Page last updated: 2024-09-04

moxifloxacin and disulfiram

moxifloxacin has been researched along with disulfiram in 4 studies

Compound Research Comparison

Studies
(moxifloxacin)
Trials
(moxifloxacin)
Recent Studies (post-2010)
(moxifloxacin)
Studies
(disulfiram)
Trials
(disulfiram)
Recent Studies (post-2010) (disulfiram)
3,1575521,6903,776175723

Protein Interaction Comparison

ProteinTaxonomymoxifloxacin (IC50)disulfiram (IC50)
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonasePlasmodium berghei10.1
Spike glycoproteinBetacoronavirus England 19.35
Replicase polyprotein 1abBetacoronavirus England 19.35
type-1 angiotensin II receptorHomo sapiens (human)6.637
perilipin-5Homo sapiens (human)1.622
perilipin-1Homo sapiens (human)6.959
apelin receptorHomo sapiens (human)2.63
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform aHomo sapiens (human)4.2905
bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferaseMycobacterium tuberculosis H37Rv85.03
Transmembrane protease serine 2Homo sapiens (human)9.35
Bile salt export pumpHomo sapiens (human)10
Carbamate kinaseGiardia intestinalis0.6
Retinal dehydrogenase 1Homo sapiens (human)0.13
Aldehyde dehydrogenase, mitochondrialHomo sapiens (human)3.4
Cytochrome P450 1A2Homo sapiens (human)4
Procathepsin LHomo sapiens (human)9.35
Alpha-2A adrenergic receptorHomo sapiens (human)4.904
Fructose-1,6-bisphosphatase 1Homo sapiens (human)1.3756
Replicase polyprotein 1aSevere acute respiratory syndrome-related coronavirus9.35
Replicase polyprotein 1abHuman coronavirus 229E9.35
Replicase polyprotein 1abSevere acute respiratory syndrome-related coronavirus9.35
Adenosine receptor A3Homo sapiens (human)0.356
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 26.9171
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.356
Alpha-2B adrenergic receptorHomo sapiens (human)3.218
D(1A) dopamine receptorHomo sapiens (human)2.158
D(4) dopamine receptorHomo sapiens (human)3.15
C-X-C chemokine receptor type 2Homo sapiens (human)6.013
Mitogen-activated protein kinase 3 Homo sapiens (human)1.51
Protein-lysine 6-oxidaseHomo sapiens (human)0.32
Lysine-specific demethylase 5AHomo sapiens (human)10
Caspase-1Homo sapiens (human)1.8
Mu-type opioid receptorHomo sapiens (human)3.511
D(3) dopamine receptorHomo sapiens (human)1.084
Kappa-type opioid receptorHomo sapiens (human)6.103
C-C chemokine receptor type 2Homo sapiens (human)2.468
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.356
C-C chemokine receptor type 4Homo sapiens (human)8.395
Gasdermin-DHomo sapiens (human)0.4
Lysyl oxidase homolog 3Homo sapiens (human)0.093
Spike glycoproteinSevere acute respiratory syndrome-related coronavirus9.35
Sodium-dependent dopamine transporter Homo sapiens (human)4.637
NACHT, LRR and PYD domains-containing protein 3 Mus musculus (house mouse)3
Lysyl oxidase homolog 4Homo sapiens (human)0.059
Histone-lysine N-methyltransferase EHMT2Homo sapiens (human)0.6
Monoglyceride lipaseHomo sapiens (human)0.8095
Angiotensin-converting enzyme 2 Homo sapiens (human)9.35
Gasdermin-DMus musculus (house mouse)0.4
Histone-lysine N-methyltransferase EHMT1Homo sapiens (human)1.6
Lysyl oxidase homolog 2Homo sapiens (human)0.15
large T antigenBetapolyomavirus macacae10.73

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Chen, J; Gao, K; Huang, F; Tepe, JJ; Wang, R; Wei, GW1

Reviews

1 review(s) available for moxifloxacin and disulfiram

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

3 other study(ies) available for moxifloxacin and disulfiram

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Perspectives on SARS-CoV-2 Main Protease Inhibitors.
    Journal of medicinal chemistry, 2021, 12-09, Volume: 64, Issue:23

    Topics: Antiviral Agents; Coronavirus 3C Proteases; Humans; Protease Inhibitors

2021