muscimol has been researched along with diazepam in 236 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 135 (57.20) | 18.7374 |
| 1990's | 71 (30.08) | 18.2507 |
| 2000's | 20 (8.47) | 29.6817 |
| 2010's | 9 (3.81) | 24.3611 |
| 2020's | 1 (0.42) | 2.80 |
| Authors | Studies |
|---|---|
| Howard, HR; Koe, BK; Sarges, R; Weissman, A | 1 |
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Bartoccini, F; Carminati, P; Castorina, M; Di Cesare, MA; Di Serio, S; Gallo, G; Ghirardi, O; Giorgi, F; Giorgi, L; Minetti, P; Piersanti, G; Tarzia, G; Tinti, MO | 1 |
| Gallager, DW; Tallman, JF | 1 |
| Jobert, A; Soubrié, P; Thiébot, MH | 2 |
| Bertilsson, L | 1 |
| Longman, DA; Slater, P | 1 |
| Karobath, M; Sperk, G | 1 |
| Gallager, DW; Tallman, JF; Thomas, JW | 1 |
| Risley, EA; Williams, M | 1 |
| Braestrup, C; Falch, E; Krogsgaard-Larsen, P; Nielsen, M | 2 |
| Maurer, R | 1 |
| Marusov, IV; Val'dman, AV | 1 |
| Chéramy, A; Glowinski, J; Leviel, V; Nieoullon, A | 1 |
| Antonaccio, MJ; Kerwin, L; Taylor, DG | 1 |
| Briley, MS; Langer, SZ | 1 |
| Brown, GB; DeLorey, TM | 1 |
| Amabeoku, GJ; Chikuni, O | 2 |
| Bertrand, PP; Galligan, JJ | 1 |
| Hales, TG; Kim, H; Longoni, B; Olsen, RW; Tobin, AJ | 1 |
| Skolnick, P; Wong, G | 1 |
| Golovko, AI; Sofronov, GA | 1 |
| Inano, S | 1 |
| Rochford, J; Stewart, J | 1 |
| Kokka, N; Olsen, RW; Sapp, DW; Witte, U | 1 |
| Bertherat, J; Epelbaum, J; Jomary, C; Kordon, C; Llorens-cortes, C | 1 |
| Allan, AM; Baier, LD | 1 |
| Aibara, K; Akaike, N; Itabashi, S; Sasaki, H | 1 |
| Amabeoku, G | 1 |
| Allan, AM; Draski, LJ; Mayes, GG | 1 |
| Kariya, T; Motohashi, N; Shioe, K | 1 |
| Gautam, SK; Kulkarni, SK | 1 |
| Maisky, A; Rebrov, I; Tennila, T; Yukhananov, R | 1 |
| Corbett, R; Cornfeldt, M; Dunn, RW; Fielding, S | 1 |
| Oien, TT; Sethy, VH | 1 |
| Niles, L | 1 |
| Conci, F; Ferrario, P; Hafner, B; Mantegazza, P; Tammiso, R; Zambotti, F; Zecca, L; Zonta, N | 1 |
| Brett, RR; Pratt, JA | 1 |
| Basile, AS | 1 |
| Kang, T; Xiao-Hong, D; Xin-Quan, J | 1 |
| Albers, HE; Liou, SY; Shibata, S; Ueki, S | 1 |
| Giros, B; Llorens-Cortes, C; Quach, TT; Schwartz, JC | 1 |
| Huang, JH; Johnston, GA | 1 |
| Dodd, PR; Gundlach, AL; Harper, PA; Johnston, GA; Lummis, SC | 1 |
| Kim, KH; Takeuchi, H | 1 |
| Pericić, D; Tvrdeić, A | 1 |
| Giros, B; Llorens-Cortes, C; Quach, TT; Schwartz, JC; Van Amsterdam, JG | 1 |
| Jones, TA; Lindner, MD; Schallert, T | 1 |
| Cañadas, S; Giménez, A; González, MP; Sánchez, C | 1 |
| Akagi, H; Yanagisawa, M | 1 |
| Allan, AM; Gallaher, EJ; Gionet, SE; Harris, RA | 1 |
| Schneider, HH; Stephens, DN; Weidmann, R; Zimmermann, L | 1 |
| Akaike, N; Ikemoto, Y; Kijima, H | 1 |
| Barry, D; Clemmesen, L; Hemmingsen, R; Ulrichsen, J | 1 |
| Fukuda, H; Matsumoto, K; Ono, H; Yamazaki, J | 1 |
| Maggi, A; Perez, J; Zucchi, I | 1 |
| Fillenz, M; Pei, Q; Zetterström, T | 1 |
| Bleck, V; Harris, RA; Lewin, E; Peris, J; Zahniser, NR | 1 |
| Besson, MJ; Caboche, J; Le Saux, F; Maurin, Y; Mitrovic, N; Sauter, A | 1 |
| Biggio, G; Concas, A; Corda, MG; Serra, M | 1 |
| Enjalbert, A; Kordon, C; Lechat, P; Lloyd, KG; Paillard, JJ; Thuret, F; Vincens, M | 1 |
| Canonaco, M; McEwen, BS; O'Connor, LH; Pfaff, DW | 1 |
| Kardos, J | 1 |
| Cox, DH; Guidotti, A; Santi, MR | 1 |
| Coloma, FM; Niles, LP | 1 |
| Hanada, S; Hashimoto, S; Tanaka, C; Taniyama, K | 1 |
| Maksay, G | 1 |
| Bigl, V; Middleton-Price, H; Rothe, T | 1 |
| Kuga, T; Moroi, K; Takashi, K | 1 |
| Mori, A; Shigara, H; Shiraga, H; Tsuruta, K; Yokoi, I | 1 |
| Harro, J; Kiivet, RA; Pŏld, M; Rägo, L | 1 |
| Crocker, AD; Overstreet, DH; Pepe, S | 1 |
| Cavalla, D; Neff, NH | 1 |
| Chuang, DM; Majewska, MD | 1 |
| Meldrum, BS | 1 |
| Handley, SL; Heaton, JC; Rea, PJ; Singh, L | 1 |
| Goddard, GV; Holmes, KH; Morimoto, K | 1 |
| Kataoka, Y; Shibata, K; Ueki, S; Yamashita, K | 1 |
| Atsoggiu, T; Biggio, G; Concas, A; Serra, M | 1 |
| Spealman, RD | 1 |
| Iversen, LL; Wong, EH | 1 |
| Kempner, ES; Paul, SM; Schwartz, RD; Skolnick, P; Thomas, JW | 1 |
| Fukuda, H; Kato, K | 1 |
| Lee, RJ; Lomax, P; McCabe, RT; Olsen, RW; Wamsley, JK | 1 |
| Curtis, DR; Falch, E; Krogsgaard-Larsen, P; Nielsen, L | 1 |
| Creveling, CR; Daly, JW; Hollingsworth, EB; Lewandowski, G; Waters, JA | 1 |
| Maksay, G; Nielsen, M; Simonyi, M | 1 |
| Chow, SC; Holan, G; Johnston, GA; Lummis, SC | 1 |
| Crofton, KM; Mailman, RB; Reiter, LW | 1 |
| Costa, LG; Murphy, SD | 1 |
| Goldstein, JM; Malick, JB; Sutton, EB | 1 |
| Itoh, Y; Nishibori, M; Oishi, R; Saeki, K | 1 |
| Calogero, AE; Chrousos, GP; Gallucci, WT; Gold, PW | 1 |
| Akaike, N; Behrends, JC; Maruyama, T | 1 |
| Perry, DC | 1 |
| Morrow, AL; Paul, SM | 1 |
| Alvinerie, M; Bueno, L; Fioramonti, J; Frexinos, J; Gue, M | 1 |
| Benistant, C; Fonlupt, P; Pacheco, H; Rey, C | 1 |
| Bagetta, G; Corasaniti, MT; Froio, F; Nisticò, G; Sakurada, S | 1 |
| Kawabata, Y; Kontani, H; Koshiura, R | 1 |
| Cupello, A; Hyden, H; Palm, A | 1 |
| Ford, I; Kelly, PA; McCulloch, J | 1 |
| Bueno, L; Gué, M | 1 |
| Borenstein, P; Pointis, D | 1 |
| Gallo, V; Guidotti, A; Vaccarino, F; Wise, BC | 1 |
| Braestrup, C; Tacke, U | 1 |
| Hamon, M; Hery, F; Jobert, A; Montastruc, JL; Soubrie, P; Thiebot, MH | 1 |
| Christensen, AV; Scheel-Krüger, J | 1 |
| Sillén, U | 1 |
| Saano, V | 1 |
| Ostrovskaia, RU | 1 |
| Blanchard, JC; Boireau, A; Garret, C; Julou, L; Stutzmann, JM | 1 |
| Risley, EA; Totaro, JA; Williams, M | 1 |
| Biggio, G; Corda, MG; Gessa, GL | 1 |
| Axelrod, J; Gallager, DW; Hirata, F; Mallorga, P; Strittmatter, W; Tallman, JF; Thomas, JW | 1 |
| Cananzi, AR; Costa, E; Guidotti, A | 1 |
| Alleva, FR; Balazs, T; Guidotti, A; Massotti, M | 1 |
| Persson, B; Rubenson, A; Sillén, U | 1 |
| Irmscher, K; Jones, R; Lock, KL; Marangos, PJ; Paul, SM; Skolnick, P | 1 |
| Martin, I; Mitchell, R | 1 |
| Biggio, G; Concas, A; Corda, MG; Guarneri, P | 1 |
| Gardell, MA; Neale, JH; Shibla, DB | 1 |
| Davis, WC; Ticku, MK | 1 |
| Costa, E; Guidotti, A; Massotti, M | 1 |
| Burch, TP; Ticku, MK | 1 |
| Por, SB | 1 |
| Marangos, PJ; Martino, AM | 1 |
| Biggio, G; Concas, A; Corda, MG; Corongiu, FP; Guarneri, P; Rossetti, Z | 1 |
| Braestrup, C; Nielsen, M | 1 |
| Cavagnini, F; Grandison, L; Guidotti, A; Invitti, SC; Schmid, R | 1 |
| Ito, Y; Kuriyama, K | 1 |
| Wood, PL | 1 |
| Gardner, CR; Piper, DC | 1 |
| Etienne, P; Lal, S; Nair, NP; Wood, PL | 1 |
| Fujimoto, M; Okabayashi, T | 1 |
| Del Zompo, M; Post, RM; Tallman, JF | 1 |
| Burch, TP; Thyagarajan, R; Ticku, MK | 1 |
| Riley, M; Scholfield, CN | 1 |
| Biggio, G; Concas, A; Salis, M; Serra, M | 1 |
| Alberici, GF; Bidart, JM; Bohuon, C; Moingeon, P | 1 |
| Fukuda, H; Goto, M; Saito, K | 1 |
| Johnston, GA; Skerritt, JH | 1 |
| Adamec, R; Racine, RJ; Tuff, LP | 1 |
| Cronin, MJ; MacLeod, RM; O'Dell, SB; Schettini, G | 1 |
| Kato, R; Muraki, T; Yamazoe, Y | 1 |
| Costa, E; Ferrero, P; Guidotti, A | 1 |
| Fukuda, H; Goto, M; Hasebe, Y; Kaneko, T; Kato, K | 1 |
| Beani, L; Bianchi, C; Tanganelli, S | 1 |
| Buu, NT; Duhaime, J; Kuchel, O | 1 |
| Waszczak, BL | 1 |
| Brody, LE; Jacobs, R; Jones, EA; Pappas, SC; Schafer, DF | 1 |
| Kodaira, R; Nagatani, T; Sugihara, T | 1 |
| Acs, Z; Makara, GB; Stark, E | 1 |
| Haddox, VG; Menon, MK; Vivonia, CA | 1 |
| Levine, AS; Morley, JE | 1 |
| Back, KC; George, ME; Pinkerton, MK | 1 |
| Petersen, EN; Scheel-Krüger, J | 1 |
| Artaud, F; Bourgoin, S; Cesselin, F; Glowinski, J; Hamon, M | 1 |
| Cortese, I; Cuomo, V; Siro-Brigiani, G | 1 |
| Ashton, D; Geerts, R; Leysen, JE; Waterkeyn, C | 1 |
| Fukuda, H; Kaneko, T; Ono, H | 1 |
| Clark, WG; Menon, MK; Vivonia, C | 1 |
| Duka, T; Herz, A; Wüster, M | 1 |
| Chieli, T; Cocchi, D; Fregnan, GB; Müller, EE | 1 |
| Desarmenien, M; Feltz, P; Lamour, Y | 1 |
| Forchetti, CM; Meek, JL | 1 |
| Kaneto, H; Rahman, AF; Takahashi, M | 1 |
| Iwasaki, T; Nakagawa, Y | 2 |
| Hiemke, C; Jussofie, A; Schmiz, A | 1 |
| Angelides, KJ; Duffy, S; Fraser, DD; Kettenmann, H; MacVicar, BA; Perez-Velazquez, JL | 1 |
| Amabeoku, G; Chikuni, O | 1 |
| Golovko, AI; Kliuntina, TV; Sofronov, GA | 1 |
| Ha, JH; Kim, WJ; Lee, KY | 1 |
| Lennon, VA; Parkman, HP; Stapelfeldt, WH; Szurszewski, JH; Williams, CL | 1 |
| Ho, IK; Ito, Y | 1 |
| Nielsen, M; Witt, MR | 1 |
| Korpi, ER; Seeburg, PH | 1 |
| Amico-Roxas, M; Caruso, A; Cutuli, VM; de Bernardis, E; Lucenti, A; Villari, L | 1 |
| Hikida, M; Inomata, N; Masukawa, Y; Nishiki, K | 1 |
| el Manira, A; Grillner, S; Matsushima, T; Tegnér, J | 1 |
| Ishima, T; Iwasaki, T; Kimura, K; Nakagawa, Y | 1 |
| Chikai, T; Oishi, R; Saeki, K | 1 |
| Misawa, M; Motegi, H; Suzuki, T | 1 |
| Dowling, JE; Qian, H | 1 |
| Kabuto, H; Mori, A; Yokoi, I | 1 |
| Biggio, G; Ghiani, CA; Maciocco, E; Sanna, E; Serra, M; Tuligi, G | 1 |
| Bieger, D; Hockman, CH; Weerasuriya, A | 1 |
| Bonanno, G; Raiteri, M; Schmid, G | 1 |
| Crane, DI; Dodd, PR; McCloskey, A; Smith, ID; Thomas, GJ | 1 |
| Fukura, H; Igarashi, M; Komiya, Y | 1 |
| Fukuda, H; Ito, Y; Kobayashi, M; Segawa, K | 1 |
| Dodd, PR; Harper, CG; Johnston, GA; Kril, JJ; Thomas, GJ; Watson, WE | 1 |
| Dodd, PR | 1 |
| Liljequist, S; Pokk, P; Zharkovsky, A | 1 |
| Dalvi, A; Rodgers, RJ | 1 |
| Obata, K | 1 |
| Barros, HM; Manitiu, A; Miczek, KA; Vivian, JA | 1 |
