muscimol has been researched along with chlorine in 223 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 81 (36.32) | 18.7374 |
| 1990's | 98 (43.95) | 18.2507 |
| 2000's | 32 (14.35) | 29.6817 |
| 2010's | 11 (4.93) | 24.3611 |
| 2020's | 1 (0.45) | 2.80 |
| Authors | Studies |
|---|---|
| Hara, N; Ichinose, M; Sawada, M | 1 |
| Ehrmann, ML; Mileson, BE; Schwartz, RD | 1 |
| Edgar, PP; Schwartz, RD | 1 |
| Ho, IK; Yu, S | 1 |
| Arce, C; Bugeda, J; Castro, E; Gonzalez, MP; Oset-Gasque, MJ; Parramon, M | 1 |
| Schwartz, RD; Yu, X | 2 |
| Kuriyama, K; Ueha, T | 2 |
| Allan, AM; Baier, LD | 1 |
| Banerjee, PK; Depaulis, A; Hechler, V; Snead, OC; Vergnes, M | 1 |
| Kaila, K; Pasternack, M; Rydqvist, B; Voipio, J | 1 |
| Aibara, K; Akaike, N; Itabashi, S; Sasaki, H | 1 |
| Chesley, S; Galpern, WR; Greenblatt, DJ; Lumpkin, M; Miller, LG; Schatzki, A; Shader, RI | 1 |
| Browning, MD; Endo, S; Harris, RA; Leidenheimer, NJ; Machu, TK; Olsen, RW | 1 |
| Galpern, WR; Greenblatt, DJ; Lumpkin, M; Miller, LG; Shader, RI | 1 |
| Buck, KJ; Harris, RA; McQuilkin, SJ | 1 |
| Frye, GD; Mathew, J | 1 |
| Davies, M; Wood, JD | 1 |
| Harris, RA; Leidenheimer, NJ | 1 |
| Maisky, A; Rebrov, I; Tennila, T; Yukhananov, R | 1 |
| Bowman, JW; Lee, BL; Thompson, DP; Whaley, HA | 1 |
| Chesley, S; Greenblatt, DJ; Lopez, F; Miller, LG; Schatzki, A; Shader, RI | 1 |
| Dohi, T; Kitayama, S; Morita, K; Tsujimoto, A | 1 |
| Allen, TG; Burnstock, G | 1 |
| Chesley, S; Greenblatt, DJ; Lopez, F; Miller, LG; Schatzki, A; Shader, RI; Thompson, ML | 1 |
| Hablitz, JJ; Mistry, DK | 1 |
| Blasquez, C; Bunel, DT; Delbende, C; Jégou, S; Vaudry, H | 1 |
| Akaike, N; Ikemoto, Y; Kits, KS; Oyama, Y | 1 |
| de Costa, BR; Lewin, AH; Moody, EJ; Rice, KC; Skolnick, P | 1 |
| Niles, L | 1 |
| Dinarello, CA; Dunlap, K; Galpern, WR; Miller, LG; Turner, TJ | 1 |
| Hajós, F; Kardos, J; Kovács, I; Simon-Trompler, E | 1 |
| Biggio, G; Concas, A; Sanna, E; Santoro, G; Serra, M | 1 |
| Korpi, ER; Oja, SS; Saransaari, P | 1 |
| Fincher, AS; Frye, GD; Griffith, WH; Lorenzetti, M; Trzeciakowski, J | 1 |
| Catt, KJ; Stojilković, SS; Virmani, MA | 1 |
| Kuriyama, K; Taguchi, J | 1 |
| Blinn, JR; Morrow, AL; Paul, SM; Purdy, RH | 1 |
| Dodd, PR; Gundlach, AL; Harper, PA; Johnston, GA; Lummis, SC | 1 |
| Greenblatt, DJ; Heller, J; Lumpkin, M; Miller, LG; Shader, RI; Weill, CL | 1 |
| Blakeman, DP; Davis, JP; Im, WB | 1 |
| Barnard, EA; Devine, J; Macdonald, RL; Moss, SJ; Nayeem, N; Porter, NM; Smart, TG; Stephenson, FA | 1 |
| Browning, MD; Dunwiddie, TV; Hahner, LD; Harris, RA; Leidenheimer, NJ | 1 |
| Braestrup, C; Honore, T; Nielsen, M | 1 |
| Alho, H; Costa, E; Ferrero, P; Guidotti, A; Santi, MR; Vicini, S | 1 |
| Paul, SM; Schwartz, RD; Skolnick, P; Suzdak, PD | 1 |
| Cañadas, S; Giménez, A; González, MP; Sánchez, C | 1 |
| Paul, SM; Schwartz, RD; Suzdak, PD | 1 |
| Majewska, MD; Paul, SM; Schwartz, RD | 1 |
| Labarca, R; Paul, SM; Schwartz, RD; Skolnick, P; Wess, MJ | 1 |
| Allan, AM; Harris, RA | 6 |
| Cole, RJ; Eldefrawi, AT; Eldefrawi, ME; Gant, DB; Valdes, JJ | 1 |
| Majewska, MD | 1 |
| Allan, AM; Bleck, V; Harris, RA; Huidobro-Toro, JP | 1 |
| Inenaga, K; Mason, WT | 1 |
| Greenblatt, DJ; Miller, LG; Roy, RB; Shader, RI; Summer, WR | 1 |
| Allan, AM; Gallaher, EJ; Gionet, SE; Harris, RA | 1 |
| Moody, EJ; Paul, SM; Skolnick, P; Suzdak, PD | 1 |
| Schneider, HH; Stephens, DN; Weidmann, R; Zimmermann, L | 1 |
| Akaike, N; Ikemoto, Y; Kijima, H | 1 |
| Barry, D; Clemmesen, L; Hemmingsen, R; Ulrichsen, J | 1 |
| Heuschneider, G; Schwartz, RD | 1 |
| Bleck, V; Harris, RA; Lewin, E; Peris, J; Zahniser, NR | 2 |
| Fukuda, H; Matsumoto, K; Ono, H; Yamazaki, J | 1 |
| Allan, AM; Harris, RA; Spuhler, KP | 1 |
| Mindlin, MC; Schwartz, RD | 1 |
| Greenblatt, DJ; Kaplan, GB; Lopez, F; Miller, LG; Shader, RI | 1 |
| Aosaki, T; Kanai, Y; Manabe, S; Wada, O | 1 |
| Biggio, G; Cau, A; Corda, MG; Laudani, U; Longoni, B; Paci, S; Salvadori, S | 1 |
| Olsen, RW; Ransom, RW; Turner, DM; Yang, JS | 1 |
| Paul, SM; Schwartz, RD; Seale, TW; Skolnick, P | 1 |
| Agey, MW; Dunn, SM; Shelman, RA | 1 |
| Erdö, SL; Wolff, JR | 1 |
| Crawley, JN; Deutsch, SI; Drugan, RC; Morrow, AL; Paul, SM; Weizman, A; Weizman, R | 1 |
| Kardos, J | 1 |
| Korpi, ER; Uusi-Oukari, M | 2 |
| Lopez, F; Miller, LG; Roy, RB; Weill, CL | 1 |
| Miller, LG; Roy, RB; Weill, CL | 1 |
| Greenblatt, DJ; Lopez, F; Miller, LG; Roy, RB; Shader, RI; Woolverton, S | 1 |
| Cash, DJ; Subbarao, K | 1 |
| McCormick, DA | 1 |
| Kastin, AJ; Miller, LG; Roy, RB | 1 |
| Akaike, N; Hattori, K; Inomata, N; Oomura, Y | 1 |
| Allan, AM; Buck, KJ; Harris, RA | 1 |
| Amatsu, M; Okada, Y; Yamauchi, R | 1 |
| Nistri, A; Sivilotti, L | 1 |
| Crofton, KM; Reiter, LW | 1 |
| Morrow, AL; Paul, SM; Suzdak, PD | 1 |
| Hetmar, O; Nielsen, M | 1 |
| Karanian, JW; Morrow, AL; Paul, SM; Suzdak, PD | 1 |
| Gorman, CM; Kettenmann, H; Pritchett, DB; Schofield, PR; Seeburg, PH; Sontheimer, H | 1 |
| Abalis, IM; Eldefrawi, AT; Eldefrawi, ME | 1 |
| Kempner, ES; Paul, SM; Schwartz, RD; Skolnick, P; Thomas, JW | 1 |
| Haefely, W; Möhler, H; Richards, JG; Schoch, P | 1 |
| Majewska, MD; Schwartz, RD | 1 |
| Barker, JL; Harrington, JW; Harrison, NL; Majewska, MD | 1 |
| Olsen, RW; Yang, JS | 1 |
| Morrow, AL; Paul, SM | 1 |
| Biggio, G; Concas, A; Mele, S | 1 |
| Albert, J; Lingle, CJ; Marder, E; O'Neil, MB | 1 |
| Kaneko, A; Tachibana, M | 1 |
| Dunlap, K | 1 |
| Braunwalder, A; Cheney, DL; Loo, P; Wood, PL; Yokoyama, N | 1 |
| Jackson, MB | 1 |
| Braunwalder, A; Cheney, DL; Loo, P; Wood, PL | 1 |
| Karobath, M; Supavilai, P | 1 |
| Guidotti, A | 1 |
| Axelrod, J; Gallager, DW; Hirata, F; Mallorga, P; Strittmatter, W; Tallman, JF; Thomas, JW | 1 |
| Olsen, RW; Stephenson, FA | 2 |
| Olsen, RW; Snowman, AM | 1 |
| Fujimoto, M; Okabayashi, T | 1 |
| Fukuda, H; Matsumoto, K | 1 |
| Barker, JL; Segal, M | 1 |
| Kato, R; Muraki, T; Yamazoe, Y | 1 |
| Douglas, WW; Taraskevich, PS; Tomiko, SA | 1 |
| Aloisi, F; Gallo, V; Levi, G | 1 |
| Proctor, WR; Soldo, BL; Staley, KJ | 1 |
| Koff, JM; Miller, LG | 1 |
| Demontis, GC; Longoni, B; Olsen, RW | 1 |
| Burnham, WM; Lôscher, W; Nobrega, JN; Richter, A | 1 |
| Angelides, KJ; Duffy, S; Fraser, DD; Kettenmann, H; MacVicar, BA; Perez-Velazquez, JL | 1 |
| De Rijk, TC; Ghijsen, WE; Kamphuis, W; Lopes da Silva, FH; Titulaer, MN | 1 |
| Fukuda, H; Ito, Y; Segawa, K | 1 |
| Biggio, G; Concas, A; Cuccheddu, T; Maciocco, E; Santoro, G; Serra, M | 1 |
| Allan, AM; Harris, RA; McQuilkin, SJ; Mihic, SJ; Whatley, VJ | 1 |
| Samochocki, M; Strosznajder, J | 2 |
| Hu, XJ; Ticku, MK | 1 |
| Martin, D; Schwartz, RD; Wagner, JP; Yu, X | 1 |
| Lukasiewicz, PD; Maple, BR; Werblin, FS | 1 |
| Dunn, SM; Thuynsma, RP | 1 |
| Jackson, MB; Zhang, SJ | 1 |
| Liu, CC; Snead, OC | 1 |
| Brown, GB; Brown, P; DeLorey, TM; Kissin, I | 1 |
| Dowling, JE; Qian, H | 1 |
| Blednov, Y; Simpson, VJ | 1 |
| Gordey, M; Kang, M; Olsen, RW; Spigelman, I | 1 |
| Brozowski, SJ; Hadingham, KL; Harris, RA; Whatley, VJ; Whiting, PJ | 1 |
| Brunner, H; Jarolimek, W; Lewen, A; Misgeld, U | 1 |
| Kang, M; Olsen, RW; Sapp, DW; Spigelman, I | 1 |
| Fukura, H; Igarashi, M; Komiya, Y | 1 |
| Fukuda, H; Ito, Y; Kobayashi, M; Segawa, K | 1 |
| Kivastik, T; Liljequist, S; Pokk, P; Sobol, D; Zharkovsky, A | 1 |
| Liljequist, S; Pokk, P; Zharkovsky, A | 1 |
| Miyata, H; Nagayama, T; Takahata, M | 1 |
| Kettenmann, H; Labrakakis, C; Müller, T; Schmidt, K | 1 |
| Ghijsen, WE; Titulaer, MN | 1 |
| Chang, X; Javors, MA; King, TS; Levinson, C; Ticku, MK | 1 |
| Akwa, Y; Baulieu, EE; El-Etr, M; Robel, P | 1 |
| Barker, JL; Li, YX; Schaffner, AE; Walton, MK | 1 |
| Biggio, G; Concas, A; Floris, S; Follesa, P; Mostallino, MC; Tuligi, G | 1 |
| Barbaccia, ML; Biggio, G; Concas, A; Follesa, P; Grisenti, P; Mostallino, MC; Porcu, P; Purdy, RH; Trabucchi, M | 1 |
| Ballanyi, K; Brockhaus, J | 1 |
| Kaila, K; Lahtinen, H; Lamsa, K; Payne, JA; Pirvola, U; Rivera, C; Ruusuvuori, E; Saarma, M; Voipio, J | 1 |
| de Jeu, MT; Dudek, FE; Gribkoff, VK; Park, WK; Pennartz, CM; Pieschl, RL; Strecker, GJ; Wisialowski, TA | 1 |
| González, MP; Herrero, MT; López, E; Oset-Gasque, MJ; Vicente, S | 1 |
| Chistina Grobin, A; Devaud, LL; Inglefield, JR; Morrow, AL; Schwartz-Bloom, RD | 1 |
| Bekar, LK; Jabs, R; Walz, W | 1 |
| Bekar, LK; Walz, W | 2 |
| Akaike, N; Lükensmejer, B; Nabekura, J; Nielsen, M; Poulsen, CF; Westh-Hansen, SE; Witt, MR | 1 |
| Banerjee, PK; Olsen, RW; Snead, OC | 1 |
| Sah, R; Schwartz-Bloom, RD | 1 |
| Bence, M; Everest, H; Forrest-Owen, W; Lightman, SL; McArdle, CA; Williams, B | 1 |
| Inglefield, JR; Shafer, TJ | 1 |
| Ritter, B; Zhang, W | 1 |
| Baufreton, J; Bioulac, B; Dovero, S; Dufy, B; Garret, M; Taupignon, A | 1 |
| Akaike, N; Jang, IS; Jeong, HJ | 1 |
| Chase, MH; Morales, FR; Xi, MC | 1 |
| Akemann, W; Diez-Garcia, J; Grandes, P; Ho, CS; Itohara, S; Iwasato, T; Joho, RH; Knöpfel, T; Matsushita, S; Metzger, F; Repunte-Canonigo, V | 1 |
| Akaike, N; Fukuda, A; Furuta, A; Iwaki, T; Nabekura, J; Okabe, A; Shimizu-Okabe, C; Ueno, T | 1 |
| Homanics, GE; Korpi, ER; Kralic, JE; Morrow, AL; O'Buckley, TK | 1 |
| Hodge, CW; Homanics, GE; Khisti, RT; Kralic, JE; Morrow, AL; O'Buckley, TK | 1 |
| DeFazio, RA; Heger, S; Moenter, SM; Ojeda, SR | 1 |
| Bauer, J; Flemmer, A; Forbush, B; Kintner, DB; Schomberg, SL; Su, G; Sun, D | 1 |
