense; Rats; RNA, Messenger; Steroids | 2002 |
Reduction of drug-induced yawning and penile erection and of noncontact erections in male rats by the activation of GABAA receptors in the paraventricular nucleus: involvement of nitric oxide.
Topics: Animals; Apomorphine; Baclofen; Bicuculline; Copulation; Extracellular Space; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; N-Methylaspartate; Neural Inhibition; Nitrates; Nitric Oxide; Nitrites; Oxytocin; Paraventricular Hypothalamic Nucleus; Penile Erection; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Yawning | 2002 |
Mechanism underlying gamma-aminobutyric acid-induced antihypertensive effect in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Baclofen; Blood Pressure; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Mesenteric Arteries; Methoxamine; Muscimol; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Species Specificity; Systole; Time Factors; Vasoconstriction; Vasoconstrictor Agents | 2002 |
Altered receptor subtypes in the forebrain of GABA(A) receptor delta subunit-deficient mice: recruitment of gamma 2 subunits.
Topics: Affinity Labels; Animals; Azides; Benzodiazepines; Binding Sites; Brain; Female; GABA Agonists; gamma-Aminobutyric Acid; Ion Channels; Male; Mice; Mice, Knockout; Muscimol; Mutation; Neural Inhibition; Neurons; Radioligand Assay; Receptors, GABA-A; Synaptic Transmission; Tritium | 2002 |
GABA interacts with photic signaling in the suprachiasmatic nucleus to regulate circadian phase shifts.
Topics: Animals; Baclofen; Circadian Rhythm; Cricetinae; Excitatory Amino Acid Agonists; GABA Agonists; GABA-A Receptor Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Mesocricetus; Muscimol; N-Methylaspartate; Neural Inhibition; Neurons; Photic Stimulation; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Suprachiasmatic Nucleus; Synaptic Transmission; Tetrodotoxin | 2002 |
The interaction of morphine and gamma-aminobutyric acid (GABA)ergic systems in anxiolytic behavior: using mu-opioid receptor knockout mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Brain; Estrogens; Estrous Cycle; Female; GABA Agonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Maze Learning; Mice; Mice, Knockout; Morphine; Muscimol; Naloxone; Narcotic Antagonists; Neural Inhibition; Neural Pathways; Neurons; Receptors, GABA-A; Receptors, Opioid, mu; Synaptic Transmission | 2002 |
Subunit composition and function of GABAA receptors of rat spermatozoa.
Topics: Animals; Base Sequence; Bicuculline; DNA Primers; gamma-Aminobutyric Acid; Male; Muscimol; Picrotoxin; Protein Subunits; Rats; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spermatozoa; Transcription, Genetic | 2002 |
GABA(A) receptor activation at medullary sympathetic neurons contributes to postexercise hypotension.
Topics: Animals; Baroreflex; Bicuculline; Blood Pressure; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hypotension; Male; Medulla Oblongata; Muscimol; Neurons; Physical Exertion; Random Allocation; Rats; Rats, Inbred SHR; Receptors, GABA-A; Signal Transduction; Sympathetic Nervous System | 2002 |
The sleep hormone oleamide modulates inhibitory ionotropic receptors in mammalian CNS in vitro.
Topics: Animals; Biological Transport, Active; Brain; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Female; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glycine; Humans; Hypnotics and Sedatives; Male; Mice; Muscimol; Oleic Acids; Oocytes; Radioligand Assay; Receptors, GABA-A; Receptors, Glycine; Sleep; Synaptic Membranes; Tritium; Xenopus laevis | 2002 |
Manipulation of inhibition in the owl's nucleus laminaris and its effects on optic tectum neurons.
Topics: Animals; Brain; GABA Agonists; gamma-Aminobutyric Acid; Injections; Muscimol; Neural Inhibition; Neurons; Receptors, GABA-A; Sound Localization; Strigiformes; Superior Colliculi | 2002 |
Modulation Of [35S]-tert-butylbicyclophosphorothionate binding by somatostatin in rat hypothalamus.
Topics: Animals; Bicuculline; Binding Sites; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Convulsants; Dose-Response Relationship, Drug; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hypothalamus; Male; Muscimol; Pregnanolone; Rats; Rats, Wistar; Receptors, GABA-A; Somatostatin; Sulfur Radioisotopes | 2002 |
Effects of striatal injections of GABA(A) receptor agonists and antagonists in a genetic animal model of paroxysmal dystonia.
Topics: Animals; Bicuculline; Binding Sites; Corpus Striatum; Cricetinae; Dystonia; Female; Flumazenil; Flurazepam; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Male; Mesocricetus; Microinjections; Muscimol; Pentylenetetrazole; Phenobarbital | 2002 |
Inhibition of GABAergic neurotransmission in the ventral tegmental area by cannabinoids.
Topics: Analgesics; Animals; Animals, Newborn; Benzoxazines; Cannabinoids; Drug Interactions; GABA Agonists; gamma-Aminobutyric Acid; Membrane Potentials; Morpholines; Muscimol; Naphthalenes; Neural Inhibition; Neural Pathways; Neurons; Nucleus Accumbens; Organ Culture Techniques; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Receptors, GABA-A; Rimonabant; Synaptic Transmission; Ventral Tegmental Area | 2002 |
GABAergic mechanisms in the pedunculopontine tegmental nucleus of the cat promote active (REM) sleep.
Topics: Action Potentials; Animals; Bicuculline; Cats; Cholinergic Fibers; Eye Movements; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Muscimol; Neural Inhibition; Neurons; Pons; Receptors, GABA-A; Reticular Formation; Sleep; Sleep, REM; Tegmentum Mesencephali; Wakefulness | 2002 |
GABAergic modulation of primary gustatory afferent synaptic efficacy.
Topics: Animals; Baclofen; Bicuculline; Carrier Proteins; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; GABA Plasma Membrane Transport Proteins; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Goldfish; Membrane Proteins; Membrane Transport Proteins; Muscimol; Neurons, Afferent; Organic Anion Transporters; Phosphinic Acids; Propanolamines; Receptors, GABA-A; Receptors, GABA-B; Solitary Nucleus; Synapses; Taste | 2002 |
GABAergic control of food intake in the meat-type chickens.
Topics: Animals; Baclofen; Bicuculline; Chickens; Dose-Response Relationship, Drug; Eating; GABA Agents; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Meat; Muscimol | 2002 |
GABA and development of the Xenopus optic projection.
Topics: Analysis of Variance; Animals; Baclofen; Blotting, Western; Culture Techniques; Dose-Response Relationship, Drug; Embryo, Nonmammalian; Embryonic Development; Epithelial Cells; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Immunohistochemistry; Muscimol; Neurites; Neurons; Organophosphorus Compounds; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Retinal Ganglion Cells; Visual Pathways; Xenopus laevis | 2002 |
Peripheral GABAergic inhibition of spider mechanosensory afferents.
Topics: Afferent Pathways; Animals; Bicuculline; Dose-Response Relationship, Drug; Electrophysiology; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Muscimol; Neural Inhibition; Neurons, Afferent; Patch-Clamp Techniques; Picrotoxin; Sodium Channels; Spiders | 2002 |
Detection of molecules related to the GABAergic system in a single-cell eukaryote, Paramecium primaurelia.
Topics: 4-Aminobutyrate Transaminase; Acetylcholine; Aldehyde Oxidoreductases; Animals; Antibodies; Bicuculline; Boron Compounds; Choline O-Acetyltransferase; Fluorescent Dyes; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Immunohistochemistry; Muscimol; Paramecium; Picrotoxin; Receptors, GABA-A | 2002 |
Excitatory actions of GABA increase BDNF expression via a MAPK-CREB-dependent mechanism--a positive feedback circuit in developing neurons.
Topics: Animals; Bicuculline; Blotting, Western; Brain-Derived Neurotrophic Factor; Calcium; Cell Culture Techniques; Cyclic AMP Response Element-Binding Protein; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus; Immunohistochemistry; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Muscimol; Nerve Growth Factor; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Signal Transduction | 2002 |
Positive and negative motivation in nucleus accumbens shell: bivalent rostrocaudal gradients for GABA-elicited eating, taste "liking"/"disliking" reactions, place preference/avoidance, and fear.
Topics: Animals; Behavior, Animal; Conditioning, Psychological; Eating; Fear; Feeding Behavior; Female; GABA Agonists; gamma-Aminobutyric Acid; Male; Microinjections; Motivation; Muscimol; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Spatial Behavior; Taste | 2002 |
Differential effects of bicuculline and muscimol microinjections into the nucleus basalis magnocellularis in taste and place aversive memory formation.
Topics: Animals; Avoidance Learning; Basal Nucleus of Meynert; Bicuculline; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Memory; Microinjections; Muscimol; Rats; Rats, Wistar; Saccharin; Taste | 2002 |
GABAergic and glutamatergic terminals differentially influence the organization of GABAergic synapses in rat cerebellar granule cells in vitro.
Topics: Age Factors; Animals; Animals, Newborn; Bicuculline; Carrier Proteins; Cell Differentiation; Cells, Cultured; Cerebellar Cortex; Fluorescent Antibody Technique; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Isoxazoles; Membrane Proteins; Membrane Transport Proteins; Muscimol; Presynaptic Terminals; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptic Membranes; Synaptic Transmission; Vesicular Glutamate Transport Protein 1; Vesicular Transport Proteins | 2002 |
GABAergic and glutamatergic afferents in the dorsal raphe nucleus mediate morphine-induced increases in serotonin efflux in the rat central nervous system.
Topics: Analgesics, Opioid; Animals; Central Nervous System; Excitatory Amino Acid Agonists; GABA Agonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Microdialysis; Microinjections; Morphine; Muscimol; Naltrexone; Narcotic Antagonists; Neurons, Afferent; Nucleus Accumbens; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Serotonin | 2002 |
GABAergic systems in the nucleus tractus solitarius regulate noradrenaline release in the subfornical organ area in the rat.
Topics: Analysis of Variance; Animals; Baclofen; Bicuculline; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Microdialysis; Muscimol; Norepinephrine; Rats; Rats, Wistar; Solitary Nucleus; Subfornical Organ | 2002 |
GABA-mediated neurotransmission in the ventrolateral NTS plays a role in respiratory regulation in the rat.
Topics: Animals; Apnea; Baclofen; Bicuculline; Cardiovascular System; Fluorescent Antibody Technique; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemistry; Kynurenic Acid; Male; Microinjections; Muscimol; Nipecotic Acids; Rats; Rats, Sprague-Dawley; Receptors, GABA; Respiration; Synaptic Transmission; Ventral Thalamic Nuclei | 2002 |
GABAergic regulation of the central nucleus of the amygdala: implications for sleep control.
Topics: Amygdala; Animals; Bicuculline; Electroencephalography; Electromyography; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Neural Inhibition; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sleep; Sleep, REM; Wakefulness | 2002 |
Activation of A-type gamma-aminobutyric acid receptors excites gonadotropin-releasing hormone neurons.
Topics: Action Potentials; Animals; Cell Line, Transformed; Chlorides; Electric Conductivity; Female; gamma-Aminobutyric Acid; Gene Expression; Gonadotropin-Releasing Hormone; Gramicidin; Green Fluorescent Proteins; Homeostasis; Immunohistochemistry; In Situ Hybridization; K Cl- Cotransporters; Luminescent Proteins; Male; Membrane Potentials; Mice; Mice, Transgenic; Muscimol; Neurons; Patch-Clamp Techniques; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Recombinant Fusion Proteins; RNA, Messenger; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Symporters | 2002 |
Role of serotonin, gamma-aminobutyric acid, and glutamate in the behavioral thermoregulation of female tilapia during the prespawning phase.
Topics: Animals; Behavior, Animal; Body Temperature Regulation; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Female; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Hypothalamus; Muscimol; N-Methylaspartate; Reproduction; Serotonin; Tilapia; Time Factors | 2002 |
Plasticity of gamma-aminobutyrate receptors in the medial vestibular nucleus of rat after inferior cerebellar peduncle transection.
Topics: Animals; Baclofen; Behavior, Animal; Electrophysiology; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Potentials; Mesencephalon; Muscimol; Neuronal Plasticity; Rats; Rats, Sprague-Dawley; Receptors, GABA; Vestibular Nuclei | 2002 |
Photoaffinity labeling with a neuroactive steroid analogue. 6-azi-pregnanolone labels voltage-dependent anion channel-1 in rat brain.
Topics: Affinity Labels; Animals; Aziridines; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cell Membrane; Female; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Kinetics; Membrane Potentials; Muscimol; Oocytes; Porins; Pregnanolone; Rats; Recombinant Proteins; Steroids; Telencephalon; Transfection; Voltage-Dependent Anion Channel 1; Voltage-Dependent Anion Channels; Xenopus laevis | 2003 |
GABAB receptor-mediated presynaptic potentiation of ATP ionotropic receptors in rat midbrain synaptosomes.
Topics: Adenosine Triphosphate; Animals; Baclofen; Calcium; Colforsin; Competitive Bidding; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Fura-2; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Immunohistochemistry; In Vitro Techniques; Mesencephalon; Muscimol; Nerve Tissue Proteins; Picrotoxin; Rats; Receptors, GABA-B; Receptors, Purinergic P2; Receptors, Purinergic P2X; Synaptosomes; Time Factors | 2003 |
GABAergic modulation of hippocampal glutamatergic neurons: an in vivo microdialysis study.
Topics: Animals; Baclofen; Calcium; Calcium Channel Blockers; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Microdialysis; Muscimol; Neurons; Potassium Chloride; Rats; Receptors, GABA; Synaptosomes; Taurine; Time Factors; Veratridine | 2003 |
GABAergic regulation of REM sleep in reticularis pontis oralis and caudalis in rats.
Topics: Animals; Bicuculline; Electroencephalography; Electromyography; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Microinjections; Muscimol; Neural Inhibition; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Reticular Formation; Sleep, REM | 2003 |
Interactions of taurine and structurally related analogues with the GABAergic system and taurine binding sites of rabbit brain.
Topics: 4-Aminobutyrate Transaminase; Animals; Binding Sites; Brain; Drug Interactions; gamma-Aminobutyric Acid; Isomerism; Molecular Structure; Muscimol; Piperidines; Rabbits; Receptors, GABA-A; Receptors, GABA-B; Receptors, Neurotransmitter; Structure-Activity Relationship; Synaptic Membranes; Synaptosomes; Taurine; Tritium | 2003 |
Nucleus accumbens opioid, GABaergic, and dopaminergic modulation of palatable food motivation: contrasting effects revealed by a progressive ratio study in the rat.
Topics: Analgesics, Opioid; Animals; Carbohydrates; Dextroamphetamine; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Feeding Behavior; GABA Agonists; gamma-Aminobutyric Acid; Male; Motivation; Muscimol; Narcotics; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Time Factors | 2003 |
GABAergic interneurons at supraspinal and spinal levels differentially modulate the antinociceptive effect of nitrous oxide in Fischer rats.
Topics: Analgesics, Non-Narcotic; Animals; Brain; GABA Antagonists; gamma-Aminobutyric Acid; Injections, Spinal; Interneurons; Male; Muscimol; Nitrous Oxide; Pain, Postoperative; Rats; Rats, Inbred F344; Spinal Cord | 2003 |
Neuroscience. Old neurons revisit their youth.
Topics: Aging; Animals; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Macaca; Muscimol; Neurons; Photic Stimulation; Visual Cortex; Visual Perception | 2003 |
GABA and its agonists improved visual cortical function in senescent monkeys.
Topics: Aging; Animals; Bicuculline; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Macaca fascicularis; Macaca mulatta; Microelectrodes; Muscimol; Neurons; Photic Stimulation; Visual Cortex; Visual Perception | 2003 |
Distribution and binding parameters of GABAA receptors in the thalamic nuclei of Macaca mulatta and changes caused by lesioning in the globus pallidus and reticular thalamic nucleus.