| Benke, D; Michel, C; Mohler, H | 1 |
| Ashby, CR; Katsumori, H; Minabe, Y; Osawa, M | 1 |
| Biggio, G; Concas, A; Floris, S; Follesa, P; Mostallino, MC; Tuligi, G | 1 |
| Akhondzadeh, S; Stone, TW | 1 |
| Chistina Grobin, A; Devaud, LL; Inglefield, JR; Morrow, AL; Schwartz-Bloom, RD | 1 |
| Flemström, G; Säfsten, B | 1 |
| Galligan, JJ; Zhou, X | 1 |
| Chen, Z; Fujii, Y; Ishizawa, K; Kamei, C; Okuma, C; Sugimoto, Y | 1 |
| Berridge, KC; Söderpalm, AH | 1 |
| Bidziński, A; Członkowska, AI; Płaźnik, A; Siemiatkowski, M; Sienkiewicz-Jarosz, H | 1 |
| Ansaldo, MA; Fedele, E; Raiteri, M; Varnier, G | 1 |
| Lin, J; Nordholm, AF; Pancrazio, JJ; Ritchie, GD; Rossi, J; Stenger, DA | 1 |
| Germane, S; Klusa, V; Opmane, B; Svirskis, S; Wikberg, JE | 1 |
| Baufreton, J; Bioulac, B; Dovero, S; Dufy, B; Garret, M; Taupignon, A | 1 |
| Hodge, CW; Homanics, GE; Khisti, RT; Kralic, JE; Morrow, AL; O'Buckley, TK | 1 |
| Akhondzadeh, S; Kashani, L; Mohammadi, MR | 1 |
| Baur, R; Sigel, E | 1 |
| Cardin, JA; Schmidt, MF | 1 |
| Chopde, CT; Hirani, K; Jain, NS | 1 |
| Carta, A; Chopde, CT; Kokare, DM; Patole, AM; Subhedar, NK | 1 |
| Aas, P; Enger, S; Myhrer, T; Nguyen, NH | 1 |
| Jembrek, MJ; Pericić, D; Strac, DS; Vlainić, J | 1 |
| Dean, B; McLeod, MC; Sundram, S | 1 |
| Jazvinsćak Jembrek, M; Pericić, D; Svob Strac, D; Vlainić, J | 1 |
| Cho, JH; Choi, BJ; Choi, IS; Han, JW; Jang, HJ; Jang, IS; Lee, MG; Nakamura, M; Park, HM | 1 |
| Kawaguchi, M; Okubo, M | 1 |
| Brandão, ML; Cabral, A; Nobre, MJ | 1 |
| Akaike, N; Iwata, S; Shin, MC; Wakita, M; Xie, DJ | 1 |
| Arnold, LA; Chen, Q; Cook, JM; Emala, CW; Ionescu-Zanetti, C; Johnson, J; Smith, S; Wang, ZJ; Yim, PD; Yuan, N | 1 |
| Davies, PA; Deeb, TZ; Frost, GD; Moss, SJ; Nakamura, Y | 1 |
| Grauer, M; Jabs, R; Passlick, S; Schäfer, C; Seifert, G; Steinhäuser, C | 1 |
| Denman, RB; Merz, G; Sung, YJ; Xie, W | 1 |
| Allain, L; Gouzer, G; Shinoe, T; Specht, CG; Triller, A | 1 |
| Aguilar, BL; Forcelli, PA; Malkova, L; Wellman, LL | 1 |
| Gold, MS; Loeza-Alcocer, E | 1 |
4 review(s) available for muscimol and diazepam
| Article | Year |
|---|---|
Modulation of benzodiazepine binding site sensitivity.
Topics: Aminooxyacetic Acid; Animals; Anti-Anxiety Agents; Binding Sites; Diazepam; Drug Interactions; Electrophysiology; Humans; Kinetics; Muscimol; Phenytoin | 1979 |
Mechanism of action of benzodiazepines - the GABA hypothesis.
Topics: Acetylcholine; Animals; Benzodiazepines; Brain; Catecholamines; Cerebellum; Diazepam; gamma-Aminobutyric Acid; Ganglia, Autonomic; Glutamates; Glycine; Guanosine Monophosphate; Humans; Muscimol; Neurons; Receptors, Neurotransmitter; Serotonin | 1978 |
Multilevel transneuronal degeneration after brain damage. Behavioral events and effects of anticonvulsant gamma-aminobutyric acid-related drugs.
Topics: Animals; Atrophy; Behavior, Animal; Cerebrovascular Disorders; Corpus Striatum; Diazepam; gamma-Aminobutyric Acid; Muscimol; Neural Pathways; Neurons; Rats; Substantia Nigra; Thalamus | 1990 |
Drugs acting on amino acid neurotransmitters.
Topics: Acoustic Stimulation; Amino Acids; Animals; Chemical Phenomena; Chemistry; Diazepam; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Humans; Hypoxia; Imidazoles; Isoxazoles; Mice; Mice, Inbred DBA; Muscimol; Myoclonus; Neurotransmitter Agents; Papio; Rats; Rats, Inbred Strains; Seizures; Valproic Acid | 1986 |
232 other study(ies) available for muscimol and diazepam
| Article | Year |
|---|---|
A novel class of "GABAergic" agents: 1-aryl-3-(aminoalkylidene)oxindoles.
Topics: 3-Mercaptopropionic Acid; Animals; Flunitrazepam; Indoles; Male; Mice; Receptors, GABA-A; Structure-Activity Relationship; Sulfhydryl Compounds | 1989 |
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine and analogues as A2A adenosine receptor antagonists. Design, synthesis, and pharmacological characterization.
Topics: Adenine; Adenosine A2 Receptor Antagonists; Animals; Cell Line; Cricetinae; Cricetulus; Drug Design; Humans; Imidazoles; Male; Models, Molecular; Motor Activity; Purines; Radioligand Assay; Rats; Rats, Inbred F344; Structure-Activity Relationship; Triazoles | 2005 |
[Effects of muscimol and diazepam: a comparative study on behavioral inhibiton induced by novelty, punishment, and nonreward (author's transl)].
Topics: Animals; Behavior, Animal; Conditioning, Operant; Diazepam; Environment; Feeding Behavior; Male; Muscimol; Oxazoles; Punishment; Rats; Reward | 1979 |
Effects of diazepam and muscimol on GABA-mediated neurotransmission: interactions with inosine and nicotinamide.
Topics: Animals; Corpus Striatum; Diazepam; Drug Interactions; Female; gamma-Aminobutyric Acid; Globus Pallidus; Inosine; Muscimol; Niacinamide; Oxazoles; Rats; Synaptic Transmission; Time Factors | 1979 |
Stimulation of benzodiazepine receptor binding by gamma-aminobutyric acid.
Topics: Animals; Bicuculline; Brain; Cerebral Cortex; Diazepam; gamma-Aminobutyric Acid; Kinetics; Membranes; Muscimol; Rats; Receptors, Drug | 1979 |
Identification of diazepam binding in intack animals.
Topics: Aminooxyacetic Acid; Animals; Benzodiazepines; Binding, Competitive; Brain; Diazepam; Male; Muscimol; Rats; Time Factors | 1979 |
Enhancement of the binding of 3H-diazepam to rat brain membranes in vitro by SQ 20009, A novel anxiolytic, gamma-aminobutyric acid (GABA) and muscimol.
Topics: Animals; Bicuculline; Brain; Diazepam; Etazolate; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Membranes; Muscimol; Nicotinic Acids; Oxazoles; Picrotoxin; Rats; Stimulation, Chemical | 1979 |
Partial agonists for brain GABA/benzodiazepine receptor complex.
Topics: Animals; Benzodiazepines; Bicuculline; Brain; Crotonates; Diazepam; GABA Antagonists; gamma-Aminobutyric Acid; Imidazoles; Isoxazoles; Muscimol; Piperidines; Rats; Receptors, Drug; Sulfonic Acids | 1979 |
The GABA agonist THIP a muscimol analogue, does not interfere with the benzodiazepine binding site on rats cortical membranes.
Topics: Animals; Cerebral Cortex; Diazepam; gamma-Aminobutyric Acid; Imidazoles; In Vitro Techniques; Isonicotinic Acids; Male; Muscimol; Oxazoles; Rats; Receptors, Drug; Taurine | 1979 |
[Role of the GABA-ergic systems of the brain in manifesting the activating effect of diazepam].
Topics: Animals; Bicuculline; Brain; Diazepam; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Motor Activity; Muscimol; Rats; Receptors, Drug; Self Stimulation | 1979 |
Symmetric bilateral changes in dopamine release from the caudate nuclei of the cat induced by unilateral nigral application of glycine and GABA-related compounds.
Topics: Animals; Cats; Caudate Nucleus; Diazepam; Dominance, Cerebral; Dopamine; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Muscimol; Neural Pathways; Picrotoxin; Potassium; Strychnine; Substantia Nigra; Tyrosine | 1979 |
A comparative study of the effects of muscimol and diazepam on the recall of noxious events.
Topics: Animals; Avoidance Learning; Diazepam; Dissociative Disorders; gamma-Aminobutyric Acid; Humans; Male; Memory; Mental Recall; Muscimol; Oxazoles; Rats | 1979 |
Effects of central GABA receptor agonism and antagonism on evoked diencephalic cardiovascular responses.
Topics: Animals; Bicuculline; Cats; Diazepam; Diencephalon; Electric Stimulation; gamma-Aminobutyric Acid; Hemodynamics; Muscimol; Receptors, Drug; Sympathetic Nervous System | 1978 |
Influence of GABA receptor agonists and antagonists on the binding of 3H-diazepam to the benzodiazepine receptor.
Topics: Animals; Benzodiazepines; Bicuculline; Brain; Diazepam; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Rats; Receptors, Drug | 1978 |
gamma-Aminobutyric acidA receptor pharmacology in rat cerebral cortical synaptoneurosomes.
Topics: Animals; Benzodiazepines; Cerebral Cortex; Diazepam; Male; Muscimol; Nipecotic Acids; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes; Tiagabine; Tritium | 1992 |
Effects of some GABAergic agents on quinine-induced seizures in mice.
Topics: Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Diazepam; Male; Mice; Mice, Inbred Strains; Muscimol; Phenobarbital; Phenytoin; Quinine; Receptors, GABA-A; Seizures | 1992 |
Alfaxalone, pentobarbital and diazepam potentiate gamma-aminobutyric acid-induced depolarizations in single myenteric neurons of guinea pig intestine.
Topics: Anesthetics; Animals; Diazepam; Drug Synergism; gamma-Aminobutyric Acid; Guinea Pigs; Hydrocortisone; Intestines; Male; Membrane Potentials; Muscimol; Pentobarbital; Pregnanediones; Receptors, GABA-A | 1992 |
Immortalized hypothalamic GT1-7 neurons express functional gamma-aminobutyric acid type A receptors.
Topics: Anesthetics; Animals; Barbiturates; Base Sequence; Bicuculline; Cell Line, Transformed; Cell Membrane; Chloride Channels; Diazepam; Electrophysiology; Flunitrazepam; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation; Hypothalamus; Membrane Proteins; Mice; Molecular Sequence Data; Muscimol; Neurons; Peptides; Polymerase Chain Reaction; Receptors, GABA-A; RNA, Messenger; Sensitivity and Specificity; Steroids; Tritium; Tumor Cells, Cultured; Zinc | 1992 |
Ro 15-4513 binding to GABAA receptors: subunit composition determines ligand efficacy.
