Page last updated: 2024-09-03

muristerone a and ecdysterone

muristerone a has been researched along with ecdysterone in 57 studies

Compound Research Comparison

Studies
(muristerone a)
Trials
(muristerone a)
Recent Studies (post-2010)
(muristerone a)
Studies
(ecdysterone)
Trials
(ecdysterone)
Recent Studies (post-2010) (ecdysterone)
60051,83010560

Protein Interaction Comparison

ProteinTaxonomymuristerone a (IC50)ecdysterone (IC50)
UltraspiracleNezara viridula (southern green stink bug)2.849
20-hydroxy-ecdysone receptor Nezara viridula (southern green stink bug)2.849
Ecdysone receptorLucilia cuprina (Australian sheep blowfly)5.5
Protein ultraspiracleDrosophila melanogaster (fruit fly)0.0457
Ecdysone receptorDrosophila melanogaster (fruit fly)0.0457
Ultraspiracle Leptinotarsa decemlineata (Colorado potato beetle)0.4365
20-hydroxy-ecdysone receptor Leptinotarsa decemlineata (Colorado potato beetle)0.4365
Ultraspiracle protein Spodoptera frugiperda (fall armyworm)0.166
20-hydroxy-ecdysone receptor Spodoptera frugiperda (fall armyworm)0.166

Research

Studies (57)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.75)18.7374
1990's20 (35.09)18.2507
2000's30 (52.63)29.6817
2010's6 (10.53)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Graham, LD; Hannan, GN; Hill, RJ; Lawrence, MC; Simpson, AM; Tohidi-Esfahani, D1
Báthori, M; Béni, Z; Hunyadi, A; Martins, A; Molnár, J; Tóth, N; Ványolós, A; Zupkó, I1
Landon, TM; O'Connor, JD; Sage, BA; Seeler, BJ1
Evans, RM; McKeown, M; Yao, TP; Zelhof, AC1
Chen, JD; Cherbas, L; Cherbas, P; Evans, RM; Forman, BM; Jiang, Z; McKeown, M; Yao, TP1
Stewart, AF; Stunnenberg, HG; Thomas, HE1
Evans, RM; No, D; Yao, TP1
Chen, ST; Farber, JL; Pastorino, JG; Snyder, JW; Tafani, M1
Elke, C; Imhof, MO; Lezzi, M; Vögtli, M1
Brown, MS; Goldstein, JL; Guryev, O; Pai, JT1
Kakar, SS1
Monks, B; Morris, RJ; Sawicki, JA1
Gunn, RB; Timmer, RT1
Johns, DC; Mains, RE; Marbán, E; Marx, R; O'Rourke, B1
Gil, J; Perucho, M; Reed, JC; Yamamoto, H; Zapata, JM1
Drayton, P; Greenland, A; Jepson, I; Martinez, A; Sparks, C; Thompson, J1
Lengyel, P; Liu, CJ; Wang, H1
Blandino, G; Givol, D; Wang, Y1
Hara, M; Itoh, N; Kamada, H; Noguchi, A; Ohshima, TA; Saito, I; Saruta, K; Sawa, H1
Baniahmad, A; Renkawitz, R; Tenbaum, SP; Thormeyer, D1
Johns, DC; Marban, E; Nuss, HB1
Broad, P; Greenland, AJ; Gross, B; Jepson, I; Martinez, A; Palli, SR; Perara, SC; Pongs, O; Scanlon, D; Windass, J1
Bianchi, V; Ferraro, P; Gallinaro, L; Gazziola, C; Moras, M; Rampazzo, C; Reichard, P; Verin, R1
Choi, DS; Sadée, W; Tolbert, L; Wang, D1
Donjerković, D; Mueller, CM; Scott, DW1
Charles, lG; Liu, L; Smith, GC; Xu, W1
Franz, T; Jess, N; Lüers, GH1
Banayo, E; Cho, GJ; Eshelman, B; Evans, RM; Koder, A; Nelson, MC; Saez, E1
Lin, G; Stern, R1
Carey, GB; Donjerković, D; Liu, S; Mueller, CM; Scott, DW1
Duquesne, F; Florent, M; Roué, G; Sola, B; Troussard, X1
Barlow, M; Chang, D; Evans, GR; Gurtner, G; Koutz, C; Patrick, CW; Schmidt, M; Wu, X; Zheng, B1
Cole, SL; Humphrey, PP; Schindler, M; Sellers, LA1
Dagon, Y; Dovrat, S; Hacohen, D; Nir, U; Salzberg, S; Shlomo, G; Sredni, B; Vilchik, S1
Hara, M; Ito, N; Nagane, M; Noguchi, A; Saito, I; Sawa, H1
Amarante-Mendes, GP; Brumatti, G; Lotfi, CF; Marchetto, MC; Menck, CF; Muotri, AR; Okazaki, K; Suzuki, MF1
Bergman, T; Frömel, C; Grebe, M; Henrich, VC; Lezzi, M; Przibilla, S; Spindler-Barth, M; Vögtli, M1
Enenkel, B; Fussenegger, M; Meents, H; Werner, RG1
Lagace, TA; Ridgway, ND1
Braverman, R; DeClue, JE; Li, H; Li, S; Lowy, DR; Vass, WC1
Burns, E; Christensen, E; Henrich, VC; Weinberger, C; Yelverton, DP1
Detlefsen, DJ; Molitor, PF; Norcross, JA; O'Neil-Johnson, M; Olson, DL; Peck, TL; Wilson, AG1
Boros, A; Dezso, P; Fodor, L; Kolok, S; Kurkó, D; Nagy, J; Szombathelyi, Z1
Boulukos, KE; Carlotti, F; Hoeben, RC; Martin, P; Pognonec, P; Zaldumbide, A1
Claret, FX; Johnson, TJ; Korapati, AL; Mansouri, A; Tian, L; Zhang, Q1
Bösser, S; Oehme, I; Zörnig, M1
Baron, C; Borowsky, AD; Cao, Z; Cardiff, RD; Carraway, KL; Gregg, JP; Ingalla, ER; Sweeney, C; Wu, X; Yen, L; Young, LJ1
Beatty, J; Callender, JL; Fauth, T; Henrich, VC; Spindler-Barth, M1
Collado, D; Hamaguchi, M; Yoshihara, T1
Azoitei, A; Nieva, C; Spindler, KD; Spindler-Barth, M1
Hermiston, TW; Nair, A; Xie, J1
Gao, H; Gerke, P; Imgrund, M; Kramer-Zucker, AG; Nickel, C; Nitschke, R; Pütz, M; Sellin, LK; Walz, G1
Dinan, L; Lapenna, S1
Feuerbach, D; Koller, M; Loetscher, E; Neurdin, S1
Behrendt, L; Stegeman, JJ; Tarrant, AM; Verslycke, T1
Bielska, K; Kędracka-Krok, S; Niedenthal, R; Ożyhar, A; Seliga, J; Wieczorek, E1
Kearns, F; Liu, C; Mehrotra, P; Mhashilkar, AS; Palli, SR; Tzertzinis, G; Unnasch, TR; Vankayala, SL; Woodcock, HL1