Topics: Animals; Autoradiography; Basal Ganglia; Binding, Competitive; Denervation; Excitatory Amino Acid Agonists; Female; Flunitrazepam; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Globus Pallidus; Ibotenic Acid; Kainic Acid; Macaca mulatta; Male; Muscimol; Neural Pathways; Receptors, GABA-A; Thalamic Nuclei; Time Factors; Tritium | 2003 |
Switching to cue-directed behavior: specific for ventral striatal dopamine but not ventral pallidum/substantia innominata gaba as revealed by a swimming-test procedure in rats.
Topics: Animals; Basal Ganglia; Behavior, Animal; Bicuculline; Central Nervous System Stimulants; Cues; Dextroamphetamine; Dopamine; Dose-Response Relationship, Drug; Escape Reaction; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Male; Muscimol; Neural Pathways; Rats; Rats, Wistar; Substantia Innominata; Swimming | 2003 |
Adenosine suppresses the response of neurons to gaba in the superficial laminae of the rat spinal dorsal horn.
Topics: Adenosine; Alkaloids; Analgesics; Animals; Animals, Newborn; Benzophenanthridines; Bicuculline; Chelating Agents; Diglycerides; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Electric Conductivity; Enzyme Inhibitors; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Isoquinolines; Lithium; Membrane Potentials; Muscimol; Neural Inhibition; Patch-Clamp Techniques; Phenanthridines; Posterior Horn Cells; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Spinal Cord; Sulfonamides; Xanthines | 2003 |
Basal ganglia efferents to the brainstem centers controlling postural muscle tone and locomotion: a new concept for understanding motor disorders in basal ganglia dysfunction.
Topics: Animals; Atropine; Basal Ganglia; Basal Ganglia Diseases; Bicuculline; Brain Stem; Cats; Choline O-Acetyltransferase; Disease Models, Animal; Efferent Pathways; Electric Stimulation; Electromyography; Evoked Potentials, Motor; Excitatory Amino Acid Agonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Kainic Acid; Locomotion; Muscarinic Antagonists; Muscimol; Muscle Tonus; N-Methylaspartate; Neural Inhibition; Picrotoxin; Stimulation, Chemical | 2003 |
Relative involvement of globus pallidus and subthalamic nucleus in the regulation of somatodendritic dopamine release in substantia nigra is dopamine-dependent.
Topics: Animals; Dendrites; Dopamine; Dopamine Antagonists; Drug Synergism; Extracellular Space; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Glutamic Acid; Haloperidol; Male; Microdialysis; Muscimol; Neural Inhibition; Neural Pathways; Parkinson Disease; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Substantia Nigra; Subthalamic Nucleus; Synaptic Transmission | 2003 |
Enhancing and inhibitory effects of H2-receptor antagonists on the GABA and the GABAA-agonist muscimol responses of the isolated guinea pig ileum: a pharmacodynamic interaction.
Topics: Animals; Cimetidine; Dose-Response Relationship, Drug; Drug Interactions; Famotidine; Female; GABA Agonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Guinea Pigs; Histamine H2 Antagonists; Ileum; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Receptors, GABA; Receptors, GABA-A | 2003 |
On high- and low-affinity agonist sites in GABAA receptors.
Topics: Animals; Bicuculline; Binding Sites; Binding, Competitive; Cells, Cultured; Diazepam; GABA Agonists; GABA Antagonists; GABA Modulators; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Humans; Kidney; Ligands; Muscimol; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Radioligand Assay; Rats; Receptors, GABA-A; Structure-Activity Relationship; Transfection; Xenopus | 2003 |
Synaptic strength between motoneurons and terminals of the dorsolateral funiculus is regulated by GABA receptors in the turtle spinal cord.
Topics: Animals; Baclofen; Bicuculline; Electric Stimulation; Electrophysiology; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Motor Neurons; Muscimol; Picrotoxin; Receptors, GABA; Spinal Cord; Synapses; Synaptic Transmission; Time Factors; Turtles | 2004 |
GABA transmission in the ventral pallidum is not involved in the control of latent inhibition in the rat.
Topics: Amphetamine; Animals; Attention; Behavior, Animal; Central Nervous System Stimulants; Conditioning, Psychological; Dopamine Agents; Efferent Pathways; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Inhibition, Psychological; Locomotion; Male; Muscimol; Neural Inhibition; Nucleus Accumbens; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2003 |
Hypertension alters GABA receptor-mediated inhibition of neurons in the nucleus of the solitary tract.
Topics: Action Potentials; Animals; Baclofen; Baroreflex; Blood Pressure; GABA Agonists; GABA-A Receptor Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Hypertension, Renal; Male; Muscimol; Neural Inhibition; Neuronal Plasticity; Neurons; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Solitary Nucleus | 2003 |
Age-related modifications of the morphological organization of pituicytes are associated with alteration of the GABAergic and dopaminergic innervation afferent to the neurohypophysial lobe.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Afferent Pathways; Aging; Animals; Astrocytes; Axons; Cell Count; Dopamine; Dopamine Agonists; Dopamine Antagonists; Drug Interactions; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Hypothalamus; Immunohistochemistry; In Vitro Techniques; Isotonic Solutions; Male; Microscopy, Electron; Microscopy, Immunoelectron; Muscimol; Pyridazines; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, GABA-A; Sulpiride; Tyrosine 3-Monooxygenase | 2003 |
Analysis of freezing behavior and ultrasonic vocalization in response to foot-shocks, ultrasound signals and GABAergic inhibition in the inferior colliculus: effects of muscimol and midazolam.
Topics: Animals; Electric Stimulation; gamma-Aminobutyric Acid; Immobilization; Inferior Colliculi; Male; Midazolam; Muscimol; Rats; Rats, Wistar; Semicarbazides; Ultrasonics; Vocalization, Animal | 2004 |
Defense reaction mediated by NMDA mechanisms in the inferior colliculus is modulated by GABAergic nigro-collicular pathways.
Topics: Animals; Avoidance Learning; Behavior, Animal; Fear; Functional Laterality; GABA Agonists; gamma-Aminobutyric Acid; Inferior Colliculi; Microinjections; Motor Activity; Muscimol; N-Methylaspartate; Neural Inhibition; Neural Pathways; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Synaptic Transmission | 2004 |
Evidence for a role of basal ganglia in the regulation of rapid eye movement sleep by electrical and chemical stimulation for the pedunculopontine tegmental nucleus and the substantia nigra pars reticulata in decerebrate cats.
Topics: Animals; Basal Ganglia; Bicuculline; Cats; Decerebrate State; Electric Stimulation; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Muscimol; Muscle Tonus; Parkinson Disease; Pedunculopontine Tegmental Nucleus; Sleep, REM; Stimulation, Chemical; Substantia Nigra | 2004 |
GABA(A) receptors in the basolateral amygdala are involved in mediating morphine reward.
Topics: Amygdala; Analgesics, Opioid; Analysis of Variance; Animals; Behavior, Animal; Bicuculline; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Morphine; Motor Activity; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A; Reinforcement Schedule; Reward | 2004 |
Central integration of muscle reflex and arterial baroreflex in midbrain periaqueductal gray: roles of GABA and NO.
Topics: Animals; Arteries; Baroreflex; Bicuculline; Blood Pressure; Cats; Female; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Mesencephalon; Motor Activity; Muscimol; Muscle Contraction; Muscle, Skeletal; Nitric Oxide; Periaqueductal Gray; Reflex | 2004 |
Involvement of GABAergic modulation of the nucleus submedius (Sm) morphine-induced antinociception.
Topics: Analgesics, Opioid; Animals; Bicuculline; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Microinjections; Morphine; Muscimol; Naloxone; Narcotic Antagonists; Nociceptors; Pain Threshold; Rats; Rats, Sprague-Dawley; Reflex; Tail; Thalamic Nuclei | 2004 |
Medullary pathways mediating specific sympathetic responses to activation of dorsomedial hypothalamus.
Topics: Adipose Tissue, Brown; Adrenal Cortex; Animals; Bicuculline; Blood Pressure; Catecholamines; Dorsomedial Hypothalamic Nucleus; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; Kidney; Male; Medulla Oblongata; Microinjections; Muscimol; Neural Conduction; Rats; Rats, Sprague-Dawley; Reaction Time; Sympathetic Nervous System | 2004 |
5-Hydroxytryptamine 1B receptors mediate presynaptic inhibition of monosynaptic IPSC in the rat dorsolateral septal nucleus.
Topics: Analysis of Variance; Animals; Benzamides; Biphenyl Compounds; Calcium Channel Blockers; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Potentials; Muscimol; Neural Inhibition; Neurons; omega-Agatoxin IVA; omega-Conotoxin GVIA; Oxadiazoles; Patch-Clamp Techniques; Pertussis Toxin; Phosphinic Acids; Piperazines; Presynaptic Terminals; Propanolamines; Pyridines; Pyrroles; Quinoxalines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Septal Nuclei; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Synaptic Transmission | 2004 |
Modulation of the gait deficit in arthritic rats by infusions of muscimol and bicuculline.
Topics: Animals; Arthralgia; Arthritis, Experimental; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Female; GABA Agents; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Joints; Lameness, Animal; Muscimol; Neural Inhibition; Peripheral Nervous System Diseases; Rats; Rats, Inbred Lew; Reaction Time; Receptors, GABA-A; Up-Regulation | 2004 |
Circadian phase alteration by GABA and light differs in diurnal and nocturnal rodents during the day.
Topics: Analysis of Variance; Animals; Circadian Rhythm; Female; GABA Agonists; gamma-Aminobutyric Acid; Light; Male; Microinjections; Motor Activity; Muscimol; Photic Stimulation; Rats; Suprachiasmatic Nucleus | 2004 |
Peripheral GABAB agonists stimulate gastric acid secretion in mice.
Topics: Animals; Antibodies, Monoclonal; Atropine; Baclofen; Deoxyglucose; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Gastric Acid; Gastrins; Imidazoles; Injections, Intravenous; Male; Mice; Mice, Knockout; Muscimol; Organophosphorus Compounds; Pentagastrin; Peptides, Cyclic; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Receptors, Somatostatin; Somatostatin; Time Factors; Vagotomy | 2004 |
Dendritic excitability and localization of GABA-mediated inhibition in spider mechanoreceptor neurons.
Topics: Action Potentials; Animals; Dendrites; Dose-Response Relationship, Drug; Female; GABA Agonists; gamma-Aminobutyric Acid; In Vitro Techniques; Mechanoreceptors; Muscimol; Neural Inhibition; Neurons; Physical Stimulation; Spiders | 2004 |
Suprachiasmatic GABAergic inputs to the paraventricular nucleus control plasma glucose concentrations in the rat via sympathetic innervation of the liver.
Topics: Animals; Axonal Transport; Bicuculline; Blood Glucose; Circadian Rhythm; Clonidine; Corticosterone; gamma-Aminobutyric Acid; Glucagon; Gluconeogenesis; Herpesvirus 1, Suid; Hyperglycemia; Hypothalamus; Insulin; Isoproterenol; Liver; Male; Microdialysis; Muscimol; N-Methylaspartate; Norepinephrine; Parasympathectomy; Parasympathetic Nervous System; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Suprachiasmatic Nucleus; Sympathectomy; Sympathetic Nervous System; Tetrodotoxin; Vasopressins | 2004 |
Neurotransmitter analog tethered to a silicon platform for neuro-BioMEMS applications.
Topics: Avidin; Biotin; Biotinylation; gamma-Aminobutyric Acid; Molecular Structure; Muscimol; Silicon; Spectrum Analysis; Surface Properties; Wettability | 2004 |
In vitro and in vivo effects of GABA, muscimol, and bicuculline on lamprey GnRH concentration in the brain of the sea lamprey (Petromyzon marinus).
Topics: Animals; Bicuculline; Brain; Estradiol; Female; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; In Vitro Techniques; Lampreys; Muscimol; Oceans and Seas; Seawater | 2004 |
Effect of a high-salt diet on gamma-aminobutyric acid-mediated responses in the nucleus tractus solitarius of Sprague-Dawley rats.
Topics: Animals; Baclofen; Baroreflex; Bicuculline; Blood Pressure; Cardiovascular Physiological Phenomena; Dose-Response Relationship, Drug; Food, Formulated; GABA Agonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Heart Rate; Male; Muscimol; Neural Inhibition; Nipecotic Acids; Nitroprusside; Organophosphorus Compounds; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Sodium Chloride, Dietary; Solitary Nucleus | 2004 |
Charged residues at the 2' position of human GABAC rho 1 receptors invert ion selectivity and influence open state probability.
Topics: Amino Acid Sequence; Amino Acids, Cyclic; Binding Sites; Carboxylic Acids; Cations; Crotonates; Cyclopropanes; Dose-Response Relationship, Drug; Electric Conductivity; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Imidazoles; Ion Channel Gating; Isoxazoles; Molecular Sequence Data; Molecular Structure; Muscimol; Mutagenesis, Site-Directed; Proline; Protein Subunits; Receptors, GABA; Static Electricity; Structure-Activity Relationship | 2004 |
Effects of microinjections of neurotoxin AvTx8, isolated from the social wasp Agelaia vicina (Hymenoptera, Vespidae) venom, on GABAergic nigrotectal pathways.
Topics: Animals; Baclofen; GABA Agonists; gamma-Aminobutyric Acid; Male; Microinjections; Muscimol; Neural Pathways; Neurotoxins; Rats; Rats, Wistar; Stimulation, Chemical; Substantia Nigra; Superior Colliculi; Wasp Venoms; Wasps | 2005 |
Valproic acid inhibits corticotropin-releasing factor synthesis and release from the rat hypothalamus in vitro: evidence for the involvement of GABAergic neurotransmission.
Topics: Animals; Anticonvulsants; Bicuculline; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Gene Expression; Hippocampus; Male; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A; RNA, Messenger; Secretory Rate; Synaptic Transmission; Tissue Culture Techniques; Valproic Acid | 2004 |
The effects of temporary inactivation of the core and the shell subregions of the nucleus accumbens on prepulse inhibition of the acoustic startle reflex and activity in rats.
Topics: Akathisia, Drug-Induced; Animals; Artifacts; Diffusion; GABA Agonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Hyperkinesis; Male; Muscimol; Neural Inhibition; Neural Pathways; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, GABA-A; Reflex, Startle; Synaptic Transmission | 2005 |
Effects of GABAergic transmissions on the immunoreactivities of calcium binding proteins in the gerbil hippocampus.
Topics: Animals; Baclofen; Bicuculline; Calbindin 2; Calbindins; Calcium-Binding Proteins; Cell Count; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation; Gerbillinae; Hippocampus; Immunohistochemistry; Muscimol; Neurons; Parvalbumins; S100 Calcium Binding Protein G; Seizures; Synaptic Transmission | 2005 |
Role of the pedunculopontine tegmental nucleus in sensorimotor gating and reward-related behavior in rats.
Topics: Acetylcholinesterase; Animals; Behavior, Animal; Conditioning, Operant; Dose-Response Relationship, Drug; GABA Agonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Male; Mesencephalon; Microinjections; Movement; Muscimol; Pons; Rats; Rats, Wistar; Reflex, Startle; Reinforcement Schedule; Reward; Sensation | 2005 |
GABAergic modulation of the activity of globus pallidus neurons in primates: in vivo analysis of the functions of GABA receptors and GABA transporters.
Topics: Action Potentials; Animals; Anisoles; Baclofen; Brain Mapping; Enzyme Inhibitors; GABA Agonists; GABA Antagonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Globus Pallidus; Immunohistochemistry; Macaca mulatta; Membrane Transport Modulators; Membrane Transport Proteins; Microdialysis; Microscopy, Immunoelectron; Muscimol; Neurons; Nipecotic Acids; Phosphinic Acids; Propanolamines; Pyridazines; Receptors, GABA | 2005 |
Changes of body temperature and thermoregulatory responses of freely moving rats during GABAergic pharmacological stimulation to the preoptic area and anterior hypothalamus in several ambient temperatures.
