Compounds > moxifloxacin
Page last updated: 2024-09-04

moxifloxacin and guanfacine

moxifloxacin has been researched along with guanfacine in 5 studies

Compound Research Comparison

Studies
(moxifloxacin)		Trials
(moxifloxacin)		Recent Studies (post-2010)
(moxifloxacin)		Studies
(guanfacine)		Trials
(guanfacine)		Recent Studies (post-2010) (guanfacine)
3,1575521,690784180273

Protein Interaction Comparison

ProteinTaxonomymoxifloxacin (IC50)guanfacine (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)1.453
Alpha-2A adrenergic receptorHomo sapiens (human)0.134
Alpha-2B adrenergic receptorHomo sapiens (human)0.249
Alpha-2C adrenergic receptorHomo sapiens (human)6.447
5-hydroxytryptamine receptor 2AHomo sapiens (human)3.014
5-hydroxytryptamine receptor 2CHomo sapiens (human)1.453
5-hydroxytryptamine receptor 2BHomo sapiens (human)2.098

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Fossa, AA; Martin, P; Purkayastha, J; Robinson, A; Zhou, M1

Reviews

1 review(s) available for moxifloxacin and guanfacine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for moxifloxacin and guanfacine

ArticleYear
Use of ECG restitution (beat-to-beat QT-TQ interval analysis) to assess arrhythmogenic risk of QTc prolongation with guanfacine.
    Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2014, Volume: 19, Issue:6

    Topics: Adrenergic alpha-2 Receptor Agonists; Arrhythmias, Cardiac; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography, Ambulatory; Female; Fluoroquinolones; Guanfacine; Humans; Long QT Syndrome; Male; Moxifloxacin; Reference Values; Retrospective Studies; Risk Assessment

2014

Other Studies

3 other study(ies) available for moxifloxacin and guanfacine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010