Page last updated: 2024-09-04

moxifloxacin and sulbactam

moxifloxacin has been researched along with sulbactam in 12 studies

Compound Research Comparison

Studies
(moxifloxacin)
Trials
(moxifloxacin)
Recent Studies (post-2010)
(moxifloxacin)
Studies
(sulbactam)
Trials
(sulbactam)
Recent Studies (post-2010) (sulbactam)
3,1575521,6901,844297488

Protein Interaction Comparison

ProteinTaxonomymoxifloxacin (IC50)sulbactam (IC50)
Beta-lactamase Escherichia coli6.2
Beta-lactamase Shouchella clausii0.075
Beta-lactamase Pseudomonas aeruginosa0.37
Beta-lactamase Pseudomonas aeruginosa3
Beta-lactamase Aeromonas allosaccharophila4
Beta-lactamaseStaphylococcus aureus6.5
Beta-lactamaseEnterobacter cloacae1.4
Beta-lactamase TEMEscherichia coli4.3
Beta-lactamase Acinetobacter pittii1.12
Beta-lactamase Acinetobacter pittii7.758
Beta-lactamase Pseudomonas aeruginosa3
Beta-lactamase Escherichia coli2.4

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (50.00)29.6817
2010's5 (41.67)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Calvo, A; García, R; Gómez-Lus, ML; Leturia, A; Sevillano, D; Valero, E1
Al-Nawas, B; Callaway, A; Geibel, MA; Karbach, J; Wagner, W; Willershausen, B1
Allewelt, M; Lode, H; Lorenz, J; Ott, SR; Reimnitz, P1
Huber, W; Kamereck, K; Prinz, C; Schmid, RM; Voland, P; Weber, A; Weidenbach, H; Winkle, P1
Al-Nawas, B; d'Hoedt, B; Karbach, J; Mouratidou, A1
Chen, CW; Ma, CJ; Ming, CC; Shan, YS; Wang, JY; Yeh, YS1
Akgul, O; Jean-Pierre, H; Justesen, US; Kulekci, G; Morris, T; Nagy, E; Soyletir, G; Ulger Toprak, N; Urban, E; Veloo, ACM; Wybo, I1
Heidary, G; Somsen, D1
Ikebuchi, K; Imai, K; Kawamura, T; Kodana, M; Maeda, T; Maesaki, S; Mitsutake, K; Murakami, T; Ogane, K; Onodera, A; Sakai, J; Takeuchi, S; Tarumoto, N1

Trials

2 trial(s) available for moxifloxacin and sulbactam

ArticleYear
Moxifloxacin vs ampicillin/sulbactam in aspiration pneumonia and primary lung abscess.
    Infection, 2008, Volume: 36, Issue:1

    Topics: Adult; Ampicillin; Anti-Bacterial Agents; Aza Compounds; Female; Fluoroquinolones; Gram-Negative Bacterial Infections; Gram-Negative Facultatively Anaerobic Rods; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Humans; Lung Abscess; Male; Moxifloxacin; Pneumonia, Aspiration; Quinolines; Radiography; Sulbactam

2008
Prospective, randomized, study of ampicillin-sulbactam versus moxifloxacin monotherapy for the treatment of community-acquired complicated intra-abdominal infections.
    Surgical infections, 2013, Volume: 14, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Ampicillin; Analysis of Variance; Anti-Bacterial Agents; Aza Compounds; Community-Acquired Infections; Female; Fluoroquinolones; Humans; Intraabdominal Infections; Logistic Models; Male; Middle Aged; Moxifloxacin; Prospective Studies; Quinolines; Risk Factors; Sulbactam; Taiwan; Treatment Outcome; Young Adult

2013

Other Studies

10 other study(ies) available for moxifloxacin and sulbactam

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
[Activity of new fluoroquinolones against clinical isolates of Acinetobacter baumannii].
    Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2001, Volume: 14, Issue:4