Other Studies

57 other study(ies) available for muristerone a and ecdysterone

ArticleYear
Isoforms of the heteropteran Nezara viridula ecdysone receptor: protein characterisation, RH5992 insecticide binding and homology modelling.
    Pest management science, 2011, Volume: 67, Issue:11

    Topics: Amino Acid Sequence; Animals; Ecdysteroids; Ecdysterone; Electrophoresis, Gel, Two-Dimensional; Heteroptera; Hydrazines; Insecticides; Ligands; Mass Spectrometry; Molecular Sequence Data; Protein Binding; Protein Isoforms; Receptors, Steroid; Sequence Analysis, Protein

2011
Significant activity of ecdysteroids on the resistance to doxorubicin in mammalian cancer cells expressing the human ABCB1 transporter.
    Journal of medicinal chemistry, 2012, Jun-14, Volume: 55, Issue:11

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Doxorubicin; Drug Antagonism; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Ecdysteroids; Humans; Mice; Structure-Activity Relationship

2012
Characterization and partial purification of the Drosophila Kc cell ecdysteroid receptor.
    The Journal of biological chemistry, 1988, Apr-05, Volume: 263, Issue:10

    Topics: Animals; Cell Line; Drosophila melanogaster; Ecdysterone; Kinetics; Molecular Weight; Receptors, Steroid

1988
Identification and characterization of a Drosophila nuclear receptor with the ability to inhibit the ecdysone response.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Nov-07, Volume: 92, Issue:23

    Topics: Amino Acid Sequence; Animals; Blotting, Northern; Blotting, Southern; Drosophila; Ecdysone; Ecdysterone; Genes, Insect; Genomic Library; In Situ Hybridization; Molecular Sequence Data; Protein Binding; Receptors, Retinoic Acid; Recombinant Proteins; Retinoid X Receptors; Sequence Analysis, DNA; Signal Transduction; Time Factors; Tissue Distribution; Transcription Factors

1995
Functional ecdysone receptor is the product of EcR and Ultraspiracle genes.
    Nature, 1993, Dec-02, Volume: 366, Issue:6454

    Topics: Animals; Cell Line; Chromosomes; DNA; DNA-Binding Proteins; Drosophila; Drosophila Proteins; Ecdysone; Ecdysterone; Genes, Insect; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Receptors, Steroid; Retinoid X Receptors; Transcription Factors

1993
Heterodimerization of the Drosophila ecdysone receptor with retinoid X receptor and ultraspiracle.
    Nature, 1993, Apr-01, Volume: 362, Issue:6419

