Compounds > moxifloxacin

Page last updated: 2024-09-04

moxifloxacin and warfarin

moxifloxacin has been researched along with warfarin in 14 studies

Compound Research Comparison

Studies (moxifloxacin)	Trials (moxifloxacin)	Recent Studies (post-2010) (moxifloxacin)	Studies (warfarin)	Trials (warfarin)	Recent Studies (post-2010) (warfarin)
3,157	552	1,690	36,573	2,143	14,728

Protein Interaction Comparison

Protein	Taxonomy	moxifloxacin (IC50)	warfarin (IC50)
Vitamin K epoxide reductase complex subunit 1	Homo sapiens (human)		0.0088

Research

Studies (14)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	7 (50.00)	29.6817
2010's	7 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Jolivette, LJ; Ward, KW	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Chang, SW; Elbe, DH	1
Arnold, LM; Ng, TM; Nissen, LR	1
Carroll, DG; Carroll, DN	1
Candevir, A; Cayli, M; Kurtaran, B; Sümbül, Z; Yildiz, F	1
Berube, C; Lee, R; Wen, A	1
Lee, WC; Yew, KL	1
Chao, CM; Lai, CC; Lin, SH	1

Reviews

2 review(s) available for moxifloxacin and warfarin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Interactions between warfarin and three commonly prescribed fluoroquinolones. The Annals of pharmacotherapy, 2008, Volume: 42, Issue:5 Topics: Aza Compounds; Ciprofloxacin; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Fluoroquinolones; Humans; International Normalized Ratio; Levofloxacin; Moxifloxacin; Ofloxacin; Quinolines; Warfarin	2008

Other Studies

12 other study(ies) available for moxifloxacin and warfarin

Article	Year
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure. Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7 Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution	2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Moxifloxacin-warfarin interaction: a series of five case reports. The Annals of pharmacotherapy, 2005, Volume: 39, Issue:2 Topics: Aged; Aged, 80 and over; Aza Compounds; Drug Interactions; Female; Fluoroquinolones; Humans; International Normalized Ratio; Male; Middle Aged; Moxifloxacin; Quinolines; Retrospective Studies; Warfarin	2005
Moxifloxacin and warfarin: additional evidence for a clinically relevant interaction. Pharmacotherapy, 2005, Volume: 25, Issue:6 Topics: Aged; Anticoagulants; Aza Compounds; Drug Interactions; Female; Fluoroquinolones; Humans; International Normalized Ratio; Male; Middle Aged; Moxifloxacin; Quinolines; Warfarin	2005
A significant interaction between moxifloxacin and warfarin in a patient with a mitral bioprosthetic valve. Heart and vessels, 2008, Volume: 23, Issue:4 Topics: Aged; Anti-Infective Agents; Anticoagulants; Aza Compounds; Bioprosthesis; Blood Coagulation; Blood Component Transfusion; Drug Interactions; Endocarditis; Fluoroquinolones; Heart Valve Prosthesis; Heart Valve Prosthesis Implantation; Humans; International Normalized Ratio; Male; Mitral Valve; Moxifloxacin; Quinolines; Warfarin	2008
Moxifloxacin-acetaminophen-warfarin interaction during bacille Calmette-Guerin treatment for bladder cancer. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2011, May-01, Volume: 68, Issue:9 Topics: Acetaminophen; Adjuvants, Immunologic; Aged, 80 and over; Analgesics, Non-Narcotic; Anti-Infective Agents; Anticoagulants; Antifibrinolytic Agents; Aza Compounds; BCG Vaccine; Drug Interactions; Fluoroquinolones; Humans; International Normalized Ratio; Male; Moxifloxacin; Quinolines; Urinary Bladder Neoplasms; Vitamin K 1; Warfarin	2011
Moxifloxacin-warfarin interaction. The Medical journal of Malaysia, 2012, Volume: 67, Issue:4 Topics: Anti-Infective Agents; Anticoagulants; Aza Compounds; Drug Interactions; Female; Fluoroquinolones; Heart Valve Diseases; Humans; International Normalized Ratio; Middle Aged; Mitral Valve; Moxifloxacin; Quinolines; Tricuspid Valve; Warfarin	2012
Abdominal wall hematoma and hemoperitoneum in an individual with concomitant use of warfarin and moxifloxacin. Journal of the American Geriatrics Society, 2013, Volume: 61, Issue:8 Topics: Abdominal Wall; Aged; Anti-Bacterial Agents; Anticoagulants; Aza Compounds; Blood Coagulation Tests; Drug Interactions; Drug Therapy, Combination; Female; Fluoroquinolones; Heart Valve Prosthesis; Hematoma; Hemoperitoneum; Humans; Mitral Valve Insufficiency; Moxifloxacin; Pneumonia, Bacterial; Quinolines; Thromboembolism; Tomography, X-Ray Computed; Warfarin	2013