muscimol has been researched along with flumazenil in 88 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 32 (36.36) | 18.7374 |
1990's | 32 (36.36) | 18.2507 |
2000's | 20 (22.73) | 29.6817 |
2010's | 4 (4.55) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Kukulka, KM; Mans, AM; McAvoy, KJ; Rokosz, NC | 1 |
Inano, S | 1 |
Ohno, M; Watanabe, S; Yamamoto, T | 1 |
Galpern, WR; Greenblatt, DJ; Lumpkin, M; Miller, LG; Shader, RI | 1 |
Ichihara, K; Kameyama, T; Nabeshima, T; Tohyama, K | 2 |
Airaksinen, MM; MacDonald, E; Rägo, L; Saano, V | 1 |
Da-Cunha, C; Ferreira, MB; Izquierdo, I; Jerusalinsky, D; Medina, JH; Wolfman, C | 1 |
Basile, AS | 1 |
Allikmets, L; Lang, A; Soosaar, A; Vasar, E | 1 |
Greenblatt, DJ; Heller, J; Lumpkin, M; Miller, LG; Shader, RI; Weill, CL | 1 |
Giros, B; Llorens-Cortes, C; Quach, TT; Schwartz, JC; Van Amsterdam, JG | 1 |
Da Cunha, C; Huang, CH; Izquierdo, I; Medina, JH; Walz, R; Wolfman, C | 1 |
Greenblatt, DJ; Miller, LG; Roy, RB; Shader, RI; Summer, WR | 1 |
Fillenz, M; Pei, Q; Zetterström, T | 1 |
Aosaki, T; Kanai, Y; Manabe, S; Wada, O | 1 |
Canonaco, M; McEwen, BS; O'Connor, LH; Pfaff, DW | 1 |
Crawley, JN; Deutsch, SI; Drugan, RC; Morrow, AL; Paul, SM; Weizman, A; Weizman, R | 1 |
Miller, LG; Roy, RB; Weill, CL | 1 |
Kumasaka, Y; Ueki, S; Yamamoto, T | 1 |
Cox, DH; Guidotti, A; Santi, MR | 1 |
Hanada, S; Hashimoto, S; Tanaka, C; Taniyama, K | 1 |
Kuga, T; Moroi, K; Takashi, K | 1 |
Ennis, C; Minchin, MC | 1 |
Greentree, SG; Pertwee, RG; Swift, PA | 1 |
Basile, AS; Gammal, SH; Jones, EA; Mullen, KD; Skolnick, P | 1 |
Kuriyama, K; Taguchi, J | 1 |
Spealman, RD | 1 |
Fuxe, K; Ogren, SO | 1 |
Karobath, M; Supavilai, P | 1 |
Kempner, ES; Paul, SM; Schwartz, RD; Skolnick, P; Thomas, JW | 1 |
Simmonds, MA | 1 |
Haefely, W; Möhler, H; Richards, JG; Schoch, P | 1 |
Sweetnam, PM; Tallman, JF | 1 |
Allikmets, LKh; Maĭmets, MO; Nurk, AM; Soosaar, AKh; Vasar, EE | 1 |
Goldstein, JM; Malick, JB; Sutton, EB | 1 |
Itoh, Y; Nishibori, M; Oishi, R; Saeki, K | 1 |
Villiger, JW | 1 |
Borea, PA; Karobath, M; Supavilai, P | 1 |
Biggio, G; Concas, A; Salis, M; Serra, M | 1 |
Allikmets, LH; Rägo, LK | 1 |
Cronin, MJ; MacLeod, RM; O'Dell, SB; Schettini, G | 1 |
Cooper, EC; Diamond, I; Gordon, A; Greenberg, DA | 1 |
Scholfield, CN | 1 |
Beani, L; Bianchi, C; Tanganelli, S | 1 |
Kaneto, H; Rahman, AF; Takahashi, M | 1 |
Iwasaki, T; Nakagawa, Y | 1 |
Biggio, G; Concas, A; Cuccheddu, T; Maciocco, E; Santoro, G; Serra, M | 1 |
Fuchs, K; Mossier, B; Sieghart, W; Tögel, M | 1 |
Berman, JA; Pritchett, DB; Roberts, JL | 1 |
Hu, XJ; Ticku, MK | 1 |
Gillard, NP; McKernan, RM; Quirk, K; Ragan, CI; Whiting, PJ | 1 |
Airaksinen, MM; Nieminen, SA; Railoma, O; Titievsky, AV | 1 |
Arbilla, S; Faure-Halley, C; Graham, D; Langer, SZ | 1 |
Emerich, DF; Stackman, RW; Taylor, LA; Walsh, TJ | 1 |
Ishima, T; Iwasaki, T; Kimura, K; Nakagawa, Y | 1 |
Li, S; Pelletier, G | 1 |
Davies, PA; Hales, TG; Hanna, MC; Kirkness, EF | 1 |
Cespuglio, R; Miachon, S | 1 |
Hedblom, E; Kirkness, EF | 1 |
Benke, D; Michel, C; Mohler, H | 1 |
Bergström, M; Långström, B; Matsumura, K; Murata, T; Onoe, H; Sihver, S; Sihver, W; Watanabe, Y; Yonekura, Y | 1 |
Chiu, TH; Li, M; Rosenberg, HC; Walsh, LA; Zhao, TJ | 1 |
Baur, R; Buhr, A; Sigel, E | 1 |
Ansaldo, MA; Fedele, E; Raiteri, M; Varnier, G | 1 |
Ebert, V; Ehya, N; Fuchs, K; Fuchs, T; Klausberger, T; Sarto, I; Sieghart, W | 1 |
Atack, JR; Bromidge, F; Collinson, N; Dawson, GR; Hadingham, KL; Howell, O; Macaulay, A; McKernan, RM; Myers, J; Newman, R; O'Meara, G; Reynolds, DS; Rosahl, TW; Sur, C; Wafford, KA; Whiting, PJ | 1 |
Knight, AR; Ramabahdran, TV; Stephenson, FA; Tallman, JF | 1 |
Copolov, D; Dean, B; Keks, N; McLeod, M; Opeskin, K; Pavey, G | 1 |
Hamann, M; Richter, A | 1 |
Ahboucha, S; Butterworth, RF; Chatauret, N; Desjardins, P; Pomier-Layrargues, G | 1 |
Domínguez, J; García-Alloza, M; Gil-Bea, FJ; Lasheras, B; Marcos, B; Ramírez, MJ | 1 |
Ahboucha, S; Butterworth, RF; Pomier-Layrargues, G | 1 |