    Topics: Animals; Base Sequence; Cell Line; DNA; DNA-Binding Proteins; Drosophila; Ecdysone; Ecdysterone; HeLa Cells; Humans; Macromolecular Substances; Molecular Sequence Data; Oligodeoxyribonucleotides; Protein Biosynthesis; Receptors, Cell Surface; Receptors, Retinoic Acid; Receptors, Steroid; Retinoid X Receptors; Retinoids; Transcription Factors; Transfection; Tretinoin

1993
Ecdysone-inducible gene expression in mammalian cells and transgenic mice.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Apr-16, Volume: 93, Issue:8

    Topics: Animals; Base Sequence; Biological Availability; Cell Line; Drosophila melanogaster; Ecdysone; Ecdysterone; Gene Expression; Mice; Mice, Transgenic; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Promoter Regions, Genetic; Receptors, Steroid; Tetracycline; Transfection

1996
The overexpression of Bax produces cell death upon induction of the mitochondrial permeability transition.
    The Journal of biological chemistry, 1998, Mar-27, Volume: 273, Issue:13

    Topics: Apoptosis; Aristolochic Acids; bcl-2-Associated X Protein; Caspase 3; Caspases; Cyclosporine; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytochrome c Group; Cytosol; DNA Fragmentation; Ecdysterone; Enzyme Activation; Humans; Intracellular Membranes; Jurkat Cells; Mitochondria; Oligopeptides; Permeability; Phenanthrenes; Phospholipases A; Phospholipases A2; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Transfection

1998
High level transactivation by the ecdysone receptor complex at the core recognition motif.
    Nucleic acids research, 1998, May-15, Volume: 26, Issue:10

    Topics: Animals; Base Sequence; Binding Sites; Cell Line; Dimerization; DNA; DNA-Binding Proteins; Drosophila melanogaster; Drosophila Proteins; Ecdysterone; Ligands; Receptors, Steroid; Recombinant Fusion Proteins; Transcription Factors; Transcriptional Activation; Transfection

1998
Differential stimulation of cholesterol and unsaturated fatty acid biosynthesis in cells expressing individual nuclear sterol regulatory element-binding proteins.
    The Journal of biological chemistry, 1998, Oct-02, Volume: 273, Issue:40

    Topics: Animals; CCAAT-Enhancer-Binding Proteins; CHO Cells; Cholesterol; Cricetinae; DNA-Binding Proteins; Ecdysterone; Farnesyl-Diphosphate Farnesyltransferase; Fatty Acids, Unsaturated; Gene Expression Regulation; Hydroxymethylglutaryl CoA Reductases; Nuclear Proteins; Promoter Regions, Genetic; Receptors, LDL; RNA, Messenger; Stearoyl-CoA Desaturase; Sterol Regulatory Element Binding Protein 1; Sterol Regulatory Element Binding Protein 2; Transcription Factors; Transcriptional Activation

1998
Inhibition of growth and proliferation of EcRG293 cell line expressing high-affinity gonadotropin-releasing hormone (GnRH) receptor under the control of an inducible promoter by GnRH agonist (D-Lys6)GnRH and antagonist (Antide).
    Cancer research, 1998, Oct-15, Volume: 58, Issue:20

    Topics: Cell Division; Cell Line; Ecdysterone; Gonadotropin-Releasing Hormone; Hormone Antagonists; Humans; Oligopeptides; Receptors, LHRH

1998
Cell-specific ecdysone-inducible expression of FLP recombinase in mammalian cells.
    BioTechniques, 1998, Volume: 25, Issue:5

    Topics: 3T3 Cells; Animals; beta-Galactosidase; Cloning, Molecular; DNA Nucleotidyltransferases; Ecdysone; Ecdysterone; Gene Expression Regulation; Lac Operon; Mice; Plasmids; Promoter Regions, Genetic; Recombinant Fusion Proteins; Recombination, Genetic; Transfection

1998
Inducible expression of erythrocyte band 3 protein.
    The American journal of physiology, 1999, Volume: 276, Issue:1

    Topics: Anion Exchange Protein 1, Erythrocyte; Biological Transport; Blotting, Western; Cell Line; Chlorides; Ecdysterone; Fluorescent Antibody Technique; Humans; Stilbenes

1999
Inducible genetic suppression of neuronal excitability.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Mar-01, Volume: 19, Issue:5

    Topics: Action Potentials; Adenoviridae; Animals; Animals, Newborn; Barium; Cells, Cultured; Ecdysone; Ecdysterone; Gene Expression Regulation; Genes, Reporter; Humans; Immunohistochemistry; In Vitro Techniques; Microtubule-Associated Proteins; Neurons; Patch-Clamp Techniques; Potassium; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Transfection

1999
Impairment of the proapoptotic activity of Bax by missense mutations found in gastrointestinal cancers.
    Cancer research, 1999, May-01, Volume: 59, Issue:9