    Topics: Acinetobacter; Acinetobacter Infections; Ampicillin; Anti-Infective Agents; Aza Compounds; Cefepime; Cephalosporins; Ciprofloxacin; Colistin; Fluoroquinolones; Gatifloxacin; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Moxifloxacin; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Opportunistic Infections; Quinolines; Sulbactam; Thienamycins

2001
Antibiotic resistance testing of the total implant-associated micro-flora and its pure isolates.
    European journal of medical research, 2007, Mar-26, Volume: 12, Issue:3

    Topics: Ampicillin; Anti-Bacterial Agents; Aza Compounds; Azithromycin; Bacteria, Anaerobic; Dental Implants; Dental Plaque; Dose-Response Relationship, Drug; Drug Combinations; Drug Resistance, Bacterial; Female; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Cocci; Gram-Positive Rods; Humans; In Vitro Techniques; Male; Microbial Sensitivity Tests; Moxifloxacin; Penicillin G; Quinolines; Sulbactam

2007
In vitro activity of moxifloxacin and piperacillin/sulbactam against pathogens of acute cholangitis.
    World journal of gastroenterology, 2008, May-28, Volume: 14, Issue:20

    Topics: Acute Disease; Aged; Aged, 80 and over; Anti-Bacterial Agents; Aza Compounds; Bile; Cholangitis; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Enterococcus; Escherichia coli; Female; Fluoroquinolones; Humans; Klebsiella; Male; Middle Aged; Moxifloxacin; Piperacillin; Prospective Studies; Quinolines; Sulbactam

2008
Antibiotic susceptibility of cocultures in polymicrobial infections such as peri-implantitis or periodontitis: an in vitro model.
    Journal of periodontology, 2011, Volume: 82, Issue:9

    Topics: Acetamides; Actinobacillus Infections; Aggregatibacter actinomycetemcomitans; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Azithromycin; Capnocytophaga; Coculture Techniques; Coinfection; Drug Resistance, Bacterial; Fluoroquinolones; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Linezolid; Metronidazole; Microbial Interactions; Minocycline; Moxifloxacin; Oxazolidinones; Penicillin G; Peptostreptococcus; Peri-Implantitis; Periodontitis; Quinolines; Sulbactam

2011
A multicenter survey of antimicrobial susceptibility of Prevotella species as determined by Etest methodology.
    Anaerobe, 2018, Volume: 52

    Topics: Ampicillin; Anti-Bacterial Agents; Bacteroidaceae Infections; Clindamycin; Disk Diffusion Antimicrobial Tests; Fluoroquinolones; Humans; Kuwait; Meropenem; Metronidazole; Moxifloxacin; Prevotella; Sulbactam; Thienamycins; Turkey

2018
Rapid onset of orbital cellulitis after uncomplicated strabismus surgery.
    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2019, Volume: 23, Issue:5

    Topics: Administration, Ophthalmic; Ampicillin; Anti-Bacterial Agents; Child; Drug Therapy, Combination; Esotropia; Eye Infections, Bacterial; Humans; Male; Moxifloxacin; Oculomotor Muscles; Ophthalmic Solutions; Orbital Cellulitis; Postoperative Complications; Streptococcal Infections; Streptococcus pyogenes; Sulbactam; Tomography, X-Ray Computed; Vancomycin

2019
Antimicrobial susceptibility and prevalence of resistance genes in Bacteroides fragilis isolated from blood culture bottles in two tertiary care hospitals in Japan.
    Anaerobe, 2020, Volume: 64

    Topics: Ampicillin; Anti-Bacterial Agents; Bacterial Proteins; Bacteroides fragilis; Bacteroides Infections; beta-Lactamases; Blood Culture; DNA Transposable Elements; Doripenem; Drug Resistance, Multiple, Bacterial; Genes, Bacterial; Humans; Imipenem; Japan; Meropenem; Metronidazole; Microbial Sensitivity Tests; Moxifloxacin; Piperacillin, Tazobactam Drug Combination; Prevalence; Sulbactam; Tertiary Care Centers

2020