Ahboucha, S; Araqi, F; Butterworth, RF; Layrargues, GP | 1 |
Dean, B; McLeod, M; Scarr, E | 1 |
Carta, A; Chopde, CT; Kokare, DM; Patole, AM; Subhedar, NK | 1 |
Jembrek, MJ; Pericić, D; Strac, DS; Vlainić, J | 1 |
Dean, B; McLeod, MC; Sundram, S | 1 |
Czajkowski, C; Sharkey, LM | 1 |
Basile, A | 1 |
Jazvinsćak Jembrek, M; Pericić, D; Svob Strac, D; Vlainić, J | 1 |
Anseloni, VC; Gold, MS | 1 |
Kumar, A; Singh, A | 2 |
Dean, B; McLeod, MC; Scarr, E | 1 |
Kumar, A; Kumar, P; Singh, A | 1 |
Fillman, SG; Verdurand, M; Weickert, CS; Zavitsanou, K | 1 |
Antoni, FA; Barkóczy, J; Belelli, D; Brown, AR; Etherington, LA; Gacsályi, I; Gunn, BG; Kertész, S; Lambert, JJ; Ling, I; Livesey, MR; Mihalik, B; Monteiro, O; Pallagi, K; Pálvölgyi, A; Spedding, M; Varga, P | 1 |
2 review(s) available for muscimol and flumazenil
Article | Year |
---|---|
Memory modulation by brain benzodiazepines.
Topics: Animals; Avoidance Learning; Benzodiazepines; Benzodiazepinones; Brain; Brain Chemistry; Convulsants; Down-Regulation; Flumazenil; Habituation, Psychophysiologic; Memory; Muscimol; Rats | 1991 |
Benzodiazepine receptors resolved.
Topics: Animals; Antibodies, Monoclonal; Autoradiography; Benzodiazepines; Benzodiazepinones; Bicuculline; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Chlorides; Clonazepam; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Histocytochemistry; Humans; Immunologic Techniques; Ionophores; Muscimol; Neurons; Radioisotopes; Radioligand Assay; Receptors, GABA-A; Spinal Cord; Synapses; Tissue Distribution | 1986 |
86 other study(ies) available for muscimol and flumazenil
Article | Year |
---|---|
Regional distribution and kinetics of three sites on the GABAA receptor: lack of effect of portacaval shunting.
Topics: Animals; Autoradiography; Binding Sites; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Flumazenil; Flunitrazepam; Image Processing, Computer-Assisted; Kinetics; Male; Muscimol; Portacaval Shunt, Surgical; Rats; Rats, Inbred Strains; Receptors, GABA-A; Tissue Distribution | 1992 |
[Effects of agonists and antagonists of benzodiazepine, GABA and NMDA receptors, on caffeine-induced seizures in mice].
Topics: Animals; Baclofen; Benzodiazepines; Caffeine; Diazepam; Dizocilpine Maleate; Flumazenil; Male; Mice; Muscimol; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic; Seizures | 1992 |
Intrahippocampal injections of benzodiazepine and muscimol impair working memory but not reference memory of rats in the three-panel runway task.
Topics: Animals; Bicuculline; Chlordiazepoxide; Flumazenil; Hippocampus; Male; Memory; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A | 1992 |
Chronic benzodiazepine administration. VII. Behavioral tolerance and withdrawal and receptor alterations associated with clonazepam administration.
Topics: Animals; Behavior, Animal; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chlorides; Clonazepam; Convulsants; Drug Tolerance; Flumazenil; Male; Mice; Motor Activity; Muscimol; Receptors, GABA-A; Substance Withdrawal Syndrome | 1991 |
Involvement of GABAergic systems in benzodiazepine-induced impairment of passive avoidance learning in mice.
Topics: Animals; Anti-Anxiety Agents; Avoidance Learning; Bicuculline; Chlordiazepoxide; Drug Interactions; Flumazenil; GABA Antagonists; gamma-Aminobutyric Acid; Male; Memory; Mice; Mice, Inbred Strains; Muscimol; Picrotoxin | 1991 |
The effect of medetomidine on GABA and benzodiazepine receptors in vivo: lack of anxiolytic but some evidence of possible stress-protective activity.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Bicuculline; Brain; Cerebral Cortex; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Imidazoles; Kidney; Male; Medetomidine; Muscimol; Myocardium; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures; Stimulation, Chemical; Stress, Physiological; Tritium | 1991 |
The contribution of endogenous benzodiazepine receptor ligands to the pathogenesis of hepatic encephalopathy.
Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chromatography, High Pressure Liquid; Diazepam; Flumazenil; Hepatic Encephalopathy; Kinetics; Ligands; Male; Mass Spectrometry; Muscimol; Peripheral Nerves; Rabbits; Radioligand Assay; Receptors, GABA-A; Sulfur Radioisotopes | 1991 |
Attenuation of benzodiazepine-induced passive avoidance deficit by post-training administration of muscimol: interaction with the cholinergic neuronal system.
Topics: Animals; Anti-Anxiety Agents; Avoidance Learning; Bicuculline; Chlordiazepoxide; Flumazenil; Male; Mice; Mice, Inbred Strains; Muscimol; Neurons; Parasympathetic Nervous System; Receptors, Cholinergic; Receptors, GABA-A; Scopolamine | 1990 |
Similar behavioral and biochemical effects of long-term haloperidol and caerulein treatment in albino mice.
Topics: Amphetamine; Animals; Brain; Ceruletide; Drug Interactions; Exploratory Behavior; Flumazenil; Haloperidol; Male; Mice; Muscimol; Time Factors | 1990 |
Augmentation of GABAA receptor function by chronic exposure to GABA-neutral and GABA-negative benzodiazepine ligands in cultured cortical neurons.
Topics: Animals; Appetite Depressants; Binding Sites; Carbolines; Chick Embryo; Chlorides; Culture Techniques; Flumazenil; Muscimol; Neurons; Ouabain; Receptors, GABA-A | 1990 |
Enkephalin biosynthesis and release in mouse striatum are inhibited by GABA receptor stimulation: compared changes in preproenkephalin mRNA and Tyr-Gly-Gly levels.
Topics: Aminooxyacetic Acid; Animals; Corpus Striatum; Diazepam; Enkephalins; Flumazenil; Kinetics; Leucine; Male; Mice; Muscimol; Oligopeptides; Protein Precursors; Receptors, GABA-A; RNA, Messenger | 1990 |
Post-training down-regulation of memory consolidation by a GABA-A mechanism in the amygdala modulated by endogenous benzodiazepines.
Topics: Amygdala; Animals; Arousal; Avoidance Learning; Benzodiazepines; Dose-Response Relationship, Drug; Down-Regulation; Flumazenil; Male; Mental Recall; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Retention, Psychology | 1990 |
Chronic benzodiazepine administration. II. Discontinuation syndrome is associated with upregulation of gamma-aminobutyric acidA receptor complex binding and function.
Topics: Animals; Binding Sites; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chlorides; Drug Tolerance; Flumazenil; Flunitrazepam; Ion Channels; Lorazepam; Male; Mice; Motor Activity; Muscimol; Receptors, GABA-A; Time Factors | 1988 |
Both systemic and local administration of benzodiazepine agonists inhibit the in vivo release of 5-HT from ventral hippocampus.
Topics: Animals; Benzodiazepines; Carbolines; Chromatography, High Pressure Liquid; Dialysis; Diazepam; Flumazenil; Flurazepam; Hippocampus; Hydroxyindoleacetic Acid; Ion Channels; Male; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Serotonin | 1989 |
Suppression of GABA-induced chloride current by 3-amino-1-methyl-5H-pyrido[4,3-b]indole (Trp-P-2).
Topics: Alanine; Animals; Carbolines; Chlorides; Flumazenil; GABA Antagonists; Ganglia, Spinal; Male; Membrane Potentials; Mice; Mice, Inbred Strains; Muscimol; Neurons, Afferent; Taurine | 1989 |
GABA[A] receptor level changes in female hamster forebrain following in vivo estrogen progesterone and benzodiazepine treatment: a quantitative autoradiography analysis.
Topics: Animals; Autoradiography; Benzodiazepines; Cricetinae; Diazepam; Estradiol; Female; Flumazenil; Frontal Lobe; Muscimol; Ovariectomy; Progesterone; Receptors, GABA-A | 1989 |
Stress-induced behavioral depression in the rat is associated with a decrease in GABA receptor-mediated chloride ion flux and brain benzodiazepine receptor occupancy.
Topics: Animals; Brain; Chlorides; Depression; Flumazenil; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stress, Physiological; Synaptosomes | 1989 |
Chronic clonazepam administration decreases gamma-aminobutyric acidA receptor function in cultured cortical neurons.
Topics: Animals; Benzodiazepines; Cells, Cultured; Cerebral Cortex; Chick Embryo; Chlorides; Clonazepam; Drug Administration Schedule; Flumazenil; Muscimol; Picrotoxin; Receptors, GABA-A; Sesterterpenes | 1989 |
Behavioral analysis of zopiclone on the basis of their discriminative stimulus properties in the rat.
Topics: Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Behavior, Animal; Benzodiazepines; Bicuculline; Discrimination Learning; Dose-Response Relationship, Drug; Flumazenil; Hypnotics and Sedatives; Male; Muscimol; Naphthyridines; Pentylenetetrazole; Piperazines; Piperidines; Rats; Rats, Inbred WKY; Ritanserin; Serotonin Antagonists; Sulfur Compounds | 1989 |
Heterogeneity of gamma-aminobutyric acid/benzodiazepine/beta-carboline receptor complex in rat spinal cord.