Topics: Animals; Azides; Benzodiazepines; Binding, Competitive; Brain; Cerebellum; Diazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Ligands; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1992 |
[Effects of GABA antagonist-induced seizures on 3H-muscimol and 3H-diazepam binding in the rat striatum].
Topics: Animals; Bicuculline; Binding Sites; Corpus Striatum; Diazepam; GABA Antagonists; Male; Muscimol; Picrotoxin; Rats; Receptors, GABA-A; Seizures; Tritium | 1992 |
[Effects of agonists and antagonists of benzodiazepine, GABA and NMDA receptors, on caffeine-induced seizures in mice].
Topics: Animals; Baclofen; Benzodiazepines; Caffeine; Diazepam; Dizocilpine Maleate; Flumazenil; Male; Mice; Muscimol; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic; Seizures | 1992 |
Naloxone-induced hypoalgesia: lack of involvement of the GABA-benzodiazepine receptor complex.
Topics: Analgesia; Animals; Baclofen; Bicuculline; Diazepam; Male; Muscimol; Naloxone; Pain Measurement; Rats; Rats, Wistar; Receptors, GABA-A | 1992 |
Sex differences in sensitivity to pentylenetetrazol but not in GABAA receptor binding.
Topics: Anesthetics; Animals; Anticonvulsants; Autoradiography; Benzodiazepinones; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Convulsants; Diazepam; Electroshock; Ethanol; Female; Flunitrazepam; Male; Muscimol; Orchiectomy; Ovariectomy; Pentylenetetrazole; Pregnanediones; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Seizures; Sex Characteristics | 1992 |
Regulation of somatostatin synthesis by GABAA receptor stimulation in mouse brain.
Topics: Animals; Cerebral Cortex; Corpus Striatum; Diazepam; Gene Expression Regulation; Hypothalamus; Male; Mice; Muscimol; Protein Precursors; Receptors, GABA-A; RNA, Messenger; Somatostatin; Stimulation, Chemical | 1992 |
Effect of thiol group modification on ion flux and ligand binding properties of the GABAA-benzodiazepine receptor chloride channel complex.
Topics: Animals; Chlorides; Chlorine; Diazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Male; Mice; Mice, Inbred ICR; Muscimol; Radioisotopes; Receptors, GABA-A; Sulfhydryl Compounds; Sulfhydryl Reagents | 1992 |
gamma-Aminobutyric acid-induced response in rat dissociated paratracheal ganglion cells.
Topics: Animals; Chlorides; Diazepam; Drug Synergism; Electric Conductivity; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia; Muscimol; Pentobarbital; Rats; Rats, Inbred Strains; Trachea | 1992 |
Involvement of GABAergic mechanisms in chloroquine-induced seizures in mice.
Topics: Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Chloroquine; Diazepam; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Phenobarbital; Seizures | 1992 |
gamma-Aminobutyric acid-activated chloride channels in rats selectively bred for differential acute sensitivity to alcohol.
Topics: Alcohol Drinking; Animals; Chloride Channels; Diazepam; Female; Flunitrazepam; gamma-Aminobutyric Acid; Membrane Proteins; Muscimol; Pentobarbital; Phenobarbital; Phenotype; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Selection, Genetic | 1991 |
Modulation of GABAB receptors by chronic treatment with clonazepam.
Topics: Animals; Baclofen; Brain; Clonazepam; Diazepam; Male; Muscimol; Radioligand Assay; Rats; Rats, Inbred WKY; Receptors, GABA-A | 1991 |
GABA/BZ-and NMDA-receptor interaction in digoxin-induced convulsions in rats.
Topics: Animals; Baclofen; Diazepam; Digoxin; Dizocilpine Maleate; Female; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Muscimol; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Salts; Seizures | 1991 |
Effect of ethanol and DSIP on the 36Cl-flux in synaptosomal vesicles.
Topics: Animals; Biological Transport; Cerebral Cortex; Chlorides; Delta Sleep-Inducing Peptide; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Membrane Lipids; Muscimol; Rats; Receptors, GABA-A; Synaptosomes; Temperature | 1991 |
GABAmimetic agents display anxiolytic-like effects in the social interaction and elevated plus maze procedures.
Topics: Aminooxyacetic Acid; Animals; Anti-Anxiety Agents; Conflict, Psychological; Diazepam; Exploratory Behavior; gamma-Aminobutyric Acid; Isonicotinic Acids; Isoxazoles; Male; Muscimol; Rats; Rats, Inbred Strains; Social Behavior; Valproic Acid | 1991 |
Role of cGMP in the mechanism of anxiolytic activity of U-78875.
Topics: Animals; Anti-Anxiety Agents; Binding, Competitive; Brain Chemistry; Carbolines; Cerebellum; Convulsants; Cyclic GMP; Diazepam; Dose-Response Relationship, Drug; Electroshock; Flunitrazepam; Male; Mice; Muscimol; Oxadiazoles; Quinoxalines; Rats; Rats, Inbred Strains; Stress, Psychological | 1991 |
Melatonin interaction with the benzodiazepine-GABA receptor complex in the CNS.
Topics: Animals; Anti-Anxiety Agents; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cerebral Cortex; Chlorides; Diazepam; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Ion Channels; Melatonin; Muscimol; Prosencephalon; Rats; Receptors, GABA-A; Serotonin; Synaptosomes | 1991 |
Effects of diazepam on nociception in rats.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Benzomorphans; Chlordiazepoxide; Convulsants; Diazepam; Drug Interactions; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Spinal; Male; Midazolam; Muscimol; Naloxone; Narcotic Antagonists; Nociceptors; Pain Measurement; Rats; Rats, Inbred Strains; Time Factors | 1991 |
Muscimol-associated changes in local cerebral glucose use following chronic diazepam administration.
Topics: Animals; Autoradiography; Behavior, Animal; Blood Glucose; Blood Pressure; Brain Chemistry; Deoxyglucose; Depression, Chemical; Diazepam; Glucose; Male; Muscimol; Rats | 1991 |
The contribution of endogenous benzodiazepine receptor ligands to the pathogenesis of hepatic encephalopathy.
Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chromatography, High Pressure Liquid; Diazepam; Flumazenil; Hepatic Encephalopathy; Kinetics; Ligands; Male; Mass Spectrometry; Muscimol; Peripheral Nerves; Rabbits; Radioligand Assay; Receptors, GABA-A; Sulfur Radioisotopes | 1991 |
Pentobarbital selectively blocks supraspinal morphine analgesia. Evidence for GABAA receptor involvement.
Topics: Analgesia; Animals; Diazepam; Drug Synergism; Injections, Intraventricular; Injections, Spinal; Male; Morphine; Muscimol; Pentobarbital; Phenobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Spinal Cord | 1990 |
Effects of GABA and anxiolytics on the single unit discharge of suprachiasmatic neurons in rat hypothalamic slices.
Topics: Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Baclofen; Bicuculline; Diazepam; Flunitrazepam; gamma-Aminobutyric Acid; Hypothalamus; In Vitro Techniques; Muscimol; Neurons; Piperazines; Rats; Receptors, GABA-A; Suprachiasmatic Nucleus | 1990 |
Adaptative changes in two indices of enkephalin neuron activity in mouse striatum following GABAergic stimulation.
Topics: Animals; Corpus Striatum; Diazepam; Enkephalins; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Oligopeptides; Protein Precursors; Receptors, GABA-A; RNA, Messenger | 1990 |
(+)-Hydrastine, a potent competitive antagonist at mammalian GABAA receptors.
Topics: Acetylcholine; Alkaloids; Animals; Baclofen; Benzylisoquinolines; Bicuculline; Binding, Competitive; Brain Chemistry; Convulsants; Diazepam; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Membranes; Muscimol; Muscle, Smooth; Muscle, Smooth, Vascular; Rats; Receptors, GABA-A; Stereoisomerism | 1990 |
Increased gamma-aminobutyric acid receptor function in the cerebral cortex of myoclonic calves with an hereditary deficit in glycine/strychnine receptors.
Topics: Animals; Benzodiazepines; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cerebral Cortex; Chloride Channels; Chlorides; Chlorine; Diazepam; Female; gamma-Aminobutyric Acid; Ligands; Male; Membrane Proteins; Muscimol; Myoclonus; Radioisotopes; Receptors, GABA-A; Receptors, Glycine; Receptors, Neurotransmitter; Synaptic Membranes | 1990 |
Pharmacological characteristics of two different types of inhibitory GABA receptors on Achatina fulica neurones.
Topics: Animals; Baclofen; Bicuculline; Crotonates; Diazepam; Dibenzazepines; Electrophysiology; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Muscimol; Neurons; Pentobarbital; Picrotoxin; Receptors, GABA-A; Snails | 1990 |
Species dependent dual modulation of the benzodiazepine/GABA receptor chloride channel by dihydroergosine.
Topics: Animals; Bicuculline; Brain; Chloride Channels; Diazepam; Ergotamines; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Proteins; Mice; Mice, Inbred CBA; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures; Species Specificity | 1990 |
Enkephalin biosynthesis and release in mouse striatum are inhibited by GABA receptor stimulation: compared changes in preproenkephalin mRNA and Tyr-Gly-Gly levels.
Topics: Aminooxyacetic Acid; Animals; Corpus Striatum; Diazepam; Enkephalins; Flumazenil; Kinetics; Leucine; Male; Mice; Muscimol; Oligopeptides; Protein Precursors; Receptors, GABA-A; RNA, Messenger | 1990 |
Possible involvement of low and high affinity GABA receptors in the chloride influx into synaptosomes.
Topics: 4-Aminobutyrate Transaminase; Aldehyde Oxidoreductases; Animals; Chlorides; Diazepam; gamma-Aminobutyric Acid; Ion Channels; Muscimol; Phenobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes | 1986 |
GABAergic modulation of a substance P-mediated reflex of slow time course in the isolated rat spinal cord.
Topics: Animals; Baclofen; Bicuculline; Diazepam; Electrophysiology; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Rats; Rats, Inbred Strains; Reflex; Spinal Cord; Substance P | 1987 |
Genetic selection for benzodiazepine ataxia produces functional changes in the gamma-aminobutyric acid receptor chloride channel complex.
Topics: Animals; Ataxia; Chlorides; Diazepam; Ethanol; Flunitrazepam; Ion Channels; Isoxazoles; Mice; Muscimol; Phenobarbital; Receptors, GABA-A; Time Factors | 1988 |
Decreased sensitivity to benzodiazepine receptor agonists and increased sensitivity to inverse agonists following chronic treatments: evidence for separate mechanisms.
Topics: Animals; Anti-Anxiety Agents; Appetite Depressants; Benzodiazepines; Carbolines; Chlorides; Diazepam; Drug Interactions; Drug Tolerance; Exploratory Behavior; Ion Channels; Kindling, Neurologic; Locomotion; Lorazepam; Mice; Muscimol; Pentylenetetrazole; Rats; Receptors, GABA-A | 1988 |
Kinetic and pharmacological properties of the GABA-induced chloride current in Aplysia neurones: a 'concentration clamp' study.
Topics: Animals; Aplysia; beta-Alanine; Chlorides; Diazepam; gamma-Aminobutyric Acid; Ion Channels; Kinetics; Muscimol; Neurons; Pentobarbital | 1988 |
The GABA/benzodiazepine receptor chloride channel complex during repeated episodes of physical ethanol dependence in the rat.
Topics: Alcoholism; Animals; Chlorides; Diazepam; Ion Channels; Male; Muscimol; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, GABA-A; Substance Withdrawal Syndrome; Sulfur Radioisotopes | 1988 |
Macrolide compounds, ivermectin and milbemycin D, stimulate chloride channels sensitive to GABAergic drugs in cultured chick spinal neurons.
Topics: Animals; Anti-Bacterial Agents; Bicuculline; Cells, Cultured; Chick Embryo; Chlorides; Diazepam; gamma-Aminobutyric Acid; Ion Channels; Ivermectin; Lactones; Macrolides; Membrane Potentials; Muscimol; Neurons; Picrotoxin; Sesterterpenes; Spinal Cord | 1989 |
Estrogen modulation of the gamma-aminobutyric acid receptor complex in the central nervous system of rat.
Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Diazepam; Dose-Response Relationship, Drug; Estrogens; Female; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; RNA; Seizures | 1988 |
Both systemic and local administration of benzodiazepine agonists inhibit the in vivo release of 5-HT from ventral hippocampus.
Topics: Animals; Benzodiazepines; Carbolines; Chromatography, High Pressure Liquid; Dialysis; Diazepam; Flumazenil; Flurazepam; Hippocampus; Hydroxyindoleacetic Acid; Ion Channels; Male; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Serotonin | 1989 |
Diazepam sensitizes mice to FG 7142 and reduces muscimol-stimulated 36Cl- flux.
Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carbolines; Chlorides; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Ion Channels; Kindling, Neurologic; Mice; Mice, Inbred ICR; Muscimol | 1989 |
Postnatal evolution of the gamma-aminobutyric acid/benzodiazepine receptor complex in a model of inherited epilepsy: the quaking mouse.
