moxifloxacin has been researched along with ketoconazole in 16 studies
| Studies (moxifloxacin) | Trials (moxifloxacin) | Recent Studies (post-2010) (moxifloxacin) | Studies (ketoconazole) | Trials (ketoconazole) | Recent Studies (post-2010) (ketoconazole) |
|---|---|---|---|---|---|
| 3,157 | 552 | 1,690 | 6,202 | 706 | 1,269 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (43.75) | 29.6817 |
| 2010's | 9 (56.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Keserü, GM | 1 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Cho, SH; Franzblau, SG; Hwang, CH; Pauli, GF; Wan, B; Warit, S | 1 |
| Jia, L; Sun, H | 1 |
| Chlipala, G; Krunic, A; Mo, S; Orjala, J | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Sen, S; Sinha, N | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Agin, M; Darpo, B; Gray, P; Jorkasky, DK; Kazierad, DJ; Layton, G; Muirhead, G | 1 |
| Amantea, MA; Nickens, DJ; Raber, SR; Reynolds, RR; Sarapa, N | 1 |
| Abbas, R; Burns, J; Hug, B; Leister, C; Sonnichsen, D | 1 |
| Abbas, R; Hug, BA; Leister, C; Sonnichsen, D | 1 |
| Darpo, B; Ferber, G; Sager, P; Sumeray, M; Zhou, M | 1 |
| Darpo, B; Ferber, G; Zhou, M | 1 |
| Farahat, HG; Mandour, SS; Marey, HM | 1 |
1 review(s) available for moxifloxacin and ketoconazole
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
5 trial(s) available for moxifloxacin and ketoconazole
| Article | Year |
|---|---|
Man versus machine: is there an optimal method for QT measurements in thorough QT studies?
Topics: Adolescent; Adult; Aza Compounds; Control Groups; Cross-Over Studies; Electrocardiography; Female; Fluoroquinolones; Humans; Ketoconazole; Long QT Syndrome; Male; Middle Aged; Moxifloxacin; Quinolines; Reproducibility of Results; Research Design; Signal Processing, Computer-Assisted | 2006 |
Ritonavir 100 mg does not cause QTc prolongation in healthy subjects: a possible role as CYP3A inhibitor in thorough QTc studies.
Topics: Adult; Aza Compounds; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Evaluation, Preclinical; Drug Therapy, Combination; Electrocardiography; Female; Fluoroquinolones; Heart Rate; HIV Protease Inhibitors; Humans; Imidazoles; Ketoconazole; Liver; Long QT Syndrome; Male; Middle Aged; Moxifloxacin; Quinolines; Reference Values; Reproducibility of Results; Research Design; Reverse Transcriptase Inhibitors; Ritonavir; Sulfur Compounds; Treatment Outcome | 2008 |
A single-dose, crossover, placebo- and moxifloxacin-controlled study to assess the effects of neratinib (HKI-272) on cardiac repolarization in healthy adult subjects.
Topics: Adolescent; Adult; Anti-Infective Agents; Antineoplastic Agents; Aza Compounds; Cross-Over Studies; Electrocardiography; Female; Fluoroquinolones; Heart; Humans; Ketoconazole; Male; Middle Aged; Moxifloxacin; Placebos; Quinolines; Young Adult | 2010 |
A randomized, crossover, placebo- and moxifloxacin-controlled study to evaluate the effects of bosutinib (SKI-606), a dual Src/Abl tyrosine kinase inhibitor, on cardiac repolarization in healthy adult subjects.
Topics: Adolescent; Adult; Aniline Compounds; Aza Compounds; Cross-Over Studies; Double-Blind Method; Electrocardiography; Female; Fluoroquinolones; Heart; Humans; Ketoconazole; Male; Middle Aged; Moxifloxacin; Nitriles; Quinolines; Young Adult | 2012 |
Lomitapide at supratherapeutic plasma levels does not prolong the Qtc interval--results from a TQT study with moxifloxacin and ketoconazole.
Topics: 14-alpha Demethylase Inhibitors; Adolescent; Adult; Aza Compounds; Benzimidazoles; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Electrocardiography; Female; Fluoroquinolones; Heart Rate; Humans; Ketoconazole; Male; Middle Aged; Moxifloxacin; Quinolines; Reference Values; Time Factors; Topoisomerase II Inhibitors; Young Adult | 2013 |
10 other study(ies) available for moxifloxacin and ketoconazole
| Article | Year |
|---|---|
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis.
Topics: Anti-Bacterial Agents; Antitubercular Agents; DNA, Bacterial; Drug Evaluation, Preclinical; Mycobacterium tuberculosis; Oxygen | 2007 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
Antimicrobial ambiguine isonitriles from the cyanobacterium Fischerella ambigua.
Topics: Anti-Bacterial Agents; Bacillus anthracis; Cyanobacteria; Indole Alkaloids; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nuclear Magnetic Resonance, Biomolecular | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Detection of QTc effects in small studies--implications for replacing the thorough QT study.
Topics: Cytochrome P-450 CYP3A Inhibitors; Dose-Response Relationship, Drug; Electrocardiography; Fluoroquinolones; Heart Rate; Humans; Ketoconazole; Moxifloxacin; Topoisomerase II Inhibitors | 2015 |
Resistant Microbial Keratitis in South Nile Delta, Egypt: Influence of Regional Risk Factors.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteria; Child; Child, Preschool; Climate; Corneal Ulcer; Cross-Sectional Studies; Drug Resistance, Bacterial; Drug Resistance, Fungal; Drug Therapy, Combination; Egypt; Eye Infections, Bacterial; Eye Infections, Fungal; Female; Fluoroquinolones; Fungi; Geography; Humans; Incidence; Infant; Infant, Newborn; Ketoconazole; Male; Middle Aged; Moxifloxacin; Natamycin; Prospective Studies; Risk Factors; Social Class | 2016 |