Page last updated: 2024-09-04

moxifloxacin and triazoles

moxifloxacin has been researched along with triazoles in 18 studies

Compound Research Comparison

Studies
(moxifloxacin)
Trials
(moxifloxacin)
Recent Studies (post-2010)
(moxifloxacin)
Studies
(triazoles)
Trials
(triazoles)
Recent Studies (post-2010) (triazoles)
3,1575521,69025,8082,25213,501

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (16.67)29.6817
2010's12 (66.67)24.3611
2020's3 (16.67)2.80

Authors

AuthorsStudies
Davis, JD; Hackman, F; Higgins, T; Layton, G; Sudworth, D; Weissgerber, G1
Balez, S; Dumortier, T; Sechaud, R1
Bergman, AJ; Bloomfield, DM; Ghosh, K; Gottesdiener, KM; Gutierrez, MJ; Herman, GA; Hickey, L; Hreniuk, D; Krishna, R; Miller, J; Stoltz, R; Wagner, JA1
Kim, SY; Lee, YC; Yang, J1
Arnalich-Montiel, F; López-Arencibia, A; Lorenzo-Morales, J; Martín-Navarro, CM; Piñero, JE; Valladares, B1
Cutler, DL; Lin, WH; Tendolkar, A; Troyer, MD; Wang, Z; Xuan, F1
Fernandes, P; Jensen, JS; Unemo, M1
Muccioli, GG; Tulkens, PM; Van Bambeke, F; Vandevelde, NM1
Antonovsky, Y; Barrera, CM; Clark, K; Das, AF; Doreski, PA; Fernandes, P; Flores-Figueroa, J; Horwith, G; Jamieson, B; Karimjee, N; Keedy, K; Metev, H; Mitha, I; Molina, JM; Mykietiuk, A; Nitu, MF; Oldach, D; Rewerska, B; Rowe, BH; Scott, D; Sheets, A; Tanaseanu, CM; Van Rensburg, DJ1
Das, AF; Fernandes, P; File, TM; Gonong, JRV; Jamieson, BD; Keedy, K; Oldach, D; Rewerska, B; Sheets, A; Taylor, D; Vucinic-Mihailovic, V1
Darpo, B; Fernandes, P; Jamieson, BD; Keedy, K; Oldach, D; Sager, PT; Zhou, M1
Dunzo, E; Fan, L; Heber, W; Hussaini, A; Iwamoto, M; Khalilieh, SG; Liu, R; Triantafyllou, I; Yee, KL1
El-Najjar, N; Gessner, A; Hösl, J1
Chen, L; Chen, Z; Fan, Y; Gao, F; Lu, G; Ma, L1
Gao, F; Huang, G; Kong, F; Xiao, J; Ye, L1
Liu, H; Wang, X; Xu, Z; Yang, M; Zhang, Y1
Huang, QM; Kleiman, RB; Koretomo, R; Pai, SM; Yamada, H; Zhuo, R1
Chen, R; Guo, D; Liu, Y; Ma, T; Shi, X; Xu, Y; Xue, H; Zhang, J1

Trials

9 trial(s) available for moxifloxacin and triazoles

ArticleYear
Effect of single doses of maraviroc on the QT/QTc interval in healthy subjects.
    British journal of clinical pharmacology, 2008, Volume: 65 Suppl 1

    Topics: Adolescent; Adult; Anti-Infective Agents; Aza Compounds; CCR5 Receptor Antagonists; Cyclohexanes; Electrocardiography; Epidemiologic Methods; Female; Fluoroquinolones; Heart Rate; Humans; Male; Maraviroc; Middle Aged; Models, Biological; Moxifloxacin; Quinolines; Triazoles

2008
Deferasirox does not induce QT/QTc-prolongation in healthy subjects.
    International journal of clinical pharmacology and therapeutics, 2009, Volume: 47, Issue:5

    Topics: Adolescent; Adult; Aged; Area Under Curve; Aza Compounds; Benzoates; Deferasirox; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Female; Fluoroquinolones; Humans; Iron Chelating Agents; Long QT Syndrome; Male; Middle Aged; Moxifloxacin; Quinolines; Triazoles; Young Adult

2009
A thorough QTc study to assess the effect of sitagliptin, a DPP4 inhibitor, on ventricular repolarization in healthy subjects.
    Journal of clinical pharmacology, 2009, Volume: 49, Issue:8