| Ferguson, C; Grobin, AC; Homanics, GE; Kralic, JE; Morrow, AL; O'Buckley, TK; Renzi, K; Wheeler, M | 1 |
| Abrosimov, IY; Andreev, AA; Belykh, NP; Kalinina, MS; Karpova, MN; Kuzina, OS; Rebrov, IG | 1 |
| Khisti, RT; Kumar, S; Morrow, AL | 1 |
| Mazzone, SB; McGovern, AE | 1 |
| Heinrich, M; Milenković, I; Reinert, T; Rübsamen, R; Turecek, R; Witte, M | 1 |
| Aptel, H; Boukhaddaoui, H; Hilaire, C; Mallié, S; Pieraut, S; Scamps, F; Valmier, J | 1 |
| Eun, JS; Han, H; Hong, JT; Kim, HC; Ma, Y; Oh, KW | 1 |
| Hwang, JC; Lee, MC; Lin, JT; Tung, LC | 1 |
| Han, H; Hong, JT; Kim, YB; Ma, Y; Nam, SY; Oh, KW; Yun, YP | 1 |
| Delpire, E; Mathews, GC; Polley, N; Zhu, L | 1 |
| Andreev, AA; Kalinina, MV; Karpova, MN; Klishina, NY; Kusnetzova, LV; Rebrov, IG | 2 |
| Brodwick, M; Ishibashi, H; Kitamura, A; Nabekura, J; Takatsuru, Y; Watanabe, M | 1 |
| French, AS; Höger, U; Panek, I; Pfeiffer, K; Torkkeli, PH | 1 |
| Hirao, K; Ishibashi, H; Nabekura, J; Yamaguchi, J | 1 |
| Baulieu, EE; Ghoumari, AM; Levenes, C; Rakotomamonjy, J; Schumacher, M | 1 |
| Han, JY; Hong, JT; Moon, DC; Oh, KW; Park, KS | 1 |
| Akerman, CJ; Ilie, A; Raimondo, JV | 1 |
| Asiedu, MN; Kaila, K; Malan, TP; Mejia, G; Ossipov, MK; Price, TJ | 1 |
| Cebada, J; Cortes, C; Flores, A; Galicia, S; Galindo, F | 1 |
| Davies, PA; Deeb, TZ; Frost, GD; Moss, SJ; Nakamura, Y | 1 |
| Han, JY; Hong, JT; Lee, CI; Oh, KW | 1 |
| Cheng, P; Taylor-Burds, C; Wray, S | 1 |
| Dudek, M; Hyytiä, P | 1 |
| Biscocho, D; Cook, JG; Leise, EM; Long, J; Shah, N | 1 |
| Aikins, AO; Cunningham, JT; Farmer, GE; Little, JT | 1 |
| Asami, S; Doi, M; Fukuda, H; Ito, Y; Koshiba, T; Murakoshi, Y | 1 |
| Hahner, L; Harris, RA; McQuilkin, S | 1 |
| Brozowski, SJ; Harris, RA; Machu, TK; McKernan, RM; McManaman, JL; Olsen, RW; Smith, GB; Valenzuela, CF; VanRenterghem, BB; Whiting, P | 1 |
| Ho, IK; Ito, Y | 1 |
| Braun, D; Chmielewski, PA; Kane, JM; Miller, JA | 1 |
| Akahane, K; Fukuda, H; Ito, Y; Kimura, Y; Miyasaka, T | 1 |
| Cleton, A; Danhof, M; Ghijsen, W; Van der Graaf, PH; Voskuyl, R | 1 |
| Cooper, RL; Meacham, CA; Shafer, TJ; Ward, TR | 1 |
| Cleton, A; Danhof, M; Ghijsen, W; Odman, J; Van der Graaf, PH; Voskuyl, R | 1 |
| Grobin, AC; Matthews, DB; Montoya, D; Morrow, AL; Swartzwelder, HS; Wilson, WA | 1 |
| Grobin, AC; Morrow, AL | 1 |
| Eun, JS; Hong, JT; Kim, YB; Lee, MK; Ma, H; Ma, Y; Nam, SY; Oh, KW | 1 |
| Dietz, B; Milenkovic, I; Nerlich, J; Reinert, T; Rübsamen, R; Witte, M | 1 |
2 review(s) available for muscimol and chlorine
| Article | Year |
|---|---|
Benzodiazepine receptors resolved.
Topics: Animals; Antibodies, Monoclonal; Autoradiography; Benzodiazepines; Benzodiazepinones; Bicuculline; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Chlorides; Clonazepam; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Histocytochemistry; Humans; Immunologic Techniques; Ionophores; Muscimol; Neurons; Radioisotopes; Radioligand Assay; Receptors, GABA-A; Spinal Cord; Synapses; Tissue Distribution | 1986 |
Biochemical pharmacology of the GABA receptor-ionophore protein complex.
Topics: Animals; Brain; Chlorides; Flunitrazepam; Humans; Ion Channels; Ionophores; Kinetics; Muscimol; Nerve Tissue Proteins; Picrotoxin; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter; Sesterterpenes | 1983 |
221 other study(ies) available for muscimol and chlorine
| Article | Year |
|---|---|
Interleukin-2 inhibits the GABA-induced Cl- current in identified Aplysia neurons.
Topics: Animals; Aplysia; Bicuculline; Chlorides; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia; In Vitro Techniques; Interleukin-2; Ion Channels; Membranes; Muscimol; Neurons; Picrotoxin; Recombinant Proteins; Seawater | 1992 |
Alterations in the gamma-aminobutyric acid-gated chloride channel following transient forebrain ischemia in the gerbil.
Topics: Animals; Autoradiography; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Chlorides; gamma-Aminobutyric Acid; Gerbillinae; Ion Channel Gating; Ischemic Attack, Transient; Male; Membrane Proteins; Motor Activity; Muscimol | 1992 |
Functionally relevant gamma-aminobutyric acidA receptors: equivalence between receptor affinity (Kd) and potency (EC50)?
Topics: Animals; Binding Sites; Cerebral Cortex; Chloride Channels; Chlorides; Ethylmaleimide; gamma-Aminobutyric Acid; Ion Channel Gating; Kinetics; Male; Membrane Proteins; Muscimol; Neurons; Radioisotopes; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes; Tritium | 1992 |
Effects of acute pentobarbital administration on GABAA receptor-regulated chloride uptake in rat brain synaptoneurosomes.
Topics: Animals; Brain; Cerebellum; Cerebral Cortex; Chlorides; Flunitrazepam; Male; Muscimol; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes | 1992 |
Mechanism through which GABAA receptor modulates catecholamine secretion from bovine chromaffin cells.
Topics: Animals; Calcium; Catecholamines; Cattle; Chlorides; Cytosol; Enterochromaffin Cells; Fluorescence; In Vitro Techniques; Membrane Potentials; Muscimol; Nicotine; Quinolinium Compounds; Receptors, GABA-A | 1992 |
Inhibition of GABA-gated chloride channel function by arachidonic acid.
Topics: Animals; Arachidonic Acid; Cerebral Cortex; Chloride Channels; Chlorides; Fatty Acids; gamma-Aminobutyric Acid; Indomethacin; Ion Channel Gating; Male; Membrane Proteins; Muscimol; Phospholipases A; Phospholipases A2; Rats; Rats, Inbred Strains; Synaptosomes | 1992 |
Functional alterations in cerebral GABAA receptor complex associated with formation of alcohol dependence: analysis using GABA-dependent 36Cl- influx into neuronal membrane vesicles.
Topics: Administration, Inhalation; Alcohol Withdrawal Delirium; Alcoholism; Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Flunitrazepam; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred Strains; Muscimol; Neurons; Radioligand Assay; Receptors, GABA-A; Synaptic Membranes; Synaptic Vesicles | 1992 |
Effect of thiol group modification on ion flux and ligand binding properties of the GABAA-benzodiazepine receptor chloride channel complex.
Topics: Animals; Chlorides; Chlorine; Diazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Male; Mice; Mice, Inbred ICR; Muscimol; Radioisotopes; Receptors, GABA-A; Sulfhydryl Compounds; Sulfhydryl Reagents | 1992 |
The GABAA receptor complex in experimental absence seizures in rat: an autoradiographic study.
Topics: Animals; Autoradiography; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Chlorides; Convulsants; Epilepsy, Absence; Flunitrazepam; GABA-A Receptor Antagonists; Ion Channels; Ionophores; Male; Membrane Proteins; Muscimol; Organ Specificity; Pyramidal Tracts; Pyridazines; Rats; Rats, Wistar; Receptors, GABA-A; Sulfur Radioisotopes; Tritium | 1992 |
Inward current caused by sodium-dependent uptake of GABA in the crayfish stretch receptor neurone.
Topics: Animals; Astacoidea; Chlorides; gamma-Aminobutyric Acid; Ion Channel Gating; Mechanoreceptors; Membrane Potentials; Muscimol; Neurons; Sodium | 1992 |
gamma-Aminobutyric acid-induced response in rat dissociated paratracheal ganglion cells.
Topics: Animals; Chlorides; Diazepam; Drug Synergism; Electric Conductivity; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia; Muscimol; Pentobarbital; Rats; Rats, Inbred Strains; Trachea | 1992 |
Prenatal exposure to benzodiazepine--I. Prenatal exposure to lorazepam in mice alters open-field activity and GABAA receptor function.
Topics: Animals; Brain; Cerebral Cortex; Chlorides; Female; Gestational Age; Lorazepam; Maternal-Fetal Exchange; Mice; Motor Activity; Muscimol; Pregnancy; Receptors, GABA-A; Reference Values | 1991 |
Cyclic AMP-dependent protein kinase decreases gamma-aminobutyric acidA receptor-mediated 36Cl- uptake by brain microsacs.
Topics: Animals; Biological Transport; Brain; Cell Membrane; Cerebellum; Cerebral Cortex; Chlorides; Hippocampus; Kinetics; Macromolecular Substances; Mice; Mice, Inbred ICR; Muscimol; Protein Kinases; Receptors, GABA-A | 1991 |
Ethanol-induced alterations in the function of cerebral GABAA receptor complex: effect on GABA-dependent 36Cl- influx into cerebral membrane vesicles.
Topics: Animals; Brain; Chloride Channels; Chlorides; Culture Techniques; Dose-Response Relationship, Drug; Ethanol; Flunitrazepam; Isoquinolines; Membrane Proteins; Mice; Muscimol; Radioligand Assay; Receptors, GABA-A; Synaptic Membranes; Synaptic Vesicles | 1991 |
Chronic benzodiazepine administration. VII. Behavioral tolerance and withdrawal and receptor alterations associated with clonazepam administration.
Topics: Animals; Behavior, Animal; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chlorides; Clonazepam; Convulsants; Drug Tolerance; Flumazenil; Male; Mice; Motor Activity; Muscimol; Receptors, GABA-A; Substance Withdrawal Syndrome | 1991 |
Modulation of gamma-aminobutyric acidA receptor-operated chloride channels by benzodiazepine inverse agonists is related to genetic differences in ethanol withdrawal seizure severity.
Topics: Animals; Benzodiazepines; Carbolines; Chloride Channels; Chlorides; Convulsants; Ethanol; Flunitrazepam; Genetic Predisposition to Disease; Male; Membrane Proteins; Mice; Mice, Inbred Strains; Muscimol; Receptors, GABA-A; Seizures; Substance Withdrawal Syndrome | 1991 |
EDTA and EGTA stimulate 36Cl- uptake into rat brain synaptoneurosomes.