    Topics: Alanine; Amino Acid Substitution; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Biological Transport; Cell Line, Transformed; Codon; Dimerization; DNA Mutational Analysis; Ecdysterone; Frameshift Mutation; Gastrointestinal Neoplasms; Humans; Kidney; Methionine; Microsatellite Repeats; Mutation, Missense; Neoplasm Proteins; Protein Binding; Protein Multimerization; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Receptors, Retinoic Acid; Receptors, Steroid; Recombinant Fusion Proteins; Retinoid X Receptors; Threonine; Transcription Factors; Transfection

1999
Creation of ecdysone receptor chimeras in plants for controlled regulation of gene expression.
    Molecular & general genetics : MGG, 1999, Volume: 261, Issue:3

    Topics: Chimera; Drosophila; Ecdysone; Ecdysterone; Gene Expression Regulation, Plant; Genes, Insect; Genes, Plant; Genes, Reporter; Herpes Simplex Virus Protein Vmw65; Lepidoptera; Molecular Sequence Data; Receptors, Glucocorticoid; Receptors, Steroid; Simplexvirus; Transcriptional Activation; Transformation, Genetic; Zea mays

1999
The interferon-inducible nucleolar p204 protein binds the ribosomal RNA-specific UBF1 transcription factor and inhibits ribosomal RNA transcription.
    The EMBO journal, 1999, May-17, Volume: 18, Issue:10

    Topics: Animals; Cell Division; Cell Nucleolus; DNA Footprinting; DNA-Binding Proteins; Ecdysterone; Gene Expression Regulation; Interferons; Mice; Nuclear Proteins; Pol1 Transcription Initiation Complex Proteins; Promoter Regions, Genetic; Protein Binding; Regulatory Sequences, Nucleic Acid; RNA, Ribosomal; Transcription Factors; Transcription, Genetic

1999
Induced p21waf expression in H1299 cell line promotes cell senescence and protects against cytotoxic effect of radiation and doxorubicin.
    Oncogene, 1999, Apr-22, Volume: 18, Issue:16

    Topics: Adenocarcinoma; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; Doxorubicin; Drug Resistance; Ecdysterone; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Radiation Tolerance; Tumor Cells, Cultured

1999
Exogenous expression of p16INK4a is associated with decrease in telomerase activity.
    Journal of neuro-oncology, 1999, Volume: 42, Issue:1

    Topics: Brain Neoplasms; Cell Cycle; Cell Division; Clone Cells; Cyclin-Dependent Kinase Inhibitor p16; Ecdysterone; Gene Expression Regulation; Glioblastoma; Humans; Microscopy, Electron, Scanning; Plasmids; Recombinant Proteins; Telomerase; Transfection; Tumor Cells, Cultured

1999
EcR interacts with corepressors and harbours an autonomous silencing domain functional in both Drosophila and vertebrate cells.
    The Journal of steroid biochemistry and molecular biology, 1999, Volume: 68, Issue:3-4

    Topics: Animals; Cell Line; Chlorocebus aethiops; DNA-Binding Proteins; Drosophila melanogaster; Ecdysterone; Fungal Proteins; Gene Expression Regulation; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Recombinant Fusion Proteins; Recombinant Proteins; Repressor Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transcription Factors; Transfection

1999
Virus-mediated modification of cellular excitability.
    Annals of the New York Academy of Sciences, 1999, Apr-30, Volume: 868

    Topics: Action Potentials; Adenoviridae; Animals; Barium; Cation Transport Proteins; Cells, Cultured; DNA-Binding Proteins; Ecdysterone; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Genetic Vectors; Heart Ventricles; Humans; Long QT Syndrome; Mutation; Neurons; Potassium Channels; Potassium Channels, Inwardly Rectifying; Potassium Channels, Voltage-Gated; Rabbits; Superior Cervical Ganglion; Trans-Activators; Transcriptional Regulator ERG

1999
Transcriptional activation of the cloned Heliothis virescens (Lepidoptera) ecdysone receptor (HvEcR) by muristeroneA.
    Insect biochemistry and molecular biology, 1999, Volume: 29, Issue:10

    Topics: Amino Acid Sequence; Animals; ATP-Binding Cassette Transporters; Base Sequence; DNA, Complementary; Ecdysterone; Fungal Proteins; Molecular Sequence Data; Moths; Neoplasm Proteins; Receptors, Steroid; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Transcriptional Activation

1999
Induction of human high K(M) 5'-nucleotidase in cultured 293 cells.
    Experimental cell research, 1999, Dec-15, Volume: 253, Issue:2

    Topics: 5'-Nucleotidase; Adenosine Triphosphate; Antineoplastic Agents; Blotting, Western; Cells, Cultured; Cladribine; Cloning, Molecular; Cytidine Triphosphate; DNA, Complementary; Ecdysterone; Enzyme Activation; Gene Expression Regulation, Enzymologic; Genes, Reporter; Green Fluorescent Proteins; Guanosine Triphosphate; Humans; Indicators and Reagents; Kidney; Luminescent Proteins; Plasmids; Receptors, Steroid; Transfection; Uridine Triphosphate