    Topics: Adolescent; Adult; Aza Compounds; Cross-Over Studies; Dipeptidyl-Peptidase IV Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Female; Fluoroquinolones; Humans; Male; Middle Aged; Models, Biological; Moxifloxacin; Pyrazines; Quinolines; Sensitivity and Specificity; Sitagliptin Phosphate; Time Factors; Triazoles; Young Adult

2009
Preladenant, a selective adenosine A₂A receptor antagonist, is not associated with QT/QTc prolongation.
    European journal of clinical pharmacology, 2013, Volume: 69, Issue:10

    Topics: Adenosine A2 Receptor Antagonists; Adolescent; Adult; Antiparkinson Agents; Aza Compounds; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Electrocardiography; Female; Fluoroquinolones; Humans; Long QT Syndrome; Male; Middle Aged; Moxifloxacin; Pyrimidines; Quinolines; Triazoles; Young Adult

2013
Efficacy and safety of oral solithromycin versus oral moxifloxacin for treatment of community-acquired bacterial pneumonia: a global, double-blind, multicentre, randomised, active-controlled, non-inferiority trial (SOLITAIRE-ORAL).
    The Lancet. Infectious diseases, 2016, Volume: 16, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Community-Acquired Infections; Double-Blind Method; Europe; Female; Fluoroquinolones; Humans; Latin America; Macrolides; Male; Middle Aged; Moxifloxacin; North America; Pneumonia, Bacterial; South Africa; Triazoles; Young Adult

2016
SOLITAIRE-IV: A Randomized, Double-Blind, Multicenter Study Comparing the Efficacy and Safety of Intravenous-to-Oral Solithromycin to Intravenous-to-Oral Moxifloxacin for Treatment of Community-Acquired Bacterial Pneumonia.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2016, 10-15, Volume: 63, Issue:8

    Topics: Administration, Intravenous; Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Community-Acquired Infections; Comorbidity; Drug Resistance, Bacterial; Female; Fluoroquinolones; Humans; Macrolides; Male; Microbial Sensitivity Tests; Middle Aged; Moxifloxacin; Pneumonia, Bacterial; Treatment Outcome; Triazoles

2016
Solithromycin, a novel macrolide, does not prolong cardiac repolarization: a randomized, three-way crossover study in healthy subjects.
    The Journal of antimicrobial chemotherapy, 2017, Volume: 72, Issue:2

    Topics: Arrhythmias, Cardiac; Cross-Over Studies; Electrocardiography; Female; Fluoroquinolones; Healthy Volunteers; Heart Conduction System; Humans; Macrolides; Male; Moxifloxacin; Placebos; Triazoles

2017
A Randomized Trial to Assess the Effect of Doravirine on the QTc Interval Using a Single Supratherapeutic Dose in Healthy Adult Volunteers.
    Clinical drug investigation, 2017, Volume: 37, Issue:10

    Topics: Adolescent; Adult; Cross-Over Studies; Double-Blind Method; Electrocardiography; Female; Fluoroquinolones; Heart Rate; Humans; Long QT Syndrome; Male; Middle Aged; Moxifloxacin; Pyridones; Reverse Transcriptase Inhibitors; Triazoles; Young Adult

2017
Thorough QT/QTc Evaluation of the Cardiac Safety of Enarodustat (JTZ-951), an Oral Erythropoiesis-Stimulating Agent, in Healthy Adults.
    Clinical pharmacology in drug development, 2021, Volume: 10, Issue:8

    Topics: Adult; Cross-Over Studies; Drug Administration Schedule; Electrocardiography; Female; Healthy Volunteers; Heart; Heart Function Tests; Humans; Male; Middle Aged; Moxifloxacin; N-substituted Glycines; Pyridines; Triazoles; Young Adult

2021

Other Studies

9 other study(ies) available for moxifloxacin and triazoles

ArticleYear
Safety of moxifloxacin and voriconazole in corneal storage media on porcine corneal endothelial cells.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2010, Volume: 26, Issue:4

    Topics: Animals; Anti-Infective Agents; Aza Compounds; Cell Count; Cell Survival; Chondroitin Sulfates; Complex Mixtures; Cornea; Cryopreservation; Culture Media, Serum-Free; Dextrans; Endothelium, Corneal; Fluoroquinolones; Gentamicins; Moxifloxacin; Organ Preservation Solutions; Pyrimidines; Quinolines; Swine; Tissue Preservation; Triazoles; Voriconazole

