Page last updated: 2024-09-04

moxifloxacin and dihydroergotamine

moxifloxacin has been researched along with dihydroergotamine in 4 studies

Compound Research Comparison

Studies
(moxifloxacin)
Trials
(moxifloxacin)
Recent Studies (post-2010)
(moxifloxacin)
Studies
(dihydroergotamine)
Trials
(dihydroergotamine)
Recent Studies (post-2010) (dihydroergotamine)
3,1575521,6901,450241116

Protein Interaction Comparison

ProteinTaxonomymoxifloxacin (IC50)dihydroergotamine (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.09
Cytochrome P450 3A4Homo sapiens (human)3.9996
Alpha-2A adrenergic receptorHomo sapiens (human)0.001
D(2) dopamine receptorHomo sapiens (human)0.0089
Alpha-2B adrenergic receptorHomo sapiens (human)0.0039
Alpha-2C adrenergic receptorHomo sapiens (human)0.01
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.0007
D(1A) dopamine receptorHomo sapiens (human)2.395
Alpha-1D adrenergic receptorHomo sapiens (human)0.029
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.008
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.09
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.0007
D(3) dopamine receptorHomo sapiens (human)0.0053
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.0068
5-hydroxytryptamine receptor 6Homo sapiens (human)0.0032
Multidrug and toxin extrusion protein 1Homo sapiens (human)2.8

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Chen, J; Gao, K; Huang, F; Tepe, JJ; Wang, R; Wei, GW1
Haugen, G; Kellerman, DJ; Kori, S; Voloshko, P1

Reviews

1 review(s) available for moxifloxacin and dihydroergotamine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for moxifloxacin and dihydroergotamine

ArticleYear
Effects of a supratherapeutic dose of investigational orally inhaled dihydroergotamine (MAP0004) on QT interval: a randomized, double-blind, active- and placebo-controlled crossover study in healthy volunteers.
    Clinical therapeutics, 2012, Volume: 34, Issue:9

    Topics: Administration, Inhalation; Adult; Aza Compounds; Cross-Over Studies; Dihydroergotamine; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Female; Fluoroquinolones; Humans; Long QT Syndrome; Male; Middle Aged; Moxifloxacin; Quinolines; Vasoconstrictor Agents; Young Adult

2012

Other Studies

2 other study(ies) available for moxifloxacin and dihydroergotamine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Perspectives on SARS-CoV-2 Main Protease Inhibitors.
    Journal of medicinal chemistry, 2021, 12-09, Volume: 64, Issue:23

    Topics: Antiviral Agents; Coronavirus 3C Proteases; Humans; Protease Inhibitors

2021