Page last updated: 2024-09-04

moxifloxacin and quinacrine

moxifloxacin has been researched along with quinacrine in 4 studies

Compound Research Comparison

Studies
(moxifloxacin)
Trials
(moxifloxacin)
Recent Studies (post-2010)
(moxifloxacin)
Studies
(quinacrine)
Trials
(quinacrine)
Recent Studies (post-2010) (quinacrine)
3,1575521,6904,05165289

Protein Interaction Comparison

ProteinTaxonomymoxifloxacin (IC50)quinacrine (IC50)
cystic fibrosis transmembrane conductance regulatorHomo sapiens (human)19.88
Major prion proteinMus musculus (house mouse)0.0951
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)2.896
Muscarinic acetylcholine receptor M2Homo sapiens (human)0.964
Muscarinic acetylcholine receptor M4Homo sapiens (human)1.983
Muscarinic acetylcholine receptor M1Rattus norvegicus (Norway rat)4.5
Muscarinic acetylcholine receptor M3Rattus norvegicus (Norway rat)4.5
Muscarinic acetylcholine receptor M4Rattus norvegicus (Norway rat)4.5
Muscarinic acetylcholine receptor M5Rattus norvegicus (Norway rat)4.5
Muscarinic acetylcholine receptor M5Homo sapiens (human)3.736
Alpha-2A adrenergic receptorHomo sapiens (human)2.28
Muscarinic acetylcholine receptor M2Rattus norvegicus (Norway rat)4.5
Muscarinic acetylcholine receptor M1Homo sapiens (human)1.489
Alpha-2B adrenergic receptorHomo sapiens (human)1.825
Alpha-2C adrenergic receptorHomo sapiens (human)3.857
Muscarinic acetylcholine receptor M3Homo sapiens (human)1.255
AcetylcholinesteraseHomo sapiens (human)2.667
Sodium-dependent noradrenaline transporter Homo sapiens (human)2.896
Histamine H2 receptorHomo sapiens (human)3.535
Alpha-1D adrenergic receptorHomo sapiens (human)2.065
5-hydroxytryptamine receptor 2AHomo sapiens (human)2.663
D(3) dopamine receptorHomo sapiens (human)1.318
Aldehyde oxidase 1Oryctolagus cuniculus (rabbit)10
CholinesteraseEquus caballus (horse)4.5
Aldehyde oxidaseHomo sapiens (human)3.3
Cyclic GMP-AMP synthaseHomo sapiens (human)7

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1

Other Studies

4 other study(ies) available for moxifloxacin and quinacrine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
    Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10

    Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012