2010
Evaluation of the in vitro activity of commercially available moxifloxacin and voriconazole eye-drops against clinical strains of Acanthamoeba.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2013, Volume: 251, Issue:9

    Topics: Acanthamoeba castellanii; Amebicides; Amphotericin B; Animals; Anti-Bacterial Agents; Antifungal Agents; Aza Compounds; Chlorhexidine; Colorimetry; Drug Combinations; Fluoroquinolones; HeLa Cells; Humans; Macrophages; Mice; Moxifloxacin; Ophthalmic Solutions; Parasitic Sensitivity Tests; Pyrimidines; Quinolines; Triazoles; Voriconazole

2013
In vitro activity of the new fluoroketolide solithromycin (CEM-101) against macrolide-resistant and -susceptible Mycoplasma genitalium strains.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:6

    Topics: Anti-Bacterial Agents; Azithromycin; DNA, Bacterial; DNA, Ribosomal; Doxycycline; Drug Resistance, Bacterial; Fluoroquinolones; Gonorrhea; Humans; Macrolides; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Mycoplasma genitalium; Mycoplasma Infections; Neisseria gonorrhoeae; Triazoles

2014
Modulation of the activity of moxifloxacin and solithromycin in an in vitro pharmacodynamic model of Streptococcus pneumoniae naive and induced biofilms.
    The Journal of antimicrobial chemotherapy, 2015, Volume: 70, Issue:6

    Topics: Aged; Aged, 80 and over; Albuterol; Anti-Bacterial Agents; Biofilms; Bronchodilator Agents; Chromatography, High Pressure Liquid; Drug Interactions; Female; Fluoroquinolones; Humans; Ipratropium; Macrolides; Male; Mass Spectrometry; Microbial Viability; Middle Aged; Models, Theoretical; Moxifloxacin; N-Acetylneuraminic Acid; Pneumococcal Infections; Streptococcus pneumoniae; Triazoles

2015
Liquid chromatography-tandem mass spectrometry for the quantification of moxifloxacin, ciprofloxacin, daptomycin, caspofungin, and isavuconazole in human plasma.
    Journal of pharmaceutical and biomedical analysis, 2018, Aug-05, Volume: 157

    Topics: Anti-Bacterial Agents; Antifungal Agents; Caspofungin; Chromatography, High Pressure Liquid; Ciprofloxacin; Daptomycin; Echinocandins; Fluoroquinolones; Humans; Limit of Detection; Lipopeptides; Moxifloxacin; Nitriles; Plasma; Pyridines; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Triazoles

2018
Synthesis and biological evaluation of moxifloxacin-acetyl-1,2,3-1H-triazole-methylene-isatin hybrids as potential anti-tubercular agents against both drug-susceptible and drug-resistant Mycobacterium tuberculosis strains.
    European journal of medicinal chemistry, 2019, Oct-15, Volume: 180

    Topics: Animals; Antitubercular Agents; Cell Survival; Chlorocebus aethiops; CHO Cells; Cricetulus; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Female; Isatin; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Molecular Structure; Moxifloxacin; Mycobacterium tuberculosis; Structure-Activity Relationship; Triazoles; Vero Cells

2019
Design, synthesis and antibacterial activity evaluation of moxifloxacin-amide-1,2,3-triazole-isatin hybrids.
    Bioorganic chemistry, 2019, Volume: 91

    Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Drug Design; Humans; Isatin; Molecular Docking Simulation; Molecular Structure; Moxifloxacin; Structure-Activity Relationship; Triazoles

2019
Moxifloxacin-isatin Hybrids Tethered by 1,2,3-triazole and their Anticancer Activities.
    Current topics in medicinal chemistry, 2020, Volume: 20, Issue:16

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Isatin; Molecular Structure; Moxifloxacin; Polymerization; Structure-Activity Relationship; Triazoles; Tubulin

2020
Moxifloxacin Derivatives with Potential Antibacterial Activity against Methicillin- Resistant Staphylococcus Aureus (MRSA).
    Current topics in medicinal chemistry, 2021, Volume: 21, Issue:27

    Topics: Anti-Bacterial Agents; DNA Topoisomerase IV; Fluoroquinolones; Isatin; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Moxifloxacin; Triazoles

2021