Topics: Analysis of Variance; Animals; Bicuculline; Body Temperature; Body Temperature Regulation; Chromatography, High Pressure Liquid; Extracellular Space; GABA Agents; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus, Anterior; Male; Microdialysis; Muscimol; Preoptic Area; Rats; Rats, Wistar; Temperature | 2005 |
Gamma aminobutyric acid regulates glucosensitive neuropeptide Y neurons in arcuate nucleus via A/B receptors.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Baclofen; Bicuculline; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glucose; Immunohistochemistry; Male; Microscopy, Immunoelectron; Muscimol; Neurons; Neuropeptide Y; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA; Time Factors | 2005 |
GABAergic control of the ascending input from the median raphe nucleus to the limbic system.
Topics: Afferent Pathways; Animals; Baclofen; Brain Mapping; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Electroencephalography; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Limbic System; Male; Microdialysis; Muscimol; Neural Networks, Computer; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Reaction Time; Spectrum Analysis; Time Factors | 2005 |
Changes in hippocampal GABAA receptor subunit composition in bipolar 1 disorder.
Topics: Adult; Aged; Binding, Competitive; Bipolar Disorder; Brain Chemistry; Clonazepam; Female; Flumazenil; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Hippocampus; Humans; Male; Middle Aged; Muscimol; Protein Subunits; Pyridines; Radioligand Assay; Receptors, GABA-A; Schizophrenia; Zolpidem | 2005 |
Subtype-specific GABA transporter antagonists synergistically modulate phasic and tonic GABAA conductances in rat neocortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Animals, Newborn; Anisoles; Bicuculline; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Synergism; Electric Stimulation; GABA Agonists; GABA Antagonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Membrane Transport Modulators; Membrane Transport Proteins; Models, Neurological; Muscimol; Neocortex; Neural Inhibition; Neurons; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Oximes; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Time Factors | 2005 |
Electrophysiological properties and thermosensitivity of mouse preoptic and anterior hypothalamic neurons in culture.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Bicuculline; Calcium Channel Blockers; Cells, Cultured; Electric Impedance; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hypothalamus, Anterior; Immunohistochemistry; Isoenzymes; Membrane Potentials; Mice; Microtubule-Associated Proteins; Muscimol; Neural Inhibition; Neurons; Nimodipine; Patch-Clamp Techniques; Pyrimidines; Receptors, AMPA; Sodium; Sodium Channel Blockers; Temperature; Tetrodotoxin; Valine | 2005 |
In vivo co-ordinated interactions between inhibitory systems to control glutamate-mediated hippocampal excitability.
Topics: Adaptation, Physiological; Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Denervation; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Muscarinic Antagonists; Muscimol; Neural Inhibition; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Rats, Sprague-Dawley; Septal Nuclei; Synaptic Transmission; Taurine; Tritium | 2005 |
Lipopolysaccharide increases gamma-aminobutyric acid synthesis in medial preoptic neurones in association with inhibition of steroid-induced luteinising hormone surge in female rats.
Topics: Animals; Down-Regulation; Estrous Cycle; Female; GABA Agonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Isoenzymes; Lipopolysaccharides; Luteinizing Hormone; Muscimol; Neurons; Preoptic Area; Rats; Receptors, GABA-A | 2005 |
Radioligand binding studies of caloporoside and novel congeners with contrasting effects upon [35S] TBPS binding to the mammalian GABA(A) receptor.
Topics: Animals; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Flunitrazepam; gamma-Aminobutyric Acid; Glucosides; Male; Mannose; Muscimol; Radioligand Assay; Rats; Rats, Wistar; Receptors, GABA-A; Salicylates; Structure-Activity Relationship; Sulfur Radioisotopes | 2005 |
Role of GABAB receptors in GABA and baclofen-induced inhibition of adult rat cerebellar interpositus nucleus neurons in vitro.
Topics: Action Potentials; Animals; Baclofen; Bicuculline; Calcium; Cerebellar Nuclei; Dose-Response Relationship, Drug; Drug Interactions; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Magnesium; Muscimol; Neural Inhibition; Neurons; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-B | 2005 |
Allosteric positive interaction of thymol with the GABAA receptor in primary cultures of mouse cortical neurons.
Topics: Anesthetics, Intravenous; Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Chloride Channels; Computer Simulation; Female; Flunitrazepam; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; L-Lactate Dehydrogenase; Mice; Models, Molecular; Models, Neurological; Muscimol; Neurons; Neurotoxins; Pregnancy; Propidium; Propofol; Receptors, GABA-A; Thymol | 2006 |
Regulation of native GABAA receptors by PKC and protein phosphatase activity.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Analysis of Variance; Animals; Chlorides; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; GABA Agonists; gamma-Aminobutyric Acid; Isotopes; Male; Microcystins; Muscimol; Naphthalenes; Peptides, Cyclic; Phorbol 12,13-Dibutyrate; Phosphoprotein Phosphatases; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2005 |
Effects of the 5-HT(7) receptor antagonist SB-269970 microinjected into the dorsal raphe nucleus on REM sleep in the rat.
Topics: Analysis of Variance; Animals; GABA Agonists; gamma-Aminobutyric Acid; Male; Microinjections; Muscimol; Phenols; Raphe Nuclei; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Serotonin; Serotonin Antagonists; Sleep, REM; Sulfonamides | 2006 |
Increased density of GABAA receptors in the superior temporal gyrus in schizophrenia.
Topics: Adaptation, Physiological; Adult; Binding, Competitive; GABA Agonists; gamma-Aminobutyric Acid; Hallucinations; Humans; Interneurons; Male; Middle Aged; Muscimol; Nerve Degeneration; Neural Inhibition; Radioligand Assay; Receptors, GABA-A; Schizophrenia; Synaptic Transmission; Temporal Lobe; Up-Regulation | 2006 |
Direct pyrogenic input from prostaglandin EP3 receptor-expressing preoptic neurons to the dorsomedial hypothalamus.
Topics: Adipose Tissue, Brown; Animals; Blood Pressure; Body Temperature Regulation; Cell Count; Cholera Toxin; Dinoprostone; Dorsomedial Hypothalamic Nucleus; Functional Laterality; GABA Agonists; gamma-Aminobutyric Acid; Green Fluorescent Proteins; Heart Rate; Male; Models, Neurological; Muscimol; Neural Pathways; Neurons; Preoptic Area; Pyrogens; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; Sympathetic Nervous System; Transfection | 2005 |
Brain-derived neurotrophic factor silences GABA synapses onto hypothalamic neuroendocrine cells through a postsynaptic dynamin-mediated mechanism.
Topics: Animals; Brain-Derived Neurotrophic Factor; Carbazoles; Dynamins; Electrophysiology; Endocytosis; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; GABA Agonists; gamma-Aminobutyric Acid; Hypothalamus; In Vitro Techniques; Indole Alkaloids; Male; Muscimol; Neural Inhibition; Neurosecretory Systems; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptor, trkB; Receptors, GABA-A; Synapses; Synaptic Transmission | 2006 |
Balancing bilateral sensory activity: callosal processing modulates sensory transmission through the contralateral thalamus by altering the response threshold.
Topics: Action Potentials; Afferent Pathways; Animals; Corpus Callosum; Functional Laterality; GABA Agonists; gamma-Aminobutyric Acid; Mechanoreceptors; Muscimol; Neural Inhibition; Neurons; Physical Stimulation; Posterior Thalamic Nuclei; Rats; Rats, Long-Evans; Somatosensory Cortex; Thalamus; Touch; Ventral Thalamic Nuclei; Vibrissae | 2006 |
Involvement of GABAergic modulation of antinociception induced by morphine microinjected into the ventrolateral orbital cortex.
Topics: Analysis of Variance; Animals; Behavior, Animal; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Isoxazoles; Male; Microinjections; Morphine; Muscimol; Narcotics; Neurons; Nociceptors; Pain Measurement; Picrotoxin; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reaction Time | 2006 |
Hippocampal network hyperactivity after selective reduction of tonic inhibition in GABA A receptor alpha5 subunit-deficient mice.
Topics: Analysis of Variance; Animals; Animals, Newborn; Bicuculline; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Evoked Potentials; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscimol; Nerve Net; Neural Inhibition; Nipecotic Acids; Oximes; Patch-Clamp Techniques; Pyramidal Cells; Receptors, GABA-A | 2006 |
Enhancement of extinction memory consolidation: the role of the noradrenergic and GABAergic systems within the basolateral amygdala.
Topics: Adrenergic beta-Antagonists; Amygdala; Analysis of Variance; Animals; Bicuculline; Conditioning, Classical; Dose-Response Relationship, Drug; Drug Combinations; Environment; Extinction, Psychological; Fear; Functional Laterality; GABA Agents; gamma-Aminobutyric Acid; Hippocampus; Male; Memory; Microinjections; Muscimol; Norepinephrine; Propranolol; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric | 2006 |
A local GABAergic system within rat trigeminal ganglion cells.
Topics: Animals; Animals, Newborn; Bicuculline; Cell Count; Cells, Cultured; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Capacitance; Electric Stimulation; Epistasis, Genetic; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Immunohistochemistry; In Situ Hybridization; Isoenzymes; Male; Membrane Potentials; Models, Neurological; Muscimol; Neural Inhibition; Neurons; Patch-Clamp Techniques; Potassium; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Trigeminal Ganglion | 2006 |
Microinjection of muscimol into caudal periaqueductal gray lowers body temperature and attenuates increases in temperature and activity evoked from the dorsomedial hypothalamus.
Topics: Animals; Blood Pressure; Body Temperature; Body Temperature Regulation; Dorsomedial Hypothalamic Nucleus; Dose-Response Relationship, Drug; GABA Agonists; gamma-Aminobutyric Acid; Heart Rate; Male; Motor Activity; Muscimol; Neural Inhibition; Neural Pathways; Neurons; Periaqueductal Gray; Rats; Synaptic Transmission; Thermogenesis | 2006 |
Rapid inhibition of Ca2+ influx by neurosteroids in murine embryonic sensory neurones.
Topics: Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Chelating Agents; Embryo, Mammalian; Fluorescent Dyes; Fura-2; GABA Agonists; gamma-Aminobutyric Acid; Ganglia, Spinal; Membrane Proteins; Mice; Muscimol; Neurons, Afferent; Potassium Channel Blockers; Pregnanolone; Progesterone; Receptors, GABA-A; Receptors, Progesterone; Sodium Channel Blockers | 2006 |
Origins of GABA(A) and GABA(B) receptor-mediated responses of globus pallidus induced after stimulation of the putamen in the monkey.
Topics: Action Potentials; Animals; Electric Stimulation; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Macaca fascicularis; Macaca mulatta; Muscimol; Neurons; Phosphinic Acids; Propanolamines; Putamen; Pyridazines; Receptors, GABA | 2006 |
Retrograde suppression of GABAergic currents in a subset of SCN neurons.
Topics: Animals; Calcium; Chelating Agents; Circadian Rhythm; Egtazic Acid; GABA Agonists; gamma-Aminobutyric Acid; Male; Membrane Potentials; Muscimol; Neurons; Patch-Clamp Techniques; Photoperiod; Rats; Rats, Sprague-Dawley; Suprachiasmatic Nucleus; Synapses; Synaptic Transmission | 2006 |
Interaction between nociceptin/orphanin FQ (N/OFQ) and GABA in response to feeding.
Topics: Analysis of Variance; Animals; Behavior, Animal; Bicuculline; Chickens; Drug Interactions; Feeding Behavior; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Muscimol; Nociceptin; Opioid Peptides; Peptide Fragments; Time Factors | 2006 |
Characterization and restoration of altered inhibitory and excitatory control of micturition reflex in experimental autoimmune encephalomyelitis in rats.
Topics: Animals; Baclofen; Bicuculline; Cauda Equina; Efferent Pathways; Electric Stimulation; Encephalomyelitis, Autoimmune, Experimental; Female; gamma-Aminobutyric Acid; Glycine; Injections, Spinal; Lumbosacral Plexus; Models, Biological; Muscimol; Peripheral Nerves; Rats; Rats, Inbred Lew; Receptors, Glycine; Reflex, Abnormal; Spinal Cord; Strychnine; Urinary Bladder; Urinary Bladder, Neurogenic; Urinary Bladder, Overactive; Urinary Retention | 2007 |
Orexin A in the rostrolateral hypothalamic area induces feeding by modulating GABAergic transmission.
Topics: Analysis of Variance; Animals; Baclofen; Behavior, Animal; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; Eating; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamic Area, Lateral; Intracellular Signaling Peptides and Proteins; Male; Microdialysis; Muscimol; Neuropeptides; Orexins; Rats; Rats, Sprague-Dawley; Time Factors | 2006 |
Identification of a GABAA receptor anesthetic binding site at subunit interfaces by photolabeling with an etomidate analog.
Topics: Animals; Binding Sites; Blotting, Western; Brain; Cattle; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Etomidate; GABA Agonists; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Inhibitory Concentration 50; Methionine; Models, Molecular; Muscimol; Photoaffinity Labels; Radioligand Assay; Receptors, GABA; Sequence Analysis, Protein; Subcellular Fractions; Tritium | 2006 |
GABAA but not GABAB receptors in the rostral anterior cingulate cortex selectively modulate pain-induced escape/avoidance behavior.
Topics: Animals; Avoidance Learning; Baclofen; Bicuculline; Escape Reaction; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Gyrus Cinguli; Male; Microinjections; Muscimol; Pain; Pain Threshold; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B | 2007 |
Regionally selective effects of GABA on hypothalamic GABAA receptor mRNA in vitro.
Topics: Animals; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hypothalamus; Isoenzymes; Male; Muscimol; Nipecotic Acids; Oximes; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; RNA, Messenger; Tetrodotoxin | 2007 |
Earliest spontaneous activity differentially regulates neocortical GABAergic interneuron subpopulations.
Topics: Animals; Bromodeoxyuridine; Cell Differentiation; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agonists; gamma-Aminobutyric Acid; Immunohistochemistry; Interneurons; Kainic Acid; Muscimol; Neocortex; Nerve Net; Rats; Tetrodotoxin; Time Factors; Tubulin | 2007 |
Inhibitory input from slowly adapting lung stretch receptors to retrotrapezoid nucleus chemoreceptors.
Topics: Animals; Blood Pressure; Carbon Dioxide; Chemoreceptor Cells; Excitatory Amino Acid Antagonists; GABA Agonists; gamma-Aminobutyric Acid; Homeodomain Proteins; Injections, Intraventricular; Kynurenic Acid; Lung; Male; Mechanoreceptors; Medulla Oblongata; Muscimol; Neurons; Phrenic Nerve; Physical Stimulation; Positive-Pressure Respiration; Rats; Rats, Sprague-Dawley; Respiratory Mechanics; Solitary Nucleus; Transcription Factors; Vagus Nerve | 2007 |
Early functional development of interneurons in the zebrafish olfactory bulb.