Topics: Aging; Animals; Brain; Brain Stem; Cerebellum; Diazepam; Diencephalon; Epilepsy; Flunitrazepam; gamma-Aminobutyric Acid; Mice; Mice, Inbred C57BL; Mice, Quaking; Muscimol; Receptors, GABA-A; Telencephalon | 1989 |
Enhancement of GABAergic transmission by zolpidem, an imidazopyridine with preferential affinity for type I benzodiazepine receptors.
Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Diazepam; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Male; Muscimol; Pyridines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptic Transmission; Zolpidem | 1989 |
Evidence that clomethiazole interacts with the macromolecular GABA A-receptor complex in the central nervous system and in the anterior pituitary gland.
Topics: Animals; Central Nervous System; Chlormethiazole; Diazepam; gamma-Aminobutyric Acid; Hypothalamus; In Vitro Techniques; Indicators and Reagents; Male; Muscimol; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptic Transmission | 1989 |
GABA[A] receptor level changes in female hamster forebrain following in vivo estrogen progesterone and benzodiazepine treatment: a quantitative autoradiography analysis.
Topics: Animals; Autoradiography; Benzodiazepines; Cricetinae; Diazepam; Estradiol; Female; Flumazenil; Frontal Lobe; Muscimol; Ovariectomy; Progesterone; Receptors, GABA-A | 1989 |
36Cl- flux measurements on GABAA receptor-activated chloride exchange. Multiple mechanisms of the chloride channel inactivation.
Topics: Animals; Baclofen; Cerebellum; Chloride Channels; Chlorides; Chlorine; Diazepam; In Vitro Techniques; Membrane Proteins; Muscimol; Neurons; Pertussis Toxin; Radioisotopes; Rats; Receptors, GABA-A; Virulence Factors, Bordetella | 1989 |
Heterogeneity of gamma-aminobutyric acid/benzodiazepine/beta-carboline receptor complex in rat spinal cord.
Topics: Animals; Bicuculline; Binding, Competitive; Carbolines; Cerebellum; Diazepam; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Receptors, GABA-A; Spinal Cord; Synaptic Membranes | 1988 |
Melatonin enhancement of [3H]-gamma-aminobutyric acid and [3H]muscimol binding in rat brain.
Topics: Animals; Brain; Diazepam; Dose-Response Relationship, Drug; Freezing; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Melatonin; Muscimol; Octoxynol; Polyethylene Glycols; Rats; Rats, Inbred Strains; Receptors, GABA-A; Tritium | 1988 |
Benzodiazepines and barbiturate potentiate the pre- and postsynaptic gamma-aminobutyric acid (GABA)A receptor-mediated response in the enteric nervous system of guinea pig small intestine.
Topics: Acetylcholine; Animals; Barbiturates; Benzodiazepines; Clonazepam; Diazepam; Female; Flumazenil; Guinea Pigs; Intestine, Small; Male; Muscimol; Pentobarbital; Potassium; Receptors, GABA-A | 1988 |
GABAA receptor populations bind agonists and antagonists differentially and with opposite affinities.
Topics: Affinity Labels; Androstanes; Animals; Azasteroids; Brain; Diazepam; Diazonium Compounds; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Photochemistry; Pyridazines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sulfanilic Acids; Synaptic Membranes | 1988 |
The ontogeny of GABA receptors and glutamic acid decarboxylase in regions of the rat brain. Effect of prenatal exposure to diazepam.
Topics: Animals; Brain; Diazepam; Female; Glutamate Decarboxylase; Muscimol; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Receptors, GABA-A | 1988 |
Involvement of GABAergic systems and benzodiazepine receptors in the jumping behavior induced by harmine and apomorphine in rats.
Topics: Alkaloids; Animals; Apomorphine; Brain; Diazepam; Flumazenil; Harmine; Hydroxydopamines; Male; Motor Activity; Muscimol; Oxidopamine; Pyridines; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1988 |
Delta-guanidinovaleric acid as an endogenous and specific GABA-receptor antagonist: electroencephalographic study.
Topics: Animals; Arginine; Cerebral Cortex; Diazepam; Electroencephalography; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures; Valerates | 1987 |
Behavioral differences in an elevated plus-maze: correlation between anxiety and decreased number of GABA and benzodiazepine receptors in mouse cerebral cortex.
Topics: Animals; Anxiety; Brain; Carbolines; Cerebral Cortex; Diazepam; Exploratory Behavior; Flunitrazepam; Male; Mice; Muscimol; Receptors, GABA-A | 1988 |
Enhanced benzodiazepine responsiveness in rats with increased cholinergic function.
Topics: Animals; Benzodiazepines; Corpus Striatum; Diazepam; Dose-Response Relationship, Drug; Hippocampus; Motor Activity; Muscimol; Oxotremorine; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Muscarinic | 1988 |
Photoaffinity labeling of the GABAA receptor with [3H]muscimol.
Topics: Affinity Labels; Animals; Baclofen; Diazepam; Glutamates; Glutamic Acid; Kinetics; Male; Molecular Weight; Muscimol; Oxazoles; Photochemistry; Rats; Rats, Inbred Strains; Receptors, GABA-A; Spectrophotometry, Ultraviolet | 1985 |
Benzodiazepines enhance the muscimol-dependent activation of phospholipase A2 in glioma C6 cells.
Topics: Animals; Anti-Anxiety Agents; Arachidonic Acid; Arachidonic Acids; Cell Line; Chromatography, High Pressure Liquid; Diazepam; Drug Interactions; Enzyme Activation; Glioma; Muscimol; Neuroglia; Oxazoles; Phospholipases; Phospholipases A; Phospholipases A2; Prostaglandin D2; Prostaglandins D; Rats; Receptors, GABA-A | 1985 |
Involvement of noradrenaline in potentiation of the head-twitch response by GABA-related drugs.
Topics: Adrenergic beta-Antagonists; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Brain Chemistry; Catecholamines; Diazepam; Dopamine; Drug Synergism; gamma-Aminobutyric Acid; Male; Methoxydimethyltryptamines; Metoprolol; Mice; Muscimol; Norepinephrine; Pentobarbital; Picrotoxin; Stereotyped Behavior; Taurine | 1986 |
Kindling-induced changes in EEG recorded during stimulation from the site of stimulation. III. Direct pharmacological manipulations of the kindled amygdala.
Topics: 2-Amino-5-phosphonovalerate; Amygdala; Animals; Atropine; Baclofen; Diazepam; Electroencephalography; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Muscimol; Neural Inhibition; Rats; Rats, Inbred Strains; Reaction Time; Receptors, GABA-A; Valine | 1987 |
Differential mechanisms involved in the anticonflict action of benzodiazepines injected into the central amygdala and mammillary body.
Topics: Amygdala; Animals; Anti-Anxiety Agents; Atropine; Conflict, Psychological; Diazepam; gamma-Aminobutyric Acid; Male; Mammillary Bodies; Microinjections; Muscimol; Punishment; Rats; Rats, Inbred Strains | 1987 |
Foot-shock stress and anxiogenic beta-carbolines increase t-[35S]butylbicyclophosphorothionate binding in the rat cerebral cortex, an effect opposite to anxiolytics and gamma-aminobutyric acid mimetics.
Topics: Animals; Anti-Anxiety Agents; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Carbolines; Cell Membrane; Cerebral Cortex; Convulsants; Diazepam; Electroshock; GABA Antagonists; gamma-Aminobutyric Acid; Kinetics; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stress, Physiological | 1988 |
Discriminative-stimulus effects of midazolam in squirrel monkeys: comparison with other drugs and antagonism by Ro 15-1788.
Topics: Animals; Azabicyclo Compounds; Barbital; Benzodiazepines; Benzodiazepinones; Buspirone; Caffeine; Chlordiazepoxide; Cinanserin; Clozapine; Conditioning, Operant; Cyproheptadine; Diazepam; Diphenhydramine; Discrimination Learning; Electroshock; Flumazenil; Male; Midazolam; Muscimol; Nordazepam; Pentobarbital; Piperazines; Pyridazines; Pyrimidines; Saimiri; Tripelennamine | 1985 |
Modulation of [3H]diazepam binding in rat cortical membranes by GABAA agonists.
Topics: Androstanes; Animals; Azasteroids; Bicuculline; Cell Membrane; Cerebral Cortex; Diazepam; GABA Antagonists; gamma-Aminobutyric Acid; Imidazoles; Isonicotinic Acids; Isoxazoles; Muscimol; Piperidines; Rats; Receptors, GABA-A; Taurine | 1985 |
Radiation inactivation studies of the benzodiazepine/gamma-aminobutyric acid/chloride ionophore receptor complex.
Topics: Animals; Barbiturates; Benzodiazepines; Benzodiazepinones; Binding Sites; Brain; Carbolines; Cell Membrane; Chlorides; Diazepam; Flumazenil; Flunitrazepam; Ionophores; Male; Molecular Weight; Muscimol; Picrotoxin; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1985 |
Reduction of GABAB receptor binding induced by climbing fiber degeneration in the rat cerebellum.
Topics: Animals; Baclofen; Cerebellum; Cerebral Cortex; Diazepam; Male; Muscimol; Olivary Nucleus; Pyridines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptic Membranes | 1985 |
Benzodiazepine/gamma-aminobutyric acid receptor deficit in the midbrain of the seizure-susceptible gerbil.
Topics: Animals; Bicuculline; Diazepam; Disease Models, Animal; Flunitrazepam; Gerbillinae; Mesencephalon; Muscimol; Pentobarbital; Receptors, GABA-A; Seizures | 1985 |
GABA agonists. Resolution, absolute stereochemistry, and enantioselectivity of (S)-(+)- and (R)-(-)-dihydromuscimol.
Topics: Animals; Bicuculline; Brain; Cats; Chemical Phenomena; Chemistry; Diazepam; gamma-Aminobutyric Acid; Isoxazoles; Molecular Conformation; Muscimol; Neurons; Oxazolidinones; Piperidines; Rats; Receptors, GABA-A; Spinal Cord; Stereoisomerism; Structure-Activity Relationship; Synaptic Membranes | 1985 |
Anticonvulsant activity of piperidinol and (dialkylamino)alkanol esters.
Topics: Amino Alcohols; Animals; Anticonvulsants; Ataxia; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Diazepam; Electroshock; Esters; Muscimol; Pentylenetetrazole; Phenytoin; Piperidines; Rats; Receptors, GABA-A; Structure-Activity Relationship | 1986 |
The enhancement of diazepam and muscimol binding by pentobarbital and (+)-etomidate: size of the molecular arrangement estimated by electron irradiation inactivation of rat cortex.
Topics: Animals; Cerebral Cortex; Diazepam; Etomidate; gamma-Aminobutyric Acid; In Vitro Techniques; Molecular Weight; Muscimol; Pentobarbital; Rats; Receptors, GABA-A | 1986 |
gamma-Aminobutyric acid receptor ionophore complexes: differential effects of deltamethrin, dichlorodiphenyltrichloroethane, and some novel insecticides in a rat brain membrane preparation.
Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; DDT; Diazepam; Insecticides; Ionophores; Male; Muscimol; Nitriles; Pyrethrins; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1987 |
Pyrethroid insecticides and radioligand displacement from the GABA receptor chloride ionophore complex.
Topics: Animals; Binding, Competitive; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Diazepam; Flunitrazepam; Male; Muscimol; Nitriles; Permethrin; Pyrethrins; Rats; Receptors, GABA-A | 1987 |
Interaction of the pesticide chlordimeform with adrenergic receptors in mouse brain: an in vitro study.
Topics: Amidines; Animals; Brain Chemistry; Chlorphenamidine; Clonidine; Diazepam; Dihydroalprenolol; Dioxanes; In Vitro Techniques; Kinetics; Male; Mice; Muscimol; Proteins; Quinuclidinyl Benzilate; Receptors, Adrenergic; Receptors, GABA-A | 1987 |
Interactions of Ro 15-1788, CGS 8216 and diazepam on head-turning in rats.
Topics: Animals; Benzodiazepinones; Diazepam; Drug Interactions; Electric Stimulation; Flumazenil; Head; Male; Movement; Muscimol; Pyrazoles; Rats; Rats, Inbred Strains | 1986 |
Diazepam-induced decrease in histamine turnover in mouse brain.
Topics: Animals; Benzodiazepinones; Brain; Diazepam; Drug Interactions; Flumazenil; Histamine; Male; Methylhistamines; Mice; Muscimol; Pargyline | 1986 |
Interaction between GABAergic neurotransmission and rat hypothalamic corticotropin-releasing hormone secretion in vitro.
Topics: Animals; Baclofen; Corticotropin-Releasing Hormone; Diazepam; gamma-Aminobutyric Acid; Hypothalamus; Male; Muscimol; Organ Culture Techniques; Rats; Rats, Inbred Strains; Serotonin | 1988 |
Inhibition of the voltage-dependent calcium currents in isolated frog sensory neurons by GABA-related agonistic compounds.
Topics: Animals; Baclofen; Barbiturates; Benzodiazepines; Calcium; Diazepam; gamma-Aminobutyric Acid; Ganglia, Spinal; In Vitro Techniques; Muscimol; Neurons, Afferent; Rana catesbeiana; Taurine | 1988 |
Barrel rotation in rats induced by intracerebroventricular bradykinin antagonists.