1999
Basal signaling activity of human dopamine D2L receptor demonstrated with an ecdysone-inducible mammalian expression system.
    Journal of neuroscience methods, 2000, Jan-15, Volume: 94, Issue:2

    Topics: Cell Line; Dose-Response Relationship, Drug; Ecdysone; Ecdysterone; Humans; Receptors, Dopamine D2; Signal Transduction

2000
Steroid- and retinoid-mediated growth arrest and apoptosis in WEHI-231 cells: role of NF-kappaB, c-Myc and CKI p27(Kip1).
    European journal of immunology, 2000, Volume: 30, Issue:4

    Topics: Amino Acid Chloromethyl Ketones; Animals; Antibodies, Anti-Idiotypic; Apoptosis; B-Lymphocytes; Caspase Inhibitors; Caspases; CD40 Ligand; Cell Cycle Proteins; Cell Division; Cyclin-Dependent Kinase Inhibitor p27; Dexamethasone; Down-Regulation; Ecdysterone; G1 Phase; Immunoglobulin M; Membrane Glycoproteins; Mice; Microtubule-Associated Proteins; NF-kappa B; Proto-Oncogene Proteins c-myc; Receptor Aggregation; Retinoids; Signal Transduction; Steroids; Tumor Cells, Cultured; Tumor Suppressor Proteins; Up-Regulation

2000
Nitric oxide upregulates expression of DNA-PKcs to protect cells from DNA-damaging anti-tumour agents.
    Nature cell biology, 2000, Volume: 2, Issue:6

    Topics: Animals; Antineoplastic Agents; Bleomycin; Catalytic Domain; Cell Line; Cell Survival; Cisplatin; DNA; DNA Damage; DNA Repair; DNA-Activated Protein Kinase; DNA-Binding Proteins; Doxorubicin; Ecdysterone; Enzyme Induction; Humans; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nuclear Proteins; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; RNA, Messenger; Sp1 Transcription Factor; Up-Regulation

2000
Reporter-linked monitoring of transgene expression in living cells using the ecdysone-inducible promoter system.
    European journal of cell biology, 2000, Volume: 79, Issue:9

    Topics: Animals; CHO Cells; Cricetinae; Ecdysone; Ecdysterone; Gene Expression Regulation; Genes, Reporter; Green Fluorescent Proteins; Indicators and Reagents; Luminescent Proteins; Molecular Biology; Promoter Regions, Genetic; RNA, Messenger; Transfection; Transgenes

2000
Identification of ligands and coligands for the ecdysone-regulated gene switch.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Dec-19, Volume: 97, Issue:26

    Topics: Animals; Cholestenes; Ecdysone; Ecdysteroids; Ecdysterone; Gene Expression Regulation; Humans; Ligands; Mice; Mice, Transgenic; Molecular Structure; Receptors, Retinoic Acid; Receptors, Steroid; Retinoid X Receptors; Steroids; Transcription Factors

2000
Plasma hyaluronidase (Hyal-1) promotes tumor cell cycling.
    Cancer letters, 2001, Feb-10, Volume: 163, Issue:1

    Topics: Cell Cycle; Dose-Response Relationship, Drug; Ecdysterone; Enzyme-Linked Immunosorbent Assay; G1 Phase; Gene Expression Regulation, Enzymologic; Humans; Hyaluronic Acid; Hyaluronoglucosaminidase; Plasmids; Recombinant Fusion Proteins; Response Elements; Resting Phase, Cell Cycle; S Phase; Substrate Specificity; Transfection; Tumor Cells, Cultured

2001
Life and death decisions in B1 lymphoma cells.
    Current topics in microbiology and immunology, 2000, Volume: 252

    Topics: Antibodies, Anti-Idiotypic; Apoptosis; B-Lymphocyte Subsets; Caspases; CD40 Antigens; CD40 Ligand; Cell Cycle; Cell Cycle Proteins; Cell Survival; Cyclin-Dependent Kinase Inhibitor p27; Dexamethasone; Ecdysterone; Enzyme Activation; Enzyme Induction; Enzyme Precursors; G1 Phase; Gene Expression Regulation, Neoplastic; Genes, myc; Humans; Intracellular Signaling Peptides and Proteins; Lymphoma, B-Cell; Microtubule-Associated Proteins; Neoplasm Proteins; Neoplastic Stem Cells; Phosphatidylinositol 3-Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-myc; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Retinoid X Receptors; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Syk Kinase; Transcription Factors; Transfection; Tretinoin; Tumor Suppressor Proteins

2000
Ectopic expression of cyclin D1 impairs the proliferation and enhances the apoptosis of a murine lymphoid cell line.
    Cell death and differentiation, 2001, Volume: 8, Issue:1

