Page last updated: 2024-09-03

muricholic acid and ursodeoxycholic acid

muricholic acid has been researched along with ursodeoxycholic acid in 18 studies

Compound Research Comparison

Studies
(muricholic acid)
Trials
(muricholic acid)
Recent Studies (post-2010)
(muricholic acid)
Studies
(ursodeoxycholic acid)
Trials
(ursodeoxycholic acid)
Recent Studies (post-2010) (ursodeoxycholic acid)
1191364,5926261,561

Protein Interaction Comparison

ProteinTaxonomymuricholic acid (IC50)ursodeoxycholic acid (IC50)
Bile salt export pumpHomo sapiens (human)10
Sodium/bile acid cotransporterHomo sapiens (human)3.6
M1-family alanyl aminopeptidasePlasmodium falciparum 3D72.6

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19904 (22.22)18.7374
1990's8 (44.44)18.2507
2000's2 (11.11)29.6817
2010's3 (16.67)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Ban, Y; Kuriyama, K; Murata, T; Nakashima, T1
Minagawa, K; Sano, N; Takikawa, H; Yamanaka, M1
Kanai, S; Kitani, K; Sato, Y1
Angellotti, MA; Fini, A; Minutello, A; Roda, A1
Classen, M; Dikimli, A; Kurtz, WJ; Leuschner, U1
Amic, J; Infante, R; Montet, AM; Montet, JC; Parquet, M; Sacquet, E1
Cohen, BI; Finver-Sadowsky, J; McSherry, CK; Mosbach, EH; Singhal, AK1
Kren, BT; O'Connell, NC; Rodrigues, CM; Setchell, KD; Steer, CJ; Yamashita, H1
Kren, BT; Rodrigues, CM; Setchell, KD; Steer, CJ1
Cohen-Solal, C; Dupré, J; Lamcharfi, E; Lutton, C; Meyer, C; Parquet, M1
Alberts, D; Batta, AK; Brasitus, TA; Earnest, DL; Holubec, H; Salen, G1
Inaba, K; Ishikawa, H; Kashima, K; Mitsuyoshi, H; Nakajima, Y; Nakashima, T; Sakai, M; Sakamoto, Y; Shima, T1
Marschall, HU; Matern, S; Purucker, E; Winograd, R1
Kakisaka, Y; Mitsuyoshi, H; Nakashima, T; Sumida, Y; Yoh, T1
Poša, M1
Fujita, K; Iguchi, Y; Une, M; Watanabe, S1
Aguesse, A; Boursier, J; Chaigneau, J; Coué, M; Croyal, M; Falewée, J; Fizanne, L; Ouguerram, K; Tesse, A1
Bloks, VW; de Boer, JF; de Vries, HD; Doestzada, M; Dombrowicz, D; Fu, J; Haas, JT; Hoogerland, JA; Hovingh, MV; Kloosterhuis, NJ; Koehorst, M; Kuipers, F; La Rose, AM; Li, R; Mulder, NL; Palmiotti, A; Staels, B; van de Sluis, B; Westerterp, M; Wolters, JC1

Trials

1 trial(s) available for muricholic acid and ursodeoxycholic acid

ArticleYear
A paucity of unusual trihydroxy bile acids in the urine of patients with severe liver diseases.
    Hepatology (Baltimore, Md.), 1999, Volume: 29, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Aged; Cholagogues and Choleretics; Cholic Acids; Female; Hepatitis; Humans; Liver Cirrhosis; Male; Middle Aged; Reference Values; Severity of Illness Index; Ursodeoxycholic Acid

1999

Other Studies

17 other study(ies) available for muricholic acid and ursodeoxycholic acid

ArticleYear
Simultaneous determination of biliary cile acids in rat: electron impact and ammonia chemical ionization mass spectrometric analyses of bile acids.
    Steroids, 1979, Volume: 34, Issue:6 Spec no

    Topics: Animals; Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acids; Deoxycholic Acid; Gas Chromatography-Mass Spectrometry; Lithocholic Acid; Male; Mass Spectrometry; Rats; Ursodeoxycholic Acid