Topics: Animals; Atropine; Bradykinin; Captopril; Diazepam; Dose-Response Relationship, Drug; Haloperidol; Injections, Intraventricular; Male; Motor Activity; Muscimol; Naloxone; Phenobarbital; Phenytoin; Posture; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1987 |
Benzodiazepine enhancement of gamma-aminobutyric acid-mediated chloride ion flux in rat brain synaptoneurosomes.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Brain; Carbolines; Chlorides; Clonazepam; Diazepam; Drug Synergism; Flurazepam; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rats, Inbred Strains; Synaptosomes | 1988 |
Influence of acoustic stress by noise on gastrointestinal motility in dogs.
Topics: Animals; Corticotropin-Releasing Hormone; Diazepam; Dogs; Gastrointestinal Motility; Hydrocortisone; Muscimol; Naloxone; Noise; Phentolamine; Propranolol; Stomach; Stress, Physiological; Vagus Nerve | 1987 |
Increase of in vitro brain [3H]muscimol binding after L-homocysteine administration to rat.
Topics: Animals; Brain; Diazepam; Homocysteine; Kinetics; Muscimol; Rats | 1987 |
Behavioural and electrocortical changes induced by muscimol in rats withdrawn from chronic treatment with diazepam.
Topics: Animals; Behavior, Animal; Cerebral Cortex; Diazepam; Electroencephalography; Muscimol; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Time Factors | 1987 |
In vivo effects of gamma-aminobutyric acid on the urinary bladder contraction accompanying micturition.
Topics: Aminooxyacetic Acid; Animals; Diazepam; Electric Stimulation; gamma-Aminobutyric Acid; Hexamethonium Compounds; Male; Muscimol; Neurons, Efferent; Picrotoxin; Rats; Rats, Inbred Strains; Semicarbazides; Urinary Bladder; Urination | 1987 |
Asymmetric diffusion into the postsynaptic neuron: an extremely efficient mechanism for removing excess GABA from synaptic clefts on the Deiters' neurone plasma membrane.
Topics: Animals; Biological Transport; Cell Membrane; Diazepam; Diffusion; gamma-Aminobutyric Acid; Mathematics; Muscimol; Neurons; Picrotoxin; Rabbits; Sodium; Synapses; Vestibular Nuclei; Vestibular Nucleus, Lateral | 1986 |
The effect of diazepam upon local cerebral glucose use in the conscious rat.
Topics: Animals; Autoradiography; Brain Chemistry; Deoxy Sugars; Deoxyglucose; Diazepam; Energy Metabolism; gamma-Aminobutyric Acid; Humans; Injections, Intravenous; Isoxazoles; Male; Muscimol; Rats; Rats, Inbred Strains | 1986 |
Diazepam and muscimol blockade of the gastrointestinal motor disturbances induced by acoustic stress in dogs.
Topics: Animals; Diazepam; Dogs; Gastrointestinal Motility; Muscimol; Naloxone; Noise; Stress, Psychological; Sympatholytics | 1986 |
The mesencephalic locomotor region in cat: effects of local applications of diazepam and gamma-aminobutyric acid.
Topics: Animals; Cats; Cerebral Decortication; Diazepam; gamma-Aminobutyric Acid; Locomotion; Muscimol; Picrotoxin; Reaction Time; Reflex; Tegmentum Mesencephali | 1985 |
gamma-Aminobutyric acid- and benzodiazepine-induced modulation of [35S]-t-butylbicyclophosphorothionate binding to cerebellar granule cells.
Topics: Animals; Benzodiazepines; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Carbolines; Cerebellum; Diazepam; gamma-Aminobutyric Acid; Granulocytes; Muscimol; Picrotoxin; Rats; Sulfur Radioisotopes; Temperature | 1985 |
A study on benzodiazepine receptor binding in audiogenic seizure-susceptible rats.
Topics: Acoustic Stimulation; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carbolines; Convulsants; Diazepam; Female; Flunitrazepam; In Vitro Techniques; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures | 1984 |
Decreased convulsant potency of picrotoxin and pentetrazol and enhanced [3H]flunitrazepam cortical binding following stressful manipulations in rats.
Topics: Animals; Anti-Anxiety Agents; Cerebral Cortex; Diazepam; Flunitrazepam; GABA Antagonists; gamma-Aminobutyric Acid; Isoniazid; Male; Muscimol; Pentylenetetrazole; Picrotoxin; Rats; Seizures; Stress, Physiological; Thiosemicarbazones | 1980 |
The role of gamma-aminobutyric acid in acute and chronic neuroleptic action.
Topics: Animals; Antipsychotic Agents; Apomorphine; Diazepam; Dopamine; gamma-Aminobutyric Acid; Humans; Male; Methylphenidate; Mice; Muscimol; Scopolamine; Stereotyped Behavior; Time Factors | 1980 |
Central neurotransmitter mechanisms involved in the control of urinary bladder function. An experimental study in the rat.
Topics: Animals; Brain; Diazepam; Levodopa; Male; Models, Biological; Muscimol; N-Methylscopolamine; Neurotransmitter Agents; Oxotremorine; Rats; Receptors, Cell Surface; Receptors, Dopamine; Receptors, GABA-A; Receptors, Muscarinic; Scopolamine Derivatives; Urinary Bladder | 1980 |
Tofizopam affects binding of [3H]muscimol to gamma-amino-butyric acid receptors in rat and mouse brains.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Binding, Competitive; Brain; Diazepam; Kinetics; Male; Mice; Muscimol; Oxazoles; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter | 1982 |
[Differences in the mechanism of the antihypoxic action of benzodiazepine receptor agonists and muscimol].
Topics: Animals; Anti-Anxiety Agents; Diazepam; Drug Evaluation, Preclinical; gamma-Aminobutyric Acid; Hypoxia; Ligands; Mice; Muscimol; Oxazoles; Receptors, GABA-A | 1984 |
Suriclone, a new anxiolytic of the cyclopyrrolone family: evidence for possible interference with GABAergic systems.
Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Binding, Competitive; Cats; Cerebellum; Chlordiazepoxide; Corpus Striatum; Cyclic GMP; Diazepam; Evoked Potentials; gamma-Aminobutyric Acid; Homovanillic Acid; In Vitro Techniques; Muscimol; Naphthyridines; Nitrazepam; Phenothiazines; Piperazines; Rats; Spinal Cord; Sulfur Compounds | 1984 |
Interactions of taurine and beta-alanine with central nervous system neurotransmitter receptors.
Topics: Alanine; Animals; beta-Alanine; Binding, Competitive; Brain; Diazepam; Dihydroalprenolol; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Membranes; Muscimol; Pineal Gland; Radioligand Assay; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Receptors, Cholinergic; Taurine | 1980 |
Brain nucleotides in naive and handling-habituated rats: differences in levels and drug-sensitivity.
Topics: Animals; Apomorphine; Brain; Cerebellum; Corpus Striatum; Cyclic AMP; Cyclic GMP; Diazepam; Habituation, Psychophysiologic; Haloperidol; Humans; Male; Muscimol; Rats; Stress, Psychological | 1980 |
Studies on benzodiazepine receptors.
Topics: Animals; Benzodiazepines; Binding Sites; Cerebral Cortex; Chlorides; Diazepam; gamma-Aminobutyric Acid; Ligands; Methyltransferases; Muscimol; Neural Inhibition; Phenytoin; Phospholipids; Rats; Receptors, Drug; Receptors, GABA-A; Receptors, Neurotransmitter | 1980 |
Two or more conformations of benzodiazepine receptors depending on GABA receptors and other variables.
Topics: Animals; Benzodiazepines; Bicuculline; Brain; Diazepam; gamma-Aminobutyric Acid; Macromolecular Substances; Male; Muscimol; Piperidines; Rats; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Receptors, Neurotransmitter; Structure-Activity Relationship; Synaptic Membranes | 1980 |
Potentiation by intraventricular muscimol of the anticonflict effect of benzodiazepines.
Topics: Animals; Conditioning, Operant; Conflict, Psychological; Diazepam; Dose-Response Relationship, Drug; Drinking; Eating; Fear; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Muscimol; Oxazoles; Rats; Receptors, Neurotransmitter | 1980 |
GABA and benzodiazepine receptors in the offspring of dams receiving diazepam: ontogenetic studies.
Topics: Animals; Behavior, Animal; Brain Chemistry; Diazepam; Female; Muscimol; Pregnancy; Rats; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A | 1980 |
Involvement of central GABA receptors in the regulation of the urinary bladder function of anaesthetized rats.
Topics: Animals; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Glycine; Levodopa; Male; Muscimol; Muscle Contraction; Rats; Receptors, Cell Surface; Urinary Bladder | 1980 |
Increased benzodiazepine receptor number elicited in vitro by a novel purine, EMD 28422.
Topics: Adenosine; Animals; Binding Sites; Brain; Diazepam; In Vitro Techniques; Male; Muscimol; Purines; Radioligand Assay; Rats; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Tritium | 1980 |
Ethyl beta-carboline-3-carboxylate antagonises the effect of diazepam on a functional GABA receptor.
Topics: Animals; Carbolines; Corpus Striatum; Diazepam; Glutamates; Indoles; Muscimol; Receptors, Cell Surface; Receptors, GABA-A | 1980 |
Kainic acid-induced lesion of rat retina: differential effect on cyclic GMP and benzodiazepine and GABA receptors.
Topics: Animals; Carrier Proteins; Cyclic GMP; Diazepam; gamma-Aminobutyric Acid; Glutamate Dehydrogenase; Intracellular Signaling Peptides and Proteins; Kainic Acid; Male; Muscimol; Pyrrolidines; Rats; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Retina | 1981 |
The insensitivity of developing benzodiazepine receptors to chronic treatment with diazepam, GABA and muscimol in brain cell cultures.
Topics: Animals; Brain; Cell Membrane; Cells, Cultured; Diazepam; Female; Fetus; gamma-Aminobutyric Acid; Kinetics; Mice; Mice, Inbred C57BL; Muscimol; Oxazoles; Pregnancy; Receptors, Drug; Receptors, GABA-A; Receptors, Neurotransmitter | 1981 |
Evidence that ethanol and pentobarbital enhance [3H]diazepam binding at the benzodiazepine-GABA receptor-ionophore complex indirectly.
Topics: Animals; Diazepam; Ethanol; Muscimol; Pentobarbital; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Tritium | 1981 |
Characterization of benzodiazepine and gamma-aminobutyric recognition sites and their endogenous modulators.
Topics: Animals; Benzodiazepines; Binding, Competitive; Carrier Proteins; Cell Membrane; Cerebral Cortex; Diazepam; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Kinetics; Male; Membrane Proteins; Membrane Transport Proteins; Molecular Weight; Muscimol; Nerve Tissue Proteins; Organic Anion Transporters; Phospholipids; Rats; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Solubility; Synaptic Membranes | 1981 |
Histidine modification with diethyl pyrocarbonate shows heterogeneity of benzodiazepine receptors.
Topics: Animals; Benzodiazepines; Brain; Chemical Phenomena; Chemistry; Diazepam; Diethyl Pyrocarbonate; Formates; Histidine; Male; Muscimol; Pentobarbital; Rats; Receptors, Drug; Receptors, GABA-A; Receptors, Neurotransmitter | 1981 |
Rapid effect of enucleation on neurotransmitter receptor binding in chick optic tecta.
Topics: Animals; Cell Membrane; Chickens; Diazepam; Dihydroalprenolol; Glycine; Kinetics; Muscimol; Ocular Physiological Phenomena; Quinuclidinyl Benzilate; Receptors, Neurotransmitter; Serotonin; Superior Colliculi | 1981 |
Studies on the relationship of gamma-aminobutyric acid-stimulated diazepam binding and the gamma-aminobutyric acid receptor.
Topics: Animals; Brain; Cerebellum; Diazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Octoxynol; Polyethylene Glycols; Rats; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Sulfhydryl Reagents | 1981 |
Methyl mercury enhances [3H]diazepam binding in different areas of the rat brain.
Topics: Animals; Brain; Diazepam; gamma-Aminobutyric Acid; Male; Methylmercury Compounds; Muscimol; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, GABA-A; Retina; Spiperone | 1981 |
GABA reduces binding of 3H-methyl beta-carboline-3-carboxylate to brain benzodiazepine receptors.
Topics: Animals; Bicuculline; Brain; Carbolines; Cerebellum; Cerebral Cortex; Diazepam; gamma-Aminobutyric Acid; Indoles; Muscimol; Rats; Receptors, Drug; Receptors, GABA-A; Structure-Activity Relationship | 1981 |
gamma-Aminobutyric acid- and benzodiazepine-binding sites in human anterior pituitary tissue.
Topics: Adult; Aged; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Humans; Isonicotinic Acids; Isoxazoles; Middle Aged; Muscimol; Pituitary Gland, Anterior; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A | 1982 |
Some properties of solubilized GABA receptor.
Topics: Animals; Brain Chemistry; Chromatography, Gel; Diazepam; gamma-Aminobutyric Acid; Kinetics; Male; Methods; Molecular Weight; Muscimol; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, GABA-A; Receptors, Neurotransmitter | 1982 |
Actions of GABAergic agents on dopamine metabolism in the nigrostriatal pathway of the rat.