Topics: Animals; Biological Transport; Brain; Calcium; Chelating Agents; Chloride Channels; Chlorides; Chlorine; Edetic Acid; Egtazic Acid; Male; Membrane Proteins; Muscimol; Radioisotopes; Rats; Rats, Inbred Strains; Synaptosomes | 1991 |
Regulation of the GABAA receptor/ion channel complex by intracellular GABA levels.
Topics: Aminocaproates; Animals; Cerebral Cortex; Chloride Channels; Chlorides; Cyclohexanecarboxylic Acids; gamma-Aminobutyric Acid; Hydrazines; Isoniazid; Male; Membrane Proteins; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes; Vigabatrin | 1991 |
A transient osmotic permeabilization method for the introduction of impermeant molecules into functional brain membrane vesicles.
Topics: Alkaline Phosphatase; Animals; Capsules; Carbon Radioisotopes; Cell Membrane; Cell Membrane Permeability; Chloride Channels; Chlorides; Chlorine; Concanavalin A; Flunitrazepam; Hypotonic Solutions; Membrane Proteins; Mice; Mice, Inbred ICR; Muscimol; Pyridazines; Radioisotope Dilution Technique; Radioisotopes; Receptors, Concanavalin A; Receptors, GABA-A; Sucrose; Tritium | 1991 |
Effect of ethanol and DSIP on the 36Cl-flux in synaptosomal vesicles.
Topics: Animals; Biological Transport; Cerebral Cortex; Chlorides; Delta Sleep-Inducing Peptide; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Membrane Lipids; Muscimol; Rats; Receptors, GABA-A; Synaptosomes; Temperature | 1991 |
Effects of dihydroavermectin B1a and analogs on stretcher muscle of the lined shore crab, Pachygrapsus crassipes.
Topics: Animals; Anthelmintics; Bicuculline; Brachyura; Caenorhabditis; Chlorides; Cobalt; Dose-Response Relationship, Drug; Drug Interactions; gamma-Aminobutyric Acid; In Vitro Techniques; Ivermectin; Membrane Potentials; Membranes; Motor Endplate; Muscimol; Muscles; Picrotoxin; Sesterterpenes; Structure-Activity Relationship; Synapses; Time Factors | 1991 |
Chronic administration of benzodiazepines--V. Rapid onset of behavioral and neurochemical alterations after discontinuation of alprazolam.
Topics: Alprazolam; Animals; Behavior, Animal; Brain Chemistry; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chlorides; Down-Regulation; Drug Tolerance; Ion Channels; Male; Mice; Motor Activity; Muscimol; Receptors, GABA-A; Substance Withdrawal Syndrome; Sulfur Radioisotopes | 1990 |
GABAergic modulation of catecholamine release from cultured bovine adrenal chromaffin cells. Evidence for the involvement of Cl(-)-dependent Ca2+ entry.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Adrenal Glands; Animals; Calcium; Calcium Radioisotopes; Catecholamines; Cattle; Cells, Cultured; Chlorides; Chromaffin System; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Ion Channels; Muscimol; Pentobarbital; Time Factors; Veratridine | 1990 |
GABAA receptor-mediated increase in membrane chloride conductance in rat paratracheal neurones.
Topics: Animals; Bicuculline; Cell Membrane; Chlorides; Electrophysiology; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Membrane Potentials; Muscimol; Neurons; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Tetrodotoxin; Trachea | 1990 |
Chronic morphine administration augments benzodiazepine binding and GABAA receptor function.
Topics: Animals; Brain Chemistry; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Chlorine; Flunitrazepam; In Vitro Techniques; Ion Channels; Male; Mice; Morphine; Muscimol; Naltrexone; Radioisotopes; Receptors, GABA-A; Sulfur Radioisotopes | 1990 |
Activation of subconductance states by gamma-aminobutyric acid and its analogs in chick cerebral neurons.
Topics: Analgesics; Animals; Cells, Cultured; Cerebral Cortex; Chick Embryo; Chlorides; Electric Conductivity; gamma-Aminobutyric Acid; Ion Channel Gating; Ion Channels; Isonicotinic Acids; Isoxazoles; Muscimol; Neurons | 1990 |
Effects of ions and ionic channel activators or blockers on release of alpha-MSH from perifused rat hypothalamic slices.
Topics: 4-Aminopyridine; alpha-MSH; Animals; Bicuculline; Calcium; Chlorides; Hypothalamus; Ion Channel Gating; Ion Channels; Male; Membrane Potentials; Muscimol; Ouabain; Potassium; Rats; Rats, Inbred Strains; Secretory Rate; Sodium; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Veratridine | 1990 |
GABA affects the glutamate receptor-chloride channel complex in mechanically isolated and internally perfused Aplysia neurons.
Topics: Animals; Anura; Aplysia; Baclofen; Chlorides; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Muscimol; Neurons; Perfusion; Receptors, Glutamate; Receptors, Neurotransmitter | 1990 |
Site-specific acylation of GABA-gated Cl- channels: effects on 36Cl- uptake.
Topics: Acylation; Animals; Biological Transport, Active; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Chlorides; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Ligands; Male; Membrane Proteins; Muscimol; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes | 1991 |
Melatonin interaction with the benzodiazepine-GABA receptor complex in the CNS.
Topics: Animals; Anti-Anxiety Agents; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cerebral Cortex; Chlorides; Diazepam; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Ion Channels; Melatonin; Muscimol; Prosencephalon; Rats; Receptors, GABA-A; Serotonin; Synaptosomes | 1991 |
Interleukin-1 augments gamma-aminobutyric acidA receptor function in brain.
Topics: Animals; Brain; Chlorides; Interleukin-1; Interleukin-6; Male; Mice; Mice, Inbred Strains; Muscimol; Neurons; Receptors, GABA-A; Substrate Specificity; Synapses; Synaptosomes; Time Factors; Tumor Necrosis Factor-alpha | 1991 |
Enantioselectivity at the physiologically active GABAA receptor.
Topics: Animals; Bicuculline; Binding, Competitive; Cell Membrane; Cerebral Cortex; Chloride Channels; Chlorides; In Vitro Techniques; Membrane Proteins; Muscimol; Oxazolidinones; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stereoisomerism; Structure-Activity Relationship | 1991 |
Neurochemical action of the general anaesthetic propofol on the chloride ion channel coupled with GABAA receptors.
Topics: Anesthetics; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Chlorides; Flunitrazepam; Male; Membrane Proteins; Muscimol; Propofol; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1991 |
Modification of chloride flux across brain membranes by inhibitory amino acids in developing and adult mice.
Topics: Amino Acids; Animals; Animals, Newborn; beta-Alanine; Brain; Chlorides; gamma-Aminobutyric Acid; Membranes; Mice; Mice, Inbred Strains; Muscimol; Osmolar Concentration; Taurine | 1990 |
Comparison of contractile responses of the guinea pig ileum longitudinal muscle to ethanol and GABAA agonists.
Topics: Animals; Atropine; Bicuculline; Chlorides; Ethanol; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Pentobarbital; Picrotoxin; Receptors, GABA-A; Sesterterpenes; Taurine; Tetrodotoxin | 1990 |
Stimulation of luteinizing hormone release by gamma-aminobutyric acid (GABA) agonists: mediation by GABAA-type receptors and activation of chloride and voltage-sensitive calcium channels.
Topics: Amino Acid Sequence; Animals; Baclofen; Calcium Channels; Cells, Cultured; Chloride Channels; Chlorides; Female; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Isoxazoles; Luteinizing Hormone; Membrane Proteins; Molecular Sequence Data; Muscimol; Nifedipine; Pituitary Gland, Anterior; Pyridazines; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1990 |
Functional modulation of cerebral gamma-aminobutyric acidA receptor/benzodiazepine receptor/chloride ion channel complex with ethyl beta-carboline-3-carboxylate: presence of independent binding site for ethyl beta-carboline-3-carboxylate.
Topics: Animals; Baclofen; Binding Sites; Brain; Carbolines; Cells, Cultured; Chloride Channels; Chlorides; Drug Interactions; Flunitrazepam; Male; Membrane Proteins; Mice; Muscimol; Receptors, GABA-A; Tritium | 1990 |
Synthesis, metabolism, and pharmacological activity of 3 alpha-hydroxy steroids which potentiate GABA-receptor-mediated chloride ion uptake in rat cerebral cortical synaptoneurosomes.
Topics: Acetates; Animals; Cerebral Cortex; Chlorides; Desoxycorticosterone; Drug Synergism; Isomerism; Male; Molecular Conformation; Muscimol; Pregnanes; Pregnanolone; Rats; Rats, Inbred Strains; Receptors, GABA-A; Structure-Activity Relationship; Synaptosomes | 1990 |
Increased gamma-aminobutyric acid receptor function in the cerebral cortex of myoclonic calves with an hereditary deficit in glycine/strychnine receptors.
Topics: Animals; Benzodiazepines; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cerebral Cortex; Chloride Channels; Chlorides; Chlorine; Diazepam; Female; gamma-Aminobutyric Acid; Ligands; Male; Membrane Proteins; Muscimol; Myoclonus; Radioisotopes; Receptors, GABA-A; Receptors, Glycine; Receptors, Neurotransmitter; Synaptic Membranes | 1990 |
Augmentation of GABAA receptor function by chronic exposure to GABA-neutral and GABA-negative benzodiazepine ligands in cultured cortical neurons.
Topics: Animals; Appetite Depressants; Binding Sites; Carbolines; Chick Embryo; Chlorides; Culture Techniques; Flumazenil; Muscimol; Neurons; Ouabain; Receptors, GABA-A | 1990 |
Na(+)-dependent GABA transport system scavenges endogenous external GABA and prevents desensitization of GABAA receptors in rat cerebrocortical synaptoneurosomes.
Topics: Animals; Cerebral Cortex; Chlorides; gamma-Aminobutyric Acid; Male; Muscimol; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Proline; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sodium; Synaptosomes | 1990 |
Cloned GABA receptors are maintained in a stable cell line: allosteric and channel properties.
Topics: Animals; Antibodies, Monoclonal; Barbiturates; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cell Line; Chlorides; Clone Cells; Convulsants; DNA; gamma-Aminobutyric Acid; Membrane Potentials; Muscimol; Neurons; Plasmids; Receptors, GABA-A; Spinal Cord; Transfection | 1990 |
Phosphorylation-independent effects of second messenger system modulators on gamma-aminobutyric acidA receptor complex function.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Chlorides; Colforsin; Cyclic AMP; Edetic Acid; Isoquinolines; Mice; Mice, Inbred ICR; Muscimol; Phosphorylation; Piperazines; Protein Kinases; Pyridazines; Receptors, GABA-A; Second Messenger Systems | 1990 |
Radiation inactivation of brain [35S]t-butylbicyclophosphorothionate binding sites reveals complicated molecular arrangements of the GABA/benzodiazepine receptor chloride channel complex.
Topics: Animals; Binding Sites; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Carbolines; Cerebellum; Cerebral Cortex; Chlorides; Etazolate; Etomidate; In Vitro Techniques; Ion Channels; Molecular Weight; Muscimol; Organophosphorus Compounds; Radioligand Assay; Rats; Receptors, GABA-A; Sulfur Radioisotopes | 1985 |
Gamma-aminobutyric acid and chloride channels: regulation by neuropeptides.
Topics: Animals; Carbolines; Cells, Cultured; Cerebellum; Chlorides; gamma-Aminobutyric Acid; Hippocampus; Humans; Ion Channels; Muscimol; Nerve Tissue Proteins; Receptors, GABA-A | 1985 |
Ethanol stimulates gamma-aminobutyric acid receptor-mediated chloride transport in rat brain synaptoneurosomes.
Topics: Animals; Bicuculline; Biological Transport; Brain; Cell-Free System; Chlorides; Ethanol; In Vitro Techniques; Ion Channels; Muscimol; Pentobarbital; Picrotoxin; Rats; Receptors, GABA-A; Synaptosomes | 1986 |
Possible involvement of low and high affinity GABA receptors in the chloride influx into synaptosomes.
Topics: 4-Aminobutyrate Transaminase; Aldehyde Oxidoreductases; Animals; Chlorides; Diazepam; gamma-Aminobutyric Acid; Ion Channels; Muscimol; Phenobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes | 1986 |
gamma-Aminobutyric acid (GABA)- and barbiturate-mediated 36Cl- uptake in rat brain synaptoneurosomes: evidence for rapid desensitization of the GABA receptor-coupled chloride ion channel.
Topics: Animals; Cerebral Cortex; Chlorides; Dose-Response Relationship, Drug; Ethanol; gamma-Aminobutyric Acid; Ion Channels; Male; Muscimol; Pentobarbital; Ranidae; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes | 1986 |
Factors modulating the sensitivity of the GABA receptor-gated chloride ion channel.
Topics: Animals; Chlorides; Ion Channels; Male; Muscimol; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes | 1986 |
Acute stress enhances the activity of the GABA receptor-gated chloride ion channel in brain.
Topics: Adrenalectomy; Animals; Brain; Chlorides; In Vitro Techniques; Ion Channels; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stress, Physiological; Swimming; Synaptosomes | 1987 |
Acute and chronic ethanol treatments alter GABA receptor-operated chloride channels.
Topics: Animals; Cerebellum; Chlorides; Drug Tolerance; Ethanol; Ion Channels; Male; Mice; Mice, Inbred DBA; Muscimol; Receptors, GABA-A | 1987 |
Action of tremorgenic mycotoxins on GABAA receptor.
Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Electric Organ; Flunitrazepam; In Vitro Techniques; Ion Channels; Male; Muscimol; Mycotoxins; Rats; Rats, Inbred Strains; Receptors, GABA-A; Torpedo; Tremor | 1987 |
Antagonist-type interaction of glucocorticoids with the GABA receptor-coupled chloride channel.
Topics: Animals; Bicuculline; Binding Sites; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Chlorides; Frontal Lobe; Glucocorticoids; Ion Channels; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes | 1987 |
Alcohol and the GABA receptor-chloride channel complex of brain.
Topics: Animals; Brain; Chlorides; Ethanol; Ion Channels; Male; Mice; Muscimol; Receptors, GABA-A | 1987 |
Gamma-aminobutyric acid modulates chloride channel activity in cultured primary bovine lactotrophs.
Topics: Animals; Bicuculline; Cattle; Cells, Cultured; Chlorides; gamma-Aminobutyric Acid; Ion Channels; Membrane Potentials; Muscimol; Pituitary Gland, Anterior; Prolactin | 1987 |
Chronic benzodiazepine administration. II. Discontinuation syndrome is associated with upregulation of gamma-aminobutyric acidA receptor complex binding and function.
Topics: Animals; Binding Sites; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chlorides; Drug Tolerance; Flumazenil; Flunitrazepam; Ion Channels; Lorazepam; Male; Mice; Motor Activity; Muscimol; Receptors, GABA-A; Time Factors | 1988 |
Genetic selection for benzodiazepine ataxia produces functional changes in the gamma-aminobutyric acid receptor chloride channel complex.
Topics: Animals; Ataxia; Chlorides; Diazepam; Ethanol; Flunitrazepam; Ion Channels; Isoxazoles; Mice; Muscimol; Phenobarbital; Receptors, GABA-A; Time Factors | 1988 |
Modulation of the benzodiazepine/gamma-aminobutyric acid receptor chloride channel complex by inhalation anesthetics.
Topics: Anesthesia, Inhalation; Anesthetics; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chlorides; Enflurane; Ether; Halothane; Ion Channels; Male; Methoxyflurane; Muscimol; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes | 1988 |
Neurochemistry of brain chloride channels: genetic variation in modulation by GABA agonists, alcohol and benzodiazepines.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Brain; Chlorides; Ethanol; Genetic Variation; Ion Channels; Male; Mice; Muscimol; Receptors, GABA-A; Species Specificity | 1988 |
Decreased sensitivity to benzodiazepine receptor agonists and increased sensitivity to inverse agonists following chronic treatments: evidence for separate mechanisms.
Topics: Animals; Anti-Anxiety Agents; Appetite Depressants; Benzodiazepines; Carbolines; Chlorides; Diazepam; Drug Interactions; Drug Tolerance; Exploratory Behavior; Ion Channels; Kindling, Neurologic; Locomotion; Lorazepam; Mice; Muscimol; Pentylenetetrazole; Rats; Receptors, GABA-A | 1988 |
Kinetic and pharmacological properties of the GABA-induced chloride current in Aplysia neurones: a 'concentration clamp' study.
Topics: Animals; Aplysia; beta-Alanine; Chlorides; Diazepam; gamma-Aminobutyric Acid; Ion Channels; Kinetics; Muscimol; Neurons; Pentobarbital | 1988 |
The GABA/benzodiazepine receptor chloride channel complex during repeated episodes of physical ethanol dependence in the rat.
Topics: Alcoholism; Animals; Chlorides; Diazepam; Ion Channels; Male; Muscimol; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, GABA-A; Substance Withdrawal Syndrome; Sulfur Radioisotopes | 1988 |
cAMP and forskolin decrease gamma-aminobutyric acid-gated chloride flux in rat brain synaptoneurosomes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Brain; Bucladesine; Chloride Channels; Chlorides; Colforsin; Cyclic AMP; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Proteins; Muscimol; Rats; Synaptosomes | 1989 |
Chemical kindling decreases GABA-activated chloride channels of mouse brain.
Topics: Animals; Autoradiography; Brain Chemistry; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Convulsants; gamma-Aminobutyric Acid; Ion Channels; Kindling, Neurologic; Male; Mice; Mice, Inbred ICR; Muscimol; Sulfur Radioisotopes | 1989 |
Macrolide compounds, ivermectin and milbemycin D, stimulate chloride channels sensitive to GABAergic drugs in cultured chick spinal neurons.
Topics: Animals; Anti-Bacterial Agents; Bicuculline; Cells, Cultured; Chick Embryo; Chlorides; Diazepam; gamma-Aminobutyric Acid; Ion Channels; Ivermectin; Lactones; Macrolides; Membrane Potentials; Muscimol; Neurons; Picrotoxin; Sesterterpenes; Spinal Cord | 1989 |
gamma-Aminobutyric acid-activated chloride channels: relationship to genetic differences in ethanol sensitivity.
Topics: Animals; Cerebellum; Chloride Channels; Chlorides; Ethanol; gamma-Aminobutyric Acid; Genetics; Ion Channels; Male; Membrane Proteins; Mice; Muscimol; Rats; Sleep | 1988 |
Inhibition of the GABA receptor-gated chloride ion channel in brain by noncompetitive inhibitors of the nicotinic receptor-gated cation channel.
Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Chloride Channels; Chlorides; In Vitro Techniques; Ion Channels; Male; Membrane Proteins; Muscimol; Parasympatholytics; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Nicotinic; Tubocurarine | 1988 |
Sensitivity to ethanol hypnosis and modulation of chloride channels does not cosegregate with pentobarbital sensitivity in HS mice.
Topics: Animals; Arousal; Brain; Chloride Channels; Chlorides; Dose-Response Relationship, Drug; Drug Tolerance; Ethanol; Flunitrazepam; Ion Channels; Male; Membrane Proteins; Mice; Muscimol; Pentobarbital; Receptors, GABA-A; Sleep Stages | 1989 |
Genetic differences in coupling of benzodiazepine receptors to chloride channels.
Topics: Animals; Cerebral Cortex; Chloride Channels; Chlorides; Ethanol; Flunitrazepam; Ion Channels; Male; Membrane Proteins; Mice; Muscimol; Receptors, GABA-A; Sleep | 1989 |
Diazepam sensitizes mice to FG 7142 and reduces muscimol-stimulated 36Cl- flux.
Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carbolines; Chlorides; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Ion Channels; Kindling, Neurologic; Mice; Mice, Inbred ICR; Muscimol | 1989 |
Interaction of caffeine with the GABAA receptor complex: alterations in receptor function but not ligand binding.
Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Caffeine; Cerebral Cortex; Chlorides; In Vitro Techniques; Ion Channels; Kinetics; Ligands; Male; Mice; Muscimol; Receptors, GABA-A; Sulfur Radioisotopes; Synaptosomes | 1989 |
Suppression of GABA-induced chloride current by 3-amino-1-methyl-5H-pyrido[4,3-b]indole (Trp-P-2).
Topics: Alanine; Animals; Carbolines; Chlorides; Flumazenil; GABA Antagonists; Ganglia, Spinal; Male; Membrane Potentials; Mice; Mice, Inbred Strains; Muscimol; Neurons, Afferent; Taurine | 1989 |
Distribution and pharmacological properties of the GABAA/benzodiazepine/chloride ionophore receptor complex in the brain of the fish Anguilla anguilla.
Topics: Anguilla; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Convulsants; Flunitrazepam; gamma-Aminobutyric Acid; Ionophores; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, GABA-A; Tissue Distribution | 1989 |
Steroid anesthetics and naturally occurring analogs modulate the gamma-aminobutyric acid receptor complex at a site distinct from barbiturates.
Topics: Anesthetics; Animals; Barbiturates; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; In Vitro Techniques; Male; Muscimol; Pregnanediones; Rats; Rats, Inbred Strains; Receptors, GABA-A; Steroids; Structure-Activity Relationship | 1989 |
Differential seizure sensitivities to picrotoxinin in two inbred strains of mice (DBA/2J and BALB/c ByJ): parallel changes in GABA receptor-mediated chloride flux and receptor binding.
Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Dose-Response Relationship, Drug; Frontal Lobe; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Muscimol; Pentobarbital; Picrotoxin; Receptors, GABA-A; Seizures; Species Specificity; Synaptosomes | 1989 |
Fluorescence measurements of anion transport by the GABAA receptor in reconstituted membrane preparations.
Topics: Animals; Anions; Biological Transport; Brain; Cattle; Cell Membrane; Cerebral Cortex; Chlorides; Iodides; Kinetics; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Spectrometry, Fluorescence; Synaptosomes | 1989 |
Age-related loss of t-[35S]butylbicyclophosphorothionate binding to the gamma-aminobutyric acidA receptor-coupled chloride ionophore in rat cerebral cortex.
Topics: Aging; Animals; Binding Sites; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Cerebral Cortex; Chlorides; Female; Ionophores; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sulfur Radioisotopes | 1989 |
Stress-induced behavioral depression in the rat is associated with a decrease in GABA receptor-mediated chloride ion flux and brain benzodiazepine receptor occupancy.
Topics: Animals; Brain; Chlorides; Depression; Flumazenil; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stress, Physiological; Synaptosomes | 1989 |
36Cl- flux measurements on GABAA receptor-activated chloride exchange. Multiple mechanisms of the chloride channel inactivation.
Topics: Animals; Baclofen; Cerebellum; Chloride Channels; Chlorides; Chlorine; Diazepam; In Vitro Techniques; Membrane Proteins; Muscimol; Neurons; Pertussis Toxin; Radioisotopes; Rats; Receptors, GABA-A; Virulence Factors, Bordetella | 1989 |
Cerebellar GABAA receptor binding and function in vitro in two rat lines developed for high and low alcohol sensitivity.
Topics: Alcohol Drinking; Animals; Cerebellum; Chlorides; Ethanol; In Vitro Techniques; Male; Membranes; Motor Activity; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1989 |
Persistent alterations in GABAA receptor binding and function after prenatal lorazepam administration in the chick.
Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chick Embryo; Chickens; Chlorides; Female; Flunitrazepam; Lorazepam; Muscimol; Pregnancy; Prenatal Exposure Delayed Effects; Radioligand Assay; Receptors, GABA-A | 1989 |
Chronic clonazepam administration decreases gamma-aminobutyric acidA receptor function in cultured cortical neurons.
Topics: Animals; Benzodiazepines; Cells, Cultured; Cerebral Cortex; Chick Embryo; Chlorides; Clonazepam; Drug Administration Schedule; Flumazenil; Muscimol; Picrotoxin; Receptors, GABA-A; Sesterterpenes | 1989 |
GABAA receptor-mediated chloride flux in brain homogenates from rat lines with differing innate alcohol sensitivities.
Topics: Animals; Brain; Chlorides; Drug Tolerance; Ethanol; In Vitro Techniques; Male; Muscimol; Rats; Receptors, GABA-A | 1989 |
Chronic benzodiazepine administration. IV. Rapid development of tolerance and receptor downregulation associated with alprazolam administration.
Topics: Alprazolam; Animals; Behavior, Animal; Benzodiazepines; Binding Sites; Brain Chemistry; Cerebellum; Chloride Channels; Chlorides; Down-Regulation; Drug Administration Schedule; Drug Tolerance; Hippocampus; Male; Medulla Oblongata; Membrane Proteins; Mice; Motor Activity; Muscimol; Receptors, GABA-A | 1989 |
Responses of gamma-aminobutyrate receptor from rat brain: similarity of different preparation methods; muscimol induced desensitization and chloride exchange.
Topics: Animals; Cerebral Cortex; Chlorides; Ficoll; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Models, Neurological; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes | 1989 |
GABA as an inhibitory neurotransmitter in human cerebral cortex.
Topics: Baclofen; Cerebral Cortex; Chlorides; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Injections; Intracellular Membranes; Muscimol; Neural Inhibition; Neurons; Neurotransmitter Agents | 1989 |
MIF-1 and Tyr-MIF-1 augment muscimol-stimulated chloride uptake in cerebral cortex.
Topics: Animals; Cerebral Cortex; Chlorides; Male; Mice; MSH Release-Inhibiting Hormone; Muscimol; Receptors, GABA-A | 1989 |
gamma-Aminobutyric-acid- and pentobarbitone-gated chloride currents in internally perfused frog sensory neurones.
Topics: Action Potentials; Amino Acids; Animals; Chlorides; Dose-Response Relationship, Drug; Drug Interactions; gamma-Aminobutyric Acid; Ganglia, Spinal; In Vitro Techniques; Ion Channels; Muscimol; Neurons, Afferent; Pentobarbital | 1985 |
Fluidization of brain membranes by A2C does not produce anesthesia and does not augment muscimol-stimulated 36Cl- influx.
Topics: Anesthesia; Animals; Benzyl Alcohols; Brain Chemistry; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Chlorine; gamma-Aminobutyric Acid; Male; Membrane Fluidity; Membranes; Mice; Mice, Inbred ICR; Muscimol; Radioisotopes; Stearates; Stearic Acids; Synaptosomes; Temperature | 1989 |
Effect of GABA (gamma-aminobutyric acid) on neurotransmission in inferior colliculus slices from the guinea pig.
Topics: Action Potentials; Animals; Baclofen; Bicuculline; Chlorides; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Inferior Colliculi; Muscimol; Neural Inhibition | 1989 |
Pharmacology of a novel effect of gamma-aminobutyric acid on the frog optic tectum in vitro.