Topics: Animals; Calcium; Drug Interactions; ELAV Proteins; ELAV-Like Protein 3; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation, Developmental; Green Fluorescent Proteins; Homeodomain Proteins; Imaging, Three-Dimensional; Interneurons; Muscimol; Neural Inhibition; Odorants; Olfactory Bulb; Pyridazines; Zebrafish; Zebrafish Proteins | 2007 |
GABAergic interneurons facilitate mossy fiber excitability in the developing hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Axons; Bicuculline; Cyclopropanes; Enkephalin, Methionine; Excitatory Postsynaptic Potentials; Fluorescent Dyes; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glycine; Hippocampus; Interneurons; Male; Mice; Mice, Inbred C57BL; Mossy Fibers, Hippocampal; Muscimol; Patch-Clamp Techniques; Picrotoxin; Presynaptic Terminals; Pyridazines; Pyridinium Compounds; Receptors, GABA-A; Synaptic Transmission; Tetrodotoxin | 2007 |
Role of opioidergic and GABAergic neurotransmission of the nucleus raphe magnus in the modulation of tonic immobility in guinea pigs.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Behavior, Animal; Bicuculline; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Immobility Response, Tonic; Male; Microinjections; Models, Neurological; Morphine; Muscimol; Naloxone; Narcotic Antagonists; Raphe Nuclei | 2007 |
Presynaptic GABAA receptors facilitate GABAergic transmission to dopaminergic neurons in the ventral tegmental area of young rats.
Topics: Animals; Cadmium; Dopamine; GABA Agonists; gamma-Aminobutyric Acid; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Muscimol; Neurons; Presynaptic Terminals; Protein Isoforms; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synaptic Transmission; Tetrodotoxin; Ventral Tegmental Area | 2007 |
GABAergic modulation of developing pedunculopontine nucleus.
Topics: Action Potentials; Aging; Animals; Baclofen; GABA Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Muscimol; Neural Inhibition; Neural Pathways; Pedunculopontine Tegmental Nucleus; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Reticular Formation; Sleep, REM; Sodium Channel Blockers | 2007 |
GABAergic processes in the mesencephalic tegmentum modulate the occurrence of active (rapid eye movement) sleep in guinea pigs.
Topics: Animals; Environmental Monitoring; gamma-Aminobutyric Acid; Guinea Pigs; Muscimol; Receptors, GABA-A; Sleep, REM; Tegmentum Mesencephali; Wakefulness | 2007 |
Allosteric uncoupling and up-regulation of benzodiazepine and GABA recognition sites following chronic diazepam treatment of HEK 293 cells stably transfected with alpha1beta2gamma2S subunits of GABA (A) receptors.
Topics: Allosteric Regulation; Animals; Benzodiazepines; Binding Sites; Binding, Competitive; Cell Line; Diazepam; Flumazenil; Flunitrazepam; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Muscimol; Picrotoxin; Protein Subunits; Pyridazines; Radioligand Assay; Rats; Receptors, GABA-A; Receptors, GABA-B; Transfection; Up-Regulation | 2007 |
The effects of GABA agonists on glutamic acid decarboxylase, GABA-transaminase, activin, salmon gonadotrophin-releasing hormone and tyrosine hydroxylase mRNA in the goldfish (Carassius auratus) neuroendocrine brain.
Topics: 4-Aminobutyrate Transaminase; Activins; Animals; Baclofen; Female; Fish Proteins; GABA Agonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Goldfish; Gonadotropin-Releasing Hormone; Hypothalamus; Luteinizing Hormone; Muscimol; Receptors, GABA; RNA, Messenger; Telencephalon; Tyrosine 3-Monooxygenase | 2007 |
Convulsions induced by methylmalonic acid are associated with glutamic acid decarboxylase inhibition in rats: a role for GABA in the seizures presented by methylmalonic acidemic patients?
Topics: Analysis of Variance; Animals; Baclofen; Behavior, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Electroencephalography; Excitatory Amino Acid Antagonists; GABA Agonists; gamma-Aminobutyric Acid; Gene Expression Regulation, Enzymologic; Glutamate Decarboxylase; Male; Methylmalonic Acid; Muscimol; Rats; Rats, Wistar; Seizures | 2007 |
GABAergic inactivation of basolateral amygdala alters behavioral processes other than primary reward of ventral tegmental self-stimulation.
Topics: Amygdala; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Electric Stimulation; GABA Agonists; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Ventral Tegmental Area | 2007 |
Functional evidence for GABA as modulator of the contractility of the longitudinal muscle in mouse duodenum: role of GABA(A) and GABA(C) receptors.
Topics: Animals; Bicuculline; Cytarabine; Dose-Response Relationship, Drug; Drug Interactions; Duodenum; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Mice; Mice, Inbred C57BL; Muscimol; Muscle Contraction; Muscle, Smooth; Phosphinic Acids; Pyridines; Receptors, GABA; Receptors, GABA-B | 2007 |
Exploring ligand recognition and ion flow in comparative models of the human GABA type A receptor.
Topics: Amino Acid Sequence; Benzodiazepines; Binding Sites; Computer Simulation; Flunitrazepam; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Ligands; Models, Molecular; Molecular Sequence Data; Muscimol; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, GABA-A; Sequence Homology, Amino Acid | 2007 |
GABAergic mechanisms of the lateral parabrachial nucleus on sodium appetite.
Topics: Animals; Appetite; Bicuculline; Diuretics; Drinking; Eating; Food Deprivation; Furosemide; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Organophosphorus Compounds; Pons; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sodium Chloride; Sodium, Dietary; Water Deprivation | 2007 |
Posterior hypothalamic GABAergic mediation of hippocampal theta in the cat.
Topics: Animals; Baclofen; Bicuculline; Cats; Electroencephalography; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus, Posterior; Muscimol; Rats; Theta Rhythm | 2007 |
Neonatal maternal separation and enhancement of the hypoxic ventilatory response in rat: the role of GABAergic modulation within the paraventricular nucleus of the hypothalamus.
Topics: Animals; Animals, Newborn; Anxiety, Separation; Female; Flunitrazepam; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Hypoxia; Male; Muscimol; Paraventricular Hypothalamic Nucleus; Pulmonary Ventilation; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Respiratory Mechanics; Synaptic Transmission | 2007 |
Effect of GABAergic substances on firing rate and thermal coefficient of hypothalamic neurons in the juvenile chicken.
Topics: Action Potentials; Animals; Baclofen; Bicuculline; Body Temperature Regulation; Chickens; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus; In Vitro Techniques; Muscimol; Neurons; Organophosphorus Compounds; Receptors, GABA-A; Receptors, GABA-B; Temperature; Time Factors | 2007 |
Development of chloride-mediated inhibition in neurons of the anteroventral cochlear nucleus of gerbil (Meriones unguiculatus).
Topics: Animals; Brain Stem; Chlorides; Cochlear Nucleus; Electrophysiology; Furosemide; GABA Antagonists; gamma-Aminobutyric Acid; Gerbillinae; Glycine; Muscimol; Neurons; Pyridazines; Receptors, GABA-A; Synaptic Transmission | 2007 |
GABAergic modulation of binge-like ethanol intake in C57BL/6J mice.
Topics: Alcoholism; Animals; Baclofen; Central Nervous System Depressants; Darkness; Dose-Response Relationship, Drug; Ethanol; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Isoxazoles; Male; Mice; Mice, Inbred C57BL; Muscimol; Postural Balance | 2007 |
Activation of presynaptic GABA(A) receptors induces glutamate release from parallel fiber synapses.
Topics: Animals; Animals, Newborn; Cerebellum; Electric Stimulation; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Interneurons; Microscopy, Electron, Transmission; Muscimol; Patch-Clamp Techniques; Phosphinic Acids; Presynaptic Terminals; Propanolamines; Purkinje Cells; Rats; Receptors, GABA-A; Synapses; Time Factors | 2007 |
The Cav3.2/alpha1H T-type Ca2+ current is a molecular determinant of excitatory effects of GABA in adult sensory neurons.
Topics: Animals; Baclofen; Calcium; Calcium Channel Blockers; Calcium Channels, T-Type; Cells, Cultured; Chlorides; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Female; GABA Agonists; gamma-Aminobutyric Acid; Ganglia, Spinal; Membrane Potentials; Mice; Mice, Knockout; Muscimol; Neurons, Afferent; Nickel; Patch-Clamp Techniques | 2007 |
Hippocampal infusions of glucose reverse memory deficits produced by co-infusions of a GABA receptor agonist.
Topics: Animals; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; GABA Agonists; gamma-Aminobutyric Acid; Glucose; Hippocampus; Infusion Pumps; Male; Memory Disorders; Muscimol; Pilot Projects; Rats; Rats, Sprague-Dawley; Retention, Psychology; Septum Pellucidum; Space Perception | 2008 |
Evidence for an extended duration of GABA-mediated excitation in the developing male versus female hippocampus.
Topics: Age Factors; Animals; Calcium; Calcium Channels, L-Type; Cells, Cultured; CREB-Binding Protein; Female; GABA Agents; gamma-Aminobutyric Acid; Gene Expression Regulation, Developmental; Hippocampus; K Cl- Cotransporters; Male; Muscimol; Neurons; Rats; Rats, Sprague-Dawley; Sex Characteristics; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Symporters; Time Factors | 2007 |
Sanjoinine A isolated from Zizyphi Spinosi Semen augments pentobarbital-induced sleeping behaviors through the modification of GABA-ergic systems.
Topics: Animals; Cerebellum; Chlorides; Drug Interactions; GABA Agonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hypnotics and Sedatives; Isoenzymes; Male; Mice; Mice, Inbred ICR; Muscimol; Pentobarbital; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sleep; Ziziphus | 2007 |
Involvement of the lateral prefrontal cortex in conditional suppression of gaze shift.
Topics: Animals; Cues; Fixation, Ocular; GABA Agonists; gamma-Aminobutyric Acid; Macaca; Male; Muscimol; Neural Inhibition; Neural Pathways; Neuropsychological Tests; Oculomotor Muscles; Orientation; Photic Stimulation; Prefrontal Cortex; Reaction Time; Saccades; Space Perception; Synaptic Transmission; Visual Fields; Volition | 2007 |
The involvement of the substantia nigra pars reticulata in hypoglycemic seizures.
Topics: Animals; Baclofen; Behavior, Animal; Disease Models, Animal; Fasting; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Hypoglycemia; Male; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Seizures; Substantia Nigra | 2007 |
Characteristics of GABA receptors on the ocellar L-neurons of American cockroach Periplaneta americana.
Topics: Animals; Bicuculline; Chlorides; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Iontophoresis; Membrane Potentials; Muscimol; Neurons; Periplaneta; Picrotoxin; Receptors, GABA; Sodium Chloride | 2007 |
Gamma-aminobutyric acid modulates local brain oxygen consumption and blood flow in rat cerebellar cortex.
Topics: Animals; Bicuculline; Calcium Signaling; Cerebellum; Cerebrovascular Circulation; Electrophysiology; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Models, Cardiovascular; Muscimol; Oxygen Consumption; Rats; Rats, Wistar; Receptors, GABA-A | 2008 |
Possible involvement of GABAergic modulation in the protective effect of gabapentin against immobilization stress-induced behavior alterations and oxidative damage in mice.
Topics: Amines; Animals; Behavior, Animal; Catalase; Cyclohexanecarboxylic Acids; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Glutathione; Immobilization; Mice; Motor Activity; Muscimol; Oxidation-Reduction; Picrotoxin; Stress, Psychological | 2007 |
Motor cortical control of internal pallidal activity through glutamatergic and GABAergic inputs in awake monkeys.
Topics: Action Potentials; Animals; Behavior, Animal; Bicuculline; Electric Stimulation; Female; GABA Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Glutamic Acid; Macaca fascicularis; Macaca mulatta; Male; Motor Activity; Motor Cortex; Muscimol; Neural Pathways; Neurons; Subthalamic Nucleus; Wakefulness | 2008 |
Prostaglandin E(2) fever mediated by inhibition of the GABAergic transmission in the region immediately adjacent to the organum vasculosum of the lamina terminalis.
Topics: Animals; Bicuculline; Body Temperature; Dinoprostone; Dose-Response Relationship, Drug; Fever; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; Hypothalamus; Male; Muscimol; Preoptic Area; Pyridazines; Rats; Rats, Wistar; Synaptic Transmission; Vasoconstriction | 2008 |
Contributions of voltage- and Ca2+-activated conductances to GABA-induced depolarization in spider mechanosensory neurons.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Electrophysiology; Female; gamma-Aminobutyric Acid; Ion Channel Gating; Male; Mechanoreceptors; Mibefradil; Muscimol; Neurons, Afferent; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Sodium Channels; Spiders; Tetrodotoxin | 2008 |
GABA actions in hippocampal area CA3 during postnatal development: differential shift from depolarizing to hyperpolarizing in somatic and dendritic compartments.
Topics: Age Factors; Animals; Animals, Newborn; Dendrites; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Membrane Potentials; Muscimol; Neural Inhibition; Neurons; Patch-Clamp Techniques; Pyridazines; Quinoxalines; Rats; Rats, Wistar; Valine | 2008 |
Repeated blockade of GABAA receptors in the medial septal region induces epileptiform activity in the hippocampus.
Topics: Action Potentials; Animals; Bicuculline; Biological Clocks; Electroencephalography; Epilepsy; Fornix, Brain; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Muscimol; Neural Inhibition; Neural Pathways; Neurons; Rabbits; Receptors, GABA-A; Septal Nuclei; Synaptic Transmission; Theta Rhythm | 2008 |
Evidence that gamma-aminobutyric acid is part of the neural circuit mediating estradiol negative feedback in anestrous ewes.
Topics: Anestrus; Animals; Baclofen; Bicuculline; Dopamine; Estradiol; Feedback; Female; gamma-Aminobutyric Acid; Muscimol; Neurons; Ovariectomy; Sheep | 2008 |
Cyclopeptide alkaloid fraction from Zizyphi Spinosi Semen enhances pentobarbital-induced sleeping behaviors.
Topics: Alkaloids; Animals; Cells, Cultured; Cerebellum; Chlorides; Drug Synergism; GABA Agonists; gamma-Aminobutyric Acid; Glyceraldehyde-3-Phosphate Dehydrogenases; Hypnotics and Sedatives; Male; Mice; Mice, Inbred ICR; Muscimol; Neurons; Pentobarbital; Plant Extracts; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sleep; Synaptic Transmission; Ziziphus | 2008 |
Glycinergic and GABA(A)-mediated inhibition of somatic motoneurons does not mediate rapid eye movement sleep motor atonia.
Topics: Animals; Behavior, Animal; Bicuculline; Electroencephalography; Electromyography; Excitatory Amino Acid Agents; GABA Agents; gamma-Aminobutyric Acid; Glycine; Glycine Agents; Male; Masseter Muscle; Microdialysis; Motor Neurons; Muscimol; Neural Inhibition; Rats; Rats, Sprague-Dawley; Sleep, REM; Strychnine; Trigeminal Nuclei; Wakefulness | 2008 |
Saturation assays of radioligand binding to receptors and their allosteric modulatory sites.
Topics: Allosteric Site; Animals; Binding Sites; Binding, Competitive; Flumazenil; gamma-Aminobutyric Acid; Ligands; Muscimol; Nerve Tissue Proteins; Protein Binding; Radioligand Assay; Rats; Receptors, GABA-A; Tritium | 2001 |
Gabapentin attenuates acute hypoxic stress-induced behavioral alterations and oxidative damage in mice: possible involvement of GABAergic mechanism.
Topics: Amines; Analysis of Variance; Animals; Brain; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hypoxia; Lipid Peroxidation; Mice; Motor Activity; Muscimol; Oxidative Stress; Picrotoxin; Spectrophotometry | 2008 |
GABA and histamine interaction in the basolateral amygdala of rats in the plus-maze test of anxiety-like behaviors.
Topics: Amygdala; Animals; Anxiety; Behavior, Animal; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; GABA Agents; gamma-Aminobutyric Acid; Histamine; Histamine Agents; Male; Maze Learning; Microinjections; Muscimol; Pyrilamine; Rats; Rats, Wistar | 2008 |
The basolateral nucleus of the amygdala is necessary to induce the opposing effects of stressful experience on learning in males and females.