Topics: 4-Aminobutyrate Transaminase; Aminooxyacetic Acid; Animals; Corpus Striatum; Diazepam; Dopamine; GABA Antagonists; gamma-Aminobutyric Acid; Isoxazoles; Male; Muscimol; Neural Pathways; Pyrones; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Substantia Nigra | 1982 |
Effects of agents which enhance GABA-mediated neurotransmission on licking conflict in rats and exploration in mice.
Topics: Animals; Conflict, Psychological; Diazepam; Exploratory Behavior; Flunitrazepam; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Nitrazepam; Rats; Rats, Inbred Strains; Synaptic Transmission; Urethane; Valproic Acid | 1982 |
Gabaergic regulation of nigrostriatal neurons: coupling of benzodiazepine and GABA receptors.
Topics: Animals; Corpus Striatum; Diazepam; Dopamine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Muscimol; Neural Inhibition; Neural Pathways; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Substantia Nigra | 1982 |
Influence of phospholipase treatments on ligand bindings to a benzodiazepine receptor-GABA receptor-chloride ionophore complex.
Topics: Animals; Cerebellum; Chlorides; Diazepam; In Vitro Techniques; Ionophores; Muscimol; Phospholipases; Phospholipases A; Phospholipases A2; Rats; Receptors, Cell Surface; Receptors, GABA-A; Synaptic Membranes; Type C Phospholipases | 1983 |
Properties of two benzodiazepine binding sites in spinal cord.
Topics: Animals; Benzodiazepines; Binding Sites; Brain; Clonazepam; Diazepam; Glycine; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Spinal Cord; Strychnine | 1983 |
Group-selective reagent modification of the benzodiazepine-gamma-aminobutyric acid receptor-ionophore complex reveals that low-affinity gamma-aminobutyric acid receptors stimulate benzodiazepine binding.
Topics: Animals; Benzodiazepines; Cell Membrane; Cerebellum; Cerebral Cortex; Diazepam; Diazonium Compounds; Diethyl Pyrocarbonate; Flunitrazepam; Hippocampus; Male; Muscimol; Pentobarbital; Rats; Receptors, Cell Surface; Receptors, GABA-A; Sulfanilic Acids | 1983 |
Diazepam increases GABA mediated inhibition in the olfactory cortex slice.
Topics: Animals; Central Nervous System; Cerebral Cortex; Diazepam; Evoked Potentials; gamma-Aminobutyric Acid; Guinea Pigs; Intracellular Membranes; Membrane Potentials; Muscimol; Neural Inhibition; Olfactory Pathways; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Increase of cyclic GMP in cerebellum by methyl-6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate (DMCM).
Topics: Animals; Benzodiazepinones; Carbolines; Cerebellar Cortex; Cyclic GMP; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Indoles; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Stimulation, Chemical | 1983 |
Characterization of a peripheral-type benzodiazepine binding site on human circulating lymphocytes.
Topics: Adult; Benzodiazepinones; Diazepam; Humans; Lymphocytes; Muscimol; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Postnatal development of the benzodiazepine and GABA receptors in the rat spinal cord.
Topics: Animals; Diazepam; Female; In Vitro Techniques; Kinetics; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Spinal Cord; Synaptic Membranes | 1983 |
Diazepam stimulates the binding of GABA and muscimol but not THIP to rat brain membranes.
Topics: Analgesics; Animals; Brain; Diazepam; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Isoxazoles; Kinetics; Male; Muscimol; Oxazoles; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
The effects of kindling on GABA-mediated inhibition in the dentate gyrus of the rat. I. Paired-pulse depression.
Topics: Amygdala; Animals; Diazepam; gamma-Aminobutyric Acid; Hippocampus; Kindling, Neurologic; Male; Membrane Potentials; Muscimol; Neural Inhibition; Neural Pathways; Rats; Synaptic Transmission; Valproic Acid | 1983 |
The benzodiazepine agonist diazepam inhibits basal and secretagogue-stimulated prolactin release in vitro.
Topics: Animals; Benzodiazepinones; Calcimycin; Cells, Cultured; Cyclic AMP; Diazepam; Drug Interactions; Female; Flumazenil; In Vitro Techniques; Male; Muscimol; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains; Thyrotropin | 1984 |
Inhibition of benzodiazepine and GABA receptor binding by amino-gamma-carbolines and other amino acid pyrolysate mutagens.
Topics: Animals; Binding, Competitive; Carbolines; Chlorides; Diazepam; Flunitrazepam; Harmine; Indoles; Ion Channels; Kinetics; Male; Mice; Mice, Inbred Strains; Muscimol; Mutagens; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Seizures | 1984 |
Increase in the Bmax of gamma-aminobutyric acid-A recognition sites in brain regions of mice receiving diazepam.
Topics: Animals; Brain; Cerebellum; Diazepam; gamma-Aminobutyric Acid; Isoniazid; Kinetics; Mice; Motor Activity; Muscimol; Organ Specificity; Rats; Receptors, Cell Surface; Receptors, GABA-A; Seizures | 1984 |
Effects of valproic acid on spinal reflexes and [3H]muscimol and [3H]diazepam binding in brain membranes in rats.
Topics: Animals; Brain; Diazepam; Male; Membranes; Muscimol; Oxazoles; Rats; Rats, Inbred Strains; Reflex; Spinal Cord; Valproic Acid | 1983 |
Diazepam antagonizes GABA- and muscimol-induced changes of acetylcholine release in slices of guinea-pig cerebral cortex.
Topics: Acetylcholine; Animals; Benzodiazepinones; Cerebral Cortex; Diazepam; Flumazenil; GABA Antagonists; Guinea Pigs; In Vitro Techniques; Muscimol; Oxazoles | 1983 |
The bicuculline-like properties of dopamine sulfate in rat brain.
Topics: Animals; Bicuculline; Brain; Diazepam; Dopamine; Drug Interactions; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rats, Inbred Strains; Seizures; Strychnine; Synaptic Membranes | 1984 |
Diazepam potentiates GABA-, but not adenosine-mediated, inhibition of neurons of the nigral pars reticulata.
Topics: Adenosine; Adenosine Monophosphate; Animals; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Evoked Potentials; gamma-Aminobutyric Acid; Glycine; Male; Muscimol; Neural Inhibition; Neural Pathways; Neurons; Rats; Rats, Inbred Strains; Substantia Nigra | 1983 |
Visual evoked potentials in a rabbit model of hepatic encephalopathy. I. Sequential changes and comparisons with drug-induced comas.
Topics: Animals; Diazepam; Disease Models, Animal; Electrodes; Electroencephalography; Evoked Potentials, Visual; Galactosamine; Hepatic Encephalopathy; Muscimol; Pentobarbital; Rabbits | 1984 |
The effect of diazepam and of agents which change GABAergic functions in immobility in mice.
Topics: Aminooxyacetic Acid; Animals; Chlorpromazine; Diazepam; gamma-Aminobutyric Acid; Male; Mice; Motor Activity; Muscimol | 1984 |
Growth hormone secretion of the neonatal rat pituitaries is stimulated by gamma-aminobutyric acid in vitro.
Topics: Aging; Animals; Animals, Newborn; Baclofen; Bicuculline; Diazepam; Female; GABA Antagonists; gamma-Aminobutyric Acid; Growth Hormone; In Vitro Techniques; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Strychnine | 1984 |
A new method for the evaluation of benzodiazepines based on their ability to block muscimol-induced myoclonic jerks in mice.
Topics: Animals; Benzodiazepines; Diazepam; Drug Evaluation; Flunitrazepam; Male; Mice; Muscimol; Myoclonus; Oxazoles; Spinal Cord | 1981 |
Purinergic regulation of food intake.
Topics: Animals; Appetite; Deoxyguanosine; Diazepam; Eating; Food Deprivation; Inosine; Insulin; Male; Muscimol; Purines; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1982 |
Therapeutics of monomethylhydrazine intoxication.
Topics: Animals; Diazepam; Dose-Response Relationship, Drug; Drug Therapy, Combination; Male; Methylhydrazines; Mice; Mice, Inbred ICR; Monomethylhydrazine; Muscimol; Oxazoles; Pyridoxine; Seizures | 1982 |
Anticonflict effect of the benzodiazepines mediated by a GABAergic mechanism in the amygdala.
Topics: Amygdala; Animals; Behavior, Animal; Benzodiazepines; Diazepam; Midazolam; Muscimol; Rats | 1982 |
In vivo modulations by GABA-related drugs of met-enkephalin release in basal ganglia of the cat brain.
Topics: Animals; Bicuculline; Cats; Caudate Nucleus; Diazepam; Drug Interactions; Enkephalin, Methionine; Female; gamma-Aminobutyric Acid; Globus Pallidus; Male; Muscimol; Picrotoxin | 1982 |
Effects of muscimol alone and in combination with diazepam on shuttle-box performance in rats.
Topics: Animals; Avoidance Learning; Bicuculline; Diazepam; Drug Interactions; Male; Muscimol; Oxazoles; Rats; Rats, Inbred Strains | 1981 |
Etomidate stereospecifically stimulates forebrain, but not cerebellar, 3H-diazepam binding.
Topics: Animals; Brain; Cerebellum; Diazepam; Etomidate; Female; gamma-Aminobutyric Acid; Imidazoles; Isoxazoles; Muscimol; Rats; Rats, Inbred Strains; Stereoisomerism; Synaptic Membranes | 1981 |
Decrease in effects of muscimol on the dorsal root after repeated administration of diazepam in rats.
Topics: Animals; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Male; Membrane Potentials; Muscimol; Oxazoles; Rats; Rats, Inbred Strains; Spinal Nerve Roots; Time Factors | 1981 |
Interaction between phencyclidine (PCP) and GABA-ergic drugs: clinical implications.
Topics: Aminooxyacetic Acid; Anesthesia; Animals; Baclofen; Dextroamphetamine; Diazepam; Drug Interactions; gamma-Aminobutyric Acid; Isoxazoles; Male; Mice; Motor Activity; Muscimol; Pain; Phencyclidine; Reflex | 1980 |
Benzodiazepines modulate striatal enkephalin levels via a GABAergic mechanism.
Topics: Aminooxyacetic Acid; Animals; Bicuculline; Corpus Striatum; Diazepam; Endorphins; Enkephalin, Methionine; Enkephalins; Fentanyl; gamma-Aminobutyric Acid; Hypothalamus; Male; Muscimol; Radioimmunoassay; Rats | 1980 |
Neuroleptic-induced prolactin rise: influence of pharmacological alterations of different neurotransmitter system.
Topics: Animals; Apomorphine; Diazepam; Diphenhydramine; Haloperidol; Kinetics; Male; Metergoline; Muscimol; Oxazoles; Piperazines; Prolactin; Rats | 1980 |
Effects of diazepam on GABA-evoked depolarization in rat dorsal root ganglia in vivo.
Topics: Animals; Diazepam; Drug Interactions; gamma-Aminobutyric Acid; Ganglia, Spinal; Male; Membrane Potentials; Muscimol; Rats; Time Factors | 1980 |
Evidence for a tonic GABAergic control of serotonin neurons in the median raphe nucleus.
Topics: Animals; Bicuculline; Brain Stem; Diazepam; gamma-Aminobutyric Acid; Male; Muscimol; Neurons; Picrotoxin; Probenecid; Raphe Nuclei; Rats; Serotonin | 1981 |
Role of GABAergic systems in the development of morphine tolerance in formalin-treated mice.
Topics: Analgesics, Opioid; Animals; Baclofen; Bicuculline; Diazepam; Drug Tolerance; Flumazenil; Formaldehyde; GABA Agonists; GABA Antagonists; Male; Mice; Mice, Inbred Strains; Morphine; Muscimol; Pain; Pain Measurement; Receptors, GABA | 1995 |
Involvement of benzodiazepine/GABA-A receptor complex in ethanol-induced state-dependent learning in rats.
Topics: Animals; Avoidance Learning; Azides; Benzodiazepines; Bicuculline; Diazepam; Ethanol; Evaluation Studies as Topic; Flumazenil; Male; Muscimol; Picrotoxin; Rats; Rats, Wistar; Reaction Time; Receptors, GABA-A | 1995 |
Kavapyrone enriched extract from Piper methysticum as modulator of the GABA binding site in different regions of rat brain.
Topics: Animals; Binding, Competitive; Brain Chemistry; Diazepam; Female; In Vitro Techniques; Muscimol; Ovariectomy; Pentobarbital; Plant Extracts; Plants, Medicinal; Pyrones; Rats; Rats, Sprague-Dawley; Receptors, GABA; Steroids | 1994 |
GABAA/benzodiazepine receptors in acutely isolated hippocampal astrocytes.
Topics: Amino Acid Sequence; Animals; Antibody Specificity; Astrocytes; Bicuculline; Brain; Calcium; Calcium Channels; Carbolines; Cell Separation; Chlorides; Diazepam; Evoked Potentials; gamma-Aminobutyric Acid; Gene Expression; Glial Fibrillary Acidic Protein; Hippocampus; Immunoblotting; In Vitro Techniques; Macromolecular Substances; Membrane Potentials; Molecular Sequence Data; Muscimol; Patch-Clamp Techniques; Peptide Fragments; Picrotoxin; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1995 |
GABAergic and dopaminergic systems may be involved in seizures induced by pyrimethamine in mice.