1979
Effects of ursodeoxycholate, its glucuronide and disulfate and beta-muricholate on biliary bicarbonate concentration and biliary lipid excretion.
    Journal of hepatology, 1992, Volume: 15, Issue:1-2

    Topics: Animals; Bicarbonates; Bile Acids and Salts; Cholesterol; Cholic Acids; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Infusions, Intravenous; Lipid Metabolism; Lipids; Male; Rats; Rats, Inbred Strains; Ursodeoxycholic Acid

1992
Bile secretory characteristics of beta-muricholate and its taurine conjugate are similar to those of ursodeoxycholate in the rat.
    Life sciences, 1991, Volume: 48, Issue:10

    Topics: Animals; Bicarbonates; Bile; Bile Acids and Salts; Cholagogues and Choleretics; Cholic Acids; Male; Rats; Rats, Inbred Strains; Taurocholic Acid; Ursodeoxycholic Acid

1991
Bile acid structure-activity relationship: evaluation of bile acid lipophilicity using 1-octanol/water partition coefficient and reverse phase HPLC.
    Journal of lipid research, 1990, Volume: 31, Issue:8

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acid; Cholic Acids; Chromatography, High Pressure Liquid; Deoxycholic Acid; Hydrogen-Ion Concentration; Lipids; Octanols; Structure-Activity Relationship; Ursodeoxycholic Acid

1990
Antral mucosal bile acids in two types of chronic atrophic gastritis.
    The Tokai journal of experimental and clinical medicine, 1988, Volume: 13, Issue:1

    Topics: Adult; Aged; Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acid; Cholic Acids; Deoxycholic Acid; Female; Gastric Mucosa; Gastritis; Gastritis, Atrophic; Humans; Intestines; Lithocholic Acid; Male; Metaplasia; Middle Aged; Pyloric Antrum; Stomach Neoplasms; Ursodeoxycholic Acid

1988
beta-Muricholic acid; potentiometric and cholesterol-dissolving properties.
    Biochimica et biophysica acta, 1987, Mar-13, Volume: 918, Issue:1

    Topics: Animals; Chemical Phenomena; Chemistry, Physical; Chenodeoxycholic Acid; Cholesterol; Cholic Acids; Hydrogen-Ion Concentration; Mass Spectrometry; Mathematics; Micelles; Potentiometry; Rats; Solubility; Ursodeoxycholic Acid

1987
Role of hydrophilic bile acids and of sterols on cholelithiasis in the hamster.
    Journal of lipid research, 1984, Volume: 25, Issue:6

    Topics: Animals; Bile; Bile Acids and Salts; Cholanes; Cholelithiasis; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Cholic Acids; Cricetinae; Deoxycholic Acid; Diet; Hydroxymethylglutaryl CoA Reductases; Liver; Male; Mesocricetus; Phospholipids; Sitosterols; Sterols; Ursodeoxycholic Acid

1984
delta 22-Ursodeoxycholic acid, a unique metabolite of administered ursodeoxycholic acid in rats, indicating partial beta-oxidation as a major pathway for bile acid metabolism.
    Biochemistry, 1995, Apr-04, Volume: 34, Issue:13

    Topics: Animals; Bile; Bile Acids and Salts; Cholic Acids; Colon; Gas Chromatography-Mass Spectrometry; Jejunum; Liver; Male; Mass Spectrometry; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Tissue Distribution; Ursodeoxycholic Acid

1995
Formation of delta 22-bile acids in rats is not gender specific and occurs in the peroxisome.
    Journal of lipid research, 1996, Volume: 37, Issue:3

    Topics: Animals; Bile Acids and Salts; Cholic Acids; Chromatography, Gas; Clofibrate; Diet; Female; Gas Chromatography-Mass Spectrometry; Hypolipidemic Agents; Intestinal Mucosa; Liver; Male; Microbodies; Rats; Rats, Sprague-Dawley; Sex Characteristics; Ursodeoxycholic Acid

1996
Determination of molecular associations of some hydrophobic and hydrophilic bile acids by infrared and Raman spectroscopy.
    European biophysics journal : EBJ, 1997, Volume: 25, Issue:4

    Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acid; Cholic Acids; Deoxycholic Acid; Lithocholic Acid; Mammals; Models, Molecular; Molecular Conformation; Solvents; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Structure-Activity Relationship; Ursodeoxycholic Acid

1997
Enrichment of the more hydrophilic bile acid ursodeoxycholic acid in the fecal water-soluble fraction after feeding to rats with colon polyps.
    Cancer research, 1998, Apr-15, Volume: 58, Issue:8

    Topics: Animals; Azoxymethane; Bile Acids and Salts; Cholic Acid; Cholic Acids; Colonic Polyps; Deoxycholic Acid; Feces; Lithocholic Acid; Male; Rats; Rats, Inbred F344; Retrospective Studies; Ursodeoxycholic Acid

1998
Metabolism and effects on cholestasis of isoursodeoxycholic and ursodeoxycholic acids in bile duct ligated rats.
    Biochimica et biophysica acta, 2001, Apr-03, Volume: 1526, Issue:1

    Topics: Animals; Bile; Bile Acids and Salts; Bile Ducts; Body Weight; Cholestasis; Cholic Acids; Eating; Ligation; Liver; Liver Function Tests; Male; Rats; Rats, Sprague-Dawley; Ursodeoxycholic Acid

2001
Differences in the efficacy of ursodeoxycholic acid and bile acid metabolism between viral liver diseases and primary biliary cirrhosis.
    Journal of gastroenterology and hepatology, 2001, Volume: 16, Issue:5

    Topics: Adult; Aged; Aspartate Aminotransferases; Bile Acids and Salts; Cholic Acids; Female; gamma-Glutamyltransferase; Hepatitis C, Chronic; Humans; Liver Cirrhosis; Liver Cirrhosis, Biliary; Liver Function Tests; Male; Middle Aged; Ursodeoxycholic Acid

2001
Heuman indices of hydrophobicity of bile acids and their comparison with a newly developed and conventional molecular descriptors.
    Biochimie, 2014, Volume: 97

    Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acid; Cholic Acids; Chromatography, Reverse-Phase; Deoxycholic Acid; Humans; Hydrophobic and Hydrophilic Interactions; Molecular Conformation; Principal Component Analysis; Regression Analysis; Ursodeoxycholic Acid

2014
Ursodeoxycholic Acid Suppresses Lipogenesis in Mouse Liver: Possible Role of the Decrease in β-Muricholic Acid, a Farnesoid X Receptor Antagonist.
    Lipids, 2017, Volume: 52, Issue:4

    Topics: Animals; Cell Line; Chenodeoxycholic Acid; Cholic Acids; Deoxycholic Acid; Gene Expression Regulation; Lipogenesis; Liver; Male; Mice; Receptors, Cytoplasmic and Nuclear; Sterol Regulatory Element Binding Protein 1; Ursodeoxycholic Acid

2017
Spirulina Liquid Extract Protects against Fibrosis Related to Non-Alcoholic Steatohepatitis and Increases Ursodeoxycholic Acid.
    Nutrients, 2019, Jan-18, Volume: 11, Issue:1

    Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Antioxidants; Blood Glucose; Cholesterol; Cholic Acids; Diet, Western; Dietary Supplements; Fibrosis; Gallbladder; Hypolipidemic Agents; Liver; Liver Cirrhosis; Male; Mice, Inbred C57BL; NF-kappa B; Nitric Oxide; Non-alcoholic Fatty Liver Disease; Spirulina; Superoxides; Thiobarbituric Acid Reactive Substances; Ursodeoxycholic Acid

2019
Cholangiopathy and Biliary Fibrosis in Cyp2c70-Deficient Mice Are Fully Reversed by Ursodeoxycholic Acid.
    Cellular and molecular gastroenterology and hepatology, 2021, Volume: 11, Issue:4

    Topics: Animals; Bile Acids and Salts; Biliary Tract Diseases; Cholangitis; Cholic Acids; Cytochrome P-450 Enzyme System; Female; Fibrosis; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Ursodeoxycholic Acid

2021