Topics: Animals; Bicuculline; Chlorides; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Midazolam; Muscimol; Pentobarbital; Rana temporaria; Superior Colliculi | 1989 |
Pyrethroid insecticides and the gamma-aminobutyric acidA receptor complex: motor activity and the acoustic startle response in the rat.
Topics: Animals; Chlordiazepoxide; Chlorides; Dose-Response Relationship, Drug; Haloperidol; Male; Motor Activity; Muscimol; Nitriles; Picrotoxin; Pyrethrins; Rats; Receptors, GABA-A; Reflex, Startle | 1987 |
Steroid hormone metabolites potentiate GABA receptor-mediated chloride ion flux with nanomolar potency.
Topics: Animals; Brain; Cerebral Cortex; Chlorides; In Vitro Techniques; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Steroids; Synaptosomes | 1987 |
Chronic treatment with lithium chloride: reduced number of GABA receptors in frontal cortex of rat brain.
Topics: Animals; Chlorides; Frontal Lobe; Lithium; Lithium Chloride; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1988 |
Chronic ethanol administration alters gamma-aminobutyric acid, pentobarbital and ethanol-mediated 36Cl- uptake in cerebral cortical synaptoneurosomes.
Topics: Administration, Inhalation; Animals; Cerebral Cortex; Chlorides; Dose-Response Relationship, Drug; Ethanol; gamma-Aminobutyric Acid; Male; Muscimol; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synapses | 1988 |
Transient expression shows ligand gating and allosteric potentiation of GABAA receptor subunits.
Topics: Allosteric Regulation; Blotting, Northern; Cells, Cultured; Chloride Channels; Chlorides; Cloning, Molecular; Electric Conductivity; Humans; Macromolecular Substances; Membrane Proteins; Muscimol; Receptors, GABA-A; Structure-Activity Relationship; Transfection | 1988 |
Actions of avermectin B1a on the gamma-aminobutyric acidA receptor and chloride channels in rat brain.
Topics: Animals; Bicuculline; Binding, Competitive; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Chlorides; Dose-Response Relationship, Drug; Flunitrazepam; Ivermectin; Kinetics; Male; Membrane Proteins; Muscimol; Rats; Receptors, GABA-A | 1986 |
Radiation inactivation studies of the benzodiazepine/gamma-aminobutyric acid/chloride ionophore receptor complex.
Topics: Animals; Barbiturates; Benzodiazepines; Benzodiazepinones; Binding Sites; Brain; Carbolines; Cell Membrane; Chlorides; Diazepam; Flumazenil; Flunitrazepam; Ionophores; Male; Molecular Weight; Muscimol; Picrotoxin; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1985 |
gamma-Aminobutyric acid agonists and antagonists alter chloride flux across brain membranes.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Animals; Baclofen; Bicuculline; Brain; Cell Membrane; Chlorides; gamma-Aminobutyric Acid; In Vitro Techniques; Isonicotinic Acids; Isoxazoles; Liver; Male; Mice; Mice, Inbred DBA; Muscimol; Picrotoxin; Receptors, GABA-A; Sodium; Sulfates; Taurine; Temperature | 1986 |
Pregnenolone-sulfate: an endogenous antagonist of the gamma-aminobutyric acid receptor complex in brain?
Topics: Adrenal Glands; Animals; Binding Sites; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Male; Muscimol; Picrotoxin; Pregnenolone; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stimulation, Chemical | 1987 |
Structure-activity relationships for steroid interaction with the gamma-aminobutyric acidA receptor complex.
Topics: Animals; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Desoxycorticosterone; Electric Conductivity; Ethanol; Evoked Potentials; Flunitrazepam; Muscimol; Pregnanes; Progesterone; Rats; Rats, Inbred Strains; Receptors, GABA-A; Steroids; Structure-Activity Relationship | 1987 |
gamma-Aminobutyric acid receptor-regulated 36Cl- flux in mouse cortical slices.
Topics: Androstanes; Animals; Azasteroids; Barbiturates; Cerebral Cortex; Chlorides; Dose-Response Relationship, Drug; Electrophysiology; Flunitrazepam; Male; Mathematics; Mice; Muscimol; Receptors, GABA-A | 1987 |
Benzodiazepine enhancement of gamma-aminobutyric acid-mediated chloride ion flux in rat brain synaptoneurosomes.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Brain; Carbolines; Chlorides; Clonazepam; Diazepam; Drug Synergism; Flurazepam; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rats, Inbred Strains; Synaptosomes | 1988 |
Foot shock stress decreases chloride efflux from rat brain synaptoneurosomes.
Topics: Animals; Brain; Chlorides; Electroshock; gamma-Aminobutyric Acid; Male; Muscimol; Pentobarbital; Rats; Rats, Inbred Strains; Stress, Psychological; Synaptosomes | 1987 |
A GABA-activated chloride-conductance not blocked by picrotoxin on spiny lobster neuromuscular preparations.
Topics: Action Potentials; Animals; Chlorides; Drug Resistance; gamma-Aminobutyric Acid; In Vitro Techniques; Ivermectin; Lactones; Muscimol; Nephropidae; Neuromuscular Junction; Picrotoxin; Species Specificity | 1986 |
Effects of gamma-aminobutyric acid on isolated cone photoreceptors of the turtle retina.
Topics: Action Potentials; Animals; Bicuculline; Chlorides; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; Muscimol; Photoreceptor Cells; Picrotoxin; Time Factors; Turtles | 1986 |
Gamma-aminobutyric acid and alcohol actions: neurochemical studies of long sleep and short sleep mice.
Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cerebellum; Chlorides; Diencephalon; Drug Synergism; Ethanol; Female; gamma-Aminobutyric Acid; Hippocampus; Mice; Muscimol; Pentobarbital; Sleep; Telencephalon | 1986 |
Functional and pharmacological differences between two types of GABA receptor on embryonic chick sensory neurons.
Topics: Animals; Baclofen; Bicuculline; Calcium; Chick Embryo; Chlorides; Culture Techniques; gamma-Aminobutyric Acid; Ganglia, Spinal; Ion Channels; Membrane Potentials; Muscimol; Neurons; Receptors, Cell Surface; Receptors, GABA-A; Sensory Receptor Cells; Synaptic Transmission | 1984 |
In vitro characterization of benzodiazepine receptor agonists, antagonists, inverse agonists and agonist/antagonists.
Topics: Animals; Brain; Chlorides; Etazolate; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Muscimol; Rats; Receptors, GABA-A | 1984 |
Chemically activated channels in muscle and spinal cord.
Topics: Acetylcholine; Animals; Chlorides; gamma-Aminobutyric Acid; Ion Channels; Kinetics; Membrane Potentials; Muscimol; Neuromuscular Junction; Pentobarbital; Receptors, Cholinergic; Receptors, GABA-A; Spinal Cord; Stimulation, Chemical; Synaptic Transmission | 1984 |
In vitro characterization of agonist, antagonist, inverse agonist and agonist/antagonist benzodiazepines.
Topics: Animals; Benzodiazepines; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Etazolate; Ion Channels; Muscimol; Rats; Receptors, GABA-A | 1984 |
Action of pyrazolopyridines as modulators of [3H]flunitrazepam binding to the gaba/benzodiazepine receptor complex of the cerebellum.
Topics: Animals; Anti-Anxiety Agents; Bicuculline; Binding Sites; Cerebellum; Chlorides; Etazolate; Flunitrazepam; Isoxazoles; Male; Muscimol; Nicotinic Acids; Pyrazoles; Rats; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Tritium | 1981 |
Pharmacological and biochemical evidence for an interaction between the benzodiazepine and GABA receptors.
Topics: Animals; Benzodiazepines; Binding Sites; Brain; Carrier Proteins; Chlorides; gamma-Aminobutyric Acid; Ionophores; Membrane Proteins; Muscimol; Rats; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Receptors, Neurotransmitter; Synaptic Membranes; Synaptic Transmission | 1980 |
Studies on benzodiazepine receptors.
Topics: Animals; Benzodiazepines; Binding Sites; Cerebral Cortex; Chlorides; Diazepam; gamma-Aminobutyric Acid; Ligands; Methyltransferases; Muscimol; Neural Inhibition; Phenytoin; Phospholipids; Rats; Receptors, Drug; Receptors, GABA-A; Receptors, Neurotransmitter | 1980 |
Solubilization by CHAPS detergent of barbiturate-enhanced benzodiazepine-GABA receptor complex.
Topics: Animals; Barbiturates; Cattle; Chlorides; Cholic Acids; Chromatography, Gel; Dose-Response Relationship, Drug; Muscimol; Pentobarbital; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Solubility; Time Factors | 1982 |
Chloride-dependent enhancement by barbiturates of gamma-aminobutyric acid receptor binding.
Topics: Animals; Barbiturates; Benzodiazepines; Brain; Cattle; Chlorides; Muscimol; Pentobarbital; Receptors, Cell Surface; Receptors, GABA-A; Synaptic Membranes | 1982 |
Influence of phospholipase treatments on ligand bindings to a benzodiazepine receptor-GABA receptor-chloride ionophore complex.
Topics: Animals; Cerebellum; Chlorides; Diazepam; In Vitro Techniques; Ionophores; Muscimol; Phospholipases; Phospholipases A; Phospholipases A2; Rats; Receptors, Cell Surface; Receptors, GABA-A; Synaptic Membranes; Type C Phospholipases | 1983 |
Anisatin modulation of temperature-dependent inhibition [3H]muscimol binding by chloride ion.
Topics: Animals; Anions; Brain; Chlorides; Kinetics; Lactones; Male; Muscimol; Oxazoles; Plants, Toxic; Protein Binding; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Sesquiterpenes; Spiro Compounds; Synaptic Membranes; Temperature | 1983 |
Rat hippocampal neurons in culture: properties of GABA-activated Cl- ion conductance.
Topics: Animals; Cells, Cultured; Chlorides; Embryo, Mammalian; gamma-Aminobutyric Acid; Glycine; Hippocampus; Ion Channels; Membrane Potentials; Muscimol; Rats; Stimulation, Chemical | 1984 |
Inhibition of benzodiazepine and GABA receptor binding by amino-gamma-carbolines and other amino acid pyrolysate mutagens.
Topics: Animals; Binding, Competitive; Carbolines; Chlorides; Diazepam; Flunitrazepam; Harmine; Indoles; Ion Channels; Kinetics; Male; Mice; Mice, Inbred Strains; Muscimol; Mutagens; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Seizures | 1984 |
GABA acts directly on cells of pituitary pars intermedia to alter hormone output.
Topics: Chlorides; gamma-Aminobutyric Acid; Melanocyte-Stimulating Hormones; Muscimol; Pituitary Gland; Potassium; Secretory Rate | 1983 |
Muscimol potentiation of acidic amino acid release from cerebellar synaptosomes is chloride dependent.
Topics: Animals; Aspartic Acid; Cerebellum; Chlorides; Drug Synergism; Ions; Kinetics; Male; Muscimol; Osmolar Concentration; Oxazoles; Potassium; Rats; Rats, Inbred Strains; Synaptosomes | 1983 |
Ionic mechanisms of neuronal excitation by inhibitory GABAA receptors.
Topics: Acetazolamide; Amiloride; Animals; Bicarbonates; Chlorides; Dendrites; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Magnesium; Membrane Potentials; Muscimol; Neurons; Pyramidal Cells; Rats; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synapses | 1995 |
Prenatal lorazepam exposure: 4. Persistent alterations in pentylenetetrazole-induced seizure threshold and GABA-dependent chloride uptake after prenatal lorazepam exposure.
Topics: Animals; Brain Chemistry; Chlorides; Chlorine; Female; gamma-Aminobutyric Acid; Lorazepam; Mice; Muscimol; Pentylenetetrazole; Pregnancy; Prenatal Exposure Delayed Effects; Radioisotopes; Seizures | 1995 |
Enhancement of gamma-aminobutyric acidA receptor function and binding by the volatile anesthetic halothane.
Topics: Animals; Brain; Chloride Channels; Chlorides; Chlorine; Drug Synergism; Halothane; Ion Channels; Ionophores; Membrane Proteins; Muscimol; Protein Binding; Radioisotopes; Rats; Receptors, GABA-A; Stimulation, Chemical | 1993 |
Alterations in the brain GABAA/benzodiazepine receptor-chloride ionophore complex in a genetic model of paroxysmal dystonia: a quantitative autoradiographic analysis.
Topics: Animals; Autoradiography; Binding Sites; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Cricetinae; Dystonia; Flunitrazepam; Ionophores; Male; Models, Genetic; Muscimol; Radiography; Receptors, GABA-A | 1995 |
GABAA/benzodiazepine receptors in acutely isolated hippocampal astrocytes.
Topics: Amino Acid Sequence; Animals; Antibody Specificity; Astrocytes; Bicuculline; Brain; Calcium; Calcium Channels; Carbolines; Cell Separation; Chlorides; Diazepam; Evoked Potentials; gamma-Aminobutyric Acid; Gene Expression; Glial Fibrillary Acidic Protein; Hippocampus; Immunoblotting; In Vitro Techniques; Macromolecular Substances; Membrane Potentials; Molecular Sequence Data; Muscimol; Patch-Clamp Techniques; Peptide Fragments; Picrotoxin; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1995 |
Opposite changes in GABAA receptor function in the CA1-3 area and fascia dentata of kindled rat hippocampus.
Topics: Animals; Chlorides; Hippocampus; Kindling, Neurologic; Male; Microscopy, Electron; Muscimol; Osmolar Concentration; Rats; Rats, Wistar; Receptors, GABA; Seizures; Synaptosomes; Time Factors; Tissue Distribution | 1995 |
Functional diversity of GABAA receptor ligand-gated chloride channels in rat synaptoneurosomes.