Topics: Animals; Bicuculline; Binding, Competitive; Carbolines; Cerebellum; Diazepam; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Receptors, GABA-A; Spinal Cord; Synaptic Membranes | 1988 |
Benzodiazepines and barbiturate potentiate the pre- and postsynaptic gamma-aminobutyric acid (GABA)A receptor-mediated response in the enteric nervous system of guinea pig small intestine.
Topics: Acetylcholine; Animals; Barbiturates; Benzodiazepines; Clonazepam; Diazepam; Female; Flumazenil; Guinea Pigs; Intestine, Small; Male; Muscimol; Pentobarbital; Potassium; Receptors, GABA-A | 1988 |
Involvement of GABAergic systems and benzodiazepine receptors in the jumping behavior induced by harmine and apomorphine in rats.
Topics: Alkaloids; Animals; Apomorphine; Brain; Diazepam; Flumazenil; Harmine; Hydroxydopamines; Male; Motor Activity; Muscimol; Oxidopamine; Pyridines; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1988 |
Modulation of the GABA autoreceptor by benzodiazepine receptor ligands.
Topics: Animals; Bicuculline; Carbolines; Clonazepam; Flumazenil; Ligands; Male; Muscimol; Rats; Receptors, GABA-A | 1988 |
Drugs which stimulate or facilitate central GABAergic transmission interact synergistically with delta-9-tetrahydrocannabinol to produce marked catalepsy in mice.
Topics: Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Catalepsy; Dronabinol; Drug Synergism; Flumazenil; Flupenthixol; Flurazepam; GABA Antagonists; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Nipecotic Acids; Receptors, GABA-A; Strychnine; Taurine; Tiagabine | 1988 |
Differential responsiveness of cerebellar Purkinje neurons to GABA and benzodiazepine receptor ligands in an animal model of hepatic encephalopathy.
Topics: Animals; Benzodiazepines; Flumazenil; Flunitrazepam; GABA Antagonists; Galactosamine; Hepatic Encephalopathy; Ligands; Male; Muscimol; Purkinje Cells; Rabbits; Receptors, GABA-A | 1988 |
Functional coupling of gamma-aminobutyric acid (GABA)A and benzodiazepine type II receptors: analysis using purified GABA/benzodiazepine receptor complex from bovine cerebral cortex.
Topics: Animals; Antipsychotic Agents; Bicuculline; Cattle; Cerebral Cortex; Flumazenil; Flunitrazepam; In Vitro Techniques; Kinetics; Muscimol; Pyridazines; Receptors, GABA-A | 1987 |
Discriminative-stimulus effects of midazolam in squirrel monkeys: comparison with other drugs and antagonism by Ro 15-1788.
Topics: Animals; Azabicyclo Compounds; Barbital; Benzodiazepines; Benzodiazepinones; Buspirone; Caffeine; Chlordiazepoxide; Cinanserin; Clozapine; Conditioning, Operant; Cyproheptadine; Diazepam; Diphenhydramine; Discrimination Learning; Electroshock; Flumazenil; Male; Midazolam; Muscimol; Nordazepam; Pentobarbital; Piperazines; Pyridazines; Pyrimidines; Saimiri; Tripelennamine | 1985 |
D1- and D2-receptor antagonists induce catalepsy via different efferent striatal pathways [corrected].
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Catalepsy; Corpus Striatum; Dose-Response Relationship, Drug; Flumazenil; Injections, Intraperitoneal; Male; Muscimol; Raclopride; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Salicylamides; Scopolamine | 1988 |
Modulation of acetylcholine release from rat striatal slices by the GABA/benzodiazepine receptor complex.
Topics: Acetylcholine; Animals; Atropine; Baclofen; Benzodiazepinones; Clonazepam; Corpus Striatum; Electric Stimulation; Flumazenil; gamma-Aminobutyric Acid; Haloperidol; In Vitro Techniques; Isoxazoles; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1985 |
Radiation inactivation studies of the benzodiazepine/gamma-aminobutyric acid/chloride ionophore receptor complex.
Topics: Animals; Barbiturates; Benzodiazepines; Benzodiazepinones; Binding Sites; Brain; Carbolines; Cell Membrane; Chlorides; Diazepam; Flumazenil; Flunitrazepam; Ionophores; Male; Molecular Weight; Muscimol; Picrotoxin; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1985 |
Antagonism of flurazepam and other effects of Ro15-1788, PK8165 and Ro5-4864 on the GABA-A receptor complex in rat cuneate nucleus.
Topics: Animals; Anticonvulsants; Benzodiazepinones; Drug Synergism; Flumazenil; Flurazepam; In Vitro Techniques; Male; Medulla Oblongata; Muscimol; Pentobarbital; Picrotoxin; Quinolines; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1985 |
Regional difference in brain benzodiazepine receptor carbohydrates.
Topics: Acetylglucosaminidase; Animals; Asparagine; Benzodiazepinones; Brain Chemistry; Carbohydrates; Electrophoresis, Polyacrylamide Gel; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Male; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Molecular Weight; Muscimol; Neuraminidase; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sialic Acids; Tritium | 1986 |
[Nonuniform effect of prolonged haloperidol administration on the GABA(A) and benzodiazepine receptors in different parts of the brain].
Topics: Animals; Behavior, Animal; Benzodiazepinones; Brain; Flumazenil; Haloperidol; Male; Mice; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Time Factors | 1986 |
Interactions of Ro 15-1788, CGS 8216 and diazepam on head-turning in rats.
Topics: Animals; Benzodiazepinones; Diazepam; Drug Interactions; Electric Stimulation; Flumazenil; Head; Male; Movement; Muscimol; Pyrazoles; Rats; Rats, Inbred Strains | 1986 |
Diazepam-induced decrease in histamine turnover in mouse brain.