Topics: Animals; Bicuculline; Diazepam; Dopamine; Drug Interactions; gamma-Aminobutyric Acid; Levodopa; Mice; Mice, Inbred Strains; Muscimol; Phenobarbital; Pyrimethamine; Seizures | 1994 |
[N-methyl-3H]methylphenazepam--a new ligand for benzodiazepine receptors].
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Corpus Striatum; Diazepam; gamma-Aminobutyric Acid; Male; Muscimol; Radioligand Assay; Rats; Receptors, GABA-A; Synaptic Membranes; Tritium | 1993 |
The action of diazepam in the isolated rat detrusor muscle.
Topics: Adenosine Triphosphate; Amino Acids, Diamino; Animals; Atropine; Baclofen; Calcimycin; Calcium; Calcium Channel Blockers; Diazepam; Electric Stimulation; GABA-A Receptor Antagonists; Gallic Acid; Ganglionic Blockers; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Muscimol; Muscle Contraction; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Tetrodotoxin; Urinary Bladder | 1993 |
Enteric GABA-containing nerves projecting to the guinea-pig inferior mesenteric ganglion modulate acetylcholine release.
Topics: Acetylcholine; Animals; Baclofen; Bicuculline; Colon; Diazepam; Electric Stimulation; gamma-Aminobutyric Acid; Ganglia, Sympathetic; Guinea Pigs; In Vitro Techniques; Male; Mesentery; Muscimol; Neural Pathways; Receptors, GABA-A; Receptors, GABA-B; Splanchnic Nerves; Synaptic Transmission | 1993 |
Studies on picrotoxin binding sites of GABAA receptors in rat cortical synaptoneurosomes.
Topics: Animals; Binding Sites; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chlorine; Desoxycorticosterone; Diazepam; In Vitro Techniques; Male; Membranes; Muscimol; Pentobarbital; Picrotoxin; Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Steroids; Synaptosomes | 1994 |
Characterization of the influence of unsaturated free fatty acids on brain GABA/benzodiazepine receptor binding in vitro.
Topics: Animals; Anura; Birds; Brain; Cell Membrane; Cerebral Cortex; Chloride Channels; Diazepam; Fatty Acids, Nonesterified; Fishes; Flunitrazepam; Male; Muscimol; Oleic Acid; Oleic Acids; Phylogeny; Rats; Rats, Wistar; Receptors, GABA; Tritium | 1994 |
Natural mutation of GABAA receptor alpha 6 subunit alters benzodiazepine affinity but not allosteric GABA effects.
Topics: Animals; Azides; Benzodiazepines; Binding Sites; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cerebellum; Cloning, Molecular; Convulsants; Diazepam; gamma-Aminobutyric Acid; Granulocytes; Humans; Kidney; Muscimol; Mutation; Picrotoxin; Rats; Receptors, GABA-A; Recombinant Proteins; Transfection | 1993 |
Cimetidine-induced seizures in mice. Antagonism by some GABAergic agents.
Topics: Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Cimetidine; Diazepam; Female; Mice; Muscimol; Phenobarbital; Phenytoin; Picrotoxin; Receptors, GABA; Seizures; Strychnine | 1993 |
Effects of GABAergic drugs on ethanol-induced gastric lesions.
Topics: Animals; Baclofen; Bicuculline; Diazepam; Ethanol; GABA Antagonists; gamma-Aminobutyric Acid; Gastrointestinal Hemorrhage; Indomethacin; Male; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, GABA; Valproic Acid | 1993 |
Low neurotoxicity of LJC 10,627, a novel 1 beta-methyl carbapenem antibiotic: inhibition of gamma-aminobutyric acidA, benzodiazepine, and glycine receptor binding in relation to lack of central nervous system toxicity in rats.
Topics: Animals; Behavior, Animal; Binding, Competitive; Central Nervous System Diseases; Diazepam; GABA-A Receptor Antagonists; In Vitro Techniques; Male; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, Neurotransmitter; Seizures; Strychnine; Synaptic Membranes; Thienamycins | 1993 |
The spinal GABA system modulates burst frequency and intersegmental coordination in the lamprey: differential effects of GABAA and GABAB receptors.
Topics: Animals; Baclofen; Bicuculline; Culture Techniques; Diazepam; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Lampreys; Locomotion; Motor Neurons; Muscimol; Muscles; N-Methylaspartate; Nerve Net; Neurons; Nipecotic Acids; Proline; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Nerve Roots; Synaptic Transmission | 1993 |
Interaction between benzodiazepine and GABA-A receptors in state-dependent learning.
Topics: Animals; Avoidance Learning; Baclofen; Bicuculline; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Male; Muscimol; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Reference Values | 1993 |
Microdialysis study of the effects of sedative drugs on extracellular histamine in the striatum of freely moving rats.
Topics: Animals; Corpus Striatum; Dialysis; Diazepam; Dronabinol; Extracellular Space; Histamine; Hypnotics and Sedatives; Male; Muscimol; Pentobarbital; Rats; Rats, Wistar; Reserpine | 1993 |
Attenuation of anticonvulsant effects of diazepam after chronic treatment with bicuculline.
Topics: Animals; Anticonvulsants; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Male; Muscimol; Pentobarbital; Rats; Rats, Inbred F344; Rats, Inbred Lew; Receptors, GABA; Sleep | 1993 |
Novel GABA responses from rod-driven retinal horizontal cells.
Topics: Animals; Bicuculline; Chlorides; Crotonates; Diazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Muscimol; Pentobarbital; Perches; Photoreceptor Cells; Receptors, GABA; Retina | 1993 |
Effects of GABAmimetics on electrocorticographic spike discharges induced by guanidinoethanesulfonic acid (amidino-taurine) in the rat.
Topics: Action Potentials; Animals; Cerebral Cortex; Diazepam; Electroencephalography; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rats, Sprague-Dawley; Taurine | 1993 |
Biochemical evaluations of the effects of loreclezole and propofol on the GABAA receptor in rat brain.
Topics: Anesthetics; Animals; Anticonvulsants; Brain; Bridged Bicyclo Compounds, Heterocyclic; Diazepam; Flunitrazepam; GABA Modulators; gamma-Aminobutyric Acid; Hypnotics and Sedatives; In Vitro Techniques; Male; Muscimol; Pentobarbital; Pregnanediones; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sulfur Radioisotopes; Triazoles; Tritium | 1996 |
GABA receptor-mediated inhibition of reflex deglutition in the cat.
Topics: Animals; Bradycardia; Cats; Deglutition; Deglutition Disorders; Diazepam; Female; GABA Antagonists; Male; Muscimol; Receptors, GABA; Reflex | 1996 |
Functional evidence for two native GABAA receptor subtypes in adult rat hippocampus and cerebellum.
Topics: Animals; Cerebellum; Diazepam; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Hippocampus; Male; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1996 |
The neurochemical pathology of thiamine deficiency: GABAA and glutamateNMDA receptor binding sites in a goat model.
Topics: Alcoholism; Amprolium; Animals; Brain Chemistry; Diazepam; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Flunitrazepam; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Goats; In Vitro Techniques; Male; Muscimol; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synaptic Membranes; Synaptosomes; Thiamine Deficiency | 1996 |
Ethanol-induced state-dependent learning is mediated by 5-hydroxytryptamine3 receptors but not by N-methyl-D-aspartate receptor complex.
Topics: Animals; Avoidance Learning; Diazepam; Dizocilpine Maleate; Ethanol; Excitatory Amino Acid Antagonists; Indoles; Muscimol; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Serotonin Antagonists; Tropisetron | 1996 |
Signaling pathway downstream of GABAA receptor in the growth cone.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Axons; Binding Sites; Calcium; Chlorides; Diazepam; Fetus; gamma-Aminobutyric Acid; GTPase-Activating Proteins; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Models, Neurological; Muscimol; Myristoylated Alanine-Rich C Kinase Substrate; Neurites; Picrotoxin; Prosencephalon; Proteins; Rats; Rats, Wistar; Receptors, GABA-A; Signal Transduction; Verapamil | 1996 |
Inhibition of GABAA ligand-gated Cl- channels by zinc in adult rat brain: a regional study.
Topics: Animals; Azides; Benzodiazepines; Brain; Cerebellum; Cerebral Cortex; Chloride Channels; Chlorides; Diazepam; Hippocampus; Ion Channel Gating; Kinetics; Male; Muscimol; Organ Specificity; Radioligand Assay; Rats; Rats, Wistar; Receptors, GABA-A; Synaptosomes; Tritium; Zinc | 1996 |
Receptor binding sites and uptake activities mediating GABA neurotransmission in chronic alcoholics with Wernicke encephalopathy.
Topics: Adult; Aged; Aged, 80 and over; Alcoholism; Binding Sites; Diazepam; Female; Fibrosis; Flunitrazepam; Frontal Lobe; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Motor Cortex; Muscimol; Receptors, GABA; Synaptic Transmission; Wernicke Encephalopathy | 1996 |
GABAA receptors in damaged cerebral cortex areas in human chronic alcoholics.
Topics: Adult; Aged; Alcoholism; Binding Sites; Case-Control Studies; Cerebral Cortex; Diazepam; Flunitrazepam; Humans; In Vitro Techniques; Kinetics; Liver Cirrhosis, Alcoholic; Middle Aged; Muscimol; Receptors, GABA-A; Wernicke Encephalopathy | 1994 |
Ro 15-4513 potentiates, instead of antagonizes, ethanol-induced sleep in mice exposed to small platform stress.
Topics: Animals; Anxiety; Azides; Benzodiazepines; Central Nervous System Depressants; Cerebellum; Chlorides; Diazepam; Drug Synergism; Ethanol; GABA Agonists; GABA Modulators; Male; Mice; Muscimol; Receptors, GABA-A; Sleep; Stress, Psychological | 1996 |
GABAergic influences on plus-maze behaviour in mice.
Topics: Animals; Baclofen; Behavior, Animal; Bicuculline; Diazepam; GABA Modulators; Male; Mice; Mice, Inbred DBA; Muscimol; Nipecotic Acids; Oximes; Picrotoxin; Valproic Acid | 1996 |
Excitatory and trophic action of GABA and related substances in newborn mice and organotypic cerebellar culture.
Topics: Aging; Animals; Animals, Newborn; Bicuculline; Calcium; Cell Count; Cerebellum; Diazepam; GABA Agents; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Intracellular Membranes; Mice; Mice, Inbred ICR; Motor Activity; Muscimol; Organ Culture Techniques; Purkinje Cells | 1997 |
Ultrasonic vocalizations in rat pups: modulation at the gamma-aminobutyric acidA receptor complex and the neurosteroid recognition site.
Topics: Alprazolam; Animals; Diazepam; Female; Male; Muscimol; Pentobarbital; Pregnanolone; Rats; Receptors, GABA-A; Vocalization, Animal | 1997 |
GABA(A) receptors containing the alpha4-subunit: prevalence, distribution, pharmacology, and subunit architecture in situ.
Topics: Animals; Azides; Benzodiazepines; Benzodiazepinones; Brain; Cell Membrane; Cerebellum; Diazepam; Flumazenil; Immunohistochemistry; Immunosorbent Techniques; Macromolecular Substances; Male; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Recombinant Proteins | 1997 |
Acute effects of various GABA receptor agonists and glutamate antagonists on focal hippocampal seizures in freely moving rats elicited by low-frequency stimulation.
Topics: Animals; Anticonvulsants; Ataxia; Carbamazepine; Diazepam; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; GABA Agonists; Hippocampus; Kynurenic Acid; Male; Muscimol; Pipecolic Acids; Quinoxalines; Rats; Rats, Wistar; Seizures | 1998 |
Molecular and functional adaptation of the GABA(A) receptor complex during pregnancy and after delivery in the rat brain.
Topics: Allosteric Regulation; Alternative Splicing; Animals; Brain Chemistry; Cerebral Cortex; Chlorides; Diazepam; Female; Hippocampus; Isotopes; Muscimol; Postpartum Period; Pregnancy; Pregnancy, Animal; Pregnanolone; Protein Isoforms; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; RNA, Messenger | 1998 |
Potentiation of muscimol-induced long-term depression by benzodiazepines and prevention or reversal by pregnenolone sulfate.
Topics: Amnesia; Animals; Barbiturates; Benzodiazepines; Cognition Disorders; Depression; Diazepam; Drug Synergism; Hippocampus; In Vitro Techniques; Male; Muscimol; Pentobarbital; Pregnanolone; Pregnenolone; Rats; Rats, Wistar; Time Factors | 1998 |
Fluorescence imaging of GABAA receptor-mediated intracellular [Cl-] in P19-N cells reveals unique pharmacological properties.
Topics: Animals; Central Nervous System Depressants; Chlorides; Diazepam; DNA Primers; Ethanol; Flunitrazepam; Fluorescent Dyes; GABA Agonists; GABA Modulators; Gene Expression; Mice; Muscimol; Neoplastic Stem Cells; Neuroglia; Pentobarbital; Pregnanolone; Quinolinium Compounds; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tritium | 1999 |
Effects of gamma-aminobutyric acid and peripheral benzodiazepine ligands on duodenal bicarbonate secretion.
Topics: Analysis of Variance; Animals; Antineoplastic Agents; Benzodiazepines; Bicarbonates; Bicuculline; Diazepam; Duodenum; Female; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Intestinal Mucosa; Isoquinolines; Ligands; Male; Muscimol; Rats; Rats, Inbred Lew | 1999 |
GABA(A) receptors on calbindin-immunoreactive myenteric neurons of guinea pig intestine.
