Page last updated: 2024-09-03

mr 2034 and morphine

mr 2034 has been researched along with morphine in 13 studies

Compound Research Comparison

Studies
(mr 2034)
Trials
(mr 2034)
Recent Studies (post-2010)
(mr 2034)
Studies
(morphine)
Trials
(morphine)
Recent Studies (post-2010) (morphine)
480044,2705,2008,695

Protein Interaction Comparison

ProteinTaxonomymr 2034 (IC50)morphine (IC50)
Delta-type opioid receptorMus musculus (house mouse)0.2939
Delta-type opioid receptorRattus norvegicus (Norway rat)0.2278
Kappa-type opioid receptorMus musculus (house mouse)0.0828
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0385
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.0545
Mu-type opioid receptorHomo sapiens (human)0.122
Delta-type opioid receptorHomo sapiens (human)0.1199
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.9308
Kappa-type opioid receptorHomo sapiens (human)0.655
Mu-type opioid receptorMus musculus (house mouse)0.3305
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.202
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.25

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-199012 (92.31)18.7374
1990's0 (0.00)18.2507
2000's1 (7.69)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Iyengar, S; Kim, HS; Wood, PL1
Herz, A; Nikolarakis, K; Pfeiffer, A; Stalla, GK1
Akil, H; Houghten, RA; Lewis, ME; Walker, JM; Woods, JH; Young, EA1
Geppert, M; Illes, P; Jackisch, R1
Herz, A; Loriaux, DL; Pfeiffer, A; Pfeiffer, DG1
Lanthier, D; Leibowitz, SF; Stanley, BG1
Dykstra, LA; Gmerek, DE; Woods, JH1
Havemann, U; Kuschinsky, K1
Gmerek, DE; Woods, JH1
Apfelbaum, M; Bertiere, MC; Betoulle, D; Mandenoff, A1
Rubini, P; Schulz, R; Wüster, M1
Ensinger, HA; Gaida, W; Jennewein, HM; Merz, H; Stockhaus, K1
Nielsen, CK; Ross, FB; Smith, MT1

Other Studies

13 other study(ies) available for mr 2034 and morphine

ArticleYear
Reversal of the actions of morphine on mesocortical dopamine metabolism in the rat by the kappa agonist MR-2034: tentative mu-2 opioid control of mesocortical dopaminergic projections.
    Life sciences, 1987, Oct-05, Volume: 41, Issue:14

    Topics: Animals; Benzomorphans; Brain; Cerebral Cortex; Corpus Striatum; Dopamine; Frontal Lobe; Gyrus Cinguli; Male; Morphinans; Morphine; Olfactory Bulb; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu

1987
The role of CRF in the release of ACTH by opiate agonists and antagonists in rats.
    Brain research, 1987, Sep-22, Volume: 421, Issue:1-2

    Topics: Adrenocorticotropic Hormone; Animals; Benzomorphans; Corticotropin-Releasing Hormone; Immune Sera; Male; Morphinans; Morphine; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid

1987
[3H]dynorphin A binding and kappa selectivity of prodynorphin peptides in rat, guinea-pig and monkey brain.
    European journal of pharmacology, 1986, Mar-04, Volume: 121, Issue:3

    Topics: Alkylating Agents; Animals; Benzomorphans; Brain Chemistry; Dynorphins; Guinea Pigs; In Vitro Techniques; Macaca mulatta; Morphine; Naltrexone; Peptides; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Stereoisomerism

1986
Characterization of opioid receptors modulating noradrenaline release in the hippocampus of the rabbit.
    Journal of neurochemistry, 1986, Volume: 46, Issue:6

    Topics: Animals; Benzomorphans; Clonidine; Cyclazocine; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Ethylketocyclazocine; Hippocampus; Morphine; Norepinephrine; Rabbits; Receptors, Opioid

1986
Central kappa- and mu-opiate receptors mediate ACTH-release in rats.
    Endocrinology, 1985, Volume: 116, Issue:6

    Topics: Adrenocorticotropic Hormone; Animals; Benzomorphans; Brain; Female; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu

1985
Multiple brain sites sensitive to feeding stimulation by opioid agonists: a cannula-mapping study.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 31, Issue:4

    Topics: Animals; Benzomorphans; Brain; Brain Mapping; Dose-Response Relationship, Drug; Enkephalin, Methionine; Feeding Behavior; Male; Morphinans; Morphine; Rats; Rats, Inbred Strains; Time Factors

1988
Kappa opioids in rhesus monkeys. III. Dependence associated with chronic administration.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzodiazepines; Benzomorphans; Cyclazocine; Drug Tolerance; Endorphins; Ethylketocyclazocine; Macaca mulatta; Morphinans; Morphine; Narcotic Antagonists; Pentobarbital; Pyrrolidines; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors

1987
Locomotor activity of rats after injection of various opioids into the nucleus accumbens and the septum mediale.
    Naunyn-Schmiedeberg's archives of pharmacology, 1985, Volume: 331, Issue:2-3

    Topics: Animals; Benzomorphans; Drug Synergism; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Injections; Male; Morphine; Motor Activity; Naloxone; Narcotics; Nucleus Accumbens; Rats; Rats, Inbred Strains; Septal Nuclei; Septum Pellucidum

1985
Substitution and primary dependence studies in animals.
    Drug and alcohol dependence, 1985, Volume: 14, Issue:3-4

    Topics: Animals; Behavior, Animal; Benzomorphans; Buprenorphine; Butorphanol; Codeine; Discrimination, Psychological; Humans; Macaca mulatta; Morphinans; Morphine; Morphine Dependence; Nalbuphine; Narcotic Antagonists; Pentazocine; Piperidines; Substance Withdrawal Syndrome

1985
Difference in sensitivity of the mu and kappa systems in cafeteria rats.
    Neuropeptides, 1984, Volume: 5, Issue:1-3

    Topics: Animals; Benzomorphans; Diet; Eating; Humans; Hyperphagia; Male; Morphine; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu

1984
The preference of putative pro-enkephalins for different types of opiate receptors.
    Life sciences, 1981, Sep-21, Volume: 29, Issue:12

    Topics: Animals; Benzomorphans; Brain; Drug Tolerance; Dynorphins; Endorphins; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Fentanyl; Guinea Pigs; Ileum; Male; Mice; Morphine; Protein Precursors; Rats; Receptors, Opioid; Vas Deferens

1981
Mr 2033 CL--a novel non-morphine-like opioid analgesic.
    NIDA research monograph, 1983, Volume: 43

    Topics: Analgesics, Opioid; Animals; Benzomorphans; Humans; Mice; Morphinans; Morphine; Naloxone; Rabbits; Rats; Reaction Time; Receptors, Opioid; Receptors, Opioid, kappa; Stereotyped Behavior

1983
Incomplete, asymmetric, and route-dependent cross-tolerance between oxycodone and morphine in the Dark Agouti rat.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 295, Issue:1

    Topics: Analgesics, Opioid; Animals; Benzomorphans; Drug Tolerance; Male; Morphine; Oxycodone; Rats

2000