Topics: Amygdala; Animals; Conditioning, Eyelid; Female; GABA Agonists; gamma-Aminobutyric Acid; Learning; Learning Disabilities; Male; Memory; Muscimol; Rats; Sex Characteristics; Stress, Psychological; Time Factors | 2008 |
Selective involvement of GABAergic mechanisms of the dorsal periaqueductal gray and inferior colliculus on the memory of the contextual fear as assessed by the fear potentiated startle test.
Topics: Animals; Conditioning, Classical; Fear; Freezing Reaction, Cataleptic; GABA Agonists; gamma-Aminobutyric Acid; Inferior Colliculi; Male; Memory; Muscimol; Periaqueductal Gray; Rats; Rats, Wistar; Reflex, Startle | 2008 |
Diencephalic locomotor region in the lamprey--afferents and efferent control.
Topics: Animals; Behavior, Animal; Biotin; Brain Mapping; Diencephalon; Dose-Response Relationship, Radiation; Electric Stimulation; Electromyography; Functional Laterality; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Lampreys; Locomotion; Muscimol; Neural Pathways; Pyridazines | 2008 |
Transport of amino acids and GABA analogues via the human proton-coupled amino acid transporter, hPAT1: characterization of conditions for affinity and transport experiments in Caco-2 cells.
Topics: Algorithms; Amino Acid Transport Systems; Amino Acids; Biological Transport, Active; Caco-2 Cells; GABA Agonists; gamma-Aminobutyric Acid; Glycine; Humans; Hydrogen-Ion Concentration; Isoxazoles; Kinetics; Ligands; Muscimol; Neurotransmitter Uptake Inhibitors; Osmolar Concentration; Proline; Symporters | 2008 |
Gabaergic mechanisms of hypothalamic nuclei in the expression of conditioned fear.
Topics: Analysis of Variance; Animals; Association Learning; Conditioning, Operant; Dorsomedial Hypothalamic Nucleus; Enzyme Inhibitors; Fear; GABA Agonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hypothalamus; Hypothalamus, Anterior; Male; Muscimol; Rats; Rats, Wistar; Reflex, Startle; Semicarbazides; Signal Transduction; Ventromedial Hypothalamic Nucleus | 2008 |
Activation of the GABA(A) receptor ameliorates the cochlear excitotoxicity caused by kainic acid in the guinea pig.
Topics: Acoustics; Action Potentials; Animals; Baclofen; Bicuculline; Cochlea; Electrophysiology; GABA Agonists; gamma-Aminobutyric Acid; Glutamine; Guinea Pigs; Kainic Acid; Muscimol; Neurons; Receptors, GABA-A | 2008 |
Synthesis of GABAA receptor agonists and evaluation of their alpha-subunit selectivity and orientation in the GABA binding site.
Topics: Animals; Binding Sites; Brain; Cell Line; Electrophysiology; Female; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Humans; Isoxazoles; Models, Molecular; Molecular Structure; Muscimol; Mutation; Oocytes; Patch-Clamp Techniques; Piperidines; Protein Subunits; Rats; Receptors, GABA-A; Structure-Activity Relationship; Xenopus laevis | 2008 |
Impact of estradiol on gamma-aminobutyric acid- and glutamate-mediated calcium responses of fetal baboon (Papio anubis) hippocampal and cortical neurons.
Topics: Animals; Blotting, Western; Calcium; Cells, Cultured; Cerebral Cortex; Estradiol; Fetus; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Immunohistochemistry; Intracellular Space; Muscimol; Neurons; Papio | 2008 |
Nucleus accumbens adenosine A2A receptors regulate exertion of effort by acting on the ventral striatopallidal pathway.
Topics: Adenosine; Analysis of Variance; Animals; Behavior, Animal; Cholera Toxin; Conditioning, Operant; Dose-Response Relationship, Drug; GABA Agonists; gamma-Aminobutyric Acid; Globus Pallidus; Male; Muscimol; Neostriatum; Neural Pathways; Nucleus Accumbens; Phenethylamines; Physical Exertion; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Reinforcement Schedule; Vasoactive Intestinal Peptide | 2008 |
GABAergic mechanism of propofol toxicity in immature neurons.
Topics: Aging; Anesthetics, Intravenous; Animals; Calcium; Calcium Channel Agonists; Calcium Channels, L-Type; Caspase 3; Caspase 7; Cell Death; Cells, Cultured; Electrophysiology; GABA Agonists; gamma-Aminobutyric Acid; Hippocampus; Microscopy, Fluorescence; Muscimol; Neurons; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2008 |
GABAA receptors in the central nucleus of amygdala (CeA) affect on pain modulation.
Topics: Amygdala; Animals; Bicuculline; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Microinjections; Muscimol; Neural Inhibition; Nociceptors; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Wistar; Reaction Time; Receptors, GABA-A; Synaptic Transmission | 2008 |
Sustained depolarizing shift of the GABA reversal potential by glutamate receptor activation in hippocampal neurons.
Topics: Analysis of Variance; Animals; Bumetanide; Calcium; Chlorides; Electric Stimulation; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Agents; Furosemide; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Membrane Potentials; Muscimol; Neural Inhibition; Neural Pathways; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Receptors, Glutamate; Sodium Potassium Chloride Symporter Inhibitors; Time Factors | 2008 |
Random stimulation of spider mechanosensory neurons reveals long-lasting excitation by GABA and muscimol.
Topics: Algorithms; Animals; Bumetanide; Carrier Proteins; Chlorides; Diuretics; Electric Stimulation; Furosemide; GABA Agonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Mechanotransduction, Cellular; Muscimol; Patch-Clamp Techniques; Physical Stimulation; Sensory Receptor Cells; Spiders | 2009 |
Resting intracellular calcium concentration, depolarizing Gamma-Aminobutyric Acid and possible role of local estradiol synthesis in the developing male and female hippocampus.
Topics: Androstenedione; Animals; Animals, Newborn; Aromatase Inhibitors; Calcium; Cells, Cultured; Chelating Agents; Egtazic Acid; Estradiol; Estrogen Antagonists; Excitatory Amino Acid Agents; Extracellular Fluid; Female; Fulvestrant; GABA Agonists; gamma-Aminobutyric Acid; Gene Expression Regulation; Hippocampus; Male; Muscimol; Neurons; Organophosphonates; Piperazines; Rats; Rats, Sprague-Dawley; Sex Characteristics; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2 | 2009 |
Understanding your inhibitions: effects of GABA and GABAA receptor modulation on brain cortical metabolism.
Topics: Allosteric Regulation; Animals; Carbon Isotopes; Cerebral Cortex; Discriminant Analysis; Dose-Response Relationship, Drug; GABA Agonists; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Ligands; Muscimol; Principal Component Analysis; Pyruvic Acid; Receptors, GABA-A; Statistics, Nonparametric; Tritium | 2009 |
Memory consolidation and reconsolidation in an invertebrate model: the role of the GABAergic system.
Topics: Analysis of Variance; Animals; Avoidance Learning; Bicuculline; Brachyura; Conditioning, Classical; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Memory; Models, Animal; Muscimol | 2009 |
Modulation of GABAergic and glutamatergic transmission by ethanol in the developing neocortex: an in vitro test of the excessive inhibition hypothesis of fetal alcohol spectrum disorder.
Topics: Animals; Animals, Newborn; Biophysics; Calcium; Central Nervous System Depressants; Dizocilpine Maleate; Electric Stimulation; Ethanol; Excitatory Amino Acid Antagonists; Female; GABA Agonists; gamma-Aminobutyric Acid; Gene Expression Regulation, Developmental; Glutamic Acid; In Vitro Techniques; K Cl- Cotransporters; Male; Membrane Potentials; Muscimol; Neocortex; Patch-Clamp Techniques; Pregnancy; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Symporters; Synaptic Transmission | 2009 |
GABA and opioid mechanisms of the central amygdala underlie the withdrawal-potentiated startle from acute morphine.
Topics: Amygdala; Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; GABA Agonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Microinjections; Morphine; Motor Activity; Muscimol; Narcotics; Rats; Rats, Wistar; Receptors, Opioid; Receptors, Opioid, mu; Reflex, Startle; Substance Withdrawal Syndrome | 2009 |
Enhancement of inhibitory synaptic transmission in large aspiny neurons after transient cerebral ischemia.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Biophysics; Biotin; Calcium; Choline O-Acetyltransferase; Corpus Striatum; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; In Vitro Techniques; Ion Channel Gating; Ischemic Attack, Transient; Male; Membrane Potentials; Muscimol; Neurons; Ovulation Inhibition; Patch-Clamp Techniques; Rats; Rats, Wistar; Sodium Channel Blockers; Synaptic Transmission; Tetrodotoxin; Time Factors | 2009 |
Localization of the brainstem GABAergic neurons controlling paradoxical (REM) sleep.
Topics: Animals; Brain Stem; Disorders of Excessive Somnolence; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Male; Muscimol; Neurons; Perfusion; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sleep Deprivation; Sleep, REM | 2009 |
GABA expression in the mammalian taste bud functions as a route of inhibitory cell-to-cell communication.
Topics: Animals; Cell Communication; Chloride Channels; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamate Decarboxylase; Ion Channel Gating; Muscimol; Potassium Channels; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Reverse Transcriptase Polymerase Chain Reaction; Taste Buds | 2009 |
Endogenous gamma-aminobutyric acid modulates tonic guinea pig airway tone and propofol-induced airway smooth muscle relaxation.
Topics: Acetylcholine; Anesthetics, Intravenous; Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Immunohistochemistry; Male; Models, Animal; Muscimol; Muscle Relaxation; Muscle, Smooth; Propofol; Pyridazines; Random Allocation; Substance P; Trachea | 2009 |
Transient oligemia is associated with long-term changes in binding densities of cortical inhibitory GABAA receptors in the rat brain.
Topics: Animals; Binding, Competitive; Cerebral Cortex; Disease Models, Animal; Down-Regulation; GABA Agonists; gamma-Aminobutyric Acid; Hippocampus; Hypoxia-Ischemia, Brain; Male; Memory Disorders; Microtubule-Associated Proteins; Muscimol; Parietal Lobe; Radioligand Assay; Rats; Rats, Wistar; Receptors, AMPA; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Time; Time Factors; Tritium | 2009 |
Zero net flux estimates of septal extracellular glucose levels and the effects of glucose on septal extracellular GABA levels.
Topics: Animals; Extracellular Space; gamma-Aminobutyric Acid; Glucose; Hippocampus; Male; Microdialysis; Muscimol; Rats; Rats, Sprague-Dawley; Septum of Brain | 2009 |
Depolarizing GABAergic synaptic input triggers endocannabinoid-mediated retrograde synaptic signaling.
Topics: Aniline Compounds; Animals; Animals, Newborn; Arachidonic Acids; Benzamides; Bicuculline; Biophysics; Calcium; Calcium Signaling; Cannabinoid Receptor Antagonists; Cannabinoid Receptor Modulators; Carbamates; Cerebellum; Electric Stimulation; Endocannabinoids; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fluoresceins; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycerides; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Lactones; Mice; Muscimol; Orlistat; Patch-Clamp Techniques; Piperidines; Purkinje Cells; Pyrazoles; Quinoxalines; Rimonabant; Signal Transduction; Synapses; Valine | 2009 |
KCC2 expression promotes the termination of cortical interneuron migration in a voltage-sensitive calcium-dependent manner.
Topics: Age Factors; Animals; Animals, Newborn; Bicuculline; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Movement; Cerebral Cortex; Electroporation; Embryo, Mammalian; Female; GABA Agents; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamic Acid; Green Fluorescent Proteins; Homeodomain Proteins; Interneurons; K Cl- Cotransporters; LIM-Homeodomain Proteins; Membrane Potentials; Mice; Mice, Inbred BALB C; Mice, Transgenic; Microtubule-Associated Proteins; Models, Biological; Muscimol; Nerve Tissue Proteins; Nifedipine; omega-Conotoxin GVIA; Organ Culture Techniques; Pregnancy; Quinoxalines; Receptors, N-Methyl-D-Aspartate; RNA, Small Interfering; Sequence Deletion; Symporters; Transcription Factors; Valine | 2009 |
The GABA(A) receptor-mediated inhibitory pathway increases the correlated activities in retinal ganglion cells.
Topics: Action Potentials; Animals; Bicuculline; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Mice; Muscimol; Phosphinic Acids; Pyridines; Receptors, GABA-A; Retina; Retinal Ganglion Cells | 2009 |
A fragile balance: perturbation of GABA mediated circuit in prefrontal cortex generates high intraindividual performance variability.
Topics: Animals; Bicuculline; Chlorocebus aethiops; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Prefrontal Cortex; Saccades; Task Performance and Analysis | 2009 |
Pharmacological characterization of harmaline-induced tremor activity in mice.
Topics: Affect; Animals; Anticonvulsants; Baclofen; Behavior, Animal; Benzazepines; Carbolines; Chlordiazepoxide; Dopamine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Harmaline; Lithium Chloride; Male; Mice; Mice, Inbred ICR; Muscimol; Neurotransmitter Agents; Piperazines; Propranolol; Raclopride; Receptors, Glutamate; Sodium Oxybate; Tremor | 2009 |
Effects of chronic manganese exposure on glutamatergic and GABAergic neurotransmitter markers in the nonhuman primate brain.
Topics: Animals; Astrocytes; Autoradiography; Biomarkers; Brain Chemistry; Chromatography, High Pressure Liquid; GABA Agonists; gamma-Aminobutyric Acid; Globus Pallidus; Glutamic Acid; Glycine; Immunohistochemistry; Macaca fascicularis; Male; Manganese Poisoning; Muscimol; Neurotransmitter Agents; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Spectrometry, Fluorescence; Synapses | 2009 |
GABA in pedunculopontine tegmentum increases rapid eye movement sleep in freely moving rats: possible role of GABA-ergic inputs from substantia nigra pars reticulata.
Topics: Animals; Electric Stimulation; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Muscimol; Neural Pathways; Picrotoxin; Rats; Rats, Wistar; Sleep, REM; Substantia Nigra; Tegmentum Mesencephali; Wakefulness | 2009 |
Functional masking of deprived eye responses by callosal input during ocular dominance plasticity.
Topics: Action Potentials; Age Factors; Analysis of Variance; Animals; Animals, Newborn; Chi-Square Distribution; Cholera Toxin; Corpus Callosum; Critical Period, Psychological; Dominance, Ocular; Dose-Response Relationship, Drug; GABA Agonists; gamma-Aminobutyric Acid; Models, Neurological; Muscimol; Neuronal Plasticity; Neurons; Photic Stimulation; Rats; Rats, Long-Evans; Sensory Deprivation; Visual Cortex; Visual Pathways | 2009 |
Comparison of the antiepileptic properties of transmeningeally delivered muscimol, lidocaine, midazolam, pentobarbital and GABA, in rats.
Topics: Acetylcholine; Animals; Anticonvulsants; Electrodes, Implanted; Electroencephalography; gamma-Aminobutyric Acid; Lidocaine; Midazolam; Muscimol; Pentobarbital; Rats; Seizures; Somatosensory Cortex; Time Factors | 2010 |
Basolateral amygdala modulates terminal dopamine release in the nucleus accumbens and conditioned responding.
Topics: Amygdala; Animals; Baclofen; Conditioning, Operant; Data Interpretation, Statistical; Dopamine; Electrochemistry; GABA Agonists; gamma-Aminobutyric Acid; Male; Microinjections; Muscimol; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Signal Transduction; Ventral Tegmental Area | 2010 |
Distinct activities of GABA agonists at synaptic- and extrasynaptic-type GABAA receptors.
Topics: Animals; Cell Line; Dose-Response Relationship, Drug; Electrophysiological Phenomena; Fibroblasts; GABA Agonists; gamma-Aminobutyric Acid; Humans; Hydrogen-Ion Concentration; Isoxazoles; Kidney; Mice; Muscimol; Patch-Clamp Techniques; Receptors, GABA-A; Synapses; Transfection | 2010 |
An UNC-49 GABA receptor subunit from the parasitic nematode Haemonchus contortus is associated with enhanced GABA sensitivity in nematode heteromeric channels.