Topics: Animals; Bicuculline; Brain; Chloride Channels; Chlorides; Desoxycorticosterone; Ion Channel Gating; Ligands; Male; Muscimol; Pentobarbital; Rats; Rats, Wistar; Receptors, GABA-A; Synaptosomes; Tissue Distribution | 1995 |
The effect of cyclopyrrolones on GABAA receptor function is different from that of benzodiazepines.
Topics: Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Benzodiazepines; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chlorides; Chlorine; Flumazenil; Hypnotics and Sedatives; Kinetics; Male; Mice; Mice, Inbred Strains; Muscimol; Naphthyridines; Piperazines; Radioisotopes; Receptors, GABA-A; Sulfur Compounds; Sulfur Radioisotopes; Tritium | 1994 |
Gamma-aminobutyric acidA receptor function is inhibited by microtubule depolymerization.
Topics: Animals; Biological Transport; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Chlorides; Colchicine; Convulsants; Dose-Response Relationship, Drug; Flunitrazepam; Histones; Humans; Lumicolchicines; Membranes; Mice; Microtubules; Muscimol; Nocodazole; Paclitaxel; Phosphorylation; Receptors, GABA-A; Vinblastine; Xenopus | 1994 |
Age-related changes of GABA-activated chloride channel properties in brain cortex synaptic plasma membrane: evidence for phospholipase involvement.
Topics: Aging; Animals; Arachidonic Acid; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chloride Channels; Chlorides; Convulsants; Diglycerides; gamma-Aminobutyric Acid; Kinetics; Muscimol; Phospholipases; Picrotoxin; Rats; Rats, Wistar; Sulfur Radioisotopes; Synaptic Membranes; Synaptosomes | 1994 |
Development pattern of the GABAA-benzodiazepine receptor ionophore complex in primary cultures of cortical neurons.
Topics: Affinity Labels; Animals; Azides; Benzodiazepines; Cells, Cultured; Cerebral Cortex; Chlorides; Flumazenil; Flunitrazepam; Mice; Mice, Inbred C57BL; Muscimol; Neurons; Receptors, GABA-A | 1994 |
Bidirectional modulation of GABA-gated chloride channels by divalent cations: inhibition by Ca2+ and enhancement by Mg2+.
Topics: Animals; Calcium; Calcium Channel Blockers; Cations, Divalent; Cerebral Cortex; Chloride Channels; Chlorides; gamma-Aminobutyric Acid; Ion Channel Gating; Magnesium; Male; Muscimol; Rats; Rats, Sprague-Dawley; Synaptosomes; Zinc | 1994 |
A novel GABA receptor on bipolar cell terminals in the tiger salamander retina.
Topics: Animals; Bicuculline; Chlorides; Crotonates; Electrophysiology; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Muscimol; Pentobarbital; Picrotoxin; Pyridazines; Receptors, GABA; Receptors, GABA-A; Retina; Retinal Ganglion Cells; Urodela | 1994 |
Modulatory action of arachidonic acid on GABAA/chloride channel receptor function in adult and aged brain cortex membranes.
Topics: Aging; Animals; Arachidonic Acid; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cerebral Cortex; Chloride Channels; Chlorides; Convulsants; Docosahexaenoic Acids; Fatty Acids, Nonesterified; Kinetics; Male; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A; Stearic Acids; Synaptic Membranes; Synaptosomes | 1993 |
Reconstitution of purified GABAA receptors: ligand binding and chloride transporting properties.
Topics: Animals; Bicuculline; Biological Transport; Brain Chemistry; Cattle; Chlorides; Chromatography, Affinity; Dose-Response Relationship, Drug; Flow Injection Analysis; Flunitrazepam; Ligands; Liposomes; Membrane Proteins; Muscimol; Picrotoxin; Quinolinium Compounds; Receptors, GABA-A | 1994 |
GABA-activated chloride channels in secretory nerve endings.
Topics: Animals; Bicuculline; Chlordiazepoxide; Chloride Channels; Chlorides; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Membrane Potentials; Membrane Proteins; Muscimol; Nerve Endings; Picrotoxin; Pituitary Gland, Posterior; Rats; Receptors, GABA-A | 1993 |
GABAA receptor function in the gamma-hydroxybutyrate model of generalized absence seizures.
Topics: Aminocaproates; Animals; Anticonvulsants; Brain Chemistry; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Chlorine; Convulsants; Electroencephalography; Epilepsy, Absence; Flunitrazepam; In Vitro Techniques; Kinetics; Male; Muscimol; Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sodium Oxybate; Synaptosomes; Vigabatrin | 1993 |
Barbiturate-benzodiazepine interactions at the gamma-aminobutyric acidA receptor in rat cerebral cortical synaptoneurosomes.
Topics: Animals; Barbiturates; Benzodiazepines; Cerebral Cortex; Chlorides; Dose-Response Relationship, Drug; Drug Interactions; Male; Muscimol; Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Reflex | 1993 |
Novel GABA responses from rod-driven retinal horizontal cells.
Topics: Animals; Bicuculline; Chlorides; Crotonates; Diazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Muscimol; Pentobarbital; Perches; Photoreceptor Cells; Receptors, GABA; Retina | 1993 |
Propofol produces differences in behavior but not chloride channel function between selected lines of mice.
Topics: Anesthetics, Intravenous; Animals; Brain; Central Nervous System; Central Nervous System Depressants; Chloride Channels; Chlorides; Dose-Response Relationship, Drug; Ethanol; GABA Agonists; Male; Mice; Mice, Inbred Strains; Muscimol; Posture; Propofol; Receptors, GABA; Reflex; Sleep | 1996 |
Zinc modulation of GABAA receptor-mediated chloride flux in rat hippocampal slices.
Topics: Animals; Chelating Agents; Chlorides; Dentate Gyrus; Ethylenediamines; In Vitro Techniques; Male; Muscimol; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Zinc Compounds | 1995 |
Optical imaging of intracellular chloride in living brain slices.
Topics: Animals; Animals, Newborn; Cell Membrane Permeability; Cerebellum; Cerebral Cortex; Chlorides; Dose-Response Relationship, Drug; Fluorescent Dyes; GABA Agonists; gamma-Aminobutyric Acid; Hippocampus; Microscopy, Confocal; Microscopy, Fluorescence; Muscimol; Neurons; Organ Culture Techniques; Pyramidal Cells; Quinolinium Compounds; Rats | 1995 |
Microtubule depolymerization inhibits ethanol-induced enhancement of GABAA responses in stably transfected cells.
Topics: Animals; Cattle; Cell Line; Chlorides; Colchicine; Ethanol; Flunitrazepam; Humans; Mice; Microtubules; Muscimol; Pentobarbital; Polymers; Receptor Aggregation; Receptors, GABA-A; Transfection | 1996 |
Role of chloride-homeostasis in the inhibitory control of neuronal network oscillators.
Topics: Animals; Cells, Cultured; Chlorides; Diuretics; Furosemide; GABA Agonists; Homeostasis; Mesencephalon; Muscimol; Nerve Net; Neurons; Rats; Receptors, AMPA; Receptors, GABA-A | 1996 |
Persistent reduction of GABA(A) receptor-mediated inhibition in rat hippocampus after chronic intermittent ethanol treatment.
Topics: Animals; Brain; Chlorides; Drug Administration Schedule; Electric Stimulation; Electrophysiology; Ethanol; GABA Agonists; Hippocampus; Male; Muscimol; Neural Inhibition; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Reference Values; Substance Withdrawal Syndrome; Tissue Distribution | 1996 |
Signaling pathway downstream of GABAA receptor in the growth cone.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Axons; Binding Sites; Calcium; Chlorides; Diazepam; Fetus; gamma-Aminobutyric Acid; GTPase-Activating Proteins; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Models, Neurological; Muscimol; Myristoylated Alanine-Rich C Kinase Substrate; Neurites; Picrotoxin; Prosencephalon; Proteins; Rats; Rats, Wistar; Receptors, GABA-A; Signal Transduction; Verapamil | 1996 |
Inhibition of GABAA ligand-gated Cl- channels by zinc in adult rat brain: a regional study.
Topics: Animals; Azides; Benzodiazepines; Brain; Cerebellum; Cerebral Cortex; Chloride Channels; Chlorides; Diazepam; Hippocampus; Ion Channel Gating; Kinetics; Male; Muscimol; Organ Specificity; Radioligand Assay; Rats; Rats, Wistar; Receptors, GABA-A; Synaptosomes; Tritium; Zinc | 1996 |
Is upregulation of benzodiazepine receptors a compensatory reaction to reduced GABAergic tone in the brain of stressed mice?
Topics: Animals; Brain; Chlorides; Flunitrazepam; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Receptors, GABA-A; Stress, Physiological; Thiopental; Up-Regulation | 1996 |
Ro 15-4513 potentiates, instead of antagonizes, ethanol-induced sleep in mice exposed to small platform stress.
Topics: Animals; Anxiety; Azides; Benzodiazepines; Central Nervous System Depressants; Cerebellum; Chlorides; Diazepam; Drug Synergism; Ethanol; GABA Agonists; GABA Modulators; Male; Mice; Muscimol; Receptors, GABA-A; Sleep; Stress, Psychological | 1996 |
Two types of identified ascending interneurons with distinct GABA receptors in the crayfish terminal abdominal ganglion.
Topics: Animals; Astacoidea; Bicuculline; Chlorides; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Invertebrate; In Vitro Techniques; Interneurons; Male; Muscimol; Muscles; Picrotoxin; Receptors, GABA | 1997 |
GABA(A) receptor activation triggers a Cl- conductance increase and a K+ channel blockade in cerebellar granule cells.
Topics: Animals; Barium; Bicuculline; Cells, Cultured; Cerebellum; Chloride Channels; Chlorides; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Mice; Mice, Inbred Strains; Muscimol; Neurons; Patch-Clamp Techniques; Picrotoxin; Potassium Channel Blockers; Receptors, GABA-A; Time Factors | 1997 |
Synaptoneurosomes. A preparation for studying subhippocampal GABAA receptor activity.
Topics: Animals; Cell Fractionation; Centrifugation; Chlorides; GABA Agonists; Hippocampus; Male; Microscopy, Electron; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A; Subcellular Fractions; Synaptosomes | 1997 |
Characterization of chloride efflux from GT1-7 neurons: lack of effect of ethanol on GABAA response.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Bicuculline; Bumetanide; Cells, Cultured; Central Nervous System Stimulants; Chlorides; Diuretics; Ethanol; GABA Agonists; GABA Antagonists; GABA Modulators; Mice; Muscimol; Neurons; Pentobarbital; Receptors, GABA-A; Temperature | 1998 |
Opposing effects of different steroid sulfates on GABAA receptor-mediated chloride uptake.
Topics: Animals; Biological Transport; Cerebral Cortex; Chlorides; Dehydroepiandrosterone Sulfate; GABA Agonists; GABA Modulators; GABA-A Receptor Agonists; In Vitro Techniques; Ionophores; Male; Muscimol; Pregnanolone; Pregnenolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synaptosomes | 1998 |
Astrocytes regulate developmental changes in the chloride ion gradient of embryonic rat ventral spinal cord neurons in culture.
Topics: Animals; Astrocytes; Bicuculline; Calcium; Calcium Channel Blockers; Cells, Cultured; Chloride Channels; Chlorides; Culture Media, Conditioned; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Microscopy, Video; Muscimol; Neurons; Nifedipine; Patch-Clamp Techniques; Rats; Receptors, GABA-A; Spinal Cord; Time Factors | 1998 |
Molecular and functional adaptation of the GABA(A) receptor complex during pregnancy and after delivery in the rat brain.
Topics: Allosteric Regulation; Alternative Splicing; Animals; Brain Chemistry; Cerebral Cortex; Chlorides; Diazepam; Female; Hippocampus; Isotopes; Muscimol; Postpartum Period; Pregnancy; Pregnancy, Animal; Pregnanolone; Protein Isoforms; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; RNA, Messenger | 1998 |
Role of brain allopregnanolone in the plasticity of gamma-aminobutyric acid type A receptor in rat brain during pregnancy and after delivery.
Topics: Animals; Cell Membrane; Cerebral Cortex; Chlorides; Desoxycorticosterone; Estrus; Female; Finasteride; Gene Expression Regulation; Hippocampus; Muscimol; Postpartum Period; Pregnancy; Pregnancy, Animal; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; RNA, Messenger; Time Factors; Transcription, Genetic | 1998 |
Synaptic inhibition in the isolated respiratory network of neonatal rats.
Topics: Action Potentials; Animals; Animals, Newborn; Anti-Bacterial Agents; Baclofen; Bicarbonates; Bicuculline; Carbon Dioxide; Chloride Channel Agonists; Chloride Channels; Chlorides; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glycine Agents; Gramicidin; Medulla Oblongata; Microdialysis; Muscimol; Neural Inhibition; Neurons; Patch-Clamp Techniques; Rats; Receptors, GABA-B; Respiration; Strychnine; Synapses; Tetrodotoxin | 1998 |
The K+/Cl- co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation.
Topics: Animals; Blotting, Southern; Carrier Proteins; Cell Differentiation; Chlorides; Electrophysiology; GABA Agonists; gamma-Aminobutyric Acid; Gene Expression Regulation, Developmental; Guinea Pigs; Hippocampus; In Vitro Techniques; K Cl- Cotransporters; Muscimol; Potassium; Pyramidal Cells; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Symporters | 1999 |
A reexamination of the role of GABA in the mammalian suprachiasmatic nucleus.