    Topics: Animals; Apoptosis; B-Lymphocytes; bcl-2-Associated X Protein; Cell Cycle; Cell Cycle Proteins; Cell Division; Cell Line; Cell Survival; Clone Cells; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dose-Response Relationship, Drug; Ecdysterone; Etoposide; Genetic Vectors; Interleukin-3; Mice; Nucleic Acid Synthesis Inhibitors; Promoter Regions, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Stem Cells; Transfection; Tumor Suppressor Protein p53

2001
Muristerone A-induced nerve growth factor release from genetically engineered human dermal fibroblasts for peripheral nerve tissue engineering.
    Tissue engineering, 2001, Volume: 7, Issue:3

    Topics: Animals; Biocompatible Materials; Cell Differentiation; Cell Line; Diffusion Chambers, Culture; Ecdysterone; Fibroblasts; Genetic Engineering; Humans; Male; Nerve Growth Factor; Peripheral Nerves; Polymerase Chain Reaction; Rats; Rats, Nude; Skin; Transfection

2001
Titrating the expression of a Gi protein-coupled receptor using an ecdysone-inducible system in CHO-K1 cells.
    Receptors & channels, 2001, Volume: 7, Issue:4

    Topics: Animals; CHO Cells; Cricetinae; Ecdysterone; Gene Expression; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Receptors, Somatostatin; Titrimetry

2001
Double-stranded RNA-dependent protein kinase, PKR, down-regulates CDC2/cyclin B1 and induces apoptosis in non-transformed but not in v-mos transformed cells.
    Oncogene, 2001, Dec-06, Volume: 20, Issue:56

    Topics: Animals; Apoptosis; CDC2 Protein Kinase; Cell Cycle; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; CHO Cells; Cricetinae; Cyclin B; Cyclin B1; Down-Regulation; Ecdysterone; eIF-2 Kinase; Flow Cytometry; Kinetics; Oncogene Proteins v-mos; Transfection; Transformation, Genetic

2001
Phenotypic changes associated with exogenous expression of p16INK4a in human glioma cells.
    Brain tumor pathology, 2001, Volume: 18, Issue:2

    Topics: Bradykinin; Brain Neoplasms; Cell Adhesion; Culture Media, Serum-Free; Cyclin-Dependent Kinase Inhibitor p16; Ecdysone; Ecdysterone; Epidermal Growth Factor; Gene Expression Regulation, Neoplastic; Genes, p16; Glioma; GTP-Binding Proteins; Humans; Insulin; Integrins; Neoplasm Proteins; Promoter Regions, Genetic; Pseudopodia; Recombinant Fusion Proteins; Signal Transduction; Tumor Cells, Cultured

2001
Low amounts of the DNA repair XPA protein are sufficient to recover UV-resistance.
    Carcinogenesis, 2002, Volume: 23, Issue:6

    Topics: Cell Line; Cell Survival; Cells, Cultured; Connexins; DNA; DNA Repair; DNA Replication; DNA-Binding Proteins; Ecdysterone; Flow Cytometry; Genetic Vectors; Genome; HeLa Cells; Humans; Kinetics; Transcription, Genetic; Transfection; Ultraviolet Rays; Xeroderma Pigmentosum; Xeroderma Pigmentosum Group A Protein

2002
Ligand-induced heterodimerization between the ligand binding domains of the Drosophila ecdysteroid receptor and ultraspiracle.
    European journal of biochemistry, 2002, Volume: 269, Issue:13

    Topics: Animals; Binding Sites; Dimerization; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drosophila; Drosophila Proteins; Ecdysteroids; Ecdysterone; Ligands; Receptors, Steroid; Recombinant Fusion Proteins; Response Elements; Transcription Factors; Two-Hybrid System Techniques; Yeasts

2002
p27Kip1-mediated controlled proliferation technology increases constitutive sICAM production in CHO-DUKX adapted for growth in suspension and serum-free media.
    Biotechnology and bioengineering, 2002, Sep-20, Volume: 79, Issue:6

    Topics: Animals; Cell Culture Techniques; Cell Cycle Proteins; Cell Division; Cell Line; CHO Cells; Cricetinae; Culture Media, Serum-Free; Cyclin-Dependent Kinase Inhibitor p27; Dose-Response Relationship, Drug; Ecdysterone; Enzyme Inhibitors; Gene Expression Regulation; Intercellular Adhesion Molecule-1; Protein Engineering; Reproducibility of Results; Sensitivity and Specificity; Suspensions; Tetrahydrofolate Dehydrogenase; Tumor Suppressor Proteins

2002
Regulation of the CDP-choline pathway by sterol regulatory element binding proteins involves transcriptional and post-transcriptional mechanisms.
    The Biochemical journal, 2003, Jun-15, Volume: 372, Issue:Pt 3