Topics: Animals; Benzodiazepinones; Brain; Diazepam; Drug Interactions; Flumazenil; Histamine; Male; Methylhistamines; Mice; Muscimol; Pargyline | 1986 |
CL 218,872 binding to benzodiazepine receptors in rat spinal cord: modulation by gamma-aminobutyric acid and evidence for receptor heterogeneity.
Topics: Animals; Benzodiazepinones; Cerebral Cortex; Flumazenil; gamma-Aminobutyric Acid; Male; Muscimol; Pyridazines; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Spinal Cord | 1984 |
Differential modulation of etazolate or pentobarbital enhanced [3H] muscimol binding by benzodiazepine agonists and inverse agonists.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Binding, Competitive; Carbolines; Cell Membrane; Cerebral Cortex; Convulsants; Etazolate; Flumazenil; Flunitrazepam; Kinetics; Muscimol; Nicotinic Acids; Oxazoles; Pentobarbital; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Increase of cyclic GMP in cerebellum by methyl-6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate (DMCM).
Topics: Animals; Benzodiazepinones; Carbolines; Cerebellar Cortex; Cyclic GMP; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Indoles; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Stimulation, Chemical | 1983 |
The action of benzodiazepine antagonist Ro 15-1788 on the effects of GABA-ergic drugs.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aggression; Animals; Baclofen; Benzodiazepines; Benzodiazepinones; Brain Chemistry; Flumazenil; gamma-Aminobutyric Acid; Humans; Male; Motor Activity; Muscimol; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
The benzodiazepine agonist diazepam inhibits basal and secretagogue-stimulated prolactin release in vitro.
Topics: Animals; Benzodiazepinones; Calcimycin; Cells, Cultured; Cyclic AMP; Diazepam; Drug Interactions; Female; Flumazenil; In Vitro Techniques; Male; Muscimol; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains; Thyrotropin | 1984 |
Ethanol and the gamma-aminobutyric acid-benzodiazepine receptor complex.
Topics: Animals; Benzodiazepinones; Brain; Carbolines; Ethanol; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Male; Membranes; Muscimol; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Temperature | 1984 |
Ro 15-1788 is a potent antagonist of benzodiazepines in the olfactory cortex slice.
Topics: Anesthetics; Animals; Benzodiazepines; Benzodiazepinones; Cerebral Cortex; Dose-Response Relationship, Drug; Flumazenil; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Muscimol | 1983 |
Diazepam antagonizes GABA- and muscimol-induced changes of acetylcholine release in slices of guinea-pig cerebral cortex.
Topics: Acetylcholine; Animals; Benzodiazepinones; Cerebral Cortex; Diazepam; Flumazenil; GABA Antagonists; Guinea Pigs; In Vitro Techniques; Muscimol; Oxazoles | 1983 |
Role of GABAergic systems in the development of morphine tolerance in formalin-treated mice.
Topics: Analgesics, Opioid; Animals; Baclofen; Bicuculline; Diazepam; Drug Tolerance; Flumazenil; Formaldehyde; GABA Agonists; GABA Antagonists; Male; Mice; Mice, Inbred Strains; Morphine; Muscimol; Pain; Pain Measurement; Receptors, GABA | 1995 |
Involvement of benzodiazepine/GABA-A receptor complex in ethanol-induced state-dependent learning in rats.
Topics: Animals; Avoidance Learning; Azides; Benzodiazepines; Bicuculline; Diazepam; Ethanol; Evaluation Studies as Topic; Flumazenil; Male; Muscimol; Picrotoxin; Rats; Rats, Wistar; Reaction Time; Receptors, GABA-A | 1995 |
The effect of cyclopyrrolones on GABAA receptor function is different from that of benzodiazepines.
Topics: Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Benzodiazepines; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chlorides; Chlorine; Flumazenil; Hypnotics and Sedatives; Kinetics; Male; Mice; Mice, Inbred Strains; Muscimol; Naphthyridines; Piperazines; Radioisotopes; Receptors, GABA-A; Sulfur Compounds; Sulfur Radioisotopes; Tritium | 1994 |
Immunoaffinity purification of gamma-aminobutyric acidA (GABAA) receptors containing gamma 1-subunits. Evidence for the presence of a single type of gamma-subunit in GABAA receptors.
Topics: Animals; Antibody Specificity; Base Sequence; Blotting, Western; Brain Chemistry; Chromatography, Affinity; Clonazepam; Enzyme-Linked Immunosorbent Assay; Flumazenil; Flunitrazepam; Immunologic Techniques; Molecular Sequence Data; Molecular Weight; Muscimol; Peptide Fragments; Protein Conformation; Rats; Receptors, GABA-A; Recombinant Fusion Proteins | 1994 |
Molecular and pharmacological characterization of GABAA receptors in the rat pituitary.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; DNA; Flumazenil; Male; Muscimol; Pituitary Gland; Polymerase Chain Reaction; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; RNA, Messenger; Tritium | 1994 |
Development pattern of the GABAA-benzodiazepine receptor ionophore complex in primary cultures of cortical neurons.
Topics: Affinity Labels; Animals; Azides; Benzodiazepines; Cells, Cultured; Cerebral Cortex; Chlorides; Flumazenil; Flunitrazepam; Mice; Mice, Inbred C57BL; Muscimol; Neurons; Receptors, GABA-A | 1994 |
Model of subunit composition of gamma-aminobutyric acid A receptor subtypes expressed in rat cerebellum with respect to their alpha and gamma/delta subunits.