Topics: Amino Acid Sequence; Animals; Chloride Channels; Cloning, Molecular; Electrophysiology; GABA Agonists; gamma-Aminobutyric Acid; Haemonchus; Helminth Proteins; Ion Channel Gating; Ion Channels; Molecular Sequence Data; Muscimol; Oocytes; Patch-Clamp Techniques; Receptors, GABA; Synaptic Transmission; Xenopus laevis | 2010 |
GABAergic regulation of the perifornical-lateral hypothalamic neurons during non-rapid eye movement sleep in rats.
Topics: Action Potentials; Animals; Bicuculline; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hypothalamic Area, Lateral; Male; Muscimol; Neural Inhibition; Neural Pathways; Neurons; Rats; Rats, Sprague-Dawley; Sleep; Wakefulness | 2010 |
Developmental regulation and neuroprotective effects of striatal tonic GABAA currents.
Topics: Animals; Cell Size; Corpus Striatum; Cytoprotection; Excitatory Amino Acid Agonists; GABA Agonists; gamma-Aminobutyric Acid; Male; Mice; Mice, Knockout; Mice, Transgenic; Muscimol; N-Methylaspartate; Neurons; Neurotoxins; Organ Culture Techniques; Protein Subunits; Receptors, GABA-A | 2010 |
Zolpidem modulation of phasic and tonic GABA currents in the rat dorsal motor nucleus of the vagus.
Topics: Action Potentials; Animals; Brain Stem; GABA Agonists; GABA Uptake Inhibitors; gamma-Aminobutyric Acid; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Miniature Postsynaptic Potentials; Motor Neurons; Muscimol; Nipecotic Acids; Patch-Clamp Techniques; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Vagus Nerve; Zolpidem | 2010 |
Opioidergic and GABAergic mechanisms in the rostral ventromedial medulla modulate the nociceptive response of vocalization in guinea pigs.
Topics: Analgesics, Opioid; Animals; Bicuculline; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Male; Medulla Oblongata; Morphine; Muscimol; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Vocalization, Animal | 2010 |
Modulation of somatosensory-evoked cortical blood flow changes by GABAergic inhibition of the nucleus basalis of Meynert in urethane-anaesthetized rats.
Topics: Anesthesia, General; Anesthetics, Intravenous; Animals; Basal Nucleus of Meynert; Blood Flow Velocity; Cerebrovascular Circulation; Evoked Potentials, Somatosensory; GABA Agonists; gamma-Aminobutyric Acid; Hindlimb; Laser-Doppler Flowmetry; Male; Muscimol; Neural Inhibition; Physical Stimulation; Rats; Rats, Wistar; Regional Blood Flow; Somatosensory Cortex; Time Factors; Ultrasonography, Doppler, Transcranial; Urethane | 2010 |
GABA modulates development of cerebellar Purkinje cell dendrites under control of endocannabinoid signaling.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cannabinoid Receptor Modulators; Cell Movement; Cells, Cultured; Dendrites; Endocannabinoids; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Interneurons; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Muscimol; Purkinje Cells; Receptors, GABA-A; Signal Transduction; Time Factors | 2010 |
Desire and dread from the nucleus accumbens: cortical glutamate and subcortical GABA differentially generate motivation and hedonic impact in the rat.
Topics: Animals; Fear; Feeding Behavior; gamma-Aminobutyric Acid; Glutamic Acid; Motivation; Muscimol; Nucleus Accumbens; Quinoxalines; Rats | 2010 |
GABA(A) receptors in the pontine reticular formation of C57BL/6J mouse modulate neurochemical, electrographic, and behavioral phenotypes of wakefulness.
Topics: Animals; Behavior, Animal; Bicuculline; Electroencephalography; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred C57BL; Microdialysis; Microinjections; Muscimol; Phenotype; Pons; Receptors, GABA-A; Reticular Formation; Wakefulness | 2010 |
Involvement of GABAergic transmission in the midbrain ventral tegmental area in the regulation of hippocampal theta rhythm.
Topics: Animals; Baclofen; Bicuculline; Electroencephalography; Fourier Analysis; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Male; Muscimol; Rats; Rats, Wistar; Theta Rhythm; Ventral Tegmental Area | 2010 |
Neural mechanisms mediating circadian phase resetting by activation of 5-HT(7) receptors in the dorsal raphe: roles of GABAergic and glutamatergic neurotransmission.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Bicuculline; Circadian Rhythm; Cricetinae; Dizocilpine Maleate; Drug Administration Schedule; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Mesocricetus; Microinjections; Muscimol; N-Methylaspartate; Raphe Nuclei; Receptors, Serotonin; Serotonin Receptor Agonists; Synaptic Transmission | 2010 |
GABAergic regulation of auditory sensory gating in low- and high-anxiety rats submitted to a fear conditioning procedure.
Topics: Acoustic Stimulation; Animals; Anxiety; Behavior, Animal; Benzodiazepines; Bicuculline; Clonixin; Conditioning, Classical; Diazepam; Disease Models, Animal; Electroencephalography; Evoked Potentials, Auditory; Fear; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Inferior Colliculi; Male; Maze Learning; Microinjections; Muscimol; Neurons; Prostaglandin Antagonists; Rats; Rats, Wistar; Sensory Gating; Statistics as Topic | 2010 |
An abrupt developmental shift in callosal modulation of sleep-related spindle bursts coincides with the emergence of excitatory-inhibitory balance and a reduction of somatosensory cortical plasticity.
Topics: Age Factors; Animals; Animals, Newborn; Bicuculline; Corpus Callosum; Electroencephalography; Evoked Potentials, Somatosensory; Female; gamma-Aminobutyric Acid; Glutamic Acid; K Cl- Cotransporters; Male; Muscimol; Neural Inhibition; Neuronal Plasticity; Presynaptic Terminals; Rats; Recovery of Function; Sleep; Somatosensory Cortex; Symporters | 2010 |
GABAA receptors in VTA mediate the morphine-induced release of ascorbic acid in rat nucleus accumbens.
Topics: Analgesics, Opioid; Animals; Ascorbic Acid; Bicuculline; Chromatography, High Pressure Liquid; Dopamine; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Microinjections; Morphine; Muscimol; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Ventral Tegmental Area | 2011 |
Astrocytes are GABAergic cells that modulate microglial activity.
Topics: 4-Aminobutyrate Transaminase; Aged; Aged, 80 and over; Annexins; Astrocytes; Blotting, Western; Brain; Cells, Cultured; Cyclohexanecarboxylic Acids; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Immunohistochemistry; Interleukin-6; Male; Microglia; Muscimol; Protozoan Proteins; Receptors, GABA; Reverse Transcriptase Polymerase Chain Reaction; Tumor Necrosis Factor-alpha; Vigabatrin | 2011 |
Inhibitory plasticity underlies visual deprivation-induced loss of receptive field refinement in the adult superior colliculus.
Topics: Animals; Cricetinae; Electrophysiology; GABA Antagonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Mesocricetus; Muscimol; Neuronal Plasticity; Photic Stimulation; Pyridazines; Receptors, GABA-A; Sensory Deprivation; Superior Colliculi; Visual Cortex; Visual Fields; Visual Pathways; Visual Perception | 2011 |
Amygdala regulates risk of predation in rats foraging in a dynamic fear environment.
Topics: Amygdala; Animals; Behavior, Animal; Bicuculline; Environment; Fear; Feeding Behavior; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Muscimol; Predatory Behavior; Rats; Rats, Long-Evans | 2010 |
Development of asymmetric inhibition underlying direction selectivity in the retina.
Topics: Action Potentials; Amacrine Cells; Animals; Dendrites; Electric Conductivity; gamma-Aminobutyric Acid; Mice; Mice, Transgenic; Models, Neurological; Motion; Motion Perception; Muscimol; Neural Inhibition; Neuronal Plasticity; Patch-Clamp Techniques; Photic Stimulation; Pyridazines; Retina; Retinal Ganglion Cells; Synapses | 2011 |
Non-cell-autonomous factor induces the transition from excitatory to inhibitory GABA signaling in retina independent of activity.
Topics: Animals; Cells, Cultured; Coculture Techniques; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Mice; Mice, Knockout; Muscimol; Retinal Ganglion Cells; Signal Transduction; Superior Colliculi | 2010 |
Increased GABAergic inhibition in the midline thalamus affects signaling and seizure spread in the hippocampus-prefrontal cortex pathway.
Topics: Animals; Electric Stimulation; Electroencephalography; Epilepsy, Temporal Lobe; Evoked Potentials; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Hippocampus; Limbic System; Male; Muscimol; Nerve Net; Neural Inhibition; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Seizures; Signal Processing, Computer-Assisted; Signal Transduction; Synapses; Thalamus | 2011 |
Possible involvement of GABAergic mechanism in protective effect of melatonin against sleep deprivation-induced behavior modification and oxidative damage in mice.
Topics: Animals; Antioxidants; Anxiety; Behavior, Animal; Flumazenil; GABA Modulators; gamma-Aminobutyric Acid; Lipid Peroxidation; Male; Melatonin; Mice; Motor Activity; Muscimol; Oxidative Stress; Picrotoxin; Sleep Deprivation | 2011 |
Changes in vasopressin release and autonomic function induced by manipulating forebrain GABAergic signaling under euvolemia and hypovolemia in conscious rats.
Topics: Animals; Arginine Vasopressin; Bicuculline; Blood Pressure; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Heart Rate; Hypovolemia; Male; Muscimol; Rats; Rats, Wistar; Third Ventricle | 2011 |
Novel protective effect of mifepristone on detrimental GABAA receptor activity to immature Purkinje neurons.
Topics: Animals; Caffeine; Chlorides; gamma-Aminobutyric Acid; Imidazoles; Mice; Mifepristone; Muscimol; p38 Mitogen-Activated Protein Kinases; Purkinje Cells; Pyrimidines; Receptors, GABA-A | 2011 |
[The influence of GABAA receptor on the analgesic action of intrathecally injected oxysophoridine].
Topics: Alkaloids; Analgesics; Animals; Bicuculline; Female; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Injections, Spinal; Male; Mice; Muscimol; Pain Threshold; Picrotoxin; Random Allocation; Receptors, GABA-A; Spinal Cord | 2011 |
GABAergic signaling in primary lens epithelial and lentoid cells and its involvement in intracellular Ca2+ modulation.
Topics: Action Potentials; Animals; Animals, Newborn; Baclofen; Bicuculline; Calcium; Calcium Channels; Calcium Signaling; Cell Differentiation; Epithelial Cells; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Lens, Crystalline; Mice; Muscimol; Primary Cell Culture; Receptors, GABA-A; Receptors, GABA-B | 2011 |
Behavioral and EEG effects of GABAergic manipulation of the nigrotectal pathway in the Wistar audiogenic rat strain.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Bicuculline; Corpus Striatum; Electroencephalography; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Muscimol; Neural Pathways; Rats; Rats, Wistar; Seizures; Substantia Nigra; Superior Colliculi; Video Recording | 2011 |
Role of brainstem GABAergic signaling in central cannabinoid receptor evoked sympathoexcitation and pressor responses in conscious rats.
Topics: Analysis of Variance; Animals; Benzoxazines; Blood Pressure; Brain Stem; Dose-Response Relationship, Drug; Drug Interactions; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Heart Rate; Injections, Intraventricular; Male; Morpholines; Muscimol; Naphthalenes; Neurons; Norepinephrine; Piperidines; Proto-Oncogene Proteins c-fos; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Tyrosine 3-Monooxygenase; Wakefulness | 2011 |
The depolarizing action of GABA in cultured hippocampal neurons is not due to the absence of ketone bodies.
Topics: 3-Hydroxybutyric Acid; Action Potentials; Animals; Calcium; Cells, Cultured; Female; gamma-Aminobutyric Acid; Hippocampus; Ketone Bodies; Male; Muscimol; Neurons; Rats; Rats, Long-Evans | 2011 |
In vivo neurochemical evidence that newly synthesised GABA activates GABA(B), but not GABA(A), receptors on dopaminergic nerve endings in the nucleus accumbens of freely moving rats.
Topics: Allylglycine; Animals; Baclofen; Dopamine; Dopaminergic Neurons; Dose-Response Relationship, Drug; GABA Antagonists; GABA-A Receptor Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Male; Microdialysis; Muscimol; Nerve Endings; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B | 2012 |
Pharmacology of intracisternal or intrathecal glycine, muscimol, and baclofen in strychnine-induced thermal hyperalgesia of mice.
Topics: Animals; Baclofen; Drug Delivery Systems; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Hot Temperature; Hyperalgesia; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Muscimol; Pain Threshold; Random Allocation; Strychnine | 2011 |
GABAergic synaptic plasticity during a developmentally regulated sleep-like state in C. elegans.
Topics: Adjuvants, Anesthesia; Aldicarb; Animals; Animals, Genetically Modified; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cholinesterase Inhibitors; Epidermal Growth Factor; GABA Antagonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Green Fluorescent Proteins; Larva; Muscimol; Muscle Contraction; Mutation; Neuromuscular Junction; Pentylenetetrazole; RNA Interference; Sleep; Sodium Oxybate; Time Factors; Transcription Factors; Tretinoin | 2011 |
Peripheral and spinal GABAergic regulation of incisional pain in rats.
Topics: Animals; Baclofen; Behavior, Animal; Chronic Pain; gamma-Aminobutyric Acid; Hyperalgesia; Muscimol; Pain Measurement; Rats; Rats, Sprague-Dawley; Spinal Cord | 2012 |
Analysis of GABA-induced inhibition of spontaneous firing in chick accessory lobe neurons.
Topics: Animals; Bicuculline; Chick Embryo; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Muscimol; Neurons; Spinal Cord | 2012 |
Transition to seizure: ictal discharge is preceded by exhausted presynaptic GABA release in the hippocampal CA3 region.
Topics: Animals; CA3 Region, Hippocampal; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Inhibitory Postsynaptic Potentials; Male; Mice; Mice, Inbred C57BL; Muscimol; Presynaptic Terminals; Seizures | 2012 |
Involvement of hypothalamic periventricular GABAergic nerves in the central pressor response to clonidine in freely-moving conscious rats.
Topics: Animals; Antihypertensive Agents; Baclofen; Bicuculline; Blood Pressure; Clonidine; Excitatory Amino Acid Antagonists; GABA Agents; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; GABAergic Neurons; gamma-Aminobutyric Acid; Heart Rate; Hypothalamus; Kynurenic Acid; Male; Muscimol; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Receptors, Glutamate | 2012 |
GABAergic processes within the median preoptic nucleus promote NREM sleep.
Topics: Animals; Bicuculline; Cats; Data Interpretation, Statistical; Electroencephalography; Electromyography; GABA Agents; GABA Agonists; GABA Antagonists; GABAergic Neurons; gamma-Aminobutyric Acid; Immunohistochemistry; Male; Microinjections; Muscimol; Preoptic Area; Sleep; Sleep, REM; Wakefulness | 2012 |
Oxysophoridine through intrathecal injection induces antinociception and increases the expression of the GABAAα1 receptor in the spinal cord of mice.
Topics: Alkaloids; Analgesics; Animals; Bicuculline; Drug Evaluation, Preclinical; Drug Interactions; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Injections, Spinal; Mice; Mice, Inbred ICR; Muscimol; Pain Measurement; Picrotoxin; Receptors, GABA-A; Spinal Cord | 2012 |
Behavioral and EEG effects of GABAergic manipulation of the nigro-tectal pathway in the Wistar audiogenic rat (WAR) strain II: an EEG wavelet analysis and retrograde neuronal tracer approach.