Topics: Action Potentials; Animals; Bicuculline; Cell Membrane Permeability; Chlorides; Circadian Rhythm; Dose-Response Relationship, Drug; Electrophysiology; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Gramicidin; In Vitro Techniques; Male; Muscimol; Neurons; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Suprachiasmatic Nucleus | 1999 |
Mechanism by which GABA, through its GABA(A) receptor, modulates glutamate release from rat cortical neurons in culture.
Topics: Animals; Barbiturates; Calcium; Cells, Cultured; Cerebral Cortex; Chloride Channels; Chlorides; Fluorescence; Fluorescent Dyes; gamma-Aminobutyric Acid; Glutamic Acid; Ion Transport; Isoxazoles; Membrane Potentials; Muscimol; Neurons; Potassium Chloride; Rats; Receptors, GABA-A | 1999 |
Fluorescence imaging of GABAA receptor-mediated intracellular [Cl-] in P19-N cells reveals unique pharmacological properties.
Topics: Animals; Central Nervous System Depressants; Chlorides; Diazepam; DNA Primers; Ethanol; Flunitrazepam; Fluorescent Dyes; GABA Agonists; GABA Modulators; Gene Expression; Mice; Muscimol; Neoplastic Stem Cells; Neuroglia; Pentobarbital; Pregnanolone; Quinolinium Compounds; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tritium | 1999 |
GABAA receptor agonists modulate K+ currents in adult hippocampal glial cells in situ.
Topics: Aging; Animals; Animals, Newborn; Bicuculline; Chlorides; Electric Conductivity; GABA Antagonists; GABA-A Receptor Agonists; Hippocampus; In Vitro Techniques; Muscimol; Neuroglia; Patch-Clamp Techniques; Potassium; Rats; Rats, Wistar; Receptors, GABA-A | 1999 |
Evidence for chloride ions as intracellular messenger substances in astrocytes.
Topics: Animals; Animals, Newborn; Astrocytes; Barium; Cells, Cultured; Chloride Channels; Chlorides; Gluconates; Hippocampus; Kinetics; Muscimol; Potassium Channels; Rats; Rats, Wistar; Receptors, GABA-A; Second Messenger Systems; Sodium | 1999 |
Structural requirements for the interaction of unsaturated free fatty acids with recombinant human GABAA receptor complexes.
Topics: Binding, Competitive; Cell Line; Chlorides; Electrophysiology; Fatty Acids, Nonesterified; GABA Agonists; Humans; Ion Channel Gating; Muscimol; Receptors, GABA-A; Recombinant Proteins | 1999 |
Zinc inhibition of gamma-aminobutyric acid(A) receptor function is decreased in the cerebral cortex during pilocarpine-induced status epilepticus.
Topics: Animals; Biological Transport; Cerebellum; Cerebral Cortex; Chlorides; GABA Agonists; GABA-A Receptor Antagonists; Male; Muscarinic Agonists; Muscimol; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Status Epilepticus; Zinc | 1999 |
Optical imaging reveals elevated intracellular chloride in hippocampal pyramidal neurons after oxidative stress.
Topics: 2-Amino-5-phosphonovalerate; Animals; Antioxidants; Cell Membrane Permeability; Chlorides; Chromans; Deferoxamine; Extracellular Space; Fluorescent Dyes; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Hydrogen Peroxide; In Vitro Techniques; Kinetics; Microscopy, Confocal; Muscimol; Nipecotic Acids; Oxidative Stress; Pyramidal Cells; Quinolinium Compounds; Quinoxalines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tiagabine | 1999 |
GABAA receptor mediated elevation of Ca2+ and modulation of gonadotrophin-releasing hormone action in alphaT3-1 gonadotropes.
Topics: Anesthetics; Animals; Baclofen; Bicuculline; Biological Transport; Calcium; Calcium Channel Blockers; Cells, Cultured; Chlorides; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Mice; Muscimol; Nifedipine; Picrotoxin; Pituitary Gland; Pregnanediones; Receptors, GABA-A; Receptors, GABA-B | 2000 |
Perturbation by the PCB mixture aroclor 1254 of GABA(A) receptor-mediated calcium and chloride responses during maturation in vitro of rat neocortical cells.
Topics: Animals; Antithyroid Agents; Calcium; Cells, Cultured; Chlorides; Chlorodiphenyl (54% Chlorine); Drug Interactions; Fluorescent Dyes; Fura-2; GABA Agonists; Muscimol; Neocortex; Polychlorinated Biphenyls; Rats; Rats, Long-Evans; Receptors, GABA-A | 2000 |
Early postnatal maturation of GABAA-mediated inhibition in the brainstem respiratory rhythm-generating network of the mouse.
Topics: Action Potentials; Animals; Bicarbonates; Bicuculline; Chlorides; Female; GABA Agonists; GABA Antagonists; Male; Mice; Mice, Inbred Strains; Muscimol; Neural Inhibition; Neurons; Patch-Clamp Techniques; Periodicity; Receptors, GABA-A; Respiratory Center | 2000 |
Activation of GABA(A) receptors in subthalamic neurons in vitro: properties of native receptors and inhibition mechanisms.
Topics: Animals; Bicarbonates; Bicuculline; Chlorides; Diazepam; Electrophysiology; Flunitrazepam; GABA Agonists; GABA Antagonists; GABA Modulators; Membrane Potentials; Muscimol; Neural Inhibition; Neurons; Organ Culture Techniques; Pentobarbital; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Sesterterpenes; Subthalamic Nucleus | 2001 |
Contribution of the Na-K-Cl cotransporter on GABA(A) receptor-mediated presynaptic depolarization in excitatory nerve terminals.
Topics: Animals; Bumetanide; Carrier Proteins; Chlorides; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Hypothalamus; In Vitro Techniques; Muscimol; Neurons; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, GABA-A; Sodium-Potassium-Chloride Symporters; Synaptic Transmission; Tetrodotoxin; Ventromedial Hypothalamic Nucleus | 2001 |
The motor inhibitory system operating during active sleep is tonically suppressed by GABAergic mechanisms during other states.
Topics: Animals; Bicuculline; Carbachol; Cats; Chlorides; Cholinergic Agents; Electrophysiology; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Microinjections; Motor Neurons; Muscimol; Muscle Tonus; Neural Inhibition; Reflex; Reticular Formation; Sleep; Spinal Cord; Synapses | 2001 |
Transgenic mice expressing a pH and Cl- sensing yellow-fluorescent protein under the control of a potassium channel promoter.
Topics: Animals; Bacterial Proteins; Brain; Brain Chemistry; Chlorides; GABA Agonists; Glutamic Acid; Hydrogen-Ion Concentration; Luminescent Proteins; Mice; Mice, Transgenic; Microscopy, Confocal; Muscimol; Neurons; Potassium Channels; Potassium Channels, Voltage-Gated; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Shaw Potassium Channels | 2002 |
Reduction of KCC2 expression and GABAA receptor-mediated excitation after in vivo axonal injury.
Topics: Animals; Axons; Axotomy; Calcium; Chlorides; Diuretics; Fluorescent Dyes; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; In Situ Hybridization; In Vitro Techniques; K Cl- Cotransporters; Membrane Potentials; Motor Neurons; Muscimol; Nickel; Patch-Clamp Techniques; Rats; Receptors, GABA-A; RNA, Messenger; Sulfonamides; Symporters; Tetrodotoxin; Vagotomy | 2002 |
Molecular and pharmacological characterization of GABA(A) receptor alpha1 subunit knockout mice.
Topics: Animals; Autoradiography; Bicuculline; Blotting, Western; Cerebral Cortex; Chlorides; Convulsants; Female; GABA Agonists; GABA Antagonists; Kinetics; Ligands; Male; Mice; Mice, Knockout; Muscimol; Pyridazines; Radioligand Assay; Receptors, GABA-A; Seizures | 2002 |
Intracellular chloride modulates A-type potassium currents in astrocytes.
Topics: Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Chlorides; GABA-A Receptor Agonists; Intracellular Fluid; Muscimol; Potassium Channels, Voltage-Gated; Rats; Rats, Wistar; Receptors, GABA-A | 2002 |
GABA(A) receptor alpha-1 subunit deletion alters receptor subtype assembly, pharmacological and behavioral responses to benzodiazepines and zolpidem.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Benzodiazepines; Chlorides; Diazepam; Exploratory Behavior; Female; Flunitrazepam; GABA Agonists; GABA Modulators; Gene Deletion; Hypnotics and Sedatives; Male; Mice; Mice, Knockout; Motor Activity; Muscimol; Postural Balance; Pyridines; Radioligand Assay; Receptors, GABA-A; Seizures; Zolpidem | 2002 |
Activation of A-type gamma-aminobutyric acid receptors excites gonadotropin-releasing hormone neurons.
Topics: Action Potentials; Animals; Cell Line, Transformed; Chlorides; Electric Conductivity; Female; gamma-Aminobutyric Acid; Gene Expression; Gonadotropin-Releasing Hormone; Gramicidin; Green Fluorescent Proteins; Homeostasis; Immunohistochemistry; In Situ Hybridization; K Cl- Cotransporters; Luminescent Proteins; Male; Membrane Potentials; Mice; Mice, Transgenic; Muscimol; Neurons; Patch-Clamp Techniques; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Recombinant Fusion Proteins; RNA, Messenger; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Symporters | 2002 |
Cross talk between the GABA(A) receptor and the Na-K-Cl cotransporter is mediated by intracellular Cl-.
Topics: Animals; Calcium; Cell Size; Cells, Cultured; Cerebral Cortex; Chlorides; Female; GABA Agonists; Muscimol; Neurons; Phosphorylation; Potassium; Pregnancy; Rats; Rats, Sprague-Dawley; Receptor Cross-Talk; Receptors, GABA-A; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2 | 2003 |
Deletion of GABAA receptor alpha 1 subunit-containing receptors alters responses to ethanol and other anesthetics.
Topics: Anesthetics; Animals; Anxiety; Behavior, Animal; Bicuculline; Brain; Central Nervous System Depressants; Chlorides; Desoxycorticosterone; Drug Tolerance; Ethanol; Exploratory Behavior; Female; GABA Agonists; GABA Antagonists; Male; Mice; Mice, Knockout; Muscimol; Postural Balance; Pregnanolone; Receptors, GABA-A; Steroids | 2003 |
Effect of single injection of pentylenetetrazole in a subconvulsive dose on Cl- conductance of the GABAA-receptor complex.
Topics: Animals; Cerebral Cortex; Chloride Channels; Chlorides; Convulsants; Electric Conductivity; Epilepsy; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Injections; Male; Muscimol; Pentylenetetrazole; Rats; Rats, Wistar; Synaptosomes | 2004 |
Regulation of native GABAA receptors by PKC and protein phosphatase activity.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Analysis of Variance; Animals; Chlorides; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; GABA Agonists; gamma-Aminobutyric Acid; Isotopes; Male; Microcystins; Muscimol; Naphthalenes; Peptides, Cyclic; Phorbol 12,13-Dibutyrate; Phosphoprotein Phosphatases; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2005 |
Na+-K+-2Cl- cotransporters and Cl- channels regulate citric acid cough in guinea pigs.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Chloride Channels; Chlorides; Citric Acid; Cough; Furosemide; GABA-A Receptor Agonists; Guinea Pigs; Immunohistochemistry; Male; Muscimol; Neurons, Afferent; Niflumic Acid; Reflex; Respiration; Respiratory Mechanics; Respiratory Physiological Phenomena; Respiratory System; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Potassium-Chloride Symporters | 2006 |
Development of chloride-mediated inhibition in neurons of the anteroventral cochlear nucleus of gerbil (Meriones unguiculatus).
Topics: Animals; Brain Stem; Chlorides; Cochlear Nucleus; Electrophysiology; Furosemide; GABA Antagonists; gamma-Aminobutyric Acid; Gerbillinae; Glycine; Muscimol; Neurons; Pyridazines; Receptors, GABA-A; Synaptic Transmission | 2007 |
The Cav3.2/alpha1H T-type Ca2+ current is a molecular determinant of excitatory effects of GABA in adult sensory neurons.
Topics: Animals; Baclofen; Calcium; Calcium Channel Blockers; Calcium Channels, T-Type; Cells, Cultured; Chlorides; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Female; GABA Agonists; gamma-Aminobutyric Acid; Ganglia, Spinal; Membrane Potentials; Mice; Mice, Knockout; Muscimol; Neurons, Afferent; Nickel; Patch-Clamp Techniques | 2007 |
Sanjoinine A isolated from Zizyphi Spinosi Semen augments pentobarbital-induced sleeping behaviors through the modification of GABA-ergic systems.
Topics: Animals; Cerebellum; Chlorides; Drug Interactions; GABA Agonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hypnotics and Sedatives; Isoenzymes; Male; Mice; Mice, Inbred ICR; Muscimol; Pentobarbital; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sleep; Ziziphus | 2007 |
Characteristics of GABA receptors on the ocellar L-neurons of American cockroach Periplaneta americana.
Topics: Animals; Bicuculline; Chlorides; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Iontophoresis; Membrane Potentials; Muscimol; Neurons; Periplaneta; Picrotoxin; Receptors, GABA; Sodium Chloride | 2007 |
Cyclopeptide alkaloid fraction from Zizyphi Spinosi Semen enhances pentobarbital-induced sleeping behaviors.