Topics: Animals; Azides; Base Sequence; Benzodiazepines; Cerebellum; Escherichia coli; Flumazenil; Molecular Sequence Data; Muscimol; Precipitin Tests; Protein Conformation; Rats; Receptors, GABA-A; Recombinant Proteins | 1994 |
Influence of flumazenil on the learning-enhancing effect of ambocarb in rats.
Topics: Animals; Behavior, Animal; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Discrimination Learning; Discrimination, Psychological; Flumazenil; Flunitrazepam; Harmine; Learning; Ligands; Male; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A | 1994 |
Expression and properties of recombinant alpha 1 beta 2 gamma 2 and alpha 5 beta 2 gamma 2 forms of the rat GABAA receptor.
Topics: Animals; Binding, Competitive; Flumazenil; Humans; Muscimol; Radioligand Assay; Rats; Receptors, GABA-A; Recombinant Proteins | 1993 |
Intraseptal injection of GABA and benzodiazepine receptor ligands alters high-affinity choline transport in the hippocampus.
Topics: Acetylcholinesterase; Animals; Baclofen; Brain; Carbolines; Chlordiazepoxide; Choline; Convulsants; Flumazenil; gamma-Aminobutyric Acid; Hippocampus; Injections; Male; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synaptosomes | 1993 |
Interaction between benzodiazepine and GABA-A receptors in state-dependent learning.
Topics: Animals; Avoidance Learning; Baclofen; Bicuculline; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Male; Muscimol; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Reference Values | 1993 |
Further studies on the mechanism of action of the endogenous benzodiazepine receptor ligand octadecaneuropeptide on gonadotropin-releasing hormone gene expression in the rat brain.
Topics: Animals; Diazepam Binding Inhibitor; Drug Synergism; Flumazenil; GABA Antagonists; GABA Modulators; Gene Expression; Gonadotropin-Releasing Hormone; Male; Muscimol; Neuropeptides; Peptide Fragments; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; RNA, Messenger | 1996 |
Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit.
Topics: Amino Acid Sequence; Anesthetics, Intravenous; Animals; Bicuculline; Brain; Cell Line; Consensus Sequence; DNA, Complementary; Flumazenil; Flunitrazepam; GABA Agents; gamma-Aminobutyric Acid; Humans; Molecular Sequence Data; Muscimol; Pentobarbital; Picrotoxin; Pregnanolone; Propofol; Rats; Receptors, GABA-A; Recombinant Proteins; RNA, Messenger; Transfection | 1997 |
Prevention of ACTH- and adrenalectomy-induced muricidal behavior: by benzodiazepinic ligands.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Aggression; Animals; Benzodiazepinones; Clonazepam; Flumazenil; GABA Modulators; Isoquinolines; Male; Mice; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A; Time Factors | 1997 |
A novel class of GABAA receptor subunit in tissues of the reproductive system.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Cloning, Molecular; DNA, Complementary; Flumazenil; Humans; Molecular Sequence Data; Muscimol; Radioligand Assay; Rats; Receptors, GABA-A; RNA, Messenger | 1997 |
GABA(A) receptors containing the alpha4-subunit: prevalence, distribution, pharmacology, and subunit architecture in situ.
Topics: Animals; Azides; Benzodiazepines; Benzodiazepinones; Brain; Cell Membrane; Cerebellum; Diazepam; Flumazenil; Immunohistochemistry; Immunosorbent Techniques; Macromolecular Substances; Male; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Recombinant Proteins | 1997 |
Triazolam-induced modulation of muscarinic acetylcholine receptor in living brain slices as revealed by a new positron-based imaging technique.
Topics: Animals; Brain; Flumazenil; GABA Agonists; In Vitro Techniques; Male; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Tomography, Emission-Computed; Triazolam | 1998 |
Acute pentylenetetrazol injection reduces rat GABAA receptor mRNA levels and GABA stimulation of benzodiazepine binding with No effect on benzodiazepine binding site density.
Topics: Animals; Autoradiography; Brain; Down-Regulation; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Male; Muscimol; Pentylenetetrazole; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; RNA, Messenger; Time Factors; Transcription, Genetic; Tritium | 1999 |
Role of the conserved lysine residue in the middle of the predicted extracellular loop between M2 and M3 in the GABA(A) receptor.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Bicuculline; Binding, Competitive; Cell Line; Conserved Sequence; Female; Flumazenil; gamma-Aminobutyric Acid; Humans; Kinetics; Lysine; Muscimol; Mutagenesis, Site-Directed; Oocytes; Protein Structure, Secondary; Radioligand Assay; Rats; Receptors, GABA-A; Recombinant Proteins; Sequence Alignment; Transfection; Xenopus laevis | 1999 |
Benzodiazepine-sensitive GABA(A) receptors limit the activity of the NMDA/NO/cyclic GMP pathway: a microdialysis study in the cerebellum of freely moving rats.
Topics: Animals; Anti-Anxiety Agents; Bicuculline; Cerebellum; Cyclic GMP; Diazepam; Flumazenil; Infusions, Parenteral; Kinetics; Male; Microdialysis; Muscimol; N-Methylaspartate; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Zolpidem | 2000 |
Detection and binding properties of GABA(A) receptor assembly intermediates.