Topics: Acoustic Stimulation; Animals; Behavior, Animal; Bicuculline; Brain Waves; Disease Models, Animal; Electric Stimulation; Epilepsy, Reflex; GABA Agents; gamma-Aminobutyric Acid; Male; Microinjections; Muscimol; Neural Pathways; Rats; Rats, Mutant Strains; Rats, Wistar; Stilbamidines; Substantia Nigra; Superior Colliculi | 2012 |
Possible interaction of cholinergic and GABAergic systems between MS and CA1 upon memory acquisition in rats.
Topics: Analysis of Variance; Animals; Avoidance Learning; Bicuculline; CA1 Region, Hippocampal; Cholinergic Agents; Cholinergic Antagonists; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Memory; Mental Recall; Motor Activity; Muscimol; Neural Pathways; Physostigmine; Rats; Rats, Wistar; Reaction Time; Scopolamine; Septum of Brain | 2012 |
Recurrent interactions between the input and output of a songbird cortico-basal ganglia pathway are implicated in vocal sequence variability.
Topics: Action Potentials; Anesthetics, Local; Animals; Bicuculline; Biophysics; Cell Count; Cerebral Cortex; Dopamine beta-Hydroxylase; Dopaminergic Neurons; Electric Stimulation; Functional Laterality; GABA Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; High Vocal Center; Ibotenic Acid; Lidocaine; Luminescent Agents; Male; Microdialysis; Muscimol; Neural Pathways; Songbirds; Statistics, Nonparametric; Tyrosine 3-Monooxygenase; Vocalization, Animal | 2012 |
GABA and glutamate receptors have different effects on excitability and are differentially regulated by calcium in spider mechanosensory neurons.
Topics: Animals; Calcium; Calcium Signaling; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Insect Proteins; Mechanoreceptors; Membrane Potentials; Muscimol; Neurons, Efferent; Phosphorylation; Receptors, GABA-A; Receptors, Glutamate; Sensilla; Spiders | 2012 |
Hco-LGC-38 is novel nematode cys-loop GABA receptor subunit.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cloning, Molecular; Dieldrin; Electrophysiology; gamma-Aminobutyric Acid; Haemonchus; Helminth Proteins; Ligand-Gated Ion Channels; Models, Molecular; Molecular Sequence Data; Muscimol; Phylogeny; Receptors, GABA; Sequence Analysis, DNA; Xenopus laevis | 2012 |
Effects of mood stabilizers on marble-burying behavior in mice: involvement of GABAergic system.
Topics: Animals; Antipsychotic Agents; Baclofen; Behavior, Animal; Bicuculline; Carbamazepine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Lamotrigine; Lithium Carbonate; Male; Mice; Mice, Inbred ICR; Motor Activity; Muscimol; Obsessive-Compulsive Disorder; Receptors, GABA-A; Triazines; Valproic Acid | 2013 |
Effects of oxymatrine on the neuropathic pain induced by chronic constriction injury in mice.
Topics: Alkaloids; Animals; Chronic Disease; Constriction; Disease Models, Animal; Dose-Response Relationship, Drug; GABA Antagonists; GABA Plasma Membrane Transport Proteins; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Gene Expression Regulation; Male; Mice; Mice, Inbred ICR; Muscimol; Neuralgia; Neuroprotective Agents; Nipecotic Acids; Oximes; Pain Measurement; Pain Threshold; Quinolizines; Receptors, GABA-A; Spinal Cord | 2012 |
Blunted endogenous GABA-mediated inhibition in the hypothalamic paraventricular nucleus of rats with streptozotocin-induced diabetes.
Topics: Animals; Bicuculline; Blood Pressure; Diabetes Mellitus, Experimental; Disease Models, Animal; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Heart Rate; Male; Microinjections; Muscimol; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Streptozocin | 2013 |
GABAergic synaptic inputs of locus coeruleus neurons in wild-type and Mecp2-null mice.
Topics: Animals; Baclofen; Female; GABA Antagonists; GABA-A Receptor Agonists; GABA-B Receptor Agonists; GABAergic Neurons; gamma-Aminobutyric Acid; Humans; Locus Coeruleus; Male; Membrane Potentials; Methyl-CpG-Binding Protein 2; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscimol; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; Presynaptic Terminals; Receptors, GABA-A; Receptors, GABA-B; Rett Syndrome; Synaptic Membranes; Synaptic Transmission | 2013 |
Ventral tegmental area GABA neurons and opiate motivation.
Topics: Acetazolamide; Analgesics, Opioid; Animals; Electrophysiology; Furosemide; gamma-Aminobutyric Acid; Gene Knock-In Techniques; Male; Mice; Morphine; Motivation; Muscimol; Neurons; Rats; Rats, Wistar; Receptors, GABA-A; Ventral Tegmental Area | 2013 |
Excitatory actions of GABA in developing chick vestibular afferents: effects on resting electrical activity.
Topics: Action Potentials; Animals; Chick Embryo; Chloride Channels; Chlorides; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Muscimol; Neurons, Afferent; Vestibular Nerve | 2013 |
Quantum dot conjugates of GABA and muscimol: binding to α1β2γ2 and ρ1 GABA(A) receptors.
Topics: Animals; Binding Sites; Female; gamma-Aminobutyric Acid; Humans; Muscimol; Protein Binding; Protein Subunits; Quantum Dots; Receptors, GABA-A; Receptors, GABA-B; Xenopus laevis | 2013 |
Further evidence for involvement of the dorsal hippocampus serotonergic and γ-aminobutyric acid (GABA)ergic pathways in the expression of contextual fear conditioning in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Brain; Conditioning, Psychological; Fear; Freezing Reaction, Cataleptic; gamma-Aminobutyric Acid; Hippocampus; Male; Muscimol; Prefrontal Cortex; Rats; Rats, Wistar; Reflex, Startle; Serotonin; Serotonin Receptor Agonists; Time Factors | 2013 |
Changes on auditory physiology in response to the inactivation of amygdala nuclei in high anxiety rats expressing learned fear.
Topics: Amygdala; Animals; Anxiety; Conditioning, Psychological; Evoked Potentials, Auditory; Fear; GABA Agonists; gamma-Aminobutyric Acid; Hearing; Inferior Colliculi; Learning; Male; Microinjections; Muscimol; Rats; Rats, Wistar | 2013 |
Effect of GABA, a bacterial metabolite, on Pseudomonas fluorescens surface properties and cytotoxicity.
Topics: Animals; Bacterial Adhesion; Bicuculline; Biofilms; Cell Death; Diffusion; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Lipopolysaccharides; Muscimol; Neuroglia; Oligopeptides; Pseudomonas fluorescens; Rats; Receptors, GABA-A; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Surface Properties | 2013 |
3,4,5-Trimethoxycinnamic acid (TMCA), one of the constituents of Polygalae Radix enhances pentobarbital-induced sleeping behaviors via GABAAergic systems in mice.
Topics: Animals; Cerebellum; Chlorides; Cinnamates; Drug Synergism; GABA Agonists; GABAergic Neurons; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hypnotics and Sedatives; Male; Mice; Motor Activity; Muscimol; Neurons; Pentobarbital; Polygala; Primary Cell Culture; Receptors, GABA-A; Sleep; Sleep Stages | 2013 |
Focal uncaging of GABA reveals a temporally defined role for GABAergic inhibition during appetitive associative olfactory conditioning in honeybees.
Topics: Animals; Bees; Conditioning, Classical; gamma-Aminobutyric Acid; Memory; Muscimol; Neural Inhibition; Phenylacetates; Receptors, GABA-A; Reward; Smell | 2013 |
Expression of the γ2-subunit distinguishes synaptic and extrasynaptic GABA(A) receptors in NG2 cells of the hippocampus.
Topics: Animals; Benzodiazepines; Bicuculline; Diazepam; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Muscimol; Neuroglia; Neurons; Patch-Clamp Techniques; Pentobarbital; Protein Subunits; Receptors, GABA-A; Synapses | 2013 |
γ-Aminobutyric acid regulates both the survival and replication of human β-cells.
Topics: Animals; Apoptosis; Baclofen; Cell Survival; Diabetes Mellitus, Experimental; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Heterografts; Humans; Insulin-Secreting Cells; Islets of Langerhans Transplantation; Male; Mice; Mice, Inbred NOD; Muscimol; Receptors, GABA-A | 2013 |
Involvement of NMDA receptor in low-frequency magnetic field-induced anxiety in mice.
Topics: Animals; Anxiety; Bicuculline; Brain; Dizocilpine Maleate; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamic Acid; Magnetic Fields; Male; Maze Learning; Mice; Muscimol; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Social Behavior; Time Factors | 2014 |
Glutamate/GABA balance in ACC modulates the nociceptive responses of vocalization: an expression of affective-motivational component of pain in guinea pigs.
Topics: Animals; Bicuculline; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agents; GABA Agents; gamma-Aminobutyric Acid; Glutamic Acid; Guinea Pigs; Gyrus Cinguli; Homocysteine; Male; Microinjections; Muscimol; Pain; Time Factors; Vocalization, Animal | 2014 |
Depolarizing chloride gradient in developing cochlear nucleus neurons: underlying mechanism and implication for calcium signaling.
Topics: Animals; Bumetanide; Calcium Channels; Calcium Signaling; Chlorine; Cochlear Nucleus; Extracellular Space; Female; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Gerbillinae; In Vitro Techniques; Intracellular Space; Male; Membrane Potentials; Models, Neurological; Muscimol; Neurons; Sodium; Sodium Potassium Chloride Symporter Inhibitors; Solute Carrier Family 12, Member 2 | 2014 |
Blunted GABA-mediated inhibition within the dorsomedial hypothalamus potentiates the cardiovascular response to emotional stress in rats fed a high-fat diet.
Topics: Animals; Arterial Pressure; Bicuculline; Diet, High-Fat; Emotions; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Heart Rate; Male; Muscimol; Obesity; Physical Stimulation; Rats; Rats, Wistar; Receptors, GABA-A; Stress, Psychological; Tachycardia; Time Factors | 2014 |
Peripheral GABAA receptor activation modulates rat tongue afferent mechanical sensitivity.
Topics: Administration, Topical; Animals; Benzodiazepines; Burning Mouth Syndrome; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Hot Temperature; Muscimol; Nerve Fibers; Pressure; Rats; Receptors, GABA-A; Tongue; Trigeminal Ganglion | 2014 |
Prefrontal gamma-aminobutyric acid type A receptor insertion controls cue-induced relapse to nicotine seeking.
Topics: Animals; Conditioning, Operant; Cues; Drug-Seeking Behavior; Extinction, Psychological; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Gene Expression Regulation; Male; Muscimol; Nicotine; Peptides; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Glutamate; Recurrence; Self Administration; Synapses; Tobacco Use Disorder | 2014 |
GABAAergic stimulation modulates intracellular protein arginine methylation.
Topics: Animals; Arginine; Bicuculline; Cell Differentiation; Cell Line; Diazepam; Drug Synergism; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Intracellular Space; Methylation; Mice, Knockout; Muscimol; Neurons; Protein-Arginine N-Methyltransferases; Receptors, GABA-A; Signal Transduction | 2014 |
Nociceptive vocalization response in guinea pigs modulated by opioidergic, GABAergic and serotonergic neurotransmission in the dorsal raphe nucleus.
Topics: Analgesics, Opioid; Animals; Bicuculline; Dorsal Raphe Nucleus; GABA Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Male; Morphine; Muscimol; Naloxone; Narcotic Antagonists; Nociception; Serotonin; Synaptic Transmission; Vocalization, Animal | 2014 |
Consequences of gestational stress on GABAergic modulation of respiratory activity in developing newborn pups.
Topics: Animals; Animals, Newborn; Brain Stem; Cervical Vertebrae; Dose-Response Relationship, Drug; Female; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Male; Muscimol; Plethysmography, Whole Body; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation; Rats, Sprague-Dawley; Receptors, GABA-A; Respiration; Sex Characteristics; Spinal Cord; Stress, Psychological; Tissue Culture Techniques | 2014 |
γ-Aminobutyric acid neural signaling in the lateroanterior hypothalamus modulates aggressive behavior in adolescent anabolic/androgenic steroid-treated hamsters.
Topics: Aggression; Anabolic Agents; Androgens; Animals; Behavior, Animal; Bicuculline; Cricetinae; Dose-Response Relationship, Drug; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hypothalamus; Male; Mesocricetus; Muscimol; Receptors, GABA-A; Signal Transduction | 2014 |
Ionotropic GABA and glycine receptor subunit composition in human pluripotent stem cell-derived excitatory cortical neurones.
Topics: Cerebral Cortex; gamma-Aminobutyric Acid; Humans; Muscimol; Neurons; Pluripotent Stem Cells; Protein Subunits; Receptors, GABA-A; Receptors, Glycine | 2014 |
GABA protects pancreatic beta cells against apoptosis by increasing SIRT1 expression and activity.
Topics: Animals; Apoptosis; Baclofen; Cell Line, Tumor; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation; Humans; Insulin-Secreting Cells; Muscimol; NAD; Picrotoxin; Primary Cell Culture; Rats; Receptors, GABA-A; Receptors, GABA-B; Signal Transduction; Sirtuin 1; Transcription Factor RelA | 2014 |
GABA modulation of SVZ-derived progenitor ventral cell migration.
Topics: Animals; Animals, Newborn; Cell Movement; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Mice; Microdissection; Microscopy, Confocal; Muscimol; Neural Stem Cells; Prosencephalon; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; Stem Cell Niche; Tissue Culture Techniques | 2015 |
Medial prefrontal cortex serotonergic and GABAergic mechanisms modulate the expression of contextual fear: intratelencephalic pathways and differential involvement of cortical subregions.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Biotin; Conditioning, Psychological; Dextrans; Fear; Freezing Reaction, Cataleptic; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Limbic Lobe; Male; Muscimol; Neural Pathways; Neuroanatomical Tract-Tracing Techniques; Neuronal Tract-Tracers; Prefrontal Cortex; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, GABA-A; Reflex, Startle; Serotonin; Serotonin 5-HT1 Receptor Agonists | 2015 |
Prefrontal cortical GABA modulation of spatial reference and working memory.
Topics: Animals; Baclofen; Bicuculline; Discrimination, Psychological; GABA Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Maze Learning; Memory, Short-Term; Muscimol; Prefrontal Cortex; Rats, Long-Evans; Receptors, GABA-A; Spatial Memory | 2014 |
The role of the GABA-A receptor of the adjacent intact dorsal root ganglion neurons in rats with neuropathic pain.
Topics: Animals; Biophysics; Cell Size; Cells, Cultured; Disease Models, Animal; Electric Stimulation; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Ganglia, Spinal; Male; Membrane Potentials; Muscimol; Neuralgia; Neurons; Pain Measurement; Pain Threshold; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Time Factors | 2014 |
An evolutionarily conserved switch in response to GABA affects development and behavior of the locomotor circuit of Caenorhabditis elegans.
Topics: Animals; Anion Transport Proteins; Caenorhabditis elegans; Caenorhabditis elegans Proteins; GABA-A Receptor Agonists; GABAergic Neurons; gamma-Aminobutyric Acid; K Cl- Cotransporters; Locomotion; Membrane Potentials; Muscimol; Mutation; Receptors, GABA-A; Solute Carrier Family 12, Member 2; Symporters; Synaptic Transmission | 2015 |
Age- and sex-related characteristics of tonic GABA currents in the rat substantia nigra pars reticulata.
Topics: Age Factors; Animals; Female; gamma-Aminobutyric Acid; Male; Muscimol; Pyridines; Rats; Rats, Sprague-Dawley; Sex Factors; Substantia Nigra; Zolpidem | 2015 |
[Behavior of high- and low-anxiety rats after modulation of GABAergic transmission in basolateral amygdala].
