Page last updated: 2024-09-04

moxifloxacin and melagatran

moxifloxacin has been researched along with melagatran in 3 studies

Compound Research Comparison

Studies
(moxifloxacin)
Trials
(moxifloxacin)
Recent Studies (post-2010)
(moxifloxacin)
Studies
(melagatran)
Trials
(melagatran)
Recent Studies (post-2010) (melagatran)
3,1575521,6901853219

Protein Interaction Comparison

ProteinTaxonomymoxifloxacin (IC50)melagatran (IC50)
ProthrombinHomo sapiens (human)0.5239
PlasminogenHomo sapiens (human)3.06
Cationic trypsinBos taurus (cattle)0.0112
Vitamin K-dependent protein CHomo sapiens (human)1.3
Trypsin-1Homo sapiens (human)0.0119
Trypsin-2Homo sapiens (human)0.0119
Coagulation factor VIIHomo sapiens (human)3.3
Trypsin-3Homo sapiens (human)0.0119

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1

Other Studies

3 other study(ies) available for moxifloxacin and melagatran

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010