Topics: Animals; Brain; Cell Line; Dimerization; Flumazenil; Humans; Immunohistochemistry; Kidney; Macromolecular Substances; Muscimol; Polymerase Chain Reaction; Protein Subunits; Radioligand Assay; Rats; Receptors, GABA-A; Recombinant Proteins; Transfection; Tritium | 2001 |
Loss of the major GABA(A) receptor subtype in the brain is not lethal in mice.
Topics: Animals; Autoradiography; Behavior, Animal; Binding, Competitive; Brain; Bridged Bicyclo Compounds, Heterocyclic; Cerebellum; Electrophysiology; Flumazenil; Gait Disorders, Neurologic; Gene Expression; Homozygote; Ligands; Mice; Mice, Inbred Strains; Mice, Knockout; Motor Activity; Muscimol; Protein Subunits; Purkinje Cells; Radioligand Assay; Receptors, GABA-A; Survival Rate; Tissue Distribution | 2001 |
Monospecific antibodies as probes for the stoichiometry of recombinant GABA(A) receptors.
Topics: Antibodies, Monoclonal; Antibody Specificity; Antigen-Antibody Complex; Epitopes; Flumazenil; GABA Agonists; Humans; Molecular Probes; Muscimol; Protein Conformation; Protein Subunits; Receptors, GABA-A; Recombinant Proteins | 2000 |
A change in the density of [(3)H]flumazenil, but not [(3)H]muscimol binding, in Brodmann's Area 9 from subjects with bipolar disorder.
Topics: Adult; Aged; Autoradiography; Bipolar Disorder; Brain Mapping; Female; Flumazenil; Frontal Lobe; Humans; Male; Middle Aged; Muscimol; Radioligand Assay; Receptors, GABA-A; Schizophrenia | 2001 |
Effects of striatal injections of GABA(A) receptor agonists and antagonists in a genetic animal model of paroxysmal dystonia.
Topics: Animals; Bicuculline; Binding Sites; Corpus Striatum; Cricetinae; Dystonia; Female; Flumazenil; Flurazepam; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Male; Mesocricetus; Microinjections; Muscimol; Pentylenetetrazole; Phenobarbital | 2002 |
Normal coupling of brain benzodiazepine and neurosteroid modulatory sites on the GABA-A receptor complex in human hepatic encephalopathy.
Topics: Adult; Aged; Aged, 80 and over; Brain; Female; Flumazenil; Flunitrazepam; Hepatic Encephalopathy; Humans; Intracranial Aneurysm; Kinetics; Male; Middle Aged; Muscimol; Receptors, GABA-A; Reference Values; Shock, Septic | 2003 |
Facilitation of cholinergic transmission by combined treatment of ondansetron with flumazenil after cortical cholinergic deafferentation.
Topics: Acetylcholine; Afferent Pathways; Animals; Cerebral Cortex; Denervation; Flumazenil; GABA Agonists; GABA Modulators; GABA-A Receptor Antagonists; Granisetron; Male; Muscimol; Ondansetron; Parasympathetic Nervous System; Potassium; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Synaptic Transmission | 2004 |
Increased brain concentrations of endogenous (non-benzodiazepine) GABA-A receptor ligands in human hepatic encephalopathy.
Topics: Adult; Aged; Aged, 80 and over; Allosteric Regulation; Animals; Benzodiazepines; Binding Sites; Binding, Competitive; Brain; Female; Flumazenil; GABA Agonists; GABA Modulators; Hepatic Encephalopathy; Humans; Ligands; Male; Middle Aged; Muscimol; Radioligand Assay; Rats; Receptors, GABA-A; Steroids; Tritium; Up-Regulation | 2004 |
Differential effects of ammonia on the benzodiazepine modulatory site on the GABA-A receptor complex of human brain.
Topics: Ammonia; Binding Sites; Binding, Competitive; Brain; Cell Membrane; Dose-Response Relationship, Drug; Down-Regulation; Flumazenil; Flunitrazepam; GABA Agonists; GABA Modulators; Hepatic Encephalopathy; Humans; Hyperammonemia; Ligands; Muscimol; Radioligand Assay; Receptors, GABA-A; Subcellular Fractions; Synaptic Transmission; Tartrates | 2005 |
Changes in hippocampal GABAA receptor subunit composition in bipolar 1 disorder.
Topics: Adult; Aged; Binding, Competitive; Bipolar Disorder; Brain Chemistry; Clonazepam; Female; Flumazenil; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Hippocampus; Humans; Male; Middle Aged; Muscimol; Protein Subunits; Pyridines; Radioligand Assay; Receptors, GABA-A; Schizophrenia; Zolpidem | 2005 |
GABA(A) receptors mediate orexin-A induced stimulation of food intake.
Topics: Animals; Diazepam; Dose-Response Relationship, Drug; Eating; Flumazenil; GABA Agonists; GABA Antagonists; GABA Modulators; GABA-A Receptor Antagonists; Hyperphagia; Injections, Intraventricular; Intracellular Signaling Peptides and Proteins; Male; Muscimol; Neuropeptides; Orexin Receptors; Orexins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, GABA-A; Receptors, Neuropeptide; Stimulation, Chemical | 2006 |
Allosteric uncoupling and up-regulation of benzodiazepine and GABA recognition sites following chronic diazepam treatment of HEK 293 cells stably transfected with alpha1beta2gamma2S subunits of GABA (A) receptors.