    Topics: Acyl Coenzyme A; Animals; CCAAT-Enhancer-Binding Proteins; Cerulenin; CHO Cells; Choline Kinase; Choline-Phosphate Cytidylyltransferase; Cricetinae; Cytidine Diphosphate Choline; Diglycerides; DNA-Binding Proteins; Ecdysterone; Fatty Acids; Gene Expression Regulation; Immunoblotting; Phosphatidylcholines; Protein Processing, Post-Translational; RNA, Messenger; Sterol Regulatory Element Binding Protein 1; Sterol Regulatory Element Binding Protein 2; Transcription Factors; Transcription, Genetic; Triazenes

2003
Regulation of cell morphology and adhesion by the tuberous sclerosis complex (TSC1/2) gene products in human kidney epithelial cells through increased E-cadherin/beta-catenin activity.
    Molecular carcinogenesis, 2003, Volume: 37, Issue:2

    Topics: Animals; beta Catenin; Cadherins; Calcium; Cell Adhesion; Cell Division; Cells, Cultured; Clone Cells; Cytoskeletal Proteins; Ecdysterone; Epithelial Cells; Fibroblasts; Gene Expression Regulation; Humans; Kidney; Proteins; Rats; Repressor Proteins; Trans-Activators; Tuberous Sclerosis Complex 1 Protein; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins

2003
Juvenile hormone potentiates ecdysone receptor-dependent transcription in a mammalian cell culture system.
    Insect biochemistry and molecular biology, 2003, Volume: 33, Issue:12

    Topics: Animals; CHO Cells; Cricetinae; Drosophila; Ecdysterone; Genes, Reporter; Ligands; Luciferases; Mice; Protein Isoforms; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Recombinant Proteins; Sesquiterpenes; Transcription, Genetic; Transfection

2003
Microflow NMR: concepts and capabilities.
    Analytical chemistry, 2004, May-15, Volume: 76, Issue:10

    Topics: Automation; Carbon; Chromatography, High Pressure Liquid; Ecdysterone; Microchemistry; Nuclear Magnetic Resonance, Biomolecular; Protons; Sensitivity and Specificity; Solvents; Sucrose

2004
Inducible expression and pharmacological characterization of recombinant rat NR1a/NR2A NMDA receptors.
    Neurochemistry international, 2005, Volume: 46, Issue:5

    Topics: Animals; Calcium; Calcium Signaling; Cell Line; Cloning, Molecular; Dose-Response Relationship, Drug; Ecdysterone; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Genetic Vectors; Humans; Ion Channels; Membrane Potentials; N-Methylaspartate; Patch-Clamp Techniques; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Transfection; Up-Regulation

2005
Development of an inducible suicide gene system based on human caspase 8.
    Cancer gene therapy, 2005, Volume: 12, Issue:7

    Topics: Animals; Apoptosis; Breast Neoplasms; Caspase 8; Caspases; Cell Line; Dimerization; Ecdysterone; Gene Expression Regulation; Genes, Transgenic, Suicide; Genetic Therapy; Genetic Vectors; Humans; Lentivirus; Mice; Plasmids; Retroviridae; Tetracycline; Transfection

2005
Inducible expression of a degradation-resistant form of p27Kip1 causes growth arrest and apoptosis in breast cancer cells.
    FEBS letters, 2005, Jul-18, Volume: 579, Issue:18

    Topics: Adenoviridae; Alanine; Annexin A5; Apoptosis; Biomarkers, Tumor; Breast Neoplasms; CDC2-CDC28 Kinases; Cell Cycle; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p27; Doxycycline; Ecdysterone; Humans; Immunoblotting; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Prognosis; Proteasome Endopeptidase Complex; Proteins; S Phase; Threonine; Time Factors; Tumor Suppressor Proteins; Ubiquitin

2005
Agonists of an ecdysone-inducible mammalian expression system inhibit Fas Ligand- and TRAIL-induced apoptosis in the human colon carcinoma cell line RKO.
    Cell death and differentiation, 2006, Volume: 13, Issue:2

    Topics: Androstadienes; Apoptosis; Apoptosis Regulatory Proteins; bcl-X Protein; Caspase 8; Caspases; Cell Cycle; Cell Line, Tumor; Chromones; Colonic Neoplasms; Ecdysterone; Enzyme Activation; Fas Ligand Protein; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; Membrane Glycoproteins; Morpholines; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Proliferating Cell Nuclear Antigen; Protein Kinase C; Recombinant Proteins; RNA, Messenger; Signal Transduction; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha; Tumor Necrosis Factors; Wortmannin

2006
Loss of Nrdp1 enhances ErbB2/ErbB3-dependent breast tumor cell growth.
    Cancer research, 2006, Dec-01, Volume: 66, Issue:23

    Topics: Animals; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Ecdysterone; Extracellular Signal-Regulated MAP Kinases; Female; Genetic Vectors; Humans; Mammary Neoplasms, Animal; Mice; Mice, Transgenic; Nerve Tissue Proteins; Neuregulin-1; Phosphatidylinositol 3-Kinases; Receptor, ErbB-2; Receptor, ErbB-3; Retroviridae; RNA, Small Interfering; Signal Transduction; Transfection; Ubiquitin-Protein Ligases

