muramidase has been researched along with piriprost* in 2 studies
2 other study(ies) available for muramidase and piriprost
| Article | Year |
|---|---|
A possible requirement for arachidonic acid lipoxygenation in the mechanism of phagocytic degranulation by human neutrophils stimulated with aggregated immunoglobulin G.
Aggregated immunoglobulin G (AggIgG) caused a concentration-dependent extracellular release of granule-associated lysozyme and myeloperoxidase (MPO) from human neutrophils. Generation of the 5-lipoxygenase product of arachidonic acid (AA) metabolism, 5(S),12(R)-dihydroxy-6,14-cis,8,10-trans-eicosatetraenoic acid [leukotriene B4 (LTB4)], by neutrophils is exposed to AggIgG occurred in the presence but not absence of exogenous AA. U-60,257B (piriprost potassium), an inhibitor of leukotriene synthesis, caused a dose-related suppression of LTB4 production and granule exocytosis by AggIgG-treated cells. These data suggest that a lipoxygenase product of AA metabolism may mediate AggIgG-induced phagocytic release of granule constituents from neutrophils. Topics: Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Cytoplasmic Granules; Dose-Response Relationship, Drug; Epoprostenol; Humans; Immunoglobulin G; Leukotriene B4; Lipoxygenase; Muramidase; Neutrophils; Peroxidase; Phagocytosis | 1986 |
Effect of 6,9-deepoxy-6,9-(phenylimino)-delta 6,8-prostaglandin 1(1) (U-60,257), an inhibitor of leukotriene synthesis, on human neutrophil function.
Topics: Calcimycin; Chemotaxis, Leukocyte; Cytochalasin B; Epoprostenol; Glucuronidase; Humans; Kinetics; Leukotriene B4; Muramidase; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Prostaglandins; Superoxides | 1982 |