Topics: Allosteric Regulation; Animals; Benzodiazepines; Binding Sites; Binding, Competitive; Cell Line; Diazepam; Flumazenil; Flunitrazepam; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Muscimol; Picrotoxin; Protein Subunits; Pyridazines; Radioligand Assay; Rats; Receptors, GABA-A; Receptors, GABA-B; Transfection; Up-Regulation | 2007 |
Treatment with haloperidol and diazepam alters GABA(A) receptor density in the rat brain.
Topics: Animals; Antipsychotic Agents; Autoradiography; Benzodiazepines; Binding Sites; Brain; Diazepam; Disease Models, Animal; Drug Combinations; Flumazenil; Haloperidol; Hippocampus; Humans; Injections, Intraperitoneal; Muscimol; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Schizophrenia; Thalamus; Tissue Distribution | 2008 |
Individually monitoring ligand-induced changes in the structure of the GABAA receptor at benzodiazepine binding site and non-binding-site interfaces.
Topics: Animals; Benzodiazepines; Binding Sites; Cysteine; Dose-Response Relationship, Drug; Electrophysiology; Female; Flumazenil; Flurazepam; GABA Agonists; GABA Antagonists; GABA Modulators; Inhibitory Concentration 50; Ligands; Microinjections; Muscimol; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Pentobarbital; Pyridazines; Rats; Receptors, GABA-A; Xenopus | 2008 |
Saturation assays of radioligand binding to receptors and their allosteric modulatory sites.
Topics: Allosteric Site; Animals; Binding Sites; Binding, Competitive; Flumazenil; gamma-Aminobutyric Acid; Ligands; Muscimol; Nerve Tissue Proteins; Protein Binding; Radioligand Assay; Rats; Receptors, GABA-A; Tritium | 2001 |
The role of transcriptional and translational mechanisms in flumazenil-induced up-regulation of recombinant GABA(A) receptors.
Topics: Analysis of Variance; Cell Line, Transformed; Cell Proliferation; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Drug Interactions; Flumazenil; Flunitrazepam; GABA Modulators; Humans; Muscimol; Protein Biosynthesis; Protein Synthesis Inhibitors; Receptors, GABA-A; RNA, Messenger; Transcription, Genetic; Transcriptional Activation; Transfection; Tritium; Up-Regulation | 2008 |
Inflammation-induced shift in the valence of spinal GABA-A receptor-mediated modulation of nociception in the adult rat.
Topics: Animals; Antineoplastic Agents; Flumazenil; Freund's Adjuvant; GABA Agonists; GABA Antagonists; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Hyperalgesia; Inflammation; Injections, Spinal; Isoquinolines; Male; Midazolam; Muscimol; Nociceptors; Pain Measurement; Pain Threshold; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Signal Transduction; Spinal Cord | 2008 |
Possible GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice.
Topics: Animals; Anxiety; Behavior, Animal; Body Weight; Catalase; Dose-Response Relationship, Drug; Flumazenil; GABA Agonists; GABA Antagonists; GABA Modulators; Glutathione; Lipid Peroxidation; Male; Maze Learning; Mice; Motor Activity; Muscimol; Neuroprotective Agents; Nitrites; Oxidative Stress; Picrotoxin; Pregnanolone; Sleep Deprivation | 2008 |
Possible involvement of GABAergic mechanism in protective effect of melatonin against sleep deprivation-induced behaviour modification and oxidative damage in mice.
Topics: Animals; Antioxidants; Anxiety; Behavior, Animal; Body Weight; Dose-Response Relationship, Drug; Female; Flumazenil; GABA Agonists; GABA Antagonists; GABA Modulators; Lipid Peroxidation; Male; Maze Learning; Melatonin; Mice; Motor Activity; Muscimol; Oxidative Stress; Picrotoxin; Sleep Deprivation | 2009 |
Effects of benzodiazepine treatment on cortical GABA(A) and muscarinic receptors: studies in schizophrenia and rats.
Topics: Adult; Aged; Analysis of Variance; Animals; Benzodiazepines; Cerebral Cortex; Female; Flumazenil; GABA Agents; Humans; Male; Middle Aged; Muscarinic Antagonists; Muscimol; Pirenzepine; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Muscarinic; Schizophrenia; Tritium; Young Adult | 2010 |
Possible involvement of GABAergic mechanism in protective effect of melatonin against sleep deprivation-induced behavior modification and oxidative damage in mice.
Topics: Animals; Antioxidants; Anxiety; Behavior, Animal; Flumazenil; GABA Modulators; gamma-Aminobutyric Acid; Lipid Peroxidation; Male; Melatonin; Mice; Motor Activity; Muscimol; Oxidative Stress; Picrotoxin; Sleep Deprivation | 2011 |
Increases in [3H]muscimol and [3H]flumazenil binding in the dorsolateral prefrontal cortex in schizophrenia are linked to α4 and γ2S mRNA levels respectively.
Topics: Adult; Aged; Allosteric Site; Autoradiography; Case-Control Studies; Cohort Studies; Female; Flumazenil; GABA Modulators; GABA-A Receptor Agonists; Humans; Male; Middle Aged; Muscimol; Prefrontal Cortex; Protein Subunits; Receptors, GABA-A; RNA, Messenger; Schizophrenia | 2013 |
Selective inhibition of extra-synaptic α5-GABA
Topics: Animals; Benzodiazepines; Binding, Competitive; Brain; Female; Flumazenil; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; HEK293 Cells; Humans; Long-Term Potentiation; Male; Memory; Mice, Inbred C57BL; Muscimol; Neural Inhibition; Nootropic Agents; Oxazoles; Rats, Sprague-Dawley; Receptors, GABA-A; Tissue Culture Techniques | 2017 |