Page last updated: 2024-09-04

moxifloxacin and ibuprofen

moxifloxacin has been researched along with ibuprofen in 12 studies

Compound Research Comparison

Studies
(moxifloxacin)
Trials
(moxifloxacin)
Recent Studies (post-2010)
(moxifloxacin)
Studies
(ibuprofen)
Trials
(ibuprofen)
Recent Studies (post-2010) (ibuprofen)
3,1575521,69010,2451,7814,267

Protein Interaction Comparison

ProteinTaxonomymoxifloxacin (IC50)ibuprofen (IC50)
Prostaglandin G/H synthase 1 Bos taurus (cattle)2.9
Prostaglandin G/H synthase 2 Bos taurus (cattle)1.1
AlbuminBos taurus (cattle)3
Prostaglandin G/H synthase 1Ovis aries (sheep)4.0919
Prostaglandin G/H synthase 1Mus musculus (house mouse)0.22
Prostaglandin G/H synthase 1Homo sapiens (human)1.6273
Caspase-1Homo sapiens (human)7.2667
Substance-P receptorCavia porcellus (domestic guinea pig)1.1
Prostaglandin G/H synthase 2Homo sapiens (human)3.0687
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)1.3
Aldo-keto reductase family 1 member C3Homo sapiens (human)10
Caspase-3Homo sapiens (human)7.2667
Caspase-4Homo sapiens (human)7.2667
4-aminobutyrate aminotransferase, mitochondrialRattus norvegicus (Norway rat)1.1
Caspase-5Homo sapiens (human)7.2667
Caspase-9Homo sapiens (human)7.2667
Prostaglandin G/H synthase 2Ovis aries (sheep)1.1375
Mu-type opioid receptorCavia porcellus (domestic guinea pig)2.9
Fatty-acid amide hydrolase 1Rattus norvegicus (Norway rat)5
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.54
Solute carrier family 22 member 6Homo sapiens (human)8
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)1.3

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (25.00)29.6817
2010's9 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Bellman, K; Knegtel, RM; Settimo, L1
Guo, M; Li, C; Li, YR; Liu, JC; Piao, HR; Sun, LP; Zhang, TY; Zheng, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Chi, KQ; Liu, HY; Piao, HR; Sun, LP; Wei, ZY; Yu, ZK; Zheng, CJ1
Coleman, EJ; Mandell, GL1
Estrela, C; Puente, CG; Regalado Farreras, DC1
Ashfaq, M; Faizan Nazar, M; Iqbal, J; Mulla, SI; Mustafa, G; Nawaz Khan, K; Saif Ur Rehman, M; Sun, Q; Yu, CP1

Reviews

1 review(s) available for moxifloxacin and ibuprofen

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

11 other study(ies) available for moxifloxacin and ibuprofen

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Synthesis and biological evaluation of 1,3-diaryl pyrazole derivatives as potential antibacterial and anti-inflammatory agents.
    Bioorganic & medicinal chemistry letters, 2015, Nov-15, Volume: 25, Issue:22

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Candida albicans; Drug Resistance, Multiple, Bacterial; Furans; Gram-Negative Bacteria; Gram-Positive Cocci; Ibuprofen; Indomethacin; Mice; Pyrazoles

2015
Synthesis and biological evaluation of chalcone derivatives containing aminoguanidine or acylhydrazone moieties.
    Bioorganic & medicinal chemistry letters, 2016, 12-15, Volume: 26, Issue:24

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Candida albicans; Cell Line; Cell Proliferation; Chalcone; Dose-Response Relationship, Drug; Guanidines; Humans; Hydrazones; Microbial Sensitivity Tests; Molecular Structure; Salmonella typhimurium; Structure-Activity Relationship

2016
Effect of antipyretic agents on uptake, transport, and release of antimicrobial agents by human polymorphonuclear leukocytes.
    The Journal of infectious diseases, 2002, May-01, Volume: 185, Issue:9

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Aspirin; Aza Compounds; Azithromycin; Biological Transport; Cell Movement; Fluoroquinolones; Humans; Ibuprofen; Microbial Sensitivity Tests; Moxifloxacin; Neutrophils; Quinolines

2002
Sodium hypochlorite chemical burn in an endodontist's eye during canal treatment using operating microscope.
    Journal of endodontics, 2014, Volume: 40, Issue:8

    Topics: Accidents, Occupational; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Anti-Inflammatory Agents; Burns, Chemical; Corneal Ulcer; Cyclopentolate; Dentists; Eye Burns; Female; Fluoroquinolones; Follow-Up Studies; Humans; Ibuprofen; Loteprednol Etabonate; Microsurgery; Moxifloxacin; Mydriatics; Occupational Diseases; Prednisolone; Root Canal Irrigants; Root Canal Preparation; Sodium Hypochlorite; Therapeutic Irrigation; Young Adult

2014
Ecological risk assessment of pharmaceuticals in the receiving environment of pharmaceutical wastewater in Pakistan.
    Ecotoxicology and environmental safety, 2017, Volume: 136

    Topics: Animals; Diclofenac; Ecology; Environmental Monitoring; Fishes; Fluoroquinolones; Gemifloxacin; Ibuprofen; Moxifloxacin; Naphthyridines; Pakistan; Risk Assessment; Sewage; Wastewater; Water Pollutants, Chemical

2017