2006
Analysis of transcriptional activity mediated by Drosophila melanogaster ecdysone receptor isoforms in a heterologous cell culture system.
    Insect molecular biology, 2006, Volume: 15, Issue:6

    Topics: Animals; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; DNA-Binding Proteins; Drosophila melanogaster; Drosophila Proteins; Ecdysterone; Electrophoretic Mobility Shift Assay; Immunoblotting; Insect Proteins; Mutagenesis, Site-Directed; Mutation; Protein Isoforms; Receptors, Steroid; Response Elements; Transcription Factors; Transcription, Genetic; Transfection

2006
DBC2 resistance is achieved by enhancing 26S proteasome-mediated protein degradation.
    Biochemical and biophysical research communications, 2007, Aug-31, Volume: 360, Issue:3

    Topics: Blotting, Western; Breast Neoplasms; Cell Line; Cysteine Proteinase Inhibitors; Drug Resistance, Neoplasm; Ecdysterone; Female; Gene Expression Regulation, Neoplastic; Gene Transfer Techniques; GTP-Binding Proteins; Humans; Leupeptins; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Transgenes; Tumor Suppressor Proteins

2007
Influence of hormone on intracellular localization of the Drosophila melanogaster ecdysteroid receptor (EcR).
    Cellular signalling, 2007, Volume: 19, Issue:12

    Topics: Active Transport, Cell Nucleus; Animals; Cell Nucleus; Chlorocebus aethiops; CHO Cells; COS Cells; Cricetinae; Cricetulus; Cytoplasm; Dimerization; DNA; DNA-Binding Proteins; Drosophila Proteins; Ecdysterone; Ligands; Mutation; Protein Structure, Tertiary; Receptors, Steroid; Time Factors; Transcription Factors; Transcriptional Activation; Transfection

2007
A comparative study examining the cytotoxicity of inducible gene expression system ligands in different cell types.
    Toxicology in vitro : an international journal published in association with BIBRA, 2008, Volume: 22, Issue:1

    Topics: Cell Death; Cell Line; Cell Line, Tumor; Dose-Response Relationship, Drug; Doxycycline; Drug Delivery Systems; Ecdysterone; Gene Expression Profiling; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Humans; Ligands; Mifepristone

2008
A short carboxy-terminal domain of polycystin-1 reorganizes the microtubular network and the endoplasmic reticulum.
    Experimental cell research, 2009, Apr-15, Volume: 315, Issue:7

    Topics: Amino Acid Sequence; Animals; Cell Line; Cytoskeletal Proteins; Ecdysterone; Endoplasmic Reticulum; Humans; Membrane Proteins; Mice; Microtubules; Molecular Sequence Data; Polycystic Kidney, Autosomal Dominant; Protein Structure, Tertiary; Sequence Alignment; TRPP Cation Channels

2009
HPLC and TLC characterisation of ecdysteroid alkyl ethers.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009, Oct-01, Volume: 877, Issue:27

    Topics: Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Ecdysteroids; Ecdysterone

2009
Comparative pharmacology of the human NMDA-receptor subtypes R1-2A, R1-2B, R1-2C and R1-2D using an inducible expression system.
    European journal of pharmacology, 2010, Jul-10, Volume: 637, Issue:1-3

    Topics: Base Sequence; Calcium; Calcium Signaling; Cells, Cultured; Cloning, Molecular; Ecdysterone; Fluorometry; Gene Expression; Humans; Protein Subunits; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction

2010
Ecdysteroid receptor from the American lobster Homarus americanus: EcR/RXR isoform cloning and ligand-binding properties.
    General and comparative endocrinology, 2011, Sep-01, Volume: 173, Issue:2

    Topics: Animals; Ecdysterone; Hydrazines; Nephropidae; Phthalic Acids; Polychlorinated Biphenyls; Protein Isoforms; Receptors, Steroid

2011
Alternative sumoylation sites in the Drosophila nuclear receptor Usp.
    The Journal of steroid biochemistry and molecular biology, 2012, Volume: 132, Issue:3-5

    Topics: Animals; Cell Line; DNA-Binding Proteins; Drosophila melanogaster; Drosophila Proteins; Ecdysterone; Humans; Ligands; Lysine; Receptors, Steroid; Recombinant Fusion Proteins; Sumoylation; Transcription Factors; Ubiquitin-Conjugating Enzymes

2012
Identification of Ecdysone Hormone Receptor Agonists as a Therapeutic Approach for Treating Filarial Infections.
    PLoS neglected tropical diseases, 2016, Volume: 10, Issue:6

    Topics: Amino Acids, Diamino; Animals; Brugia malayi; Drug Discovery; Drug Evaluation, Preclinical; Ecdysone; Ecdysterone; Filariasis; Gerbillinae; HEK293 Cells; Humans; Hydrazines; Larva; Ligands; Models, Molecular; Molecular Docking Simulation; Receptors, Steroid

2016