mr 2034 has been researched along with u-50488 in 9 studies
| Studies (mr 2034) | Trials (mr 2034) | Recent Studies (post-2010) (mr 2034) | Studies (u-50488) | Trials (u-50488) | Recent Studies (post-2010) (u-50488) |
|---|---|---|---|---|---|
| 48 | 0 | 0 | 1,664 | 3 | 209 |
| Protein | Taxonomy | mr 2034 (IC50) | u-50488 (IC50) |
|---|---|---|---|
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 2.15 | |
| Kappa-type opioid receptor | Mus musculus (house mouse) | 0.0027 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 2.15 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.7171 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.0958 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 0.0537 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (77.78) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| France, CP; Woods, JH | 1 |
| Attali, B; Saya, D; Vogel, Z | 1 |
| Smith, CB | 1 |
| Bergman, J; Howell, LL; Morse, WH | 1 |
| Hart, JC; Leander, JD; Zerbe, RL | 1 |
| Dykstra, LA; Gmerek, DE; Woods, JH | 1 |
| Fitzjarrell, AT; Heath, RG; Walker, CF | 1 |
| Altura, BM; Altura, BT; Quirion, R | 1 |
| Barg, J; Levy, R; Nah, SY; Saya, D; Vogel, Z | 1 |
9 other study(ies) available for mr 2034 and u-50488
| Article | Year |
|---|---|
Respiratory effects of receptor-selective opioids in rhesus monkeys.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Alfentanil; Animals; Benzomorphans; Macaca mulatta; Narcotics; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Respiration; Tidal Volume | 1990 |
Kappa-opiate agonists inhibit adenylate cyclase and produce heterologous desensitization in rat spinal cord.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Benzomorphans; Cell Membrane; Cells, Cultured; Colforsin; Egtazic Acid; Etorphine; Ganglia, Spinal; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Male; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Sodium; Sodium Fluoride; Spinal Cord | 1989 |
New approaches to the evaluation of opioid agonists and antagonists upon the isolated, electrically stimulated mouse vas deferens preparation.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzodiazepines; Benzomorphans; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Oligopeptides; Pyrrolidines; Receptors, Opioid; Vas Deferens | 1987 |
Effects of levorphanol and several kappa-selective opioids on respiration and behavior in rhesus monkeys.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Behavior, Animal; Benzodiazepines; Benzomorphans; Carbon Dioxide; Levorphanol; Macaca mulatta; Male; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Respiration | 1988 |
Kappa agonist-induced diuresis: evidence for stereoselectivity, strain differences, independence of hydration variables and a result of decreased plasma vasopressin levels.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzomorphans; Butorphanol; Cyclazocine; Diuresis; Drinking; Ethylketocyclazocine; Female; Male; Nalorphine; Pyrrolidines; Rats; Rats, Inbred Strains; Rats, Zucker; Receptors, Opioid; Receptors, Opioid, kappa; Stereoisomerism; Vasopressins; Water Deprivation | 1987 |
Kappa opioids in rhesus monkeys. III. Dependence associated with chronic administration.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzodiazepines; Benzomorphans; Cyclazocine; Drug Tolerance; Endorphins; Ethylketocyclazocine; Macaca mulatta; Morphinans; Morphine; Narcotic Antagonists; Pentobarbital; Pyrrolidines; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors | 1987 |
Kappa opiate receptor agonists: effects on behavior and on brain function and structure in rhesus monkeys.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Behavior, Animal; Benzomorphans; Brain; Computers; Cyclazocine; Dose-Response Relationship, Drug; Electroencephalography; Ethylketocyclazocine; Evoked Potentials; Macaca mulatta; Naloxone; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa | 1984 |
Identification of benzomorphan-kappa opiate receptors in cerebral arteries which subserve relaxation.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzomorphans; Cerebral Arteries; Cyclazocine; Dinoprost; Dogs; Drug Interactions; Ethylketocyclazocine; Female; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Phencyclidine; Prostaglandins F; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa | 1984 |
Modulation of thymidine incorporation by kappa-opioid ligands in rat spinal cord-dorsal root ganglion co-cultures.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Benzeneacetamides; Benzomorphans; Cell Communication; Cells, Cultured; Cytosol; DNA; Dose-Response Relationship, Drug; Embryo, Mammalian; Ganglia, Spinal; Inositol Phosphates; Kinetics; Lithium Chloride; Neurons; Pertussis Toxin; Pyrrolidines; Rats; Receptors, Opioid, kappa; Spinal Cord; Thymidine; Time Factors; Tritium; Virulence Factors, Bordetella | 1993 |