muramidase has been researched along with boldine* in 1 studies
1 other study(ies) available for muramidase and boldine
Article | Year |
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Antioxidant properties of the alkaloid boldine in systems undergoing lipid peroxidation and enzyme inactivation.
Boldine, in low micromolar concentrations, was able to prevent brain homogenate autooxidation, the 2,2'-azobis(2-amidinopropane)(AAP)-induced lipid peroxidation of red cell plasma membranes, and the AAP-induced inactivation of lysozyme. These results are indicative of a high reactivity of boldine towards free radicals. The analysis of the boldine effect as a function of incubation times suggests that a metabolite resulting from the interaction of boldine with free radicals also exhibits antioxidant activity, being more efficient than boldine in brain homogenate auto-oxidation and less efficient in lysozyme protection experiments. This behavior may be accounted for in terms of the relative location of the scavengers needed to afford maximal protection. Topics: Amidines; Animals; Antioxidants; Aporphines; Brain Chemistry; Dose-Response Relationship, Drug; Erythrocyte Membrane; Kinetics; Lipid Peroxidation; Luminescent Measurements; Male; Muramidase; Oxygen Consumption; Rats; Rats, Inbred Strains | 1991 |