Topics: Alkaloids; Animals; Cells, Cultured; Cerebellum; Chlorides; Drug Synergism; GABA Agonists; gamma-Aminobutyric Acid; Glyceraldehyde-3-Phosphate Dehydrogenases; Hypnotics and Sedatives; Male; Mice; Mice, Inbred ICR; Muscimol; Neurons; Pentobarbital; Plant Extracts; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sleep; Synaptic Transmission; Ziziphus | 2008 |
NKCC1 and KCC2 prevent hyperexcitability in the mouse hippocampus.
Topics: 4-Aminopyridine; Animals; Blotting, Western; Chlorides; Electrophysiology; Extracellular Space; GABA Agonists; Genotype; Hippocampus; In Vitro Techniques; K Cl- Cotransporters; Mice; Mice, Knockout; Muscimol; Neuroglia; Patch-Clamp Techniques; Potassium Channel Blockers; Pyramidal Cells; Seizures; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Symporters | 2008 |
Cl(-) conduction of GABAA receptor complex of synaptic membranes in the cortex of rats at the middle stage of chronic cerebral epileptization (pharmacological kindling).
Topics: Animals; Cerebral Cortex; Chlorides; Chronic Disease; Dose-Response Relationship, Drug; Epilepsy; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Kindling, Neurologic; Male; Muscimol; Pentylenetetrazole; Rats; Rats, Wistar; Receptors, GABA-A; Seizures; Synaptic Membranes | 2007 |
Sustained depolarizing shift of the GABA reversal potential by glutamate receptor activation in hippocampal neurons.
Topics: Analysis of Variance; Animals; Bumetanide; Calcium; Chlorides; Electric Stimulation; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Agents; Furosemide; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Membrane Potentials; Muscimol; Neural Inhibition; Neural Pathways; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Receptors, Glutamate; Sodium Potassium Chloride Symporter Inhibitors; Time Factors | 2008 |
Random stimulation of spider mechanosensory neurons reveals long-lasting excitation by GABA and muscimol.
Topics: Algorithms; Animals; Bumetanide; Carrier Proteins; Chlorides; Diuretics; Electric Stimulation; Furosemide; GABA Agonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Mechanotransduction, Cellular; Muscimol; Patch-Clamp Techniques; Physical Stimulation; Sensory Receptor Cells; Spiders | 2009 |
Inhibition of chloride outward transport by gadolinium in cultured rat spinal cord neurons.
Topics: Animals; Bumetanide; Cells, Cultured; Chlorides; Female; Furosemide; GABA-A Receptor Agonists; Gadolinium; K Cl- Cotransporters; Muscimol; Neurons; Pregnancy; Rats; Rats, Wistar; Receptors, GABA-A; Sodium Potassium Chloride Symporter Inhibitors; Solute Carrier Family 12, Member 2; Spinal Cord; Symporters | 2009 |
Cl- conduction of GABA(A)-receptor complex of synaptic membranes of rat brain cortex after development of chronic epileptization of the brain (pharmacological kindling).
Topics: Animals; Cerebral Cortex; Chlorides; Chlorine; Kindling, Neurologic; Male; Muscimol; Pentylenetetrazole; Radioisotopes; Rats; Rats, Wistar; Receptors, GABA-A; Synaptic Membranes | 2008 |
Novel protective effect of mifepristone on detrimental GABAA receptor activity to immature Purkinje neurons.
Topics: Animals; Caffeine; Chlorides; gamma-Aminobutyric Acid; Imidazoles; Mice; Mifepristone; Muscimol; p38 Mitogen-Activated Protein Kinases; Purkinje Cells; Pyrimidines; Receptors, GABA-A | 2011 |
(-)-epigallocatechin-3-O-gallate augments pentobarbital-induced sleeping behaviors through Cl- channel activation.
Topics: Animals; Catechin; Cells, Cultured; Cerebellum; Chloride Channels; Chlorides; Glutamate Decarboxylase; Hippocampus; Male; Mice; Mice, Inbred ICR; Muscimol; Neuroprotective Agents; Pentobarbital; Rats; Rats, Sprague-Dawley; Receptors, GABA; Sleep | 2011 |
Adenosine release during seizures attenuates GABAA receptor-mediated depolarization.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Animals; CA3 Region, Hippocampal; Chlorides; Epilepsy, Temporal Lobe; GABA Agonists; Gramicidin; In Vitro Techniques; Male; Membrane Potentials; Muscimol; Neural Conduction; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar; Receptors, GABA-A; Seizures; Signal Transduction; Tetrodotoxin | 2012 |
Modulation of spinal GABAergic analgesia by inhibition of chloride extrusion capacity in mice.
Topics: Analgesia; Analgesics; Animals; Benzodiazepines; Chlorides; GABA-A Receptor Agonists; Isoxazoles; K Cl- Cotransporters; Male; Mice; Mice, Inbred ICR; Muscimol; Neuralgia; Peripheral Nerve Injuries; Pregnanolone; Receptors, GABA-A; Sciatic Nerve; Symporters | 2012 |
Excitatory actions of GABA in developing chick vestibular afferents: effects on resting electrical activity.
Topics: Action Potentials; Animals; Chick Embryo; Chloride Channels; Chlorides; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Muscimol; Neurons, Afferent; Vestibular Nerve | 2013 |
Disrupted Cl(-) homeostasis contributes to reductions in the inhibitory efficacy of diazepam during hyperexcited states.
Topics: Animals; Cells, Cultured; Chlorides; Diazepam; Furosemide; GABA Modulators; Glutamic Acid; Homeostasis; K Cl- Cotransporters; Muscimol; Neural Inhibition; Propofol; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Sodium Potassium Chloride Symporter Inhibitors; Symporters | 2013 |
3,4,5-Trimethoxycinnamic acid (TMCA), one of the constituents of Polygalae Radix enhances pentobarbital-induced sleeping behaviors via GABAAergic systems in mice.
Topics: Animals; Cerebellum; Chlorides; Cinnamates; Drug Synergism; GABA Agonists; GABAergic Neurons; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hypnotics and Sedatives; Male; Mice; Motor Activity; Muscimol; Neurons; Pentobarbital; Polygala; Primary Cell Culture; Receptors, GABA-A; Sleep; Sleep Stages | 2013 |
Chloride Accumulators NKCC1 and AE2 in Mouse GnRH Neurons: Implications for GABAA Mediated Excitation.
Topics: Animals; Bicarbonates; Bumetanide; Chloride-Bicarbonate Antiporters; Chlorides; Female; Gonadotropin-Releasing Hormone; Membrane Potentials; Membrane Transport Proteins; Mice; Muscimol; Neurons; Receptors, GABA-A; Sexual Maturation; Solute Carrier Family 12, Member 2 | 2015 |
Alcohol preference and consumption are controlled by the caudal linear nucleus in alcohol-preferring rats.
Topics: Alcohol Drinking; Animals; Bicuculline; Brain; Chlorides; Ethanol; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Magnetic Resonance Imaging; Male; Manganese Compounds; Muscimol; Raphe Nuclei; Rats; Rats, Wistar; Receptors, GABA-A | 2016 |
GABA is an inhibitory neurotransmitter in the neural circuit regulating metamorphosis in a marine snail.
Topics: Aminooxyacetic Acid; Animals; Anions; Bicuculline; Chlorides; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Larva; Metamorphosis, Biological; Muscimol; Neurotransmitter Agents; Pyridazines; Receptors, GABA-A; Serotonin; Snails | 2018 |
Effects of bile duct ligation on the inhibitory control of supraoptic vasopressin neurons.
Topics: Animals; Arginine Vasopressin; Bile Ducts; Chlorides; gamma-Aminobutyric Acid; Green Fluorescent Proteins; Hyponatremia; Liver Cirrhosis; Male; Muscimol; Neurons; Rats; Rats, Sprague-Dawley; Supraoptic Nucleus; Vasopressins | 2023 |
Characterization of antagonistic activity and binding properties of SR 95531, a pyridazinyl-GABA derivative, in rat brain and cultured cerebellar neuronal cells.
Topics: Animals; Brain; Cells, Cultured; Cerebellum; Cerebral Cortex; Chlorine; GABA Antagonists; Kinetics; Male; Muscimol; Neurons; Pyridazines; Rats; Rats, Inbred Strains; Synaptosomes | 1992 |
Cerebellar GABAB receptors modulate function of GABAA receptors.
Topics: Animals; Baclofen; Barium; Calcium; Cells, Cultured; Cerebellum; Cerebral Cortex; Chlorine; Dose-Response Relationship, Drug; Estrenes; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Mice; Mice, Inbred ICR; Muscimol; Pyrrolidinones; Receptors, GABA-A; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors; Type C Phospholipases | 1991 |
Tyrosine kinase phosphorylation of GABAA receptors.
Topics: Animals; Brain; Cattle; Chlorine; Cytoplasm; Escherichia coli; GABA-A Receptor Agonists; Liposomes; Male; Mice; Mice, Inbred ICR; Muscimol; Oncogene Protein pp60(v-src); Peptide Fragments; Phosphorylation; Radioisotopes; Receptors, GABA-A; Recombinant Proteins; Xenopus laevis | 1995 |
Studies on picrotoxin binding sites of GABAA receptors in rat cortical synaptoneurosomes.
Topics: Animals; Binding Sites; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chlorine; Desoxycorticosterone; Diazepam; In Vitro Techniques; Male; Membranes; Muscimol; Pentobarbital; Picrotoxin; Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Steroids; Synaptosomes | 1994 |
The enhancement of muscimol-stimulated 36C1 influx by the antispastic 5-aryl-3-(alkylsulfonyl)-4H-1,2,4-triazole (MDL 27,531) in rat brain membrane vesicles.
Topics: Animals; Brain Chemistry; Chloride Channels; Chlorine; Flunitrazepam; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Ion Channel Gating; Male; Membranes; Muscimol; Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Triazoles | 1995 |
Inhibition of GABAA receptor chloride channel by quinolones and norfloxacin-biphenylacetic acid hybrid compounds.
Topics: Animals; Anti-Infective Agents; Chloride Channels; Chlorine; Enoxacin; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; Male; Muscimol; Norfloxacin; Phenylacetates; Pyridazines; Quinolones; Rats; Rats, Wistar; Synaptosomes | 1996 |
Mechanism-based modeling of adaptive changes in the pharmacodynamics of midazolam in the kindling model of epilepsy.
Topics: Adaptation, Physiological; Animals; Anticonvulsants; Brain; Chlorine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Electroencephalography; Epilepsy; GABA Agonists; In Vitro Techniques; Kindling, Neurologic; Male; Midazolam; Muscimol; Radioligand Assay; Rats; Rats, Wistar; Synaptic Transmission; Synaptosomes | 1999 |
Effects of the chlorotriazine herbicide, cyanazine, on GABA(A) receptors in cortical tissue from rat brain.
Topics: Animals; Azides; Benzodiazepines; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chloride Channels; Chlorine; GABA Agonists; Herbicides; Male; Muscimol; Radioisotopes; Rats; Rats, Long-Evans; Receptors, GABA-A; Synaptosomes; Triazines | 1999 |
Mechanism-based modeling of functional adaptation upon chronic treatment with midazolam.
Topics: Adaptation, Physiological; Animals; Biological Transport; Brain Chemistry; Chlorine; Dose-Response Relationship, Drug; Electroencephalography; Flunitrazepam; GABA Agonists; GABA Modulators; Male; Midazolam; Models, Biological; Muscimol; Radioligand Assay; Rats; Rats, Wistar; Receptors, GABA-A; Tritium | 2000 |
Age-related differences in neurosteroid potentiation of muscimol-stimulated 36Cl(-) flux following chronic ethanol treatment.
Topics: Adolescent; Aging; Alcohol-Induced Disorders, Nervous System; Animals; Anti-Anxiety Agents; Brain; Chloride Channels; Chlorine; Chronic Disease; Desoxycorticosterone; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Ethanol; GABA Agonists; Humans; Male; Muscimol; Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synaptosomes | 2001 |
3Alpha-hydroxy-5alpha-pregnan-20-one levels and GABA(A) receptor-mediated 36Cl(-) flux across development in rat cerebral cortex.
Topics: Allosteric Regulation; Animals; Animals, Newborn; Anti-Anxiety Agents; Biological Transport; Cerebral Cortex; Chlorine; Desoxycorticosterone; Female; Flunitrazepam; GABA Agonists; GABA Modulators; Labor, Obstetric; Male; Muscimol; Pregnancy; Pregnanolone; Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sex Characteristics | 2001 |
Methanol extract of Longanae Arillus augments pentobarbital-induced sleep behaviors through the modification of GABAergic systems.
Topics: Animals; Chlorine; Drug Synergism; GABA Modulators; Glutamate Decarboxylase; Hypnotics and Sedatives; Male; Mice; Mice, Inbred ICR; Muscimol; Pentobarbital; Plant Extracts; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sapindaceae; Sleep | 2009 |
Depolarizing chloride gradient in developing cochlear nucleus neurons: underlying mechanism and implication for calcium signaling.
Topics: Animals; Bumetanide; Calcium Channels; Calcium Signaling; Chlorine; Cochlear Nucleus; Extracellular Space; Female; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Gerbillinae; In Vitro Techniques; Intracellular Space; Male; Membrane Potentials; Models, Neurological; Muscimol; Neurons; Sodium; Sodium Potassium Chloride Symporter Inhibitors; Solute Carrier Family 12, Member 2 | 2014 |