Topics: Animals; Calbindins; Cells, Cultured; Diazepam; Dose-Response Relationship, Drug; GABA Agonists; GABA Modulators; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Guinea Pigs; Immunohistochemistry; Intestine, Small; Membrane Potentials; Muscimol; Myenteric Plexus; Neurons; Pentobarbital; Receptors, GABA-A; S100 Calcium Binding Protein G | 2000 |
Participation of GABAergic and histaminergic systems in inhibiting amygdaloid kindled seizures.
Topics: Amygdala; Animals; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Histamine; Imidazoles; Kindling, Neurologic; Male; Muscimol; Rats; Rats, Wistar; Seizures; Thiourea; Valproic Acid | 2000 |
Food intake after diazepam, morphine or muscimol: microinjections In the nucleus accumbens shell.
Topics: Animals; Anti-Anxiety Agents; Diazepam; Eating; Female; GABA Agonists; Injections, Intraventricular; Male; Microinjections; Midazolam; Morphine; Muscimol; Narcotics; Nucleus Accumbens; Rats; Rats, Sprague-Dawley | 2000 |
Effects of buspirone, diazepam, and zolpidem on open field behavior, and brain [3H]muscimol binding after buspirone pretreatment.
Topics: Animals; Autoradiography; Binding Sites; Brain; Buspirone; Diazepam; GABA Agonists; GABA Modulators; Male; Motor Activity; Muscimol; Psychomotor Performance; Pyridines; Rats; Rats, Wistar; Serotonin Receptor Agonists; Tritium; Zolpidem | 2000 |
Benzodiazepine-sensitive GABA(A) receptors limit the activity of the NMDA/NO/cyclic GMP pathway: a microdialysis study in the cerebellum of freely moving rats.
Topics: Animals; Anti-Anxiety Agents; Bicuculline; Cerebellum; Cyclic GMP; Diazepam; Flumazenil; Infusions, Parenteral; Kinetics; Male; Microdialysis; Muscimol; N-Methylaspartate; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Zolpidem | 2000 |
Trimethylolpropane phosphate induces epileptiform discharges in the CA1 region of the rat hippocampus.
Topics: Action Potentials; Animals; Baclofen; Bridged Bicyclo Compounds, Heterocyclic; Convulsants; Diazepam; Electric Impedance; Epilepsy; GABA-A Receptor Agonists; GABA-B Receptor Agonists; Hippocampus; Male; Membrane Potentials; Muscimol; Neurons; Rats; Rats, Sprague-Dawley | 2001 |
The gamma(2)-MSH peptide mediates a central analgesic effect via a GABA-ergic mechanism that is independent from activation of melanocortin receptors.
Topics: alpha-MSH; Analgesics; Animals; Bicuculline; Catalepsy; Central Nervous System Depressants; Diazepam; Drug Interactions; Ethanol; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; gamma-MSH; Male; Mice; Mice, Inbred BALB C; Muscimol; Naloxone; Narcotic Antagonists; Nociceptors; Pain Threshold; Peptides, Cyclic; Receptors, Corticotropin; Receptors, Melanocortin; Tail | 2001 |
Activation of GABA(A) receptors in subthalamic neurons in vitro: properties of native receptors and inhibition mechanisms.
Topics: Animals; Bicarbonates; Bicuculline; Chlorides; Diazepam; Electrophysiology; Flunitrazepam; GABA Agonists; GABA Antagonists; GABA Modulators; Membrane Potentials; Muscimol; Neural Inhibition; Neurons; Organ Culture Techniques; Pentobarbital; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Sesterterpenes; Subthalamic Nucleus | 2001 |
GABA(A) receptor alpha-1 subunit deletion alters receptor subtype assembly, pharmacological and behavioral responses to benzodiazepines and zolpidem.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Benzodiazepines; Chlorides; Diazepam; Exploratory Behavior; Female; Flunitrazepam; GABA Agonists; GABA Modulators; Gene Deletion; Hypnotics and Sedatives; Male; Mice; Mice, Knockout; Motor Activity; Muscimol; Postural Balance; Pyridines; Radioligand Assay; Receptors, GABA-A; Seizures; Zolpidem | 2002 |
Potentiation of muscimol-induced long-term depression by benzodiazepines but not zolpidem.
Topics: Animals; Benzodiazepines; Chlordiazepoxide; Cognition; Diazepam; Drug Synergism; Electric Stimulation; Electrophysiology; GABA Agonists; Hippocampus; Hypnotics and Sedatives; Male; Membrane Potentials; Muscimol; Neuronal Plasticity; Pyramidal Cells; Pyridines; Rats; Rats, Wistar; Zolpidem | 2002 |
On high- and low-affinity agonist sites in GABAA receptors.
Topics: Animals; Bicuculline; Binding Sites; Binding, Competitive; Cells, Cultured; Diazepam; GABA Agonists; GABA Antagonists; GABA Modulators; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Humans; Kidney; Ligands; Muscimol; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Radioligand Assay; Rats; Receptors, GABA-A; Structure-Activity Relationship; Transfection; Xenopus | 2003 |
Auditory responses in multiple sensorimotor song system nuclei are co-modulated by behavioral state.
Topics: Acoustic Stimulation; Animals; Arousal; Auditory Pathways; Behavior, Animal; Bicuculline; Brain; Conscious Sedation; Diazepam; Electrodes, Implanted; Evoked Potentials, Auditory; Excitatory Postsynaptic Potentials; Functional Laterality; GABA Agonists; GABA Antagonists; Hypnotics and Sedatives; Male; Muscimol; Songbirds; Vocalization, Animal; Wakefulness | 2004 |
Reversal of caffeine-induced anxiety by neurosteroid 3-alpha-hydroxy-5-alpha-pregnane-20-one in rats.
Topics: Adrenalectomy; Analysis of Variance; Anesthetics; Animals; Anxiety; Bicuculline; Caffeine; Central Nervous System Stimulants; Corticotropin-Releasing Hormone; Diazepam; Dihydrotestosterone; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; GABA Agonists; GABA Antagonists; Hormone Antagonists; Injections, Intraventricular; Male; Maze Learning; Muscimol; Peptide Fragments; Pregnanolone; Progestins; Rats; Rats, Sprague-Dawley; Reaction Time | 2005 |
GABA(A) receptors mediate orexin-A induced stimulation of food intake.
Topics: Animals; Diazepam; Dose-Response Relationship, Drug; Eating; Flumazenil; GABA Agonists; GABA Antagonists; GABA Modulators; GABA-A Receptor Antagonists; Hyperphagia; Injections, Intraventricular; Intracellular Signaling Peptides and Proteins; Male; Muscimol; Neuropeptides; Orexin Receptors; Orexins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, GABA-A; Receptors, Neuropeptide; Stimulation, Chemical | 2006 |
Anticonvulsant effects of GABA(A) modulators microinfused into area tempestas or substantia nigra in rats exposed to soman.
Topics: Animals; Anticonvulsants; Cerebral Cortex; Chemical Warfare Agents; Diazepam; Drug Therapy, Combination; Ethanol; GABA Agonists; Infusion Pumps; Male; Microinjections; Muscimol; Propofol; Rats; Rats, Wistar; Seizures; Soman; Substantia Nigra | 2006 |
Allosteric uncoupling and up-regulation of benzodiazepine and GABA recognition sites following chronic diazepam treatment of HEK 293 cells stably transfected with alpha1beta2gamma2S subunits of GABA (A) receptors.
Topics: Allosteric Regulation; Animals; Benzodiazepines; Binding Sites; Binding, Competitive; Cell Line; Diazepam; Flumazenil; Flunitrazepam; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Muscimol; Picrotoxin; Protein Subunits; Pyridazines; Radioligand Assay; Rats; Receptors, GABA-A; Receptors, GABA-B; Transfection; Up-Regulation | 2007 |
Treatment with haloperidol and diazepam alters GABA(A) receptor density in the rat brain.
Topics: Animals; Antipsychotic Agents; Autoradiography; Benzodiazepines; Binding Sites; Brain; Diazepam; Disease Models, Animal; Drug Combinations; Flumazenil; Haloperidol; Hippocampus; Humans; Injections, Intraperitoneal; Muscimol; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Schizophrenia; Thalamus; Tissue Distribution | 2008 |
Differential effects of diazepam treatment and withdrawal on recombinant GABAA receptor expression and functional coupling.
Topics: Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Cell Count; Cell Proliferation; Cell Survival; Cells, Cultured; Diazepam; Flunitrazepam; GABA Agonists; GABA Modulators; Gene Expression; Humans; Muscimol; Protein Binding; Protein Biosynthesis; Receptors, GABA-A; Transcriptional Activation | 2008 |
Differential pharmacological properties of GABAA receptors in axon terminals and soma of dentate gyrus granule cells.
Topics: Algorithms; Animals; Data Interpretation, Statistical; Dentate Gyrus; Diazepam; Electrophysiology; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Modulators; Mossy Fibers, Hippocampal; Muscimol; Neurons; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, GABA-A; Zinc | 2009 |
Co-operative effect between gamma-aminobutyric acid A receptors and central-type benzodiazepine receptors on amylase release in rat parotid acinar cells.
Topics: Amylases; Animals; Bicuculline; Clonazepam; Diazepam; Isoproterenol; Male; Muscimol; Parotid Gland; Rats; Rats, Wistar; Receptors, GABA-A | 2010 |
GABAergic regulation of auditory sensory gating in low- and high-anxiety rats submitted to a fear conditioning procedure.
Topics: Acoustic Stimulation; Animals; Anxiety; Behavior, Animal; Benzodiazepines; Bicuculline; Clonixin; Conditioning, Classical; Diazepam; Disease Models, Animal; Electroencephalography; Evoked Potentials, Auditory; Fear; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Inferior Colliculi; Male; Maze Learning; Microinjections; Muscimol; Neurons; Prostaglandin Antagonists; Rats; Rats, Wistar; Sensory Gating; Statistics as Topic | 2010 |
Synergic effect of diazepam and muscimol via presynaptic GABA(A) receptors on glutamatergic evoked EPSCs.
Topics: Animals; Bicuculline; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Excitatory Postsynaptic Potentials; GABA Modulators; GABA-A Receptor Agonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Ion Channels; Muscimol; Neural Inhibition; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, GABA-A | 2011 |
Comparison of cell expression formats for the characterization of GABA(A) channels using a microfluidic patch clamp system.
Topics: Benzodiazepines; Bicuculline; Diazepam; GABA Agents; GABA Agonists; GABA Antagonists; GABA Modulators; Gene Expression; HEK293 Cells; High-Throughput Screening Assays; Humans; Imidazoles; Ion Channel Gating; Microfluidic Analytical Techniques; Muscimol; Patch-Clamp Techniques; Picrotoxin; Receptors, GABA-A; Recombinant Proteins; Transfection | 2012 |
Disrupted Cl(-) homeostasis contributes to reductions in the inhibitory efficacy of diazepam during hyperexcited states.
Topics: Animals; Cells, Cultured; Chlorides; Diazepam; Furosemide; GABA Modulators; Glutamic Acid; Homeostasis; K Cl- Cotransporters; Muscimol; Neural Inhibition; Propofol; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Sodium Potassium Chloride Symporter Inhibitors; Symporters | 2013 |
Expression of the γ2-subunit distinguishes synaptic and extrasynaptic GABA(A) receptors in NG2 cells of the hippocampus.
Topics: Animals; Benzodiazepines; Bicuculline; Diazepam; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Muscimol; Neuroglia; Neurons; Patch-Clamp Techniques; Pentobarbital; Protein Subunits; Receptors, GABA-A; Synapses | 2013 |
GABAAergic stimulation modulates intracellular protein arginine methylation.
Topics: Animals; Arginine; Bicuculline; Cell Differentiation; Cell Line; Diazepam; Drug Synergism; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Intracellular Space; Methylation; Mice, Knockout; Muscimol; Neurons; Protein-Arginine N-Methyltransferases; Receptors, GABA-A; Signal Transduction | 2014 |
Benzodiazepine-dependent stabilization of GABA(A) receptors at synapses.
Topics: Animals; Carrier Proteins; Cells, Cultured; Diazepam; GABA Agonists; GABA Antagonists; GABA Modulators; Membrane Proteins; Mice; Muscimol; Protein Binding; Protein Subunits; Protein Transport; Pyridazines; Receptors, GABA-A; Synapses; Synaptic Potentials | 2014 |
Bidirectional Control of Social Behavior by Activity within Basolateral and Central Amygdala of Primates.
Topics: Animals; Basolateral Nuclear Complex; Bicuculline; Central Amygdaloid Nucleus; Diazepam; Dose-Response Relationship, Drug; Female; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Macaca nemestrina; Magnetic Resonance Imaging; Male; Microinjections; Muscimol; Neural Inhibition; Social Behavior; Statistics, Nonparametric | 2016 |
Peripheral GABAA receptor signaling contributes to visceral hypersensitivity in a mouse model of colitis.
Topics: Animals; Bicuculline; Colitis; Colon; Dextran Sulfate; Diazepam; Disease Models, Animal; Inflammatory Bowel Diseases; Mice; Mice, Inbred C57BL; Muscimol; Pain; Receptors, GABA-A | 2022 |