Topics: Aggression; Animals; Anxiety; Basolateral Nuclear Complex; Bicuculline; Functional Laterality; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Injections, Intraventricular; Locomotion; Male; Maze Learning; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A; Severity of Illness Index; Synaptic Transmission | 2014 |
Involvement of medullary GABAergic system in extraterritorial neuropathic pain mechanisms associated with inferior alveolar nerve transection.
Topics: Acetates; Action Potentials; Animals; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Hyperalgesia; Indenes; Mandibular Nerve; Medulla Oblongata; Muscimol; Neurons; Pain Threshold; Physical Stimulation; Rats; Rats, Transgenic; Time; Trigeminal Nerve Injuries; Vesicular Inhibitory Amino Acid Transport Proteins | 2015 |
Regional modulation of the response to glutathione in Hydra vulgaris.
Topics: Animals; Feeding Behavior; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutathione; Glycine; Hydra; Muscimol; Receptors, GABA; Receptors, Glycine; Strychnine | 2015 |
GABA-Mediated Inactivation of Medial Prefrontal and Agranular Insular Cortex in the Rat: Contrasting Effects on Hunger- and Palatability-Driven Feeding.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cerebral Cortex; Drinking; Eating; Excitatory Amino Acid Antagonists; Exploratory Behavior; Feeding Behavior; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Hunger; Male; Muscimol; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Taste | 2016 |
GABA signalling modulates plant growth by directly regulating the activity of plant-specific anion transporters.
Topics: Acidosis; Aluminum; Amino Acid Motifs; Animals; Arabidopsis; Bicuculline; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hordeum; Membrane Potentials; Microscopy, Confocal; Muscimol; Mutagenesis, Site-Directed; Nicotiana; Oocytes; Organic Anion Transporters; Patch-Clamp Techniques; Plant Proteins; Pollen Tube; Signal Transduction; Stress, Physiological; Triticum; Vitis; Xenopus laevis | 2015 |
GABA modulates baroreflex in the ventral tegmental area in rat.
Topics: Animals; Baclofen; Baroreflex; Bicuculline; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rats, Wistar; Ventral Tegmental Area | 2015 |
GABA-induced inactivation of dorsal midline thalamic subregions has distinct effects on emotional behaviors.
Topics: Animals; Baclofen; Emotions; Exploratory Behavior; GABA-A Receptor Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Male; Maze Learning; Microinjections; Midline Thalamic Nuclei; Motor Activity; Muscimol; Rats, Long-Evans | 2015 |
Opposing Roles of Cholinergic and GABAergic Activity in the Insular Cortex and Nucleus Basalis Magnocellularis during Novel Recognition and Familiar Taste Memory Retrieval.
Topics: Acetylcholine; Animals; Basal Nucleus of Meynert; Bicuculline; Cerebral Cortex; Drinking Behavior; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Mental Recall; Muscimol; Parasympathetic Nervous System; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Recognition, Psychology; Taste Perception | 2016 |
Ghrelin activates hypophysiotropic corticotropin-releasing factor neurons independently of the arcuate nucleus.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Arginine; Corticosterone; Corticotropin-Releasing Hormone; GABA Antagonists; gamma-Aminobutyric Acid; Gene Knockdown Techniques; Ghrelin; Infusions, Intraventricular; Male; Mice; Muscimol; Neurons; Neuropeptide Y; Paraventricular Hypothalamic Nucleus; Receptors, Ghrelin | 2016 |
Chronic Unpredictable Mild Stress Induces Loss of GABA Inhibition in Corticotrophin-Releasing Hormone-Expressing Neurons through NKCC1 Upregulation.
Topics: Animals; Bumetanide; Corticosterone; Corticotropin-Releasing Hormone; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Membrane Potentials; Muscimol; Neural Inhibition; Neurons; Paraventricular Hypothalamic Nucleus; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sodium Potassium Chloride Symporter Inhibitors; Solute Carrier Family 12, Member 2; Stress, Psychological; Up-Regulation | 2017 |
Involvement of glutamatergic N-methyl-d-aspartate receptors in the expression of increased head-dipping behaviors in the hole-board tests of olfactory bulbectomized mice.
Topics: Amygdala; Animals; Anti-Anxiety Agents; Anxiety; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Exploratory Behavior; Frontal Lobe; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Head Movements; Male; Mice; Mice, Inbred ICR; Motor Activity; Muscimol; Olfactory Bulb; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate | 2016 |
Suppressed GABAergic signaling in the zona incerta causes neuropathic pain in a thoracic hemisection spinal cord injury rat model.
Topics: Action Potentials; Animals; Bicuculline; GABA Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Neuralgia; Neurons; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Signal Transduction; Spinal Cord Injuries; Zona Incerta | 2016 |
Acute spinal cord injury (SCI) transforms how GABA affects nociceptive sensitization.
Topics: Acetates; Analysis of Variance; Animals; Bicuculline; Bumetanide; Capsaicin; Disease Models, Animal; GABA Agents; gamma-Aminobutyric Acid; Gene Expression Regulation; Hyperalgesia; Indenes; K Cl- Cotransporters; Lipopolysaccharides; Male; MAP Kinase Signaling System; Muscimol; Nociception; Pain Measurement; Physical Stimulation; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium Potassium Chloride Symporter Inhibitors; Spinal Cord Injuries; Symporters; Time Factors | 2016 |
Effects of GABA, Neural Regulation, and Intrinsic Cardiac Factors on Heart Rate Variability in Zebrafish Larvae.
Topics: Acetylcholine; Animals; Bicuculline; Caffeine; Central Nervous System Depressants; Central Nervous System Stimulants; Cholinergic Agonists; Dopamine; Dopamine Agents; Ethanol; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation, Developmental; Heart; Heart Rate; Larva; Lidocaine; Methacholine Chloride; Muscarinic Agonists; Muscimol; Zebrafish | 2017 |
Protective roles of hepatic GABA signaling in acute liver injury of rats.
Topics: Animals; Baclofen; Chemical and Drug Induced Liver Injury; GABA-A Receptor Agonists; GABA-B Receptor Agonists; Galactosamine; gamma-Aminobutyric Acid; Hep G2 Cells; Hepatocytes; Humans; Liver; Male; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2017 |
Reduced GABAergic transmission in the ventrobasal thalamus contributes to thermal hyperalgesia in chronic inflammatory pain.
Topics: Animals; Chronic Pain; Extracellular Space; Freund's Adjuvant; GABAergic Neurons; gamma-Aminobutyric Acid; Gene Knockout Techniques; Hyperalgesia; Inflammation; Isoxazoles; Male; Muscimol; Optogenetics; Patch-Clamp Techniques; Protein Subunits; Rats, Sprague-Dawley; Receptors, GABA-A; Synaptic Transmission; Thalamus | 2017 |
Paracrine GABA and insulin regulate pancreatic alpha cell proliferation in a mouse model of type 1 diabetes.
Topics: Animals; Blood Glucose; Cell Proliferation; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Glucagon; Glucagon-Secreting Cells; Male; Mice; Mice, Inbred C57BL; Muscimol | 2017 |
Postpartum estrogen withdrawal impairs GABAergic inhibition and LTD induction in basolateral amygdala complex via down-regulation of GPR30.
Topics: Animals; Basolateral Nuclear Complex; Contraceptive Agents; Down-Regulation; Estradiol; Estrogens; Evoked Potentials; Female; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Long-Term Synaptic Depression; Mice; Mice, Inbred ICR; Muscimol; Ovariectomy; Postpartum Period; Progesterone; Progestins; Receptors, Estrogen; Receptors, G-Protein-Coupled; Signal Transduction; Substance Withdrawal Syndrome | 2017 |
Selective inhibition of extra-synaptic α5-GABA
Topics: Animals; Benzodiazepines; Binding, Competitive; Brain; Female; Flumazenil; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; HEK293 Cells; Humans; Long-Term Potentiation; Male; Memory; Mice, Inbred C57BL; Muscimol; Neural Inhibition; Nootropic Agents; Oxazoles; Rats, Sprague-Dawley; Receptors, GABA-A; Tissue Culture Techniques | 2017 |
Pharmacological manipulation of GABA activity in nucleus subpretectalis/interstitio-pretecto-subpretectalis (SP/IPS) impairs figure-ground discrimination in pigeons: Running head: SP/IPS in figure-ground segregation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Brain; Columbidae; Discrimination, Psychological; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Muscimol; Neural Inhibition; Receptors, GABA-A; Receptors, Glutamate; Visual Pathways; Visual Perception | 2018 |
GABA-ergic neurotransmission in the nucleus of the solitary tract modulates cough in the cat.
Topics: Animals; Baclofen; Blood Pressure; Cats; Cough; Esophagus; gamma-Aminobutyric Acid; Heart Rate; Inhalation; Male; Muscimol; Neurotransmitter Agents; Receptors, GABA-B; Solitary Nucleus; Synaptic Transmission | 2018 |
GABA is an inhibitory neurotransmitter in the neural circuit regulating metamorphosis in a marine snail.
Topics: Aminooxyacetic Acid; Animals; Anions; Bicuculline; Chlorides; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Larva; Metamorphosis, Biological; Muscimol; Neurotransmitter Agents; Pyridazines; Receptors, GABA-A; Serotonin; Snails | 2018 |
Glycinergic neurotransmission in the rostral ventrolateral medulla controls the time course of baroreflex-mediated sympathoinhibition.
Topics: 4-Aminopyridine; Animals; Baroreflex; Bicuculline; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glycine; Glycine Agents; Inhibitory Postsynaptic Potentials; Male; Medulla Oblongata; Muscimol; Neural Inhibition; Neurons; Potassium Channel Blockers; Rats, Sprague-Dawley; Strychnine; Sympathetic Nervous System; Synaptic Transmission; Tetrodotoxin | 2019 |
GABAergic mediation of hippocampal theta rhythm induced by stimulation of the vagal nerve.
Topics: Animals; Baclofen; Bicuculline; GABA Agonists; GABA Antagonists; GABAergic Neurons; gamma-Aminobutyric Acid; Hippocampus; Male; Muscimol; Neurons; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Theta Rhythm; Vagus Nerve; Vagus Nerve Stimulation | 2019 |
Cytosolic GABA inhibits anion transport by wheat ALMT1.
Topics: Animals; Anions; Cell Membrane; Cytosol; gamma-Aminobutyric Acid; Ion Channel Gating; Ion Transport; Muscimol; Mutation; Oocytes; Plant Proteins; Triticum; Xenopus laevis | 2020 |
GABAergic function in the lateral hypothalamus regulates feeding behavior: Possible mediation via orexin.
Topics: Animals; Bicuculline; Eating; Feeding Behavior; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hypothalamic Area, Lateral; Microdialysis; Muscimol; Orexins | 2019 |
Image-guided neural activity manipulation with a paramagnetic drug.
Topics: Animals; Brain; Brain Waves; Contrast Media; GABA Agonists; gamma-Aminobutyric Acid; Magnetic Resonance Imaging; Male; Muscimol; Rats, Sprague-Dawley | 2020 |
GABA
Topics: gamma-Aminobutyric Acid; Muscimol; Neuroglia; Receptors, GABA-A; White Matter | 2020 |
Dopaminergic Modulation of Orofacial Mechanical Hypersensitivity Induced by Infraorbital Nerve Injury.
Topics: Animals; Cranial Nerves; Dopamine; Extracellular Signal-Regulated MAP Kinases; Facial Nerve Injuries; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Hyperalgesia; Hypothalamus; Male; Muscimol; Neuralgia; Oxidopamine; Pain Measurement; Pain Threshold; Phosphorylation; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine D2; Spinal Cord | 2020 |
GABAergic Transmission in the Basolateral Amygdala Differentially Modulates Plasticity in the Dentate Gyrus and the CA1 Areas.
Topics: Animals; Basolateral Nuclear Complex; CA1 Region, Hippocampal; Dentate Gyrus; Electrodes; gamma-Aminobutyric Acid; Long-Term Potentiation; Male; Muscimol; Neuronal Plasticity; Perforant Pathway; Rats, Sprague-Dawley; Synaptic Transmission | 2020 |
Differential effects of GABA
Topics: Animals; Anxiety; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Male; Microinjections; Muscimol; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, GABA-A; Treatment Outcome | 2020 |
GABA in the medial prefrontal cortex regulates anxiety-like behavior during the postpartum period.
Topics: Animals; Anxiety; Behavior, Animal; Bicuculline; Disease Models, Animal; Female; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABAergic Neurons; gamma-Aminobutyric Acid; Humans; Male; Maternal Deprivation; Muscimol; Prefrontal Cortex; Puerperal Disorders; Rats, Sprague-Dawley | 2021 |
GABA
Topics: Anesthesia; Animals; Basal Forebrain; Electroencephalography; gamma-Aminobutyric Acid; Muscimol; Propofol; Rats; Receptors, GABA-A | 2022 |
Effects of GABAA receptors in nucleus cuneiformis on the cannabinoid antinociception using the formalin test.
Topics: Animals; Benzoxazines; Bicuculline; Cannabinoids; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Morpholines; Muscimol; Naphthalenes; Nociception; Pain; Pain Measurement; Rats; Rats, Wistar; Receptors, GABA-A | 2021 |
Flexible versus Fixed Spatial Self-Ordered Response Sequencing: Effects of Inactivation and Neurochemical Modulation of Ventrolateral Prefrontal Cortex.
Topics: Animals; Antipsychotic Agents; Baclofen; Callithrix; Cognition Disorders; Dopamine; Dopamine D2 Receptor Antagonists; Fluorobenzenes; GABA Agonists; gamma-Aminobutyric Acid; Goals; Memory, Short-Term; Muscimol; Piperidines; Prefrontal Cortex; Psychomotor Performance; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Spatial Behavior; Sulpiride | 2021 |
Delayed but not immediate effects of estrogen curtail gamma-aminobutyric acid-mediated feeding responses elicited from the nucleus accumbens shell.
Topics: Animals; Eating; Estrogens; Feeding Behavior; gamma-Aminobutyric Acid; Male; Muscimol; Nucleus Accumbens; Rats; Rats, Sprague-Dawley | 2022 |
Competitive chrodrimanin B interactions with rat brain GABA
Topics: Animals; Binding, Competitive; Bombyx; Brain; gamma-Aminobutyric Acid; Larva; Muscimol; Polyketides; Rats; Receptors, GABA-A; Sesquiterpenes | 2022 |
Involvement of GABAA receptors of lateral habenula in the acquisition and expression phases of morphine-induced place preference in male rats.
Topics: Animals; Bicuculline; Conditioning, Operant; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Habenula; Male; Morphine; Muscimol; Rats; Rats, Wistar; Receptors, GABA; Receptors, GABA-A | 2022 |
Modulation of cholinergic, GABA-ergic and glutamatergic components of superior colliculus affect REM sleep in rats.
Topics: Animals; Cholinergic Agents; Dizocilpine Maleate; gamma-Aminobutyric Acid; Muscimol; Picrotoxin; Rats; Scopolamine; Sleep, REM; Superior Colliculi; Wakefulness | 2023 |
Effects of bile duct ligation on the inhibitory control of supraoptic vasopressin neurons.
Topics: Animals; Arginine Vasopressin; Bile Ducts; Chlorides; gamma-Aminobutyric Acid; Green Fluorescent Proteins; Hyponatremia; Liver Cirrhosis; Male; Muscimol; Neurons; Rats; Rats, Sprague-Dawley; Supraoptic Nucleus; Vasopressins | 2023 |
Muscimol inhibits plasma membrane rupture and ninjurin-1 oligomerization during pyroptosis.
Topics: Cell Membrane; gamma-Aminobutyric Acid; Gasdermins; Intracellular Signaling Peptides and Proteins; Muscimol; Pyroptosis; Receptors, GABA-A | 2023 |